Abstract: The present invention is related to novel oral compositions comprising an irreversible gastric H+/K+-ATPase proton pump inhibitor (PPI) as a gastric acid secretion inhibitor and one or more aliphatic carboxylic acid derivative molecules which activate parietal cells, wherein the derivatives possess delayed or sustained enhancement effect on the PPI activity compared to the non-derivatized acid molecules. The present invention further relates to a method of using such compositions to reduce gastric acid secretion in a mammal.
Type:
Grant
Filed:
July 19, 2007
Date of Patent:
January 12, 2016
Assignee:
Vecta, Ltd.
Inventors:
Michael Marash, Aleksey Kostadinov, Tal Atarot
Abstract: Waterborne aqueous-alcohol soluble protein compositions, methods of making the compositions, and applications thereof are disclosed. The dispersion compositions include protein, water, acid, and optionally an ester of a carboxylic acid. The methods of making the compositions including combining the protein, water, acid and optionally ester to form a dispersion without the benefit of alcohol. Applications include industrial and food applications, such as binders and coatings, for example paint binders or coatings for paper products and pharmaceuticals.
Abstract: An indicator is useful for detecting pressure points on a denture. The indicator is made of a composition that easily adheres to oral mucosa, has a proper viscosity in an oral cavity environment, can be properly spread between an oral mucosa surface and a denture base, and easily specifies an affected part. The composition includes a fatty acid ester having a melting point of 30 to 50° C., a water-soluble high polymer, and a metal oxide. Preferably, the fatty acid is 40 to 95% by weight of the composition, the water-soluble high polymer is 1 to 59% by weight of the composition, and the metal oxide is 0.1 to 50% by weight of the composition.
Abstract: The invention is directed to thermoplastics derived from feathers. The thermoplastics are prepared by blending whole feathers or portions thereof with a plasticizer in an amount ranging from about 20 wt to about 40 wt % and a reducing agent in an amount ranging from about 1 wt % to about 5 wt % to form a mixture; and either extruding the mixture to form an article, or pressing the mixture into a film at an elevated temperature.
Type:
Application
Filed:
August 27, 2013
Publication date:
March 6, 2014
Applicant:
THE GOVERNORS OF THE UNIVERSITY OF ALBERTA
Inventors:
Jianping WU, Aman ULLAH, David BRESSLER
Abstract: The present teachings provide new compositions comprising polycations and polycations, and the preparation and use of these new compositions. In one aspect, the new compositions are complex coacervates. The compositions described herein can have several desired properties, including, low interfacial tension in water, adjustable cohesive strength, antimicrobial activity, suitability for dissolution at or near physiological pH, biocompatiblility, and/or biodegradability. The compositions can have the ability of promoting cell attachment, cell adhesion, cell migration, cell differentiation, and/or morphogenesis. Thus, in various embodiments, the complex coacervates can be used in water-based applications, for example, in the body.
Abstract: The present invention is a biodegradable, reversibly-swellable, polyvalent cation-binding, protein hydrogel which comprises an acylated protein matrix in which the acylated protein matrix is crosslinked with a bifunctional crosslinking reagent, and treated with a polar organic solvent, and a method of making the same.