Abstract: A housing for accommodating optical and electronic components of a video camera of a medical video endoscope. The housing including: a first housing part, a second housing part, the housing parts assembled together to form inner chambers for mounting the optical and electronic components and an axial passage for optically connecting the inner chambers; a window disposed in an end opening in the assembled housing parts, electrical connectors disposed in a wall in the assembled housing parts, wherein, in an unassembled configuration, the inner chambers are accessible from a surface substantially transversely to a longitudinal axis of the housing parts, and the first and second housing parts are configured to mate with each other in such a way that the inner chambers are hermetically sealed from an exterior of the assembled first and second housing parts.

Abstract: An endoscopic device that irradiates a plurality of illuminating lights having different spectrums from each other onto a subject at a front edge of an endoscope inserting module and captures the subject to obtain an observation image, includes an illuminating module that generates the plurality of illuminating lights, an imaging module that captures the subject and outputs an image signal of the observation image, a light intensity ratio control module that controls the illuminating module to irradiate the plurality of illuminating lights onto the subject with a set light intensity ratio by setting the light intensity ratio of the plurality of illuminating lights for every observation image, and a color tone correcting module that corrects the color tone of the image signal so as to obtain the observation image with substantially a same color tone even though the light intensity ratio is changed.

Abstract: A camera system, particularly for minimally-invasive surgery, comprising an optics, wherein the optics is connected to at least one transparent film and the film is removable. Further, there is provided a method for cleaning a camera in minimally-invasive surgery wherein an optics of the camera is cleaned intra-corporally by use of a cleaning device.

Abstract: A laparoscope comprises an elongated insertion tube having an open distal end. Optical means are provided for conducting an optical image of a target. The optical means includes an objective lens. A transparent sphere houses the lens. The sphere is rotatably disposed in the distal end of the tube such that a portion of the sphere protrudes from the tube. A ring-shaped wiper is fixed to the distal end of the tube for circumferentially engaging the sphere. Means are disposed in the tube for rotating the sphere, wherein the wiper removes debris and fluids from the surface of the sphere as the sphere rotates.

Abstract: A system including catheter endoscope for deployment in the bladder of a patient to provide a visual display of the bladder's mucosal surface is disclosed. The catheter endoscope is an elongated member having an image acquisition component and an expandable positioning component. The catheter is deployed such that the expandable positioning component is in the bladder adjacent the bladder's neck with the image acquisition component held away from any portion of the mucosal surface. The image acquisition component is arranged to acquire a panoramic image of a sector of the mucosal surface of the bladder from the neck of the bladder to the mucosal surface of the bladder opposite the neck of the bladder and to be rotated about the axis along which the catheter is inserted to acquire an image of the entire mucosal surface of the bladder which is displayed on a monitor forming a portion of the system.

Abstract: Systems and methods for measuring dysphotopsia are provided. These systems and methods can be used to objectively quantify positive and negative dysphotopsia. One embodiment provides a system and method for determining dysphotopsia that uses a first light source configured to provide light energy to illuminate a model eye, a refractor for refracting the light energy from the first light source and directing it into the model eye, a first electronic light sensor for measuring an amount of light in the model eye; a second light source configured to provide light energy to illuminate the model eye, wherein the light energy from the second light source is introduced at an angle from the first light source; and a second electronic light sensor for measuring the amount of light in the model eye, wherein the second electronic light sensor is capable of taking measurements from various points around the model eye. Data from these measurements can then analyzed to provide an objective measurement of dysphotopsia.

Abstract: In one aspect, there is provided a handheld vision tester. In this particular embodiment, the handheld vision tester comprises a display, cursor control, and an interface port. The display delivers vision tests to a user. The user interacts with the vision tests by using the display and cursor control. The interface port allows for communication of results of the vision tests from the handheld tester to external devices.

Abstract: An apparatus for measuring eye's moisture 1 includes: a detection surface 30 placed on a position in contact with a conjunctiva, a sclera, or a cornea or a position opposed to a conjunctiva, a sclera, or a cornea; and a capacitance sensor 40 provided on the detection surface 30. As a result, an apparatus and a method for measuring eye's moisture that are capable of simply and objectively measuring the state of tear fluid are provided.

Abstract: Systems and methods for determining thickness of lipid and aqueous layers of a tear film in which a spectrum array is generated from optical coherence tomography and input into a statistical estimator, which determines the thickness of the lipid and/or aqueous layers at a nanometer resolution based on the inputted spectrum and other information, such as information about a laser intensity noise, Poisson noise, and dark noise associated with the OCT.

Abstract: A scanning laser ophthalmoscope (SLO) for imaging the retina of an eye comprises a source (12) of collimated light, a scanning device (14, 16, 1328, 1319), a scan transfer device (20) and a detector (1310). The scan transfer device has a first focus (16) at which an apparent point source is provided and a second focus (24) at which an eye (524, 1324) may be accommodated. The scan transfer device transfers a two-dimensional collimated light scan from the apparent point source into the eye. An optical coherence tomography (OCT) system (900) is combined with the SLO, the OCT system providing OCT reference and sample beams. The OCT sample beam (902) propagates along the same optical path as of the SLO collimated light through the scan transfer device. An aberration compensator (1204, 1316) automatically compensates for systematic aberrations and/or changes in wavefront introduced by scanning elements and the scan transfer device as a function of scan angle.

Abstract: An autorefractor-keratometer device including a first laser scanning device that emits a plurality of laser scans, a second laser device that emits a laser pulse, a first detector that detects the plurality of emitted laser line scans to determine corneal topography, and a second detector that detects a reflection of the emitted laser pulse to determine sphero-cylinder refraction.

Abstract: The present invention discloses systems and methods for determine preoperative estimation of postoperative IOL position (or the EAPD) in accordance with one or both of the following mathematical relationships, which are derived from linear regression: EAPD=S1+(S2×AND)+(S3×NT)+(S4×AL), ??(1a) EAPD=W1+(W2×AND)+(W3×RND)+(W4×AL), ??(1b) where S1, S2, S3, and S4 for equation (1a) and W1, W2, W3, and W4 for equation (1b) are statistically derived linear regression constant coefficients.

Abstract: A method for interactive adjustment of a parameter of a continuously variable optical lens involving having a subject view an eye chart through a variable lens frame comprising at least one continuously variable optical lens, applying a modulation to a selected parameter of said continuously variable optical lens around an average value, and tuning said average value by minimizing the flickering visible to the subject and due to the modulation.

Abstract: A parallel detecting optical coherence tomography (OCT) setup and method, in which the light paths of the illumination of the sample and of the detection of the backscattered light do not use the same apertures. The separation of illumination and detection apertures filters these disturbing reflexes from the backscattered light of the sample and significantly increases image quality.

Abstract: There are disclosed systems, devices, and methods for generating insights relating to patient health using a social networking platform interconnecting a patient with a plurality of care givers. The patient is provided access to a computer application configured to solicit and collect patient data from the patient, the computer application selected based on at least one characteristic of the patient. First patient data reflective of the health condition of the patient, as collected by the computer application, are received through the social networking platform. A communication from a care giver is transmitted to the patient through the social networking platform. Second patient data reflective of the health condition responsive to the transmitted communication are received through the social networking platform. The first and second patient data are analyzed to determine at least one insight relating to health of the patient; and a report is generated to present the insight.

Abstract: Assessing acquisition of information related to a stimulus can be accomplished by providing a stimulus, recording a free recall response in natural language of the stimulus by a subject, and determining automatically a similarity. The similarity is between the recorded free recall response and a database comprising one or more control responses associated with the stimulus. A higher similarity indicates greater information acquisition by the subject. Related apparatus, systems, techniques, and articles are also described.

Abstract: According to an exemplary embodiment of the present disclosure, an apparatus can be provided which can include at least one first arrangement providing a radiation, and including a splitter structure separating the radiation into at least one first electro-magnetic radiation directed to a sample and at least one second electro-magnetic radiation directed to a reference. A frequency of the radiation provided by the first arrangement can be varied over time by the first arrangement. The apparatus can also include at least one detector second arrangement configured to detect a first interference and a second interference between at least one third radiation associated with the first radiation(s) and at least one fourth radiation associated with the second radiation(s), whereas the first and second interferences can be different from one another.

Abstract: A method and system for medical imaging employs an excitation source configured to cause an object having a plurality of cells to at least one of emit, reflect, and fluoresce light. An optical receptor is employed that is configured to receive the light from the object. A filter assembly receives the light from the optical receptor and filters the light. An image processor having a field of view (FOV) substantially greater than a diameter of a cell of the object and an analysis resolution substantially matched to the diameter of a cell of the object that receives the filtered light from the filter and analyzes the filtered light corresponding to each cell in the FOV. A feedback system is provided that is configured to provide an indication of a state of each cell in the FOV and a location of a cell in the FOV meeting a predetermined condition.

Abstract: A probe head for a diagnostic instrument, the probe head comprising; a transmission optical fiber, a plurality of collection optical fibers, and a lens to transmit light from the transmission optical fiber to a test site, wherein the ends of the collection optical fibers are bevelled.

Abstract: A system and method for acquiring and sharing in real time video and/or still images with a tooth or tooth root during a dental procedure using an endoscope.

Abstract: Disclosed is a method of generating a diagnostic image by using a photoacoustic material. The method includes determining a wavelength band of light maximally absorbed by a photoacoustic material, based on at least one or more photoacoustic materials injected into an object, irradiating light, which corresponds to the determined wavelength band, onto an internal region of interest (ROI) of the object to acquire a photoacoustic signal corresponding to the irradiated light, generating a photoacoustic image indicating the ROI by using the photoacoustic signal, and combining and displaying the generated photoacoustic image and an image expressing that the light is being irradiated onto the ROI.

Abstract: Provided herein are system and methods for monitoring and guiding thermal therapy procedures within a human or animal tissue. The system comprises a therapeutic module configured to apply thermal treatment to a subject; an ultrasound imaging module; an optoacoustic imaging module; a processing module connected to both ultrasound and optoacoustic based imaging module; and an operating controlling module connected with said processing module and configured to manipulate at least one of said therapeutic module, ultrasound imaging module or optoacoustic imaging module. The calibration method is able to eliminate the inconsistency of optoacoustic based temperature measurements caused by sample-to-sample and spatial variations of Gruneisen parameter for different tissues. The method for temperature-structure imaging is able to generate both two dimensional and three dimensional co-registered structure and temperature images for the tissues inside a region of interest of a subject.

Abstract: A thermometry apparatus includes a distal probe tip having a hollow interior. An insulating support is at least partially disposed within the interior of the distal probe tip. The insulating support is configured to receive at least one of at least one heating element and at least one temperature sensing element. According to one version, the insulating support is a flexible circuit strip configured to receive the at least one heating element(s) to protect the leads from damage and premature breakage.

Abstract: Disclosed herein is a method where a thermography device collects raw data that is forwarded to a server wherein the server runs the raw data through a database of signature parameters and generates a report. After the report is generated, the server notifies a technician that a report has been created and makes the report available online for the technician to login and retrieve. The separation of the measurement system and the analysis system allows some protection of trade secrets which are contained within the analysis software.

Abstract: Disclosed herein is a method of diagnosis for various conditions through use of a thermograph. Body temperatures measured at selected sites on the body observed before and after stimulus present data which when analyzed provides for reliable suspicions for selected conditions. Analysis of data includes several constructed indices and mathematical expressions used diagnose conditions of vulnerabilities to conditions.

Abstract: A sensor for physiology sensing may be configured to generate oscillation signals for emitting radio frequency pulses for range gated sensing. The sensor 402 may include a radio frequency transmitter configured to emit the pulses and a receiver configured to receive reflected ones of the emitted radio frequency pulses. The received pulses may be processed to detect physiology characteristics such as motion, sleep, respiration and/or heartbeat. In some embodiments, the sensor may employ a circuit including a pulse generator configured to generate signal pulses. The circuit may also include a dielectric resonator oscillator configured to generate a radio frequency oscillating signal. A switched oscillation circuit may be coupled to the pulse generator and the dielectric resonator oscillator. The switched circuit may be configured to generate a pulsed radio frequency oscillating signal for emitting the radio frequency pulses.

Abstract: The present invention relates to a system, method and apparatus for measuring vascular parameters and, more particularly, but not exclusively, to a system, method and apparatus for monitoring changes in the equivalent inner diameter of small branching arteries and arterioles. An aspect of some embodiments of the invention concerns finding a measure of a blood flow dependent parameters in small arteries, and in arterioles that branch off them, and using them and differences between them to find information about the equivalent inner diameter of said arterioles, and/or about changes in said diameter of the arterioles.

Abstract: Methods to identify and risk stratify disease states, cardiac structural defects, functional cardiac deficiencies induced by teratogens and other toxic agents, pathological substrates, conduction delays and defects, and ejection fraction using single channel biological data obtained from the subject. A modified Matching Pursuit (MP) algorithm may be used to find a noiseless model of the data that is sparse and does not assume periodicity of the signal. After the model is derived, various metrics and subspaces are extracted to characterize the cardiac system. In another method, space-time domain is divided into a number of regions (which is largely determined by the signal length), the density of the signal is computed in each region and input to a learning algorithm to associate them to the desired cardiac dysfunction indicator target.

Abstract: A portable apparatus includes a housing, the apparatus includes: a heart activity sensor configured to measure heart activity measurement data related to a user carrying out a physical exercise; a communication circuitry configured to provide the portable apparatus with wireless communication capability; a memory unit configured to store an audio track; and a processing circuitry configured to receive configuration data from an external user interface apparatus over the bidirectional wireless communication connection established through the communication circuitry. The received configuration data includes control data controlling audio playback of the audio track to process and play the audio track according to the received configuration data. The portable apparatus includes a support structure that enables attachment of the portable apparatus to a body of the user.

Abstract: A magnetic resonance imaging (MRI) system, method and/or computer readable storage medium is configured to effect QISS (quiescent interval single shot) MR imaging (e.g., MR angiography or MRA) where an optimized flip angle for one or more initial saturation pulses minimizes background signal from tissue and/or venous blood. Upon expiration of first configurable time interval from a start of a scan interval, at least one saturation pulse having a flip angle greater than ninety degrees is applied so that longitudinal magnetization of background tissue and venous blood in the selected area is approximately at a null value at the beginning of a readout time (occurring upon expiry of a second time interval) and/or when a lowest frequency of k-space data is acquired for the selected area.

Abstract: Elicited MRI signals are processed into MR image data in conjunction (a) with use of an initial spatially-selective RF tag pulse (tag-on) and (b) without use of an initial spatially-selective NMR RF tag pulse (tag-off) in respectively corresponding data acquisition subsequences. Multi-dimensional tag-on and tag-off data acquisition subsequences are used for each of plural time-to-inversion (TI) intervals without using an injected contrast agent. Acquired image data sets are subtracted for each TI interval to produce difference values as a function of time representing blood perfusion for the ROI that differentiates between normal, ischemic and infarct tissues.

Abstract: A blood pressure cuff includes a first bladder having a width, and a length transverse to the width. The blood pressure cuff also includes a second bladder connected to the first bladder and a port fluidly connected to at least one of the first and second bladders.

Abstract: Hardware and software methodology are described for cardiac health measurement. Hemodynamic waveforms variously acquired for a subject are analyzed to calculate or approximate intrinsic frequencies in two domains in two domains across the Dicrotic Notch. The intrinsic frequencies provide metrics/measures that correlate to the cardiac health of the subject. The systems may be used for monitoring a condition and/or is diagnosis. Exemplary uses include identifying (diagnosing) the presence of arrhythmia, heat failure, atrial fibrillation, aneurysms, vessel stenosis or aortic valve dysfunction and the necessity for valve replacement and/or monitoring congestive heart failure progression, together with identifying the acute need for hospitalization in connection with daily testing for any such condition.

Abstract: In one embodiment, a cardiovascular condition is diagnosed by recording a vectorcardiogram for a subject under evaluation, comparing the vectorcardiogram with vectorcardiograms of other subjects, and diagnosing the subject under evaluation based upon the comparison.

Abstract: Implantable systems and methods directed toward improved accuracy in cardiac signal analysis. An impedance waveform is captured and used to confirm the analysis performed by the system on electrical signals or electrocardiogram. A detected heart beat from the electrocardiogram is either confirmed or identified as a misdetection depending on whether the impedance waveform shows likely correct or incorrect detection. Identified misdetection can then be corrected or otherwise mitigated.

Abstract: Techniques for evaluating cardiac electrical dyssynchrony are described. In some examples, an activation time is determined for each of a plurality of torso-surface potential signals. The dispersion or sequence of these activation times may be analyzed or presented to provide variety of indications of the electrical dyssynchrony of the heart of the patient. In some examples, the locations of the electrodes of the set of electrodes, and thus the locations at which the torso-surface potential signals were sensed, may be projected on the surface of a model torso that includes a model heart. The inverse problem of electrocardiography may be solved to determine electrical activation times for regions of the model heart based on the torso-surface potential signals sensed from the patient.

Abstract: A method includes storing baseline data representing at least one local or global electrical characteristics for at least a portion of a region of interest (ROI) of a patient's anatomical structure. The baseline data is determined based on electrical measurement data obtained during at least one first measurement interval. The method also includes storing in memory other data representing the at least one local or global electrical characteristics for the at least a portion of the ROI based on electrical measurement data obtained during at least one subsequent measurement interval. The method also includes evaluating the baseline data relative to the other data to determine a change in the at least one local or global electrical characteristics. The method also includes generating an output based on the evaluating to provide an indication of progress or success associated with the applying the treatment.

Abstract: Methods and apparatus for identifying and using at least one nonlinear feature determined from multiscale electroencephalography (EEG) data to evaluate an epileptogenicity level of a patient is described. A multiscale algorithm is applied to EEG data recorded from the patient to produce scaled EEG data. At least one nonlinear feature value for the received EEG data and/or the scaled EEG data is determined and the at least one nonlinear feature value is used, at least in part, to evaluate the epileptogenicity level of the patient.

Abstract: The present invention relates to a neurofeedback system that comprises an electrode (2, 2?, 2?) for contacting skin (6) of a user (7) for measuring a biofeedback signal (9) of the user (7), a first signal processing unit (3) for determining a signal characteristic (11) of the measured biofeedback signal (9), wherein the signal characteristic (11) represents a neurofeedback, a second signal processing unit (4) for determining a biofeedback signal quality (12) of the measured biofeedback signal (9) by extracting a signal feature of the measured biofeedback signal (9) and calculating a probability of a measurement error for said signal feature, which probability represents the biofeedback signal quality (12), and a feedback unit (5) for providing feedback to the user, wherein the feedback comprises the neurofeedback and a feedback about the biofeedback signal quality (12).

Abstract: A method can include analyzing non-invasive electrical data for a region of interest (ROI) of a patient's anatomical structure to identify one or more zones within the ROI that contain at least one mechanism of distinct arrhythmogenic electrical activity. The method also includes analyzing invasive electrical data for a plurality of signals of interest at different spatial sites within each of the identified zones to determine intracardiac signal characteristics for the plurality of sites within each respective zone. The method also includes generating an output that integrates the at least one mechanism of distinct arrhythmogenic electrical activity for the one or more zones with intracardiac signal characteristics for the plurality of sites within each respective zone.

Abstract: Methods and systems for evaluating a subject's response to a task related to a stimulus include a brain activity sensor, such as an EEG sensor, for measuring neural data generated by the subject in response to the visual stimulus. One or more neural discriminators can be calculated based on the neural data. In order to generate one or more neural discriminators, two or more task conditions can be selected for discrimination. The subject's performance can be evaluated based on the one or more neural discriminators. Feedback can be provided to the subject to assist in achieving better performance.

Abstract: A magnetic resonance imaging sequence is defined by an imaging protocol and parameter values for a set of parameters of the imaging protocol. A contrast signal score is computed for the magnetic resonance imaging sequence respective to a contrast type to be scored using a scoring equation. A contrast type is determined for the magnetic resonance imaging sequence based on the computed contrast signal score. In one approach, the computing is repeated for a plurality of different contrast types to be scored, and the determining is based on the computed contrast signal scores.

Abstract: The disclosure relates to an electrophysiological analysis system including: a series of electrodes intended to be placed in different regions of the human body; a direct current voltage source; a control device adapted (i) to selectively apply direct current pulses, generated by the voltage source, to a pair of so-called active electrodes, the active electrodes forming an anode and a cathode, and (ii) to connect at least one other so-called passive electrode with high-impedance, the electrode measuring the potential reached by the body; and a measurement device arranged to obtain data representative of the current at the cathode and the potentials on at least some of the electrodes connected with high impedance, in response to the application of the pulses, which data can be used to determine a value for the electrochemical conductance of the skin.

Abstract: A system for spatial impedance imaging includes a multi-layer coaxial probe for spatial impedance imaging. The multi-layer coaxial probe includes: an elongated core having a distal end and a proximal end; a first coating layer wrapping around the core; a set of alternating conductive and insulating coating layers on top of said first coating layer, wherein an Nth coating layer is shorter than an N-1th coating layer beneath it. The elongated core includes a needle or other suitable elongated member.

Abstract: A device for determining the regional distribution of a parameter for lung perfusion includes an electrical impedance tomography unit with electrodes (E1, . . . EN), which can be placed on the thorax, that are connected to a control and analysis unit (2) and an administering device (4) for the intravenous administration of a conductivity contrast medium. The control and analysis unit (2) is configured to display changes in impedance distribution occurring as a consequence of the administration of conductivity contrast medium as a parameter for lung perfusion in the section plane as a function of time. The administering device (4) has a controllable dispensing device. The control and analysis unit and the dispensing device are connected with one another via a data link (3). A start time and an end time and a quantity of an administered bolus of the conductivity contrast medium are available to the control and analysis unit (2).

Abstract: A patient bed, particularly for use in a magnetic resonance (MR) imaging-guided therapy system employing at least one out of ionizing radiation and ultrasound energy for therapy purposes, having an abdominal support portion (14) for supporting an abdominal region (18) of a subject (12) during magnetic resonance-guided therapy, comprising at least one magnetic resonance (MR) radio frequency (RF) antenna device (48) arranged at a top side (26) of the patient bed in a patient bed center region (30), with at least one MR RF antenna (50) that is enclosed in a housing (52) having two side surfaces (54) opposing each other, wherein, in at least one state of operation, each side surface (54) of the MR RF antenna device (48) is provided to be proximal to an inner side of each of the subject's legs (22), and wherein, in the at least one state of operation, the MR RF antenna device (48) is provided to be proximal to a subject's perineum (20); an MR radio frequency (RF) antenna device (48) therefor; and a therapy system

Abstract: A system for providing indications of location of a catheter tip within a patient, the system including a memory storing synthesized blood pressure waveform parameters representative of a first plurality of catheter tip locations in a second plurality of representative patients, real time patient blood pressure waveform parameter acquisition circuitry operative to acquire real time blood pressure waveform parameters of a patient currently undergoing catheterization, which parameters contain information useful in ascertaining the location of a catheter tip in the patient and real time patient catheter tip location ascertaining circuitry operative to receive the real time patient blood pressure waveform parameters from the acquisition circuitry and to employ the synthesized blood pressure waveform parameters for providing a real time indication of catheter tip location in the patient.

Abstract: A guidance and placement system and associated methods for assisting a clinician in the placement of a catheter or other medical device within the vasculature of a patient is disclosed. In one embodiment, a method for guiding a medical device to a desired location within a vasculature of a patient is also disclosed and comprises detecting an intravascular ECG signal of the patient and identifying a P-wave of a waveform of the intravascular ECG signal, wherein the P-wave varies according to proximity of the medical device to the desired location. The method further comprises determining whether the identified P-wave is elevated, determining a deflection value of the identified P-wave when the identified P-wave is elevated, and reporting information relating to a location of the medical device within the patient's vasculature at least partially according to the determined deflection value of the elevated P-wave.

Abstract: Provided are systems and method for identifying, generating and displaying a trend of one or more medical waveform related features.

Abstract: A computerized method and system for measuring a user's lung capacity and stamina, to detect Chronic Heart Failure, COPD or Asthma, comprising: providing a client application on a user's mobile communication device, said client application comprising executable computer code for: instructing the user to fill his lungs with air and utter vocal sounds within a certain range of loudness (decibels) while exhaling; receiving and registering by the mobile communication device said user's vocal sounds; stopping the registering of vocal sounds; measuring the length of the vocal sounds receiving time within said range of loudness, said time proportionate the user's lung volumes; and displaying the length of sound received time results on the mobile communication device screen.