Patents by Inventor Zonggen Peng

Zonggen Peng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Phenylmethyl-piperazine derivatives and antiviral uses thereof
    Patent number: 11939307
    Abstract: Disclosed are a benzyl piperazine compound, a preparation method there for and an application thereof in an antivirus. The benzyl piperazine compound has a structure represented by the following general formula(I). It is proven by experiments that the benzyl piperazine compound not only has significant antiviral activity, but also has the advantages of low cytotoxicity, a high selectivity index and soon.
    Type: Grant
    Filed: November 29, 2019
    Date of Patent: March 26, 2024
    Assignee: INSTITUTE OF MEDICINAL BIOTECHNOLOGY, CHINESE ACADEMY OF MEDICAL SCIENCES
    Inventors: Yanping Li, Zhuorong Li, Zonggen Peng, Xinbei Jiang, Yixuan Wang, Jianrui Li, Jiali Tan
  • BENZYL PIPERAZINE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF IN ANTIVIRUS
    Publication number: 20230024612
    Abstract: Disclosed are a benzyl piperazine compound, a preparation method there for and an application thereof in an antivirus. The benzyl piperazine compound has a structure represented by the following general formula(I). It is proven by experiments that the benzyl piperazine compound not only has significant antiviral activity, but also has the advantages of low cytotoxicity, a high selectivity index and soon.
    Type: Application
    Filed: November 29, 2019
    Publication date: January 26, 2023
    Inventors: Yanping LI, Zhuorong LI, Zonggen PENG, Xinbei JIANG, Yixuan WANG, Jianrui LI, Jiali TAN
  • Type of antiviral compound
    Patent number: 10252987
    Abstract: Provided are a new aromatic cyanogen compound and a preparation method thereof. The present invention also relates to the use of such compound in antiviral drugs, in particular the use thereof in anti-HCV drugs.
    Type: Grant
    Filed: August 17, 2016
    Date of Patent: April 9, 2019
    Assignee: Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences
    Inventors: Yanping Li, Zhuorong Li, Zonggen Peng, Jianrui Li, Xinbei Jiang, Jinhua Chen, Jiandong Jiang
  • NEW TYPE OF ANTIVIRAL COMPOUND
    Publication number: 20180208549
    Abstract: Provided are a new aromatic cyanogen compound and a preparation method thereof. The present invention also relates to the use of such compound in antiviral drugs, in particular the use thereof in anti-HCV drugs.
    Type: Application
    Filed: August 17, 2016
    Publication date: July 26, 2018
    Inventors: Yanping Li, Zhuorong Li, Zonggen Peng, Jianrui Li, Xinbei Jiang, Jinhua Chen, Jiandong Jiang
  • Phenanthridine derivatives, preparation methods and uses thereof
    Patent number: 9682954
    Abstract: The present invention relates to the pharmaceutical field, in particular to a phenanthridine derivative as shown in general formula (1) a pharmaceutical composition comprising the derivative, its preparation method, and its uses in manufacture of a medicament for the prevention or treatment of a disease related to the activity of Wnt signaling pathway, hepatitis C and hepatitis B.
    Type: Grant
    Filed: February 28, 2014
    Date of Patent: June 20, 2017
    Assignees: Kunming Institute of Botany, The Chinese Academy of Sciences, Shanghai Institutes for Biological Sciences, CAS, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences
    Inventors: Xiaojiang Hao, Duozhi Chen, Lin Li, Zonggen Peng, Jiandong Jiang, Yingtong Di, Junlin Yin, Sheng Wang, Jieyun Cai
  • Phenanthridine Derivatives, Preparation Methods and Uses Thereof
    Publication number: 20160083364
    Abstract: The present invention relates to the pharmaceutical field, in particular to a phenanthridine derivative as shown in general formula (1) a pharmaceutical composition comprising the derivative, its preparation method, and its uses in manufacture of a medicament for the prevention or treatment of a disease related to the activity of Wnt signaling pathway, hepatitis C and hepatitis B.
    Type: Application
    Filed: February 28, 2014
    Publication date: March 24, 2016
    Inventors: Xiaojiang Hao, Duozhi Chen, Lin Li, Zonggen Peng, Jiandong Jiang, Yingtong Di, Junlin Yin, Sheng Wang, Jieyun Cai
  • MATRINIC ACID/MATRINE DERIVATIVES AND PREPARATION METHODS AND USES THEREOF
    Publication number: 20130190345
    Abstract: The present invention relates to a N-substituted matrinic acid derivative or matrine derivative, and its preparation method and uses. Specifically, the present invention relates to a compound of Formula (I) or (II) (wherein all the definitions of substituted groups are those mentioned in the specification), or a pharmaceutically acceptable salt, geometric isomer, stereoisomer, solvate, ester or prodrug thereof. The present invention further relates to a method for preparing the compound of the present invention, a pharmaceutical composition containing the compound, and uses thereof in manufacture of a medicament. The compound of the present invention can be used for prophylaxis and/or treatment of a disease or disorder associated with viral infection such as hepatitis B and/orhepatitis C and/or AIDS.
    Type: Application
    Filed: April 29, 2011
    Publication date: July 25, 2013
    Applicants: CSPC Zongqi Pharmaceutical Technology (Shijiahuang) Co., Ltd., Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences
    Inventors: Jiandong Jiang, Danqing Song, Nana Du, Zonggen Peng, Yuping Wang, Limei Gao, Yanxing Han, Xin Li, Chunxin Li
  • Set of Geldanamycin Derivatives and Their Preparation Methods
    Publication number: 20100311694
    Abstract: A set of geldanamycin derivatives and their preparation methods. Pharmaceutical compositions comprising the said compounds as an active ingredient which are used as antivirus and antitumor agents. The said derivatives are used in the manufacture of heat shock protein 90 (Hsp 90) inhibiting agents which have the utility as antivirus and antitumor agents.
    Type: Application
    Filed: January 19, 2009
    Publication date: December 9, 2010
    Applicant: Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences
    Inventors: Zhuorong Li, Zonggen Peng, Yanping Li, Jianhua Zhu, Peizhen Tao, Bo Fan, Yuping Wang, Guangzhi Shan, Shuqin Wang, Tian Zhang, Jiandong Jiang