Absorbent article having a dehydration indicator

A wearable article comprising a dehydration indicator adapted to measure a urine ionic strength correlated to a specific gravity of the wearer's urine and provide a visible signal when the urine ionic strength reaches a value corresponding to a predetermined threshold of the specific gravity. The wearable article may be a disposable absorbent article. The dehydration indicator may also be comprised in an insert for use with a wearable article. The dehydration indicator may provide qualitative or quantitative information about the ionic strength of the wearer's urine.

Skip to: Description  ·  Claims  ·  References Cited  · Patent History  ·  Patent History
Description
CROSS REFERENCE TO RELATED APPLICATION

This application is a continuation of application Ser. No. 10/078,816, filed Feb. 19, 2002, now U.S. Pat. No. 7,365,238, the substance of which is incorporated herein by reference

FIELD OF THE INVENTION

This invention is directed to a dehydration indicator that may be used in conjunction with a wearable article. More particularly, the invention relates to hygienic absorbent articles, such as diapers, adult incontinence articles, feminine protection articles and the like including a dehydration indicator.

BACKGROUND OF THE INVENTION

Wearable and absorbent articles are well known in the art. Absorbent articles typically have an absorbent core, which is held or positioned against the body of the wearer during use by a fastening system, such that the bodily exudates are caught by the article. Typical absorbent articles include a topsheet facing the wearer which permits fluid exudates to pass through and a backsheet which prevents the exudates from escaping from the absorbent article. Many advancements have been made in the art since the introduction of the disposable absorbent article. However, most of these articles are not adapted to aid the caregiver in the monitoring of the health of the wearer. Certain attempts have been made in the art to include analysis of components of human waste, such as urine and feces, to provide indication of various specific health issues such as infections (e.g., urinary tract infections, etc.). For example, U.S. Pat. No. 5,468,236 issued to Everhart et al. on Nov. 21, 1995 discloses a disposable absorbent product that includes a chemically reactive means having an end point adapted to provide a visual indicator of the presence of a substance in mammalian bodily excrement. However, the prior art fails to provide the caregiver with a means of monitoring for the early indication of the onset of dehydration, often resulting in a delay in recognition of, and the ultimate diagnosis and treatment of, this issue for the wearer. Thus, it would be desirable to provide wearable articles with the capability to detect signals related to a dehydrated state of a wearer.

SUMMARY OF THE INVENTION

The present invention is directed to a wearable article comprising a dehydration indicator. The dehydration indicator is adapted to measure a urine ionic strength correlated to a specific gravity of the wearer's urine. The dehydration indicator provides a visible signal when the urine ionic strength reaches a value corresponding to a predetermined threshold value of the specific gravity. The threshold value is set at a level commonly accepted as being indicative of slight, moderate, or severe dehydration.

BRIEF DESCRIPTION OF THE DRAWINGS

FIG. 1 is a plan view of a disposable diaper embodiment of the present invention.

FIGS. 2A and 2B show a section view of a portion of alternative disposable diaper embodiments of FIG. 1.

FIG. 3 shows a generic qualitative dehydration indicator.

FIG. 4 shows a section view of a portion of the dehydration indicator of FIG. 3.

FIG. 5 shows a qualitative dehydration indicator having alphanumeric designations of the level of dehydration.

FIG. 6 shows an alternative dehydration indicator having numeric designations.

FIG. 7 shows a dehydration indicator having numerical values beside colored dots.

FIG. 8 shows a dehydration indicator having a color key beside a single colored dot.

FIG. 9 shows a disposable diaper embodiment having a fluid transport element.

DETAILED DESCRIPTION OF THE INVENTION

The present invention is directed to a dehydration indicator that may be used in conjunction with a wearable article, including but not limited to disposable absorbent articles. As used herein, the term “wearable article” refers to articles adapted to be applied or affixed to, or otherwise associated with a portion of a wearer's anatomy for a certain period of time, and often during a wearer's normal activities. Wearable articles may encircle or at least partially enclose a portion of a wearer's body, such as in the case of belts, diapers, training pants, underwear, other garments, and the like. Such wearable articles may include elastically extensible and/or fastening components to ensure a proper fit to the wearer and/or fastening components to provide for convenient application and removal of the article from the wearer by a caregiver. Alternatively, in addition to the above described features, at least a portion of the wearable article may be adhesively affixed to the skin of the wearer. In some embodiments, the wearable article may include a separate element, such as an insert, affixed to or associated with the wearable article. Although not limited to such embodiments, the present invention will generally be described below as associated with a disposable absorbent article.

As used herein, the term “absorbent article” refers to devices that absorb and contain body exudates and, more specifically, refers to devices that are placed against or in proximity to the body of the wearer to absorb and contain the various exudates discharged from the body. The term “disposable” is used herein to describe absorbent articles that generally are not intended to be laundered or otherwise restored or reused as absorbent articles, i.e., they are intended to be discarded after a single use and, preferably, to be recycled, composted or otherwise discarded in an environmentally compatible manner. A “unitary” absorbent article refers to absorbent articles that are formed of separate parts united together to form a coordinated entity so that they do not require separate manipulative parts like a separate holder and/or liner. A preferred absorbent article embodiment of the present invention is the unitary disposable absorbent article, diaper 20, shown in FIG. 1. As used herein, the term “diaper” refers to an absorbent article generally worn by infants and incontinent persons about the lower torso. The present invention is also applicable to other wearable and absorbent articles such as incontinence briefs, incontinence undergarments, absorbent inserts, diaper holders and liners, feminine hygiene garments, bandages and the like.

FIG. 1 is a plan view of the diaper 20 of the present invention in a flat-out state with portions of the structure being cut-away to more clearly show the construction of the diaper 20. The portion of the diaper 20 that faces the wearer is oriented towards the viewer. As shown in FIG. 1, the diaper 20 preferably comprises a liquid pervious topsheet 24; a liquid impervious backsheet 26; an absorbent core 28 that is preferably positioned between at least a portion of the topsheet 24 and the backsheet 26; side panels 30; elasticized leg cuffs 32; an elastic waist feature 34; and a fastening system generally designated 40. The diaper 20 is shown in FIG. 1 to have a first waist region 36, a second waist region 38 opposed to the first waist region 36 and a crotch region 37 located between the first waist region 36 and the second waist region 38. The periphery of the diaper 20 is defined by the outer edges of the diaper 20 in which longitudinal edges 50 run generally parallel to the longitudinal centerline 100 of the diaper 20 and end edges 52 run between the longitudinal edges 50 generally parallel to the lateral centerline 110 of the diaper 20.

While the topsheet 24, the backsheet 26, and the absorbent core 26 may be assembled in a variety of well known configurations, preferred diaper configurations are described generally in U.S. Pat. No. 3,860,003 entitled “Contractible Side Portions for Disposable Diaper” issued to Kenneth B. Buell on Jan. 14, 1975; U.S. Pat. No. 5,151,092 issued to Buell on Sep. 9, 1992; and U.S. Pat. No. 5,221,274 issued to Buell on Jun. 22, 1993; and U.S. Pat. No. 5,554,145 entitled “Absorbent Article With Multiple Zone Structural Elastic-Like Film Web Extensible Waist Feature” issued to Roe et al. on Sep. 10, 1996; U.S. Pat. No. 5,569,234 entitled “Disposable Pull-On Pant” issued to Buell et al. on Oct. 29, 1996; U.S. Pat. No. 5,580,411 entitled “Zero Scrap Method For Manufacturing Side Panels For Absorbent Articles” issued to Nease et al. on Dec. 3, 1996; and U.S. Pat. No. 6,004,306 entitled “Absorbent Article With Multi-Directional Extensible Side Panels” issued to Robles et al. 15 on Dec. 21, 1999; each of which is hereby incorporated herein by reference.

The backsheet 26 is generally that portion of the diaper 20 positioned adjacent garment facing surface 45 of the absorbent core 28 that prevents the exudates absorbed and contained therein from soiling articles that may contact the diaper 20, such as bedsheets and undergarments. The topsheet 24 is preferably positioned adjacent body facing surface 47 of the absorbent core 28 and may be joined thereto and/or to the backsheet 26 by any attachment means known in the art. As used herein, the term “joined” encompasses configurations whereby an element is directly secured to another element by affixing the element directly to the other element, and configurations whereby an element is indirectly secured to another element by affixing the element to intermediate member(s) which in turn are affixed to the other element. The topsheet 24 is preferably compliant, soft-feeling, and non-irritating to the wearer's skin. Further, at least a portion of the topsheet 24 is liquid pervious, permitting liquids to readily penetrate through its thickness.

The absorbent core 28 may comprise any absorbent material which is generally compressible, conformable, non-irritating to the wearer's skin, and capable of absorbing and retaining liquids such as urine and other certain body exudates. The absorbent core 28 may be manufactured in a wide variety of sizes and shapes and may comprise a wide variety of liquid-absorbent materials commonly used in disposable diapers and other absorbent articles such as comminuted wood pulp, which is generally referred to as airfelt. Examples of other suitable absorbent materials include creped cellulose wadding; meltblown polymers, including coform; chemically stiffened, modified or cross-linked cellulosic fibers; tissue, including tissue wraps and tissue laminates; absorbent foams; absorbent sponges; superabsorbent polymers; absorbent gelling materials; or any other known absorbent material or combinations of materials.

As noted above, the diaper 20 may also include a fastening system 40. The fastening system 40 preferably maintains the first waist region 36 and the second waist region 38 in a configuration so as to provide lateral tensions about the circumference of the diaper 20 to hold the diaper 20 on the wearer. The fastening system 40 preferably comprises a surface fastener such as tape tabs, hook and loop fastening components and/or hermaphroditic fastening components, although any other known fastening means are generally acceptable. In alternative embodiments, opposing sides of the article may be seamed or welded to form a pant. This allows the article to be used as a pull-on type diaper, such as a training pant.

The article of the present invention further comprises a dehydration indicator 60 that provides a qualitative or quantitative indication to a caregiver of the presence or degree of dehydration of the wearer of the article. It is typical in medical practice to use either urine osmolality or urine specific gravity to indicate the presence or degree of dehydration in human subjects. As is known in the art, osmolality is the concentration of an osmotic solution especially when measured in osmols or milliosmols per 1000 grams of solvent, with an osmol being a standard unit of osmotic pressure based on a one molal concentration of an ion in a solution. As the level of water in the subject's body, i.e., the level of hydration, decreases, the urine becomes more concentrated and its osmolality and specific gravity increase above commonly accepted thresholds. It is commonly accepted that urine osmolality is the most accurate measure of urine concentration as it is the measure most closely related to the physiology of urine concentration, in which the kidneys concentrate the urine based on the osmolal gradient. The specific gravity (SG) of the urine is also considered a valid estimate of urine concentration and can be converted into approximate osmolality by Equation 1.
mOsm/kg H20=(SG−1.000)×40,000  Equation 1

Comprehensive descriptions of the various methods of measuring and/or estimating urine concentration are presented in the following publications, the disclosures of which are hereby incorporated herein by reference: Chadha, et al, “Measurement of Urinary Concentration: a Critical Appraisal of Methodologies”, Pediatric Nephrology (2001), 16:374-382; and Burkhardt, et al, “A Reagent Strip for Measuring the Specific Gravity of Urine”, Clinical Chemistry, 28/10, 2068-2072 (1981).

The osmolality of urine is often measured in medical laboratories using either a freezing point osmometer (i.e., to measure freezing point depression) or a vapor pressure osmometer (i.e., to measure vapor pressure depression). Medical laboratories typically use a refractometer or hydrometer to measure the specific gravity of urine. However, these laboratory-based approaches to measuring urine osmolality or specific gravity are time consuming and require specialized equipment and/or training. Since the specific gravity of urine is correlated to the ionic strength of the urine, measurements of urine ionic strength are commonly used to estimate specific gravity in rapid screening assessments for the presence or severity of dehydration in a human subject. Accordingly, the dehydration indicator of the present invention is preferably responsive to elevated urine ionic strength and preferably provides an estimate of the urine specific gravity.

In certain embodiments, the dehydration indicator 60 may provide a qualitative visual indication that the ionic strength of the wearer's urine, and therefore the specific gravity of the urine, is above one or more predefined threshold values. The threshold values are preferably set at one or more levels commonly accepted as being indicative of slight, moderate, and/or severe dehydration. For example, in the United States, a 3-5% fluid deficit is commonly termed “mild” dehydration, commonly presenting symptoms of increased thirst, slightly dry mucous membranes, and dry warm skin. A 6-9% fluid deficit is typically regarded as “moderate” dehydration and may be accompanied by loss of skin turgor, dry mucous membranes, lack of tears, and poor blood profusion to the extremities. Fluid deficits of 10% or greater are termed “severe” dehydration and may present, in addition to the above symptoms, a sunken fontanel, lethargy, altered consciousness, and rapid deep breathing. Treatment of mild dehydration typically involves careful oral fluid replacement at home, while for moderate and severe dehydration medical attention should be sought, typically requiring intravenous fluid replacement.

Therefore, the dehydration indicator 60 may be designed, for example, to indicate to a mother or other caregiver when the specific gravity of the urine is in the range of about 1.020 to about 1.024, indicating mild dehydration, in the range of about 1.025 to about 1.029, indicating moderate dehydration, or above 1.030, indicating severe dehydration and the risk of anuria. In such cases, the dehydration indicator 60 functions as an “early warning” of dehydration and a signal to contact a physician and/or begin remedial treatment, such as administering electrolyte solutions orally, i.e., to initiate fluid replacement therapy. Table 1 provides data relating urine osmolality and average specific gravity for newborn infants from the Chadha, et al, reference above.

TABLE 1 Urine Osmolality (mOsmlkg) Urine Specific Gravity (via refractometer) 100 1.0055 200 1.011 300 1.016 400 1.0215 500 1.027 600 1.033

Table 2 provides data relating solution ionic strength to specific gravity measured via a refractometer, specific gravity measured using CHEMSTRIP™ urinalysis strips, and the qualitative color of the CHEMSTRIP™ urinalysis strips for various dilutions of a synthetic urine. Note: the urea content was not included in the calculation of synthetic urine ionic strength.

TABLE 2 Grams Grams Grams Grams Grams Grams dissolved in dissolved in dissolved dissolved dissolved dissolved 2000 ml 300 ml in 185 ml in 110 nil in 80 ml in 55 ml Synthetic Urine deionized deionized deionized deionized deionized deionized Component H2O H2O H2O H2O H2O H2O Urea 3.20 3.20 3.20 3.20 3.20 3.20 (NH4)H2P04 0.153 0.153 0.153 0.153 0.153 0.153 (NR4)2HP04 0.027 0.027 0.027 0.027 0.027 0.027 CaCl2•2H20 0.184 0.184 0.184 0.184 0.184 0.184 MgCl2•6H20 0.130 0.130 0.130 0.130 0.130 0.130 Na2SO4 0.122 0.122 0.122 0.122 0.122 0.122 KCl 1.76 1.76 1.76 1.76 1.76 1.76 Synthetic Urine Ionic 0.0169 0.113 0.183 0.307 0.422 0.615 Strength Specific Gravity via 1.002 1.008 1.014 1.020 1.025 1.035 refractometer Specific Gravity via 1.005 1.010 1.015 1.020 1.025 Off Scale CHEMSTRIP ™ at 1 >1.030 min. Color of Dark Green/Blue Olive Tan/Brown Light Orange CHEMSTRIP ™ SG Blue/Green Green Tan segment

In certain alternate embodiments, the dehydration indicator 60 may provide a more continuous indication of the status of the wearer's hydration level. For example, the dehydration indicator may change color, e.g., from blue to tan, or intensity as the ionic strength, and therefore the specific gravity, of the urine increases. The caregiver may then infer the degree of dehydration by comparing the color of the dehydration indicator to a diagnostic color chart. Alternatively, as shown in FIG. 2B, a translucent cover 90 having the same or similar shade as the dehydration indicator when it indicates a “normal” urine ionic strength/specific gravity may mask the dehydration indicator 60. In this embodiment, as the ionic strength/specific gravity of the urine increases and the dehydration indicator color changes, the dehydration indicator signal becomes visible due to its contrast/color difference versus the translucent mask 90. For example, in the embodiment described above, the dehydration indicator 60 may comprise a translucent masking cover 90 having a blue color as a top layer. As the urine ionic strength increases and the color shifts to tan, the signal will become visible through the cover 90 due to the contrast differences between the signal and the translucent cover 90.

Elevated urine ionic strength correlated to a urine specific gravity indicative of some level of dehydration may be signaled to the caregiver via visual, audible, and/or tactile signals. In preferred embodiments of the present invention, a visual signal is provided to the caregiver by the dehydration indicator 60. Examples of visual signals include having a color or pattern appear, disappear, or change in color, shape, or design, or any combination thereof. The pattern may, for example, include one or more stripes, dots, alphanumeric characters, symbols, or pictures, or any combination thereof. FIG. 3 depicts a qualitative dehydration indicator wherein the smaller box 65 changes color when contacted by urine having an ionic strength corresponding to a specific gravity above a threshold value. FIG. 6 depicts a qualitative dehydration indicator wherein the alphanumeric designations “1”, “2”, or “3” appear when contacted by urine having an ionic strength/specific gravity indicative of “mild, “moderate”, or “severe” dehydration, respectively, as currently understood in the medical field and as described above.

The dehydration indicator 60 may have the capability to indicate multiple urine ionic strength/specific gravity thresholds, providing a more quantitative indication of the presence or degree of dehydration. For example, the dehydration indicator 60 may indicate three urine ionic strength and/or specific gravity thresholds, indicating slight, moderate and severe dehydration. In a nonlimiting example, as shown in FIG. 5, the dehydration indicator 60 may provide separate signals for urine ionic strengths at levels associated with mild, moderate, and/or severe dehydration. Alternatively, the dehydration indicator 60 may include a multiplicity of urine ionic strength/specific gravity thresholds, each providing a separate signal, at regular intervals through the urine concentration region of interest. For example as shown in FIG. 7, the dehydration indicator 60 may have urine specific gravity thresholds (as estimated by urine ionic strength) at intervals of 0.005. In embodiments having more than one urine ionic strength/specific gravity threshold, the dehydration indicator 60 may provide different visual signals for each threshold (i.e., a different color, symbol, alphanumeric symbol, shape, etc., or combination thereof). In certain embodiments, two or more different urine ionic strength indicating chemistries having different dry and/or wet state colors may be employed to improve the interpretation of the signal from the dehydration indicator 60. For example, one urine ionic strength indicating chemistry may have a blue color when dry and a tan color when wet and a second urine ionic strength indicating chemistry may have a blue color when dry, but a red color when wet. In this example, the relative color change between the two indicators when wetted by urine having an ionic strength above a pre-defined threshold value is accentuated. In certain embodiments, each threshold may comprise a simple signal, e.g., a colored shape 85, next to an indicium 95 on the carrier element, examples of which are shown in FIGS. 5 and 7. Alternatively, as shown in FIG. 8, the indicia may comprise one or more colored zones 96 with which to compare the color of the dehydration indicating composition 70 following contact of urine with the dehydration indicator in order to assess the presence and/or severity of a dehydrated condition, i.e., the indicia may comprise a color key for the dehydration indicator signal.

Regardless of the number of urine ionic strength/specific gravity thresholds and/or the nature of the signal, the dehydration indicator 60 preferably provides a signal sufficiently durable, i.e., long lasting, so as to be readable at any time between the triggering urination event and the removal of the article by a caregiver. Typically, the signal should be visible for at least about 1 hour after contact with urine. Preferably, the signal should be visible for at least about 2 hours, and more preferably at least about 12 hours, after contact with urine.

Upon contact with urine having an ionic strength/specific gravity above the predefined threshold value, the dehydration indicator 60 should respond, i.e., provide a visible signal, prior to the time when the urine has dried or been contaminated to ensure the accuracy of the ionic strength measurement. If the response is delayed too long, the accuracy of the measurement of urine ionic strength may be adversely affected by either the artificial concentration of the urine by evaporation of its water component or the addition of ionic solutes in the form of contaminants. Typically, the dehydration indicator 60 provides a signal within about 5 minutes of contacting urine. Preferably, the dehydration indicator 60 provides a signal within about 1 minute, and more preferably within about 20 seconds, of contacting urine.

A qualitative dehydration indicator 60 may indicate an elevated urine ionic strength (i.e., specific gravity) by having a color or pattern appear, disappear, or change in color, shape, or design, or any combination thereof. The pattern may, for example, include one or more stripes, dots, alphanumeric characters, symbols, or pictures, or any combination thereof. The dehydration indicator 60 may be visible from inside the article or outside the article and may be affixed to or disposed with any component of the article. For example, the dehydration indicator 60 may be affixed to the topsheet 24, the absorbent material 28, inner leg cuffs, also known as barrier cuffs (not shown in the drawings), or the backsheet 26. In certain preferred embodiments, a non-limiting example of which is depicted in FIG. 2A, the dehydration indicator 60 is positioned directly beneath the topsheet 24 and is visible after the article is at least partially removed from the wearer. In certain alternative embodiments, the dehydration indicator 60 may be positioned on the inside of the article such that it can be seen through at least a portion of the outer cover. In yet other embodiments, the dehydration indicator 60 may be disposed on the article in such a way that a patch or portion of the article can be pulled away, permanently or temporarily, such that the indicator is visible without the article being removed from the wearer. In yet other embodiments, the dehydration indicator 60 may comprise a separate element applied to the article by the caregiver, such as a diaper insert or other carrier element affixed to the topsheet 24, i.e., via adhesive, a mechanical fastener, friction, etc., by the caregiver prior to applying the article to the wearer.

For a given dehydration indicating composition 70, the specific color change associated with urine having various ionic strengths and specific gravities, e.g., various threshold values, must be determined via application of urine or synthetic urine having known specific gravities (preferably at the threshold values) and careful observation and recording of the resultant color of the dehydration indicating composition 70. Preferably, the interpretation of the signal by the caregiver is facilitated via a translucent mask 90, indicia on the dehydration indicator 60 functioning as a color key 110 as shown in FIG. 8, a separate color key provided by the manufacturer, or any other visual means based on the defined color changes associated with the ionic strength/specific gravity threshold value(s) for the given dehydration indicating composition 70.

The dehydration indicator 60, or any of the components thereof such as a dehydration indicating composition 70, may be applied to a substrate, such as the article or any component thereof, or to a carrier element, via any means known in the art. For dehydration indicators, or components thereof, that are applied in a liquid state to the substrate in a continuous or intermittent mode, or in patterns, suitable exemplary processes include slot coating, gravure printing, inkjet printing, spraying, screening, and the like. The indicator may also be applied to the substrate or article in a solid form, such as films, webs, fibers, or particles via continuous unwind processes, cut & slip processes, air deposition, and the like, and may be joined to the substrate via physical entanglement, entrapment, adhesives or any other means as known in the art. If the dehydration indicating composition 70 is applied to the substrate in an aqueous form, the dehydration indicating composition may be subsequently dried to remove any excess water.

As noted above and shown in FIGS. 3 and 4, the dehydration indicator 60 may comprise a dehydration indicating composition 70 disposed on or in a substrate, or carrier element 80. The carrier element 80 may comprise a web-like component such as a film, woven or nonwoven material, foam, scrim, or celluosic material, to which the dehydration indicating composition or element is applied or affixed. Alternately, the carrier 80 may enclose or encapsulate a dehydration indicating composition to prevent its migration or loss within the article before or during use. In these embodiments, the carrier 80 may comprise one layer folded back upon itself or may comprise a multiplicity of layers. If more than one layer is employed, the various layers may have different properties or comprise different materials. For example, a dehydration indicating composition 70 may be disposed between a permeable top (i.e., wearer-facing) layer and an impermeable bottom layer. In certain embodiments, the top layer may alternatively comprise a selectively permeable layer 75, a dissolving layer, a pH sensitive layer, or a coating. Exemplary selectively permeable layers may include meshes, tissues, micro or macroporous films, semipermeable membranes, and other selectively permeable materials as known in the art. Suitable exemplary semipermeable membranes include cellulose acetate, cellulose diacetate, cellulose triacetate, agar acetate, beta glucan acetate, polymeric epoxides, semipermeable polyurethanes, and semipermeable polyglycolic acid. In certain alternate embodiments, the dehydration indicator 60 may be detachable from the article.

While the dehydration indicator 60 may be located at any point in the article likely to be contacted by urine, the dehydration indicator 60 is preferably located in the portion of the article coordinated with the urine loading point, i.e., the location in which the urine typically insults the article. For instance, the dehydration indicator 60 may be located on or affixed to the topsheet, backsheet, and/or inner leg cuffs. Preferably, the urine ionic strength is measured at or near the topsheet of the article, e.g., on the wearer facing side or underside of the topsheet, in order to minimize the likelihood of contamination of the urine by other components of the article, such as the absorbent core. In many occurrences where the dehydration indicator is located at or near the inner surface of the backsheet, or on any carrier disposed on the underside of an absorbent core, the dehydration indicator may be limited to detecting an elevated urine ionic strength for only the initial urine loading event since relatively large quantities of existing fluid held in the absorbent core may leach electrolytes from absorbent materials such as cellulosic fibers, absorbent foams, and/or superabsorbent polymers which could result in an erroneous urine ionic strength measurement.

In certain alternate embodiments of the present invention, a nonlimiting example of which is depicted in FIG. 9, the dehydration indicator 60 may be located in regions of the article other than the urine loading zone. In these embodiments, urine is transported to the urine indicator 60 from the urine loading zone by a fluid transport element 100 in fluid communication with the dehydration indicator 60. In these embodiments, at least a portion of the fluid transport element 100 is located in, or adjacent to, the urine loading zone in order to acquire fluid prior to transporting, e.g., wicking, fluid to the dehydration indicator 60. The fluid transport element 100 may comprise any material or structure as known in the art which is capable of transporting fluid from the urine loading zone to the dehydration indicator. Suitable materials for the fluid transport element 100 include cellulosic materials, e.g., fluff, airfelt, wetlaid fibers webs, tissues, foams, nonwovens, sponges, capillary channel fibers, and the like. Alternatively, the fluid transport element may comprise two or more layers of fluid impermeable material having one or more capillary openings between at least two of the layers, the capillary openings providing fluid communication between the urine source and the dehydration indicator.

EXEMPLARY EMBODIMENTS Example 1

A wearable article having a qualitative dehydration indicator may be constructed as follows:

    • a) An aqueous urine ionic strength indicating solution is prepared according to the formula:
      • 1.0 liter of deionized water
      • 0.120 moles Nitrilo-tris-(methylenephosphonic acid)
      • 1.5 grams bromothymol blue indicator
    • b) The pH of the solution from a) above is titrated to a final pH in the range of about pH 7.9 to about 8.1 using a 3.5 N aqueous tetramethylammonium hydroxide solution. The pH is measured using a standard electronic pH meter calibrated according to the manufacturer's instructions. The 3.5 N aqueous tetramethylammonium hydroxide solution is added in volume increments as described below and the pH meter reading is allowed to stabilize after each incremental volume prior to the addition of the next incremental amount. The solution is continuously mixed during the entire titration process. The 3.5 N aqueous tetramethylammonium hydroxide solution is initially added to the solution from a) in increments of 25 ml until the pH of the resultant solution is in the range of about pH 6.0 to about 6.5. Once the pH reaches this range, the 3.5 N aqueous tetramethylammonium hydroxide solution is added in increments of 10 ml until the pH of the resultant solution is in the range of about pH 7.0 to about 7.5. Subsequently, the 3.5 N aqueous tetramethylammonium hydroxide solution is added in incremental volumes of 0.1 to 1.0 ml until the desired pH range of about 7.9 to about 8.1 is attained.
    • c) A piece of white paper towel, such as BOUNTY™ paper towel, available from The Procter & Gamble Co. of Cincinnati, Ohio, U.S.A. is impregnated with the resultant pH-adjusted solution and dried.
    • d) A strip of the treated paper towel is cut in a rectangular form having dimensions of 0.5 cm×2 cm and is adhesively affixed along its perimeter to the garment-facing side of a disposable diaper topsheet in the crotch or urine loading region of the product.

Example 2

A wearable article having a qualitative dehydration indicator may be constructed as follows:

    • a) An aqueous urine ionic strength indicating solution is prepared according to the formula:
      • 1.0 liter of deionized water
      • 0.060 moles sodium dihydrogen phosphate
      • 0.040 moles 2-(N-morpholino)-ethanesulfonic acid (MES)
      • 7.5 grams bis-(aminoethyl-)glycol ether N,N,N′,N′-tetraacetic acid
      • 1.5 grams bromothymol blue indicator
    • b) The pH of the solution from a) above is titrated to a final pH in the range of about pH 7.9 to about 8.1 using a 10 N aqueous sodium hydroxide solution. The pH is measured using a standard electronic pH meter calibrated according to the manufacturer's instructions. The 10 N aqueous sodium hydroxide solution is added in volume increments as described below and the pH meter reading is allowed to stabilize after each incremental volume prior to the addition of the next incremental amount. The solution is continuously mixed during the entire titration process. The 10 N aqueous sodium hydroxide solution is initially added to the solution from a) in increments of 5 ml until the pH of the resultant solution is in the range of about pH 6.0 to about 6.5. Once the pH reaches this range, the 10 N aqueous sodium hydroxide solution is added in increments of 1.0 ml until the pH of the resultant solution is in the range of about pH 7.0 to about 7.5. Subsequently, the 10 N aqueous sodium hydroxide solution is added in incremental volumes of 0.1 ml until the desired pH range of about 7.9 to about 8.1 is attained.
    • c) A piece of white paper towel, such as BOUNTY™ paper towel, available from The Procter & Gamble Co. 25 of Cincinnati, Ohio, U.S.A. is impregnated with the resultant pH-adjusted solution and dried.
    • d) A strip of the treated paper towel is cut in a rectangular form having dimensions of 0.5 cm×2 cm and is adhesively affixed along its perimeter to the garment-facing side of a disposable diaper topsheet in the crotch or urine loading region of the product.

Example 3

A wearable article having a qualitative dehydration indicator may be constructed as follows:

    • a) A solution is prepared consisting of 20 grams of maleic anhydride/methylvinylether copolymer in its free acid form in 1.0 liter of deionized water. The free acid form of the maleic anhydride/methylvinylether copolymer is water soluble and has a mass average molecular weight of about 1,500,000. This copolymer is currently commercially available as GANTREZ™ S-97 from International Specialty Products of Wayne, N.J., U.S.A. This copolymer is commonly designated CAS #25 153 40-06. The CAS# refers to the unique numerical designation assigned to a chemical by the Chemical Abstracts Service (CAS) of Columbus, Ohio, USA, which is a division of the American Chemical Society of Washington, D.C., USA.
    • b) This solution is titrated with a 10 N sodium hydroxide solution until the resultant solution pH is in the range of about pH 7.9 to about 8.1 following the procedure in step 2) of Example 2 above.
    • c) A strip of filter paper, e.g., No. 204 from Eaton-Dikeman Scientific Specialties, Co. of Mt. Holly Springs, Pa., U.S.A., is immersed in the partially neutralized solution from the previous step, removed, and subsequently dried.
    • d) The dried polymer-bearing strip is then immersed in a solution comprising 1.2 grams of bromothymol blue per liter of methanol, removed, and subsequently dried.
    • e) A piece of the resultant treated filter paper is cut into a rectangular form having dimensions of 0.5 cm×2 cm and is adhesively affixed to a 1.0 mil polypropylene film, such as is currently available as X15306 from Tredegar Industries of Terre Haute, Ind., U.S.A.
    • f) The filter-paper side of the resultant composite is affixed along its perimeter to the garment-facing side of a disposable diaper topsheet in the crotch or urine loading region of the product.

Example 4

A wearable article having a qualitative dehydration indicator may be constructed as follows:

    • a) A urinalysis test strip adapted to provide an indication of urine specific gravity via measurement of the ionic strength of the urine is provided. A suitable currently available urinalysis test strip is the CHEMSTRIP™ 10 urinalysis strip available from Roche Diagnostics of Indianapolis, Ind., U.S.A. The “specific gravity” measuring section of the urinalysis test strip containing a urine ionic strength indicating composition, such as ethyleneglycol-bis[aminoethyl ether] tetraacetic acid and bromothymol blue, is cut from the test strip.
    • b) The cut segment from a) is adhesively affixed to the garment-facing side of a disposable diaper topsheet in the crotch or urine loading region of the product, oriented such that the reagent-containing side is facing the topsheet. Care is taken to avoid covering the entire surface of the reagent strips segment with adhesive to allow urine to contact the strip and provide a signal. In the case of the CHEMSTRIP™ 10 urinalysis strip, when the color changes to tan, the urine specific gravity is approximately 1.030, indicating a condition of severe dehydration. In the case of other test strips, the manufacturer's instructions for reading the color signal for a given test strip should be followed.

Claims

1. A disposable absorbent article or receiving and containing bodily exudates including urine from a wearer, the disposable absorbent article comprising;

an outer cover adapted to fit about a portion of the wearer;
a fluid permeable topsheet onto and through which the urine is received;
an absorbent structure disposed adjacent at least a portion of the outer cover; and
a dehydration indicator adapted to measure a urine ionic strength correlated to a specific gravity of the wearer's urine and provide a visible signal when the urine ionic strength reaches a value corresponding to a predetermined threshold of the specific gravity, the dehydration indicator comprising a chemical indicating composition providing a visible signal indicative of a level of dehydration in response to an ionic strength of urine exuded into the disposable absorbent article by a wearer, wherein the chemical indicating composition is covered on a wearer-facing surface by a semipermeable membrane formed of cellulose acetate, cellulose diacetate, cellulose triacetate, agar acetate, beta glucan acetate, polymeric epoxides, semipermeable polyurethanes, or semipermeable polyglycolic acid.

2. The absorbent article of claim 1 wherein the dehydration indicator provides a qualitative indication of a urine specific gravity associated with dehydration.

3. The absorbent article of claim 1 wherein the dehydration indicator comprises an indicium.

4. The absorbent article of claim 3 wherein the indicium serves as a color key for the dehydration indicator signal.

5. The disposable absorbent article of claim 1 wherein the dehydration indicator is disposed on at least a portion of the topsheet.

6. The disposable absorbent article of claim 5 wherein the dehydration indicator is detachable from the topsheet.

7. The disposable absorbent of claim 1 further comprising a translucent cover covering the dehydration indicator.

8. The disposable absorbent article of claim 1 wherein the dehydration indicator is disposed on a carrier element.

9. The disposable absorbent article of claim 1 additionally comprising a fluid transport element in fluid communication with the dehydration indicator and serving to transport urine to the dehydration indicator.

Referenced Cited
U.S. Patent Documents
3848594 November 1974 Buell
3860003 January 1975 Buell
3911173 October 1975 Sprague, Jr.
3929135 December 1975 Thompson
4121011 October 17, 1978 Glover et al.
4231370 November 4, 1980 Mroz et al.
4318709 March 9, 1982 Falb et al.
4324246 April 13, 1982 Mullane et al.
4334920 June 15, 1982 Mori et al.
4342314 August 3, 1982 Radel et al.
4351183 September 28, 1982 Ehbert
4381781 May 3, 1983 Sciaraffa et al.
4463045 July 31, 1984 Ahr et al.
4515595 May 7, 1985 Kievit et al.
4573986 March 4, 1986 Minetola et al.
4609518 September 2, 1986 Curro et al.
4610678 September 9, 1986 Weisman et al.
4629643 December 16, 1986 Curro et al.
4636207 January 13, 1987 Buell
4662875 May 5, 1987 Hirotsu et al.
4673402 June 16, 1987 Weisman et al.
4695278 September 22, 1987 Lawson
4699622 October 13, 1987 Toussant et al.
4704115 November 3, 1987 Buell
4705513 November 10, 1987 Sheldon et al.
4710189 December 1, 1987 Lash
4785996 November 22, 1988 Ziecker et al.
4795454 January 3, 1989 Dragoo
4808178 February 28, 1989 Aziz et al.
4816025 March 28, 1989 Foreman
4826550 May 2, 1989 Shimizu et al.
4834735 May 30, 1989 Alemany et al.
4842666 June 27, 1989 Werenicz
4846815 July 11, 1989 Scripps
4857067 August 15, 1989 Wood et al.
4888231 December 19, 1989 Angstadt
4892536 January 9, 1990 Desmarais et al.
4894060 January 16, 1990 Nestegard
4900317 February 13, 1990 Buell
4909803 March 20, 1990 Aziz et al.
4931051 June 5, 1990 Castello
4938753 July 3, 1990 Van Gompel et al.
4940464 July 10, 1990 Van Gompel et al.
4946527 August 7, 1990 Battrell
4963140 October 16, 1990 Robertson et al.
4968312 November 6, 1990 Khan
4988344 January 29, 1991 Reising et al.
4988345 January 29, 1991 Reising
4990147 February 5, 1991 Freeland
5006394 April 9, 1991 Baird
5026364 June 25, 1991 Robertson
5037416 August 6, 1991 Allen et al.
5062840 November 5, 1991 Holt et al.
5085654 February 4, 1992 Buell
5092816 March 3, 1992 Levasseur
5137537 August 11, 1992 Herron et al.
5140393 August 18, 1992 Hijikihigawa et al.
5147345 September 15, 1992 Young et al.
5151092 September 29, 1992 Buell et al.
5171236 December 15, 1992 Dreier et al.
5181905 January 26, 1993 Flam
5197958 March 30, 1993 Howell
5221228 June 22, 1993 Pedroia
5221274 June 22, 1993 Buell et al.
5242436 September 7, 1993 Weil et al.
5246433 September 21, 1993 Hasse et al.
5260345 November 9, 1993 Desmarais et al.
5269755 December 14, 1993 Bodicky
5269775 December 14, 1993 Freeland et al.
5306266 April 26, 1994 Freeland
5342338 August 30, 1994 Roe
5387207 February 7, 1995 Dyer et al.
5389093 February 14, 1995 Howell
5397318 March 14, 1995 Dreier
5458140 October 17, 1995 Eppstein et al.
5468236 November 21, 1995 Everhart et al.
5492751 February 20, 1996 Butt, Sr. et al.
5499978 March 19, 1996 Buell et al.
5507736 April 16, 1996 Clear et al.
5507760 April 16, 1996 Wynne et al.
5514121 May 7, 1996 Roe et al.
5518801 May 21, 1996 Chappell et al.
5540671 July 30, 1996 Dreier
5554142 September 10, 1996 Dreier et al.
5554143 September 10, 1996 Roe et al.
5554145 September 10, 1996 Roe et al.
5569234 October 29, 1996 Buell et al.
5571096 November 5, 1996 Dobrin et al.
5580411 December 3, 1996 Nease et al.
H1630 January 7, 1997 Roe et al.
5591152 January 7, 1997 Buell et al.
5609587 March 11, 1997 Roe
5625222 April 29, 1997 Yoneda et al.
5635191 June 3, 1997 Roe et al.
H1670 July 1, 1997 Aziz et al.
5643588 July 1, 1997 Roe et al.
5653703 August 5, 1997 Roe et al.
5669897 September 23, 1997 Lavon et al.
5865823 February 2, 1999 Curro
5897545 April 27, 1999 Kline et al.
5922283 July 13, 1999 Hsu
5938648 August 17, 1999 Lavon et al.
5941864 August 24, 1999 Roe
5947943 September 7, 1999 Lee
5957908 September 28, 1999 Kline et al.
5968025 October 19, 1999 Roe et al.
5977430 November 2, 1999 Roe et al.
5997520 December 7, 1999 Ahr et al.
6004306 December 21, 1999 Robles et al.
6013063 January 11, 2000 Roe et al.
6106461 August 22, 2000 Roskin et al.
6118041 September 12, 2000 Roe et al.
6120487 September 19, 2000 Ashton
6120489 September 19, 2000 Johnson et al.
6149636 November 21, 2000 Roe et al.
6168584 January 2, 2001 Allen et al.
6186991 February 13, 2001 Roe et al.
6203496 March 20, 2001 Gael et al.
6399853 June 4, 2002 Roe et al.
6432098 August 13, 2002 Kline et al.
6476288 November 5, 2002 Vanrijswijck et al.
6479727 November 12, 2002 Roe
6515194 February 4, 2003 Neading et al.
6617488 September 9, 2003 Springer et al.
6627394 September 30, 2003 Kritzman et al.
6627787 September 30, 2003 Roe et al.
6680422 January 20, 2004 Roe
6716441 April 6, 2004 Osborne et al.
7002054 February 21, 2006 Allen et al.
7105715 September 12, 2006 Carlucci et al.
7365238 April 29, 2008 Diehl et al.
20030233082 December 18, 2003 Kline et al.
20040087922 May 6, 2004 Bobadilla
20050177120 August 11, 2005 Olson et al.
20060025732 February 2, 2006 Ying et al.
20070270773 November 22, 2007 Mackey
20080021423 January 24, 2008 Klofta et al.
20080021428 January 24, 2008 Klofta et al.
20080021429 January 24, 2008 Klofta et al.
Foreign Patent Documents
198 37 678 March 2000 DE
203 13 784 December 2003 DE
0 114 315 June 1987 EP
0 560 099 September 1993 EP
0 611 966 August 1994 EP
60-161108 August 1985 JP
01-266202 October 1989 JP
05-180846 July 1993 JP
06-063027 September 1994 JP
10-313894 December 1998 JP
2001-327530 November 2001 JP
2009-018183 January 2009 JP
WO-94/14395 July 1994 WO
WO-94/24557 October 1994 WO
WO-95/16746 June 1995 WO
WO-95/24173 September 1995 WO
WO-97/34014 September 1997 WO
WO-98/27417 June 1998 WO
WO-99/31486 June 1999 WO
WO-01/54552 January 2001 WO
WO-01/50996 July 2001 WO
WO-01/54552 August 2001 WO
WO-03/002050 January 2003 WO
WO-2007/077538 July 2007 WO
Other references
  • Chadha, et al., “Measurement of Urinary Concentration: A Critical Appraisal of Methodologies”, Pediatric Nephrology, vol. 16, 2001, pp. 374-382, XP-002244663.
  • A Reagent Strip for Measuring the Specific Gravity of Urine, Clinical Chemistry, 28/10, 2068-2072 (1982).
Patent History
Patent number: 8217217
Type: Grant
Filed: Mar 7, 2008
Date of Patent: Jul 10, 2012
Patent Publication Number: 20080215024
Assignee: The Procter & Gamble Company (Cincinnati, OH)
Inventors: Joseph Raymond Diehl (Hamilton, OH), Donald Carroll Roe (West Chester, OH), Patrick Jay Allen (Cincinnati, OH)
Primary Examiner: Lynne Anderson
Attorney: Thibault Fayette
Application Number: 12/043,979
Classifications