Abstract: The invention provides methods, compositions, and kits containing a minocycline topical suspension, for treating meibomian gland dysfunction and related disorders.

Abstract: A beverage supply apparatus 100 includes milk tank 3, milk flow path L3, pump 7 for delivering a beverage, air flow path L6, pump 9 for supplying air configured to be capable of changing the discharge flow rate, release path L7 for discharging air flowing through air flow path L6 to the outside, on-off valve V7, first throttle part 16, and second throttle part 17. One end of release path L7 is connected to release point Z8 in air flow path L6, and the other end is open to the outside. On-off valve V7 is disposed in a flow path extending between release point Z8 and pump 9 in air flow path L6, and opens and closes this flow path. Throttle part 16 is disposed in a flow path extending downstream of release point Z8 in air flow path L6, and throttle part 17 is disposed in release path L7.

Abstract: A cellphone case that dispenses perfume. The cellphone case defines a flat fluid reservoir that holds perfume. The flat fluid reservoir defines an atomizer nozzle that lines up with a nozzle aperture of the cellphone case, a push button activator that lines up with a trigger aperture of the cellphone case, and a refill inlet valve that lines up with a refill aperture of the cellphone case.

Abstract: The invention relates to an installation for producing a medical preparation, in particular for producing a preparation for parenteral nutrition. Liquids are transferred by means of the installation from a plurality of source containers to a target container. The installation comprises a receptacle with drivers for a valve block, wherein the drivers of the valves are arranged offset from one another.

Abstract: A portable sanitizer dispenser for use with a cellular phone includes a hand sanitizer dispenser configured to releasably engage at least one surface of a cellular phone. The sanitizer dispenser includes a compressible cavity defined therein configured to retain a sanitizer therein. The sanitizer dispenser further includes a nozzle disposed on an outer surface thereof. The nozzle is in fluid communication with the compressible cavity such that when pressure is applied to the compressible cavity, sanitizer is expelled from the nozzle.

Abstract: A gas pressure control valve having a valve body with a gas inlet and a gas outlet is described. An inner cap is provided bounding in part a chamber within the valve body in communication with the gas inlet. The valve body contains a spring loaded piston comprising a piston head and a piston rod. The piston rod includes a conduit providing communication between the chamber bounded in part by the inner cap and a chamber adjacent the piston head and the gas outlet. The piston is operable to move between a closed configuration in which the piston rod prevents communication between the gas inlet and the chamber bounded in part by the inner cap and an open configuration in which the piston rod permits communication between the gas inlet and the chamber bounded in part by the inner cap.

Abstract: A fluid dispensing assembly for providing a configurable fluid temperature. The assembly including: an adjustment interface; a mixing valve having a plurality of fluid ingress apertures and at least one fluid egress aperture; the mixing valve being adjustable to dispense fluid at a configurable temperature; and a dispenser element, in fluid communication with the at least on egress aperture of the mixing valve and adapted to selectively dispense water there from.

Abstract: A system and method for mixing and dispensing two substances are provided. The system includes: a first substance a first container for containing a first substance, a second container for containing a second substance, a feeding tube, and a pumping system connected to the first container, the second container, and the feeding tube; wherein the system comprises at least three modes of operation: combining the first and second substances into one combined substance, mixing the combined substance, and dispensing the mixed substance; and wherein the pumping system is adapted to perform the at least three modes of operation and dispense the mixed substance to the feeding tube.

Abstract: A drinking cup that has a lid with a receiving portion is provided. The receiving portion may have a flow control engagement surface. A flow control element that may be configured for releasable attachment with the lid may be included and can have an attachment portion. The attachment portion may have a lid engagement surface. When the flow control element and the lid are attached, the flow control engagement surface engages the lid engagement surface. At least one of the flow control engagement surface and the lid engagement surface may have a concave shape.

Abstract: A fillable closure is used to initiate emptying of a separately fillable capsule molded into this closure. The capsule is made oxygen-impermeable on the inside or outside with a vapor-deposited layer of silicon dioxide or metal. The volume of the capsule can be reduced through pressurization from the top, through deformation of its side walls, for cutting or rupturing a sealing foil. The capsule has an asymmetric push button with a pusher surface, a deformable front and side wall and a stable rear wall. The upper end of the rear wall forms a stationary edge, on which the pusher surface can be pivoted downward through deformation of the front and side wall. On the bottom of the pusher surface, a triangle-shaped blade is formed, which ends in a tip, and its triangle edge forming a cutting edge for piercing and cutting the sealing foil on the bottom of the capsule.

Abstract: A water dispenser is provided which allows air in a warm water tank to be discharged through a tank connecting line when introducing drinking water into the empty warm water tank. The water dispenser includes a check valve (20) provided in the tank connecting line (7), through which a cold water tank (2) is connected to the warm water tank (3). The check valve (20) includes a valve body (22) having a specific gravity smaller than that of drinking water, and is configured such that while there is no drinking water in the valve sleeve (21), the valve body (22) is moved downward by gravity such that the valve hole (25) opens, and such that while the interior of the valve sleeve (21) is filled with drinking water, the valve body (22) moves upward due to buoyancy until the valve hole (25) is closed by the valve body (22).

Abstract: A dispenser platform for receiving a product container, having a casing, wholly or partially encasing a control panel coupled a control module and a product container receptacle having a product container coupling assembly. The product container coupling assembly includes a first product supply conduit configured to receive a barrel of a product container. A second product supply conduit couples to a reservoir or to a supply of a second product, such as water. The product container holds a first product, such as concentrated coffee, concentrated tea, concentrated flavored drink, flavored syrup (cola) or concentrated juice. Components of the dispenser platform include a pump assembly, a heating and/or cooling assembly responsively coupled to a control panel via a control module and a filter assembly. The product container can be a BOV container or an airless dispensing container.

Abstract: A wall mounted dispenser for dispensing a mixture of water and liquid chemicals which may be used as a separate dispenser or in combination with other like dispensers. The dispenser of this invention includes several backflow preventers to ensure that the water supply will not become contaminated during backflow problems.

Abstract: A container assembly has a first container that operably houses a second container. The first container is configured to hold a first flowable substance, and the second container is configured to hold a second flowable substance. The second container is rupturable, preferably by manipulation through the first container, wherein the second flowable substance can mix with the first flowable substance to form a mixture. The first container is also rupturable to dispense the mixture therefrom.

Abstract: A storage and dispensing container includes: a housing having a bottom plate with a feed opening defined therein, and a generally cylindrical outer wall extending around an outer periphery of the bottom plate; a funnel disposed at a lower end of the housing, in flow communication with the feed opening; a drum having an outer wall defining an interior that is partitioned into at least two chambers which are open at upper and lower ends thereof, the wall including a cylindrical portion which is coupled to the outer wall of the housing, such that the drum is rotatable relative to the housing; and a removable cap which closes off the upper end of the drum.

Abstract: A dual dispensing apparatus for dispensing two flowable components having a first storage chamber for the first component, and a second storage chamber for the second component. The two storage chambers are arranged next to one another and each have an outlet for the first or the second component respectively at their distal ends. The apparatus also has a first plunger for penetrating into the first storage chamber and a second plunger for penetrating into the second storage chamber. A respective piston for dispensing the respective component is molded to each plunger and is sealingly guided by the respective wall of the storage chamber. Each storage chamber has at least one first guide element at its end remote from the outlet and each plunger has at least one second guide element adjacent to the respective piston. The first and the second guide elements are configured for mutual engagement.

Abstract: An applicator assembly for mixing at least a first and second component is provided. The applicator assembly includes a manifold configured for operable engagement with at least a first and second source of component, the manifold including at least a first and second component channel therethrough, an elongated shaft extending distally from the manifold, the elongated shaft including at least a first and second component lumen extending the length thereof, the at least first and second component channels in fluid communication with the at least first and second component channels, a tip assembly defining a first chamber, an intermediate chamber and a final chamber.

Abstract: A mixing module that includes a mixing chamber formed of a cold flow material and placed within a housing which includes a compression device for compressing the cold flow material through which extends a reciprocating rod, preferably in the form of a valve rod relative to one or more chemical ports formed in the mixing chamber to mix or deliver chemicals within a mixing reception recess. The mixing chamber features a locking arrangement between the cold flow material mixing chamber and the housing which acts to prevent movement of the mixing chamber within the housing due to a sticking of the reciprocating rod to the mixing chamber which otherwise produces a position change in the mixing chamber as the compression device is temporarily compressed until the rod be comes unstuck and releases.

Abstract: A beverage dispensing system comprising a dispensing device including a dispensing valve for dispensing a beverage, an actuator for initiating the dispensing of said beverage through said valve, a display screen having a user interface being coupled to said dispensing device, wireless communication electronics coupled to said beverage dispensing system and adapted to communicate with a wireless transponder and a controller functionally connected to said at least one dispensing valve, said display screen and said wireless communication electronics.

Abstract: A dispenser apparatus (2) for a curable liquid material is disclosed. The apparatus comprises a flexible bag (8) defining a first compartment (10) for accommodating a first component of a curable liquid material, and a second compartment (12) for accommodating a second component of the curable liquid material and adapted to communicate with the first chamber to enable mixing of the first and second components to initiate curing of the curable liquid material. A first clamp (14) temporarily prevents mixing of the first and second components, and an elongate nozzle (16) communicates with the second compartment to dispense the mixed curable liquid material therefrom. A second clamp (18) temporarily prevents passage of the curable liquid material from the second compartment to the nozzle.

Abstract: A dispensing device is disclosed having an ampoule with at least four storage lumens extending axially along the length of an ampoule body, a mixing tip coupled to a distal end of the storage lumens, the mixing tip having at least four gasket seats formed therein, each gasket seat corresponding to one of the storage lumens, and an outlet lumen in fluid communication with the storage lumens.

Abstract: A powdered and liquid chemical distribution system for distributing powdered and liquid chemicals. The system includes a transport module having a plurality of chambers arranged in series to automatically distribute both a powdered chemical and a liquid chemical to a point of use along a single line, wherein the plurality of chambers share a chamber wall.

Abstract: An internal chamber incorporated with the cap of a container, for example, a disposable beverage bottle. The internal chamber has an internal bore designed to hold a powder or liquid that can be released into the container. The chamber is inserted into a bottle or similar container when the cap is placed over the opening. A push-button on the top of the cap advances an actuator within the internal bore to push a diaphragm out of the distal end outlet port in the chamber to release the ingredient(s) within the internal chamber into the container. The diaphragm also has two or more peripheral guide rails to ensure that it remains aligned with the chamber housing during those movements. Alternative embodiments utilize a dome cover over the push-button. In use, the cap of the container can be removed, which will simultaneously remove the chamber, allowing the liquid in the container to be consumed or decanted.

Abstract: An integrated beverage blending system comprising an ice portion control module, an ingredient module; an ice dispensing conduit in communication with the ice portion control module, and an ingredient dispensing valve removably connected to the ice dispensing conduit and in communication with the ingredient module. Ice is dispensed into a beverage container via the ice dispensing conduit and the ingredient is dispensed into the beverage container via the ingredient dispensing valve.

Abstract: The present disclosure is drawn to a disinfectant system which can be used to disinfect surfaces. The system includes a first chamber containing a first solution and a second chamber containing a second solution. The first solution can include an alcohol, an organic carboxylic acid, and from 0.01 ppm, to 1,000 ppm by weight of a transition metal or alloy thereof based on the first solution weight content. The second solution can include hydrogen peroxide. The system further includes a dispenser through which the system is configured to mix and dispense the first solution and the second solution immediately before being dispensed. A peracid composition is formed upon mixing of the first and second solutions.

Abstract: A reconstitution device (10) for mixing a first component (70) with a second component (72) wherein there are provided first and seconds housings (12, 14) which are engageable together, a conduit (28) having an internal passageway (30) having a dispensing end and an inlet end, first, second and third plungers (52, 54) mounted in said internal passageway (30), first and second compartments (70, 72) being defined by the plungers, a shearing channel (32) formed in a side wall of conduit (28) to permit mixing of contents located in the first and second compartments (74, 76), a plunger rod (58) to cause initial mixing of the first and second components (70, 72), and a spring member (48) biasing against the moveable member (42).

Abstract: A childproof closure for a dispensing apparatus (5) having first bayonet fastening means (20), wherein the closure (40, 50, 80, 100) has second bayonet fastening means (21). One of the two bayonet fastening means (20, 21) has bayonet lugs (30, 32) which can be introduced into corresponding socket elements (25, 27) of the other bayonet fastening means (20, 21). Both bayonet fastening means (20, 21) moreover have coding elements (13, 23, 35, 38) for a preset alignment of the closure (40, 50, 80, 100) and of the dispensing apparatus (5). The closure (40, 50, 80, 100) has a closure element (40, 50) having first engagement elements (43, 70) and a securing cap (80, 100) which at least partly covers the closure element (40, 50) and has second engagement elements (75, 130). The securing cap (80, 100) and the closure element (40, 50) are connected cohesively strongly, but rotatably with respect to one another, by means of shape-matched elements (58, 60, 90, 120).

Abstract: A dispensing nozzle assembly for dispensing a number of micro-ingredients into a fluid stream. The dispensing nozzle assembly may include a micro-ingredient mixing chamber, a number of micro-ingredient lines in communication with the micro-ingredient mixing chamber such that the micro-ingredients mix therein, and a mixed micro-ingredient exit such the mixed micro-ingredients are dispensed into the fluid stream.

Abstract: A beverage dispensing apparatus may be adapted to mix together a concentrate fluid with a base fluid. In particular implementations, an apparatus may include a trunk line carrying the base fluid, a manifold, an inline and an outline extending between the trunk and the manifold, a python and a bar gun assembly fluidly connected to the downstream side of the manifold by a plurality of conduits contained in the python, wherein the apparatus includes a recirculation channel having an inlet port and an outlet port fluidly connected to respective in and out conduits in the python, the said in and out conduits being fluidly connected respectively to the inline and the outline of the cool fluid trunk line via the manifold, the beverage dispensing apparatus further including a plurality of product lines, a mixing mechanism and a dispensing outlet.

Abstract: A nozzle system for use with a multi-flavor beverage dispenser includes a mixing chamber having a fluid outlet therefrom; a diluent injector configured to deliver a mixing fluid from without to within the mixing chamber; and a number of concentrate injectors configured to independently deliver a fluid concentrate from without to within the mixing chamber. The concentrate injector each have associated therewith a self-sealing dispensing valve configured to substantially limit fluid flow through its respective concentrate injector to from without the mixing chamber to within the mixing chamber.

Abstract: A frangible blister packaging for mixing and dispensing fluid at point of use. A multi-compartment force activated container formed by sealing a lidding closure material over formed fluid filled independent containment cavities interconnected by a pressure release frangible sealing area there between. A mixing flow path is initiated by compression on the upstream flexible compartment, forcing content fluid to mix into the downstream compartment for dispensing therefrom. The frangible sealing area is formed independently of the container compartment sealing assuring a force fluid transfer stream projection for maximum fluid inter-mixing before dispensing by compression of upstream compartment.

Abstract: The present application describes a product dispenser. The product dispenser may include at least one macro-ingredient source, at least one micro-ingredient source positioned about the dispenser, a diluent source, a dispensing valve, a number of pumps or metering devices, and a user interface. The user interface receives a request for a product type and instructs the pumps or metering devices to dispense a predetermined type and ratio of macro-ingredients, micro-ingredients, and diluent to the dispensing valve for a predetermined flow rate.

Abstract: A multi-chamber dispenser may be provided and may include one or more chambers that may be removably fastened to a rigid frame and/or one or more chambers that may be permanently fastened to the rigid frame. A chamber may be actuated by rotating a cap, or an actuator, or both, to an application position and then pressing the cap or actuator in order to dispense the substance of one or more chambers. The substance may be dispensed via an independent dispensing conduit or a shared dispensing conduit. The multi-chamber dispenser may operate in any orientation and may operate when less than all of the chambers are fastened to the dispenser.

Abstract: Devices, systems, and methods are provided for controlling a quantity of cutting fluid dispensed for a cutting tool within a CNC or other machining system. The devices, systems, and methods may include controlling multiple fluids such that coolant, lubricant, or other fluids can be delivered at different locations, at different flow rates, have their flow rates changed independently, and/or have their flow rates changed dynamically during a machining operation. In some embodiments, a feedback loop or input may be provided to obtain and/or provide information regarding the machining operation—such as cutting force, cutting temperature, cutting friction, machining operation, tool in use, work piece geometry, and/or material—and automatically and/or independently modify the fluid flow rates. The fluid may be atomized with air or other gases to minimize the quantities of fluid used. Components in the system may be modular to allow the system to be used with existing and new machining technologies.

Abstract: The subject matter of the present application is a cold-curing two-component-epoxy adhesive, comprising (a) an epoxy-resin-component and (b) a curing agent-component, comprising a mercaptan curing agent, in which the epoxy-resin-component comprises a color change indicator. Also described is a method for monitoring the curing progress of cold-curing two-component-epoxy adhesive via color change of the adhesive.

Abstract: Methods, apparatuses, and systems for dispensing an off-gassing liquid product mixed with a diluting product are provided. A liquid product or product solution is moved through a primed product line and towards a dispenser. The liquid product is combined with the diluting product to create a solution. The solution is dispensed. The product line is cleared of unused or displaced liquid product by redirecting at least a portion of the unused or displaced liquid product in the product line to a displacement system operatively attached to the product line. The displacement system includes a check valve including a crack pressure that allows the unused or displaced product to be dispensed back into the product source or a separate, secondary container.

Abstract: Methods, apparatuses, and systems for dispensing an off-gassing liquid product mixed with a diluting product are provided. A liquid product or product solution is moved through an unprimed product line and towards a dispenser. The liquid product is combined with the diluting product to create a solution. The solution is dispensed. The product line is cleared of unused liquid product to unprime the product line after the dispensement of the solution. The unused product may be directed back into a product container from which it was held.

Abstract: This invention relates to a flexible membrane separation valve, comprising a housing (120), the lateral surfaces of which are provided with slits (121), within which housing (120) a flexible membrane (122) with cylindrical symmetry is housed, within which an insert (130) having a body (131) with cylindrical symmetry is in turn housed, the insert (130) comprising a proximal end (132) having a proximal apex (133) spaced along the longitudinal axis of the insert (130) from a base (134) with cylindrical symmetry, through which the proximal end (132) joins to the body (131), the proximal apex (133) being joined to the base (134) through a continuous surface, the valve being characterised in that the proximal end (132) has an axial section such that tangent lines to the proximal apex (133) form an angle containing the longitudinal axis of the insert that is lower than or equal to 90°. The invention further relates to an apparatus for mixing a liquid comprising such a flexible membrane separation valve.

Abstract: A device (1) for manufacturing a three-dimensional object by a layer wise solidification of a building material at positions in the respective layers that correspond to the object is provided. A feed (96) that supplies the building material to a building space (10) in the device (1) and at least two filler portions (98a, 98b) that are provided at the feed (96) and are independent from one another are provided, wherein one connector (99a, 99b) is provided for each building material supply container (100a, 100b) in order to supply the building material from outside of the device (1).

Abstract: A dispenser (10) for dispensing flowable materials has a container assembly (12) having a dividing wall (19). A first chamber (18) and a second chamber (20) are defined in the container assembly (12). The first chamber (18) is configured to contain a first flowable material (M1) (140) and the second chamber (20) is configured to contain a second flowable material (M2) (142). A membrane (34) is positioned in the container and cooperates with the dividing wall (19) to enclose the first and second chambers (18, 20). The membrane (34) has a first section (132) having a first weld seam (148) and a second section (134) having a second weld seam (150). The first section (132) is separated from the second section (134) by a non-rupturable member (33). Rupture of the membrane (34) allows the flowable materials into a third chamber (42) in which the flowable materials mix to form a mixture, and from which the mixture is dispensed.

Abstract: A portable refrigeration system having a refrigerator unit with a door surface, aperture surface, dispenser surface, and inner cavity, a door pivotally attached to the door surface which can move between an open and closed position allowing and preventing access to the inner cavity, the unit further having standard refrigeration components for cooling the inner cavity, a base, the unit is mounted atop the base such that a gap exists between the dispenser surface and base, a first, second, third and fourth aperture are in the aperture surface, a lid removably attached to the aperture surface functioning to temporarily cover the apertures, which can move between an open and closed position allowing and preventing access to the aperture, a dispenser on the dispenser surface having a first dispenser for water or liquid and a second dispenser for ice, and a plurality of control buttons on the unit.

Abstract: A quick and convenient method for coloring hair is disclosed. According to an embodiment, a hair dye applicator is provided. The hair dye applicator includes two containers that can be locked together prior to use. Each container can include at least one hair dye component. In one embodiment, a first container can include a hair color component while the second container can include a developer.

Abstract: Colorant fluid dispensing device (1) for dispensing multiple colorant fluids, comprising more than one fluid container (2) at least one dispenser outlet (3), wherein the fluid containers are in fluid connection with the at least one dispenser outlet via pumping means (4) the pumping means comprises more than one piston pump (5), each piston pump comprises a central pump tube (15) in which a piston (20) is provided with a piston rod (21) for moving the piston inside the central pump tube, the colorant fluid dispensing device further comprises driving means (36) for moving the piston rods of said piston pumps, control means (38) for controlling the driving means, and the driving means comprises a movable selector (37) configured to engage the piston rods of a selection.

Abstract: A method of measuring or dosing dry mixture ingredients includes providing separate flow channels for ingredients. The flow channels including at least a first flow channel and a second flow channel configured such that the first flow channel is at least partially disposed around the second flow channel. The first flow channel may include an outer concentric metering screw and the second flow channel may include an inner concentric metering screw. The method further including providing a first material to the first flow channel and a second material to a second flow channel, wherein one of the first and second materials comprises a single dry ingredient and the other of the first and second material comprises multiple dry ingredients. The materials are advanced through the channels to a shared exit where a mixing zone is provided.

Abstract: A fluid container unit including: a container coupling for coupling a supply/discharge port of a first container with a supply/discharge port of a second container; a single nozzle member having a nozzle tube; a connection cap having a first end for holding a base portion of the nozzle member and a second end for covering one side of the container coupling by fitting around an outer periphery thereof; an intermediate adaptor having a pair of pusher elements facing the first and the second supply/discharge ports, respectively; and a supply/discharge port opening mechanism for moving the intermediate adaptor toward the container coupling and opening the supply/discharge ports by the pusher elements. The pusher elements are movably held in a direction along a longitudinal axis of the nozzle tube in the connection cap.

Abstract: The invention relates to the field of food industry, more particularly, to commercial equipment, and is useful in apparatuses for dispensing beer and other foaming and/or carbonated beverages from an isobaric storage to plastic bottles or glasses for sale in retail kiosks, shops, restaurants, and bars. The technical result of the present invention is a simplified maintenance both of the apparatus for a manual dispensing of beverages as a whole due to excluding the need for a sanitary treatment of a part of the filling pipe each time a container is filled and a simplified maintenance of taps due to eliminating the need for frequent washing of units and parts of these means after the dispensing of beer or another beverage is over. The technical result is reached by two embodiments of the three-way cock (6364), which are installed in the apparatus for a manual dispensing of foaming and/or carbonated beverages to uncovered containers (54).

Abstract: The present invention relates to a multi-chamber container having a container housing (4), which comprises a first chamber (1) for receiving a first product component and a second chamber (2) for receiving a second product component. The container further has a device (15, 16; 60, 61) for producing a pressure difference delivering the first and/or second product components out of the respective chamber, a removal opening (33), which communicates with the first chamber (1) and/or the second chamber (2) and is disposed on a housing head (3, 53), and further a metering device (3, 15, 16; 60, 61, 66) for dispensing the product component from the first and/or second chambers (1, 2). The object of the present invention is to provide a multi-chamber container, which has a relatively space-saving and compact design.

Abstract: A fluid application system includes a diluent reservoir, a chemical container, a sprayer housing, a manifold located in the sprayer housing, and a pump assembly in fluid communication with an outlet of the manifold. The manifold includes a diluent inlet in fluid communication with the diluent reservoir, a chemical inlet in fluid communication with the container, a mixing chamber in fluid communication with the diluent inlet and the chemical inlet and the outlet of the manifold. The pump assembly draws a mixture of the chemical and the diluent from the manifold and sprays the mixture of the chemical and the diluent from the nozzle.

Abstract: A metering component for a two-component dispensing gun includes a first metering rod and a second metering rod. The first metering rod includes a first tip section at one end that terminates into a first intermediate sealing section. The first intermediate sealing section terminates at a first base section at an opposite end of the first tip section. The second metering rod includes a second tip section at one end terminating in a second intermediate sealing section, wherein the second intermediate sealing section terminates at a second base section at an opposite end of the second tip section. The first metering rod is interconnected to the second metering rod at the first base section and the second base section.

Abstract: The invention pertains to a cartridge (1) with at least one chamber (6a, 6b) for accommodating a substance that respectively features a dispensing opening (11a, 11b) and another opening that is closed by a piston (8a, 8b) that can be displaced in the chamber and serves for dispensing the substance. The cartridge (1) furthermore features a piston rod mechanism (4) for displacing the piston (8a, 8b) in the chamber (6a, 6b). In this case, the piston rod mechanism is composed of several piston rods (14, 14a, 14b, 15, 15?) that can be transferred from a first dispensing stage to a second dispensing stage with the aid of a spring element (18, 18a, 18b).