Abstract: A method of dispensing a fluid product by using a dispensing bottle which includes a rigid body in which a reservoir for packaging the fluid product is formed and a device for taking off the packaged fluid product that is mounted sealingly on the body, the body also being equipped with a valve for filling the reservoir, the method, prior to the initial filling of the reservoir with fluid product, making provision for putting the empty reservoir in communication with an air suction device and activating the device in order to create a negative pressure inside the reservoir; subsequently effecting the initial filling of the reservoir by putting a product source in sealed communication with the reservoir by means of the valve; dispensing the packaged fluid product by actuating the take-off device.

Abstract: An inspection machine for inspecting the volume of liquid contained by a bottle filed to its defined fill height. A head is lowered and has a sealing plate which seals the open finish of a bottle. A fill tube assembly is part of the head and continues to be lowered until a level sensor is located to sense liquid at a pre-fill level. High and low pressure water lines which are a part of the fill tube assembly are operated to fill the bottle to the pre-fill level. The sealing plate is released and then the process is repeated lowering the sensor to the post-fill level and operating only the low-pressure line to fill the bottle to the post-fill level. The total liquid filling the bottle is then computed.

Abstract: The present invention relates to an ink tank for an ink jet printer. The invention further relates to a method of manufacturing the ink tank, as well as well as a method of refilling the ink tank. The ink tank includes an ink tank body and an ink tank lid bonded to the ink tank body at a bond joint. The ink tank lid comprises an opening that leads to a holding area that is adapted to contain a capillary media therein. The holding area comprises a wall that forms a boundary between the capillary media and an enclosure defined by the ink tank body and the ink tank lid. The opening is sized to permit an insertion and removal of the capillary media to and from the holding area when the ink tank lid is bonded to the ink tank body at the bond joint.

Abstract: Systems, devices, and methods for filling containers with radioactive materials are described. In certain embodiments, the systems comprise a shielding material that substantially defines a chamber and, preferably, substantially blocks radioactivity, a conduit extending through the shielding material into the chamber, and a securing unit that is disposed in the chamber proximal to the conduit and is adapted to receive a container through the conduit.

Abstract: Methods and apparatus are disclosed for loading a therapeutic substance or drug within a lumenal space of a hollow wire having a plurality of side openings along a length thereof that forms a hollow drug-eluting stent with a plurality of side drug delivery openings. Loading a drug within the lumenal space of the hollow stent includes a drug filling step, in which the drug is mixed with a solvent or dispersion medium. The lumenal space may be filled with the drug solution or suspension in a reverse fill process and/or a forward fill process. After the drug filling step, a solvent or dispersion medium extracting step is performed to extract the solvent or dispersion medium from within the lumenal space such that only the drug remains within the hollow stent. A stent cleaning step may be performed to an exterior surface of the hollow stent.

Abstract: Among other things, a communication line is attached along a target surface of a building by laying out the line from a tool. An outer surface of the line is in a temporarily tacky condition as the line is laid out along the surface. The line is in the temporarily tacky condition based at least in part on an adhesive component having been pre-applied to the outer surface of the line. The line becomes non-tacky after it has been attached.

Abstract: A drug-eluting stent delivery system has a balloon disposed about at least a portion of a catheter, the balloon having a first end and a second end and a working length therebetween, the first end and the second end each including a tapered portion, each tapered portion being attached to the catheter, the balloon being inflatable from a collapsed configuration to an inflated configuration. A drug-eluting stent has a first end and a second end, the first end and the second end each including a tapered portion, wherein the drug-eluting stent is disposed over the balloon such that at least a portion of the first end and the second end of the balloon are covered by the tapered drug-eluting stent.

Abstract: A powder packaging includes space for containing powder, an outlet opening for the powder, and a dosing device positioned on the outlet opening, the powder dosing device including a dosing body having a first closing part, a second closing part and a dosing chamber between the closing parts. The dosing body is movable between a filling position in which the dosing chamber is accessible for powder in the powder containing space and the second closing part closes off the outlet opening, and a dosing position in which the first closing part closes off the outlet opening and the dosing chamber allows powder to leave the dosing chamber and thus to exit the powder containing space.

Abstract: The invention relates generally to implantable drug delivery devices. Devices having a single drug chamber configuration, a divided drug chamber configuration and a compact dual-drug configuration are described. The devices have features to prevent clogging of the dispensing catheter and the creation of a local vacuum caused by the dispensing of the drug fluid. Also provided are features of a failsafe refilling process, automatic refill notification, and performance verification process. The divided drug chamber configuration enables frequent or continuous minute doses. A dual-drug chamber configuration uses self-locking refill containers to prevent mismatching between refill containers and drug chambers.

Abstract: A stent deployment system, handle, and method of loading of a medical device are provided. The system includes an outer catheter having an inner liner extending past the end of the outer catheter and an inner catheter disposed within the outer catheter. The inner liner is inverted and attached to the inner catheter. Relative movement between the outer and the inner catheters can urge the inner liner to peel away from the medical device. A handle is disposed at the proximal end of the outer catheter, and may include a splitter configured to slice the wall of the tubular member. The handle may also include a rotatable mechanism that can be attached to the tubular member. Rotation of the rotatable mechanism retracts a portion of the tubular member into the handle and winds the sliced portion about the rotatable mechanism.

Abstract: Provided is a refill cap cartridge engageable with a bottle during usage thereof. The refill cartridge includes an upper body and a lower body defining a cartridge reservoir. The upper body is configured to be engageable with the body, while the lower body is configured to be insertable within the bottle opening. The refill cartridge additionally includes a plug having an upper plug portion defining an upper plug head and a lower plug portion defining a flared end portion. The plug is engageable with the cap and is moveable relative to the cap between a sealing position and a dispensing position.

Abstract: An inkjet printer cartridge refilling system is described. The system may include a plurality of fixtures or adapters that are configured to hold inkjet printer cartridges. The adapters allow a variety of different configurations of inkjet printer cartridges to be refilled and cleaned by mating the cartridges to universal stations on the refilling system.

Abstract: A food storing apparatus capable of dispensing a content stored in the apparatus is disclosed. The food storing apparatus includes a button tray composite device configured to function as a switch to control the dispensation of the content, but also configured to function as a tray for receiving a residual content discharged after the content dispensation.

Abstract: An apparatus includes a housing, a medicament container, an actuator, and a biasing member. The actuator is configured to move the medicament container within the housing when the actuator is moved from a first configuration to a second configuration. The actuator includes a gas container and a puncturer. When the actuator is in the first configuration, a portion of the puncturer is disposed apart from the gas container. When the actuator is in the second configuration, the portion of the puncturer is disposed within the gas container. The gas container has a longitudinal axis offset from a longitudinal axis of the medicament container. The biasing member is configured to bias the actuator toward the second configuration.

Abstract: A printhead assembly is described including multiple printheads, a manifold and multiple inlet tubes. The printheads each include: a fluid inlet to receive fluid into the printhead; and a set of one or more nozzles to deposit fluid on a substrate. The manifold is connected to the printheads and includes: a fluid inlet duct configured to receive fluid for delivery to the printheads; multiple fluid inlet channels for connecting the fluid inlet duct to the printheads; and multiple fluid inlet valves configured to control a flow of fluid from the fluid inlet duct to each of the fluid inlet channels. The inlet tubes each have a proximal end integral to either the manifold or one of the printheads, and a distal end connected to either the manifold or said printhead with a single fluid-tight connection.

Abstract: The grommet used for sealing the charging opening in a pressurized dispensing container is designed so that it can be held in a venting state prior to the charging of the propellant chamber. The design involves an annular ridge above the neck of the grommet and an annular groove above the annular ridge. In that fashion, the grommet can be held loosely on the opening in the base of the container. Flats or cutaways on the crown and groove assure passageway between the propellant chamber and the outside so that air can be taken in and expelled from the propellant chamber during the product loading stages.

Abstract: The present disclosure provides a nitrogen tire inflation and deflation system and associated usage methods. In one exemplary embodiment, the system includes a dispenser and a nitrogen storage device along with an associated usage method. In another exemplary embodiment of the present disclosure, a decommissioned pay phone is converted into an air or nitrogen dispenser. The conversion utilizes the form-factor and payment component of the pay phone with the additional of parts to regulate air flow. Advantageously, this provides an environmental solution to waste disposal of decommissioned pay phones. The air/nitrogen dispenser of the present disclosure can be placed at gasoline stations, convenience stores, car washes, and the like.

Abstract: In a dispensing appliance for dispensing a beverage from a powdered beverage container, a cartridge includes a container containing powdered beverage, and a dispenser on the container operable to dispense powdered beverage from the container. The appliance includes a mount for removably supporting the cartridge on the dispensing appliance, and a drive system configured for operative connection with the dispenser upon loading of the cartridge into the mount. The drive system is operable to operate the dispenser to release powdered beverage from the container. The beverage may be dispensed from the appliance in its powder form, or mixed with a liquid and dispensed generally in a liquid form. In a method of refilling a dispensing appliance, an empty cartridge of powdered beverage is replaced with a new, substantially full cartridge of powdered beverage with the cartridge dispenser operatively connected to the drive system of the appliance.

Abstract: The present invention provides holding devices and methods for using the same. One aspect of the invention provides a holding device configured to hold a container having a dose or multiple doses of a liquid medicine with a needle-piercable cap. The holding device includes a holder comprising a split barrel and a base. Another aspect of the invention provides a method of loading a syringe with a liquid medicament held in a container. The method includes: providing a holding device including a holder including a split barrel and a base; mounting the holding device on a surface; placing the container into vial holder; and using two hands to draw the liquid medicament from the vial into the syringe.

Abstract: A reservoir filling aid for a reservoir of a medical infusion pump is disclosed. The reservoir filling aid comprises a main body for supporting the reservoir during the filling of the reservoir with a medical serum and a supply vial adapter end positioned at a first end of the main body. The supply vial adapter end comprises a plurality of flexible tabs extending from the supply vial adapter end for interfacing with a supply vial containing the medical serum and a shaped ring for housing the plurality of flexible tabs and the supply vial while in a closed configuration to establish a fluid connection between the supply vial and the reservoir. The interior of the supply vial adapter end may also have a spiral track for additional security. A removable adapter may be fitted on the top of small supply vials.

Abstract: The present invention provides holding devices and methods for using the same. One aspect of the invention provides a holding device configured to hold a container having a dose or multiple doses of a liquid medicine with a needle-piercable cap. The holding device includes a holder for the container, a base, and an angular adjustment linkage between the base and the holder. Another aspect of the invention provides a method of loading a syringe with a liquid medicament held in a container. The method includes: providing a holding device including a holder for the container, a base, and an angular adjustment linkage between the base and the holder; placing the holding device on a surface; placing the container into the holder; and using two hands to draw the liquid medicament from the container into the syringe.

Abstract: A filling device for a needle-free injector system is provided that is adapted to sterilely deliver a predetermined amount of an injectate from a vial to a plurality of cartridges. The filling device normally includes a single-use fluid path disposed between the vial and a receiving cartridge. The fluid path may include a vial connector adapted to couple to a vial, a filler head, and a conduit connecting the vial connector and filler head. The filling device typically further includes a pump coupled to the fluid path and adapted to propel the injectate from the vial to the receiving cartridge, and a cartridge-advancing element. Activation of the cartridge-advancing element is adapted to sequentially advance empty cartridges into a position opposite the filler head. Also provided are disposable fluid path kits and methods of using the filling device.

Abstract: An apparatus for preparing a syringe for use in injecting a medication includes a body extending obliquely upwardly, with a carriage slidably secured thereto and adapted to support a syringe. The syringe is fixedly secured to the body, and translation of the carriage proximally and distally knocks off the needle protective cap and the plunger cap. A trough aligned with the syringe enables an injectant vial to be translated downwardly to drive the needle into the vial. A plunger driver is slidably mounted on the body to engage the syringe plunger and assist its withdrawal and retraction. A protective cap holder may be placed on the trough to engage and remove the protective cap for later use.

Abstract: Bone cement mixing and delivery devices and methods of using the devices are provided. The bone cement mixing and delivery devices and methods comprise a container having a bottom opening that can be sealed by a spacer in a syringe where movement of the plunger of the syringe moves the spacer away from the bottom opening in the container to dispense bone cement into the syringe. In some embodiments, the devices and methods increases efficiency and reduce the mess associated with transferring the bone cement to the syringe for delivery to a patient.

Abstract: A spill-proof aerator is disclosed that is adapted to flamelessly diffuse a liquid solution into the atmosphere. The device comprises a liquid solution having less than 20% volatile organic compounds housed in a vessel with at least one wall, wherein an opening is disposed in the wall. The device further includes a wick assembly including at least a wick of porous material capable of being disposed in the opening of the vessel for at least partial submergence in the liquid solution. The wick is further disposed for drawing up the liquid solution thorough capillary action. The wick assembly is reusable and adapted to removably seal the opening in the vessel.

Abstract: The disclosure relates to a method of providing in a powder provider device a target dose of an active pharmaceutical ingredient present in a powder preparation. The active ingredient in a powder sample is analyzed and a powder volume corresponding to the target dose is calculated. The positions of wall portions forming a hole are adjusted relative to each other for receiving the calculated powder volume in the hole. The disclosure also relates to a method of providing a target volume of powder, a powder provider device and a use of a powder dosing system.

Abstract: In the present invention methods for storing gaseous hydrogen employing an ionic liquid are disclosed. The ionic liquid is used to displace the volume in the storage tanks. By displacing the volume in the storage tanks with the ionic liquid, the storage pressure can remain constant and the “stranded” gas can be eliminated. This constant pressure will also allow for a reduction in the number of storage tanks needed to provide the required inventory at hydrogen fueling stations. In addition, this constant pressure will provide a complete and fast fill to the vehicle.

Abstract: A medical device is provided with a porous region including a reservoir zone including a polymer and a protective zone between adjacent tissue and the reservoir zone that restricts the tissue from direct contact with the polymer.

Abstract: A container and method for filling same. The container includes a penetrable and resealable portion that is resealable, and a container body having a sealed empty chamber in fluid communication with the penetrable and resealable portion for receiving therein a substance. The container also includes a base, a mid-portion, and an upper portion axially spaced from the base on an opposite side of the mid-portion relative to the base. Each of the base and upper portion define a laterally-extending dimension greater than a maximum laterally-extending dimension of the mid-portion. The method of filling the container includes penetrating the penetrable and resealable portion with an injection member and introducing a substance into the chamber, withdrawing the injection member while engaging the base of the body to substantially prevent upward movement of the body, and applying energy to the penetrable and resealable portion to form a gas-tight seal.

Abstract: A liquid discharge member includes discharge ports, and a first opening and a second opening that communicate with the discharge ports. A liquid supply member includes a first filter disposed in a gravitational direction and in a disposed direction, a first containing chamber containing the first filter, a second containing chamber containing the second filter, a first flow path connecting the first opening and the first containing chamber, and a second flow path connecting the second opening and the second containing chamber. The second filter and the first and the second flow path are disposed in an area between a surface perpendicular to the disposed direction and parallel to the gravitational direction and going through one end of the length of the first filter and a surface parallel to the first surface and going through the other end of the length of the first filter in the disposed direction.

Abstract: This spraygun (1) comprises a body (11) and, housed in a proximal part (11.1) of the body (11), a tank (10) extending along a main axis (X10). This spraygun also comprises atomizing means (5) in a distal part (11.2) of the body (11) comprising an atomizing member (51) designed to atomize the coating product generally in an atomizing direction (Y50). The atomizing direction (Y50) and the main axis (X10) of the tank are convergent.

Abstract: A dump chute adaptor includes an adaptor housing having a housing interior and a conduit coupling carried by the adaptor housing and disposed in fluid communication with the housing interior.

Abstract: A method of bulk handling of a liquid agricultural chemical includes securing an above ground farm container to the ground at a farm location with an input port defined in a top thereof; pumping the chemical from a container at a dealer location into a transport vehicle, driving the transport vehicle to the farm location, and pumping the agricultural chemical into the input port; pumping the agricultural chemical from the farm container through an output port in the top of the farm container into a carry tank on a farm vehicle; and driving the farm vehicle to a field location and pumping the agricultural chemical from the carry tank into a chemical applicator for application on a field. A suitable chemical container for the farm location has an outer shell and inner molded tank with an upper portion that protrudes laterally outward over the top edge of the shell.

Abstract: Corrosion management systems protecting against or managing corrosion of various components in generally vertically oriented structures, that can be located one or more of aboveground and underground. The corrosion management system includes a dispenser system that dispenses at least one corrosion inhibitor to the structure desired to be protected at a plurality of different vertical heights. Methods for utilizing corrosion management systems and protecting structures therewith are also disclosed.

Abstract: A system for deliverying a therapeutic amount of nitric oxide can include a reservoir assembly, a gas supply, and a delivery conduit including a first cartridge, wherein the first cartridge can include a surface-activated material saturated with an aqueous solution of a reducing agent.

Abstract: A manufacturing system for making paints from prepaints, along with a method related thereto.

Abstract: A dispensing tool is disclosed which includes an exchangeable container having a main component A, a container having a minor component B, a mixer for the components A and B, and an expelling device for at least one of the containers, the expulsion into the mixer of at least one of the components being controllable independently of the other components. In addition, a method is disclosed for refilling the container of the minor component B of a dispensing tool.

Abstract: Needle guides are disclosed. An example needle guide includes a base; a housing configured to hold a container, the housing disposed on the base such that a longitudinal axis of the container is held at a first angle to vertical; and a syringe holder configured to guide insertion of a needle of a syringe into the container, the syringe holder disposed on the housing such that the syringe is inserted into the container at a second angle to the longitudinal axis of the container.

Abstract: An anesthetic cartridge is adapted to receive a volume of buffer by displacing a plunger in one end of the anesthetic cartridge inwardly so that addition of the buffer volume will not displace the plunger excessively beyond the end of the cartridge body. By properly determining the amount of buffer volume required to raise the pH of the anesthetic to a target value, the degree of inward displacement of the plunger can be determined and the cartridge can be used with a system for delivering a precise amount of buffer solution having a known pH into the cartridge to raise its pH, just before the anesthetic is delivered to the patient.

Abstract: A method is described for managing vapors generated from an ammonia-containing reductant delivery system. The method may include generating ammonia vapors in a first storage device and storing said generated ammonia vapors in a second storage device. Further, the method may include purging the stored vapors from the second storage device to upstream of a combustion chamber of the engine during a first condition and downstream of the combustion chamber during a second condition.

Abstract: Medical device assemblies capable of aspirating liquid into a syringe barrel or other medical devices while evacuating any air from the syringe are described. An exemplary medical device includes a syringe barrel, plunger rod and stopper assembly having an air permeable and liquid impermeable porous portion and structure for forming a vacuum within either the stopper or the plunger rod. Described is a medical device including a syringe barrel, plunger rod and stopper assembly having an air permeable and liquid impermeable porous portion and structure for forming a vacuum within chamber between the stopper and plunger rod wherein the plunger rod includes a sealing edge and is moveable relative to the stopper. Exemplary medical devices may include a vent for allowing air that permeates through the porous portion to escape to atmosphere. Methods for aspirating a syringe barrel with a liquid are also provided.

Abstract: Medical device assemblies capable of aspirating liquid into a syringe barrel or other medical devices while evacuating any air from the syringe are described. An exemplary medical device includes a syringe barrel, plunger rod and stopper assembly having an air permeable and liquid impermeable porous portion and structure for forming a vacuum within either the stopper or the plunger rod. Described is a medical device including a syringe barrel, plunger rod and stopper assembly having an air permeable and liquid impermeable porous portion and structure for forming a vacuum within chamber between the stopper and plunger rod wherein the plunger rod includes a sealing edge and is moveable relative to the stopper. Exemplary medical devices may include a vent for allowing air that permeates through the porous portion to escape to atmosphere. Methods for aspirating a syringe barrel with a liquid are also provided.

Abstract: Medical device assemblies capable of aspirating liquid into a syringe barrel or other medical devices while evacuating any air from the syringe are described. An exemplary medical device includes a syringe barrel, plunger rod and stopper assembly having an air permeable and liquid impermeable porous portion and structure for forming a vacuum within either the stopper or the plunger rod. Described is a medical device including a syringe barrel, plunger rod and stopper assembly having an air permeable and liquid impermeable porous portion and structure for forming a vacuum within chamber between the stopper and plunger rod wherein the plunger rod includes a sealing edge and is moveable relative to the stopper. Exemplary medical devices may include a vent for allowing air that permeates through the porous portion to escape to atmosphere. Methods for aspirating a syringe barrel with a liquid are also provided.

Abstract: A spray can product capable of preventing leakage where used or stored in a tilted or an inverted position, and keeping good safety and liquid retention even where a flammable liquefied gas is used. The spray can product is formed by filling a spray can having an ejection opening with a liquefied gas and an absorbing body for retaining liquid, and the absorbing body is composed of an assembly of cellulose fibers containing at least 45 mass % of fine cellulose fibers having a fiber length of 0.35 mm or less. The absorbing body compressed into a block-shaped configuration corresponding to that of the spray can is accommodated within the spray can while defining a space on the side of an ejection opening, and a lid-like member is provided between the space and the absorbing body to protect a surface of the absorbing body in a gas permeable manner.

Abstract: The invention relates to a method and a device for the sterile filling of a disposable injector with a defined dose of an injection solution, wherein the disposable injector comprises a cylinder/piston unit with a cylinder and with a piston that can be pulled back manually. The defined dose of the injection solution is stored in an interior of a container of a needle syringe held in a bored stopper. The cylinder interior is connected to the container interior in a gas-tight and liquid-tight manner through the bored stopper. The cylinder/piston unit is filled by pulling back the piston or by pressing the needle syringe piston. With the present invention, a method and a device for filling a disposable injector are developed in which, without intermediate weighing or risk of inaccurate readings, the disposable injector can be filled with a defined dose of an injection solution from a syringe with a fused-in needle.

Abstract: A liquid additive reservoir including a rigid casing delimiting a housing, and a fluid-tight flexible pouch mounted inside the housing of the casing and intended to contain the liquid additive, the flexible pouch being designed to be connected to the exhaust line of an internal combustion engine of a vehicle.

Abstract: Apparatus for dispensing a defined amount of dry powder concurrently to a plurality of spaced apart dose receiving containers include: (a) a dosing head comprising a support body with a plurality of spaced apart elongate channels having a channel length with an upper end defining an entry orifice and a lower end defining an exit port; (b) a dry powder bed residing above and in communication with the dosing head; and (c) at least one vibration source in communication with the dosing head channels configured to controllably apply a vibration flow signal, wherein, when the vibration flow signal is applied to the dosing head channels, dry powder from the dry powder bed flows through the elongate channels and out the exit port and when the flow signal is removed, dry powder does not flow through the dosing head elongate channels.

Abstract: The invention relates to microfluidic systems, and more specifically to a microfluidic system comprising a capillary channel (14) and an inlet (12) for receiving a fluid, as well as a method of filling a capillary channel (14). Provided is a microfluidic system, having an inlet (12) for receiving a fluid, a capillary channel (14), an outlet (20) for letting excess fluid out, and a reservoir (10) for interfacing the inlet (12) to the capillary channel (14). The reservoir (10) forms a first passage from the inlet (12) to the outlet (20), and a second passage from the inlet (12) to an entrance (22) of the capillary channel (14). A hydraulic resistance of the first passage is sufficiently low in order to effect a pressure reduction at the entrance (22) of the capillary channel (14) when a fluid is received under pressure at the inlet (12).

Abstract: A system for delivery of a beneficial agent in the form of a viscous liquid or paste allows holes in a medical device to be loaded in a single step process. The loading of a beneficial agent in a paste form also provides the ability to deliver large and potentially sensitive molecules including proteins, enzymes, antibodies, antisense, ribozymes, gene/vector constructs, and cells including endothelial cells.

Abstract: Provided herein is a single dose disposable pharmaceutical delivery apparatus and methods of use and manufacture thereof. One aspect provides a single dose disposable pharmaceutical delivery apparatus that includes a needle hub seal attached to a needle hub and a bladder that can contain a pharmaceutical composition. Another aspect provides for dispensing a pharmaceutical composition from the delivery apparatus by rupturing the needle hub seal and fluidically connecting the needle and the bladder. Another aspect provides manufacturing the delivery apparatus according to steps including attaching a needle hub and a needle hub seal and combining the bladder and the needle hub, thereby forming an apparatus described herein.