Abstract: Formulations (e.g., solutions) comprising one or more water-soluble polymer(s), liposomes, and an aqueous carrier, are provided. The provided solutions are useful for rinsing, and/or immersing therein, a contact lens and/or in the treatment of ocular discomfort, for example, an ocular discomfort associated with a contact lens. Also provided are kits comprising the solution and a contact lens; articles-of-manufacturing comprising the solution and configured for dispending the solution; and methods utilizing the solution.

Abstract: A blister package for a contact lens is provided. A deformable slider supporting a lens is movable via pull-tab or hinge to lift the contact lens out of a lens well. The deformable slider can include a hinge connected to a flexible peel-away top of the blister package or connected to a pull tab that can be pulled to pull taut the deformable slider. A blister package is also provided that includes a hinged shell having a lateral opening opposite the hinge, and a deformable slider that is folded over onto itself and seals both a top chamber and a bottom chamber. By pulling a tongue of the deformable slider, which extends from the lateral opening, the deformable slider can be removed from the closed shell and the closed shell can be opened enabling access to the contact lens.

Abstract: A disposable packaging for at least one contact lens. The disposable packaging has at least one molded structure which forms at least one product cavity for accommodating the contact lens. The molded structure has at least one cleaning chamber having a cleaning system for cleaning and/or disinfecting fingers. The cleaning system includes a cleaning pad which absorbs and holds cleaning and/or disinfecting agent, the cleaning pad being fixed in the cleaning chamber and the surface of said pad being exposed when the cleaning chamber is opened.

Abstract: A storage/delivery device includes a first wall defining a well configured to receive a corneal tissue. The storage/delivery device includes a second wall configured to be positioned over the first wall and to seal the well. The second wall includes a recess configured to extend into the well to define a chamber between the first wall and the second wall. The chamber is configured to hold the corneal tissue when the second wall seals the well. A system may include the storage/delivery device above and a measurement system configured to measure the corneal tissue disposed in the well. In one example embodiment, the measurement system is an optical coherence tomography (OCT) system. In another example embodiment, the measurement system is a second-harmonic generation (SHG) or third-harmonic generation (THG) microscopy system.

Abstract: A cleaning device for a pair of spectacles, comprising a housing defining a cleaning space, a mounting part for holding the pair of spectacles inside said space, sets of opposing cleaning elements for cleaning opposing faces of glasses of the pair of spectacles, and a drive unit for moving the pair of spectacles and the cleaning elements relative to each other during a cleaning operation. The sets of opposing cleaning elements are positionable relative to each other between an inactive position, that is configured to have at least one of the sets of the cleaning elements lie spaced from at least one of the opposing faces of the respective glasses, and a cleaning position, that is configured to have the sets of opposing cleaning elements lie against both opposing faces of the respective glasses.

Abstract: A contact lens case includes a platform portion. The platform portion can include a receiving body, an inner wall formed in the receiving body, a floor connected to the inner wall, the inner wall and the floor defining a chamber, and a lens positioning guide formed in the floor of the chamber.

Abstract: Various examples of methods and systems are provided for increasing productivity of one or more photosynthetic cultures via self-powered energy output systems. In one example, a system includes a waterproof casing and an energy output module enclosed within the waterproof casing. The waterproof casing is configured to be neutrally buoyant in an enclosure comprising the one or more photosynthetic cultures. In another example, a method includes placing a self-powered energy output system within an enclosure, the self-powered energy output system being neutrally buoyant within the enclosure. The method further includes causing turbulence within the enclosure, and the self-powered energy output system harvests energy to power the self-powered energy output system via the turbulence within the enclosure.

Abstract: An intraocular lens (IOL) injectors and associated methods are described. The IOL injectors may include a collapsible portion configured to reduce the length of the IOL injector when the collapsible portion is altered from an uncollapsed configuration to a collapsed configuration. In some instances, an IOL may be advanced from a storage location to a dwell location when the collapsible portion is altered from the uncollapsed configuration to the collapsed configuration. The IOL injectors may also include a combination push and screw drive.

Abstract: The present disclosure proposes a contact lens package. The contact lens package includes a first substrate, a contact lens, and a guard ring. The contact lens is disposed on the first substrate. The guard ring is disposed on the first substrate and surrounds the contact lens, wherein the guard ring is fixed on a side surface of the first substrate. The contact lens and the guard ring are surrounded and sealed in the first substrate.

Abstract: A blister package for a contact lens is provided and has a body and a seal. The body includes a handle and a deformable bowl. The seal seals the deformable bowl at a bowl top opening. The handle includes a lateral portion and an end portion. The end portion curves downwardly to a distal end that terminates at a plane. The bowl is recessed from a top surface of the body and the outer bottom surface of the bowl is arranged substantially on the same plane as the distal end of the handle. The design provides leverage in holding the blister package while a user deforms and inverts the bowl into a dome, presenting a contact lens on top of the dome in position for direct transfer to a person's finger or for application directly on an eye without the need for any finger contact.

Abstract: A contact lens package includes a multi-layer laminate substrate and a cover sheet. The multi-layer laminate substrate includes a first polymer layer, a first metal layer and at least one pre-formed lens receiving portion that is sized to hold at least a portion of a contact lens. The cover sheet is removably secured to the substrate and configured to seal a contact lens within the at least one lens receiving portion. The substrate has sufficient structural integrity to maintain a shape of the lens receiving portion.

Abstract: A method of corneal and scleral inlay crosslinking and preservation is disclosed herein. The method includes cross-linking at least a portion of a donor cornea or a donor sclera so as to kill cellular elements in the portion of the donor cornea or the donor sclera, and make the portion of the donor cornea or the donor sclera less antigenic to a body portion of a recipient patient in which the portion of the donor cornea or the donor sclera is to be implanted; and storing the cross-linked donor cornea or the donor sclera for a long period of time prior to implanting the portion of the donor cornea or the donor sclera into the body portion of the recipient patient.

Abstract: A contact lens blister package 1 includes (i) a cavity 4 for storing a contact lens 20 and (ii) charging circuitry 3 configured to charge an electronic device 22 forming part of a contact lens 20 stored in said cavity 4. Related methods are also described.

Abstract: A cleaning apparatus holder assembly is described herein comprising in one example: a mounting pad configured to be attached to a work surface of a sink; the mounting pad comprising a first pivot component having a first axis of rotation; a swivel removably mounted to the mounting pad at the first pivot component and configured to rotate relative to the mounting pad about the first axis of rotation; the swivel comprising a second pivot component having a second axis of rotation not parallel to the first axis of rotation; and a resting arm mounted to the swivel at the second pivot component, configured to rotate relative to the swivel about the second axis of rotation; the second axis of rotation defining a lifting plane orthogonal to the second axis of rotation.

Abstract: A contact lens case is disclosed. The contact lens case has a fluid tank that stores fluid (e.g., contact lens solution, water, etc.). The contact lens case also has two lens assemblies (e.g., a first lens assembly and a second lens assembly), wherein each lens assembly has a lens reservoir that stores a contact lens. Further, each lens assembly has a pressure pump that upon actuation, draws fluid from the fluid tank, through a suction line and a one-way valve, to the corresponding lens reservoir.

Abstract: A blister package for a contact lens is provided. A deformable slider supporting a lens is movable via pull-tab or hinge to lift the contact lens out of a lens well. The deformable slider can include a hinge connected to a flexible peel-away top of the blister package or connected to a pull tab that can be pulled to pull taut the deformable slider. A blister package is also provided that includes a hinged shell having a lateral opening opposite the hinge, and a deformable slider that is folded over onto itself and seals both a top chamber and a bottom chamber. By pulling a tongue of the deformable slider, which extends from the lateral opening, the deformable slider can be removed from the closed shell and the closed shell can be opened enabling access to the contact lens.

Abstract: The embodiments provide a container (40) of the type to hold fresh food or produce. Container (40) has a base (42) and a lid (44) moveable with respect to the base (42) between an open position and a closed position. The lid (44) has a planar area (54). The base has a second planar area (56). In the closed position, the first planar (54) and the second planar area (56) include a substantially flat area suitable for receipt of an adhesive membrane, such as a self-adhesive label. The substantially flat area includes an edge (55) of the first planar area (54) and at least part of the second planar area (56).

Abstract: A device and method for preserving corneal graft tissue. In one embodiment, a device for preserving corneal graft tissue comprises: a first chamber; a second chamber; and a corneal graft tissue suspension assembly that is configured to retain and suspend the corneal graft tissue between the first chamber and the second chamber, the first chamber being fluidly isolated from the second chamber when the corneal graft tissue is graft tissue is retained and suspended within the corneal graft tissue suspension assembly. In one embodiment, a method includes filling a first chamber of a device with a first preservation medium and filling a second chamber of the device with a second preservation medium different than or the same as the first, a corneal graft tissue being located between the first and second chambers.

Abstract: A cartridge of an intraocular lens inserter comprises an insertion nozzle, having a distal insertion channel; an intra-ocular lens (IOL)-folding stage, to receive and to fold an IOL, proximal to the insertion nozzle, and having a proximal insertion channel; and an IOL-guiding structure. The IOL-guiding structure can include a first proximal guiding groove, or a first proximal guiding rib, or both, formed in the IOL-folding stage. An intraocular lens inserter comprises an inserter cylinder; a push-rod, partially in the inserter cylinder; a cartridge-receiving insertion end, to receive a cartridge that includes an insertion nozzle, having a distal insertion channel; an IOL-folding stage, proximal to the insertion nozzle, having a proximal insertion channel; and an IOL-guiding structure.

Abstract: A delivery system for an ocular implant includes a delivery tube having a delivery end with an opening and a control end. A delivery device fits at least partially within the delivery tube. The delivery device is configured to contact the ocular implant and control the position of the ocular implant within the delivery tube. The delivery system includes a fluid inlet nozzle that injects fluid into the delivery tube between the control end and the ocular implant. The injected fluid flows around the sides of the ocular implant and out from the delivery end of the delivery tube.

Abstract: The present invention relates to systems and methods involving interconnected plate components, including bases, lids and covers, interconnected in a manner such that a continuous strip of each component is prepared. The continuous strips may be stored as rollstock in a reel style. The physical properties of each continuous strip allow the base, lid and/or cover to include means for positive control. In one embodiment, the continuous strip of bases is advanced and processed through an automated system with positive control, and remains in the form of a continuous strip until agar in the bases is cured, at which time the bases are singulated. When a lid is applied to a base using methods described herein, an airtight seal is formed improving the quality of culture media used in testing.

Abstract: An eye-mountable device includes a hydrogel material. By drying the hydrogel material of the eye-mountable device, ethylene oxide may be used to sterilize the eye-mountable device. Such a sterilization method can be employed to sterilize the eye-mountable device when the eye-mountable device includes electronics, sensors, actuated lenses, or other components that may be damaged by heat, pressure, radiation, or other conditions used for sterilization. The eye-mountable device may be stored, dry, within a sealed sterile volume of a packaging material. The packaging material may be permeable to ethylene oxide such that the dried eye-mountable device may be sterilized by ethylene oxide after being sealed within the packaging material. The eye-mountable device could take the form of a contact lens, the form of a device configured to be placed against a sclera of an eye beneath an eyelid of the eye, or could take some other form.

Abstract: A clamshell package includes a base section having a triangular shape and first and second storage sections pivotally attached to the base section by first and second hinges, respectively. The storage sections have storage section flanges extending outward and terminating at storage section flange outer edges defining an outer perimeter of the clamshell package. When the storage sections are closed, the storage section flanges face and engage out to the storage section flange outer edges.

Abstract: An eye-mountable device, having an anterior convex side and a posterior concave side, is packaged in a container having a base and a wall. The wall extends from the base and defines an opening of the container. Disposed within the container is a pedestal, which has a first end attached to the base of the container and a second end opposite the first end. The eye-mountable device is mounted on the pedestal such that the posterior concave side contacts the second end of the pedestal and the eye-mountable device is elevated from the base of the container. The opening of the container can be sealed by a lidstock.

Abstract: The present invention relates to a contact lens packaging container. According to an embodiment of the present invention, an edge protection portion configured such that the peripheral zone of a contact lens is supported thereon in order to prevent the efficacy of the contact lens from being damaged and an optical zone protection portion configured such that the optical zone of the contact lens is supported in the state of having been pressed are formed on each accommodation portion of a body, thereby providing the advantageous effect of enabling contact lenses to be efficiently packaged in a narrow space and thus minimizing the size of the contact lens packaging container.

Abstract: A system for releasing a contained volume of gas. The system has a base with a pressure-release vent positioned within a flex region and a seal to disengagably seal the pressure-release vent. The seal has a gas vent path that extends from the pressure-release vent. The contained volume of gas passes through the gas vent path to apply force against the flex region and disengage the seal from the pressure-release vent, allowing the gas to exit through the pressure-release vent.

Abstract: A device for the storage of a corneal specimen has means for the reception and entrapment of a corneal specimen, connected to the means for the creation of a pressure gradient with overpressure on the endothelial side and to the preservation medium circulation means in the layouts that present the means for the reception and entrapment of the cornea specimen. The means for the reception and entrapment of the corneal specimen entrap the sclera ciliary zone surrounding the cornea in an airtight manner to delimit a separate endothelial chamber and epithelial chamber in which the preservation medium can circulate with an overpressure in the endothelial chamber; The intermediate component and the endothelial lid comprise inlet and outlet orifices for the preservation medium which are connected to the means for the circulation of the preservation medium and the creation of a pressure gradient between the endothelial chamber and the epithelial chamber with overpressure in the endothelial chamber.

Abstract: Various systems and techniques for inserting an intraocular lens are disclosed. In particular implementations, a system and a technique for inserting an intraocular lens may include the ability to move, in response to a force being applied in a first direction along a longitudinal axis, a first plunger tip along the longitudinal axis and into a delivery cartridge to fold an intraocular lens and move in a second direction along the longitudinal axis in response to the applied force being reduced. The system and the technique may also include the ability to engage a second plunger tip and move, in response to a force being applied in the first direction along the longitudinal axis, the second plunger tip along the longitudinal axis and into the delivery cartridge to insert the intraocular lens.

Abstract: The packages described by this invention all have reduced “head space,” that is, the distance from lid to lens. Packages contain dimples to achieve this reduced head space. Specifically, packages are designed with dimple sag equal to or less than 1.90-mm, or volume displaced equal to or less than 360 ?l. Combined with the existing primary packaging, it has been found that such conditions provide for reduction in folded lens rate during shipping and handling. As well, lenses stored or having an extended time in low head space packages in a “foil down” orientation now have characteristics closer lenses stored in a “foil up orientation”.

Abstract: Ophthalmic devices and methods of treating allergic conjunctivitis are disclosed herein.

Abstract: Corneal implant applicator devices and methods of using. In some embodiments they include an implant applicator and an implant support, wherein the implant applicator and implant support are disposed relative to one another to form an implant nest that is adapted to house a corneal implant; wherein the applicator has a greater affinity for the corneal implant than the support.

Abstract: Ophthalmic devices and methods of treating allergic conjunctivitis are disclosed herein.

Abstract: The present invention provides a pill tray that allows a user to efficiently and reliably verify the contents of a filled prescription. Design features that avoid the presence of sharp edges and allow visualization of the entire surface of the pill tray help reduce and/or eliminate the risk of commingling of pills between separate prescriptions.

Abstract: Disclosed herein are embodiments of a sighting device, and methods of making and using such a sighting device, whereby the sighting device comprises a chamber coupled to the sighting device; and a light-emitting element contained within the chamber; wherein the chamber contains only non-radioactive material; and wherein the light-emitting element emits a first amount of visible light to provide a viewable aiming indicium in low light conditions.

Abstract: Hydrogel contact lenses that are derived from a polymerizable composition including at least one hydrophilic monomer and at least one phosphine-containing component are described. The hydrogel of the contact lenses can be a silicone hydrogel or a non-silicone hydrogel. Use of polymerizable compositions comprising a phosphine-containing component can be cured under both inert and air atmospheres, and can be used to form hydrogel contact lenses having improved shape retention properties, having improved resistance to discoloration. Batches of hydrogel contact lenses and methods of making hydrogel contact lenses are also described.

Abstract: A container for a contact lens, having a micro-textured pattern on an interior surface thereof to prevent adherence of the lens to the container. In-container inspection of the lens within the container does not recognize the micro-textured pattern of the container as a defect on the lens.

Abstract: The packages described by this invention all have reduced “head space,” that is, the distance from lid to lens. Packages contain dimples to achieve this reduced head space. Specifically, packages are designed with dimple sag equal to or less than 1.90-mm, or volume displaced equal to or less than 360 ?l. Combined with the existing primary packaging, it has been found that such conditions provide for reduction in folded lens rate during shipping and handling. As well, lenses stored or having an extended time in low head space packages in a “foil down” orientation now have characteristics closer lenses stored in a “foil up orientation.

Abstract: A tool box includes a box with a base and a cover. A positioning member is located in the reception recess of the base and has multiple insertion holes. Each insertion hole is cooperated with a bit type indication which is light permeable. A back-light plate is located between the inside of the reception recess and the positioning member. A light source is located on one of sidewalls of the reception recess. The back-light plate changes paths of light beams generated from the light source toward the bit type indications so that the bit type indications are illuminated when the cover is opened.

Abstract: The present disclosure provides a contact lens package containing a contact lens in a compressed state. In one exemplary embodiment, the overall internal depth of the package is less than the natural sagittal depth of the contact lens. Different single-use contact lens package shapes and configurations may be used. In some embodiments, a spring disc is included in the packages to help present the contact lens to the user when the package is opened. The contact lens packages may be adhered or clipped to a card or other carrier sheet, and may be housed in a number of different secondary packages.

Abstract: Various systems and techniques for inserting an intraocular lens are disclosed. In particular implementations, a system and a technique for inserting an intraocular lens may include the ability to move, in response to a force being applied in a first direction along a longitudinal axis, a first plunger tip along the longitudinal axis and into a delivery cartridge to fold an intraocular lens and move in a second direction along the longitudinal axis in response to the applied force being reduced. The system and the technique may also include the ability to engage a second plunger tip and move, in response to a force being applied in the first direction along the longitudinal axis, the second plunger tip along the longitudinal axis and into the delivery cartridge to insert the intraocular lens.

Abstract: Providing a system which can exhibit a desired effect of improving hydrophilicity of a contact lens without causing adverse influences on sense of use of the contact lens and a cleaning effect, and which can effectively prevent adhesion of lipid stain. Also providing a packaging solution for the contact lens which can effectively suppress or prevent reduction of its viscosity with time even when the packaging solution is sterilized by heating. The contact lens is immersed in an aqueous solution which contains a low-molecular weight hyaluronic acid having a molecular weight of not higher than 80,000, or a salt or derivative thereof, and which has a pH of 6.0-8.0 and an osmotic pressure of 220-380 mOsm.

Abstract: The packages described by this invention all have reduced “head space,” that is, the distance from lid to lens. Packages contain dimples to achieve this reduced head space. Specifically, packages are designed with dimple sag equal to or less than 1.90-mm, or volume displaced equal to or less than 360 ?l. Combined with the existing primary packaging, it has been found that such conditions provide for reduction in folded lens rate during shipping and handling. As well, lenses stored or having an extended time in low head space packages in a “foil down” orientation now have characteristics closer lenses stored in a “foil up orientation.

Abstract: An IOL injector system includes an injector; a holder for holding an IOL; and a container for holding the holder. The injector has an injection channel and a plunger movable down the channel; and a holder receiving space for snappingly receiving the holder, and the holder has a channel part with a channel forming part of the injection channel of the injector when the holder is snapped into the receiving space of the injector in line with the injection channel, the IOL being provided in the channel of the holder when holding the IOL; and opposite openings for allowing the IOL to pass, allowing the plunger to urge the IOL out of the holder and through the injection channel. The container has a reservoir for holding a storage liquid and holder; closing walls for closing the opposite openings of the holder; and retaining parts for holding the holder.

Abstract: This invention provides a method of packaging and manufacturing a contact lens in a container, wherein the container comprises a central recess formed of a curved surface with a ring-shaped protruding portion surrounding the curved surface, the method comprising the steps of: providing the container; injecting a lens-forming monomer mixture into the central recess to form the contact lens along the curved surface of the central recess; combining the container and a hand-held section; pouring a solution into the container to immerse the contact lens in the container; and sealing the container with a lid for sealing the contact lens and the solution in the container; wherein the curved surface of the central recess has one or a plurality of continuous radii of curvature Rrecess less than a radius of curvature Rlens of the contact lens in its hydrous state.

Abstract: An improved method of cast molding contact lenses, wherein a lens forming mixture is cured in the lens-shaped cavity formed between molding surfaces of a male and female mold sections, wherein the improvement comprises at least one of sections is injection molded from a controlled rheology polypropylene.

Abstract: Methods, devices, and systems for moving wet ophthalmic lenses are described in which the ophthalmic lenses are first placed in wells of lens carriers and are centered by the structure of the wells. The carriers are then moved to a transfer module of a packaging system for transferring the ophthalmic lenses in blister packages. The transfer from the carriers to the blister packages are performed by a pick and place robot having pickup heads sized and configured for suctioning the ophthalmic lenses from the lens carriers.

Abstract: A mold assembly for manufacturing ophthalmic lenses which comprises an anti-tilt feature that prevent relative movement of one half of the mold assembly relative to the other half of the mold assembly. The anti-tilt feature ensures that the edges of the ophthalmic lenses are symmetric around their periphery.

Abstract: A contact lens case including a container main body provided with a housing recess for storing a contact lens and a liquid agent, and a lid that is connected to the container main body via a hinge in a freely openable and closable manner. A lens holding body is displaceably housed in the housing recess, and by connecting the lid and the lens holding body via a connecting member, the lens holding body can undergo rising and falling displacement following open and close action of the lid around the hinge. A displacement restricting member is provided that restricts a direction of the rising and falling displacement of the lens holding body to the vertical direction that coincides with a depth direction of the housing recess.

Abstract: A material is provided for contact lens including a first siloxane macromer represented by the following formula (I): wherein R1, R2 and R3 are independently C1-C12 hydroxyl group, C1-C12 alkyl groups or C1-C12 siloxane group; R4 is C1-C6 alkylene group or C1-C6 alkylene substituted with ether group; R5 is —H, —CH3, —CH(CH3)2, —CH(CH3)CH2(CH3), —CH2CH(CH3)2, —CH2C6H5, —CH2OH, —CH(OH)CH3, —CH2CONH2 or —CH2CH2CONH2: R6 is —NHCONH—, —NHCO—, —R8NHCONH— or —R8NHCO—, wherein R8 is —O—, —O(CH2)n— or —(CH2)n— and n is an integer of 1-10; R7 is hydrogen or methyl; and m is an integer of 10-100.

Abstract: Provided is a contact lens case of a novel structure that will effectively supplement the sterilization effect which was insufficient in the past with non-heating type disinfectant methods such as the MPS method and hydrogen peroxide method, making it possible to realize an effective sterilization process on soft contact lenses. In a storage solution with a sterilizing action, a slanted loading member is provided, wherein a convex spherical lens loading surface is formed from an antimicrobial material and a contact lens is held in a slanted state such that a geometric center of the contact lens loaded on the lens loading surface is located at a position separated from a top of the lens loading surface.