Patents by Inventor Zihong Guo
Zihong Guo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10376711Abstract: Light sources are incorporated into a guidewire for enabling the ability to render light therapy be added to catheters that do not have that capability. In one exemplary embodiment, a solid guidewire includes a conductive core, and light sources are added to compartments formed in a distal end of the guidewire. In another exemplary embodiment, a light source array is included in a distal end of a hollow guidewire. A plurality of openings are formed into the walls of the hollow guidewire surrounding the array, enabling light to pass through the openings. Conductors extend from the array though the hollow center of the guidewire, to a proximal end of the hollow guidewire. The hollow guidewire can be coated with a conductive material, so that the coating on the guidewire serves as a conductor.Type: GrantFiled: August 6, 2007Date of Patent: August 13, 2019Assignee: LIGHT SCIENCES ONCOLOGY INC.Inventors: Phillip Burwell, Zihong Guo, Jennifer K. Matson, Steven Ross Daly, David B. Shine, Gary Lichttenegger, Jean M. Bishop, Nick Yeo, Hugh Narciso
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Publication number: 20160213945Abstract: A photoreactive agent and a drug therapy device including a support member configured to pass through a urethra having proximal and distal ends and a longitudinal internal lumen. A light generator carried by the support member, potted within the lumen, and positioned within the urethra to deliver light to the prostate. The light generator generates a light band with a peak at a preselected wavelength. A power source external to the support member powers the light generator. The positioning element locates the support member within the urethra. A transparent/translucent, integral window is positioned proximate to the prostate and allows light to pass through. The window extends 360 degrees radially from the support member. The light generator has at least LEDs or LOs having a dimension of approximately 0.3 mm×0.3 mm×0.1 mm (length×width×thickness).Type: ApplicationFiled: April 5, 2016Publication date: July 28, 2016Applicant: PURDUE PHARMACEUTICAL PRODUCTS L.P.Inventors: Phillip Burwell, Zihong Guo, Jennifer K. Matson, Steven Ross Daly, David B. Shine, Gary Lichttenegger, Jean Bishop, Nick Yeo, Hugh Narciso, Llew Keltner, Jay Winship, Erik Hagstrom, Frank Zheng, James C. Chen, Joseph M. Hobbs
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Patent number: 9205969Abstract: A substantially thermally sealed storage container includes an outer assembly, including one or more sections of ultra efficient insulation material substantially defining at least one thermally sealed storage region, and an inner assembly, including at least one heat sink unit within the at least one thermally sealed storage region, and at least one stored material dispenser unit, wherein the at least one stored material dispenser unit includes one or more interlocks.Type: GrantFiled: February 8, 2010Date of Patent: December 8, 2015Assignee: TOKITAE LLCInventors: Geoffrey F. Deane, Lawrence Morgan Fowler, William Gates, Zihong Guo, Roderick A. Hyde, Edward K. Y. Jung, Jordin T. Kare, Nathan P. Myhrvold, Nathan Pegram, Nels R. Peterson, Clarence T. Tegreene, Charles Whitmer, Lowell L. Wood, Jr.
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Patent number: 9139351Abstract: Substantially thermally sealed containers including flexible connectors joining an aperture in the exterior of the container to an aperture in a substantially thermally sealed storage region within the container are described. The flexible connectors include a duct forming an elongated thermal pathway between the exterior of the container and the substantially thermally sealed storage region within the container. The flexible connectors include compression units mated to each end of the duct and a plurality of compression strands connected between the compression units.Type: GrantFiled: November 29, 2010Date of Patent: September 22, 2015Assignee: TOKITAE LLCInventors: Fong-Li Chou, Geoffrey F. Deane, William Gates, Zihong Guo, Roderick A. Hyde, Edward K. Y. Jung, Nathan P. Myhrvold, Nels R. Peterson, Clarence T. Tegreene, Charles Whitmer, Lowell L. Wood, Jr.
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Patent number: 8685071Abstract: A method of manufacture and medical apparatus that provides an apparatus useful in illuminating at least a portion of a lumen of a body. The apparatus includes an elongated flexible member and a polymer encasement portion encasing a plurality of light emitters. The light emitters may be electrically coupled to one another without the use of wire bonds, and in some embodiments may be coupled without intervening electrical paths or traces. A maximum cross-sectional dimension of the polymer encasement portion may be less than twice a dimension of one of the light emitters. In some embodiments the maximum cross-sectional dimension is less than or equal to the sum of the dimension of one of the light emitters and a marginal dimension by which an outer portion of the polymer encasement portion extends beyond the light emitter. Light emitters may be arranged linearly, helically or in partially overlapping back-to-back relation.Type: GrantFiled: February 21, 2012Date of Patent: April 1, 2014Assignee: Purdue Pharmaceutical Products L.P.Inventors: Phillip Burwell, James C. Chen, Zihong Guo, Steven R. Daly, David B. Shine, Gary Lichttenegger, Jennifer K. Matson, Jean Bishop, Nick Yeo, Hugh Narciso
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Publication number: 20130319900Abstract: The present disclosure relates to vessels and processes that may be used to fabricate vessels.Type: ApplicationFiled: May 31, 2012Publication date: December 5, 2013Inventors: Lawrence Morgan Fowler, Zihong Guo, Jenny Hu, John Arthur Ohrt
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Publication number: 20130319899Abstract: The present disclosure relates to vessels and processes that may be used to fabricate vessels.Type: ApplicationFiled: May 31, 2012Publication date: December 5, 2013Inventors: Lawrence Morgan Fowler, Zihong Guo, Jenny Hu, John Arthur Ohrt
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Publication number: 20120315364Abstract: The present disclosure relates to methods, systems, and devices that may be used to heat treat and store one or more fluids.Type: ApplicationFiled: June 8, 2012Publication date: December 13, 2012Inventors: Cary Richard Champlin, Lawrence Morgan Fowler, Zihong Guo, Jenny E. Hu, Ian Fletcher Kent, Ian Murray, Nathan John Pegram, Shannon Weise Stone, Sarah Patricia Walters, Lowell L. Wood, JR., Ozgur Emek Yildirim, Christopher C. Young
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Patent number: 8235975Abstract: A light transmission system to provide photodynamic treatment to a patient includes a single use integrated control module and catheter assembly having a plurality of light emitting diodes (LEDs) to transmit light toward target cells within a patient. The integrated light catheter and control module are used in combination with a light activated drug. Selected operating parameters may be programmed into the control module, or it may be wirelessly programmable in situ prior to use to allow user flexibility to tailor treatment for a particular patient or condition. Among the features that prevent reuse are that the control module lacks access to recharge the power source, and it may include a deactivation module that destroys circuitry or software when triggered. To prevent patient interference when in use, the control module may also be configured to selectively deactivate.Type: GrantFiled: October 14, 2011Date of Patent: August 7, 2012Assignee: Light Sciences Oncology, Inc.Inventors: James C. Chen, Steven R. Daly, Zihong Guo, Llew Keltner, Jeffrey R. Storm
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Publication number: 20120149986Abstract: A method of manufacture and medical apparatus that provides an apparatus useful in illuminating at least a portion of a lumen of a body. The apparatus includes an elongated flexible member and a polymer encasement portion encasing a plurality of light emitters. The light emitters may be electrically coupled to one another without the use of wire bonds, and in some embodiments may be coupled without intervening electrical paths or traces. A maximum cross-sectional dimension of the polymer encasement portion may be less than twice a dimension of one of the light emitters. In some embodiments the maximum cross-sectional dimension is less than or equal to the sum of the dimension of one of the light emitters and a marginal dimension by which an outer portion of the polymer encasement portion extends beyond the light emitter. Light emitters may be arranged linearly, helically or in partially overlapping back-to-back relation.Type: ApplicationFiled: February 21, 2012Publication date: June 14, 2012Applicant: Light Sciences Oncology, Inc.Inventors: Phillip Burwell, James C. Chen, Zihong Guo, Steven R. Daly, David B. Shine, Gary Lichtlenegger, Jennifer K. Matson, Jean Bishop, Nick YEO, Hugh Narciso
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Publication number: 20120089207Abstract: A light transmission system to provide photodynamic treatment to a patient includes a single use integrated control module and catheter assembly having a plurality of light emitting diodes (LEDs) to transmit light toward target cells within a patient. The integrated light catheter and control module are used in combination with a light activated drug. Selected operating parameters may be programmed into the control module, or it may be wirelessly programmable in situ prior to use to allow user flexibility to tailor treatment for a particular patient or condition. Among the features that prevent reuse are that the control module lacks access to recharge the power source, and it may include a deactivation module that destroys circuitry or software when triggered. To prevent patient interference when in use, the control module may also be configured to selectively deactivate.Type: ApplicationFiled: October 14, 2011Publication date: April 12, 2012Applicant: Light Sciences Oncology, Inc.Inventors: James C. Chen, Steven R. Daly, Zihong Guo, Llew Keltner, Jeffrey R. Storm
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Publication number: 20110281837Abstract: 3-substituted-6-aryl pyridines of Formula I are provided: wherein R1, R2, R3, R8, R9, A and Ar are defined herein. Such compounds are ligands of C5a receptors. Preferred compounds of Formula I bind to C5a receptors with high affinity and exhibit neutral antagonist or inverse agonist activity at C5a receptors. The present invention also relates to pharmaceutical compositions comprising such compounds, and to the use of such compounds in treating a variety of inflammatory, cardiovascular, and immune system disorders. In addition, the present invention provides labeled 3-substituted-6-aryl pyridines, which are useful as probes for the localization of C5a receptors.Type: ApplicationFiled: January 3, 2011Publication date: November 17, 2011Inventors: Alan J. Hutchinson, Jun Yuan, Kyungae Lee, George D. Maynard, Bertrand L. Chenard, Nian Liu, Qin Guo, Zihong Guo, Peter Hrnciar
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Patent number: 8057464Abstract: A light transmission system to provide photodynamic treatment to a patient includes a single use integrated control module and catheter assembly having a plurality of light emitting diodes (LEDs) to transmit light toward target cells within a patient. The integrated light catheter and control module are used in combination with a light activated drug. Selected operating parameters may be programmed into the control module, or it may be wirelessly programmable in situ prior to use to allow user flexibility to tailor treatment for a particular patient or condition. Among the features that prevent reuse are that the control module lacks access to recharge the power source, and it may include a deactivation module that destroys circuitry or software when triggered. To prevent patient interference when in use, the control module may also be configured to selectively deactivate.Type: GrantFiled: May 3, 2006Date of Patent: November 15, 2011Assignee: Light Sciences Oncology, Inc.Inventors: James C. Chen, Steven R. Daly, Zihong Guo, Llew Keltner, Jeffrey R. Storm
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Patent number: 8052604Abstract: A combined imaging/HIFU probe includes an imaging scan head, a HIFU transducer, and an outlet port that delivers a flow of fluid across the HIFU transducer. At least a portion of the body cavity is filled with fluid in which the probe is immersed. The fluid provides a coupling for transmission of ultrasound energy between the probe and the patient. A flow of fluid may also be used to flush obstructions from an area of tissue near the HIFU transducer. Further described herein is a cuff to help retain fluid in the body cavity, a regulator to regulate fluid flow with respect to the body cavity according to a desired fluid pressure, and a cover for the HIFU transducer that has at least one perforation defined therethrough to allow fluid to flow through the cover. Further disclosed herein are methods of deploying a combined imaging/HIFU probe in a body cavity.Type: GrantFiled: July 31, 2007Date of Patent: November 8, 2011Assignee: Mirabilis Medica Inc.Inventors: Michael P. H. Lau, Gregory Paul Darlington, Michael J. Connolly, Zihong Guo
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Publication number: 20110155745Abstract: Substantially thermally sealed containers including flexible connectors joining an aperture in the exterior of the container to an aperture in a substantially thermally sealed storage region within the container are described. The flexible connectors include a duct forming an elongated thermal pathway between the exterior of the container and the substantially thermally sealed storage region within the container. The flexible connectors include compression units mated to each end of the duct and a plurality of compression strands connected between the compression units.Type: ApplicationFiled: November 29, 2010Publication date: June 30, 2011Inventors: Fong-Li Chou, Geoffrey F. Deane, William Gates, Zihong Guo, Roderick A. Hyde, Edward K.Y. Jung, Nathan P. Myhrvold, Nels R. Peterson, Clarence T. Tegreene, Charles Whitmer, Lowell L. Wood, JR.
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Publication number: 20110077464Abstract: A method of manufacture and medical apparatus that provides an apparatus useful in illuminating at least a portion of a lumen of a body. The apparatus includes an elongated flexible member and a polymer encasement portion encasing a plurality of light emitters. The light emitters may be electrically coupled to one another without the use of wire bonds, and in some embodiments may be coupled without intervening electrical paths or traces. A maximum cross-sectional dimension of the polymer encasement portion may be less than twice a dimension of one of the light emitters. In some embodiments the maximum cross-sectional dimension is less than or equal to the sum of the dimension of one of the light emitters and a marginal dimension by which an outer portion of the polymer encasement portion extends beyond the light emitter. Light emitters may be arranged linearly, helically or in partially overlapping back-to-back relation.Type: ApplicationFiled: September 24, 2010Publication date: March 31, 2011Applicant: Light Sciences Oncology, Inc.Inventors: Phillip Burwell, James C. Chen, Zihong Guo, Steven R. Daly, David B. Shine, Gary Lichttenegger, Jennifer K. Matson, Jean Bishop, Nick Yeo, Hugh Narciso
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Patent number: RE47491Abstract: A light transmission system to provide photodynamic treatment to a patient includes a single use integrated control module and catheter assembly having a plurality of light emitting diodes (LEDs) to transmit light toward target cells within a patient. The integrated light catheter and control module are used in combination with a light activated drug. Selected operating parameters may be programmed into the control module, or it may be wirelessly programmable in situ prior to use to allow user flexibility to tailor treatment for a particular patient or condition. Among the features that prevent reuse are that the control module lacks access to recharge the power source, and it may include a deactivation module that destroys circuitry or software when triggered. To prevent patient interference when in use, the control module may also be configured to selectively deactivate.Type: GrantFiled: April 1, 2016Date of Patent: July 9, 2019Assignee: LIGHT SCIENCES ONCOLOGY, INC.Inventors: James C. Chen, Steven R. Daly, Zihong Guo, Llew Keltner, Jeffrey R. Storm
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Patent number: D983894Type: GrantFiled: June 2, 2022Date of Patent: April 18, 2023Inventor: Zihong Guo
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Patent number: D983895Type: GrantFiled: June 2, 2022Date of Patent: April 18, 2023Inventor: Zihong Guo
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Patent number: D983896Type: GrantFiled: June 2, 2022Date of Patent: April 18, 2023Inventor: Zihong Guo