Abstract: The present invention relates to a male contraception apparatus for obtaining temporary sterility of a male mammalian individual. The apparatus has an implantable restriction device adapted to restrict vas deference in the region downstream the ampulla during a controlled period in order to preventing sperms to reach the urethra. Further, the apparatus has a control device for controlling the operation of the restriction device.

Abstract: A tissue fusing clamp comprises a pair of components pivotably attached, having a component end with a finger loop for manipulation of the components, and each component having a fusing end comprising fusing jaws that are able to be motivated towards one another into a closed position. A depressor depresses tissue between the tissue areas to be fused, resulting in a tightening of the tissue after fusing. The fusing jaws may each comprise a fusing element, such as an ultrasonic transducer or laser, that is in electrical communication with a fusing circuit for providing electrical power to the fusing element as desired by a user. The fusing circuit may be controlled by use of a foot switch or other controller that may be manipulated by the user when it is desired to activate the fusing elements.

Abstract: The present methods, systems, and devices relate to an occlusion device for blocking a biological tube, the biological tube being prone to a peristaltic wave having a wave length, and where the occlusion device comprises at least two sections, where each section is connected by at least one narrowing to at least one other section. The occlusion device is of an elastic material, and each section is configured to deform when a force is applied by the peristaltic wave, and the length of at least one of the at least two sections corresponds substantially to the wave length of the peristaltic wave in the biological tube, so as to absorb the peristaltic wave. The methods, systems, and devices relates to reversible contraception of female and/or male gendered species intervening with biological tube, which are responsible for transportation of fertility fluids, such as the transportation of spermatozoes or oocytes in for example the human reproductive system.

Abstract: Conventional vasectomy techniques suffer from a number of potential complications, including, for example, a substantial risk for the development of hematomas, and swelling, and post-surgical pain, a potential for spontaneous duct reconnection and undesired resumption of fertility, a need for a highly skilled surgical professional, as well as a long recovery period, accompanied by severe limitations on post-surgical activity. The vasectomy methods of the present invention reduce and/or minimize contact with sensory nerves located on the distal side of the vas deferens, particularly the distal region of the outer vas deferens sheath, so as to minimize nerve damage and the post-surgical pain associated therewith.

Abstract: A clip applier may be configured to apply a surgical clip to tissue. The clip applier may include a first jaw member, a second jaw member, and a stabilizing member, each configured to engage the surgical clip. The stabilizing member may be configured to move longitudinally with respect to the clip applier from a first position at least partially between the first and second jaw members to a second position at least partially between the first and second jaw members. The longitudinal movement of the stabilizing member may be constrained to longitudinal movement between the first and second positions. The stabilizing member may include first and second sidewalls on a distal portion, where the first and second sidewalls are configured to stabilize the surgical clip in a lateral direction. The clip applier may include a hinge pin received in a longitudinal channel of the stabilizing member.

Abstract: An implant for occluding a flow through a vessel may comprise a body member having a first end portion, a second end portion, and an intermediate rod portion extending between the first end portion and the second end portion and a mesh having base layer and a plurality of micro-pillars extending from a first surface of the base layer. The mesh may be disposed about at least a portion of the body such that the micro-pillars extending generally radially outward from the body member. The plurality of micro-pillars may be configured to extend into an adjacent tissue.

Abstract: The invention relates to a device for treating blood flow in an internal wound, including a handling member connected to a series of successively narrower tubes, each tube including a liquid-expandable article. The tubes can be pivotably connected to each other, allowing the tubes to conform to the contours of the wound, or fixed together. The tubes can be encased in a liquid-soluble layer that keeps the liquid-expandable article sequestered from liquids. The stepwise-tapering profile of the device allows for its insertion into the internal wound with little or no resistance until fully seated. Upon encountering liquids within the wound, the liquid-soluble layer can dissolve to expose the liquid-expandable article. When exposed to the wound liquids, the liquid-expandable element can expand in volume, providing compressive pressure against internal wound surfaces and minimizing blood loss. The tubes and the liquid-expandable element can include therapeutic agents for treating the wound.

Abstract: A fastener delivery tool is disclosed. An example fastener delivery tool comprises a sheath assembly including a sheath and a position retention member and a retraction assembly including a cover and a retractor member. The cover includes a lumen extending therein. The fastener delivery tool also includes and a handle assembly coupled to a proximal end of the sheath assembly, the handle assembly including a housing and an actuation member. Further, the sheath assembly extends through the lumen of the cover and the retractor member is configured to move relative to the handle between a first position in which the sheath assembly is disposed within a distal portion of the cover and a second position in which the sheath assembly extends out of the distal portion of the cover. Additionally, actuation of the actuation member moves the retractor member from the first position to the second position.

Abstract: A urethral plug having a plug body, a lanyard and a stopper. The plug body having a leading end shaped to spread tissue at the urethral, a central portion; a trailing end tapering down from the central portion, and a sealing ring encircling the central portion. The plug body is shaped so that when positioned within the urethra the plug body is retained within the urethra, to restrict urine flow within the urethra past the plug body.

Abstract: Apparatus is provided that includes a casing, shaped to define a cavity, and one or more openings in the casing, in which openings one or more sutures are disposable; and a core, disposed in the cavity, and shaped to define a lumen in which the sutures are disposable. The apparatus has an unlocked configuration in which the sutures are disposable within and slidable through the openings and the lumen, and a locking configuration in which the sutures are inhibited from sliding through the openings and the lumen. The apparatus is movable from the unlocked configuration to the locking configuration, and is configured such that, when the sutures are disposed within the openings and the lumen, and the apparatus moves from the unlocked configuration to the locking configuration, the apparatus cuts the sutures at a cutting site, and becomes coupled to the sutures at a coupling site.

Abstract: A system for monitoring the target tissue during a tissue sealing procedure is disclosed. The system includes a forceps having opposing jaw members movable from a first position in spaced relation relative to one another to at least one subsequent position wherein the jaw members cooperate to grasp the tissue therebetween. Each of the jaw members includes a sealing member. The system also includes a generator coupled to the sealing members so that therapeutic energy is delivered to the target tissue. The generator includes an output stage configured to generate therapeutic energy and a microwave detector configured to measure reflected and/or absorbed microwave signals. The monitored microwave signals may be either the therapeutic energy signal or a separate non-therapeutic microwave monitoring signal. The generator also includes a controller operatively coupled to the microwave detector.

Abstract: A contraceptive or occlusion system for restricting and later opening up a reproductive tract or lumen of the vas deferens. The system is adapted to be reversible after implantation, including implantation on, around or within the vas deferens. A method and system to reconnect a severed body lumen, such as the vas deferens, is also provided.

Abstract: A system includes an adjustable implant configured for implantation internally within a subject and includes a permanent magnet configured for rotation about an axis of rotation, the permanent magnet operatively coupled to a drive transmission configured to alter a dimension of the adjustable implant. The system includes an external adjustment device configured for placement on or adjacent to the skin of the subject having at least one magnet configured for rotation, the external adjustment device further comprising a motor configured to rotate the at least one magnet and an encoder. Rotation of the at least one magnet of the external adjustment device effectuates rotational movement of the permanent magnet of the adjustable implant and alters the dimension of the adjustable implant. Drive control circuitry is configured to receive an input signal from the encoder.

Abstract: A system includes an adjustable implant configured for implantation internally within a subject and includes a permanent magnet configured for rotation about an axis of rotation, the permanent magnet operatively coupled to a drive transmission configured to alter a dimension of the adjustable implant. The system includes an external adjustment device configured for placement on or adjacent to the skin of the subject having at least one magnet configured for rotation, the external adjustment device further comprising a motor configured to rotate the at least one magnet and an encoder. Rotation of the at least one magnet of the external adjustment device effectuates rotational movement of the permanent magnet of the adjustable implant and alters the dimension of the adjustable implant. Drive control circuitry is configured to receive an input signal from the encoder.

Abstract: A surgical instrument for performing water jet surgical operations comprises a nozzle that can be moved via a hydraulic actuator out of a retracted or passive position into a moved-forward or active position. The actuation is accomplished using hydraulic fluid that is supplied to the instrument head via a tube and/or hose. The fluid (e.g., a sodium chloride solution) that is to be injected into the tissue can be used as the hydraulic fluid that is supplied to the nozzle. High-frequency (HF) current can additionally be applied to the nozzle. The HF current can be conducted to the nozzle via a line extending through the fluid conducting element or via the electrolyte present therein.

Abstract: Methods for the synthesis and use of several variations of styrene maleic acid-based polymers and the hydrogel tissue bridges that can be formed from such polymers. Specifically, a method is disclosed for synthesizing a styrene maleic acid-based polymer that can be dissolved in DMSO and injected into the vasa deferentia of male subjects, creating a hydrogel tissue bridge. This hydrogel tissue bridge can occlude the vas deferens, thus forming an effective male contraceptive. Additionally, this male contraceptive can be reversed by injecting the lumen of the vas deferens with a basic buffer solution to dissolve and remove the hydrogel tissue bridge.

Abstract: An occluding system is provided that can include a first occluding device (e.g., secondary occluder) and a second occluding device (e.g., primary occluder). Providing two devices can better promote effective occlusion within the body lumen and facilitate advantageous occlusion stages, such as initial and long-term occlusion stages. In various embodiments, the two occluding devices are in operative communication with one another, such that the second occluding device is adapted to couple with or slide along a tail portion of the first occluding device.

Abstract: A contraceptive or occlusion system for restricting and later opening up a reproductive tract or lumen of the vas deferens. The system is adapted to be reversible after implantation, including implantation on, around or within the vas deferens. A method and system to reconnect a severed body lumen, such as the vas deferens, is also provided.

Abstract: A method of treating prolapse of a vagina includes securing a base of a support to tissue by inserting an anchor into the tissue, the anchor coupled to the support via an interconnecting member, securing a leg of the support that extends from the base of the support to a cuff of the vagina, and adjusting elevation of the cuff of the vagina relative to a patient's sacrum by sliding the interconnecting member relative to the anchor.

Abstract: A device and method of using the device for contraception or sterilization and particularly for reversible contraception by occluding a reproductive lumen to prevent the passage of reproductive cells through the lumen for a desired period of time until the patient wishes to become fertile again and then be reopened. The occluding member preferably comprises a tubular framework formed from a shape memory material configured to be implanted in a reproductive lumen. The occluding member is implanted within a body lumen, secured to the wall of the reproductive lumen and then collapsed to collapse the wall and occlude the lumen. Alternatively, the occluding member may be collapsed upon a solid plug. The closure of the reproductive lumen may be reversed by introducing a balloon catheter and by a series of inflations of the balloon reexpanding the collapsed occluding member or by removing the plug.

Abstract: The invention described is directed to an intracorporeal occluding device having elements with non-traumatic ends and devices, systems and methods for occluding the lumens of anatomical passageways and/or for delivering drugs or other substances to the bodies of human or animal subjects.

Abstract: A valve assembly adapted for implantation into the vas deferens of a male patient. The valve assembly is operable in a first mode to block the flow of sperm and in a second mode to permit the flow of sperm. The surgeon is permitted to shift the valve assembly between its first and second functional modes by moving a moveable valve member. The valve assembly includes a valve retention feature for releasably retaining the valve member is a selected position associated with each of the two distinct functional modes.

Abstract: The invention describes methods and apparatus for creating permanent occlusion of body lumens such as the fallopian tubes. The methods and apparatus use non-surgical approaches to deliver permanent implants which create acute occlusion of desired body lumens which resolve to permanent occlusions of the lumens.

Abstract: An energy delivery probe is provided that may include any of a number of features. One feature of the energy delivery probe is that it can apply energy to tissue, such as a duct, to shrink, damage, or occlude the duct. In some embodiments, the energy can be applied with a vapor media. In some embodiments, the duct can be a ductus deferens or an ejaculatory duct of the male reproductive system. Another feature of the energy delivery probe is that it can utilize an inflatable member to form a seal to contain the vapor media. Methods associated with use of the energy delivery probe are also covered.

Abstract: The invention described is directed to an intracorporeal occluding device having elements with non-traumatic ends and devices, systems and methods for occluding the lumens of anatomical passageways and/or for delivering drugs or other substances to the bodies of human or animal subjects.

Abstract: An on/off fertility regulator device in the form of a male vas deferens or female fallopian tube bypass mounted device incorporating an open/close valve actuator. A separate handheld controller is positioned above the skin and in proximity to the previously implanted regulating device. Wireless energy transfer receiver circuitry is built into the device and, upon receiving a electric generated signal the inductive circuit printed coil activates the actuator in order to actuate any of a clamp, ball, globe or flow interrupter associated with a bypass connection tube associated with each of the pair of vas deferens. As a result, passage of semen from the seminal vesticle (or alternatively eggs through the fallopian tube) can be instantly interrupted or permitted in on/off fashion as a viable alternative to the user undergoing an irreversible vasectomy operation.

Abstract: The invention described is directed to an intracorporeal occluding device having elements with non-traumatic ends and devices, systems and methods for occluding the lumens of anatomical passageways and/or for delivering drugs or other substances to the bodies of human or animal subjects.

Abstract: A reversible vasectomy device includes a first and a second connector piece for attachment to the severed ends of the vas deferens. Each connector piece has an outer vas deferens attaching end, an opposite inner end, and a passage from the outer to the inner end. A midpiece has end portions that are connectable to the inner ends of the connector pieces, a passage in one end portion and a vent from the passage to an exterior surface. When the connector pieces are connected to the end portions, the passage in one of the connector pieces is in fluid communication with the vent, but is not in fluid communication with the passage in the other connector piece.

Abstract: A medical device is provided which forms a physical barrier between the two ends of a cut vas during a vasectomy procedure, comprising a biodegradable, polymeric cap that is applied over at least one prostatic end of the vas, the cap including a fastener for preventing premature dislodgement.

Abstract: The present invention relates to a male contraception apparatus for obtaining temporary sterility of a male mammalian individual. The apparatus comprises an implantable restriction device adapted to restrict vas deference in the region downstream the ampulla during a controlled period in order to preventing sperms to reach the urethra. Further, the apparatus comprises a control device for controlling the operation of the restriction device.

Abstract: Contraceptive and/or sterilization methods and devices are disclosed which may improve the speed of tubal occlusion and mechanisms for anchoring for a contraceptive device. In accordance with some embodiments, improvements may be made to the delivery catheter to induce trauma and create faster tubal occlusion, improvements may be made to the occlusion device to prevent migration and induce trauma, and improvements may be made to the occlusion device to reduce the total volume of in-growth required compared to conventional expansive occlusion devices.

Abstract: An apparatus for controlling a flow of fluid and/or other bodily matter in a lumen formed by a tissue wall of a patient's organ comprises an implantable constriction device for gently constricting (i.e. without substantially hampering the blood circulation in the tissue wall) at least one portion of the tissue wall to influence the flow in the lumen, and a stimulation device for stimulating the wall portion of the tissue wall. A control device controls the stimulation device to stimulate the wall portion, as the constriction device constricts the wall portion, to cause contraction of the wall portion constricted by the constriction device to further influence the flow in the lumen. The apparatus can be used for restricting or stopping the flow in the lumen, or for actively moving the fluid in the lumen, with a low risk of injuring the organ.

Abstract: An on/off fertility regulator device in the form of a male vas deferens or female fallopian tube bypass mounted device incorporating an open/close valve actuator. A separate handheld controller is positioned above the skin and in proximity to the previously implanted regulating device. Wireless energy transfer receiver circuitry is built into the device and, upon receiving a electric generated signal the inductive circuit printed coil activates the actuator in order to actuate any of a clamp, ball, globe or flow interrupter associated with a bypass connection tube associated with each of the pair of vas deferens. As a result, passage of semen from the seminal vesticle (or alternatively eggs through the fallopian tube) can be instantly interrupted or permitted in on/off fashion as a viable alternative to the user undergoing an irreversible vasectomy operation.

Abstract: There is provided a method for controlling a flow of fluid and/or other bodily matter in a lumen formed by a tissue wall of a patient's organ. The method comprises gently constricting (i.e., without substantially hampering the blood circulation in the tissue wall) at least one portion of the tissue wall to influence the flow in the lumen, and stimulating the constricted wall portion to cause contraction of the wall portion to further influence the flow in the lumen. The method can be used for restricting or stopping the flow in the lumen, or for actively moving the fluid in the lumen, with a low risk of injuring the organ. Such an organ may be the esophagus, stomach, intestines, urine bladder, urethra, ureter, renal pelvis, aorta, corpus cavernosum, exit veins of erectile tissue, uterine tube, vas deferens or bile duct, or a blood vessel.

Abstract: Apparatus and methods for performing vasectomies are disclosed. In preferred embodiments, a clamp has a set of jaws, the distal ends of which terminate in a partial or completely circular structure that is essentially a split ring. The ring may include pointed tips structured to pierce the vas deferens. The tips engage opposing sides of the vas deferens. Various embodiments of the toothed clamps may be preferred for “open” versus “closed” vasectomies.

Abstract: A sperm collecting apparatus is provided and includes a container having a non-cylindrical container main unit whose one end face in a longitudinal direction is open and a cap that is attachable the container main unit. A core member made from a gel-like material, which is located in the container main unit and has an insertion room extending to an inner portion of the core member from an insertion port at one end face in the core member. A sponge layer which is interposed between the core member and an inner wall of the container main unit, the container main unit is a non-cylindrical member whose intermediate portion in a longitudinal direction thereof has an outer diameter smaller than those in both end portions.

Abstract: An occluding system is provided that can include a first occluding device (e.g., secondary occluder) and a second occluding device (e.g., primary occluder). Providing two devices can better promote effective occlusion within the body lumen and facilitate advantageous occlusion stages, such as initial and long-term occlusion stages. In various embodiments, the two occluding devices are in operative communication with one another, such that the second occluding device is adapted to couple with or slide along a tail portion of the first occluding device.

Abstract: There is provided a method for controlling a flow of fluid in the vas deferens in order to obtain a controlled male contraception. The method comprises gently constricting (i.e., without substantially hampering the blood circulation in the tissue wall) at least one portion of the tissue wall to influence the flow vas deferens, and stimulating the constricted wall portion to cause contraction of the wall portion to further influence the flow in the vas deferens. The method can be used for restricting or stopping the flow in the vas deferens, or for actively moving the fluid in the vas deferens, with a low risk of injuring the organ.

Abstract: An occlusion clip for permanently occluding a bodily vessel, such as the vas deferens. The occlusion clip has a first leg, a second leg, joined on their proximal ends by a spring coil. The spring coil provides a biased torsional force to the first leg and the second leg, to force them into a closed position. The first leg and the second leg have on their distal ends a vessel occlusion portion that occludes the targeted vessel when the clip is in a closed position.

Abstract: A medical device including a body portion configured and dimensioned to be associated with a vessel of a patient and a responsive component associated with the body portion wherein the responsive component is switchable between a first configuration and a second configuration.

Abstract: A medical device or system may include an anchor capable of grasping tissue, rotating the tissue, and/or occluding a space in communication with the tissue. A method for occluding a space within a patient may include grasping tissue, rotating the tissue, and/or occluding a space in communication with the tissue.

Abstract: A male contraception implant for insertion into the vas deferens of a patient includes a tubular member having an internal bore for receiving a guide wire, a bulbous head portion for anchoring the implant and to facilitate its removal in a contraception reversal procedure, a flexible neck portion attached to the enlarged head portion, and a main body portion having three widened segments for occluding the vas deferens. An implantation tool includes an elastic C-shaped slotted ring for holding an externalized portion of the vas deferens during the delivery of the implant.

Abstract: A medical device is provided which forms a physical barrier between the two ends of a cut vas during a vasectomy procedure, comprising a biodegradable, polymeric cap that is applied over at least one prostatic end of the vas, the cap including a fastener for preventing premature dislodgement.

Abstract: An intra-vas deferens occlusive device for male contraception includes an axial filament having a small identification ball at the proximal end thereof, which remains outside the vas deferens but which is joined to an anchoring filament and to two occlusive bodies essentially in the form a clamp. The occlusive bodies are joined in a first embodiment by the interconnecting filament and in a second embodiment by the vertices thereof, such as to form a peripheral slit. Both embodiments terminate in a flange which is assembled to a washer pivot of the ad hoc insertion and implantation needle of the device.

Abstract: An absorbable and expandable closure member used to occlude or exclude a body lumen or cavity, such as a blood vessel, fallopian tube, duct, aneurysmal sac, etc., comprising a closure member comprising one of more sheets of a biomaterial that are rolled, stacked, or folded to form a multilayer construct of a generally cylindrical configuration for deployment through a delivery system, either as a singularly or part of a multiplicity of closure members. The biomaterial is derived from a source material, such as small intestinal submucosa or another remodelable material (e.g., an extracellular matrix) having properties for stimulating ingrowth of adjacent tissue into the biomaterial deployed within the bodily lumen. The closure member is deployed to the bodily lumen from a delivery sheath, cartridge, and/or over a inner guiding member, such as a wire guide or catheter.

Abstract: Conventional vasectomy techniques suffer from a number of disadvantages, including, for example, a substantial risk for the development of hematomas and swelling, a potential for spontaneous regeneration and undesired resumption of fertility, a need for a highly skilled surgical professional, as well as a long recovery period, accompanied by severe limitations on post-surgical activity. The invention disclosed herein overcomes the disadvantages and deficiencies of the prior art by providing a rapid, reliable, less invasive male sterilization procedure as well as a vasectomy device and kit for use therewith.

Abstract: An external incontinence clamp for stopping involuntary voiding of urine is provided. The clamp includes a first rigid member having opposed ends, each end defining a passage extending therethrough, a second rigid member having opposed ends, each end defining a passage extending therethrough, and two pins of generally u-shape. The pins are adapted to be received by the passages defined by the ends of the first rigid member and of the second rigid member so as to secure the first rigid member in a spaced and generally parallel relationship to the second rigid member. The penis is positioned between the first and second members so that the underside of the penis is in contact with the second member and the top surface of the penis is in contact with the first member, thereby stopping involuntary voiding of urine. A clamp kit includes a plurality of pins of different width to vary the force applied to the penis.

Abstract: Certain embodiments include a method of improvising radiological outcomes by introducing a filler to between a first tissue location and a second tissue location to increase a distance between the first tissue location and the second tissue location, and administering a dose of radioactivity to at least the first tissue location or the second tissue location. Collagen and hyaluronic acid are examples of fillers. Certain embodiments include a medical device having a biocompatible, biodegradable filler material, wherein the device comprises at least a portion that has a shape that substantially conforms to Denovillier's space between the rectum and prostate. Certain embodiments include a kit, the kit comprising a filler and instructions for placing the filler between a first tissue location and a second tissue location to increase a distance between the first tissue location and the second tissue location.

Abstract: A vaso-occlusive device includes a microcoil formed into a minimum energy state secondary configuration comprising a plurality of curved segments, each defining a discrete axis, whereby the device, in its minimum energy state configuration, defines multiple axes. In a preferred embodiment, the minimum energy state secondary configuration comprises a plurality of tangentially-interconnected, substantially circular loops defining a plurality of discrete axes. In an alternative embodiment, the minimum energy state secondary configuration defines a wave-form like structure comprising a longitudinal array of laterally-alternating open loops defining a plurality of separate axes. In either embodiment, the device, in its minimum energy state secondary configuration, has a dimension that is substantially larger than the largest dimension of the vascular site in which the device is to be deployed.

Abstract: Disclosed are occluders and methods of their use. The occluders comprise shape-memory polymeric materials which, when heated above their crystalline melting temperatures, may be deformed from a first configuration into a second configuration. The occluder is then held in the deformed shape until it cools to a temperature below its crystalline melting temperature (Tm) whereby it holds the deformed shape of the second configuration by virtue of the recrystallization of the polymeric occluder material. Upon reheating the occluder above its Tm, the occluder will resume its original shape. In this manner, an occluder which has been deformed to reduce its diameter may be inserted into and positioned within a target lumen in the body and then allowed to warm to body temperature whereby it resumes its original diameter and results in the occlusion of the lumen. The occluders, according to preferred embodiments, may be used for reversible sterilization of mammals, among other surgical and non-surgical uses.