Patents by Inventor Zita S. Netzel
Zita S. Netzel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230191097Abstract: A two-part bioactive agent delivery system, the system including a disposable part comprising an agent reservoir, a bolus chamber, the volume of the bolus chamber being less than the volume of the agent reservoir, an agent outlet, and a valve having a first position communicating the agent reservoir with the bolus chamber and a second position communicating the bolus chamber with the outlet; and a reusable part including a valve driver, a power source and control electronics, the control electronics being adapted to control the valve driver to actuate the valve to deliver bioactive agent from the agent reservoir to the agent outlet; the system further having a spring extending between the agent reservoir piston and a surface of the reusable part or of the disposable part to pressurize the agent reservoir when the spring is compressed and the agent reservoir contains a quantity of bioactive agent.Type: ApplicationFiled: July 28, 2022Publication date: June 22, 2023Inventors: Zita S. NETZEL, Gary STACEY, Alexander David NORMAN, Congyi HUANG, Timothy Charles FREARSON, Charles Frazer KILBY, Patrick H. RUANE, Alan J. LEVY, Kevin W. GELSTON, Jennifer DARMOUR, Jenny E. HAPGOOD, David Evans ROTH, Ronald A. OVERBECK, Ling-Kang TONG
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Patent number: 11400266Abstract: A two-part bioactive agent delivery system, the system including a disposable part comprising an agent reservoir, a bolus chamber, the volume of the bolus chamber being less than the volume of the agent reservoir, an agent outlet, and a valve having a first position communicating the agent reservoir with the bolus chamber and a second position communicating the bolus chamber with the outlet; and a reusable part including a valve driver, a power source and control electronics, the control electronics being adapted to control the valve driver to actuate the valve to deliver bioactive agent from the agent reservoir to the agent outlet; the system further having a spring extending between the agent reservoir piston and a surface of the reusable part or of the disposable part to pressurize the agent reservoir when the spring is compressed and the agent reservoir contains a quantity of bioactive agent.Type: GrantFiled: February 25, 2019Date of Patent: August 2, 2022Assignee: Morningside Venture Investments LimitedInventors: Zita S. Netzel, Gary Stacey, Alexander David Norman, Congyi Huang, Timothy Charles Frearson, Charles Frazer Kilby, Patrick H. Ruane, Alan J. Levy, Kevin W. Gelston, Jennifer Darmour, Jenny E. Hapgood, David Evans Roth, Ronald A. Overbeck, Ling-Kang Tong
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Publication number: 20190275308Abstract: A two-part bioactive agent delivery system, the system including a disposable part comprising an agent reservoir, a bolus chamber, the volume of the bolus chamber being less than the volume of the agent reservoir, an agent outlet, and a valve having a first position communicating the agent reservoir with the bolus chamber and a second position communicating the bolus chamber with the outlet; and a reusable part including a valve driver, a power source and control electronics, the control electronics being adapted to control the valve driver to actuate the valve to deliver bioactive agent from the agent reservoir to the agent outlet; the system further having a spring extending between the agent reservoir piston and a surface of the reusable part or of the disposable part to pressurize the agent reservoir when the spring is compressed and the agent reservoir contains a quantity of bioactive agent.Type: ApplicationFiled: February 25, 2019Publication date: September 12, 2019Applicant: Chrono Therapeutics Inc.Inventors: Zita S. NETZEL, Gary STACEY, Alexander David NORMAN, Congyi HUANG, Timothy Charles FREARSON, Charles Frazer KILBY, Patrick H. RUANE, Alan J. LEVY, Kevin W. GELSTON, Jennifer DARMOUR, Jenny E. HAPGOOD, David Evans ROTH, Ronald A. OVERBECK, Ling-Kang TONG
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Patent number: 10232156Abstract: A two-part bioactive agent delivery system, the system including a disposable part comprising an agent reservoir, a bolus chamber, the volume of the bolus chamber being less than the volume of the agent reservoir, an agent outlet, and a valve having a first position communicating the agent reservoir with the bolus chamber and a second position communicating the bolus chamber with the outlet; and a reusable part including a valve driver, a power source and control electronics, the control electronics being adapted to control the valve driver to actuate the valve to deliver bioactive agent from the agent reservoir to the agent outlet; the system further having a spring extending between the agent reservoir piston and a surface of the reusable part or of the disposable part to pressurize the agent reservoir when the spring is compressed and the agent reservoir contains a quantity of bioactive agent.Type: GrantFiled: September 8, 2017Date of Patent: March 19, 2019Assignee: Chrono Therapeutics Inc.Inventors: Zita S. Netzel, Gary Stacey, Alexander David Norman, Congyi Huang, Timothy Charles Frearson, Charles Frazer Kilby, Patrick H. Ruane, Alan J. Levy, Kevin W. Gelston, Jennifer Darmour, Jenny E. Hapgood, David Evans Roth, Ronald A. Overbeck, Ling-Kang Tong
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Patent number: 10213586Abstract: A two-part bioactive agent delivery system, the system including a disposable part comprising an agent reservoir, a bolus chamber, the volume of the bolus chamber being less than the volume of the agent reservoir, an agent outlet, and a valve having a first position communicating the agent reservoir with the bolus chamber and a second position communicating the bolus chamber with the outlet; and a reusable part including a valve driver, a power source and control electronics, the control electronics being adapted to control the valve driver to actuate the valve to deliver bioactive agent from the agent reservoir to the agent outlet; the system further having a spring extending between the agent reservoir piston and a surface of the reusable part or of the disposable part to pressurize the agent reservoir when the spring is compressed and the agent reservoir contains a quantity of bioactive agent.Type: GrantFiled: January 28, 2016Date of Patent: February 26, 2019Assignee: Chrono Therapeutics Inc.Inventors: Zita S. Netzel, Gary Stacey, Alexander David Norman, Congyi Huang, Timothy Charles Frearson, Charles Frazer Kilby, Patrick H. Ruane, Alan J. Levy, Kevin W. Gelston, Jennifer Darmour, Jenny E. Hapgood, David Evans Roth, Ronald A. Overbeck, Ling-Kang Tong
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Publication number: 20180117291Abstract: A two-part bioactive agent delivery system, the system including a disposable part comprising an agent reservoir, a bolus chamber, the volume of the bolus chamber being less than the volume of the agent reservoir, an agent outlet, and a valve having a first position communicating the agent reservoir with the bolus chamber and a second position communicating the bolus chamber with the outlet; and a reusable part including a valve driver, a power source and control electronics, the control electronics being adapted to control the valve driver to actuate the valve to deliver bioactive agent from the agent reservoir to the agent outlet; the system further having a spring extending between the agent reservoir piston and a surface of the reusable part or of the disposable part to pressurize the agent reservoir when the spring is compressed and the agent reservoir contains a quantity of bioactive agent.Type: ApplicationFiled: September 8, 2017Publication date: May 3, 2018Inventors: Zita S. NETZEL, Gary STACEY, Alexander David NORMAN, Congyi HUANG, Timothy Charles FREARSON, Charles Frazer KILBY, Patrick H. RUANE, Alan J. LEVY, Kevin W. GELSTON, Jennifer DARMOUR, Jenny E. HAPGOOD, David Evans ROTH, Ronald A. OVERBECK, Ling-Kang TONG
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Publication number: 20170239468Abstract: A switch-operated therapeutic agent delivery device. Embodiments of the operated therapeutic agent delivery device my include a switch that can be operated by a user, a device controller connected to the switch through a switch input where the device can actuate the device when certain predetermined conditions are met, following performance of both a digital switch validation test and an analog switch validation test. The switch operated therapeutic agent delivery device may have two parts, which are assembled by a user prior to use. These devices may be configured to determine if a current is present between the anode and cathode when drug is not intended to be delivered by the device. These devices may indirectly control and/or monitor the applied current without directly measuring from the cathode of the patient terminal.Type: ApplicationFiled: May 8, 2017Publication date: August 24, 2017Inventors: John LEMKE, Scot SATRE, Corinna X. CHEN, Brian W. READ, Zita S. NETZEL, David SEWARD, Bradley E. WHITE, Paul HAYTER, Jason E. DOUGHERTY
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Publication number: 20160296750Abstract: A switch operated therapeutic agent delivery device is described. The device comprises two parts, which are assembled by a user prior to use. A first part contains a power supply and circuitry for the device; and a second part comprises electrodes and reservoirs containing the therapeutic agent to be delivered. The action of combining the two parts of the device causes the two parts to be irreversibly coupled together, completes an electrical connection between the two parts, and closes one or more switches, thereby connecting a power source, such as a battery, into the device's circuitry, thereby powering the device on so that it is ready for use. The device can then be attached to a patient, who can operate the device by pressing a button in a proper sequence.Type: ApplicationFiled: June 13, 2016Publication date: October 13, 2016Inventors: Zita S. NETZEL, John LEMKE, David SEWARD, Brian W. READ, Bradley E. WHITE, Corinna X. CHEN, Paul HAYTER
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Publication number: 20160220798Abstract: A two-part bioactive agent delivery system, the system including a disposable part comprising an agent reservoir, a bolus chamber, the volume of the bolus chamber being less than the volume of the agent reservoir, an agent outlet, and a valve having a first position communicating the agent reservoir with the bolus chamber and a second position communicating the bolus chamber with the outlet; and a reusable part including a valve driver, a power source and control electronics, the control electronics being adapted to control the valve driver to actuate the valve to deliver bioactive agent from the agent reservoir to the agent outlet; the system further having a spring extending between the agent reservoir piston and a surface of the reusable part or of the disposable part to pressurize the agent reservoir when the spring is compressed and the agent reservoir contains a quantity of bioactive agent.Type: ApplicationFiled: January 28, 2016Publication date: August 4, 2016Inventors: Zita S. NETZEL, Gary STACEY, Alexander David NORMAN, Congyi HUANG, Timothy Charles FREARSON, Charles Frazer KILBY, Patrick H. RUANE, Alan J. LEVY, Kevin W. GELSTON, Jennifer DARMOUR, Jenny E. HAPGOOD, David Evans ROTH, Ronald A. OVERBECK, Ling-Kang TONG
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Patent number: 9364656Abstract: A switch operated therapeutic agent delivery device is described. The device comprises two parts, which are assembled by a user prior to use. A first part contains a power supply and circuitry for the device; and a second part comprises electrodes and reservoirs containing the therapeutic agent to be delivered. The action of combining the two parts of the device causes the two parts to be irreversibly coupled together, completes an electrical connection between the two parts, and closes one or more switches, thereby connecting a power source, such as a battery, into the device's circuitry, thereby powering the device on so that it is ready for use. The device can then be attached to a patient, who can operate the device by pressing a button in a proper sequence.Type: GrantFiled: March 9, 2012Date of Patent: June 14, 2016Assignees: Incline Therapeutics, Inc., Alza CorporationInventors: Zita S. Netzel, John Lemke, David Seward, Brian W. Read, Bradley E. White, Corinna X. Chen, Paul Hayter
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Publication number: 20140115882Abstract: A switch operated therapeutic agent delivery device is described. The device comprises two parts, which are assembled by a user prior to use. A first part contains a power supply and circuitry for the device; and a second part comprises electrodes and reservoirs containing the therapeutic agent to be delivered. The action of combining the two parts of the device causes the two parts to be irreversibly coupled together, completes an electrical connection between the two parts, and closes one or more switches, thereby connecting a power source, such as a battery, into the device's circuitry, thereby powering the device on so that it is ready for use. The device can then be attached to a patient, who can operate the device by pressing a button in a proper sequence.Type: ApplicationFiled: March 9, 2012Publication date: May 1, 2014Inventors: Zita S. Netzel, John Lemke, David Seward, Brian W. Read, Bradley E. White, Corinna X. Chen, Paul Hayter
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Patent number: 8301238Abstract: A switch operated therapeutic agent delivery device is described. The device comprises two parts, which are assembled by a user prior to use. A first part contains a power supply and circuitry for the device; and a second part comprises electrodes and reservoirs containing the therapeutic agent to be delivered. The action of combining the two parts of the device causes the two parts to be irreversibly coupled together, completes an electrical connection between the two parts, and closes one or more switches, thereby connecting a power source, such as a battery, into the device's circuitry, thereby powering the device on so that it is ready for use. The device can then be attached to a patient, who can operate the device by pressing a button in a proper sequence.Type: GrantFiled: September 30, 2011Date of Patent: October 30, 2012Assignees: Incline Therapeutics, Inc., Alza CorporationInventors: Zita S. Netzel, John Lemke, David Seward, Brian W. Read, Bradley E. White, Corinna X. Chen, Paul Hayter
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Publication number: 20120253263Abstract: A switch operated therapeutic agent delivery device is described. The device comprises two parts, which are assembled by a user prior to use. A first part contains a power supply and circuitry for the device; and a second part comprises electrodes and reservoirs containing the therapeutic agent to be delivered. The action of combining the two parts of the device causes the two parts to be irreversibly coupled together, completes an electrical connection between the two parts, and closes one or more switches, thereby connecting a power source, such as a battery, into the device's circuitry, thereby powering the device on so that it is ready for use. The device can then be attached to a patient, who can operate the device by pressing a button in a proper sequence.Type: ApplicationFiled: September 30, 2011Publication date: October 4, 2012Inventors: Zita S. Netzel, John Lemke, David Seward, Brian W. Read, Bradley E. White, Corinna X. Chen, Paul Hayter
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Patent number: D699855Type: GrantFiled: November 12, 2012Date of Patent: February 18, 2014Assignee: Incline Therapeutics, Inc.Inventors: Zita S. Netzel, Michael D. Nelson, David Seward