Patents by Inventor Zuzana Zachar

Zuzana Zachar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • THERAPEUTIC METHODS AND COMPOSITIONS FOR TREATING CANCER USING 6,8-BIS-BENZYLTHIO-OCTANOIC ACID AND AN AUTOPHAGY INHIBITOR
    Publication number: 20220054445
    Abstract: The invention provides methods and compositions for treating cancer by administering to a patient in need thereof a therapeutically effective amount of 6,8-bis-benzylthio-octanoic acid and an autophagy inhibitor.
    Type: Application
    Filed: December 20, 2019
    Publication date: February 24, 2022
    Inventors: Timothy S. Pardee, Sanjeev Luther, Paul Bingham, Zuzana Zachar, Shawn D. Stuart, Robert G.L. Shorr, Tamotsu Takeuchi, Yusuke Kito, Chiemi Saigo
  • THERAPEUTIC METHODS AND COMPOSITIONS FOR TREATING PROSTATE CANCER USING 6,8-BIS-BENZYLTHIO-OCTANOIC ACID
    Publication number: 20210000778
    Abstract: The invention provides methods, compositions, and medical kits for treating prostate cancer using 6,8-bis-benzylthio-octanoic acid or a pharmaceutically acceptable salt thereof, including combination therapy with docetaxel.
    Type: Application
    Filed: April 16, 2019
    Publication date: January 7, 2021
    Inventors: Sanjeev Luther, Robert G.L. Shorr, Paul Bingham, Zuzana Zachar
  • Lipoic acid derivatives
    Patent number: 9150509
    Abstract: Lipoic acid derivatives and pharmaceutical formulations containing lipoic acid derivatives are useful in the treatment and prevention of disease characterized by disease cells that are sensitive to lipoic acid derivatives.
    Type: Grant
    Filed: June 25, 2014
    Date of Patent: October 6, 2015
    Assignee: Cornerstone Pharmaceuticals, Inc.
    Inventors: Paul Bingham, Tom Kwok, Zuzana Zachar
  • LIPOIC ACID DERIVATIVES
    Publication number: 20140364502
    Abstract: Lipoic acid derivatives and pharmaceutical formulations containing lipoic acid derivatives are useful in the treatment and prevention of disease characterized by disease cells that are sensitive to lipoic acid derivatives.
    Type: Application
    Filed: June 25, 2014
    Publication date: December 11, 2014
    Inventors: Paul Bingham, Tom Kwok, Zuzana Zachar
  • Lipoic acid derivatives
    Patent number: 8785475
    Abstract: Lipoic acid derivatives and pharmaceutical formulations containing lipoic acid derivatives are useful in the treatment and prevention of disease characterized by disease cells that are sensitive to lipoic acid derivatives.
    Type: Grant
    Filed: April 17, 2008
    Date of Patent: July 22, 2014
    Assignee: Cornerstone Pharmaceuticals, Inc.
    Inventors: Paul Bingham, Tom Kwok, Zuzana Zachar
  • LIPOIC ACID DERIVATIVES
    Publication number: 20080262034
    Abstract: Lipoic acid derivatives and pharmaceutical formulations containing lipoic acid derivatives are useful in the treatment and prevention of disease characterized by disease cells that are sensitive to lipoic acid derivatives.
    Type: Application
    Filed: April 17, 2008
    Publication date: October 23, 2008
    Inventors: PAUL BINGHAM, TOM KWOK, ZUZANA ZACHAR
  • Lipoic acid derivatives and their use in treatment of disease
    Patent number: 6951887
    Abstract: This invention relates to the identification of a novel class of therapeutic agents which selectively target and kill tumor cells and certain other types of diseased cells, and to compositions comprising lipoic acid derivatives which poison the pyruvate dehydrogenase complex specifically in such cells. This invention also provides for methods of using therapeutically effective amounts of the lipoic acid derivatives for the treatment of cancer and other diseases. The lipoic acid derivatives described herein have a wide range of preventive and therapeutic applications.
    Type: Grant
    Filed: September 24, 2001
    Date of Patent: October 4, 2005
    Assignee: The Research Foundation of State University of New York
    Inventors: Paul M. Bingham, Zuzana Zachar
  • Lipoic acid derivatives and their use in treatment of disease
    Publication number: 20020107234
    Abstract: This invention relates to the identification of a novel class of therapeutic agents which selectively target and kill tumor cells and certain other types of diseased cells, and to compositions comprising lipoic acid derivatives which poison the pyruvate dehydrogenase complex specifically in such cells. This invention also provides for methods of using therapeutically effective amounts of the lipoic acid derivatives for the treatment of cancer and other diseases. The lipoic acid derivatives described herein have a wide range of preventive and therapeutic applications.
    Type: Application
    Filed: September 24, 2001
    Publication date: August 8, 2002
    Inventors: Paul M. Bingham, Zuzana Zachar
  • Lipoic acid derivatives and their use in treatment of disease
    Patent number: 6331559
    Abstract: This invention relates to the identification of a novel class of therapeutic agents which selectively target and kill tumor cells and certain other types of diseased cells, and to compositions comprising lipoic acid derivatives which poison the pyruvate dehydrogenase complex specifically in such cells. This invention also provides for methods of using therapeutically effective amounts of the lipoic acid derivatives for the treatment of cancer and other diseases. The lipoic acid derivatives described herein have a wide range of preventive and therapeutic applications.
    Type: Grant
    Filed: October 26, 1999
    Date of Patent: December 18, 2001
    Assignee: The Research Foundation of State University of New York at Stony Brook
    Inventors: Paul M. Bingham, Zuzana Zachar