Abstract: A medication dispensing system configured to prepare a plurality of syringes for medication delivery, the system comprising a turntable carrying a plurality of medication vials, each medication vial being engaged to a smart vial adapter, a translation stage carrying a plurality of syringes, a base having a plurality of arms configured to interact with the plurality of syringes, and a processor that is programmed to rotate the turntable, axially move the translation stage and operate the plurality of arms such that a selected syringe of the plurality of syringes engages a selected medication vial of the plurality of medication vials to draw medicament.

Abstract: Introduced here are universal modular attachments that can be attached to medication containers. Because a single modular attachment is typically attachable to medication containers of different sizes, the modular attachment can be referred to as a “universal modular attachment.” For example, some universal modular attachments are attachable to any cylindrical eye drop container having a diameter ranging from 20 millimeters (mm) to 27 mm. A connector ring that substantially matches the diameter of the medication container secures the universal modular attachment to the medication container. The connector ring may be fixedly affixed to the medication container, while the universal modular attachment may be detachably connectable to the connector ring. Each universal modular attachment also includes sensor(s) that are configured to detect administrations of medication.

Abstract: A combination of an inhaler and a refill pack. The inhaler comprises a reservoir for an inhalable composition, a heating element and/or vibrating transducer to selectively volatilise at least some components of the composition and at least one inhaler capacitor arranged to supply electrical power to the heater and/or vibrating transducer when a user inhales from the inhaler. The refill pack comprises a refill reservoir of inhalable composition and a battery coupled to a refill capacitor, and is arranged to engage with the inhaler and to simultaneously refill the reservoir and recharge the inhaler capacitor from the refill capacitor. The invention also extends to the inhaler and refill pack separately and to a method of refilling and recharging the inhaler.

Abstract: An electronic nicotine delivery device, with a first end, a second end and a body, the body comprising of a transparent cylindrical outer casing, a battery, a heating element, and a liquid, the first end comprising of a mouthpiece and a first tamper seal, the mouthpiece having an opening for receiving vapor, the first tamper seal having a hole which is flush with the opening, the second end distal from the first end, wherein the second end comprises of a stop and a second tamper seal, the stop further comprising of one or more air holes, the second tamper seal not covering the one or more air holes.

Abstract: The present invention is a collapsible/expandable and disposable spacer for use with a metered dose inhaler (‘MDI’).

Abstract: A device atomizes or vaporizes a liquid for inhalation. A housing has a proximal exit orifice that communicates with an intake orifice. A housing encompasses a reservoir containing a liquid. A wick has a first end in contact with the liquid and a second end that is exposed at an opening in the reservoir. A heater is disposed within housing in an air passage that communicates between the intake orifice and the proximal exit orifice. An actuator responds to a user of the device by placing the heater and the second end of the wick into proximity with the heater to vaporize the liquid.

Abstract: On-demand, hand-held vaporizer that operates primarily by convection. The vaporizer is configured to permit very rapid heating of air drawn through an oven chamber to a predetermined or selectable vaporizing temperature to vaporize a material that is held in the oven chamber. The vaporizer provides efficient transfer of air being heated as well as rapid delivery of vaporizable material to a user.

Abstract: The invention relates to an inhalation device for powdered drugs to be received by a patient by an inhalation-caused air stream, comprising at least one powder reservoir, metering means for repeatedly metering a powder dose from the reservoir, a transportation mechanism for moving said metering means from a filling position for receiving a powder dose into an emptying position for releasing said powder dose into a powder channel, at least one activating device for manual operation by the patient, said activating device being operatively connected to said transportation mechanism such that upon operation a single powder dose is being metered, said activating device comprising a dosage key (5) acting on said transportation mechanism when pressed by the patient. The inhalation device further comprises an advancing mechanism for advancing a counter means each time the inhalation device has been activated by the patient so that a powder dose has been released into the powder channel.

Abstract: An atomizing element for an electronic cigarette is provide, which includes: a porous body comprising an atomizing surface and a liquid absorbing surface; and a porous heating film formed on the atomizing surface. An electronic cigarette and an atomizing assembly including the same are also provided.

Abstract: Surface treatment process of a metering valve, said metering valve comprising a valve body and a valve sliding in said valve body, said process comprising a first step of forming a thin film of silicone by chemical grafting on at least one support surface of said valve body and/or said valve, and a second step of applying free silicone on said thin film of grafted silicone, such that said treated support surface simultaneously comprises grafted silicone and free silicone, siloxane chains of the grafted silicone and free silicone associating chemically together to reinforce the holding of the free silicone on said thin film of grafted silicone.

Abstract: A cosmetic container having an identification means, wherein a user can intuitively identify contents through the identification means by providing an identification means for identifying contents at the upper portion of the container body, such that it is possible to easily classify cosmetic products according to contents when storing the cosmetics, thereby providing user convenience.

Abstract: A dose counter for counting doses of medicament dispensed by or remaining in a metered-dose inhaler. The dose counter includes a rotatably mounted first gear wheel having ratchet teeth and a display coupled to the first gear wheel, the display having a visible array of dose counting indicia indexable in response to rotary motion of the first gear wheel. The dose counter further includes an actuator mechanism having a first ratchet drive pawl for engaging the ratchet teeth of the first gear wheel in response to the dispensation of a medicament dose, and a second ratchet drive pawl for engaging the ratchet teeth of a gear wheel coupled to the display. In use, a first ratchet tooth of the first gear wheel is rotatably driven by the first pawl and then a second ratchet tooth of the gear wheel coupled to the display is rotatably driven by the second pawl.

Abstract: The present invention provides an electronic cigarette. The electronic cigarette includes a sensor, an atomizing assembly and a liquid storage unit, which are disposed in a housing. The atomizing assembly is provided with a first airflow passage. A second airflow passage is provided in the housing, and the sensor is disposed in the second airflow passage. The housing is defined with a first air inlet and a second air inlet. The first air inlet is in fluid communication with the first airflow passage. The second air inlet is in fluid communication with the second airflow passage. The first airflow passage and the second airflow passage are isolated from each other by a partition member.

Abstract: The invention relates to an inhalation device for powdered drugs to be received by a patient by an inhalation-caused air stream, comprising at least one powder reservoir, metering means for repeatedly metering a powder dose from the reservoir, a transportation mechanism for moving said metering means from a filling position for receiving a powder dose into an emptying position for releasing said powder dose into a powder channel, at least one activating device for manual operation by the patient, said activating device being operatively connected to said transportation mechanism such that upon operation a single powder dose is being metered, said activating device comprising a dosage key (5) acting on said transportation mechanism when pressed by the patient. The inhalation device further comprises an advancing mechanism for advancing a counter means each time the inhalation device has been activated by the patient so that a powder dose has been released into the powder channel.

Abstract: This present disclosure describes a computer-implemented method for updating a plurality of parameters on a medical inhaler sensor via a wireless connection by a client device. The client device stores the plurality of parameters for the medical inhaler sensor on the client device. The client device updates one or more parameters of the plurality of parameters on the client device. The client device receives a plurality of periodic chirps from the medical inhaler sensor, and can establish the wireless connection with the medical inhaler sensor in response to having received a chirp. Through the wireless connection, the client device transmits the updated one or more parameters of the plurality of parameters to the medical inhaler sensor.

Abstract: An electronic vapor provision device comprising a power cell and a vaporizer, wherein the vaporizer comprises a heating element and a heating element support, and wherein the heating element support is a flat planar substrate.

Abstract: The invention relates to a device for administration of a pharmaceutical with a) a reservoir (1) for storage of the pharmaceutical, wherein the reservoir (1) has a dispensing opening (2), b) a trigger means (3) for triggering an administration of a pharmaceutical, in which the pharmaceutical is dispensed through the dispensing opening (2), c) an information storage medium (4) for storage of administration data, wherein d) a converter means (5) for converting analog administration data into digital administration data, e) a wireless information transmitter means (6) for transmitting the administration data to an external display and/or storage medium, and e) a power generator means (7) for providing electrical power for the converter means (5), information storage medium (4) and/or the information transmitter means, are provided.

Abstract: An electronic cigarette includes: a power supply portion which supplies power to the electronic cigarette; an elevating portion being controllable up and down by the supplied power; a smoke generating portion coupled to the elevating portion to be movable up and down; and a connector portion which connects between the smoke generating portion and the elevating portion.

Abstract: A nasal delivery device for and method of delivering substance to a nasal airway of a subject, the delivery device comprising: a nosepiece (117) for fitting to a nasal cavity of a subject; a mouthpiece (119) into which the subject in use exhales; a delivery unit, which comprises an actuation part which is manually displaceable to actuate the delivery unit to deliver substance from the nosepiece; and a valve assembly (127) which is fluidly connected to the nosepiece and the mouthpiece, wherein the valve assembly comprises a body element (128) and a valve element (131) which is movably disposed to the body element between closed and open configurations by manual displacement of the actuation part of the delivery unit to provide for an air flow through the nosepiece simultaneously with delivery of substance.

Abstract: A spacer may improve the effectiveness of medication delivery by an inhaler. The spacer may be configured to store the inhaler to improve compactness and/or portability of the spacer and inhaler. The inhaler may be coupled to a retaining device, inhaler container, and/or the like that restricts movement of the inhaler to predetermined positions and/or orientations. A user may be able to transition the inhaler between a stored position and an active position by moving the inhaler translationally and/or rotationally. The inhaler may be able to remain coupled to the retaining device and/or inhaler container, and the retaining device and/or inhaler container may be able to remain coupled to the spacer during transition from the stored position to the active position. The spacer may be sized to fit in a pants pocket in an embodiment.

Abstract: An electronic cigarette device having a disposable tank are described. The disposable tank may have a sealed liquid chamber, an atomizer element and a tank well.

Abstract: Fluid delivery device for discharging a fluid, having: a housing; piston pump; biasing mechanism; and trigger mechanism. The housing has a basal end and a discharge end with outlet for discharging the fluid. The piston pump has a casing defining a pump chamber for storage of fluid, a piston slidably movable relative to the pump chamber, a piston plunger, and a delivery channel. The trigger mechanism is movable from a cocked configuration wherein the trigger mechanism prevents transfer of a biasing force of the biasing mechanism to the casing to a triggered configuration with the trigger mechanism enabling transfer of the biasing force to the casing to cause movement of the casing towards the housing outlet to discharge fluid from the pump chamber, along the delivery channel and out of the outlet of the housing. The biasing mechanism has one or more flexible catch members and a manually operable trigger.

Abstract: Cartridges for use with a vaporizer body are provided. In some implementations, a cartridge having a top end and a bottom end comprises a mouthpiece proximate to the top end, a transparent storage compartment configured to store vaporizable material, and a heater assembly attached to the transparent storage compartment at the bottom end. The heater assembly comprises a heating element, a pair of electrical contacts, a wick, and a heater chamber formed at least in part from two metal walls configured to provide a heat shield between the heating element and the storage compartment, coupled to the pair of electrical contacts. The pair of electrical contacts are disposed at the bottom end and are configured to complete an electrical circuit with the vaporizer body when the cartridge is inserted into the vaporizer body.

Abstract: The present invention relates to improvements made in the blister advancement mechanism of dry powder inhaler devices. A dry powder inhaler device mechanism comprising an actuator plate and a transmission wheel is provided.

Abstract: Apparatuses including vaporizer device bodies and cartridges are provided. In some implementations, an apparatus includes a cartridge and a body. The cartridge comprises a storage compartment configured to hold a vaporizable material, a heater chamber including a heating element configured to heat the vaporizable material to generate an aerosol, and an outlet for the aerosol. The body comprises a receptacle configured to insertably receive and couple to the cartridge, and first and second electrical contacts configured to complete an electrical circuit with the heating element. The cartridge and the body are configured to define an airflow path comprising an air inlet passage having a first side formed by an exterior surface of the cartridge and a second side formed by an internal surface of the receptacle. The air inlet passage is configured to deliver air towards the heater chamber, which is in fluid communication with the outlet.

Abstract: A pen-type injector is improved so that a user may select a delivery dose of a medicinal product from a multidose cartridge. The injector includes a housing, a cartridge containing the medicinal product retained within the housing, a piston rod, a dose selecting member to select the dose of medicinal product to be expelled, and a drive member to expel the selected dose of the medicinal product. The housing is formed unitary so that the dose selecting member and the drive member are moveably retained within the housing. The injector may include a ratchet associated with an insert to ensure the piston rod only rotates in a single direction through the insert, a button located on the drive member, and a clutch which upon depression of the button prevents rotation between the dose selecting member and the drive member.

Abstract: A nasal spray device for the delivery of a pharmaceutical formulation to the nasal cavity in metered doses. The device includes: a pressurised aerosol canister including a vial containing a pharmaceutical formulation including an active ingredient, a propellant and, optionally, a co-solvent, the aerosol canister further including a metering valve having a valve stem; and an actuator for the aerosol canister, the actuator including a stem block having a receptacle into which the valve stem of metering valve of the aerosol canister is received and axially located and being displaceable relative to the vial of the aerosol canister to actuate the metering valve of the aerosol canister, a sump extending below the receptacle, the stem block further defining a discharge orifice for the pharmaceutical formulation and a transfer channel through which a dispensed dose of the pharmaceutical formulation is able to pass from the sump to the discharge orifice.

Abstract: An incremental dose counter for a metered dose inhaler having a body arranged to retain a canister for movement of the canister relative thereto, the incremental dose counter having a main body, an actuator arranged to be driven and to drive an incremental output member in a count direction in response to canister motion, the actuator being configured to restrict motion of the output member in a direction opposite to the count direction.

Abstract: The invention relates to pharmaceutical powder compositions administered by means of inhalers. More particularly, it relates to pharmaceutical powder compositions having the content uniformity and the desired stability used in inhaler devices.

Abstract: The present disclosure relates to a dose indicator for a pressure-actuated metered dose inhaler (pMDI) device. In an embodiment, the dose indicator comprises a chassis element having a viewing portion, a display element located within the chassis element, a resilient deformable element, and an indexing element having an axis, translation of the indexing element along its axis from a first position to a second position causing deformation of the resilient deformable element in the same direction as translation of the indexing element resulting in generally greater displacement of portions of the resilient deformable element nearer to the axis relative to portions thereof further from the axis, the displacement of the portions of the resilient deformable element in the same direction as translation of the indexing element inducing indexing of the display element from a current position to a subsequent position relative to the viewing portion of the chassis element.

Abstract: A dilution spacer for a metered-dose inhaler comprises an enclosure defining a dilution chamber. An ambient air inlet and an outlet are in fluid communication with the dilution chamber. The ambient air inlet is positioned opposite the outlet whereby suction through the outlet from outside the enclosure draws ambient air into the enclosure through the ambient air inlet to generate an airflow path from the ambient air inlet through the dilution chamber and out of the outlet. The dilution spacer may include an actuator inlet configured to securely releasably interengage a metered-dose inhaler actuator mouthpiece, or may include a receptacle having an actuator nozzle and configured to receive a metered-dose inhaler canister. A metered-dose inhaler plume entering the dilution chamber intersects the airflow path thereto and airflow along the airflow path entrains and redirects at least a portion of the metered-dose inhaler plume toward the outlet.

Abstract: The invention provides an inhalation device for enabling a user to inhale at a desired inspiratory flow rate and/or pressure, comprising a feedback system configured to indicate to a user by means of a signal during an inhalation maneuver whether an inhalation parameter, such as the inspiratory flow rate, is within a predefined target range. The signal may be an optical or a non-optical signal, such as a light signal, an acoustic signal, or a tactile signal.

Abstract: An electronic cigarette and fluid dispensing system (E-Cig FDS) that utilizes an electronic cigarette (e-cig) having an inner end, an outer end, and an outer surface with a first aperture and a second aperture, and a keyed fluid dispenser having a body with an inner surface, an outer surface, an open first end, and a second end. Located within the body at the first end is a plunger that can slideably move inside the body. Extending from the body's second end is an injector dimensioned to interface with the first aperture or second aperture. The fluid facilitates the smoking, or vaping, of the e-cig. A user can selectively choose if the fluid is safe, non-nicotine or nicotine-infused. The E-Cig FDS provides visual differentiation of the type of fluid that is being smoked, or vaped.

Abstract: A monitoring device includes a housing that is constructed and arranged to be removably attached to a drug delivery device for an inhaled drug. A color detector is operatively associated with the housing and constructed and arranged to detect an identifying color of at least a portion of the drug delivery device when the housing is attached to the drug delivery device and to output color information for use by a processor to, based on the detected color, identify information about the inhaled drug.

Abstract: A counter containing a first ring member having first indicia and a second ring member having second indicia, each of the first and second ring members being rotatable in increments about a common axis, one or both of the first and second indicia indicating a count; and a drive mechanism for rotating the first ring member and for rotating the second ring member after one or more predetermined degrees of rotation of the first ring member, wherein the drive mechanism contains a pawl-and-teeth mechanism which contains a first and second pawl engageable with a plurality of teeth, and wherein each of the first and second pawls contains a driving engagement face for engaging in a driving engagement with one of the plurality of teeth, and a sliding engagement face for sliding over one of the plurality of teeth.

Abstract: The invention of the present application relates to an apparatus to aid in administering inhaled pharmaceutical aerosol to a patient. The apparatus is used in conjunction with an aerosol delivery device. The apparatus comprises steps on the top and bottom of the apparatus, which when used aid the patient causes mandibular advancement, and opening of the mouth, causing opening of patient's airway, resulting in improved aerosol lung deposition. The invention also relates to a method of using such apparatus in a combination with an aerosol delivery device or a system, and to the mouthpiece of said apparatus.

Abstract: The present invention provides dose counter for displaying a count indication of the number or quantity of doses dispensed from or remaining in a container associated, in use, with the dose counter, comprising an indicator member comprising dose indicia and a priming indicator for prompting a user to carry out one or more priming actuations of the container. The priming indicator is initially arranged to at least partially overly the indicator member to thereby at least partially obscure viewing of the dose indicia of the indicator member until the one or more priming actuations of the container have been completed. The priming indicator is movable after the one or more priming actuations have been completed into a disposition where it no longer obscures viewing of the dose indicia of the indicator member. The invention also provides a dispensing apparatus comprising the dose counter.

Abstract: A metered dose inhaler (“MDI”) applicator is disclosed that includes a carrier, a housing, an adjuster and a lever. The carrier defines an aperture configured to receive a boot of a MDI. The housing is configured to be assembled with the carrier and to move in a vertical direction within the MID applicator relative to the carrier. The adjuster is configured to move between a locked position and an unlocked position, wherein when the adjuster is in the locked position, the adjuster is configured to prevent the carrier and the housing from moving in one or more directions relative to one another. The lever is pivotally connected to the housing and is configured to transfer a force applied to the lever to a canister of the MDI and to actuate the MDI to dispense an aerosolized medicine.

Abstract: An electronic smoking article includes a reservoir containing a liquid material and having an outlet, a capillary having a capillary inlet and a capillary outlet, the capillary inlet of the capillary in communication with the outlet of the reservoir, a heater operable to heat the capillary to a temperature sufficient to at least initially volatilize liquid material contained within the capillary, and a shuttle valve between the outlet of the reservoir and the capillary inlet. The shuttle valve is operable to prevent release of liquid material from the reservoir when the shuttle valve is in a closed position and is operable to release liquid material from the reservoir when the shuttle valve is in an open position.

Abstract: Medical devices, systems, and methods for pain management and other applications may apply cooling with at least one probe inserted through an exposed skin surface of skin. The cooling may remodel one or more target tissues so as to effect a desired change in composition of the target tissue and/or a change in its behavior, often to interfere with transmission of pain signals along sensory nerves. Alternative embodiments may interfere with the function of motor nerves, the function of contractile muscles, and/or some other tissue included in the contractile function chain so as to inhibit muscle contraction and thereby alleviate associated pain. In some embodiments, other sources of pain such as components of the spine (optionally including herniated disks) may be treated.

Abstract: An atomizing element for an electronic cigarette is provided, which includes: a porous body comprising an atomizing surface and a liquid absorbing surface; and a porous heating film formed on the atomizing surface. An electronic cigarette and an atomizing assembly including the same are also provided.

Abstract: A respiratory treatment device includes a housing enclosing a chamber, a chamber inlet configured to receive a flow of air into the chamber, a first chamber outlet configured to permit the flow of air to exit the chamber, and a second chamber outlet configured to permit the flow of air to exit the chamber. A vane mounted within the chamber is configured to rotate between a first position where the flow of air is directed to exit the chamber through the first chamber outlet, and a second position where the flow of air is directed to exit the chamber through the second chamber outlet. A blocking member disposed on the vane is moveable relative to the chamber inlet between a closed position where the flow of air through the chamber inlet is restricted, and an open position where the flow of air through the chamber inlet is less restricted.

Abstract: A kit is disclosed for supplying a cartridge of an inhaler article with liquid tobacco extract, the kit comprising an apparatus having means for extracting a liquid tobacco extract from a tobacco derived solid. The apparatus is adapted to deliver liquid tobacco extract to a cartridge and a cartridge adapted to receive liquid tobacco extract from the apparatus. An apparatus for supplying a liquid tobacco extract to a cartridge of an inhaler article is further disclosed. The apparatus has a housing, means for extracting a liquid tobacco extract from a tobacco derived solid and said housing is adapted to deliver liquid tobacco extract to a cartridge of an inhaler article. A related method of supplying a cartridge of an inhaler article with a liquid tobacco extract is further disclosed.

Abstract: A process for flushing a dispenser that dispenses liquids, especially perfumes, containing microcapsules. The dispenser has a first reservoir for a first composition containing microcapsules and a second reservoir for a second composition containing a volatile solvent. The dispenser also has a swirl chamber and a premix chamber. The process simultaneously pumps the first and second compositions into the premix chamber and then into the swirl chamber. The pumping of the first composition is halted while the pumping of the second composition continues, and this provides an extra volume of the volatile solvent, which flushes the dispenser to prevent clogging by the microcapsules.

Abstract: An apparatus and system that efficiently and effectively delivers a sanitizing fluid to ducts in the form of a fog or mist is described. A canister that contains a liquid sanitizing solution is attached to a compressor and includes a straw that has an internal passageway that extends into the liquid and a venturi tube above the level of the liquid that connects with the internal passageway in the straw. The headspace above the liquid in the canister is pressurized, causing fluid to flow upwardly in the straw when a trigger is depressed, drawing fluid upwardly in part by the venturi. As the liquid passes the venturi the pressurized air that is flowing into the venturi causes the fluid to form a fine mist. The mist, under pressure from the compressor, is routed into a flexible delivery tube that has been previously positioned in a duct system. The terminal end of the tube has an atomizing ball attached thereto and the atomizing ball has a series of orifices through which the misted, atomized fluid is delivered.

Abstract: A method of assembling a tubular simulated cigarette, the method comprising providing an elongate hollow housing having an inhaling end and a refill end; inserting an outlet valve tube, a dip tube and a support from the refill end so that the support supports the proximal end of the dip tube in the housing; inserting a refill valve into the refill end and fixing it in place to form a composition reservoir with the dip tube placing the reservoir in fluid communication with an outlet orifice when the outlet valve tube is open; inserting a valve element into a recess in the side of the housing so that the valve element is positioned to selectively close the outlet valve tube; inserting a breath operated valve actuation mechanism laterally into the recess; and applying a cover to the recess.

Abstract: A device for cycling a component between a first condition and a second condition includes an element and a reset apparatus connected to and driven by the element. The element is formed from a shape memory alloy, wherein the alloy is transitionable between a martensite crystallographic phase and an austenite crystallographic phase in response to a thermal energy source. The apparatus is actuatable by the element from an initial state in which the alloy has the martensite phase and the component is in the first condition, to an actuated state in which the alloy has the austenite phase and the component is in the second condition. The apparatus is resettable from the actuated state to a reset state in which the alloy transitions from the austenite to the martensite phase while the component is in the first condition, and further resettable from the reset state to the initial state.

Abstract: The invention relates a metering device for fluids from a containment volume. The metering device is a means to dispense metered volumes of fluids such as detergents, medicaments, lotions and the like. The invention further provides a container for fluid material to be dispensed in metered doses.

Abstract: Inventive embodiments disclosed herein refer to a fragrance dispenser. The fragrance dispenser includes an enclosure having a base and a top portion, including a spray actuator. The fragrance dispenser also includes two or more bottles enclosed in the enclosure, each bottle having a top pump portion and a bottom portion. Two or more fragrances are enclosed in the two or more bottles, one fragrance per bottle. Two or more pumps, one pump per bottle are positioned within the pump portion of each of the two or more bottles. A manifold includes connector passages that connect all of the pumps to the spray actuator. At least two cams, both of which are enclosed by the enclosure are positioned adjacent the base of the enclosure, wherein the two cams together contact all of the two or more bottles, wherein movement of the cams produces movement of one or more of the pumps up or down. The fragrance dispenser also includes one or more dials for adjusting the position of each of the cams.

Abstract: Provided is a method for preventing or treating inflammation and associated states (e.g. infection, hypersensitivity, pain) by administering a therapeutically effective amount of an oxidative reduction potential (ORP) water solution that is stable for at least about twenty-four hours. The ORP water solution administered in accordance with the invention can be combined with one or more suitable carriers and can be administered in conjunction with one or more additional therapeutic agents.