Patents by Inventor Zuodong Ye

Zuodong Ye has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of promoting antitumor or anti-cancer immunity
    Patent number: 11986482
    Abstract: Methods of inhibiting endosomal trafficking of PD-L1, inducing PD-L1 secretion via exosomes, decreasing PD-L1 level at a surface of a cancer or tumor cell, and treating a cancer or tumor through promoting T cell immune response in a subject suffering from a cancer or tumor, includes the step of administering a compound of Formula I to various cells. Also, a composition to treat a cancer or a tumor, includes a compound of Formula I and an anti-PD-1 antibody.
    Type: Grant
    Filed: March 21, 2022
    Date of Patent: May 21, 2024
    Assignees: City University of Hong Kong, 6J Biotechnology (Hong Kong) Limited
    Inventors: Jianbo Yue, Qingru Zhang, Zuodong Ye, Wang Peng
  • Method of treating metastatic cancer in a subject with a protein inhibitor
    Patent number: 11484536
    Abstract: A method of treating metastatic cancer in a subject in need thereof including administering an effective amount of a capping protein Z inhibitor to the subject. A method of inhibiting metastasis of cancer cells including administering an effective amount of a capping protein Z inhibitor.
    Type: Grant
    Filed: July 24, 2020
    Date of Patent: November 1, 2022
    Assignees: City University of Hong Kong, 6J Biotechnology Limited
    Inventors: Jianbo Yue, Qingru Zhang, Zuodong Ye, Dawei Wang, Kaiyuan Zhu
  • METHOD OF PROMOTING ANTITUMOR OR ANTI-CANCER IMMUNITY
    Publication number: 20220305022
    Abstract: Methods of inhibiting endosomal trafficking of PD-L1, inducing PD-L1 secretion via exosomes, decreasing PD-L1 level at a surface of a cancer or tumor cell, and treating a cancer or tumor through promoting T cell immune response in a subject suffering from a cancer or tumor, includes the step of administering a compound of Formula I to various cells. Also, a composition to treat a cancer or a tumor, includes a compound of Formula I and an anti-PD-1 antibody.
    Type: Application
    Filed: March 21, 2022
    Publication date: September 29, 2022
    Inventors: JIANBO YUE, QINGRU ZHANG, ZUODONG YE, WANG PENG
  • METHOD OF TREATING METASTATIC CANCER IN A SUBJECT WITH A PROTEIN INHIBITOR
    Publication number: 20220023307
    Abstract: A method of treating metastatic cancer in a subject in need thereof including administering an effective amount of a capping protein Z inhibitor to the subject. A method of inhibiting metastasis of cancer cells including administering an effective amount of a capping protein Z inhibitor.
    Type: Application
    Filed: July 24, 2020
    Publication date: January 27, 2022
    Inventors: Jianbo Yue, Qingru Zhang, Zuodong Ye, Dawei Wang, Kaiyuan Zhu