Abstract: Colloidal formulation for staining proteins and methods of their use are provided.

Abstract: Provided are synthetic dendrimer calibrants for mass spectrometry. The calibrants are distinguished by their relative ease and rapidity of synthesis, comparatively low cost, long shelf life, high purity, and amenability to batch synthesis as mixtures. The latter characteristic enables parallel preparation of higher molecular weight compounds displaying useful distributions of discrete molecular weights, thereby providing multi-point mass spectrometry calibration standards. Methods of making, tuning and using said calibrants are provided.

Abstract: The present invention is a method of tagging resin product such that it can be identified. The method involves adding a series of tracer elements to a resin in specific amounts. The relative amounts of one or more of such tracer elements for each desired unit of production are varied, such that each unit of production has a unique combination of ratios of the various tracer elements.

Abstract: A simulant that includes a carrier and DNA encapsulated in the carrier. Also a method of making a simulant including the steps of providing a carrier and encapsulating DNA in the carrier to produce the simulant.

Abstract: The present invention concerns new monolithic shaped bodies, a method for their preparation as well as their use especially for the selective purification and separation of biopolymers. A chromatographic separation material is provided with the new monolithic shaped bodies that allows a selective, efficient and reproducible purification and separation of biopolymers.

Abstract: An electrical temperature sensor (10) comprises a liquid crystalline material (12). First and second electrically conductive contacts (14), (16), having a spaced relationship therebetween, contact the liquid crystalline material (12). An electric property measuring device is electrically connected to the first and second contacts (14), (16) and is arranged to measure an electric property of the liquid crystalline material (12). The liquid crystalline material (12) has a transition temperature T at which it undergoes a phase change between polar and non-polar phases. The phase change between polar and non-polar phases causes a change in said electric property of the liquid crystalline material (12).

Abstract: A residue remaining on an object to be cleaned after cleaning is easily detected and observed on the object. Adhesive materials 2A and 2B for use in residue confirmation, which are applied in advance to an object 1 to be cleaned for confirmation of a residue remaining on the object 1 after cleaning, are formed by coloring chips produced during cutting work. The adhesive materials 2A and 2B are preferably formed by coating and coloring the chips with paint, the paint emitting visible light in an excited state.

Abstract: Disclosed herein is a method for identifying the compounds contributing to a pungent odor from an air conditioner, a method for artificially reproducing the pungent odor, and preparing a corresponding pungent odor composition. Through the analysis method of the present invention, the compounds contributing to the pungent odor from an air conditioner may be identified and quantified. The pungent odor may be reproduced from a combination of the compounds identified by the analysis method of the present invention. The reproduced pungent odor may provide significant data required for development of an apparatus and a method for removing specific odors.

Abstract: The invention concerns an article of manufacture that is a manufactured product marked with a microparticle and a method of marking manufactured produces. The microparticle tag includes a predetermined code embedded in its physical structure by refractive index changes between different regions of the particle. The particle has a diameter of a few hundred microns or less and has a plurality of layers.

Abstract: A method that identifies the compounds contributing to a fish-like odor from an air conditioner and artificially reproduces the fish-like odor, and prepares a corresponding fish-like odor composition. Through the analysis method of the present invention, the compounds contributing to the fish-like odor from an air conditioner are identified and quantified. The fish-like odor is reproduced from a combination of the compounds identified by the analysis method of the present invention. The reproduced fish-like odor provides significant data required for development of an apparatus and a method for removing specific odor.

Abstract: A method that identifies the compounds contributing to a sweet odor from an air conditioner, reproduces the sweet odor, and prepares a corresponding sweet odor composition. Through the analysis method of the present invention, the compounds contributing to the sweet odor from an air conditioner are identified and quantified. The sweet odor is reproduced from a combination of the compounds identified by the analysis method of the present invention. The reproduced sweet odor provides significant data required for development of an apparatus and a method for removing specific odor.

Abstract: A substrate mimicking intercellular lipids in stratum corneum consisting of a substrate and a lipid membrane formed on the substrate, wherein the lipid membrane is formed from ceramide, palmitic acid and cholesterol, and the ceramide, palmitic acid and cholesterol are present at a mass ratio of 20-70%:10-60%:20-40% (ceramide:palmitic acid:cholesterol).

Abstract: A method is provided that identifies the compounds contributing to a malodor from an air conditioner, reproduces the malodor, and prepares a corresponding malodor composition. Through the analysis method of the present invention, the compounds contributing to the malodor from an air conditioner are identified and quantified. The malodor is reproduced from a combination of the compounds identified by the analysis method of the present invention. The reproduced malodor provides significant data required for development of an apparatus and a method for removing specific odor.

Abstract: Various embodiments of the present disclosure pertain to nanocomposites for detecting hydrocarbons in a geological structure. In some embodiments, the nanocomposites include: a core particle; a polymer associated with the core particle; a sulfur-based moiety associated with the polymer; and a releasable probe molecule associated with the core particle, where the releasable probe molecule is releasable from the core particle upon exposure to hydrocarbons. Additional embodiments of the present disclosure pertain to methods of detecting hydrocarbons in a geological structure by utilizing the nanocomposites of the present disclosure.

Abstract: A security substrate may include at least one area for authentication and/or for revealing attempts at forgery using solvents. The at least one area may include individualized polymer- or copolymer-based particles comprising at least one visible or detectable marker. The polymer or copolymer may be at least partially soluble in solvents used for forgery.

Abstract: Porous masses that include taggants may provide for product authentication and counterfeit identification, especially products like smoking device filters and smoking devices. In some instances, a tagged porous mass may include a plurality of binder particles; a taggant that comprises at least one taggant component selected from the group consisting of an elemental marker, a molecular fluorophore, a particulate fluorophore, and any combination thereof; a plurality of second particles, wherein the second particles comprise at least one selected from the group consisting of active particles, organic particles, and any combination thereof; and wherein the binder particles are bound to the second particles at sintered contact points.

Abstract: Cellulose ester films may include taggants to provide for product authentication and counterfeit identification, especially in packaging applications. In some instances, a tagged cellulose ester film may include cellulose ester, a plasticizer, and a taggant, wherein the taggant comprises at least one taggant component selected from the group consisting of an elemental marker, a molecular fluorophore, a particulate fluorophore, and any combination thereof.

Abstract: In certain embodiments, a method for validating the human visual inspection process or an optical analysis instrument for use with biological particles may include inspecting a standard particle solution using the optical analysis instrument. The standard particle solution may include a known concentration of standard particles suspended in solution with the standard particles having a defined size and shape distribution. The standard particles may have a refractive index that is substantially similar to a refractive index of the biological particles. The method may include assessing a concentration of standard particles in the standard particle solution from the inspection. The method may include assessing a difference between the assessed concentration of standard particles and the known concentration of standard particles. The method may include modifying one or more parameters of the optical analysis instrument based on the assessed difference between the concentrations.

Abstract: The present invention relates to the use of non-deactivatable security compositions comprising the combination of at least two types of particles of oxide materials, where said particles have a different size and/or morphology, and where the inorganic oxide materials have at least one transition metal or one lanthanide element, and radiofrequency wave absorption properties. The invention also relates to security articles, documents or elements incorporating these compositions, as well as to a method and to a system for detection thereof.

Abstract: Industrial fluids may be monitored at the site of each industrial fluid by introducing a sample of the industrial fluid into a device employing a detection technique for detecting at least one composition within the sample. The detection technique may be or include surface enhanced Raman scattering (SERS), mass spectrometry (MS), nuclear magnetic resonance (NMR), ultraviolet light (UV) spectroscopy, UV spectrophotometry, indirect UV spectroscopy, contactless conductivity, laser induced fluorescence, and combinations thereof. In one non-limiting embodiment, a separation technique may be applied to the sample prior to the introduction of the sample into the device for detecting the composition.

Abstract: A phantom for medical imaging instrumentation, the phantom including a first hydrogel matrix, said matrix containing additives for simulating the optical and acoustic properties of a living organ or tissue. In the phantom, the additives include Indian ink or haemoglobin, silica powder and titanium dioxide powder. The phantom may contain a tumor simulator in solid or liquid form. It may also comprise several hydrogel matrices, each matrix including additives in different concentrations depending on the organ or tissue simulated. A method of producing the phantom includes one or more freeze-thaw cycles for optimizing the characteristics of the phantom.

Abstract: An immersion liquid for microscopy is provided, comprising (a) an organic compound which contains a saturated polycyclic hydrocarbon residue, (b) an oligomeric or polymeric saturated acyclic hydrocarbon and (c) an alkyl aromatic compound, selected from the group consisting of alkyl naphthalene and alkyl biphenyl.

Abstract: A method for manufacturing a test paper is disclosed in the present invention, and at least comprises the following steps. First, a chemical precursor comprising at least a reducing agent is coated onto a substrate. The substrate is then dipped into a metal salt solution comprising a plurality of metal ions for a predetermined time to reduce the metal ions to form metal particles on the substrate. Finally, the substrate is taken out and dried to complete a manufacture of at least a test paper. In the meantime a method for using the test paper, and a chemical composition used in the abovementioned for manufacturing the test paper are also disclosed in the present invention.

Abstract: A method for fabricating composite porosity standards may include the steps of providing a plurality of uncured composite coupons, each uncured composite coupon being formed from a composite material, providing a plurality of curing processes, selecting a curing process for each of the uncured composite coupons, curing each uncured composite coupon in accordance with a selected curing process to form a plurality of cured composite coupons, each cured composite coupon being formed from the composite material and having a percent porosity, measuring the percent porosity of each cured composite coupon, and correlating each measured percent porosity of a plurality of measure percent porosities to a corresponding cured composite coupon of the plurality of cured composite coupons to form a plurality of porosity standards.

Abstract: A method comprising injection molding a plastic part from a polymer formulation comprising an injection moldable thermoplastic and an additive, wherein the additive has a decomposition temperature that establishes a maximum processing temperature for the polymer formulation. The additive will thermally decompose to generate gaseous products causing visible bubble formation in the surface of the plastic part in response to exposure to a processing temperature that exceeds the decomposition temperature of the additive. A suitable additive may be, for example, selected from oxalates, carbamic acids, carbonic acids, diazocarbonyl compounds, and combinations thereof.

Abstract: The disclosure provides a method for quantification of hepatic function in a subject comprising measuring the clearance of an orally administered isotopically labeled cholic acid in a subject with, or suspected of having or developing, a hepatic disorder, for example, chronic hepatitis C. The disclosure further provides methods and kits for assessment of hepatic function.

Abstract: A synthetic urine solution and method of its manufacture are disclosed. The solution includes water having a pH between about 3 and about 10. The solution further includes creatinine, a means for removing bacteria from the solution so as to control or eliminate sepsis of the urine solution, preferably through the use of a biocide, and a urea-based compound. The solution exhibits a specific gravity of from 1.005 g/cm3 to 1.025 g/cm3. Additional compounds may also be included to further enhance the aesthetics or apparent authenticity of the synthetic urine.

Abstract: An absorbent article includes a topsheet layer, a backsheet layer and one absorbent core layer. The topsheet layer, absorbent core layer and backsheet layer each include a longitudinally directed side peripheral edge. The absorbent article further includes an aqueous medium-sensitive coating composition for triggered release of active ingredients from the absorbent article. The aqueous medium-sensitive coating composition is affixed to the absorbent article adjacent a longitudinally directed side peripheral edge. The coating composition includes a betaine ester or betaine ester derivative having a functional active group derived from a fragrance with a hydroxyl group, a color changing visual indicator chemistry, where the visual indicator chemistry is selected from at least one of the group of a pH indicator dye and pH adjuster, a thermochromic dye and a polarity-sensitive dye.

Abstract: This invention relates to a method that can be used to scientifically fabricate pseudoscents of narcotics, which, in their entirety, are comprised of non-narcotic materials. It also discloses specific compositions of such pseudoscents, which can be used as narcotic-free-but-odoriferously-identical simulants for a range of narcotics and are comprised of non-narcotic components of the scent signature of a narcotic and/or scent components of the same headspace scent signature that have narcotic qualities but have been rendered non-narcotic. The scents achievable by the groups of formulations generated by this method include the different types of prohibited and controlled narcotics, and the components within the pseudoscents can be further tuned to generate simulants representative of different qualities and quantities of such narcotics.

Abstract: Disclosed herein is a protein standard for gel electrophoresis. The standard may be detected using multiple modalities. These modalities include, for example, observation of color or fluorescence arising from dyes, porphyrins, or haloalkylated tryptophan residues covalently linked to proteins of the standard; or detection of fluorescence or chemiluminescence arising from antibodies or other binding partners bound to proteins of the standard through polypeptide epitopes or affinity tags. The protein standard comprises multiple protein sets, each set corresponding to a different gel band, and proteins within a set may be detectable with one or more modalities.

Abstract: Disclosed herein is a method for identifying compounds contributing to a sour odor emitting from an air conditioner, a method for artificially reproducing the detected sour odor and preparing a corresponding sour odor composition. Through the analysis method of the present invention, the compounds contributing to the sour odor emitted from an air conditioner may be identified and quantified. The detected sour odor may be reproduced from a combination of the compounds identified by the analysis method of the present invention. The reproduced sour odor may provide meaningful data required for development of an apparatus and a method for removing specific odors.

Abstract: Disclosed herein is a method for identifying the compounds contributing to urine odor emitting from an air conditioner, a method for artificially reproducing the detected urine odor, and preparing a corresponding urine odor composition. Through the analysis method of the present invention, the compounds contributing to the urine odor emitted from an air conditioner may be identified and quantified. The detected urine odor may be reproduced from a combination of the compounds identified by the analysis method of the present invention. The reproduced urine odor may provide meaningful data required for development of an apparatus and a method for removing specific odor.

Abstract: A rubber article comprising: a rubber substrate; and an indicator carried by said rubber substrate, said indicator including at least one component including porous ceramic particles that are at least partially saturated with a liquid, where the particles are transparent when at least saturated with the liquid.

Abstract: Industrial fluids may be monitored at the site of each industrial fluid by introducing a sample of the industrial fluid into a device employing a detection technique for detecting at least one composition within the sample. The detection technique may be or include surface enhanced Raman scattering (SERS), mass spectrometry (MS), nuclear magnetic resonance (NMR), ultraviolet light (UV) spectroscopy, UV spectrophotometry, indirect UV spectroscopy, contactless conductivity, laser induced fluorescence, and combinations thereof. In one non-limiting embodiment, a separation technique may be applied to the sample prior to the introduction of the sample into the device for detecting the composition.

Abstract: The present description discloses a novel biologically active ingredient of manuka honey. Specially, the present description discloses a compound represented by the following formula. In this formula, each of R1, R2 and R3 independently represents a hydrogen atom or optionally substituted C1-4 alkyl group, m represents an integer from 1 to 3, each of R4-m, R5-m and R6-m independently represents a hydrogen atom or optionally substituted C1-4 alkyl group, and each of R7, R8, R9 and R10 independently represents a hydrogen atom or optionally substituted C1-4 alkyl group.

Abstract: Provided herein are compositions and methods useful for preparing and analyzing a sample on a substrate by matrix assisted laser desorption ionization (MALDI) mass spectrometry (MS). In some embodiments, compositions provided herein comprise a substrate, matrix and nanoparticles, and sometimes comprise one or more additives and sometimes an analyte. Compositions provided herein sometimes comprise nanoparticles that include or are made up of silicon dioxide.

Abstract: A method comprising injection molding a plastic part from a polymer formulation comprising an injection moldable thermoplastic and a fluorescent compound, wherein the fluorescent compound has a decomposition temperature that establishes a maximum processing temperature for the polymer formulation. The fluorescent compound will thermally decompose to generate gaseous products causing visible bubble formation in the surface of the plastic part in response to exposure to a processing temperature that exceeds the decomposition temperature of the fluorescent compound. If the plastic part was processed without exposure to a processing temperature that exceeds the decomposition temperature of the fluorescent compound, then any fluorescent compound within the plastic part will cause the plastic part to fluoresce in response to exposure to black light. A suitable fluorescent compound may be, for example, selected from oxalates, carbamic acids, carbonic acids, diazocarbonyl compounds, and combinations thereof.

Abstract: In one aspect of the present invention is a blood simulant comprising an aqueous component, a non-aqueous component, a stabilizer, and a red dye soluble in the aqueous component and substantially insoluble in the non-aqueous component. In some embodiments, the blood simulant simulates whole blood or its components. In other embodiments, the simulant simulates bone marrow aspirates or its components. Methods of forming the simulants are also disclosed.

Abstract: According to the present invention, there is provided a method of detecting a complex comprising a membrane protein bound to a therapeutic agent by mass spectrometry. The method comprises: (a) providing a solution comprising a detergent micelle in which said complex is contained; (b) providing a mass spectrometer comprising a nanoelectrospray ionisation source, a mass analyser and a detector; (c) vaporising the solution using the nanoelectrospray ionisation source under conditions such that the complex is released from the micelle; (d) ionising the complex; (e) resolving the ionised complex using the mass analyser; and (f) detecting the resolved complex using the detector. Also provided is a solution comprising a detergent micelle in which a complex is contained, wherein the complex comprises a membrane protein bound to a therapeutic agent.

Abstract: A method and a system is provided for producing one or more matching formulas to match color and coarseness appearance of a target coating on a substrate. The method includes, but is not limited to providing a set of coating chips comprising at least two coating chips having different lightness values, and at least two coating chips having matching lightness values and different coarseness values. A system is also provided for matching color and coarseness appearance of the surface coating.

Abstract: A method and system to detect an improvised explosive device is disclosed. In a particular embodiment, the method includes dispersing a mixture containing a fluorescent material uniformly over a ground cover, illuminating the ground cover with wavelengths of visible light or ultraviolet (UV) light causing the fluorescent material to fluoresce in a visible light spectrum, and detecting where the mixture has been disturbed on the ground cover by visually observing inconsistencies in the fluorescent material on the ground cover that is fluorescing to indicate a location of the improvised explosive device. The method also includes that the mixture is adapted to cling to a person, clothes, or any combination thereof, upon contact.

Abstract: The present invention provides reagents for instrumentation quality control and methods of use thereof. In particular, sets of peptides or other molecules are provided for evaluating the performance of instruments with mass spectrometry (MS) and/or liquid chromatography (LC) functionalities.

Abstract: A living body phantom according to the present invention, which is used as a testing sample in a prepared slide in estimating the performance of a microscope objective lens with the image of the testing sample in the prepared slide acquired by an imaging means via the microscope objective lens and with optical characteristics obtained from the image of the testing sample, includes a non-gel-like solution at least including: a solvent which at least includes water, a refractive index adjustment agent, and a scattering body or which at least includes a refractive index adjustment agent and a scattering body; and a thickener.

Abstract: Methods and arrangements for distinguishing between target areas and non-target areas during a laser surgical procedure involve coating or otherwise providing the non-target areas with a phosphorescent material that emits radiation, upon stimulation when a predetermined condition occurs, that is distinguishable from the treatment radiation.

Abstract: The invention relates to the detection of fatty acids. In a particular aspect, the invention relates to methods for detecting very long chain fatty acids and branched chain fatty acids by mass spectrometry.

Abstract: The disclosure relates to the use of nanoparticles that are coated with unique oligonucleotide (e.g., DNA) sequences of various base lengths (“nano-DNA”) that act as barcodes for product authentication, product serialization, brand protection, track-and-trace, intelligent supply chain, and law enforcement. The nano-DNA can be incorporated into inks, dyes, resins, labels, and other markings at all manufacturing levels, including the product (unit) level, to encode company and product-specific information. The nano-DNA can also be embedded in the product itself during the manufacturing process. Furthermore, the nano-DNA can be quickly, simply, and inexpensively monitored and verified using an electrochemical biosensor device in resource-limited field conditions.

Abstract: According to an example, methods for forming three-dimensional (3-D) nano-particle assemblies include depositing SES elements onto respective tips of nano-fingers, in which the nano-fingers are arranged in sufficiently close proximities to each other to enable the tips of groups of adjacent ones of the nano-fingers to come into sufficiently close proximities to each other to enable the SES elements on the tips to be bonded together when the nano-fingers are partially collapsed. The methods also include causing the nano-fingers to partially collapse toward adjacent ones of the nano-fingers to cause a plurality of SES elements on respective groups of the nano-fingers to be in relatively close proximities to each other and form respective clusters of SES elements, introducing additional particles that are to attach onto the clusters of SES elements, and causing the clusters of SES elements to detach from the nano-fingers.

Abstract: A method includes the steps of blending a first part comprising a low-density fine particulate material additive with a second part comprising original regolith simulant material for producing a lower bulk density blended regolith simulant material having gravity-driven flow properties that resemble those that the original regolith material would have under a reduced gravity of a target extraterrestrial body. The blended regolith simulant material includes one part by volume of original regolith simulant material to N parts by volume of a low-density fine particulate material additive, where N is generally greater than one less than the ratio of the gravitational acceleration on the surface of the earth to the gravitational acceleration on the surface of the target extraterrestrial body.

Abstract: The present invention provides an embedding resin composition for electron microscopy having satisfactory performance as an embedding medium, including embedding performance and sectioning quality, and exhibiting excellent antistatic performance; and a method for observing a sample with an electron microscope using the composition. The embedding resin composition for electron microscopy of the present invention having antistatic performance comprises an ionic liquid and an embedding medium comprising an epoxy-based resin, a methacrylate resin or an unsaturated polyester resin. Preferably, the ionic liquid comprising a quaternary ammonium compound based on the formula (I): and an anion selected from the group consisting of BF4?, PF6?, (CF3SO2)2N?, a halide ion, a conjugate base of carboxylic acid, a conjugate base of sulfonic acid and a conjugate base of an inorganic acid.

Abstract: The present invention relates to a color-changing composition and a multiple-component material including a substrate and a printed layer on the substrate. The printed layer includes a color-changing composition to indicate a change in condition, such as a change in wetness. The color-changing composition includes a matrix-forming component, a leuco dye, a Lewis Acid, a neutral surfactant and an organic solvent.