Patents by Inventor Zong-Keng KUO

Zong-Keng KUO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240165181
    Abstract: A composition for inhibiting intestinal permeability, treating leaky gut related diseases and/or preventing leaky gut related diseases including a Chinese herbal compound material or a Chinese herbal compound extract is provided. The Chinese herbal compound material includes Ganoderma, red jujube, longan and lotus seed. Moreover, the Chinese herbal compound extract includes a Ganoderma extract, a red jujube extract, a longan extract and a lotus seed extract.
    Type: Application
    Filed: June 1, 2023
    Publication date: May 23, 2024
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: I-Hong PAN, Kuei-Chang LI, Zong-Keng KUO, Chu-Hsun LU, Yen-Wu HSIEH, Shu-Fang WEN
  • Patent number: 11701399
    Abstract: A composition for modulating intestinal permeability and/or treating and/or preventing leaky gut related diseases including a Chinese herbal compound material or a Chinese herbal compound extract is provided. The Chinese herbal compound material includes Ganoderma, red jujube, longan and lotus seed. Moreover, the Chinese herbal compound extract includes a Ganoderma extract, a red jujube extract, a longan extract and a lotus seed extract.
    Type: Grant
    Filed: December 30, 2020
    Date of Patent: July 18, 2023
    Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: I-Hong Pan, Kuei-Chang Li, Zong-Keng Kuo, Chu-Hsun Lu, Yen-Wu Hsieh, Shu-Fang Wen
  • Publication number: 20220249395
    Abstract: A method for treating an autoimmune neurological disease and/or a neurodegenerative disease is provided. The method includes administering an effective amount of at least one compound having Formula (I), Formula (II) or Formula (III), or its geometric isomer, enantiomer or diastereomer to a subject in need thereof: wherein is a single or double bond, X is NCH3 or CH2, Y is null, O or N, Z is O or N, R1 is H, OH, and R2 is null, H, C1-C8 alkyl, —(C?O)-alkyl, —(C?O)-aryl, —(C?O)-alkyl-aryl, —(C?O)-heteroaryl, cycloalkyl or heterocycloalkyl, which optionally substituted by one or more of —OH, —NO2, —NH2, —NR3R4, carbonyl, alkoxyl, alkyl or —OCF3, wherein R3 and R4 independently are H, alkyl, O2CH3, —(C?O)—CH3 or (C?O)—NH2.
    Type: Application
    Filed: April 22, 2022
    Publication date: August 11, 2022
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Kuo-Kuei HUANG, I-Hong PAN, Shu-Fang WEN, Meng-Nan LIN, I-Huang LU, Zong-Keng KUO, Chu-Hsun LU, Tze-Chung LEE, Ya-Yan YANG, Jia-Horng LIAW, Pei-Hsin LIN
  • Patent number: 11400054
    Abstract: A method for treating an autoimmune neurological disease and/or a neurodegenerative disease is provided. The method includes administering an effective amount of at least one compound having Formula (I), Formula (II) or Formula (III), or its geometric isomer, enantiomer or diastereomer to a subject in need thereof: wherein is a single or double bond, X is NCH3 or CH2, Y is null, O or N, Z is O or N, R1 is H, OH, and R2 is null, H, C1-C8 alkyl, —(C?O)-alkyl, —(C?O)-aryl, —(C?O)-alkyl-aryl, —(C?O)-heteroaryl, cycloalkyl or heterocycloalkyl, which optionally substituted by one or more of —OH, —NO2, —NH2, —NR3R4, carbonyl, alkoxyl, alkyl or —OCF3, wherein R3 and R4 independently are H, alkyl, —SO2CH3, —(C?O)—CH3 or —(C?O)—NH2.
    Type: Grant
    Filed: June 29, 2018
    Date of Patent: August 2, 2022
    Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Kuo-Kuei Huang, I-Hong Pan, Shu-Fang Wen, Meng-Nan Lin, I-Huang Lu, Zong-Keng Kuo, Chu-Hsun Lu, Tze-Chung Lee, Ya-Yan Yang, Jia-Horng Liaw, Pei-Hsin Lin
  • Publication number: 20210290710
    Abstract: A composition for modulating intestinal permeability and/or treating and/or preventing leaky gut related diseases including a Chinese herbal compound material or a Chinese herbal compound extract is provided. The Chinese herbal compound material includes Ganoderma, red jujube, longan and lotus seed. Moreover, the Chinese herbal compound extract includes a Ganoderma extract, a red jujube extract, a longan extract and a lotus seed extract.
    Type: Application
    Filed: December 30, 2020
    Publication date: September 23, 2021
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: I-Hong PAN, Kuei-Chang LI, Zong-Keng KUO, Chu-Hsun LU, Yen-Wu HSIEH, Shu-Fang WEN
  • Publication number: 20210015882
    Abstract: The present disclosure provides a pharmaceutical composition for treating or alleviating an autoimmune disease and/or complication thereof and/or nephritis, including: an effective amount of an extract of a plant belonging to Rutaceae as an effective ingredient for treating or alleviating the autoimmune disease and/or complication thereof and/or nephritis, wherein the autoimmune disease is selected from a group consisting of lupus erythematosus, psoriasis, psoriatic arthritis, ankylosing spondylitis, rheumatoid arthritis, juvenile idiopathic arthritis, Crohn's disease and ulcerative colitis (UC).
    Type: Application
    Filed: September 29, 2020
    Publication date: January 21, 2021
    Applicant: Industrial Technology Research Institute
    Inventors: Kuo-Kuei HUANG, I-Horng PAN, Ying-Fei TSAI, I-Huang LU, Chu-Hsun LU, Shu-Fang WEN, Zong-Keng KUO, Shu-Jiau CHIOU
  • Patent number: 10821148
    Abstract: The present disclosure provides a pharmaceutical composition for treating or alleviating an autoimmune disease and/or complication thereof and/or nephritis, including: an effective amount of an extract of a plant belonging to Rutaceae as an effective ingredient for treating or alleviating the autoimmune disease and/or complication thereof and/or nephritis, wherein the autoimmune disease is selected from a group consisting of lupus erythematosus, psoriasis, psoriatic arthritis, ankylosing spondylitis, rheumatoid arthritis, juvenile idiopathic arthritis, Crohn's disease and ulcerative colitis (UC).
    Type: Grant
    Filed: January 26, 2017
    Date of Patent: November 3, 2020
    Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Kuo-Kuei Huang, I-Horng Pan, Ying-Fei Tsai, I-Huang Lu, Chu-Hsun Lu, Shu-Fang Wen, Zong-Keng Kuo, Shu-Jiau Chiou
  • Publication number: 20190000776
    Abstract: A method for treating an autoimmune neurological disease and/or a neurodegenerative disease is provided. The method includes administering an effective amount of at least one compound having Formula (I), Formula (II) or Formula (III), or its geometric isomer, enantiomer or diastereomer to a subject in need thereof: wherein is a single or double bond, X is NCH3 or CH2, Y is null, O or N, R1 is H, OH, and R2 is null, H, C1-C8 alkyl, —(C?O)-alkyl, —(C?O)-aryl, —(C?O)-alkyl-aryl, —(C?O)-heteroaryl, cycloalkyl or heterocycloalkyl, which optionally substituted by one or more of —OH, —NO2, —NH2, —NR3R4, carbonyl, alkoxyl, alkyl or —OCF3, wherein R3 and R4 independently are H, alkyl, —SO2CH3, —(C?O)—CH3 or —(C?O)—NH2.
    Type: Application
    Filed: June 29, 2018
    Publication date: January 3, 2019
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Kuo-Kuei HUANG, I-Hong PAN, Shu-Fang WEN, Meng-Nan LIN, I-Huang LU, Zong-Keng KUO, Chu-Hsun LU, Tze-Chung LEE, Ya-Yan YANG, Jia-Horng LIAW
  • Publication number: 20170258865
    Abstract: The present disclosure provides a pharmaceutical composition for treating or alleviating an autoimmune disease and/or complication thereof and/or nephritis, including: an effective amount of an extract of a plant belonging to Rutaceae as an effective ingredient for treating or alleviating the autoimmune disease and/or complication thereof and/or nephritis, wherein the autoimmune disease is selected from a group consisting of lupus erythematosus, psoriasis, psoriatic arthritis, ankylosing spondylitis, rheumatoid arthritis, juvenile idiopathic arthritis, Crohn's disease and ulcerative colitis (UC).
    Type: Application
    Filed: January 26, 2017
    Publication date: September 14, 2017
    Applicant: Industrial Technology Research Institute
    Inventors: Kuo-Kuei HUANG, I-Horng PAN, Ying-Fei TSAI, I-Huang LU, Chu-Hsun LU, Shu-Fang WEN, Zong-Keng KUO, Shu-Jiau CHIOU
  • Patent number: 9682062
    Abstract: The disclosure provides a pharmaceutical composition for inhibiting angiogenesis, including an effective amount of an extract of Juniperus chinensis or an effective amount of a lignan as an effective ingredient. The pharmaceutical composition may further include a pharmaceutically acceptable carrier or salt. The disclosure also provides a method for inhibiting angiogenesis, including administering an effective amount of an extract of Juniperus chinensis or an effective amount of a lignan as an effective ingredient for inhibiting angiogenesis to a subject in need thereof.
    Type: Grant
    Filed: December 18, 2013
    Date of Patent: June 20, 2017
    Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: I-Horng Pan, Hsin-Jan Yao, Mei-Wei Lin, I-Huang Lu, Hsin-Chieh Wu, Hsiang-Wen Tseng, Ching-Huai Ko, Chun-Chung Wang, Zong-Keng Kuo, Shyh-Horng Lin, Yi-Cheng Cheng, Tien-Soung Tong
  • Patent number: 9289443
    Abstract: A pharmaceutical composition for preventing or treating hepatitis C is provided, including oleanolic acid derivatives as an active ingredient and a pharmaceutically acceptable carrier. A method for preventing or treating hepatitis C in a subject in need thereof is also provided by administering the subject the pharmaceutical composition given above.
    Type: Grant
    Filed: October 26, 2011
    Date of Patent: March 22, 2016
    Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Lain-Tze Lee, Shau-Feng Chang, Zong-Keng Kuo, Hui-Ping Tsai
  • Publication number: 20160008319
    Abstract: The disclosure provides a pharmaceutical composition for inhibiting angiogenesis, including an effective amount of a lignan as an effective ingredient. The pharmaceutical composition may further include a pharmaceutically acceptable carrier or salt. The disclosure also provides a method for inhibiting angiogenesis, including administering an effective amount of a lignan as an effective ingredient for inhibiting angiogenesis to a subject in need thereof.
    Type: Application
    Filed: September 24, 2015
    Publication date: January 14, 2016
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: I-Horng PAN, Hsin-Jan YAO, Mei-Wei LIN, I-Huang LU, Hsin-Chieh WU, Hsiang-Wen TSENG, Ching-Huai KO, Chun-Chung WANG, Zong-Keng KUO, Shyh-Horng LIN, Yi-Cheng CHENG, Tien-Soung TONG
  • Patent number: 8802662
    Abstract: The invention provides an anti-hepatitis C composition including: an effective amount of limonoid compound, wherein the structure of the limonoid compound is shown as Structure (I): where R1 comprises H or OAc and R2 comprises H or COCH(CH3)2; and a pharmaceutically acceptable carrier or salt, and the anti-hepatitis C composition is used for inhibiting hepatitis C virus or treating hepatitis C. The invention also provides a method for treating hepatitis C and a method for preparing a drug for inhibiting hepatitis C viruses or treating hepatitis C.
    Type: Grant
    Filed: October 4, 2009
    Date of Patent: August 12, 2014
    Assignee: Industrial Technology Research Institute
    Inventors: Lain-Tze Lee, Shau-Feng Chang, Hui-Ping Tsai, Zong-Keng Kuo, Chen-Fang Chung
  • Publication number: 20140170250
    Abstract: The disclosure provides a pharmaceutical composition for inhibiting angiogenesis, including an effective amount of an extract of Juniperus chinensis or an effective amount of a lignan as an effective ingredient. The pharmaceutical composition may further include a pharmaceutically acceptable carrier or salt. The disclosure also provides a method for inhibiting angiogenesis, including administering an effective amount of an extract of Juniperus chinensis or an effective amount of a lignan as an effective ingredient for inhibiting angiogenesis to a subject in need thereof.
    Type: Application
    Filed: December 18, 2013
    Publication date: June 19, 2014
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: I-Horng PAN, Hsin-Jan YAO, Mei-Wei LIN, I-Huang LU, Hsin-Chieh WU, Hsiang-Wen TSENG, Ching-Huai KO, Chun-Chung WANG, Zong-Keng KUO, Shyh-Horng LIN, Yi-Cheng CHENG, Tien-Soung TONG
  • Publication number: 20120165279
    Abstract: A pharmaceutical composition for preventing or treating hepatitis C is provided, including oleanolic acid derivatives as an active ingredient and a pharmaceutically acceptable carrier. A method for preventing or treating hepatitis C in a subject in need thereof is also provided by administering the subject the pharmaceutical composition given above.
    Type: Application
    Filed: October 26, 2011
    Publication date: June 28, 2012
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Lain-Tze Lee, Shau-Feng Chang, Zong-Keng Kuo, Hui-Ping Tsai
  • Publication number: 20100317637
    Abstract: The invention provides an anti-hepatitis C composition including: an effective amount of limonoid compound, wherein the structure of the limonoid compound is shown as Structure (I): where R1 comprises H or OAc and R2 comprises H or COCH(CH3)2; and a pharmaceutically acceptable carrier or salt, and the anti-hepatitis C composition is used for inhibiting hepatitis C virus or treating hepatitis C. The invention also provides a method for treating hepatitis C and a method for preparing a drug for inhibiting hepatitis C viruses or treating hepatitis C.
    Type: Application
    Filed: October 4, 2009
    Publication date: December 16, 2010
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Lain-Tze LEE, Shau-Feng CHANG, Hui-Ping TSAI, Zong-Keng KUO, Chen-Fang CHUNG