Abstract: Embodiments of the present disclosure include a cap for a container that incorporates a receptacle for an additive. The cap can enable separate transport of additives for the contents of the container in a sterile and convenient manner that enables mixing according to a user's preferences before the opening of the container and dispensing. According to some aspects, the configurable package can include pre-perforated portions to facilitate or allow a user to controllably mix and/or dispense additives onto the contents of the container. In some embodiments, an adaptor can be used to incorporate the described cap with existing bag or rigid disposable containers.

Abstract: An apparatus for facilitating dispensing payloads into a container. The apparatus is couplable with an opening of the container and includes a placing element and a dispensing element. The placing element is coupled with the opening, includes first openings fluidly coupled with the opening, and defines payload receptacles around the first openings. The payload receptacles define recesses for receiving payload holders. The payload holders include breakable layers for releasably securing the payloads into the payload holders. The dispensing element is coupled with the placing element, transitions from a first position to a second position based on an external action, and includes a pressing element. The pressing element presses the payload holders based on the transitioning for breaking the breakable layers and releasing the payloads from the payload holders. The payloads pass through the first openings for dispensing the payloads into the container based on the releasing.

Abstract: A reagent preparation assembly includes a body and a reaction chamber adjacent the body, the reaction chamber includes a reagent therein, such as a lyophilized reagent. An access port extends into the reaction chamber, and the access port is configured to receive an instrument. A seal extends across a portion of the reaction chamber and the access port. A reconstitution assembly is movably coupled with the body. The reconstitution assembly includes a plunger, a syringe and a piston. The plunger is movably coupled with the body. The syringe is selectively engaged with the plunger. The syringe includes a solution reservoir containing a solution, and movement of the syringe pierces the seal. The piston is selectively engaged with the plunger, and the piston is movably coupled within the syringe. Movement of the piston pushes the solution into the reaction chamber.

Abstract: An assembly for dispensing a substance into a receptacle, the assembly including: a) a first portion connected to an opening of the receptacle; b) a chamber for containing the substance, the chamber being at least partly located within the first portion; c) a seal located below the chamber, the seal retaining the substance in the chamber; d) a removable stop member; and wherein removal of the stop member enables the chamber to be moved downwardly to cause the seal to open and release the substance into the receptacle.

Abstract: A unitary cap assembly for a conventional water bottle or container with integral components, and a cap body with a lower section that snaps, screws or twists onto the bottle neck. The cap body includes an upper section providing for fluid flow, and having an integral stem which acts as a dip stick and when attached protrudes into the bottle. The stem is secured to the upper cap body with “fingers” or radial arms to create voids that liquid passes through for drinking. A dissolvable substance or composition is formed and attached to the stem. The stem suspends the substance in the liquid. The soluble substances can be shaped as pellets, capsules, rectangles or others that are desired and dimensioned for insertion through the bottle neck.

Abstract: An individual beverage bottle, with added convenience features making the bottle easy to open, and provides features to customize, personalize, and/or share in a very hygienic manner and providing a mechanism to secure a cup to the bottle such that an otherwise ordinary cup adapts and screws onto existing beverage containers that can be used to share the beverage or just be able to drink from a cup rather than directly from the bottle wherein, existing bottles can be utilized with very little, if any, extra footprint and minimal retooling. A proprietary labeling system is adapted to the bottle and cup.

Abstract: The invention relates to a device for packaging at least a first and a second fluid comprising an arrangement consisting of a first container for containing a first fluid and a second container for containing a second fluid, wherein the first container is substantially in the form of a tube, preferably in the form of a tube, the first end of which is provided with a dispenser and the second end of which is designed to attach said second container to this second end and thus close said second end of the first container, wherein the second container is substantially in the form of a tube, preferably in the form of a tube, the first end of which is designed to be attached to the second end of the first container, said first end of the second container being closed by means of a tearable wall, and the second end of which is closed by means of a movable wall, said movable wall being designed to be displaced in the direction of said tearable wall to open said tearable wall and thus allow the first and second flu

Abstract: A dispensing closure system includes an upper closure portion and a lower closure portion including an axial flow conduit and a vent conduit. The upper closure portion is axially movable relative to lower closure portion between shipping and dispensing positions. A seal is disposed on the lower closure portion over the flow and vent conduits. A peripheral spacing strip is removably secured to the upper closure portion and engages with either the lower closure or the outside of the container to prevent movement. A piercing probe includes piercing elements in alignment with the flow and vent conduits for piercing the seal. In the shipping position, the piercing elements are spaced from the seal. However, when the spacing strip is removed and the upper closure portion is axially moved to the dispensing position, the piercing elements pierce the seal to open the flow conduit and the vent conduit.

Abstract: Proposed herein is a dispenser type beverage container including: a cartridge cover member having a cartridge insertion space into which a cartridge storing a target material to be mixed is inserted; a main body located below the cartridge cover member to contain the target material discharged from the cartridge in an inner space thereof; and a button member of which the inner face of the upper portion capable of doing a rectilinear motion is arranged to meet an end of the cartridge inserted into the cartridge cover member, so that the target material stored in the cartridge is discharged into the main body when the upper portion is pressed down by external pressure.

Abstract: A device for mixing and delivering a solution includes a tubular barrel that includes a first end, a second end, and interior compartment. A first plunger is positionable at the first end of the barrel, is moveable within the interior compartment of the barrel, and includes a spike protruding into the interior compartment, the spike having an end configured for piercing a membrane. A second plunger is positionable within the barrel, is also moveable within the interior compartment of the barrel, and has a pierceable membrane. The second plunger and the second end form a first area within the barrel for housing a first solution to be mixed and the first and second plungers form a second area within the barrel for housing a second solution to be mixed.

Abstract: A beverage ingredient pod for releasing beverage ingredients into a bottle to create a mixed beverage includes a liquid-ingredient chamber, a solid-ingredient chamber, a frangible membrane between and separating the liquid-ingredient chamber and the solid-ingredient chamber, and a rigid piercer that extends to a point toward the frangible membrane. Upon a force applied to the beverage ingredient pod, a portion of the pod collapses and drives the rigid piercer through the frangible membrane. This mixes contents of the liquid-ingredient chamber with contents of the solid-ingredient chamber and releases the mixed contents from the beverage ingredient pod into a bottle below that is filled with a liquid, creating a mixed beverage.

Abstract: A closure capsule for closing a container, comprising: —a stopper (2) applicable to the container and comprising a first perforable membrane (21); —a first cutter (31) of the first membrane, said first cutter (31) being movable between a start stroke position and an end stroke position; in the start stroke position of the first cutter (31), in combination with at least the first membrane (21), the first cutter (31) delimits a first tank (41) for containing a first substance; in the end stroke position of the first cutter (31) at least a part of the first membrane (21) being perforated to enable passage of the first substance from the first tank (41) to the container. The stopper (2) comprises at least a second perforable membrane (22).

Abstract: A drug mixing container is provided. The drug mixing container includes a container with an opening facing upward and a cover body. An inner peripheral wall of the container includes at least one piercing structure protruding toward the opening of the container. The cover body accommodates a drug and includes a sealing film for sealing the drug in the cover body. In use, when an opening of the cover body is coupled downward to the opening of the container, the sealing film is pierced and torn by the piercing structure to make the drug in the cover body flow into the container, thereby preventing hands of an operator from being stained with the drug.

Abstract: The prevent invention relates to an apparatus for receiving heterogeneous materials which is coupled to a hole part of a container in which a content such as liquid or the like is contained. The apparatus for receiving the heterogeneous materials includes a main body coupled and fixed to a hole part of a container and a receiving part having a storage space within the main body. In the inner storage space of the receiving part, a foldable connection part is disposed in an upper portion of the storage space and an opening part formed below the foldable connection part breaks a receiving part sealing part sealing a lower end of the receiving part to allow a content within the storage space of the receiving part to drop down into the container, thereby mixing the heterogeneous materials. Here, a foldable soft resin may be added to the foldable connection part.

Abstract: A connecting system for providing a fluidic connection, preferably between containers, wherein the connecting system has at least two connecting arrangements configured to provide the fluidic connection, namely a first connecting arrangement and a second connecting arrangement, each of which is fluidically sealed in an initial state, wherein the first connecting arrangement has, in particular, an opening region that is deformable outside the opening region and is configured such that deformation causes the first connecting arrangement to open in the opening region.

Abstract: A dispensing closure system includes an upper closure portion and a lower closure portion including an axial flow conduit and a vent conduit. The upper closure portion is axially movable relative to lower closure portion between shipping and dispensing positions. A seal is disposed on the lower closure portion over the flow and vent conduits. A peripheral spacing strip is removably secured to the upper closure portion and engages with either the lower closure or the outside of the container to prevent movement. A piercing probe includes piercing elements in alignment with the flow and vent conduits for piercing the seal. In the shipping position, the piercing elements are spaced from the seal. However, when the spacing strip is removed and the upper closure portion is axially moved to the dispensing position, the piercing elements pierce the seal to open the flow conduit and the vent conduit.

Abstract: An assembly, a disposable foil tank, and method for providing a liquid including a plurality of chemicals for vapor administration. The assembly comprising a disposable tank with a first end and a second end, a foil seal, and an airflow ring. The disposable tank includes a first tubular portion and a second tubular portion. The first tubular portion defines a liquid container and a liquid container aperture at the second end of the disposable tank. The second tubular portion defines an air passage and an air passage aperture at the second end of the disposable tank. The foil seal is applied to the second end of the disposable tank, and the foil seal seals the liquid container aperture and the air passage aperture. The airflow ring includes a piercing element, the piercing element operable to puncture the foil seal when the airflow ring is attached to the second end of the disposable tank.

Abstract: The disclosure relates to devices, solutions and methods for collecting and processing samples of bodily fluids containing cells (as well as embodiments for the collection, and processing and/or analysis of other fluids including toxic and/or hazardous substances/fluids). In addition, the disclosure relates generally to function genomic studies and to the isolation and preservation of cells from saliva and other bodily fluids (e.g., urine), for cellular analysis. With respect to devices for collection of bodily fluids, some embodiments include two mating bodies, a cap and a tube (for example), where, in some embodiments, the cap includes a closed interior space for holding a sample preservative solution and mates with the tube to constitute the (closed) sample collection device. Upon mating, the preservation solution flows into the closed interior space to preserve cells in the bodily fluid. The tube is configured to receive a donor sample of bodily fluid (e.g.

Abstract: A microelectromechanical device having a first substrate of semiconductor material and a second substrate of semiconductor material having a bonding recess delimited by projecting portions, monolithic therewith. The bonding recess forms a closed cavity with the first substrate. A bonding structure is arranged within the closed cavity and is bonded to the first and second substrates. A microelectromechanical structure is formed in a substrate chosen between the first and second substrates. The device is manufactured by forming the bonding recess in a first wafer; depositing a bonding mass in the bonding recess, the bonding mass having a greater depth than the bonding recess; and bonding the two wafers.

Abstract: A heat seal pouch includes a bag, a cylinder, a partition assembly, and an outer skeleton frame. The bag is configured to hold a provided liquid. The cylinder is configured to hold a provided powder. The partition assembly is between the bag and the cylinder. The partition assembly is operable to form an openable partition in a bottom of the cylinder for selectively separating the cylinder from the bag. The outer skeleton frame is configured to house and seal the bag, the cylinder and the partition assembly. Whereby the heat seal pouch is configured for storing, transporting and selectively mixing the provided powder with the provided liquid.

Abstract: A disposable ingredient-dispensing apparatus selectively dispenses one or more ingredients. The disposable ingredient-dispensing apparatus includes a substantially circular base member comprising multiple chambers circumferentially positioned along the base member, and a ring frame configured to be rotatable circumferentially along a surface of the base member. Each chamber is filled with the one or more ingredients, and is sealed with a diaphragm. The ring frame comprises a rupturing member positioned at a predefined section of the ring frame, and the ring frame is rotated to selectively align the rupturing member to enclose one of the chambers, and the rupturing member contacts the aligned chamber to rupture the diaphragm for selectively dispensing the ingredients.

Abstract: A closure device (210) for use on the neck (238) of a bottle comprises a cap member (236) having a side wall (237) adapted to be secured to the neck, a fluid chamber (260) fixed at its upper end to the cap member and having a bottom aperture (266) at its lower end, a housing (254) at least partially surrounding the fluid chamber and having a flange member (258) adapted to extend at least partially across the top of the container neck, and a plug member (264) fixed to the housing and sealingly engageable in the bottom aperture of the fluid chamber.

Abstract: A bone material dispensing apparatus for preparing, mixing, and dispensing bone material into a foldable container is provided. In some embodiments, the dispensing apparatus comprises a tray and a foldable container. The tray includes a mixing surface, a dispensing surface and a means to measure the amount of material to be dispensed. A kit including a tray, a foldable container, and a spatula are also provided. A method of using the dispensing apparatus to deliver the bone material to a bone defect is also provided.

Abstract: A liquid drink concentrate dispensing system is provided. It includes a concentrate storage container and a housing with a piercing device for providing a flow path for selective discharge of drink concentrate into a cup for diluting with water. The storage container includes a pump to effect selective discharge of the concentrate.

Abstract: Methods and devices for forming droplets are provided. In certain embodiments, the methods and devices form droplets having different diameters.

Abstract: An adapter having a female coupling configured to receive and establish a friction seal with a male coupling of an external device for inserting or extracting a liquid to or from a container, by applying a load to the male coupling after inserting it into the female coupling, the load being provided by the weight of a portion of the external device, the adapter being configured for insertion in a mouth of the container and secured therein using a stretchable membrane that fits snugly around the mouth of the container for obtaining a tight seal, the stretchable membrane having tabs for a user to grasp.

Abstract: Apparatuses related to a beverage system. The system includes a piercing apparatus that includes an inner ring composed of a rigid material and an outer ring composed of a flexible material that encompasses the inner ring. The outer ring has an upper portion disposed above the inner ring that has a greater range of motion than the outer ring that encompasses the inner ring. The piercing apparatus further includes a piercer composed of a rigid material that is connected to the inner ring by a plurality of arms that radially extend from the piercer to the inner ring. The plurality of arms define a plurality of openings between the arms. The outer ring includes a protrusion that circumferentially protrudes outward from an outer surface of the outer ring.

Abstract: A microelectromechanical device having a first substrate of semiconductor material and a second substrate of semiconductor material having a bonding recess delimited by projecting portions, monolithic therewith. The bonding recess forms a closed cavity with the first substrate. A bonding structure is arranged within the closed cavity and is bonded to the first and second substrates. A microelectromechanical structure is formed in a substrate chosen between the first and second substrates. The device is manufactured by forming the bonding recess in a first wafer; depositing a bonding mass in the bonding recess, the bonding mass having a greater depth than the bonding recess; and bonding the two wafers.

Abstract: A transdermal administration device packaged body includes a transdermal administration device including an administration member housed in a container, the administration member having at least one projection protruding from a first surface of a substrate, and an outer package which houses the transdermal administration device and has a bag form including a front component and a rear component. The front component is positioned on a first surface side of the substrate, the rear component is positioned on a second surface side opposite to the first surface side of the substrate, and the front component has an opening member configured to be pulled open to open the outer package.

Abstract: The invention relates to a container and to the use thereof. The container has a chamber with a base for receiving a mixture component and an adapter for fixing the chamber to a second container. The adapter is connected to the chamber via a first connector and has a second connector to connect to the second container. Additionally, the adapter forms a flow channel for the mixture component extending between the first and the second connector. The adapter also has a blade element in the flow channel comprising a blade facing the base of the chamber in order to open the base. The first connector allows the chamber to rotate relative to the adapter and to the blade, said blade designed to cut through the base of the chamber along the edge of the base while the chamber rotates.

Abstract: A dosage dispensing cap and container assembly and method of use are disclosed. The assembly includes a container defining an opening that leads to an interior space. A cap is removably affixed over the opening and defines a channel that leads to the interior space. The cap includes a puncturing structure positioned at a bottom region of the channel. A plunger is slidably disposed within the channel and includes a sleeve portion and a dosage product housed within the sleeve portion. The plunger slides within the channel between a first position in which the plunger is located in an upper region of the channel, and a second position in which the plunger is located in a lower region of the channel and the dosage product contacts the puncturing structure.

Abstract: A connector system for medical fluid administration has a female connection member, which can act as an access port for a container of medical fluid, and a male connection member, for accessing the container of medical fluid. The female connection member defines a sheath for receiving a portion of the male connection member and this sheath is spanned at one end by a septum, which acts to close the container of medical fluid. A lumen is defined through the male connection member to allow passage of fluid therethrough. The septum has a central region and a peripheral region, the central region being of substantially greater thickness than the peripheral region. The male connection member comprises means for rupturing the peripheral region of the septum when it is received in the female connection member to form a connection.

Abstract: The present invention relates to closure arrangements for liquid containers, particularly but not exclusively for drinks bottles. A closure arrangement (20) for a liquid container for a base liquid comprises a reservoir (24A, 24B) for an additive liquid (28A, 28B). The closure arrangement (20) comprises a passage (54) for flow of liquid from the base liquid container (11) to a user, the passage including a mixing space (26) for mixing the additive liquid from the reservoir and the base liquid. The present invention further relates to a liquid container assembly including a closure arrangement. The present invention further relates to an additive reservoir for use in a closure arrangement.

Abstract: A beverage container and cap assembly for selectively dispensing a first beverage or a powder into a second beverage, including: a beverage container and a cap assembly, wherein the cap assembly includes: a base member; a reservoir member; wherein the reservoir member includes a piercing member disposed therein having a first end that is coupled to a deformable first surface of the reservoir member and a second piercing end that is disposed adjacent to an opposed pierceable second surface of the reservoir member; and a cap structure disposed partially within the base member that is configured to be selectively depressed, thereby contacting the first end of the piercing member and biasing the second piercing end of the piercing member through the opposed pierceable second surface of the reservoir member, thereby allowing the first beverage or the powder to flow from the reservoir member into the beverage container.

Abstract: Injection devices for delivering pharmaceutical compositions into the eye are described. Some devices include a resistance component for controllably deploying an injection needle through the eye wall. The resistance component may be disposed on a removable injector attachment or on a portion of the injection device housing. Other devices may include a filter for the removal of air, infectious agents, and/or other particulate matter from the composition before the composition is injected into the eye. Related methods and systems comprising the devices are also described.

Abstract: The invention relates to a connector for a container with a spiking solution for individual adjustment of dialysis solutions and/or dialysis concentrates. The connector ensures a contamination-free introduction of the spiking solution into the container of the dialysis solution and/or of the dialysis concentrate and reliable labeling of same as soon as the original contents have been altered by adding a spiking solution.

Abstract: A combination includes a container having a connecting portion, and a fluid preparation device, in particular a dialysis machine. The fluid preparation device is configured for mounting and connecting the connecting portion of the container. The fluid preparation device includes at least one line in fluid communication with an interior of the container in the connected position of the container. The container is filled with a first medium, and includes a reservoir containing a second medium. The fluid preparation device includes a rod-shaped element for opening the reservoir so that the first medium and the second medium are mixed with each other.

Abstract: A dispensing capsule (2) comprises a capsule body (4) having a first end (6) and a second end (8); a first cavity (14) and a second cavity (16) with a dividing member (18) between them within the capsule body (4), both cavities having an opening at the first end of the capsule body; a peripheral wall (24) at the first end (6) of the capsule body (4); and a flexible seal (30) bonded to the peripheral wall at the first end and to the dividing member so as to seal the contents of the first and second cavities from each other. The seal (30) is bonded less strongly to the dividing member (18) than to the peripheral wall (24). On an increase of pressure within the two cavities, the bond between the seal (30) and the dividing member (18) will eventually break, permitting the contents of the first cavity (14) to at least partly mix with the contents of the second cavity (16) while the bond between the seal (30) and the peripheral wall (24) remains intact.

Abstract: A shaker bottle having a vessel for retaining a liquid volume, a lid for closing said vessel, a container for storing a powder supplement, and an accessory compartment for storing valuables. The container is releasably arranged to a lower surface of the lid. The vessel is foldable for providing a folded state of the shaker bottle during transportation. The container is received by the bottom of the vessel in the folded state, and thus the release of the container is locked. In an unfolded state the container is released for supply of the powder supplement to the liquid in the vessel, while the container is serving as a stirring device. A method for use of the shaker bottle is provided for securing a safe storing of powder supplements during transportation and for improving the functionality of a shaker bottle for every user with an active lifestyle.

Abstract: The disclosure relates to compounds and compositions for bone formation, fracture treatment, bone grafting, bone fusion, cartilage maintenance and repair, and methods related thereto. In certain embodiments, the disclosure relates to compositions comprising one or more compound(s) disclosed herein derivatives, or salt thereof, for use in bone growth processes. In a typical embodiment, a bone graft composition is implanted in a subject at a site of desired bone growth or enhancement. In certain embodiments, compounds disclosed herein are useful for managing obesity and diabetes or other metabolic syndromes by modulation of brown fat.

Abstract: Temperature regulation devices for heating food are disclosed. The temperature regulation device is configured to heat food held in a food pan positioned in a well of food service equipment. The temperature regulation device includes a module or housing and heating element, and is configurable in a variety of positions, orientations, locations, or configurations relative to the well and the food pans to accommodate a variety of sizes and configurations of food pans.

Abstract: The disclosure relates to containers and other shaped articles (e.g., trays and dishes) for containing articles such as food products (e.g., cuts of meat and poultry or liquid-sensitive electronic parts) in shaped articles such as. In one aspect, the container has a reservoir portion into which liquid can be sequestered. In another aspect, the container includes a thermoformable substrate, a liner, and a lidding material, the lidding and the liner defining a compartment for containing articles. The compartment can be detached from the substrate by detaching the liner from the substrate without necessarily rupturing the compartment. A substantial portion of the containers described herein can be recycled by separating the liner and/or lidding from the substrate. The disclosure also relates to methods of making thermoformed articles having multiple layers that does not rely on use of a coextruded or other composite thermoplastic-containing substrate.

Abstract: A fresh-keeping bottle includes a volumetric bottle having a bottle cap, a bottle body and a base. The upper end of the bottle body has a liquid squeezing outlet. The lower part of the bottle body is fixed with the base that includes a flexible bottle bottom and a cylindrical support. The upper edge of the bottle bottom is fixed in the inner wall of the cylindrical support. The liquid can be squeezed from the fresh-keeping bottle by pressing with a single hand without leakage. Solid and liquid materials can be separately packed at the upper and lower parts of a package bottle through tinfoil, which is punctured through sharp protrusion of the bottle bottom to mix the solid and liquid materials. The bottle keeps the powder fresh in transmission and storage and can simply mix the solid and liquid material together without needing special work when in use.

Abstract: A cap for making a beverage in a threaded bottle includes an inner cap, an outer cap and a flavor container. The inner cap has external threads and internal threads that match the threads of the mouth of the bottle, and the outer cap has internal threads that match the external threads of the inner cap. The cap includes a first releaser for opening the flavor container into the bottle when the cap is being screwed onto the mouth of the bottle. The cap further includes a carbon dioxide container and a second releaser for opening the carbon dioxide container into the bottle when the outer cap and the inner cap are being screwed relative to each other. The disclosed embodiments also relate to a method for making a beverage.

Abstract: A beverage container includes a hollow container with a first reservoir and a second reservoir positioned within the hollow container, the first reservoir configured to store an aqueous beverage, the second reservoir sealingly storing one or more polymer matrices that include cannabinoid compounds, the second reservoir being configured to release the one or more polymer matrices into the aqueous beverage subsequent to the second reservoir being opened, the hollow container defining an opening through which a liquid in the hollow container is allowed to egress from the hollow container. The beverage container also includes a closure sealingly and operably coupled with the opening of the hollow container, the closure operably coupled with the second reservoir such that opening of the closure initiates opening of the second reservoir, the closure sealing the opening of the hollow container. Methods of using the beverage container and preparing a beverage containing cannabinoids are also described.

Abstract: A tissue-sample container assembly including a container defining a cavity configured to store a tissue sample and a lid connectable to the container to close the cavity. The lid has a receptacle adapted to contain a preserving agent, a seal forming at least a portion of a bottom of the receptacle, and a puncturing member arranged above the seal and actuatable to break the seal. A preserving agent is disposed in the receptacle.

Abstract: The apparatuses described herein provide a portable, pod-based beverage maker, such as an apparatus that makes smoothies and other similar beverages from pod-based ingredient mixtures. The apparatus provides an easy and simple way to combine ingredients in pods with water, ice, and other mixing liquids.

Abstract: A display package for two component cyanoacrylate compositions. The display package includes a stain-free transparent secondary package that enables visual inspection of a syringe-based primary package containing a bulk product that has volatile constituents such as a common cyanoacrylate adhesive.

Abstract: The metering device includes a metering container which can be fitted with screwing action on a standard bottle neck. The metering container has a funnel-shaped base, which is adjoined by a cylindrical lateral wall having, at the upper end, a cross-sectionally u-shaped collar, to which a cover surface can be applied in a form-fitting manner. At the top of the metering device is a pressure-exerting head with an encircling, detachable periphery. A puncturing mechanism having a two-part pressure-exerting pin can be actuated by the pressure-exerting head. The puncturing mechanism is fixed to the cover surface, prior to initial use, and is separated out of the cover surface by a cylindrical casing wall on the pressure-exerting head. The second part of the puncturing mechanism has a punching sleeve, which severs membranes which close the metering container, whereupon the contents of the metering container can be supplied into the bottle.

Abstract: Various embodiments of systems/methods relating to mixing of a plurality of substances are disclosed. Applications in medicine and in the pharmaceutical industry may be based on one or more of the systems/methods disclosed herein, providing mixing of first and second substances, as necessary, only a short time prior to dispensing thereof and/or in accordance with predetermined amounts of the first and second substances. Applications in the beverage industry may also be based upon various systems/methods disclosed herein, providing alcoholic and/or non-alcoholic mixing of a plurality of substances, as desired, a short time prior to dispensing and consuming and/or in accordance with precisely measured predetermined amounts, maximizing taste and enjoyment for the consumer.