Abstract: To expose a desired feature, focused ion beam milling of thin slices from a cross section alternate with forming a scanning electron image of each newly exposed cross section. Milling is stopped when automatic analysis of an electron beam image of the newly exposed cross section shows that a predetermined criterion is met.
Type:
Grant
Filed:
January 29, 2019
Date of Patent:
January 7, 2020
Assignee:
FEI Company
Inventors:
Scott Edward Fuller, Jason Donald, Termsupt Seemuntchaiboworn
Abstract: A fiber-reinforced hydrogel composite is provided. The composite includes a hydrogel and a fibrous component containing a plurality of fibers. Length of each of the plurality of fibers is less than about 1,000 ?m. A method of preparing a fiber-reinforced hydrogel composite is also provided. The method includes coating a hydrogel precursor solution on a substrate to form a hydrogel precursor film, depositing the plurality of fibers onto the hydrogel precursor film, and allowing the hydrogel precursor film to form a hydrogel film, (ii) thereby forming the fiber-reinforced hydrogel composite. A scaffold containing the fiber-reinforced composite, and a tissue repair method (iii) using the fiber-reinforced composite are also provided.
Abstract: The present invention concerns stable aqueous protein dispersions comprising in an aqueous phase at least one self-assembling protein in dispersed form and also at least one specific dispersant for the self-assembling protein; processes for producing such stable aqueous dispersions; processes for electrospinning self-assembling proteins using such stable aqueous dispersions; processes for producing fibrous sheet bodies or fibers from such aqueous dispersions; the use of such aqueous dispersions for coating surfaces; the use of the materials produced by electrospinning in the manufacture of medical devices, hygiene articles and textiles; and also fibrous or fibrous sheet bodies produced by an electrospinning process of the present invention.
Type:
Application
Filed:
February 3, 2014
Publication date:
July 10, 2014
Applicants:
Freudenberg Forschungsdienste KG, BASF SE
Inventors:
Evgueni Klimov, Burghard Liebmann, Thomas Subkowski, Martin Möller, Doris Klee, Artem Davidenko, Wiebke Voigt, Gunter Scharfenberger
Abstract: Biocompatible phase invertible proteinaceous compositions and methods for making and using the same are provided. Phase invertible compositions in accordance with the invention are prepared by combining a liquid proteinaceous substrate and a liquid crosslinking composition, where the liquid crosslinking composition includes a macromolecular crosslinking agent. Also provided are kits for use in preparing the subject compositions. The subject compositions, kits and systems find use in a variety of different applications.
Type:
Application
Filed:
May 15, 2012
Publication date:
September 6, 2012
Applicant:
Tenaxis Medical, Inc.
Inventors:
Ronald Dieck, Ian J. Handley, Neil Winterbottom, Joanna Wong
Abstract: The present invention concerns stable aqueous protein dispersions comprising in an aqueous phase at least one self-assembling protein in dispersed form and also at least one specific dispersant for the self-assembling protein; processes for producing such stable aqueous dispersions; processes for electrospinning self-assembling proteins using such stable aqueous dispersions; processes for producing fibrous sheet bodies or fibers from such aqueous dispersions; the use of such aqueous dispersions for coating surfaces; the use of the materials produced by electrospinning in the manufacture of medical devices, hygiene articles and textiles; and also fibrous or fibrous sheet bodies produced by an electrospinning process of the present invention.
Type:
Application
Filed:
August 25, 2011
Publication date:
April 12, 2012
Applicants:
Freudenberg Forschungsdienste KG, BASF SE
Inventors:
Evgueni Klimov, Burghard Liebmann, Thomas Subkowski, Martin Möller, Doris Klee, Artem Davidenko, Wiebke Voigt, Gunter Scharfenberger
Abstract: The present invention relates to a bioadhesive derived from mussel. In particular, it relates to a novel Mytilus galloprovincialis foot protein type 5 (MGFP-5) and a recombinant protein that is a hybrid of MGFP-5 and foot protein type 1 (FP-1), where an adhesive protein with adhesive activity can be economically mass-produced to be used in place of chemical adhesives through the present invention.