Intersecting At Interaction Region (e.g., Comparator) Patents (Class 137/823)
  • Patent number: 8656958
    Abstract: A method of fabricating an elastomeric structure, comprising: forming a first elastomeric layer on top of a first micromachined mold, the first micromachined mold having a first raised protrusion which forms a first recess extending along a bottom surface of the first elastomeric layer; forming a second elastomeric layer on top of a second micromachined mold, the second micromachined mold having a second raised protrusion which forms a second recess extending along a bottom surface of the second elastomeric layer; bonding the bottom surface of the second elastomeric layer onto a top surface of the first elastomeric layer such that a control channel forms in the second recess between the first and second elastomeric layers; and positioning the first elastomeric layer on top of a planar substrate such that a flow channel forms in the first recess between the first elastomeric layer and the planar substrate.
    Type: Grant
    Filed: October 31, 2007
    Date of Patent: February 25, 2014
    Assignee: California Institue of Technology
    Inventors: Marc A. Unger, Hou-Pu Chou, Todd A. Thorsen, Axel Scherer, Stephen R. Quake, Markus M. Enzelberger, Mark L. Adams, Carl L. Hansen
  • Patent number: 8475743
    Abstract: Multilevel microfluidic devices include a control line that can simultaneously actuate valves for both sample and reagent lines. Microfluidic devices are configured to contain a first reagent in a first chamber and a second reagent in a second chamber, where either or both of the first and second reagents are contained at a desired or selected pressure. Operation of a microfluidic device includes transmitting second reagent from the second chamber to the first chamber, for mixing or contact with the first reagent. Microfluidic device features such as channels, valves, chambers, can be at least partially contained, embedded, or formed by or within one or more layers or levels of an elastomeric block.
    Type: Grant
    Filed: April 13, 2009
    Date of Patent: July 2, 2013
    Assignee: Fluidigm Corporation
    Inventors: Geoffrey Facer, Brian Fowler, Emerson Cheung Quan, Marc Unger
  • Patent number: 8343428
    Abstract: A microchip including a first substrate with a groove formed on a substrate surface or a pass-through hole passing in a thickness direction of the substrate, and one or more second substrates laminated on a surface of the first substrate; the microchip including an optical measurement cuvette consisting of a space configured by the groove or the pass-through hole, and a substrate surface of the second substrate; wherein a side wall surface of the second substrate is positioned on an inner side than a side wall surface of the first substrate in at least one part of a side wall surface of the microchip, and a method of using the same are provided.
    Type: Grant
    Filed: October 24, 2008
    Date of Patent: January 1, 2013
    Assignee: Rohm Co., Ltd.
    Inventors: Akinori Yokogawa, Toshihiro Mori
  • Patent number: 8105551
    Abstract: A microfluidic device and a method of fabricating the microfluidic device are provided. The microfluidic device includes: a platform including an upper substrate and a lower substrate that are bonded to face each other; a microfluidic structure obtained by forming grooves in the lower substrate; a lower substrate protrusion pattern including an outline protrusion that protrudes from the lower substrate toward the upper substrate along an outline of the microfluidic structure; and an adhesive layer disposed between the lower substrate protrusion pattern and the upper substrate in order to bond the upper substrate and the lower substrate to each other. The lower substrate protrusion pattern only supports the upper substrate, and remaining portions of the lower substrate except for the lower substrate protrusion pattern do not have structures for supporting the upper substrate.
    Type: Grant
    Filed: April 3, 2009
    Date of Patent: January 31, 2012
    Assignee: Samsung Electronics Co., Ltd
    Inventors: Jongmyeon Park, Jeonggun Lee
  • Publication number: 20080121300
    Abstract: An object of the present invention is to provide an accumulator including a flow damper which is capable of performing a control so that a vortex may not be formed in a vortex chamber at the time of a large flow injection without requiring huge labors and fabrication costs. The flow damper is configured of a colliding jet controller (a bevel or a projection) for controlling a colliding jet composed of a jet from a large flow pipe and a jet from a small flow pipe flowing into a vortex chamber at the time of a large flow injection so that the colliding jet may proceed directly to an outlet without forming a vortex in the vortex chamber. The colliding jet controller is provided at a junction of an inner surface of the small flow pipe and an inner surface of the vortex chamber.
    Type: Application
    Filed: November 28, 2006
    Publication date: May 29, 2008
    Applicant: MITSUBISHI HEAVY INDUSTRIES, LTD.
    Inventor: Tadashi Shiraishi
  • Patent number: 4468961
    Abstract: Presented is a method and means for monitoring the angle of attack of an airfoil and displaying the monitored angle of attack as a visual reference to the pilot.
    Type: Grant
    Filed: December 29, 1982
    Date of Patent: September 4, 1984
    Inventor: Lauren V. Berg
  • Patent number: 4164961
    Abstract: A fluidic flow or pressure regulator which utilizes a linear and a non-lir resistance arranged in parallel supplying control passages to change the direction of a jet as a function of the pressure of an unregulated fluid source. An output means is provided which can supply fluid having pressure which is a desired function of the unregulated pressure, including a constant pressure. One embodiment forms the variable direction jet solely from the two control passages while another embodiment uses the control passages to change the direction of a power jet.
    Type: Grant
    Filed: July 28, 1977
    Date of Patent: August 21, 1979
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: Tadeusz M. Drzewiecki, Francis M. Manion
  • Patent number: 4104645
    Abstract: Several coincidence ink jet array systems are provided wherein each ink jet has two inlet passages communicated to an outlet orifice. An ink droplet is expressed from the orifice only when pressure pulses applied to the inlet passages coincide at the orifice.In one system, each inlet passage of a jet is communicated to a respective transducer and each transducer is connected to a respective electronic driver. In this system, the number of electronic drivers and transducer chambers are substantially less than the number of ink jets. These transducer chambers are time shared for expressing an ink droplet. Actuation of the two transducer chambers communicated to a particular jet, in such a manner that the pressure pulses generated by the respective transducers coincide at the orifice, will effect expression of a droplet therefrom.In another system, a master transducer chamber is communicated to one inlet passage of each jet.
    Type: Grant
    Filed: October 12, 1976
    Date of Patent: August 1, 1978
    Assignee: Xerox Corporation
    Inventor: Kenneth H. Fischbeck