Abstract: An injection pen that is suitable for being carried in the clothes of a user-patient for the selective use thereof. The pen includes a housing having a cartridge having a variable content disposed therein. The cartridge has an outlet formed therein. A piston is disposed therein for altering the fluid content of the cartridge. A pump rod is biased against the piston for altering the fluid content of the cartridge. A drive mechanism is provided for moving the pump rod at a continuous rate. The electromotor is controlled by an electronic control unit including a memory means for storing data, such as that corresponding to the reservoir stock status and that corresponding to the number of units of injection fluid to be delivered to the user-patient. A comparator means is provided for comparing the number of units of fluid with the reservoir stock status for controlling the electromotor. Preferably, the control unit is an integrated circuit including a processor.

Abstract: The invention relates to an infusion syringe pump which by means of a motor-gear unit drives a linearly movable drive member which is in engagement with the syringe plunger of an infusion syringe. According to the invention a position-defining element is connected only to the linearly movable drive member which actuates the syringe plunger of the infusion syringe. The position-defining element is functionally coupled to an absolute displacement pickup which is preferably constructed as linear potentiometer. By the control means according to the invention the absolute position of the syringe plunger can be determined.

Abstract: Failsafe apparatus and method are disclosed for controlling fluid flow from syringes. One or more syringes are positioned so that the piston of each syringe is caused to be precisely displaced to thereby safely deliver medicament from the syringe to a patient. To effect movement of each piston, a rack is provided, either as a part of the piston or secured thereto, and longitudinal movement of each rack is effected by rotating an associated pinion gear that is connected with a pulse-driven, stepper motor utilized in a power-efficient electromechanical configuration, with the operation of the stepper motor being accomplished through dual-redundant state machines controlled by a pre-programmed memory unit, and with the apparatus being repeatedly subjected to a plurality of error checks and data integrity verifications to assure continued proper operation.

Abstract: An enternal nutrition pump system operates in a cyclical manner with a period between cycles being selected in accordance with the desired fluid delivery rate. Each pump cycle may correspond to a single rotation of the rotor or a fractional rotation of the rotor. Rotor rotation may alternatively be sensed by utilization of magnetic sensors or by monitoring of the AC componment of current supplied to a DC motor driving the rotor.

Abstract: An angiographic injector device for use in x-ray photography for delivering contrast media to a patient at controlled rates and pressures. A processor elicits injection parameters from an operator or a pre-programmed injection module, and on the basis of the injection parameters, calculates appropriate control signals for use in a closed-loop servo system to actuate the plunger of a syringe containing the contrast media. Injection parameters includes flow rate, volume, duration, pressure limit and rise-fall time of flow rate. The device also includes control circuits for inhibiting the injection device in response to a contrast media pressure limit, failure in the processor or injection control system, or upon reaching a predetermined volume of injected media. A mechanical stop member cooperates with the control circuit for blocking movement of the syringe plunger upon reaching the predetermined injected volume.

Abstract: A syringe positioning device is disclosed for enhancing control of fluid flow from a syringe. A disposable unit that includes a syringe and rack mounted on a retaining clip is positionable on a drive unit so that, when so positioned, the piston of the syringe is precisely displaced to deliver medicament from the syringe to a patient. A non-disposable unit is also disclosed onto which a syringe and piston can be positioned so that the device thereafter also provides precise medicament delivery. The longitudinal movement of the rack is effected by rotating the pinion gear that is connected with a pulse-driven, power efficient stepper motor, with the operation of the stepper motor being controlled by a pre-programmed memory unit. A hinged rack is also disclosed, as is a one-way ball drive unit.

Abstract: An assembly is described for accurately and precisely controlling the position of a plunger in a syringe to deliver precise fluid volumes. The assembly includes a motor coupled to a lead screw that drives a bearing block along a linear guide rod to move the plunger of the syringe in a linear fashion. The position of the plunger is accurately controlled by attaching a digital encoder to the rotating motor shaft. The encoder and associated electronics output to a controlling processor that generates a series of regular pulses, typically 300 to 500 responsive to each motor revolution. Utilizing appropriate gear ratios of the motor and the lead screw, the number of pulses per full syringe stroke in typical applications can be on the order of one hundred thousand. The final position and the motion of the plunger (velocity and acceleration) can be controlled to within a few encoder pulses, thus precisely controlling the rate of delivery of the fluid and the volume of the fluid actually delivered by the syringe.

Abstract: Drive means for a small, lightweight, easily operated syringe infusion pump. A syringe is secured in a holder and the syringe plunger is moved by a pusher block of the drive means. The pusher block is advanced to the syringe plunger by squeezing a finger tab. This simultaneously decouples the pusher block from the internal drive and opens the antisiphon catch to allow quick and easy set-up. The pusher block is moved by the engagement of a floating halfnut on a threaded leadscrew. A force is applied to the halfnut by the block substantially near the midpoint of the leadscrew thereby greatly reducing force mechanisms that attempt to separate the leadscrew and halfnut. A relatively light first biasing means is on the block for applying a relatively small force between the halfnut and the leadscrew.

Abstract: Apparatus for displacing a piston in a chamber comprising a support member, a motor including a housing and a driving member that rotates relative to the housing and a driving axis, the driving member being rotatably mounted with respect to the support member, a torque resistor between the motor housing and the support limiting relative rotation between the two except when the torque between the two exceeds a predetermined amount, a piston driver including a driven portion threadedly connected to the driving member and a displacement portion that is axially displaced in response to relative rotation between the driving member and the driven portion, and a housing rotation detector to detect when the housing rotates relative to the support, indicating resistance to axial movement of the piston driver.

Abstract: A system for delivering a drug to a patient according to the preferred embodiment of the present invention is shown as including a plunger assembly reciprocally received in a reservoir for forcing the drug therefrom for delivery to the patient. The plunger assembly is axially advanced by the rotation of a lead screw rotatably mounted and axially movable with respect to the chassis. In a first axial position, the end of the lead screw deflects contacts of a switch member into electrical engagement which interrupts operation of the motor which rotates the lead screw. The lead screw is biased out of its first axial position such that the first end of the lead screw does not actuate the switch member and rotation of the lead screw is not interrupted.

Abstract: A method and apparatus for injecting a contrast media having means for preventing, operation thereof until the plunger of a syringe cartridge has been first placed in the fully extended position.

Abstract: Apparatus for automatically treating animals such as birds at a high speed. The apparatus includes a frame, a spindle mounted on the frame, drive means for rotating the spindle, and a table mounted on the spindle and provided with a plurality of spaced-apart bird supports capable of supporting birds immobilized in the neck area. A syringe and a suction device are supported on a support means that is freely mounted on the spindle and adapted to move with respect to the frame from a non-operative position to an operative position. The suction device has a nozzle provided with a perforated surface surrounding and extending vertically along the bird's neck area. The suction device serves to draw back an area of the neck skin before an injection is made with the syringe.

Abstract: An angiographic injector has an injector portion which includes a rotating turret for housing two angiographic syringes in readiness for injection. The injector further employs a driving mechanism for connecting with and controlling the movement of a syringe plunger once one of the syringes is in place for injection. Through the use of guide means on each syringe and corresponding alignment means on a pressure jacket, the syringe is alignably and securely mounted within the pressure jacket on the rotating turret. Each syringe plunger is releasably connected to the driving mechanism for an injection operation, and released from the driving mechanism when the injection operation has been completed, such that the driving mechanism can be withdrawn from the syringe relative to the plunger without drawing body fluid of a patient into the syringe. Various types of plunger release mechanisms for this purpose are disclosed.

Abstract: An infusion pump for controllable long-term injection of solutions from a syringe which can be emptied in a controlled manner for use with medical drugs in large doses. The infusion pump has a holding device for at least one syringe and an actuating device for the piston of the syringe which is connected to an electrical control drive, and an electrical battery for the drive. The actuating device is provided with a storage device for mechanical work acting through a detent member in the sense of the drive. The electrical control drive is adapted to release a retarding device when switched on, and to actuate the retarding device when switched off.

Abstract: The apparatus comprises an auxiliary pushbutton control for delivering insulin doses ahead of meals, an electric motor for producing a minimal angular advance movement of the administering syringe plunger pusher and programmable circuitry for multiplexing the minimal advance movements and providing programmed sequences of the multiplexed minimal advance movements at each operation of the pushbutton control.

Abstract: A fluid infusion pump driver device for pumping fluid from the chamber of a disposable cassette. The pump driver includes a reciprocatable plunger which is driven by a stepping motor. The motor and plunger are coupled through a universal joint which provides a threaded connection translating the incremental angular movements of the motor into incremental linear movements of the plunger, and the plunger is coupled directly to the frame through a flexible leaf spring to prevent wear in the threaded connection from generating undue noise or creating accuracy problems.

Abstract: A syringe injector for injecting liquids into patients comprising a syringe barrel with a slidable piston therein and a driver slidably extending into the barrel bore from the open end thereof behind the piston, where the driver includes a power supply and drive means operated by the power supply to cause at least a portion of the driver to move relative to the barrel to engage and propel the piston toward the discharge opening in the syringe barrel.

Abstract: An infusion device for a syringe includes a ratcheted stepper motor driven intermittently under the control of a control circuit to advance a syringe plunger driver. Different speeds are determined by the detected size of the syringe in the device. A clutch assembly disengageably connects the plunger driver to a drive belt driven by the stepper motor.A connector for a tubing set has a syringe-connect portion located in a recess of the connector, and cooperates with a force sensor in the device to detect occlusions. The connector has annular projecting portions with parallel, spaced apart actuating surfaces for engagement of the force sensor in either of two positions of the connector in the device. The connector is adapted to indicate to a sensor in which position it is located.

Abstract: A syringe for an injector utilizes a cylinder having a deformable wall portion in the outlet end. Excessive pressure within the syringe cylinder, or contact with the syringe piston at the end of its stroke distends the deformable wall portion of the cylinder, actuating a sensor which provides a signal.

Abstract: Injection device for medical purposes, designed for injection by using a manual hypodermic syringe. It includes a barrel part which in one end has a syringe needle and in the other end a flange; a plunger part having a plunger displaceable in the barrel part, said plunger performing movements, enabling medicine to be sucked into and respectively injected from the barrel portion, and having a gripping part connected with the plunger by means of a plunger rod. The device has an opening in one end, through which the injection syringe can at least partly be introduced into a cavity, and an inner part which is provided with a holding device for the barrel part which is changeable between a releasing position and a holding position, in which the barrel portion is held against movements in its longitudinal direction relative to the inner part. A displacement device is provided for displacing the plunger part between a fore and a rear displacement position.

Abstract: A bio-medical injector apparatus comprising a base unit having a skin engaging portion disposed at an angular orientation with respect to the longitudinal axis of the base unit for supporting and maintaining a hypodermic needle at an optimum angular orientation for effecting an injection procedure, a carriage assembly reciprocally mounted on the base unit and carrying the hypodermic needle simultaneously therewith, a motor drive unit operably connected with the hypodermic needle for the preloading thereof with a suitable medication, a solenoid secured to the base unit and operably connected with the carriage assembly for a controlled reciprocation thereof for effecting the injection operation of the needle, and an electronic circuitry operably connected between a power supply and the motor drive and the solenoid for creating the logic necessary to perform the functions of the injector apparatus.

Abstract: A portable infusion pump for controllably supplying a programmed volume of medicant to a patient. The apparatus generally comprises a small, portable container having a keyboard for programming the mode of operation and operating parameters, whereby a microprocessor controls the pump in the various BASAL, SUPPLEMENTAL OR MANUAL dose delivery modes. The apparatus also contains a photo-coupler controlled driven lead screw assembly for controlling the stroke of the syringe plunger, whereby metered doses of the medicant are injected into the patient; display means for confirming programmed inputs; means for audibly warning of error conditions; and means for recording the total cummulative dosage delivered.

Abstract: A pipette is described comprising a piston for generating pressure to eject liquid and a motor for moving the piston. A drive-decoupling mechanism is interposed between the motor and piston to allow the motor to decouple and overtravel without causing the piston to overtravel.

Abstract: An apparatus for infusing liquid medication such as insulin into a living body has a memory for storing a basic pattern and meal patterns which decide the medication infusion dose in accordance with time. The basic pattern is designated under ordinary conditions, with a meal pattern being designated for a predetermined period of time when desired. With the passage of the predetermined period, the basic pattern is restored, the address of the basic pattern being designated according to the actual time. When a pattern is selected, the one actually addressed and read out of the memory is that appropriate for the time of day. The pattern information read out of the memory is applied to means for infusing the liquid medication into the living body, the dose of the medication conforming to the specific pattern.

Abstract: An injector for medical uses comprises a housing (30) on which a first holder (65) for holding the front end of a syringe (13) is movably mounted. A slide (32) is movable relative to the housing (30). A second holder (66) for attachment of the syringe piston (14) is mounted to the slide (32). When the force exerted by the syringe cylinder (12) on the first holder (65) reaches an overload condition, the first holder (65) moves counter to the action of a spring (58). An actuating element (62) connected to first holder (65) then actuates a switch (48) whereby the motor drive of the slide (32) is turned off.

Abstract: An injector for squeezing liquid from a medical syringe is disclosed. On a housing (10), a first holder is (11) fastened. A first end of a syringe cylinder is joined to the first holder (11). The syringe piston (15) is joined to a second holder (13). The second holder (13) is fastened to a slide (12) which is displaceable relative to the housing (10). The drive of the slide (12) is effected by way of a pipe (26) and a ball gear (27, 28) on a spindle (28). The end of the spindle (28) is connected with the slide (12) through a free-wheeling mechanism. The spindle (28) can be rotated by hand with a rotary button (30). When the free-wheeling mechanism is released, the slide (12) can be pulled linearly into a desired position. The ball gear drive mechanism (27, 28) ensures that when the motor is turned on, the slide (12) is driven at once without first requiring an engagement of a tooth system or a screwthread.

Abstract: Variable rate pump for insulin delivery has as its pumping unit a syringe. A motor is connected to advance the syringe and electric signal pulses are produced during syringe advance. A control system permits selection of the interval between command pulses to maintain the desired base insulin delivery rate. A separate circuit drives the motor and syringe to deliver a predetermined bolus of insulin. Alarm circuits are connected to monitor the various system requirements and signal when they are not fulfilled.

Abstract: A mechanism for screw drive and syringe plunger engagement and disengagement for a syringe infusion pump, wherein a split-nut pair are moveable into and out of engagement with a lead screw by means of rotary cam control, the rotary cam being keyed with a crank disk that is coupled to a crank arm, which operates as the syringe plunger mover. The crank arm is rotatable into and out of engagement with the syringe plunger, such rotation also causing the split-nut pair to move into and out of engagement with the lead screw. Index and cam means are carried by the crank arm to aid in proper alignment with the syringe plunger, and a sensor is provided for monitoring proper engagement of the crank arm with the plunger.

Abstract: Method and apparatus for injecting fluids into patients at a controlled rate from an ampule containing the injecting fluid with a sliding piston therein to force the fluid from the ampule into the patient using a drice system which incrementally and successively advances the piston in the ampule to meter the fluid into the patient.

Abstract: Anaesthetic may be injected directly into the bone using a syringe in combination with a mechanism for causing the syringe needle to oscillate about its axis. The mechanism may be driven by a drive unit of the type conventionally used to power dental instruments.

Abstract: Method and apparatus for injecting fluids into patients at a controlled rate from an ampule with a tubular side wall closed at one end with a penetrable plug and a sliding piston in the side wall to force the fluid through an opening in the penetrable member using either a long duration injector with an expelling means to move the ampule piston, drive means for operating the expelling means, and control means for incrementally and successively connecting and disconnecting the drive means to the expelling means or a short duration injector with a spring drive or a fluid pressure drive to move the ampule piston and meter the fluid through a metering device.

Abstract: Method and apparatus for injecting fluids into patients at a controlled rate from an ampule containing the injecting fluid with a sliding piston therein to force the fluid from the ampule into the patient using a drive system which incrementally and successively advances the piston in the ampule to meter the fluid into the patient.

Abstract: Apparatus and method for injecting fluids into patients at a controlled rate from an ampule containing the injecting fluid with a sliding piston therein to force the fluid from the ampule into the patient using a drive system which incrementally and successively advances the piston in the ampule to meter the fluid into the patient.

Abstract: An improved drive is provided for a syringe having a barrel and a plunger. The drive utilizes an electric motor which has an axial shaft that moves back and forth axially when the shaft is prevented from rotating. A syringe barrel holder is fixed relative to the electric motor housing and a plunger holder is rigidly fixed to the shaft. When the electric motor is energized, the plunger holder will move back and forth relative to the syringe barrel holder. A plurality of switches for controlling the electric motor are positioned in fixed locations relative to the motor housing. The plunger holder is operative to actuate and deactuate the switches during axial travel of the shaft.

Abstract: A linear actuator which can apply high forces is described, which includes a reciprocating rod having a threaded portion engaged by a nut that is directly coupled to the rotor of an electric motor. The nut is connected to the rotor in a manner that minimizes loading on the rotor, by the use of a coupling that transmits torque to the nut but permits it to shift axially and radially with respect to the rotor. The nut has a threaded hydrostatic bearing for engaging the threaded rod portion, with an oilcarrying groove in the nut being interrupted.

Abstract: An implantable device for dispensing a medicament in two modes; a basal delivery rate and an augmented rate. The device includes a permeable elastic material adapted to be repeatedly compressed by a solenoid operated piston. The device delivers a basal rate when the piston is inoperative and an augmented rate when the permeable elastic material is compressed. The device is suitable for delivering insulin in an "artificial endocrine pancreas".

Abstract: An injection system for suspensions and solutions having five cartridges supported on a cartridge support. The cartridges are connected to a coalescing disc with five inlet passages and a single output passage with a feed line connected to the single passage. Suspensions and solutions supplied to the cartridges are selectively injected into a test subject by supplying a saline solution to the cartridge from a syringe pump through a selector which selects the cartridge to which the saline solution is supplied.

Abstract: Apparatus for driving a medical syringe plunger into its barrel at a variable controlled rate comprises an elongate support along which the syringe is secured, an electric motor, a transmission assembly drivably coupled with the motor to close the plunger into the barrel, a drive control for pulsing the motor to effect repeated constant incremental movements of the plunger through the transmission assembly, and a safety control operable to inhibit the drive control in response to continuous energization of the motor beyond a predetermined period. The safety control conveniently involves a capacitor charged by the motor pulses, and a latch activated by an "excess" charge on the capacitor relative to a normal situation.

Abstract: An apparatus for the dosed dispensing of a liquid by means of an injection device equipped with a motor-driven spindle mechanism, a cylinder and a piston, one end of the piston being axially displaceable in the cylinder and the other end being operatively connected with one end of a spindle shaft of the spindle mechanism. At the opposite end of the spindle shaft there is provided a first scale ring connected with the spindleshaft and a second scale ring which engages with the first scale ring. A coupling element connects the second scale ring with an adjustment device, the second scale ring being rotatable and thus adjustable with respect to the first scale ring by axially disengaging or declutching the same. Both of the scale rings are equipped with at least one stop means for limiting the adjustment path of the second scale ring for setting the volume of the liquid to be dispensed or dosed.

Abstract: A fluid dispenser including a syringe having a reciprocating syringe plunger for controlling syringe fluid intake and discharge and a traveling slide connected to the plunger for driving the plunger. The traveling slide is bearing mounted in sliding relationship on a fixed shaft and is driven therealong by a pinion gear engaging a rack secured to the slide.

Abstract: Method and apparatus for injecting fluids into patients at a controlled rate from an ampule with a tubular side wall closed at one end with a penetrable plug and a sliding piston in the side wall to force the fluid through an opening in the penetrable member using either a long duration injector with an expelling means to move the ampule piston, drive means for operating the expelling means, and control means for incrementally and successively connecting and disconnecting the drive means to the expelling means or a short duration injector with a spring drive or a fluid pressure drive to move the ampule piston and meter the fluid through a metering device.

Abstract: An automatic injector device operating stroke-by-stroke, comprising a frame whose shape is substantially similar to that of a revolver, a removable injection syringes comprising a syringe body, a syringe piston and at least one injection needle, a syringe-cradle carrying the said syringe and itself supported by the said frame, drive means on the one hand actuating in reciprocating motion the cradle-syringe assembly, and on the other hand actuating the syringe piston, and means for manually starting at least one injection, such as for example a trigger, which operates at least a part of said drive means.

Abstract: An automatic injection device for small animals. The device comprises a work plate on which an animal to be injected can be positioned, a syringe mounted on the opposite side of the work plate from the side on which the animal to be injected is positioned during use of the device, first means for moving the syringe back and forth between a first position in which the syringe needle is entirely withdrawn on said opposite side of the work plate and a second position in which the syringe needle protrudes through an aperture in the work plate, and second means for detecting the presence of an animal to be injected in position on the work plate and for activating the first means. The first means comprises a single-action pneumatic motor and means for retaining the syringe in its second position while the mounting of the syringe is adjusted.

Abstract: A clockwork device for driving a hypodermic syringe comprises a device for holding a syringe and automatically injecting predetermined amounts of fluid into a patient at a controlled rate over a period of time. The device comprises a clockwork mechanism, a syringe coupled thereto and an exterior housing containing the various components. The clockwork mechanism is mounted parallel to the overall length of the syringe within the housing to minimize the size of the device. A two-way releasable clutch is utilized to connect the clockwork mechanism to the syringe driving mechanism for ease of retracting or advancing the driving mechanism.

Abstract: An apparatus for injecting fluid, specifically contrast media, into the vascular system of a human being or other animal. The apparatus comprises a head portion and a control unit. The head portion includes the motor and drive components, and carries a removable syringe cartridge containing the fluid. Integral with the head portion is a pressure jacket for housing the syringe cartridge, and a piston plunger for forcing the fluid out of the syringe cartridge, through a catheter and into the vascular system. The control unit includes the mechanism for selecting delivery parameters, and circuitry for controlling the delivery of the contrast media into the vascular system. Also disclosed is a syringe cartridge designed to cooperate with the apparatus for injecting contrast media.

Abstract: A small, portable, constant withdrawal device is connected to tubing, including a catheter, whose internal walls are coated with heparin. The catheter is inserted intravenously through a disposable needle into a subject such as a human being. The subject may then move about for a selected period when blood is being slowly withdrawn at a prescribed rate and collected in a container within a housing supporting the device. The collected blood may then be analyzed to permit the measurement of the integrated concentration of growth hormone or any substance whose concentration in blood fluctuates widely.In addition, a portable microdiffusion chamber is incorporated between the indwelling catheter and the extra corporal tubing and is electrically connected through a sensing probe to an associated portable sensory responsive device. This permits analyzation of the extracted blood to determine the in vivo concentration of circulating concentrations of the diffusable fraction of biological materials in the blood.

Abstract: An apparatus for dispensing drugs and other medications within the body leaves the patient ambulatory and is adapted to be entirely implanted and to dispense such substances over a long period of time, e.g., one to several years, in accordance with the actual needs of the patient. A self-powered dispensing device stores a single or plural substances in powdered, liquid, or other dispensable form and utilizes a compressible container, i.e., a bellows, for withdrawing such substances from storage and dispensing to the body. The dispensing operation may be on a fixed schedule or may be controlled by monitoring single or plural sensors implanted in the body and evaluating the sensed data in order to control both the conditions under which and the kind of dispensing which takes place. Dual dispensers and dual medication may be employed.

Abstract: The automatic injection device of the invention comprises an injection syringe having a syringe body provided with a lateral injection-liquid supply tubulure, retention means for retaining the animal to be treated, enabling the latter to be placed in a given transverse position and at a given angle with respect to the syringe, syringe displacement means for advancing and withdrawing the syringe at each injection, and piston displacement means for displacing the piston with respect to the syringe body. Such a device enables for example about at least 2000 chicks to be vaccinated per hour, while at the same time ensuring a dosing accuracy on the order of 1/100 and an exact location of the point of injection.