Abstract: A device sized and shaped for alleviating organ prolapse when inserted into a vagina, comprising: (a) an adjustably flexible, substantially planar ring; (b) a telescoping locking mechanism extending in a central axis, but within the plane of the ring, from a first side of the ring to a second side of the ring, comprising, (i) a first element extending from a side of the ring including an elastic diamond shaped snap, and, (ii) a second element extending from a second side of the ring, opposite the first element, including at least one window configured as a counterpart to the snap, wherein the device is configured to be in an expanded, treatment rendering state when the snap is released into the window and a reduced profile state when the snap is not in the window.

Abstract: An intragastric device includes an elongated member having a proximal end and a distal end and an anchor connected to the elongated member. The anchor includes a stem, a first arch and a second arch, and a curvilinear element. The stem includes a proximal end and a distal end. The distal end of the stem is attached to the proximal end of the elongated member. Each arch has first and second ends and a proximal peak therebetween. The first end of each arch is attached to the proximal end of the stem, and the second end of each arch extends radially away from the stem. The curvilinear element connects the second end of the first arch to the second end of the second arch.

Abstract: A surgical device comprising: an applicator; a clamp comprising a clasp and a tether; and optionally an anchor.

Abstract: Devices and methods for vaginal insertion are disclosed.

Abstract: A fornix manipulator includes a collar and stabilizer. The collar has a first end and a second end, the second end having an opening and diameter greater than the first end and the first end having an opening to receive a cervix into the collar. The stabilizer has a base portion defining a guide hole and a plurality of prongs extending from the base portion to contact the first end of the collar.

Abstract: A convenient and highly accurate intravaginal device with wireless sensors for monitoring fertility and sexual health of humans and animals is proposed. Sensors in the intravaginal device measure fertility and sexual health and via wireless transmitter send this information to a terminal on which the information is processed and displayed in convenient form.

Abstract: A microbicidal delivery system including: a microbicidal composition including a microbicidal compound including a dendrimer including one or more surface groups of formula (IV); a microbicidally active derivative thereof, or pharmaceutically acceptable salt or solvate thereof; and a carrier, excipient or diluent therefor; and a prophylactic device; the microbicidal composition being carried on a surface of the prophylactic device and being compatible therewith.

Abstract: A cervical cap is provided having an annular rim with a first predetermined thickness. An annular collar extends from the rim and has a second predetermined thickness that is greater than the first predetermined thickness. A dome shaped wall extends from the collar and has a third predetermined thickness that is less that the second predetermined thickness. A method of forming a cervical cap is provided that includes the steps of preparing a three part mold, injecting material into the mold, and curing the material in the mold to form the cervical cap.

Abstract: A protective shield. The protective shield is provided in a generally cupped structure sized to accommodate and shaped with sufficient volume to receive therein adult human female genitalia. The protective vaginal shield includes a soft, flexible outer lip that is generally configured in the shape of an arcuate section made through an ovoid shape substantially along the longitudinal axis thereof. Extending inwardly and downwardly from the outer lip are outer sloping sidewalls. A longitudinally extending nose portion is provided. Inner sloping sidewalls extend from the outer sloping sidewalls to the longitudinally running nose portion. In one embodiment, the inner sloping sidewalls comprise a pair of opposing concave shaped structures, to provide a secure handle grip. In an embodiment, the protective shield may be provided in a disposable material.

Abstract: An endocervical seal has a sleeve with a passageway for receiving an intrauterine interventional or diagnostic tool. The sleeve has a coaxially disposed outer balloon with a distal portion configured to inflate in a cervical os and a proximal portion configured to inflate in a cervical canal.

Abstract: Medical devices and related methods are disclosed for delivering an implant into the body of a patient. The devices include a damping assembly having an internal chamber with a varying inner diameter, and a piston slideably disposed therein. The piston is operably connected with a catheter portion such that movement of the piston is associated with concurrent movement of the catheter for implant delivery. The varying inner diameter of the damping assembly results in a decrease in damping force during implant delivery, thus providing a substantially constant velocity of implant delivery.

Abstract: The presently-disclosed subject matter provides compositions and methods for treating a cancer by providing a composition comprising a biocompatible polymeric matrix incorporating an effective amount of a phytochemical agent, a combination of phytochemical agents, or a phytochemical agent and a chemotherapeutic agent. Further, provided is a device for uterine cervical insertion for local delivery.

Abstract: Protective shield and protective or ornamental cover for protecting the vulva and labia minora of a female. The protective shield is shaped to conform to the outer shape of the labia minora and protects the vulva of a female user.

Abstract: Protective shields with and without retaining wings and shield cover for protecting the vulva and labia minora of a female. The protective shield is shaped to conform to the outer shape of the labia minora and may include retaining wings which hold the shield in place. An outer cover may be installed on the shield for protective and ornamental purposes.

Abstract: Uterine cervical cancer Computer-Aided-Diagnosis (CAD) according to this invention consists of a core processing system that automatically analyses data acquired from the uterine cervix and provides tissue and patient diagnosis, as well as adequacy of the examination. The data can include, but is not limited to, color still images or video, reflectance and fluorescence multi-spectral or hyper-spectral imagery, coherent optical tomography imagery, and impedance measurements, taken with and without the use of contrast agents like 3-5% acetic acid, Lugol's iodine, or 5-aminolevulinic acid. The core processing system is based on an open, modular, and feature-based architecture, designed for multi-data, multi-sensor, and multi-feature fusion. The core processing system can be embedded in different CAD system realizations.

Abstract: An intravaginal uterine artery occlusion device is used for treating uterine disorders such as fibroids, dysfunctional uterine bleeding, postpartum hemorrhage and the like. A occlusion device has a cervical receptacle with an open distal end for receiving the patients uterine cervix, an elongated shaft having a distal end secured to the closed proximal end of the cervical receptacle, and an inner lumen extending to the distal end of the shaft. The patient's uterine cervix is held within the interior of the receptacle by the application of a vacuum to the interior of the receptacle through the inner lumen of the shaft while the leading edge(s) of the cervical receptacle press against the patient's vaginal fornix to occlude the uterine artery. A blood flow sensor may be provided on the leading edge of the receptacle to aid in locating a uterine artery and to monitor blood flow through the uterine artery.

Abstract: A method is provided of forming a cervical cap in situ, i.e., within a patient's body, which cap will substantially completely conform to the shape of the patient's cervix, allowing the cap to be left in place over an extended period of time. The method of the invention includes the steps of positioning a snugly fitting rim member around the patient's exocervix, mounting a shell member, having an aperture, onto the rim member such that the rim member, shell member and exocervix define a cavity, and injecting a curable material through the aperture to substantially fill the cavity. After the curable material is allowed to harden, the entire assembly is removed from the patient and the shell removed from the cured material.

Abstract: A cervical collection device (20) for collecting uterine and cervical secretions for medical diagnostic purposes. The cervical collection device (20) is placed over the cervical opening (14). Collection device (20) includes an outer elastomeric receptacle (22) of a hemispherical shape having a collection capsule or pad (26) fitting thereon. Collection pad (26) includes an inner layer or core (28) of absorbent material and an outer water-resistant cover (32). Collection member (26) has an outer convex surface conforming to the inner surface of the elastomeric receptacle (22). Receptacle (22) has an outer rim (24) arranged for fitting over the cervical opening (14) for removable securement of collection device (20) to a user. Inner layer (28) may be formed of various materials and impregnated with selected substances.

Abstract: A method is provided of forming a cervical cap in situ, i.e., within a patient's body, which cap will substantially completely conform to the shape of the patient's cervix, allowing the cap to be left in place over an extended period of time. The method of the invention includes the steps of positioning a snugly fitting rim member around the patient's exocervix, mounting a shell member, having an aperture, onto the rim member such that the rim member, shell member and exocervix define a cavity, and injecting a curable material through the aperture to substantially fill the cavity. After the curable material is allowed to harden, the entire assembly is removed from the patient and the shell removed from the cured material.

Abstract: A catheter device is described for the localized introduction of pharmaceutical material into the uterine cervix and the upper vagina. In one embodiment the catheter device comprises a flexible tube having a port at the proximal end and a rounded closed tip and an aperture away from the tip at the distal end. A diaphragm having a hole through which the tube may pass is used to seal off the cervix and upper vagina from the lower vagina, and a syringe is used to administer the pharmaceutical material through the port in the flexible tube. In a second embodiment two ports are provided in the flexible tube, enabling a flushing material to be ejected into the tube after the pharmaceutical material, thus ensuring that the entire dose of pharmaceutical material is delivered to the cervix and the upper vagina.

Abstract: A cervical cell and fluid collector includes a substantially disc-shaped main body made of a high-density, non-absorbent, non-fibrous, biologically inert polyurethane foam. A porous membrane is mounted in a mainly concave collection recess in the main body. When the collector is in place adjacent to the cervix of a patient, cells and fluids adhere to the outer surface of the membrane. A layer of a cell-moistening material or agent is provided between the membrane and the inner surface of the recess; the cell-moistening material is preferably a pre-hydrated polymer gel that releases water during cell collection for moistening collected cells through the pores of the membrane when the cells are adhered to the outer surface of the membrane. The main body has an inward-slanting annular lip defining the recess and resiliently holding the membrane. The collector may remain in the vaginal cavity of the patient for up to at least 24 hours.

Abstract: A contraceptive cervical cap or form therefor, and a method for producing the same.

Abstract: A porous pouch or pad-retaining means in a vaginal diaphragm or a cervical cap, specially designed to securely and removably house a foam pad which pad will dispense Nonoxynol-9 or other spermatostatic/lymphocytostatic chemicals where the chemicals will exert maximal effect during hydrostatic pressure changes occurring during intercourse.

Abstract: A contraceptive cervical cap or form therefor, and a method for producing the same.

Abstract: A device and method for intravaginal, barrier-type prevention of conception and infection by sexually-transmitted diseases based upon a barrier-type device including a flexible cervical dome having a continuous fornical rim defining an opening into the dome and a continuous, annular, vaginal brim which circumscribes and is attached to the cervical dome at the fornical rim. The vaginal brim is reverse-folded from the fornical rim, and has a dimension which continuously increases with circumferential symmetry from an anterior vaginal extension of the brim to a posterior vaginal extension of the brim which is diametrically opposite the anterior vaginal extension. The fornical rim is characterized in having a lip which extends inwardly from the opening toward the centerline of the dome. The brim has a curvature in a direction away from the dome.

Abstract: A cervical cap for covering a portion of the cervix uteri in order to prevent migration of sperm from the vagina into the cervical canal to thereby prevent conception. The cervical cap has an open end portion, a dome-shaped portion, preferably sealed, disposed opposite the open end portion, and a ridged section designed to grip the cervix to secure the cap. In the preferred embodiments, the ridged section has a plurality of substantially parallel ring-shaped ridges formed on the interior surface of the cap. In an alternate embodiment, a helical-shaped ridge is formed on the interior surface of the cap and extends from the rim to the dome portion, progressively narrowing in width.

Abstract: A disposable cervical cap has a thin, form-assuming pliable dome with an integrally-molded resilient retaining rim. The rim has a bevelled outer shoulder and contains an annular groove on its inner surface. The inner groove and rim define two ascending lips on the inner surface of the rim which prevent dislodgement of the cap from the cervix. The cervial cap includes a set of tabs on its outer surface to assist in positioning and placement of the cap and further includes a loop for removing the cap after use.

Abstract: A disposable cervical cap has a thin, form-assuming pliable dome with an integrally-molded resilient retaining rim. The rim has a bevelled outer shoulder and contains an annular groove on its inner surface. The inner groove and rim define two ascending lips on the inner surface of the rim which prevent dislodgement of the cap from the cervix. The cervical cap includes a set of tabs on its outer surface to assist in positioning and placement of the cap and further includes a loop for removing the cap after use.