Patents Issued in December 5, 2019
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Publication number: 20190364816Abstract: According to the invention, there is provided seed and plants of the hybrid corn variety designated CH455530. The invention thus relates to the plants, seeds and tissue cultures of the variety CH455530, and to methods for producing a corn plant produced by crossing a corn plant of variety CH455530 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH455530.Type: ApplicationFiled: May 30, 2018Publication date: December 5, 2019Inventors: Christian J. Buffard, Jeffrey M. Sernett, Gary R. Stangland
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Publication number: 20190364817Abstract: According to the invention, there is provided seed and plants of the hybrid corn variety designated CH532783. The invention thus relates to the plants, seeds and tissue cultures of the variety CH532783, and to methods for producing a corn plant produced by crossing a corn plant of variety CH532783 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH532783.Type: ApplicationFiled: May 30, 2018Publication date: December 5, 2019Inventors: Christian J. Buffard, Jeffrey M. Sernett, Gary R. Stangland
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Publication number: 20190364818Abstract: According to the invention, there is provided seed and plants of the hybrid corn variety designated CH177362. The invention thus relates to the plants, seeds and tissue cultures of the variety CH177362, and to methods for producing a corn plant produced by crossing a corn plant of variety CH177362 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH177362.Type: ApplicationFiled: May 30, 2018Publication date: December 5, 2019Inventors: Jorge Moran, Brett A. Ochs
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Publication number: 20190364819Abstract: According to the invention, there is provided seed and plants of the hybrid corn variety designated CH379427. The invention thus relates to the plants, seeds and tissue cultures of the variety CH379427, and to methods for producing a corn plant produced by crossing a corn plant of variety CH379427 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH379427.Type: ApplicationFiled: May 30, 2018Publication date: December 5, 2019Inventors: Fufa H. Birru, Christian J. Buffard, Richard G. Stelpflug
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Publication number: 20190364820Abstract: According to the invention, there is provided seed and plants of the hybrid corn variety designated CH265634. The invention thus relates to the plants, seeds and tissue cultures of the variety CH265634, and to methods for producing a corn plant produced by crossing a corn plant of variety CH265634 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH265634.Type: ApplicationFiled: May 31, 2018Publication date: December 5, 2019Inventors: Fufa H. Birru, Christian J. Buffard, Richard G. Stelpflug
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Publication number: 20190364821Abstract: According to the invention, there is provided seed and plants of the hybrid corn variety designated CH699413. The invention thus relates to the plants, seeds and tissue cultures of the variety CH699413, and to methods for producing a corn plant produced by crossing a corn plant of variety CH699413 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH699413.Type: ApplicationFiled: May 31, 2018Publication date: December 5, 2019Inventor: Peter Konczol
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Publication number: 20190364822Abstract: According to the invention, there is provided seed and plants of the hybrid corn variety designated CH350667. The invention thus relates to the plants, seeds and tissue cultures of the variety CH350667, and to methods for producing a corn plant produced by crossing a corn plant of variety CH350667 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH350667.Type: ApplicationFiled: May 31, 2018Publication date: December 5, 2019Inventors: Christian J. Buffard, Jeffrey M. Sernett, Gary R. Stangland
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Publication number: 20190364823Abstract: According to the invention, there is provided seed and plants of the hybrid corn variety designated CH335633. The invention thus relates to the plants, seeds and tissue cultures of the variety CH335633, and to methods for producing a corn plant produced by crossing a corn plant of variety CH335633 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH335633.Type: ApplicationFiled: May 31, 2018Publication date: December 5, 2019Inventors: Rafael A. Mateo, Richard G. Stelpflug
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Publication number: 20190364824Abstract: According to the invention, there is provided seed and plants of the hybrid corn variety designated CH384645. The invention thus relates to the plants, seeds and tissue cultures of the variety CH384645, and to methods for producing a corn plant produced by crossing a corn plant of variety CH384645 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH384645.Type: ApplicationFiled: May 31, 2018Publication date: December 5, 2019Inventors: Brett A. Ochs, Slobodan Trifunovic
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Publication number: 20190364825Abstract: According to the invention, there is provided seed and plants of the hybrid corn variety designated CH699670. The invention thus relates to the plants, seeds and tissue cultures of the variety CH699670, and to methods for producing a corn plant produced by crossing a corn plant of variety CH699670 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH699670.Type: ApplicationFiled: May 31, 2018Publication date: December 5, 2019Inventors: Fufa H. Birru, Rafael A. Mateo, Richard G. Stelpflug
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Publication number: 20190364826Abstract: According to the invention, there is provided seed and plants of the hybrid corn variety designated CH514453. The invention thus relates to the plants, seeds and tissue cultures of the variety CH514453, and to methods for producing a corn plant produced by crossing a corn plant of variety CH514453 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH514453.Type: ApplicationFiled: May 31, 2018Publication date: December 5, 2019Inventors: Fufa H. Birru, Christian J. Buffard, Jeffrey M. Sernett
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Publication number: 20190364827Abstract: According to the invention, there is provided seed and plants of the hybrid corn variety designated CH272932. The invention thus relates to the plants, seeds and tissue cultures of the variety CH272932, and to methods for producing a corn plant produced by crossing a corn plant of variety CH272932 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH272932.Type: ApplicationFiled: May 31, 2018Publication date: December 5, 2019Inventors: Rafael A. Mateo, Richard G. Stelpflug
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Publication number: 20190364828Abstract: According to the invention, there is provided seed and plants of the hybrid corn variety designated CH489160. The invention thus relates to the plants, seeds and tissue cultures of the variety CH489160, and to methods for producing a corn plant produced by crossing a corn plant of variety CH489160 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH489160.Type: ApplicationFiled: May 31, 2018Publication date: December 5, 2019Inventors: Christian J. Buffard, Jeffrey M. Sernett, Gary R. Stangland
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Publication number: 20190364829Abstract: According to the invention, there is provided seed and plants of the hybrid corn variety designated CH490143. The invention thus relates to the plants, seeds and tissue cultures of the variety CH490143, and to methods for producing a corn plant produced by crossing a corn plant of variety CH490143 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH490143.Type: ApplicationFiled: May 31, 2018Publication date: December 5, 2019Inventors: Gregory J. Holland, Duane A. Potrzeba, Jeffrey M. Sernett, Gary R. Stangland
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Publication number: 20190364830Abstract: According to the invention, there is provided seed and plants of the hybrid corn variety designated CH401605. The invention thus relates to the plants, seeds and tissue cultures of the variety CH401605, and to methods for producing a corn plant produced by crossing a corn plant of variety CH401605 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH401605.Type: ApplicationFiled: May 31, 2018Publication date: December 5, 2019Inventors: Sandeep Bhatnagar, Brett A. Ochs
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Publication number: 20190364831Abstract: According to the invention, there is provided seed and plants of the hybrid corn variety designated CH405760. The invention thus relates to the plants, seeds and tissue cultures of the variety CH405760, and to methods for producing a corn plant produced by crossing a corn plant of variety CH405760 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH405760.Type: ApplicationFiled: May 31, 2018Publication date: December 5, 2019Inventors: Sandeep Bhatnagar, Gregory J. Holland, Duane A. Potrzeba
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Publication number: 20190364832Abstract: According to the invention, there is provided seed and plants of the hybrid corn variety designated CH502484. The invention thus relates to the plants, seeds and tissue cultures of the variety CH502484, and to methods for producing a corn plant produced by crossing a corn plant of variety CH502484 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH502484.Type: ApplicationFiled: May 31, 2018Publication date: December 5, 2019Inventors: Gregory J. Holland, Duane A. Potrzeba, Jeffrey M. Sernett, Gary R. Stangland
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Publication number: 20190364833Abstract: According to the invention, there is provided seed and plants of the hybrid corn variety designated CH907499. The invention thus relates to the plants, seeds and tissue cultures of the variety CH907499, and to methods for producing a corn plant produced by crossing a corn plant of variety CH907499 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH907499.Type: ApplicationFiled: May 31, 2018Publication date: December 5, 2019Inventors: Gregory J. Holland, Duane A. Potrzeba, Jeffrey M. Sernett, Gary R. Stangland
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Publication number: 20190364834Abstract: According to the invention, there is provided seed and plants of the hybrid corn variety designated CH265916. The invention thus relates to the plants, seeds and tissue cultures of the variety CH265916, and to methods for producing a corn plant produced by crossing a corn plant of variety CH265916 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH265916.Type: ApplicationFiled: May 31, 2018Publication date: December 5, 2019Inventors: Rafael A. Mateo, Richard G. Stelpflug
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Publication number: 20190364835Abstract: According to the invention, there is provided seed and plants of the hybrid corn variety designated CH341684. The invention thus relates to the plants, seeds and tissue cultures of the variety CH341684, and to methods for producing a corn plant produced by crossing a corn plant of variety CH341684 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH341684.Type: ApplicationFiled: May 31, 2018Publication date: December 5, 2019Inventors: Christian J. Buffard, Jeffrey M. Sernett, Gary R. Stangland
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Publication number: 20190364836Abstract: According to the invention, there is provided seed and plants of the hybrid corn variety designated CH532226. The invention thus relates to the plants, seeds and tissue cultures of the variety CH532226, and to methods for producing a corn plant produced by crossing a corn plant of variety CH532226 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH532226.Type: ApplicationFiled: May 31, 2018Publication date: December 5, 2019Inventors: Christian J. Buffard, Jeffrey M. Sernett, Gary R. Stangland
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Publication number: 20190364837Abstract: According to the invention, there is provided seed and plants of the hybrid corn variety designated CH532426. The invention thus relates to the plants, seeds and tissue cultures of the variety CH532426, and to methods for producing a corn plant produced by crossing a corn plant of variety CH532426 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH532426.Type: ApplicationFiled: May 31, 2018Publication date: December 5, 2019Inventors: Christian J. Buffard, Jeffrey M. Sernett, Gary R. Stangland
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Publication number: 20190364838Abstract: According to the invention, there is provided seed and plants of the hybrid corn variety designated CH532633. The invention thus relates to the plants, seeds and tissue cultures of the variety CH532633, and to methods for producing a corn plant produced by crossing a corn plant of variety CH532633 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH532633.Type: ApplicationFiled: May 31, 2018Publication date: December 5, 2019Inventors: Christian J. Buffard, Jeffrey M. Sernett, Gary R. Stangland
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Publication number: 20190364839Abstract: According to the invention, there is provided seed and plants of the hybrid corn variety designated CH545507. The invention thus relates to the plants, seeds and tissue cultures of the variety CH545507, and to methods for producing a corn plant produced by crossing a corn plant of variety CH545507 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH545507.Type: ApplicationFiled: May 31, 2018Publication date: December 5, 2019Inventors: Fufa H. Birru, Christian J. Buffard, Jeffrey M. Sernett
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Publication number: 20190364840Abstract: An automated litter device having: a) a chamber configured to hold litter to allow an animal to enter and excrete waste; b) a waste drawer in communication with the chamber and configured to receive the waste; c) one or more sensors configured to detect one or more conditions of the device and transmit one or more signals related to the one or more conditions; d) a controller in communication with the one or more sensors which is adapted to receive the one or more signals, wherein the controller is configured to determine one or more positions of the chamber based on the one or more signals received from the one or more sensors and interpret the one or more signals as one or more status signals; e) a communication module in communication with the controller and adapted to communicate with a user interface via a network to transmit the one or more status signals to the user interface, receive one or more instruction signals via the user interface, or both; wherein the user interface is adapted to transmit theType: ApplicationFiled: May 31, 2019Publication date: December 5, 2019Inventors: Brad Baxter, Jacob Zuppke
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Publication number: 20190364841Abstract: A machine or apparatus to capture dog urine and solid waste for generally indoor use by a dog owner that automatically or manually advances fresh pads on a predetermined programming of the machine by the control module or by using markings or shadings on a roll of pet waste material.Type: ApplicationFiled: July 16, 2019Publication date: December 5, 2019Inventors: Alan J. Cook, Thomas E. Devlin, Kris W. Grube
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Publication number: 20190364842Abstract: An automatic locking joint for use with a reconfigurable device to permit the device to be selectively reconfigurable between various configurations.Type: ApplicationFiled: August 19, 2019Publication date: December 5, 2019Applicant: Nelson & Nielsen LLCInventors: Shane Nelson, Gary Nielsen
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Publication number: 20190364843Abstract: The present invention relates to pet bed cover apparatuses and systems. Specifically, the pet bed covers comprise a medical-grade water resistant or water-proof material that is sized and fits over a pet bed to provide a cover for the pet bed. Alternatively, the present invention comprises wipes made from medical-grade material having essential oils embedded therein. Methods of making and using the same are further provided.Type: ApplicationFiled: March 18, 2019Publication date: December 5, 2019Inventor: Karen Murphy
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Publication number: 20190364844Abstract: An animal protection apparatus includes a body with a collar to secure around an animal's body and neck; a padded base attached to the body; and a net positioned under the padded base; the net and padded base can fold around the animal's body and can be used to lift and carry the animal.Type: ApplicationFiled: June 1, 2019Publication date: December 5, 2019Inventor: Darren Mark Teren
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Publication number: 20190364845Abstract: A feeding device for working animals comprises a conveyor with a plurality of receiving regions for a feed, where the receiving regions are arranged along the conveyor chain and are accessible from above for the working animals, a feed supply device for supplying feed to the receiving regions, and a guide device for guiding the conveyor along a predetermined path. The guide device guides the conveyor in a first path section of the predetermined path parallel and in a horizontal direction adjacent to a second path section of the predetermined path. The conveyor is guided in the first path section in a first conveying direction which is opposed to a second conveying direction in which the conveyor is guided in the second path section.Type: ApplicationFiled: November 10, 2017Publication date: December 5, 2019Applicant: BIG DUTCHMAN INTERNATIONAL GMBHInventor: Eike-Steffen Wienken
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Publication number: 20190364846Abstract: A feeder for pigs includes a hopper and a trough for receiving the feed where an elongate opening is defined by an elongate shelf to control the amount of feed discharged from the hopper to the trough. An adjustment linkage for lifting the shelf against the weight of feed in the hopper includes a first lift screw and a second lift screw each for applying a lifting force to the elongate adjustment member located at spaced positions from the end walls of the hopper. Each of the screws includes a gear box with a shaft connected between the two gear boxes to communicate drive therebetween for simultaneous operation of the lift screws by a hand crank connected to one at the top of the feed in the hopper.Type: ApplicationFiled: May 29, 2019Publication date: December 5, 2019Inventors: Jonathan Kleinsasser, Tom McAdams
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Publication number: 20190364847Abstract: An animal back support apparatus includes a main back support, a chest harness and an optional lumbar support component. The main back support features relatively rigid stays placed over the spine and one on each side of the spine and foam inlays to conform to the pets back between the pets back and the rigid stays. The animal back support apparatus also includes a first side panel on one side of the main back support and a second side panel on an opposite side of the main back support where the first and second side panels extend towards the abdomen of the animal and interact with each other to encircle the torso of the animal. The chest harness attaches to the main support layer.Type: ApplicationFiled: May 30, 2018Publication date: December 5, 2019Inventor: Renee Mills
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Publication number: 20190364848Abstract: A horse boot comprises a shell with front and lateral sidewalls. The sole has a longitudinal slot and an open rear end for access to the slot. The slot may be open or closed. A heel support includes a bottom plate for slidable engagement with the slot at a desired length position. Straps wrap around the hoof and connect the heel support to the shell of the boot. The heel support comprises a back plate and a heel cradle slidably coupled to the back plate for vertical adjustment. Straps extend forward attached to the front portion of the shell. In another embodiment a heel cradle structure includes bands fastened to the rear of the shell, thereby defining bulb retaining openings. A strap wrapped around the hoof is attached to the bands. The boot is fitted adjusting length and height to optimize the way it is fastened to the hoof.Type: ApplicationFiled: May 29, 2019Publication date: December 5, 2019Applicant: EASYCARE, INC.Inventor: GARRETT N. FORD
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Publication number: 20190364849Abstract: A dog collar-leash combination including a collar (1) and a leash (2) in a housing (20), which leash is made available by means of a rolling and unrolling mechanism (21). The leash (2) in the housing (20) can be unwound against a spring force. An outer end of the leash (2) has a grip (22). The collar (1) has first and second free ends (11, 12) and the housing (20) for the leash (2) is provided on the first end (11) and a loop (13), through which the leash (2) is fed, is provided on the second end (12).Type: ApplicationFiled: January 25, 2018Publication date: December 5, 2019Inventor: Walburga FALKENBERG
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Publication number: 20190364850Abstract: A guide dog apparatus comprises a form fitting guide dog harness, an extensible and rotatable human guiding handle, and a single point attachment mechanism connecting the dog harness and human guiding handle. The harness includes a dorsal panel and a ventral panel. A user handle is connected to an attachment member that is mounted to the dorsal panel of the harness and which includes a clamping gudgeon that retains a pintle attached to the handle in a desired orientation. The apparatus positively couples linear guiding forces in the ventral, dorsal, cranial, and caudal directions. The guiding handle attachment positively couples rotational guiding forces about the vertical dorsoventral axis and the horizontal anteroposterior axis. Freedom of rotation is provided about the lateral horizontal left-right axis. The user is able to laterally adjust the distance between grip and the harness.Type: ApplicationFiled: June 1, 2018Publication date: December 5, 2019Applicant: Ruff Wear, Inc.Inventors: Patrick Kruse, Colin Tisdale, Timothy Gorbold
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Publication number: 20190364851Abstract: A dog harness, has a main body, formed of a material having a front section, a back section, a first leg opening, and a second leg opening. The top portion of the main body has a center opening, a first extending section overlapping with a second extending section and separable from said second extending section, and a connection section, which connects between the first extending section and the second extending section and holding the first extending section relative to the second extending section and also allowing disconnection between the first extending section and the second extending section. A pocket extends above a surface of the first extending section, and having an interior cavity, and the pocket having a slot at a top section thereof, the slot being effective to allow dispensing dog waste bags through a surface of the pocket without opening the flap closing the pocket.Type: ApplicationFiled: May 31, 2018Publication date: December 5, 2019Inventor: Michelle Deluya
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Publication number: 20190364852Abstract: A bird feeder comprising a seed tube having an open top end and an open lower end, a cover arranged to sit on top of the open top end of the seed tube, the cover being removably attached to the seed tube, a seed tube base removably attached to the open lower end, the seed tube base having a bottom wall and a circular side wall with a plurality of feed openings in the circular wall, a shroud extending around the seed tube base, the shroud having shroud feed openings therein which are normally aligned with the feed openings in the circular side wall of the seed tube base, the shroud moving to a position wherein the shroud feed openings and the feed openings in the circular side wall of the seed tube base are out of alignment when a weight above a predetermined amount is present on the shroud.Type: ApplicationFiled: June 1, 2018Publication date: December 5, 2019Inventor: Paul L. COTE
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Publication number: 20190364853Abstract: A method and system for protecting apiaries by means of thermal and moisture membranes. The invention being comprised of one-piece, rigid, yet foldable, modular units. Said thermal and moisture membranes being configured in such a manner as to keep a hive dry, insulate a hive in cold climates and reflect radiant heat back into a hive. Conversely, said membrane also moderating heat in the summer by reflecting thermal radiation. The membranes also minimizing the growth of pathogens and bacteria within a hive. An object of the invention being to promote the health of anthophila broods therein.Type: ApplicationFiled: June 4, 2018Publication date: December 5, 2019Inventors: Steven Allen Voisin, William Robert Thomas, Gregory Michael Rohrbach
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Publication number: 20190364854Abstract: A coral frag plug holder and system includes a main body and an interchangeable attachment device. The main body includes a first main end and a second main end. The first main end includes an opening configured to receive a coral frag plug. The second main end includes a main connector. The interchangeable attachment device includes a first attachment end and a second attachment end. The first attachment end includes an attachment connector configured to connect to the main connector of the main body. The second attachment end includes an attachment means configured to attach to a surface of an aquarium. Wherein, when the attachment means is attached to the surface of the aquarium, the attachment means positions the main body on the surface of the aquarium, whereby, coral frag plug is positioned on the surface of the aquarium.Type: ApplicationFiled: May 30, 2018Publication date: December 5, 2019Inventor: David WOLDMAN
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Publication number: 20190364855Abstract: Embodiments of the invention provide a tank assembly with a main housing enclosing an inner volume, and an outlet section positioned extending from one end of the main housing that includes a front cavity with an outlet volume and an adjacent outlet channel. Some embodiments include at least one removable filter configured to be inserted at least partially into main housing forming at least a filtered volume and a fluidly coupled main volume. Some embodiments include a removable tank baffle including at least one central channel and a plurality of baffle apertures. In some embodiments, the central channel is configured to be fluidly coupled to the outlet channel when the removable tank baffle is positioned in the main housing. Further, the plurality of baffle apertures are configured to be fluidly coupled to the outlet volume when the removable tank baffle is positioned in the main housing.Type: ApplicationFiled: May 30, 2018Publication date: December 5, 2019Inventors: Jean Daher, Nobutoshi Sato, Christopher Collins, William Lane Peacock, Eric Moore, John Peter Miersma
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Publication number: 20190364856Abstract: An aquaculture system including an aquaculture tank for holding aquaculture water for conducting biofloc aquaculture therein, and an immobilizing material in the aquaculture tank. The immobilizing material includes a carrier that carries nitrifying bacteria.Type: ApplicationFiled: August 16, 2019Publication date: December 5, 2019Applicant: Nippon Suisan Kaisha, Ltd.Inventor: Hiroshi MINAMI
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Publication number: 20190364857Abstract: An aquaculture system including an aquaculture tank for holding aquaculture water for culturing an aquatic organism, a thermal insulation house that covers the aquaculture tank, an insulation positioned on at least part of a region surrounding the aquaculture tank, and a temperature adjuster that adjusts a temperature inside the thermal insulation house and/or a temperature of the aquaculture water in the aquaculture tank.Type: ApplicationFiled: August 16, 2019Publication date: December 5, 2019Applicant: Nippon Suisan Kaisha, Ltd.Inventors: Hiroshi Minami, Mitsuho Maeda, Eisuke Yasue, Kosuke Matsuoka
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Publication number: 20190364858Abstract: This disclosure describes exemplary embodiments of a method of creating a YY animal broodstock, preferably in a single generation, wherein the broodstock includes only sperm-producing YY males and egg-producing YY males, the method comprising the steps of: (a) creating YY males via androgenesis; (b) exposing selected ones of the YY males created in step (a) to a feminizing hormone; and (c) identifying sperm-producing YY males and egg-producing YY males from among the YY males created in steps (a) and (b). In other embodiments, the method further comprises: (d) repeating steps (a) through (c) N times in order to produce N unrelated families of sperm-producing YY males and egg-producing YY males; and (e) cross-breeding various ones of the unrelated families produced in step (d) in order to produce a genetically-diverse YY progeny. In some embodiments, N may be about 60.Type: ApplicationFiled: August 8, 2019Publication date: December 5, 2019Inventor: Daniel J. Schill
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Publication number: 20190364859Abstract: The present invention provides a prophylactic or therapeutic agent for a kidney disease, comprising Apoptosis Inhibitor of Macrophage (AIM) or a partial peptide thereof, or a nucleic acid comprising a base sequence encoding the same, or a screening method for a prophylactic or therapeutic agent for a kidney disease, comprising using an animal obtained by subjecting a non-human mammal deficient in AIM expression to unilateral ureteral obstruction or transient kidney ischemia/reperfusion and the like.Type: ApplicationFiled: July 11, 2019Publication date: December 5, 2019Inventor: Toru MIYAZAKI
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Publication number: 20190364860Abstract: The present disclosure relates to the genetically modified non-human animals that express a human or chimeric (e.g., humanized) Lymphocyte Activation Gene 3 (LAG-3), and methods of use thereof.Type: ApplicationFiled: May 10, 2019Publication date: December 5, 2019Inventors: Yuelei Shen, Yanan Guo, Chaoshe Guo, Yang Bai, Jiawei Yao, Lei Zhao, Rui Huang
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Publication number: 20190364861Abstract: The present disclosure relates to genetically modified non-human animals that express a human or chimeric (e.g., humanized) glucocorticoid-induced TNFR-related protein (GITR), and methods of use thereof.Type: ApplicationFiled: June 7, 2019Publication date: December 5, 2019Inventors: Yuelei Shen, Yanan Guo, Yang Bai, Jiawei Yao, Rui Huang, Lei Zhao, Meiling Zhang
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Publication number: 20190364862Abstract: CRISPR/Cas9-mediated genome editing holds clinical potential for treating genetic diseases, such as Duchenne muscular dystrophy (DMD), which is caused by mutations in the dystrophin gene. In vivo AAV-mediated delivery of gene-editing components machinery has been shown to successfully remove mutant sequence to generate an exon skipping in the cardiac and skeletal muscle cells of postnatal mdx mice, a model of DMD. Using different modes of AAV9 delivery, the restoration of dystrophin protein expression in cardiac and skeletal muscle of mdx mice was achieved. Here, a humanized mouse model for DMD is created to help test the efficacy of genome editing to cure DMD. Additionally, to facilitate the analysis of exon skipping strategies in vivo in a non-invasive way, a reporter luciferase knock-in version of the mouse model was prepared. These humanized mouse models provide the ability to study correcting of mutations responsible for DMD in vivo.Type: ApplicationFiled: December 8, 2017Publication date: December 5, 2019Applicant: The Board of Regents of the University of Texas SystemInventors: Leonela AMOASII, Chengzu LONG, Rhonda BASSEL-DUBY, Eric OLSON
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Publication number: 20190364863Abstract: An apparatus and methods relating to Diamondback Rattler tackle, a new type of lure that includes an audible generator (such as a rattle) attached to a bent blade. The audible generator has some freedom of movement relative to the blade, allowing various noise profiles to be produced depending upon the type of audible generator chosen and the degree of bend in the blade. The blade may also have various holes to secure it to a wire and to change its hydrodynamic profile.Type: ApplicationFiled: August 20, 2019Publication date: December 5, 2019Inventor: Robert Coxey
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Publication number: 20190364864Abstract: A fishing attractor that communicates through a fish's electroreceptor lateral line that is used in water to attract nearby fish by appealing to the fish's six senses. The fishing attractor includes a wire shaft, a copper bead, a propeller having one or more blades and a central portion with a first magnet inside and a second magnet arranged in reverse polarity to the first magnet. Embodiments include a fishing attractor that when moved, the blades of the propeller begin to rotate and the copper bead and propeller move in a linear motion as well causing the first magnet to rotate and move up and down along the wire shaft, producing an electric potential pulse from the electromagnetic field created by the first and second magnets in opposing relation and from exciting electrons in the wire.Type: ApplicationFiled: June 4, 2018Publication date: December 5, 2019Inventor: Kenneth R. JACOBSON
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Publication number: 20190364865Abstract: Provided is a bait casting reel for preventing friction or break of a spool plate and a braking magnet due to contact by deformation of a rotary shaft of a spool or a friction washer, etc., by employing a variable spool plate coupled to be able to move left and right in the longitudinal direction of a spool shaft so that a user can easily and freely adjust a braking force after setting a maximum braking force of a braking magnet without replacing or changing parts, and by enabling a user to perform zero adjustment such that the spool plate and the braking magnet is minimally spaced to set a maximum braking force of the braking magnet by moving the spool plate and the braking magnet in contact with each other when the spool plate is moved the outermost side.Type: ApplicationFiled: May 29, 2019Publication date: December 5, 2019Inventor: Kang Ho Hyun