Abstract: A method is provided that includes inserting a catheter into an atrium of a subject, and deploying at least one loop from a wall of the catheter, such that a distal end of the loop is distal to a distal end of the catheter. The method further includes inserting the loop partially into an appendage of the atrium, and, while inserting the loop, atraumatically contacting a portion of a perimeter of an opening of the appendage with a portion of the loop. Thereafter, the loop is further inserted into the appendage. Thereafter, a size of the opening of the appendage is measured using the loop. Other applications are also described.

Abstract: A method of preventing ingress of material into the left atrium of a heart includes providing a delivery sheath, advancing the sheath distal end through an opening between the right atrium and the left atrium of the heart, providing an expandable cage, delivering the expandable cage to the left atrium, and expanding the expandable cage within the left atrium. The expandable cage includes a proximal end, a distal end, and a plurality of supports extending therebetween. The expandable cage also includes a first membrane provided at its proximal end and a second membrane provided at its distal end. The expandable cage has a collapsed configuration so that it can be received within the lumen of the delivery sheath, and an expanded configuration for deployment within the heart. When expanded, the first membrane is positioned at an opening between the left and right atria of the heart, and the second membrane is positioned at the ostium of the left atrial appendage.

Abstract: A system for performing minimally invasive procedures in a working space within a body lumen of a patient including a flexible catheter configured to receive a working instrument therethrough. The flexible catheter has a working space expanding system positioned at the distal portion, the working space expanding system including first and second flexible elements movable from a non-expanded insertion position to an expanded position forming an expanded region to expand the working space within the body. The first and second flexible elements are connected at a distal region by a coupling structure. A stabilizing member stabilizes the distal portion of the flexible catheter.

Abstract: A distracting portal device for use between two adjacent vertebrae during an intervertebral surgical procedure. The distracting portal device is a three-dimensional object having a two-dimensional cross-section extended into a third dimension, where the cross-section has a shape which defines one or two portal openings. Each portal opening creates a space between the vertebrae into which a surgeon has clear access to perform the surgical procedure, such as a discectomy. Opposing top and bottom surfaces of the portal device are configured for contact with and distraction of the two adjacent vertebrae. The portal device is selected from a family having a single portal opening and having a cross-section resembling one of the letters “C”, “O” or “U”, or a family having two portal openings and having a cross-section resembling one of the letters “H” or “I”.

Abstract: An expandable trial can include an inferior portion, a superior portion, and a middle expanding portion as well as load cells for monitoring the load on the trial. The trial may also include recesses on its lateral sides to provide spacing to accommodate a disc removal tool so tissue can be cleared monitoring load. In addition, neural foramen spacing can be monitoring to provide information about how much neural release has been achieved as the disc is cleaned and the spine is positioned and repositioned.

Abstract: The present disclosure relates to a suture anchor. The suture anchor includes a body having a proximal end and a distal end, the body including threads along at least a partial length of the body and at least one through hole, the threads including a profile such that the threads located near the distal end of the body include a first shape and the threads located near the proximal end of the body include a second shape different from the first shape. Delivery devices and anchor dilators are also disclosed.

Abstract: Soft anchor constructs and methods for soft tissue to bone repairs. The soft anchors may be knotted or knotless constructs. The soft anchors include a body formed of various soft materials (including, but not limited to, suture) and provided in various shapes and configurations that confer the anchors the ability to be easily inserted within bone tunnels or sockets and be bunched up within the bone tunnels or sockets. At least one closed loop or soft eyelet is attached to the soft anchor to allow additional sliding strands and/or shuttle/pull devices (suture passing devices) to pass through the eyelet and aid in the knotted or knotless fixation of tissue to bone.

Abstract: A medical fastening device is provided. The fastening device may include a first arcuate needle adapted to rotate about a first axis in a first direction, entering through a first section of one of a tissue and a prosthetic material, and exiting through a second section of one of the tissue and the prosthetic material; a second arcuate needle adapted to rotate about a second axis in a second direction, entering through the second section of one of the tissue and the prosthetic material, and exiting through the first section of one of the tissue and the prosthetic material; and a drive mechanism operatively coupled to each of the first and second arcuate needles and configured to engage each of the first and second arcuate needles between a retracted position and an extended position.

Abstract: A surgical stapling instrument includes a handle having a stapler-closing device. A surgical stapling end effector is connected to the handle and has a pair of opposing stapling surfaces. At least one of the stapling surfaces is operable to move with respect to the other of the stapling surfaces upon actuation of the stapler-closing device to apply a compressive force to tissue therebetween. At least one variable member is operable to receive the compressive force applied to the tissue and to exhibit at least one of mechanical and electrical change associated with the received compressive force. The change influences a surgical procedure on the compressed tissue.

Abstract: A surgical instrument includes a body, a shaft assembly, a stapling head assembly, an anvil, an anvil adjustment assembly, a trigger, and a lockout assembly. The stapling head assembly is operable to drive an annular array of staples. The anvil is configured to couple with the stapling head assembly. The anvil adjustment assembly includes a translating member, which translates relative to the body to thereby adjust the longitudinal position of the anvil relative to the stapling head assembly. The trigger is operable to actuate the stapling head assembly to thereby drive the annular array of staples through a distal surface of the stapling head assembly toward the anvil. The lockout assembly includes an electrically powered braking feature. In a first state, the lockout assembly is configured to permit translation of the translating member. In a second state, the lockout assembly is configured to prevent translation of the translating member.

Abstract: A method for resetting an apparatus configured for stapling tissue includes providing the apparatus with a cam member of the apparatus in a fired position. The method further includes changing the polarity of a motor of the apparatus and activating the motor such that the cam member rotates in a second direction from the fired position back to a home position. The apparatus further includes a stapling head assembly and a shaft assembly coupled to the stapling head assembly. The apparatus further includes a body coupled to the shaft assembly. The body comprises a motor and a cam member that is configured to rotate in response to activation of the motor. Rotation of the cam member in a first direction from the home position to the fired position results in actuation of the stapling head assembly.

Abstract: A surgical circular stapler has a handle assembly, a shaft, a stapling assembly, and a firing assembly. The shaft extends distally from the handle assembly. The stapling assembly is secured to a distal end of the shaft. Longitudinal translation of the firing assembly causes the stapling assembly to drive a plurality of staples in a circular array to secure two lumens of tissue together. The stapling assembly may further drive a blade to sever any excess tissue interior of the circular array of staples. The stapler further includes a lockout assembly configured to control firing of the stapling assembly. The lockout assembly may include one or more switches, the actuation of which is configured to prevent or permit firing of the stapling assembly. The lockout assembly may additionally or alternatively include one or more mechanical lockout features configured to control firing of the stapling assembly.

Abstract: A surgical instrument includes a stapling head assembly, an anvil, a firing assembly, a load sensor, and an indicator. The firing assembly actuates the stapling head assembly to drive an annular array of staples through tissue toward the anvil. The load sensor is operable to sense a load in the firing assembly while the firing assembly actuates the stapling head assembly. The indicator is operable to provide feedback based on the load sensed by the load sensor. The firing assembly may include a longitudinally translatable member. The instrument may further include a position sensor that is operable to sense a longitudinal position of the translatable member while the firing assembly actuates the stapling head assembly. The indicator may be activated based on data from at least one of the sensors indicating completion or failure of a full actuation stroke of the firing assembly.

Abstract: A surgical instrument includes an anvil, a staple applying assembly, an adjustment member, a user input feature, and a bailout assembly. The staple applying assembly includes a distal surface defining openings and a driver that is operable to drive an annular array of staples through the openings of the distal surface and into tissue. The adjustment member is operable to adjust the position of the anvil to thereby vary a gap distance defined between the anvil and the distal surface. The adjustment member includes a first section and a second section. The user input feature is operable to actuate the driver to thereby drive the staples. The bailout assembly is operable to selectively separate the first section of the adjustment member from the second section of the adjustment member.

Abstract: A surgical instrument for stapling tissue includes a body, a shaft assembly, and an anvil. The shaft assembly includes a stapling head assembly and an actuator. The anvil is configured to be selectively coupled to the actuator. The anvil is configured to cooperate with the stapling head assembly to staple tissue. The anvil comprises a head and a shank extending from the head. The shank includes a proximal end, a distal end, a lumen, and an engagement feature. The engagement feature is in communication with the lumen such that the engagement feature is configured to move relative to the axis in response to the rod being directed into the lumen. The engagement feature is configured to selectively couple the shank to the actuator. The proximal end of the engagement feature is radially fixed relative to the axis.

Abstract: A surgical instrument includes a stapling head assembly, an anvil, an anvil adjustment assembly, and an indicator assembly. The anvil is configured to couple with the stapling head assembly. The anvil adjustment assembly includes a translating member, which is operable to translate relative to the body to thereby adjust a gap distance between the anvil and a distal surface of the stapling head assembly. The indicator assembly includes a first member and a second member. The first member is configured to translate in response to translation of the translating member relative to the body. The second member is configured to remain stationary relative to the body. The indicator assembly is configured to provide feedback indicating whether the gap distance is sized to release tissue from between the anvil and the distal surface based on positioning of the first member in relation to the second member.

Abstract: A surgical instrument includes a body, a shaft assembly, a stapling head assembly, an anvil, an anvil adjustment assembly, a trigger, and a lockout assembly. The stapling head assembly is operable to drive an annular array of staples. The anvil is configured to couple with the stapling head assembly. The anvil adjustment assembly includes a translating member, which translates relative to the body to thereby adjust the longitudinal position of the anvil relative to the stapling head assembly. The trigger is operable to actuate the stapling head assembly. The lockout assembly includes an electrically powered braking feature. A method of operating the surgical instrument includes providing the lockout assembly in a first state to permit translation of the translating member. The translating member is then translated. The lockout assembly is then transitioned to a second state to prevent further translation of the translating member.

Abstract: A surgical instrument includes a stapling head assembly, an anvil, a firing assembly, a motor, a user input feature, and an electrical circuit. The firing assembly actuates the stapling head assembly to drive an annular array of staples through tissue toward the anvil. The motor actuates the firing assembly through an actuation stroke to thereby actuate the stapling head assembly. The electrical circuit includes a trigger switch and an electrical latching feature. The trigger transitions from an open state to a closed state in response to the user input feature transitioning from a non-actuated state to an actuated state. The electrical circuit activates the motor in response to closure of the trigger switch. The electrical latching feature maintains activation of the motor to complete the actuation stroke even if the trigger switch is transitioned back to the open state before completion of the actuation stroke.

Abstract: A tissue anchor includes an elongated body having a proximal end and a distal end, and a barb mounted to the elongated body adjacent the proximal end for movement between a retracted position and an extended position in which the barb projects outwardly from the elongated body. An anchoring system includes an implantable device with a tissue contacting surface facing in a proximal direction, the tissue anchor having its distal end engageable with the implantable device and its proximal end adapted to project proximally beyond the tissue contacting surface to grip a living tissue, and a second resilient element that is mounted between the distal end of the anchor and the implantable device, the second resilient element being adapted to bias the anchor distally relative to the implantable device. Tooling and methods of insertion and removal are provided.

Abstract: A surgical severing and stapling instrument, suitable for laparoscopic and endoscopic clinical procedures, clamps tissue within an end effector of an elongate channel pivotally opposed by an anvil. An E-beam firing bar moves distally through the clamped end effector to sever tissue and to drive staples on each side of the cut. The E-beam firing bar affirmatively spaces the anvil from the elongate channel to assure properly formed closed staples, especially when an amount of tissue is clamped that is inadequate to space the end effector. In particular, an upper pin of the firing bar longitudinally moves through an anvil slot and a channel slot is captured between a lower cap and a middle pin of the firing bar to assure a minimum spacing. Forming the E-beam from a thickened distal portion and a thinned proximal strip enhances manufacturability and facilitates use in such articulating surgical instruments.

Abstract: A method of controlling a surgical stapler system includes transmitting an actuation force to a staple cartridge to actuate a staple firing procedure, the staple cartridge being removably received by a portion of an end effector of a surgical instrument, measuring the transmitted actuation force, and controlling continued transmission of the actuation force based on a comparison of the measured actuation force to a range defined from a minimum threshold actuation force to a maximum threshold actuation force.

Abstract: An anvil assembly for use therewith a surgical fastener applying apparatus including an anvil plate and an anvil head configured and dimensioned to support the anvil plate. The anvil plate and the anvil head may be formed from different materials. The anvil plate can include a tapered outer side wall allowing the anvil assembly to realize a substantially uniform proximal-most surface upon assembly.

Abstract: A surgical stapler is provided that includes a spring loaded lift that automatically adjusts a staple cartridge and/or staple formation between a range of sizes. The lift is automatically released as the staple firing mechanism begins its forward translation of the firing sequence. The automatic one-way adjustment also adjusts the staple cartridge while maintaining the cartridge parallel to the anvil to provide consistent staple formations.

Abstract: A surgical stapling apparatus includes a staple cartridge and an anvil member. The staple cartridge includes a plurality of surgical fasteners disposed in rows of retention slots. The staple cartridge may have an annular or linear configuration of retention slots. The tissue contacting surface of the staple cartridge may be tapered or stepped. The anvil member has a tissue contacting surface that includes a number of pockets arranged for substantially aligning with the retention slots. In addition, the tissue contacting surface of the anvil member may complement the tissue contacting surface of the staple cartridge.

Abstract: A surgical fastener applying apparatus having a first jaw and a second jaw. The first jaw includes a cartridge body having plurality of surgical fasteners disposed therein. The plurality of surgical fasteners include a plurality of first surgical fasteners having a first backspan with a first configuration, and a plurality of second surgical fasteners having a second backspan with a second, different configuration such that the plurality of first surgical fasteners apply a first compressive force to tissue upon formation and the plurality of second surgical fasteners apply a second, different compressive force to tissue upon formation.

Abstract: A surgical circular stapler has a handle assembly, a shaft, a stapling assembly, and a firing assembly. The shaft extends distally from the handle assembly. The stapling assembly is secured to a distal end of the shaft. Longitudinal translation of the firing assembly causes the stapling assembly to drive a plurality of staples in a circular array to secure two lumens of tissue together. The stapling assembly may further drive a blade to sever any excess tissue interior of the circular array of staples. The stapler further includes an indicator configured to indicate “readiness” of the stapler and/or to control firing of the stapling assembly. The indicator may indicate a position of an anvil relative to the stapling assembly and/or coupling of the anvil to the stapling assembly among other things. In addition, the stapler may include a self-draining battery pack configured to drain power upon removal from the stapler.

Abstract: The creation of arteriovenous fistulas in renal dialysis patients is associated with various problems. By placing a valve which can control the blood flow between artery and vein, material improvements in renal dialysis patient care can be achieved. In a preferred embodiment, the valve is mounted on a ring located around an aperture in the side of an asymmetrically expanded stent set in the artery. Novel stents, valve structures and valve ring insertion arrangements are also described.

Abstract: A system and method for endoscopically forming an anastomosis between two naturally adjacent points in the digestive tract. The system and method utilizes elongate magnetic devices that, when connected across a tissue boundary, necrose tissue until an anastomosis forms and the devices are passed naturally. Despite the elongate shape of the devices, the resulting anastomosis is substantially round. As such, round anastomoses can be formed having increased diameters merely by increasing the lengths of the devices, obviating the need for wider endoscopes.

Abstract: A surgical instrument includes a body, a shaft assembly, a stapling head assembly, and a drive assembly. The shaft assembly includes an actuator. The stapling head assembly is operable to drive an annularly arranged array of staples into tissue in response to translation of the actuator along a first axis relative to the body. The drive assembly is operable to translate the actuator along the first axis. The drive assembly comprises first and second rotary members. The first rotary member is rotatable about a second axis. The second axis is non-parallel with the first axis. The second rotary member is rotatable about a third axis. The third axis is non-parallel with the first axis and non-parallel with the second axis. The first rotary member is operable to drive the second rotary member to rotate about the third axis to thereby drive the actuator along the first axis.

Abstract: A surgical implant comprising a receiver member and deployment member for clamping and sealing tissue of variable thickness, a corresponding applicator tool and surgical system for connecting, sealing, fastening and/or attaching tissue to itself, to other tissue and/or to non-tissue structures, and/or sealing the flow of fluid at and/or between structures such as tissue and vessel structures.

Abstract: Aspects of the present disclosure are directed toward providing enhanced structural support to an organ. As may be implemented in accordance with one or more embodiments, an apparatus includes structure configured and arranged to partially encircle a tubular organ, having a semi-cylindrical shape with a tapered end and blunt end of the cylinder. A gap region provides a region of the organ that is unrestricted/unsupported. Struts/lattice facilitate ingrowth of tissue, and couple the apparatus to the organ, which allows the apparatus to provide support/restrict flow in the organ without necessarily coupling to any other structure (e.g., with the majority or all of the support provided via the apparatus as coupled onto and terminating on a sidewall of the tubular organ).

Abstract: Medical device including an artificial contractile structure including at least one contractile element adapted to contract a hollow body organ, in such a way that the contractile element is adapted to be in a resting position or in an activated position, the activated position being defined with the contractile element constricting the hollow body organ and the resting position being defined with said contractile element not constricting the hollow body organ. The medical device can include a tensioning device adapted to apply a force so as to tighten the contractile element around said hollow body organ. The tensioning device can be arranged to cause the contractile element to apply a substantially uniform occlusive pressure of at most 8N/cm2, along the circumference of the contact area between the contractile element and the hollow body organ when the contractile element is in its activated position.

Abstract: A multiple band endoscopic ligation device comprises a single pull string and a plurality of beads positioned on said pull string and between each successive band. The device is configured to be coupled to the distal end of an endoscope and is used to deploy multiple elastic bands around target tissues to be ligated. The device includes a tapered cylindrical body about which a plurality of elastic bands are stretched and positioned. The pull string includes multiple sets of two beads fixed to the string wherein one bead is placed directly behind and in contact with the other. The string is wrapped around the device's body and under each band such that at least one pair of beads is positioned between the elastic bands and one pair of beads is positioned proximally to the most proximal band. As the string is pulled, the beads push the bands sequentially off the distal end of the device and around a tissue to be ligated.

Abstract: A device for mechanically reducing the volume of a lung, comprising a distal anchor, a proximal anchor, and a tether extending between the distal and proximal anchors, the device configured so that the distance between the anchors measured along the tether can be increased or decreased and maintained after release of a delivery device. Some embodiments are a method of endobronchially deploying an anchoring device within the lung to reduce the lung volume, the anchoring device comprising a distal anchor, a proximal anchor, and a tether extending between the distal and proximal anchors, the device configured such that the distance between the distal and proximal anchors measured along the tether can be increased or decreased and then maintained after release of the anchoring device from a delivery device, reducing the volume of the lung by decreasing the distance between the distal and proximal anchors, and maintaining the decreased distance.

Abstract: This invention is a device to occlude a cerebral aneurysm which includes: a longitudinal lumen that is inserted into the parent blood vessel of an aneurysm; a flexible expandable member (such as a net or mesh) which is expanded within the aneurysm sack by the insertion of embolic members into that flexible expandable member; and a resilient expandable member (such as a cylindrical stent or ring stent) that is attached to a central portion of the flexible expandable member and expanded within the aneurysm sack in order to keep the flexible expandable member from slipping out of the aneurysm sack.

Abstract: A posterior stabilized cruciate notch femoral cut guide shaped to fit over the distal end of a femur and including various cut guides to prepare the femur for a knee implant and methods for its use. Also described is a method for manufacturing the posterior stabilized cruciate notch femoral cut guide and various other cut guides and trialing instruments.

Abstract: A femoral component (2) of a knee joint prosthesis has a bearing surface (4) for articulation with a tibial bearing surface and an opposite bone facing surface (6). The bone facing surface has anterior (18), posterior (20), distal (22), anterior chamfer (24) and posterior chamfer (26) portions. Medial (42, 52, 356) and lateral rails (40, 50, 350) are provided on the distal portion or on at least one of the anterior chamfer portion and posterior chamfer portions of the bone facing surface so that there is at least one recess (46, 54, 354, 360) between the rails.

Abstract: A method of attaching prosthetic implants to bone, applicable to tibia, patella, acetabulum, glenoid, or femur, includes trimming an articular surface of the bone, leaving a trimmed surface. Holes are punched or drilled into the surface in a predetermined array before polymethyl methacrylate bone cement is used to attach the surface to the implant. In an embodiment, the holes are punched by placing a punch-plate with sharpened punch spikes on the surface, and striking the punch plate to drive punches into the trimmed surface. In another embodiment, holes are drilled using a drilling template with predrilled guidance holes placed on the surface of the bone. In another embodiment, holes are drilled by positioning a robotic drill over the trimmed surface; adjusting a drilling pattern of the robotic drill according to the trimmed surface; and using the robotic drill to drill holes of predetermined depth according to the drilling pattern.

Abstract: Embodiments of the invention include a system and method for coupling a graft to a bone. A graft preparation tool may be used to place one or more holes in a graft and an offset measurement tool may be used to determine the distance of the one or more holes from an edge of the graft to be aligned with a portion of the bone. One or more complementary holes may then be created in the bone and fasteners applied through the holes to couple the graft to the bone.

Abstract: Implant devices and cutting clamp apparatuses and methods for creating the implants for insertion into a patient's joint to restore anatomic length and assist in final positioning of the bones following removal of cartilage and/or bone in preparation for fusion. A first implant is a biplanar implant having a shape to mimic the normal anatomical shape of the bones the implant is configured to mate with. The first implant may be cut using a cutting clamp and jig having the anatomical shape of the bones the implant will be inserted within or between. A second implant is a cylindrical piece of bone having a convex end and a concave end for mating with bones reamed to have the opposite mating surfaces. The second implant is created using cup and cone reamers having dimensions corresponding to the size of the patient's bones. Surgical methods for inserting the implants within a patient.

Abstract: A humeral cut guide member for resectioning or resurfacing a humeral head, including a bone-engagement member including a first patient-specific bone-engagement surface that is complementary and made to substantially mate and nest in only one position on a specific patient's humeral head; a registration member connected to the bone-engagement member including a second patient-specific bone engagement surface that is sized and made to substantially mate and nest in only one position with the specific patient's bicipital groove; and a cut guide plate connected to the bone-engagement member and defining an elongated slot.

Abstract: A humeral cut guide system for a humeral head comprises: a bone-engagement member including a first patient-specific bone-engagement surface that is complementary and made to substantially mate and nest in only one position on a specific patient's humeral head; a registration member connected to the bone-engagement member including a second patient-specific bone engagement surface that is sized and made to substantially mate and nest in only one position with the specific patient's bicipital groove; a first protrusion extending from the registration member and having a first surgeon-engaging surface for manipulation by a surgeon; and a cut guide plate connected to and extending away from the registration member such that, upon the bone-engagement member mating and nesting with the specific patient's humeral head, the cut guide plate is spaced apart from the humeral head, wherein the cut guide plate defines an elongate slot.

Abstract: Disclosed are devices, methods and/or systems for tissue protectors and/or retractors having patient specific and/or patient adapted features that facilitate the accuracy and predictability of bone resection and tissue preparation during joint surgery, as well as improve the distraction of soft tissues, desirably preventing accidental injury to surrounding soft tissue structures and improving visualization.

Abstract: A set of instruments for preparing a femur and tibia for receipt of a partial knee prosthesis can include a femoral drill guide that is selectively connected to an intramedullary (IM) rod. At least one sizing spoon can communicate with the femoral drill guide. The femoral drill guide can have terminal cutting surfaces. A tibial cut guide can be selectively connected to the femoral drill guide. A dial member can be disposed on one of the femoral or tibial cut guides that when rotated moves at least one of the spoons in a superior/inferior direction.

Abstract: The present specification discloses an endoscope device comprising a body having a proximal opening in communication with an opposite distal opening, and the body having a nose substantially about the distal opening, a primary lumen or blockage receiving lumen formed within the body through which suction is selectively applied, the primary lumen being contiguous with the distal opening, and a secondary lumen or endoscope receiving lumen formed within the body so as to be in communication with the primary lumen, the secondary lumen being contiguous with the proximal opening and configured for receipt of an endoscope, whereby suction applied through a suction port of the endoscope when positioned in the secondary lumen applies suction to the primary lumen.

Abstract: A catheter having a distal balloon and a deformable guidewire shaft of the catheter. The deformable guidewire shaft is adjacent to and external to the balloon. Inflation of the balloon bends the deformable guidewire shaft in order to orient or deflect a distal tip of the deformable guidewire shaft in a desired direction to guide and direct a guidewire extending through the deformable guidewire shaft towards a specific endovascular region. For example, it may be desired to orient the distal tip of the guidewire shaft towards a target vessel of a bifurcation or the balloon catheter may be used to bypass a Chronic Total Occlusion (CTO).

Abstract: A stone retrieval device includes a sheath and a stone retrieval basket that includes a distal region with a plurality of basket wires and a proximal region with one or more core wires. The stone retrieval basket is contained within the sheath and is movable out a distal opening of the sheath to cause the plurality of basket wires to open into a basket shape. The stone retrieval device further includes a lock mechanism that locks the position of the stone retrieval basket with respect to the position of the sheath and a basket force controller that includes a first control stage and a second control stage. The first control stage includes a sensor for measuring force on the stone retrieval basket when the lock mechanism is in an unlocked position, and the second control stage includes a sensor for measuring force on the stone retrieval basket when the lock mechanism is in a locked position.

Abstract: According to various embodiments, there is provided a thrombolysis device including a catheter configured to be inserted into a blood clot; a treatment transducer coupled to the catheter, the treatment transducer configured to transmit acoustic waves; a measurement transducer coupled to the catheter, the measurement transducer configured to transmit further acoustic waves and further configured to receive acoustic echoes, the acoustic echoes being reflections of the further acoustic waves from a boundary of the blood clot, wherein the measurement transducer is further configured to provide a measurement output; a determination circuit configured to determine at least one of a viscosity of blood in a vicinity of the measurement transducer or a volume of the blood clot, based on the measurement output; and a control circuit configured to generate control signals for controlling the treatment transducer, based on at least one from the group consisting of the viscosity of blood in the vicinity of the measurement

Abstract: Systems and methods are provided to enable distribution of skin particles to a target site, for example, a wound site. Related kits are also provided.

Abstract: An aspiration control device may include a conduit having a distal end and a proximal end and defining a conduit lumen, wherein the conduit defines a vent that is open to the conduit lumen, a coupling configured to couple the proximal end of the conduit with a vacuum source and an inner cannula such that a vacuum is supplied to each of the conduit lumen and the inner cannula, a sleeve movably disposed about the conduit and configured to move relative to the vent to achieve a desired level of vacuum delivered to the inner cannula.