Abstract: A daily blister card housing a unit dose includes a back side and a front side opposite the back side. The front side includes a manufacturer indicator visible on the front side. A face has an outer periphery and a total planar area bounded by the outer periphery. One or more blisters extend outwardly at the face that contains at least three unit doses that are visible from outside the one or more blisters. Each of the one or more blisters includes a shoulder contacting a cavity backing surface and a projected cavity area bounded by the shoulder that is projected onto the cavity backing surface. A total projected cavity area of the one or more blisters is no more than about 45 percent of the total planar area bounded by the outer periphery.

Abstract: A child-resistant blister package. The package has a top face, a bottom face, and a periphery. The package also has a protection layer with a top face, a bottom face and a periphery; a blister layer with one or more cavities; and an access layer with a top face, a bottom face, and a periphery. The bottom face of the access layer has a line of weakness that allows the unit dose to be removed from the cavity in one-step by applying a force to the top of the cavity and pressing the unit dose through the line of weakness. The bottom face of the protection layer and the top face of the access layer are permanently joined along substantially the entire periphery of the package. The blister package can also contain a tear resistant layer.

Abstract: A sealed container containing a foodstuff or beverage has a lid that includes a heat-sealable, composite film that includes a polymeric substrate layer having a first and second surface, a primer layer that includes PVdC disposed on the first surface, and a heat-sealable polymeric layer extrusion coated on the primer layer. The heat-sealable polymeric layer is 12 ?m thick or less and includes a copolymer having repeating monomeric units of ethylene and at least a second type of repeating monomeric unit having the formula [—CH2C(R1)(X)—] wherein: X is selected from —COOR2 and —OC(O)CH3; R1 =H or methyl; and R2 is H, C1-10 alkyl or a counterion M.

Abstract: An outer sleeve includes first and second opposed side panels edges, hinge panels interconnecting the first and second side panels such that at least one chamber is defined between the first and second side panels, at least one of the hinge panels being hingedly connected to at least one of the first and second side panels along one of the opposed side edges of the at least one side panel, and at least one inner panel positioned at least in part inside the at least one chamber. The at least one inner panel includes a slide card locking mechanism for releasably locking at least one slide card in a locked position within the at least one chamber. The at least one side panel includes a release button positioned proximate the slide card locking mechanism of the at least one inner panel. The at least one inner panel is hingedly connected to one of the end edges of the at least one panel.

Abstract: A packaged product assembly is provided. The packaged product assembly may include a tray slidably received in a dispensing container. The tray may be a blister pack including units of a product received in sealed cavities. A locking apparatus may be configured to releasably retain the tray in a locked configuration. The locking apparatus may include one or more locking protrusions that engage corresponding locking apertures in the tray. The locking apparatus may also include buttons positioned on opposing sides of the tray. When the buttons are depressed toward one another, the locking protrusions may move relative to the locking apertures such that the tray is unlocked and may be withdrawn from the dispensing container.

Abstract: A blister and package system made of a blister card and an outer package with unique interacting locking mechanisms. The blister card or strip is inserted into the outer package or sleeve and locks immediately without having to further process the outer package or the blister card or strip. The user is able to expose the blisters from the outer package by disengaging the lock. The blister card or strip includes a formable, pliable sheet material, into which one or more individual cavities or blisters are formed. The separated cavities are loaded with product and sealed with one or more layers of puncturable or tearable sheet material, such as aluminum foil. The blister card or strip contains a plastic rivet assembly that forms an interference mechanism. The rivet is trapped by an internally formed panel and stopped by a catch flap included in the outer package.

Abstract: The present invention relates to a titration package for providing at least one pharmaceutical composition in at least two different dosages. The titration package comprises at least two sets. Each set comprises at least three individually addressable regions. Each addressable region preferably comprises or is represented by a pharmaceutical composition, preferably a tablet. The dosage of the pharmaceutical composition is the same within each of the at least two sets (“common dosage”), while the dosages of the pharmaceutical compositions are different for one of the at least two sets compared to at least one other of the at least two sets. The arrangement of the at least two sets is not a matrix-like arrangement.

Abstract: A conveniently portable daily blister card including a front side and a back side opposite the front side. The front side includes a face having a width, a right side edge, a left side edge, a top edge, and an outer periphery. In addition, the front side includes at least three blisters extending outwardly at the face and a primary manufacturer indicia area. Each blister contains a unit dose. The back side includes regulatory information that remains on the back side when a unit dose is removed from a blister through the back side of the card.

Abstract: A method and capsular medication delivery and inhalation device is used with a medication capsule. The capsule is free-standing in a capsule chamber and not secured in a fixed position. The capsule is moved with a moveable back wall and other cooperative structure into an opener which releases the medication inside the capsule. The device may include an aerosol stream for facilitating medication delivery. The device works with capsules of varying sizes and shapes.

Abstract: A child-resistant medication container assembly and method of dispensing the medication from the container assembly. The medication container assembly includes a blister pack with a plurality of compartments, each of which supports a medication. The container also includes a puck and a box. The blister pack compartments are aligned with openings on the puck, and the box is configured to receive and secure the puck and the blister pack such that each of the plurality of compartments is aligned with a complementary opening in the box.

Abstract: The present invention is a novel, theft-resistant, and senior-friendly packaging for consumer and retail products that is cheap and easy to manufacture. The packaging is designed to prevent individuals from gaining access to the enclosed product through tampering with the packaging while at the same time meeting or exceeding federal child-resistant and senior-friendly guidelines. The packaging incorporates plastic material and multiple cuts to be tear-resistant and to halt the propagation of a tear, if one should occur.

Abstract: A method and compositions for treating a patient that prevent or reduce drug abuse and overdose events.

Abstract: A packaging for active substance-containing films. The packaging comprises a carrier layer and a covering layer connected releasably to the latter, has in a paired arrangement two opposite surface regions which are separated from one another by a web and within which the covering layer is not connected to the carrier layer. Two spaces are formed, separate from one another and enclosed on all sides, for receiving the films in pairs. Within the web, a further surface region is present, in which the carrier layer is not connected to the covering layer, with the result that a cavity enclosed on all sides is formed. At least one perforation line is present within the web.

Abstract: Adhesive tabs having individual apertures are adhered to individual miniature products to be dispensed. The products are supported on a product carrier component having passages through which the tabs individually pass. A hook component is movable relative to the product carrier component. The hook component has a hook sized to successively enter each aperture, and to successively catch and successively remove each tab from its individual product during relative movement of the components.

Abstract: The present invention relates to medicament blisters for powder inhalers. The blisters according to the invention contain an inhalable powder comprising a medicament. The blisters are characterized by a reduced permeability for water vapor, which is achieved by decreasing the height of the sealing lacquer layer.

Abstract: A packaged product assembly is provided. The packaged product assembly may include a packet received in a dispensing container. The packet may be a blister packet including units of a product received in sealed cavities. The dispensing container may include a top casing and a bottom casing. The upper casing may be pivotably connected to the lower casing such that the upper casing is moveable between a closed position in which access to the packet is substantially blocked, and an open position in which access to the packet is provided. The packet may be supported by a shoulder defined at an inner surface of sidewalls of the lower casing such that a receptacle is formed between the packet and a major wall of the lower casing. A unit of the product released from one of the sealed cavities may be received in the receptacle and dispensed via a dispensing aperture.

Abstract: There is provided a content use monitoring package and method of making the same. The package includes a cover layer followed by a blister card layer. The third layer comprises an electronic sensor monitoring tag connected to a rupturable layer imprinted with a conductive grid. The grid is printed on a non-conductive, non paperboard rupturable substrate and is aligned with associated blisters in the blister card. To ensure precise and reliable electrical continuity between the tag and grid they are connected by a low or zero insertion force flat flex connector which connection is also reversible. The tag includes re-usable electronic circuitry and power source. The fourth and bottom layer is a backing which contains a mechanism to tear open the package and remove the tag by unplugging the flex circuit connector. The tag can then be reused and the battery replaced as required.

Abstract: A blister and package system made of a blister card and an outer package with unique interacting locking mechanisms. The blister card or strip is inserted into the outer package or sleeve and locks immediately without having to further process the outer package or the blister card or strip. The user is able to expose the blisters from the outer package by disengaging the lock. The blister card or strip includes a formable, pliable sheet material, into which one or more individual cavities or blisters are formed. The separated cavities are loaded with product and sealed with one or more layers of puncturable or tearable sheet material, such as aluminum foil. The blister card or strip contains a plastic rivet assembly that forms an interference mechanism. The rivet is trapped by an internally formed panel and stopped by a catch flap included in the outer package.

Abstract: The present invention relates to a novel device for accommodating and storing blister packs, particularly pharmaceutical blisters, and for releasing a tablet or capsule from the blister pack using a means for punching the cover film of the blister.

Abstract: Described herein are pharmaceutical compositions for the delivery of poorly soluble active pharmaceutical ingredients. In particular, a substantially clear fexofenadine HCl solution in a soft gelatin capsule is described.

Abstract: A child-resistant blister package. The package has a top face, a bottom face, and a periphery. The package also has a protection layer with a top face, a bottom face and a periphery; a blister layer with one or more cavities; and an access layer with a top face, a bottom face, and a periphery. The bottom face of the access layer has a line of weakness that allows the unit dose to be removed from the cavity in one-step by applying a force to the top of the cavity and pressing the unit dose through the line of weakness. The bottom face of the protection layer and the top face of the access layer are permanently joined along substantially the entire periphery of the package. The blister package can also contain a tear resistant layer.

Abstract: A recyclable blister pack system is provided, including a substrate having a dry tack cohesive adhesive layer deposited on one of its surfaces and a blister layer for receiving a product. The properties of the dry tack cohesive are selected so the blister layer is separable from the substrate without leaving substantial substrate residue on the blister layer. This improves the recyclability of the blister layer.

Abstract: A packaging unit (13) comprises a blister unit (1) with cavities (5) forming receiving chambers (6) accommodating a fill material, particularly a pharmaceutical active substance formulation, and a support unit (7) that supports the blister unit (1) and is releasably attached thereto, of a size corresponding to the blister unit (1). The blister unit (1) has at least one locking opening (3) and the support unit (7) forms a support shell (12) that surrounds the blister unit (1) with a raised edge (8), at least one fastening element (10a, 10b) of said support shell (12) protruding from the base surface (9) thereof and engaging into the locking opening (3) and holding the blister unit (1) removably clamped in the support shell (12).

Abstract: A pharmaceutical product supply in the form of a container (e.g., secondary packaging) and a pharmaceutical product receiver (e.g., primary packaging) is disclosed. The pharmaceutical product receiver may include a plurality of pockets or receptacles, and may be disposed within the container. Pharmaceutical product may be enclosed within one or more of these receptacles. The pharmaceutical product receiver may be locked to at least some degree within the container to facilitate disposal of the pharmaceutical product supply, for instance at a time when some of the pharmaceutical product may have been removed from the pharmaceutical product receiver but prior to utilizing all of the pharmaceutical product originally provided with the pharmaceutical product receiver.

Abstract: A blister card with a back side and a front side opposite the back side. The front side has a plurality of blisters and each blister contains a unit dose and each unit dose contains an active. Each blister card contains from about 12 hours to about 24 hours of unit doses according to the dosage instructions. The actives can be the same or different.

Abstract: A system is provided for monitoring the removal of blister pack contents. An array of spatially-extended, electrically parallel breakable traces made from electrically resistive material is formed behind a corresponding array of blisters of a blister card. Then this array is connected in series with a reference resistor to form a voltage divider. All resistive traces are formed from the same materials in a single operation. Blister breakage is determined using changes in the ratio of the resistances of the array and the divider. A predictive algorithm is used to adjust the threshold resistance ratio change that signals blister breakage and voltage ratios are used to adjust for battery output changes over time. Breakage events and their time of occurrence are recorded in nonvolatile memory for later retrieval. Additional resistors can be used for activating the system and detecting tampering.

Abstract: A package for dispensing pills that is childproof yet senior-friendly. The package includes a housing, which may be substantially tear-resistant, that encloses one or more blisters. In one embodiment, the cavities of the blisters are positioned such that pills or other objects are dispensed into a chamber. An object dispensing opening associated with the chamber is selectively covered by a childproof closure member. In various embodiments, the childproof closure may be rotationally or slidingly connected to the package to move between a closed position and an open position to selectively permit dispensing of the objects.

Abstract: Tubes for storing unit doses of drugs are disclosed, the tubes may include an elongate outer casing having two open ends, an inner structure inside said casing, which includes two opposite symmetrical walls connected at the ends thereof and ribbed on the inner surfaces thereof such as to enable the insertion and fastening of a blister pack containing a unit dose of a drug in channels opposite to said walls, and a pulling means for inserting and extracting the inner structure from the outer casing. Devices and methods for filling the tube with unit doses of drugs is also disclosed, along with cabinets for dispensing unit doses of drugs from said storage tube.

Abstract: An oral pharmaceutical composition in unit dose form, each unit dose comprising a lipophilic drug substance within a unitary carrier body, said body comprising a soft, chewable, gelled oil-in-water emulsion.

Abstract: This invention provides a method of treating a subject afflicted with multiple sclerosis or presenting a clinically isolated syndrome comprising administering to the subject laquinimod as an add-on therapy to or in combination with fingolimod. This invention also provides a package and a pharmaceutical composition comprising laquinimod and fingolimod for treating a subject afflicted with multiple sclerosis or presenting a clinically isolated syndrome. This invention also provides laquinimod for use as an add-on therapy or in combination with fingolimod in treating a subject afflicted with multiple sclerosis or presenting a clinically isolated syndrome. This invention further provides use of laquinimod and fingolimod in the preparation of a combination for treating a subject afflicted with multiple sclerosis or presenting a clinically isolated syndrome.

Abstract: A package includes an outer container and an inner receptacle. The outer container forming a cavity for the inner receptacle having an open or openable end through which the inner receptacle can be inserted. The package includes a two-part locking mechanism for locking the inner receptacle within the cavity of the outer container. The outer container includes a first part of the two-part locking mechanism and the inner receptacle includes a second part of the two-part locking mechanism. The outer container includes at least one demarcated pressing zone, wherein the at least one demarcated pressing zone is configured and/or stylised and/or shaped and/or arranged to encourage a user to apply a force directed inwardly of the outer container toward the cavity for deactivating the locking mechanism to thereby release the inner receptacle for its withdrawal at least partially from the outer container.

Abstract: A containment system for packaging a plurality of products that are to be accessed in a predetermined sequence. The containment system includes a plurality of product compartments that each holds at least one of the plurality of products. Indicators having a gas reactive material that changes appearance after a predetermined period of time of exposure to ambient air are deployed when gas cover seals are removed or broken to access a product in the product compartment.

Abstract: A press-through package for articles such as medicines which can reliably prevent a recipient from accidentally swallowing the whole package without opening it, including solid medicines M stored in a plurality of pockets of a base sheet one by one and the pockets sealed by a cover film having attached to the rear surface of the base sheet, wherein the entire package of the press-through package is made in a cylindrical form which cannot allow a recipient from accidentally swallowing and from which the medicines can be taken out easily.

Abstract: A blister card with a back side and a front side opposite the back side. The front side has a plurality of blisters and each blister contains a unit dose and each unit dose contains an active. Each blister card contains from about 12 hours to about 24 hours of unit doses according to the dosage instructions. The actives can be the same or different.

Abstract: Embodiments of a blister sheet used to manage prescription pills are described herein and include a plurality of spaced-apart cavities, each surrounded by a flange on an open side of each cavity. The flanges together defining a top surface of the blister sheet. Two adjacent cavities are attached by adjacent sides of their respective flanges. Each of the adjacent sides having two longitudinal ends, each having a notch. When a sealing sheet is secured onto the top surface, the notches define unattached portions of the sealing sheet that can be used to grip onto the sealing sheet for its detachment from the top surface. The flanges of two adjacent individual blisters are joined by a tearing line that is weaker at the longitudinal ends thereof.

Abstract: A medicine packaging PTP sheet capable of protecting a pocket from pressurization by external force in a combined state in which the medicine packaging PTP sheet has a first sheet in which a pocket capable of accommodating a medicine and a projecting convex portion each are projected from the upper surface and a second sheet which is attached to the lower surface of the first sheet and blocks an opening of the pocket. A first distance L1 from the upper surface of the first sheet to the projection end of the convex portion is longer than a second distance L2 from the upper surface of the first sheet to the projection end of the pocket.

Abstract: A press-through package for articles such as medicines which can reliably prevent a recipient from accidentally swallowing the whole package without opening it, including solid medicines M stored in a plurality of pockets of a base sheet one by one and the pockets sealed by a cover film having attached to the rear surface of the base sheet, wherein the entire package of the press-through package is made in a cylindrical form which cannot allow a recipient from accidentally swallowing and from which the medicines can be taken out easily.

Abstract: A packaging structure for receiving at least one blister pack. The packaging structure includes at least one blister pack retainer for receiving and enclosing the blister pack, the blister pack retainer having a first side member, a second side member, a first end and a second end, the second end having at least one tab portion extending therefrom, and a slidable cover for enclosing the at least one blister pack retainer, the cover having a first end and a second end, the first end having at least one tab stop member extending therefrom, whereby when the at least one blister pack retainer is withdrawn from the slidable cover, the at least one tab stop member of the slidable cover and the at least one tab portion of the at least one blister pack retainer cooperate to restrain the at least one blister pack retainer from being fully withdrawn from the slidable cover. A method of making a packaging structure is also provided.

Abstract: The present invention relates to a security label for securing medications retained in an individual packaging, comprising a base layer (10, 20, 30) that can be adhesively bonded to the individual packaging (12, 22, 32), wherein at least one opening cut (17, 37, 47, 57, 67, 77, 87, 97, 107, 117, 127, 137, 147, 157) per medication (16) is provided in the base layer (10, 20, 30) in the area of the expected medications (16), wherein the opening cut (17, 37, 47, 57, 67, 77, 87, 97, 107, 117, 127, 137, 147, 157) has at least one first and one second partial cut, and wherein the first partial cut and the second partial cut meet or cross, wherein two, three, four, or five opening cuts (17, 37, 47, 57, 67, 77, 87, 97, 107, 117, 127, 137, 147, 157) are provided in the area of the expected medication (16), and the opening cuts (17, 37, 47, 57, 67, 77, 87, 97, 107, 117, 127, 137, 147, 157); are arranged exclusively along a segment of the contour of the medication (16) or along a segment of the contour of the medication

Abstract: A package for containing tablets or like items is provided and has child-resistant and senior-friendly dispensing properties. The package includes an outer sleeve having opposed first and second wall panels. The first wall panel has a series of separate tear-away tabs. A separate card is contained within the sleeve and has a plurality of separate compartments and at least one reinforcement rib. A series of separate push-through chads is provided by the packaging and are directly opposed from and aligned with the tabs. The reinforcement rib provides a column support between the first and second wall panels and is of a height greater than that of the compartments. Each compartment is located directly between and aligned with one of the chads and one of the tabs, and the reinforcement rib provides a pre-determined amount of spacing between the tabs and the compartments.

Abstract: Embodiments of a holder for a blister sheet used to manage prescription pills are described herein. The holder solves the problem of limited space in filled blisters of a blister sheet during visual verification of the contents thereof by including a frame to receive the sheet in such a way that at least some of the blisters are positioned in close proximity to verification receptacles also provided on the holder to temporarily receive part of the blisters' content.

Abstract: A multi-layered blister package includes a first panel having at least one blister pocket receiving aperture defined therein, wherein a blister pocket protrudes through the at least one blister pocket receiving aperture and retains an article therein. A second panel has at least one exit aperture defined therein, wherein the at least one exit aperture aligns with the at least one blister pocket receiving aperture when the first panel is disposed over the second panel. A third panel having at least one intermediate aperture defined therein, wherein the at least one intermediate aperture aligns with and is between the at least one exit aperture and the at least one blister pocket receiving aperture when the third panel is pivoted to a first position.

Abstract: Pharmaceutical compositions and dosage forms of dimethyl fumarate containing low levels of certain impurities are disclosed.

Abstract: A film container includes a bottom film and a top film connected thereto for forming at least one accommodating chamber for a filling, in particular a pharmaceutical active substance formulation. A detachably fastened sliding element which covers the accommodating chamber is assigned to the accommodating chamber as a safeguard.

Abstract: The present disclosure refers to a material impermeable to water vapour and oxygen for packaging dietary products, cosmetics and medicinal specialities. In particular, the present disclosure refers to primary packaging in the form of blister packs or sachets, which comes into direct contact with the formulations of medicinal specialities and dietary products and cosmetics, such as, for example, tablets, pills, pessaries, powders, granules, suppositories, rigid capsules and soft capsules (also known as soft gel capsules).

Abstract: The package supports a plurality of consumable products. The package is a blister package having a plurality of consumable products housed in a blister tray and covered with a rupturable sheet. The sheet overlies the open surfaces of the blister tray and includes rupturable locations formed thereon for permitting passage of the product therethrough.

Abstract: A system and method for communicating a multiple tablet order to a multiple tablet order production facility is described. The method includes communicating the multiple tablet order to the production facility, the verified multiple tablet order including a plurality of different tablets that are prescribed to be consumed at the same time. The multiple tablet package is filled with at least a first tablet and a second tablet that is different from the first tablet. The multiple tablet package is then sealed. An automated inspection of the sealed multiple tablet package after the multiple tablet package is filled with the first tablet and the second tablet is then performed. The automated inspection includes an inspection module that operates at visual wavelengths and analyzes a tablet color and a tablet shape.

Abstract: An online ordering system configured to process a multiple tablet order is described. The system comprises a database that stores information for a plurality of medicinal tablets and an online ordering server for receiving a plurality of multiple tablet orders. Each multiple tablet order corresponds to at least two tablets for consumption during a particular time on a particular date. The system further comprises a production facility server communicatively coupled to the database and the online ordering server. The production facility server is configured to control a production facility to fill the plurality of multiple tablet orders by placing the tablets associated with each order in a multiple tablet container. Each container is labeled with tablet specific information, including the date and the time for consuming the tablets in the container and a plurality of images of each of the tablets in the container.

Abstract: A package for storing an aerosolizable pharmaceutical formulation comprises a capsule adapted to contain the aerosolizable pharmaceutical formulation, and a moisture barrier around the capsule. The moisture barrier comprises a material that is resistant to moisture passage, whereby the moisture barrier reduces the amount of moisture in contact with the aerosolizable pharmaceutical formulation so that the aerosolizable pharmaceutical formulation may be aerosolized when the capsule is opened. In one version, the moisture barrier comprises a metal.

Abstract: This invention relates to a compliance blister package comprising a matrix of blisters arranged in a plurality of columns and plurality of rows which comprises a combination of one of the fixed dose combination dosage form comprising two or more therapeutically active ingredients loaded into blisters of one of the columns and the other dosage form which comprises one or more of therapeutically active ingredient form loaded into the successive column blisters for once a day administration or concurrent administration.