Abstract: An apparatus, system, and method for the regeneration of tissue by pre-tensioning of tissue prior to or in conjunction with the application of mechanotransduction therapy.

Abstract: A method for determining a lowest stimulation threshold current level in a group of channels of a neuromonitoring device. The method includes stimulating tissue at a current level from a predetermined range of current levels as a sequence of pulses delivered at a frequency. The stimulating includes increasing the current level of each pulse in the sequence of pulses from an immediately preceding pulse by a first current increment. The method includes determining that a first evocation pulse from the sequence of pulses evokes a first muscular response. The method includes stimulating the tissue with a second evocation pulse from the sequence of pulses to evoke a second muscular response. The stimulating includes decreasing the frequency of the delivery of each pulse in the sequence of pulses and increasing the current level of each pulse in the sequence of pulses from the immediately preceding pulse by a second current increment.

Abstract: A handheld device for sonifying electrical signals obtained from a subject is provided. The device can utilize at least one of several operations including (but not limited) digitizing signals from electrodes, adjusting the signals based on accelerometer input, filtering the signals, conditioning the signals according to conditioning parameters, modulating the signal according to sound synthesis parameters, and generating sound from the representations of the signals to accomplish sonification. The device can include an analog-to-digital (A/D) converter to digitize the one or more electrical signals and a processor that receives the one or more digitized electrical signals and produces a representation of an acoustic signal. The device further includes a speaker system that sonifies the representation of the acoustic signal.

Abstract: In a physiological sensor that estimates a true parameter value by providing a predicted parameter value, multiple measurements are taken to increase the accuracy of the predicted parameter value. The sensor can be reapplied between measurements to decrease the probability of an erroneous prediction caused by sensor misplacement. Some measurements can be discarded before calculating a predicted parameter value. The physiological sensor can have a plurality of modes, with one of the modes corresponding to multiple measurement process.

Abstract: A system for detecting and affecting the physiological condition of a user can include at least one non-contact sensor configured to detect at least one physiological condition of a user, and a device configured for affecting the user's environment. A controller can be configured to control operation of the device in response to signals from the sensor. The device can include a housing having an interior space, at least one light source positioned in the interior space, a window mounted to the housing and configured to allow light from the at least one light source to pass through the window and outwardly from the housing. Light can be emitted from the at least one light source so that brightness of the light changes through a time cycle that is serially repeated for guiding breathing of the user. The device can be independent of the system.

Abstract: A computer-implemented method for delivering therapy to a user includes: providing data representative of an initial sensory stimulus to a sensory stimulus device and causing the sensory stimulus device to provide the initial sensory stimulus to the user; receiving alpha wave biometric data of the user from a brain electrical activity sensor while the sensory stimulus device provides the initial sensory stimulus; determining whether the alpha wave biometric data meets sensory stimulus adjustment criteria; if the alpha wave biometric data meets sensory stimulus adjustment criteria, adjusting the sensory stimulus provided to the user by providing data representative of an adjusted sensory stimulus to the sensory stimulus device and causing the sensory stimulus device to provide the adjusted sensory stimulus; and if the alpha wave biometric data fails to meet sensory stimulus adjustment criteria, continue causing the sensory stimulus device to provide the initial sensory stimulus to the user.

Abstract: Disclosed is a method and a system implementing the method for determining an optimal time window for sleep of a person. The method includes receiving samples of a distal skin temperature of the person, and detecting a temperature change pattern in the samples of distal skin temperature. The temperature change pattern indicates a reference point within the circadian rhythm. The optimal time window for sleep is determined on the basis of the indicated reference point. The temperature change pattern is in the form of a drop in the distal skin temperature followed an increase in the distal skin temperature, where the drop and the increase occur within a time window of ten minutes or less.

Abstract: Systems and methods are provided that provide respiration entrainment cues to a user to encourage relaxation or a sleep state. The entrainment cues may be audible, visible, or tactile (or any combination). The entrainment cues include a rhythmic component associated with a target respiration rate and may include sub-components associated with a target breath architecture, such as an inhale-exhale cycle. The systems and methods detect the user's respiration to determine whether the user's respiration matches the entrainment cues or whether the user has fallen asleep.

Abstract: Proprioceptive feedback is provided in a residual limb of a person that includes forming a linkage between a pair of agonist and antagonist muscles, forming a sliding surface over which the agonist and antagonist muscles slide. The sliding surface can include a synovial sleeve, a bridge formed between the distal ends of bones, or a fixture that is osseointegrated into the bone. The invention also includes a system for transdermal electrical communication in a person that includes a percutaneous access device, a sensory device that communicates signals between a muscle and the percutaneous device, and a stimulation device in communication with the percutaneous access device. In another embodiment, a closed-loop functional stimulation system restores lost functionality to a person that suffers from impairment of a neurological control system or at least partial loss of a limb.

Abstract: An apparatus comprising: at least one processor; and at least one memory including computer program code, the at least one memory and the computer program code configured to, with the at least one processor, cause the apparatus to perform at least the following: receive respective sleep profiles of a plurality of users, each sleep profile comprising recorded sleep phases of a sleep session of a respective user of the plurality of users, receive a target sleep outcome of the plurality of users; and based on the respective sleep profiles and the target sleep outcome, determine one or more respective sleep adjustments for provision to at least one of the respective plurality of users, the respective sleep adjustments comprising stimuli configured to attempt to adjust a respective user's sleep during one or more of the respective user's sleep session and a subsequent sleep session, in an attempt to achieve, at least in part, the target sleep outcome of the plurality of users.

Abstract: The Plant Choir™ system comprises a software program and hardware that measures the electrodermal activity of a person, plant, or animal and translates those readings into music on a computing device. The EDA readings of the individual subjects are translated via the software into musical notes in real time. The creation of the notes is synchronized to a master tempo in order to allow the subjects to play together in a unified fashion similar to a choir. A riff mode allows the subjects to produce multiple notes per beat. The music is rendered using a software synthesis algorithm that employs the pre-recorded sounds of real instruments. The software can also utilize MIDI devices if the operating system has that capability. The software allows the user to load and save their settings so they can create and experiment with their own choir configurations and musical scales.

Abstract: The present disclosure pertains to a system configured to facilitate prediction of a sleep stage and intervention preparation in advance of the sleep stage's occurrence. The system comprises sensors configured to be placed on a subject and to generate output signals conveying information related to brain activity of the subject; and processors configured to: determine a sample representing the output signals with respect to a first time period of a sleep session; provide the sample to a prediction model at a first time of the sleep session to predict a sleep stage of the subject occurring around a second time; determine intervention information based on the prediction of the sleep stage, the intervention information indicating one or more stimulator parameters related to periheral stimulation; and cause one or more stimulators to provide the intervention to the subject around the second time of the sleep session.

Abstract: Systems and methods for monitoring an individual's condition based on model generated from e-textile based clothing are described. A computer-implemented a method includes: obtaining, by a computer device, sensor data from an e-textile garment worn by a user; generating, by the computer device, a wireframe model of the user based on the sensor data; determining, by the computer device, a user activity; determining, by the computer device, a user condition based on the user activity and a the wireframe model; and automatically contacting, by the computer device, an assistance provider system based on determining the user condition warrants assistance.

Abstract: A method is provided of systematically evaluating and treating dynamic autonomic dysregulation in a subject. The method includes having the subject sequentially assume a plurality of distinct postures that may include, for example, walking, standing, sitting or supine. In each posture of the subject, the subject is subjected to sensory stimulation while measuring at least one autonomic physiological response of the subject. The autonomic physiological response may include, for example, oxygen saturation, heart rate, pupillary response, blood pressure, sweat production, pseudomotor activity or respiration. The physiological responses in each of the distinct postures are evaluated to identify a posture wherein the subject exhibits a least amount of dysfunction.

Abstract: A system performs surgical procedures and assessments. The system includes the use of neurophysiology-based monitoring to determine nerve proximity and nerve direction to surgical instruments employed in accessing a surgical target site.

Abstract: A baby monitor system comprises: a memory; and a processor coupled to the memory and configured to: obtain a sleep schedule of a baby; obtain vitals of the baby, wherein the vitals are based on pulse oximetry; and cause a first sound or a first light to emit in response to the sleep schedule and the vitals. A method comprises: obtaining a sleep schedule of a baby; obtaining vitals of the baby, wherein the vitals are based on pulse oximetry; and causing a first sound or a first light to emit in response to the sleep schedule and the vitals.

Abstract: Systems and methods to mitigate negative effects of a drug in a treatment of a mental health condition include administering a drug to a subject in a therapy session; determining effects of the drug, the effects being counterproductive to the therapy session; and providing tactile stimulation to a subject with a stimulation device that generates transcutaneous vibratory output to be applied to a portion of a body of the subject during the therapy session, wherein the transcutaneous vibratory output is selected to reduce the counterproductive effects of the drug.

Abstract: A sleep sensing system comprising a sensor to obtain real-time information about a user, a sleep state logic to determine the user's current sleep state based on the real-time information. The system further comprising a sleep stage selector to select an optimal next sleep state for the user, and a sound output system to output sounds to guide the user from the current sleep state to the optimal next sleep state.

Abstract: A method for producing and streaming music generated from plants. Plant microfluctuations are converted to MIDI notes and subsequent CC messages, and are mapped to a unique signal chain of virtual instruments and effects to produce musical notes which are output through the speakers of an apparatus, or through a linked portable electronic device.

Abstract: A method is provided of systematically evaluating and treating dynamic autonomic dysregulation in a subject. The method includes having the subject sequentially assume a plurality of distinct postures that may include, for example, walking, standing, sitting or supine. In each posture of the subject, the subject is subjected to sensory stimulation while measuring at least one autonomic physiological response of the subject. The autonomic physiological response may include, for example, oxygen saturation, heart rate, pupillary response, blood pressure, sweat production, pseudomotor activity or respiration. The physiological responses in each of the distinct postures are evaluated to identify a posture wherein the subject exhibits a least amount of dysfunction.

Abstract: A method for gaming. The method includes assigning a default game play profile to a user, wherein the default game play profile includes a default game play style that simulates human game play, and wherein the default game play profile is configured to control game play for the user based on the default game play style. The method includes monitoring a plurality of game plays of the user playing a plurality of gaming applications. The method includes generating a user game play profile of the user by adjusting the default game play style based on the plurality of game plays, wherein the user game play profile includes a user game play style customized to the user. The method includes controlling an instance of a first gaming application based on the user game play style of the user game play profile.

Abstract: An audio signal generation device (20) includes: an acquirer (210) configured to acquire biological information of a human subject; an audio signal generator (245) configured to generate an audio signal based on at least one of a plurality of pieces of sound information; and a switching cycle decider (241) configured to decide a switching cycle, such that first sound information switches to second sound information at a cycle that is in accordance with the biological information, the first sound information and the second sound information being included in the plurality of sound information pieces, and the audio signal generator (245) generates an audio signal based on the second sound information, at the switching cycle decided by the switching cycle decider (241).

Abstract: A system includes at least one wearable device having a housing, at least one sensor disposed within the housing, at least one output device disposed within the housing, and at least one processor operatively connected to the sensors and output devices, wherein one or more sensors are configured to detect electrical activity from a user's facial muscles and to transmit a data signal concerning the electrical activity of the user's facial muscles to one of more of the processors. A method of controlling a wearable device includes determining facial muscular electrical data of a facial gesture made by a user, interpreting the facial muscular electrical data to determine a user response, and performing an action based on the user response.

Abstract: For automatic operation of an ergonomic equipment according to dynamic workplace conditions, an activity being performed in a workplace by a person at a first time is determined based on an input from a data processing system. A group is selected corresponding to the activity. An ergonomic policy is modified to form a modified ergonomic policy. The ergonomic policy applies to the activity, and the modification is based on a condition existing in the workplace at the first time of the person performing the activity. Independent of a participation of the person, and when the person is not in compliance with the modified ergonomic policy, an ergonomic control is activated. The ergonomic control causes a change in an ergonomic feature of the ergonomic equipment, the change causing the person to become compliant with the modified ergonomic policy.

Abstract: For automatic operation of an ergonomic equipment according to dynamic workplace conditions, an activity being performed in a workplace by a person at a first time is determined based on an input from a data processing system. A group is selected corresponding to the activity. An ergonomic policy is modified to form a modified ergonomic policy. The ergonomic policy applies to the activity, and the modification is based on a condition existing in the workplace at the first time of the person performing the activity. Independent of a participation of the person, and when the person is not in compliance with the modified ergonomic policy, an ergonomic control is activated. The ergonomic control causes a change in an ergonomic feature of the ergonomic equipment, the change causing the person to become compliant with the modified ergonomic policy.

Abstract: System and methods for detecting precursors of VAP in a patient being ventilated. An exemplary method comprises obtaining a baseline value for a content of a particular VOC in tVOCs in exhaled breath of the patient being ventilated, trending changes of values of the content of the particular VOC in the tVOCs measured at various points of time after ventilation compared to the baseline value, determining whether the patient has potentially infected VAP based at least in part on the trending, and in response to determining that the patient has potentially infected the VAP, generating an alert.

Abstract: Provided are mechanisms and processes for more effectively monitoring infants to enhance caregiving and infant development. A system may include a wearable infant monitoring device, transmission interface, and monitoring hub. The wearable infant monitoring device includes sensors that detect activity and position of an infant. The transmission interface transmits measurement data associated with the activity and position of the infant. The monitoring hub receives the measurement data and includes a processor configured to determine the infant's receptivity to learning. Learning materials are then provided to a caregiver through a display interface based on the infant's receptivity to learning.

Abstract: The present disclosure relates generally to systems and methods that enable access control for digital objects based on measured physiological signals of a user. A method of operation of a human mind interface (HMI) system includes measuring, via a physiological sensor of a HMI device, a brain pattern of a user while the user retrieves a digital object after training. The method includes identifying, via a processor of the HMI device, the measured brain pattern stored in a memory of the HMI device, and determining, via the processor, the digital object stored in the memory that is associated with the identified brain pattern. The method includes accessing, via the processor, the digital object and retrieving information contained in the digital object and providing, via the processor of the HMI device, the information contained in the digital object to a recipient on behalf of the user.

Abstract: An air mattress adjustment method includes adjusting the air mattress to a received user pressure setting, learning a level of pressure in the air mattress at a first plurality of times with respect to the user pressure setting, monitoring the level of pressure in the air mattress at a second plurality of times, determining that the pressure of the air mattress at one of the second plurality of times is out of range, and based on the determining, adjusting the pressure of the air mattress.

Abstract: A method for producing and streaming music generated from biofeedback. The method employs machine-readable language instructions that alter received signals from a wearable biofeedback device, generating musical tones to be played on a portable electronic device and/or shared with others. The varying musical tones that are produced by the method can be modulated by the user to reach a targeted state of emotion.

Abstract: Devices, methods, systems, and computer program products for quantifying the amount of pressure exerted on a tooth or a set of teeth by an aligner. The quantification may be facilitated by a sensor disposed in the aligner and the sensor may be configured to generate an output signal signifying the amount of pressure in response to receiving an input signal. The input signal may be generated by a detection instrument or a computing device. The amount of pressure may be stored in a treatment tracking software and/or treatment tracking database for review and consideration by a treatment professional. The treatment professional may thereafter make decisions about the orthodontic treatment based on quantified amount of pressure on the tooth or set of teeth.

Abstract: A computerized method for an electronic game includes starting a round of play of the electronic game, and during the round of play monitoring a physiological attribute of a user's body. The method includes determining whether a value of the physical attribute exceeds a threshold level, and changing a chance of winning the round of play if the value of the physical attribute exceeds the threshold level. Changing a chance of winning the round of play may include increasing the chance of winning the round of play from a first chance to a higher second chance, where the round of play is for a game of chance.

Abstract: A living area includes a lying and eating area and a milking area. The living area is connected to a separation area by a selection device. A subgroup of dairy animals to be separated is determined together with a desired end time at which the dairy animals to be separated should be present in the separation area. For each individual dairy animal from the subgroup to be separated, an individual separation period is determined separately which runs from the individually determined start time until the end time. A dairy animal which walks to the selection device is guided by the selection device to the separation area if the dairy animal belongs to the subgroup of dairy animals to be separated and if said dairy animal is present at the selection device during the individual separation period determined for said dairy animal. The activity of each dairy animal in the group of dairy animals is observed by an observation system while the dairy animal is in the lying and eating area.

Abstract: A brainwave actuated apparatus has a brainwave sensor for outputting a brainwave signal, an effector responsive to an input signal, and a controller operatively connected to an output of said brainwave sensor and a control input to said effector. The controller is adapted to determine characteristics of a brainwave signal output by said brainwave sensor and based on said characteristics, derive a control signal to output to said effector.

Abstract: An ECT system capable of focusing the electrical signals on a specific portion of the patient's brain is provided. The ECT system includes a means of applying unidirectional electrical signals and asymmetric electrodes for focusing the signals on the patient. A method of titrating an electro-convulsive therapy (ECT) system and a method of operating an ECT system are also provided. The method includes setting an initial current value, administering an ECT signal to the patient, determining if the seizure threshold has been achieved, and repeating as necessary until the seizure threshold is achieved.

Abstract: Apparatus (20) for use with a subject (30) is provided, including a memory, storing a set of computer instructions, the memory adapted to have stored therein an initial form of a multi-phase biorhythmic activity pattern and an indication of a desired form of the multi-phase biorhythmic activity pattern, wherein a ratio of durations of two phases in the desired form is different from a ratio of durations of the respective phases in the initial form, and wherein at least one phase of the multi-phase biorhythmic activity pattern corresponds to a respective phase of a multi-phase biorhythmic activity of the subject (30).

Abstract: A wearable robot may include a gear part having an exoskeleton structure to be worn on legs of a user, a sensor part including a first electromyogram (EMG) sensor attached at a first location of at least one leg of the user, and a second EMG sensor attached at a second location, and a controller to detect a walking assist starting point to assist the user with walking, based on a first EMG signal detected by the first EMG sensor and a second EMG signal detected by the second EMG sensor.

Abstract: The present disclosure pertains to a system configured to manage a sleep session of a subject. In some embodiments, the sleep session is a nap and the system is configured to increase the restorative value of the nap by enhancing and/or maintaining sleep slow waves (and/or slow wave activity estimated using an EEG) in the subject during the nap with sensory stimuli. The present system is configured to enhance restorative sleep during a nap by delivering sensory stimulation to the subject during lighter NREM sleep stages (e.g., during a portion of stage N2 sleep) while still avoiding arousals. In some embodiments, the system is configured to facilitate a “powernap” by delivering the sensory stimulation to the subject in such a way so as to prevent transition into deep sleep (e.g., stage N3 sleep).

Abstract: Apparatus is provided, including a sensor, adapted to generate a sensor signal indicative of biorhythmic activity of a user of the apparatus, the sensor signal having a first characteristic, indicative of a voluntary action of the user, and a second characteristic, indicative of a benefit-related variable of the user. The apparatus also includes a control unit, adapted to receive the sensor signal, and, responsive to the second characteristics generate an output signal which directs the user to modify a parameter of the voluntary action indicated by the first characteristic.

Abstract: Introduced here are techniques for developing personalized retroactive insights into how contextual factors can affect glycemic responses. The personalized retroactive insights can be made available to the corresponding individual so that they can examine the impact certain contextual events have had on blood glucose level. A contextual event represents an activity or a circumstance that is related to glycemic response. Rather than state the absolute amount of certain molecules (e.g., carbohydrates, protein, or fat) in a foodstuff, an insight detection platform can instead interpret disparate data types to discover the effect certain contextual events have on blood glucose level.

Abstract: The present disclosure pertains to a system that facilitates transitions between sleep states and/or stages during a sleep session of a subject. The system facilitates transitions between sleep states and/or stages by monitoring the brain activity of a subject and providing sensory stimulation to guide brain activity parameters into target ranges. The system includes one or more of a sensory stimulator, a sensor, a processor, electronic storage, a user interface, and/or other components.

Abstract: A system employs data taken from monitor devices and applies that data to video games, arcade games, computer games and the like (collectively a “game”) to “personalize” the game to real ability and persons. For example, when a monitor device is used to capture airtime (and e.g., heart rate) of a snowboarder, that data is downloaded to a database for a game and used to “limit” how a game competitor plays the game. In this way, a snowboard game player can compete against world-class athletes, and others, with some level of realism provided by the real data used in the game.

Abstract: Disclosed are systems and methods to provide a patient care recommendation. The systems and methods receive patient information and a plurality of patient physiological signals that are related to a patient. The systems and methods are then operable to produce at least one derived patient signal from at least one of the plurality of patient physiological signals. The systems and methods use the patient information, at least one of the plurality of patient physiological signals, and the at least one derived patient signal to provide at least one patient care recommendation.

Abstract: The present disclosure discloses an arrangement for measuring a biosignal. The arrangement has a sensor module and a control module. The sensor module has structure for sensing at least one biosignal and a first connector for interfacing with the control module. The control module has a first counterpart connector connected to the first connector of the sensor module, structure for processing biosignal data sensed with the sensor module, a storage memory for storing processed bio signal data, a rechargeable battery for providing operating power for the control module, structure for wirelessly transmitting the processed biosignal data to a computing device, such as a PC, a tablet PC or a smart phone, for post-processing, and a second connector for interfacing with a second electrode.

Abstract: The present disclosure relates to methods, devices and systems used for the treatment of mood, anxiety, post traumatic stress disorder, and cognitive and behavioral disorders (collectively, neuropsychiatric disorders) via stimulation of the superficial elements of the trigeminal nerve (“TNS”). More specifically, cutaneous methods of stimulation of the superficial branches of the trigeminal nerve located extracranially in the face, namely the supraorbital, supratrochlear, infraorbital, auriculotemporal, zygomaticotemporal, zygomaticoorbital, zygomaticofacial, infraorbital, nasal and mentalis nerves (also referred to collectively as the superficial trigeminal nerve) are disclosed herein.

Abstract: Example methods, apparatus/systems and articles of manufacture for determining intensity of a biological response to a presentation are disclosed. An example method includes accessing galvanic skin response (GSR) data obtained from a subject while exposed to a presentation. The GSR data includes a plurality of trough-to-peak instances. The example method includes generating a GSR intensity profile by assigning trough-to-peak scores to corresponding ones of the trough-to-peak instances, defining a plurality of time windows, and assigning window scores to corresponding ones of the time windows based on the trough-to-peaks scores of the trough-to-peak instances occurring within the corresponding time windows. The example method also includes determining an effectiveness of the presentation based on the window scores of the GSR intensity profile.

Abstract: A system and method for training a student employ a simulation station that displays output to the student and receives input. The computer system has a rules engine operating on it and computer accessible data storage storing (i) learning object data including learning objects configured to provide interaction with the student at the simulation system and (ii) rule data defining a plurality of rules accessed by the rules engine. The rules data includes, for each rule, respective (a) if-portion data defining a condition of data and (b) then-portion data defining an action to be performed at the simulation station. The rules engine causes the computer system to perform the action when the condition of data is present in the data storage. For at least some of the rules, the action comprises output of one of the learning objects so as to interact with the student.

Abstract: An example system disclosed herein includes an analyzer to determine a first priming characteristic of media at a first location based on first neuro-response data and determine a second priming characteristic of the media at the second location based on second neuro-response data. The example system includes a selector to select a third location in the media after the first location or a fourth location in the media after the second location as a candidate location for introduction of advertising material based on the first priming characteristic and the second priming characteristic. The selector is to select the third location when the first priming characteristic indicates increased receptivity to the advertising material at the first location relative to the second priming characteristic and select the fourth location when the second priming characteristic indicates increased receptivity to the advertising material at the second location relative to the first priming characteristic.

Abstract: Provided are mechanisms and processes for more effectively monitoring infants to enhance caregiving and infant development. A system may include an infant monitoring device and a monitoring hub. The infant monitoring device includes sensors that gather measurement data. The monitoring hub receives the measurement data and analyzes the measurement data in relation to a learning receptivity model obtained from a remote platform. The measurement data is analyzed to predict a time and duration when an infant associated with the infant monitoring device will be receptive to learning.

Abstract: The present invention is directed to a method and system for predicting the behavior of an audience based on the biologically based responses of the audience to a presentation that provides a sensory stimulating experience and determining a measure of the level and pattern of engagement of that audience to the presentation. In particular, the invention is directed to a method and system for predicting whether an audience is likely to view a presentation in its entirety. In addition, the present invention may be used to determine the point at which an audience is likely to change their attention to an alternative sensory stimulating experience including fast forwarding through recorded content, changing the channel or leaving the room when viewing live content, or otherwise redirecting their engagement from the sensory stimulating experience.