Abstract: The present disclosure involves a method of setting stimulation parameters for neurostimulation. A plurality of stimulation parameters available for bracketing is displayed. The stimulation parameters are selected from the group consisting of: stimulation current amplitude, pulse width, frequency, and contact location. Thereafter, in response to an input from a user, at least a subset of the stimulation parameters is selected for bracketing. A respective initial value is then obtained for each of the stimulation parameters in the selected subset. Thereafter, a bracketing process is used to generate a plurality of bracketed values for each of the stimulation parameters in the selected subset. The bracketed values are generated as a function of the initial value. A plurality of stimulation pulses is then delivered to a patient through a neurostimulator that is automatically programmed with a different combination of the bracketed values for the stimulation parameters for each stimulation pulse.

Abstract: A stimulation device that stimulates living tissue includes an energy harvesting circuit that receives an output signal from another device and that powers the stimulation device, immediately or otherwise, using the output signal. The stimulation devices also includes a stimulation circuit that generates a stimulation signal to elicit a predetermined response from the living tissue, and at least one lead that delivers the stimulation signal to the living tissue.

Abstract: Methods and apparatus, including computer program products, are provided for remote monitoring. In some example implementations, there is provided a method. The method may include receiving, at a remote monitor, a notification message representative of an event detected, by a server, from analyte sensor data obtained from a receiver monitoring an analyte state of a host; presenting, at the remote monitor, the notification message to activate the remote monitor, wherein the remote monitor is configured by the server to receive the notification message to augment the receiver monitoring of the analyte state of the host; accessing, by the remote monitor, the server, in response to the presenting of the notification message; and receiving, in response to the accessing, information including at least the analyte sensor data. Related systems, methods, and articles of manufacture are also disclosed.

Abstract: Disclosed is a system and method of directing a biosignal detector arrangement. The system for directing a biosignal detector arrangement may include a biosignal detector configured to detect a biosignal of an object, a measurer configured to obtain, in real-time, information including surface data of the object and position data associated with an arrangement of the biosignal detector relative to the object based on the surface data, a processor configured to set initially obtained information of the obtained information as reference information for a surface registration and compare the reference information to finally obtained information of the obtained information, and a display configured to display the reference information and the finally obtained information.

Abstract: A biosensor having a hollow coil having wires coiled in parallel and an electronic circuit component operably connected to the coil, wherein the wires include at least a first coiled wire which may be used as a counter electrode, a second coiled wire which may be used as a working electrode and a third coiled wire which may be used as a reference electrode, wherein the second coiled wire is provided with a biocompatible layer having a bioreceptor, wherein the electronic circuit component is capable of generating an input signal for a transceiver based upon the activity of the bioreceptor and wirelessly sending the input signal to the transceiver, wherein the electronic circuit component is encapsulated in a biocompatible resin.

Abstract: A method, a computer readable media and a hand-held device, the hand-held device may include a first sensor that is positioned such as to be contacted by a first hand of a user when the user holds the hand-held device; a second sensor that is positioned such as to be contacted by a second hand of the user when the user holds the hand-held device; wherein at least one sensor of the first sensor and the second sensor is a hybrid sensor that comprises an electrode, an illumination element and a light detector; and a health monitoring module arranged to process detections signals from the electrode and from the light detector such as to provide processed signals that are indicative of a state of the user.

Abstract: There is provided a method involving a portable medical device (1), being carried by a user and a mobile phone (2) carried by the same user, the method comprising the steps of a) the mobile phone (2) at a time point (first time point) determining a geographical position of the mobile phone (2), and providing the geographical position and the first time point to a server (4) via a data connection, or the mobile phone (2) having its position determined by the cell network (3), and the cell network (3) providing the position and the first time point to the server (4), then b) the server (4) using the position and the time point to retrieve position-specific data for the time point, then c) the server (4) using a the data from step b. to determine whether the medical device should be serviced or replaced. There is also provided a system, a server and a mobile phone.

Abstract: A method of monitoring a patient includes measuring neural respiratory drive using a monitoring device (10), repeating the measurement either continuously or at regular time intervals, and comparing the measurements obtained in order to predict treatment failure and/clinical deterioration and/or re-admission. In embodiments of the invention, the neural respiratory drive is measured by obtaining a measure of the second intercostal space parasternal electromyogram. A monitoring device (10) includes a signal input (20), a processing unit (30), and a output unit (50), and is arranged to measure the neural respiratory drive, store the measured value and compare it to a previously measured value for the neural respiratory drive.

Abstract: Pacemaker heart diagnostics implantable cardiac stimulation method and device for pacemaker generated signal transmission and pacemaker signal reception. Processing and filtering a heart generated signal, in a pacemaker device, into a processed and filtered baseband signal. Heart generated signal is provided to pacemaker device by one or more electrodes; electrodes are connected or inserted into a heart. Providing processed and filtered baseband signal to a modulator for modulation and transmitter for transmission. Receiving in pacemaker device a modulated signal, demodulating received modulated signal into a filtered baseband signal and using this demodulated signal to control said pacemaker. The pacemaker communicates by one or more of Bluetooth or OFDM or CDMA signals.

Abstract: Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.

Abstract: A device, system and method for increasing air intake by a subject is described. The device includes a vibration motor and a control unit for controlling vibrational motion output by the vibration motor. The methods include positioning the vibration motor on one or more limbs of a subject, and stimulating nerves in the limbs via the generated vibrational motion, whereby the stimulated nerve signals the brain to increase breathing rate or air intake by the subject. Accordingly, embodiments of the device activate nerve fibers that carry kinesthetic cues from the limbs in a pattern that simulates normal limb motion, and thus triggers inherent reflexes that increase ventilation in response to such motion.

Abstract: The present development is a device for monitoring uterine activity and sending an alert signal through a wireless communication means when uterine activity significantly changes relative to a preset standard. The device, which comprises at least one sensor, is intended to continuously monitor a prescribed activity, such as uterine contractions. The information gathered by the sensors is fed to a computer application for comparison to preset values and, if the gathered information falls outside of the range of the preset values, feeds a signal to a second application designed to send out notifications to preprogrammed devices indicating the physical location of the source data, or where the pregnant patient is located.

Abstract: An occurrence of one or more “care events” is detected by an electronic device monitoring environmental data and/or user data from one or more sensors. The electronic device transmits one or more alerts regarding the detected occurrence to at least one other electronic device. In some cases, the electronic device may cooperate with at least one other electronic device in monitoring, detecting, and/or transmitting. For example, the electronic device may detect the occurrence based on sensor data received from a cooperative electronic device or such data in combination with the electronic device's sensor data. By way of another example, the electronic device may detect the occurrence and signal a cooperative electronic device to transmit one or more alerts.

Abstract: Provided is an authenticating apparatus that, in the case where authentication is performed repeatedly for the same operator, is capable of performing authentication without the operator having to consciously input unique information from the second time on. The weight scale measures the weight of an operator. The weight-registering unit, when an operator is authenticated as a user registered in an authentication list, registers the measured weight measured by the weight scale in the authentication list as a registered weight of the user. The user-selection-receiving unit receives a selection of a user. The weight-comparing unit authenticates an operator as a user registered in the authentication list by determining whether or not the registered weight of a user, of which a selection is received by the user-selection-receiving unit, is registered in the authentication list, and comparing the measured weight and the registered weight.

Abstract: Systems and methods for detecting and reporting patterns in analyte concentration data are provided. According to some implementations, an implantable device for continuous measurement of an analyte concentration is disclosed. The implantable device includes a sensor configured to generate a signal indicative of a concentration of an analyte in a host, a memory configured to store data corresponding at least one of the generated signal and user information, a processor configured to receive data from at least one of the memory and the sensor, wherein the processor is configured to generate pattern data based on the received information, and an output module configured to output the generated pattern data. The pattern data can be based on detecting frequency and severity of analyte data in clinically risky ranges.

Abstract: Methods, sensors, and systems that prevent or reduce data loss when more than one external sensor transceiver is used with a sensor. A sensor may receive a transceiver identification (ID) of an external transceiver conveyed from the external transceiver and determine whether the received transceiver ID is a new transceiver ID. If sensor determines the received transceiver ID to be a new transceiver ID, the sensor may store the received transceiver ID in a nonvolatile storage medium of the sensor and convey, using the sensor, measurement information stored in the nonvolatile storage medium to the external transceiver.

Abstract: Various embodiments of a power source and a method of forming such power source are disclosed. The power source can include an enclosure, a substrate disposed within the enclosure, and radioactive material disposed within the substrate and adapted to emit radioactive particles. The power source can further include a diffusion barrier disposed over an outer surface of the substrate, and a carrier material disposed within the enclosure, where the carrier material includes an oxide material.

Abstract: A medical system and method of communicating between a telemetry controller and a plurality of medical devices implanted within a patient is provided. Communication links are respectively established between the telemetry controller and the implanted medical devices. The communication links are respectively amplitude modulated by the implanted medical devices at modulation levels using load modulation. Received signal strength indicators (RSSIs) of the amplitude modulated communication links for the implanted medical devices are measured. A variation of the RSSIs is decreased by modifying, based on the measured RSSIs, at least one modulation level at which the respective at least one communication link is amplitude modulated by the respective implanted medical device(s).

Abstract: Systems and methods are provided for managing patient activated capture of transient data by an implantable medical device (IMD). The systems and methods collect transient data using the IMD. The collected transient data is stored in a temporary memory section of the IMD. The IMD receives a patient activated storage request including activation information related to a patient designated trigger point from an external device. The IMD transfers a segment of the transient data from the temporary memory section to a long-term memory, wherein the segment of transferred transient data is based on the trigger point. The activation information includes an elapsed time corresponding to a duration of time between entry of the trigger point and issuance of the patient activated storage request by an external activation device.

Abstract: An implantable medical device comprises a communication module that comprises at least one of a receiver module and a transmitter module. The receiver module is configured to both receive from an antenna and demodulate an RF telemetry signal, and receive from a plurality of electrodes and demodulate a tissue conduction communication (TCC) signal. The transmitter module is configured to modulate and transmit both an RF telemetry signal via the antenna and a TCC signal via the plurality of electrodes. The RF telemetry signal and the TCC signal are both within a predetermined band for RF telemetry communication. In some examples, the IMD comprises a switching module configured to selectively couple one of the plurality of electrodes and the antenna to the receiver module or transmitter module.

Abstract: A wearable computer is used for monitoring process data in road finishing. The wearable computer receives process data of the road finishing process. In the event of process data lying outside a predetermined range, the wearable computer effects alerting of the wearer of the wearable computer.

Abstract: A horn and an anvil are moved toward and away from each other by axially reciprocating a driving rod and thereby reciprocatingly rotating a forked lever in a predetermined angle range. The horn and the anvil are moved toward and pressed against each other with a predetermined force with a bag mouth b held therebetween. A sensor detects the position of a second mounting block secured to the rear end of a sliding shaft of the anvil, thereby detecting the distance between respective pressing surfaces of the horn and the anvil, i.e. the thickness m of a portion of the bag mouth held between the pressing surfaces. When the thickness m is not less than a predetermined threshold value M, a vibrator is activated to perform sealing. When the thickness m is less than the threshold value M, no sealing is performed.

Abstract: A sensing device includes a printed circuit board (PCB) having a conductive trace. A micro-controller is attached to the conductive trace and data transmission means is connected to the micro-controller. A sensor is embedded within the PCB and is connected to the micro-controller via the conductive trace. The sensor is configured to sense at least one physiological parameter in a patient.

Abstract: A network communications component may be configured to self-lock at a signaled transmission rate. The network communications component may receive a first transmission rate signal indicating a first transmission rate. It may be determined that a transmission rate for the network communications component is unset on the network communications component. Determining that the transmission rate for the network communications component is unset may include accessing an entry for the transmission rate in a vital product data stored on the network communications component. The transmission rate for the network communications component may be set by storing an indication of the received first transmission rate in a memory location on the network communications component. Data transmission by the network communications component may be limited, in accordance with the stored indication of the first transmission rate, to not exceed the set transmission rate.

Abstract: An implantable electrode array is provided that includes a carrier that is flexible. At least one control module is coupled to the carrier. A shell encases the control module. At least one electrode is coupled to the carrier and is electrically connected to the control module.

Abstract: An apparatus, such as a pressure support ventilator or respiratory monitor, provides operations for a patient, such as a patient with heart failure, Chronic Obstructive Pulmonary Disease or other respiratory insufficiency. In some embodiments, the apparatus may detect a respiratory condition, such as a decompensation event and/or exacerbation event, from respiratory parameters. A clinical alert message may be transmitted or displayed for a physician based on the results of query presented to the patient in response to an analysis of the one or more respiratory parameters. In some embodiments, the apparatus generates a potential relapse indicator that may provide a prediction of a risk of an oncoming clinical event such as for evaluating whether to release the patient from a hospital.

Abstract: The disclosure describes a flexible-rigid hybrid design for an endoscope and attachment mechanisms for removably coupling and decoupling the endoscope to a handle portion and/or a tool portion of a variety of different instruments. Some implementations describe designs for instruments that may be coupled to the flexible-rigid endoscope described herein or other endoscopes. Such instruments may include sinus and laryngeal forceps, a laryngeal syringe gun, an endoscopic Eustachian tube balloon dilator, an endoscopic tracheal dilator, and an endoscopic trans-oral esophageal balloon dilator. Some implementations describe an endoscope that may be removably coupled to a portable control box using a connector cable.

Abstract: A medical device control unit is provided. The control unit may include a communications interface, a memory, and at least one processing device. The processing device may be configured to cause application of a control signal to a primary antenna associated with a unit external to a subject's body. The processing device may further be configured to monitor a feedback signal indicative of the subject's breathing and store, in the memory, information associated with the feedback signal. The processing device may also cause transmission of the stored information, via the communications interface, to a location remote from the control unit. The processing device may further be configured to receive an update signal, from the location remote from the control unit, and cause application of an updated control signal to the primary antenna based on the update signal.

Abstract: Methods and devices to monitor an analyte in body fluid are provided. Embodiments include continuous or discrete acquisition of analyte related data from a transcutaneously positioned in vivo analyte sensor automatically or upon request from a user.

Abstract: A cardiac monitoring and treatment system includes a wearable defibrillator worn about the torso of a patient and a remote device configured to communicate with the wearable defibrillator. The wearable defibrillator includes one or more buttons configured to be actuated by the patient to cause the wearable defibrillator to withhold an imminent delivery of a therapy necessitated by a detected cardiac arrhythmia. The remote device includes a touch screen including one or more remote response buttons accessible by the patient to respond to a notification of the imminent delivery of the therapy necessitated by the detected cardiac arrhythmia. Actuation of either the one or more remote response buttons of the remote device or the one or more buttons of the wearable defibrillator causes the wearable defibrillator to withhold the imminent delivery of the therapy necessitated by the detected cardiac arrhythmia.

Abstract: An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor has, for example, a substrate, a recessed channel formed in the substrate, and conductive material disposed in the recessed channel to form a working electrode. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte.

Abstract: A leadless cardiac pacemaker (LCP) configured to sense cardiac activity and to pace a patient's heart. The LCP may include a housing, a first electrode secured relative to the housing, a second electrode secured relative to the housing, and a pressure sensor secured relative to the housing and coupled to the environment outside of the housing. The LCP may further include circuitry in the housing in communication with the first electrode, the second electrode, and the pressure sensor. The circuitry may be configured to determine and store a plurality of impedance-pressure data pairs, from which a representation of a pressure-volume loop may be determined.

Abstract: A server system for remote monitoring includes a wireless communication interface, a processor, and a storage device. The wireless communication interface receives at least one data packet over wireless communications from a remote monitoring system. The processor processes the data packet including sensor information from a sensor coupled to the remote monitoring system. The storage device stores the sensor information.

Abstract: A server system for remote monitoring includes a wireless communication interface, a processor, and a storage device. The wireless communication interface receives at least one data packet over wireless communications from a remote monitoring system. The processor processes the data packet including sensor information from a sensor coupled to the remote monitoring system. The storage device stores the sensor information.

Abstract: There is provided a monolithically integrated multimodal sensor device for intracranial neuromonitoring, the sensor device including: a single substrate; a temperature sensor formed on a first portion of the single substrate for detecting temperature; a pressure sensor formed on a second portion of the single substrate for detecting intracranial pressure; and an oxygen sensor formed on a third portion of the single substrate for detecting oxygen concentration. In particular, sensing portions of the temperature sensor, the oxygen sensor and the pressure sensor, respectively, are formed at different layers of the sensor device. There is also provided an integrated multimodal sensor system incorporating the sensor device and the associated methods of fabrication.

Abstract: A passive implantable relay module includes a first coupler arm configured to wirelessly receive electromagnetic energy radiated through electric radiative coupling from a transmitting antenna located outside a subject's body; a second coupler arm; and a connector portion comprising a first metal core and a first dielectric coating surrounding the first metal core, the connector portion configured to connect the first coupler arm to the second coupler arm such that when the passive implantable relay module is implanted inside the subject's body and the transmitting antenna initiates wireless energy transfer to the first coupler arm via non-inductive coupling, electromagnetic waves carrying the electromagnetic energy received at the first coupler arm propagate along the first metal core to arrive at the second coupler arm, where the electromagnetic energy arriving is wirelessly transferred, again via non-inductive coupling, to a receiving antenna on a passive wireless neural stimulator device.

Abstract: Ingestible event marker systems that include an ingestible event marker (i.e., an IEM) and a personal signal receiver are provided. Embodiments of the IEM include an identifier, which may or may not be present in a physiologically acceptable carrier. The identifier is characterized by being activated upon contact with a target internal physiological site of a body, such as digestive tract internal target site. The personal signal receiver is configured to be associated with a physiological location, e.g., inside of or on the body, and to receive a signal the IEM. During use, the IEM broadcasts a signal which is received by the personal signal receiver.

Abstract: The methods, systems, and devices disclosed herein generally involve convection-enhanced delivery of drugs to a target region within a patient. Microfluidic catheter devices are disclosed that are particularly suitable for targeted delivery of drugs via convection, including devices capable of multi-directional drug delivery, devices that control fluid pressure and velocity using the venturi effect, and devices that include conformable balloons. Methods of treating various diseases using such devices are also disclosed, including methods of treating cerebral and spinal cavernous malformations, cavernomas, and hemangiomas, methods of treating neurological diseases, methods of treatment using multiple microfluidic delivery devices, methods of treating hearing disorders, methods of spinal drug delivery using microfluidic devices, and methods of delivering stem cells and therapeutics during fetal surgery. Methods of manufacturing such devices are also disclosed.

Abstract: A blood pump control system includes a local processing terminal and a remote processing terminal. The local processing terminal is configured to transmit to the remote processing terminal, collected current state parameters of the blood pump and heart activity indexes, and to drive and control the blood pump according to blood pump adjusting parameters received from the remote processing terminal. The remote processing terminal is configured to obtain current blood pump adjusting parameters according to the current state parameters, and the heart activity indexes received from the local processing terminal, and set adjusting conditions; and to transmit the blood pump adjusting parameters back to the local processing terminal.

Abstract: Disclosed is a cardio-pulmonary health monitoring apparatus. The apparatus comprises a contactless motion sensor configured to generate one or more movement signals representing bodily movement of a patient during a monitoring session; a processor; and a memory storing program instructions configured to cause the processor to carry out a method of processing the one or more movement signals. The method comprises extracting one or more sleep disordered breathing features from the one or more movement signals, and predicting whether a clinical event is likely to occur during a predetermined prediction horizon based on the one or more sleep disordered breathing features.

Abstract: Repeaters are described that operate to rapidly transition from low-power standby states to a low frequency signal transmission state. Bandwidth for high-frequency signal transmission is preserved.

Abstract: In one embodiment, a method is disclosed in which an analog sensor receives an electromagnetic (EM) wave (e.g., a radio frequency signal) from an interrogation device. The sensor converts a biological measurement of a subject into an electrical resistance and modulates a response to reflect the incident signal based on the electrical resistance. The sensor then provides the response to the interrogation device that corresponds to the biological measurement.

Abstract: Disclosed are systems and methods for use of an inductive link for a communication channel in a transcutaneous energy transfer system.

Abstract: A method, computer program product, and infusion pump assembly for administering a sequential, multi-part, infusion event, wherein the sequential, multi-part, infusion event includes a plurality of discrete infusion events. If a one-time infusion event is available to be administered, the administration of at least a portion of the plurality of discrete infusion events included within the sequential, multi-part, infusion event is delayed. The one-time infusion event is administered.

Abstract: An alarm, locating and tracking apparatus is provided for the prevention a dependent from being lost from a caregiver. A transmitter that carried by each are programmed with a safe distance demarcation such that when a dependent travels past such a distance, an audible alarm sounds on both transmitters. This alarm is intended to prevent the dependent from becoming lost. Should the alarm fail to prevent such an incident, a location signal is transmitted to a local cellular telephone towers or by low earth orbiting satellites used for low power communication. When an adult or child is lost or in danger, the transmitter which sends a signal to a central reporting station or stations to provide location information to aid in the caregiver's search. The instant abstract is neither intended to define the invention disclosed in this specification nor intended to limit the scope of the invention in any way.

Abstract: Cardiac electrograms are recorded in a plurality of channels. Beats are classified automatically into respective classifications according to a resemblance of the morphologic characteristics of the beats to members of a set of templates. Respective electroanatomic maps of the heart are generated from the classified beats.

Abstract: Systems, devices disclosed provide example methods comprising determining that a triggering event has occurred based on statuses for a set of physiological parameters associated with the patient, the physiological parameters indicative of the patient engaging in a patient initiated physical activity, generating a trigger output signal in response to the determination that the triggering event has occurred, wirelessly transmitting the trigger output signal to a pressure sensing device implanted in a vessel of the patient, triggering, based on receiving the trigger output signal, the pressure sensing device to sense a cardiovascular pressure of the patient; and transmitting, by the pressure sensing device, a wireless signal comprising data corresponding to the sensed cardiovascular pressure of the patient.

Abstract: Disclosed are systems and methods for measuring and calculating parameters to control and monitor a power transfer in an implanted medical device, including operating the device in a plurality of scalable power modes and/or coupling modes. The system may shift between or among power and/or coupling modes based on input such as data received over system communication lines, programmable timers, or electrical loading information. The system may also shift between or among power and/or coupling modes based on calculated amounts of coupling, levels of detected heat flux, and/or amounts of estimated temperature changes.

Abstract: An inserter assembly for continuous glucose monitoring with medication delivery capability where the assembly has a deployment button containing a needle deployment mechanism having a sharp held in a pre-release position, a housing body in which the deployment button is movably received within a top end of the housing body, the housing body having a sensor deployment assembly containing a lumen and a sensor disposed within the lumen and extending out of the lumen to a circuit board that is part of the sensor deployment assembly, the sensor deployment assembly matingly connected to the sharp where the sharp extends beyond the sensor deployment assembly and contains the sensor not fixedly attached to the sharp, and a sensor housing releasably received within a lower end of the housing body, the sharp extending into a sensor deployment assembly recess within the sensor housing and directly above a sensor opening in a bottom of the sensor housing.

Abstract: A method is described and in one embodiment includes detecting a transition of a data signal comprising a data packet received at a circuit while the circuit is in a first hysteresis mode; placing the circuit in a second hysteresis mode subsequent to the detecting; and returning the receiver to the first hysteresis mode subsequent to completion of receipt of the data packet to await receipt of a next data packet. In certain embodiments, the first hysteresis mode is a high hysteresis mode and the second hysteresis mode is a standard hysteresis mode. In some embodiments, a level of each of the first and second hysteresis modes is dynamically tunable.