Luminescent Patents (Class 252/646)
  • Patent number: 11312876
    Abstract: An ink composition is provided. The composition includes a binder material and at least one narrow band emission phosphor being uniformly dispersed throughout the composition, wherein the narrow band emission phosphor has a D50 particle size from about 0.1 ?m to about 15 ?m and is selected from the group consisting of a green-emitting U6+-containing phosphor, a green-emitting Mn2+-containing phosphor, a red-emitting phosphor based on complex fluoride materials activated by Mn4+, and a mixture thereof. A device is also provided.
    Type: Grant
    Filed: January 19, 2021
    Date of Patent: April 26, 2022
    Assignee: GENERAL ELECTRIC COMPANY
    Inventors: Mark D. Doherty, Yangang Liang, Jie Jerry Liu, Samuel Joseph Camardello, James Edward Murphy
  • Patent number: 9011735
    Abstract: Compositions comprising nanosized objects (i.e., nanoparticles) in which at least one observable marker, such as a radioisotope or fluorophore, is incorporated within the nanosized object. The nanosized objects include, for example, metal or semi-metal oxide (e.g., silica), quantum dot, noble metal, magnetic metal oxide, organic polymer, metal salt, and core-shell nanoparticles, wherein the label is incorporated within the nanoparticle or selectively in a metal oxide shell of a core-shell nanoparticle. Methods of preparing the volume-labeled nanoparticles are also described.
    Type: Grant
    Filed: December 30, 2010
    Date of Patent: April 21, 2015
    Assignee: UT-Battelle, LLC
    Inventors: Wei Wang, Baohua Gu, Scott T. Retterer, Mitchel J. Doktycz
  • Patent number: 8697982
    Abstract: A radiation-emitting polymer composition includes a polysiloxane polymer including tritium and a wavelength-shifter chemically bonded as a side chain to the polysiloxane polymer or chemically bonded as a side chain to a siloxane carrier dispersed within the polysiloxane polymer. The wavelength-shifter includes a plurality of cyclic chemical moieties and emits electromagnetic radiation in response to radiation emitted by the tritium.
    Type: Grant
    Filed: October 28, 2013
    Date of Patent: April 15, 2014
    Assignee: LEP America, Incorporated
    Inventors: James W. Smith, Bruce McKague
  • Patent number: 8663820
    Abstract: The invention relates to a printed document of value having at least one authenticity feature in the form of a luminescent substance based on doped host lattices. The host lattice has a strong crystal field and is doped with at least one chromophore with the electron configuration (3d)2.
    Type: Grant
    Filed: March 5, 2002
    Date of Patent: March 4, 2014
    Assignee: Giesecke & Devrient GmbH
    Inventors: Thomas Giering, Rainer Hoppe, Fritz Stahr
  • Patent number: 8569610
    Abstract: A light-emitting polymer composition includes a polysiloxane polymer having tritium that emits radiation and a wavelength-shifter chemically bonded to the polysiloxane polymer or a siloxane carrier dispersed within the polysiloxane polymer. The wavelength-shifter emits light in response to the radiation.
    Type: Grant
    Filed: August 23, 2010
    Date of Patent: October 29, 2013
    Assignee: Power and Light Sources, Incorporated
    Inventors: James W. Smith, Bruce McKague
  • Patent number: 8475681
    Abstract: Neutron scintillating materials are provided, including boron substitution scintillation materials, boron and Li substitution scintillation materials, and Gd-based substitution scintillation materials.
    Type: Grant
    Filed: July 11, 2011
    Date of Patent: July 2, 2013
    Assignee: University of South Carolina
    Inventor: Thomas Vogt
  • Publication number: 20120168671
    Abstract: Compositions comprising nanosized objects (i.e., nanoparticles) in which at least one observable marker, such as a radioisotope or fluorophore, is incorporated within the nanosized object. The nanosized objects include, for example, metal or semi-metal oxide (e.g., silica), quantum dot, noble metal, magnetic metal oxide, organic polymer, metal salt, and core-shell nanoparticles, wherein the label is incorporated within the nanoparticle or selectively in a metal oxide shell of a core-shell nanoparticle. Methods of preparing the volume-labeled nanoparticles are also described.
    Type: Application
    Filed: December 30, 2010
    Publication date: July 5, 2012
    Applicant: UT-BATTELLE, LLC
    Inventors: Wei Wang, Baohua Gu, Scott T. Retterer, Mitchel J. Doktycz
  • Publication number: 20120153243
    Abstract: Neutron scintillating materials are provided, including boron substitution scintillation materials, boron and Li substitution scintillation materials, and Gd-based substitution scintillation materials.
    Type: Application
    Filed: July 11, 2011
    Publication date: June 21, 2012
    Applicant: UNIVERSITY OF SOUTH CAROLINA
    Inventor: Thomas Vogt
  • Publication number: 20120145217
    Abstract: A light-emitting polymer composition includes a polysiloxane polymer having tritium that emits radiation and a wavelength-shifter chemically bonded to the polysiloxane polymer or a siloxane carrier dispersed within the polysiloxane polymer. The wavelength-shifter emits light in response to the radiation.
    Type: Application
    Filed: August 23, 2010
    Publication date: June 14, 2012
    Inventors: James W. Smith, Bruce McKague
  • Patent number: 8177998
    Abstract: The invention is directed to a liquid scintillating composition containing (i) one or more non-polar organic solvents; (ii) (lithium-6)-containing nanoparticles having a size of up to 10 nm and surface-capped by hydrophobic molecules; and (iii) one or more fluorophores. The invention is also directed to a liquid scintillator containing the above composition.
    Type: Grant
    Filed: October 26, 2009
    Date of Patent: May 15, 2012
    Assignee: UT-Battelle, LLC
    Inventors: Sheng Dai, Banu Kesanli, John S. Neal
  • Publication number: 20110147574
    Abstract: Systems and methods for calibrating a nuclear medicine (NM) imaging system are provided that include an NM calibration source. The NM calibration source includes an isotope source having an energy spectrum with at least one energy peak and a fluorescence layer adjacent the isotope source creating at least one additional energy peak in the energy spectrum.
    Type: Application
    Filed: December 23, 2009
    Publication date: June 23, 2011
    Inventors: Ira Blevis, Yaron Hefetz
  • Patent number: 7622532
    Abstract: The present invention relates generally to synthesis of radioactive material, such as a tritiated polymer, and an apparatus for generating electrical current from the nuclear decay process of a radioactive material. In one embodiment, the invention relates to an energy cell (e.g., a battery) for generating electrical current derived from particle emissions occurring within a radioactive material such as a tritiated polymer) on pore walls of a porous semiconductor. The radioactive material may be introduced into the energy cell by a wetting process.
    Type: Grant
    Filed: February 16, 2007
    Date of Patent: November 24, 2009
    Assignees: William Marsh Rice University, BetaBatt, Inc.
    Inventors: Larry L. Gadeken, Paul S. Engel, Kenneth S. Laverdure
  • Patent number: 7572392
    Abstract: Solid-state scintillating compositions for detecting neutrons comprise a Li4Zn(PO4)2 host lattice. Methods of making scintillating compositions comprise: dissolving a lithium-6 precursor and a zinc precursor in a solvent to form a solution; combining phosphoric acid with the solution; combining a base with the solution to form a precipitate; and heating the precipitate to form a Li4Zn(PO4)2 host lattice.
    Type: Grant
    Filed: January 10, 2007
    Date of Patent: August 11, 2009
    Assignee: General Electric Company
    Inventors: Brent Allen Clothier, Sergio Paulo Martins Loureiro, Venkat Subramaniam Venkataramani, Alok Mani Srivastava
  • Patent number: 7501077
    Abstract: Composite scintillator material consisting of a binderless sintered mixture of a Lithium (Li) compound containing 6Li as the neutron converter and Y2SiO5:Ce as the scintillation phosphor, and the use of this material as a method for neutron detection. Other embodiments of the invention include various other Li compounds.
    Type: Grant
    Filed: August 28, 2006
    Date of Patent: March 10, 2009
    Assignee: UT-Battelle, LLC
    Inventors: Jason P. Hodges, M. Lowell Crow, Jr., Ronald G. Cooper
  • Patent number: 6890457
    Abstract: An adhesive containing a far infrared radiation ceramic powder emitting far infrared rays and a radiation source ceramic powder emitting radiations and anions. The radiation source ceramic powder includes silicon dioxide, aluminum oxide, iron oxide, titanium oxide, calcium oxide, magnesium oxide, potassium oxide, sodium oxide and zirconium and/or radium. The adhesive according to the present invention relaxes human beings, helps spontaneous recovery from diseases and improves health by the synergistic effects of far infrared rays, anions and radiations.
    Type: Grant
    Filed: January 14, 2003
    Date of Patent: May 10, 2005
    Inventors: Katsuhiko Umehara, Toshiyuki Waragai
  • Patent number: 6855270
    Abstract: The present invention relates to the use of nanoscintillation systems, or nanoparticles containing fluor molecules, that can be used to detect an electron-emitting or alpha-particle-emitting radioisotope in the absence of organic-solvents commonly used in organic-based liquid scintillation cocktails. The invention also relates to compositions and use of three oil-in-water microemulsion precursors that can be engineered rapidly, reproducibly, and cost-effectively to produce useful nanoparticles less than 100 nanometers.
    Type: Grant
    Filed: June 6, 2002
    Date of Patent: February 15, 2005
    Assignee: The University of Kentucky Research Foundation
    Inventors: Russell J. Mumper, Michael Jay
  • Publication number: 20040178388
    Abstract: The present invention relates to the use of nanoscintillation systems, or nanoparticles containing fluor molecules, that can be used to detect an electron-emitting or alpha-particle-emitting radioisotope in the absence of organic-solvents commonly used in organic-based liquid scintillation cocktails. The invention also relates to compositions and use of three oil-in-water microemulsion precursors that can be engineered rapidly, reproducibly, and cost-effectively to produce useful nanoparticles less than 100 nanometers.
    Type: Application
    Filed: June 6, 2002
    Publication date: September 16, 2004
    Applicant: The University of Kentucky Research Foundation
    Inventors: Russell J. Mumper, Michael Jay
  • Patent number: 6544442
    Abstract: Disclosed is a composition of matter comprising a tributyl phosphate complex of a group 3, lanthanide, actinide, or group 13 salt in an organic carrier and a method of making the complex. These materials are suitable for use in solid or liquid organic scintillators, as in x-ray absorption standards, x-ray fluorescence standards, and neutron detector calibration standards.
    Type: Grant
    Filed: September 22, 1999
    Date of Patent: April 8, 2003
    Assignee: UT-Battelle, LLC
    Inventors: Zane W. Bell, Chuen Huei-Ho, Gilbert M. Brown, Charles Hurlbut
  • Publication number: 20010002246
    Abstract: The present invention relates to a compound based on an alkaline-earth metal, on sulphur and on aluminium, on gallium or indium, to its process of preparation and to its use as luminophore. The compound of the invention corresponds to the formula AB2S4, in which A represents an alkaline-earth metal and B aluminum, gallium, or indium and it is characterized in that it is provided in the form of a powder with a residual oxygen content of not more that 1.5% and composed of particles with a mean size of not more than 10 &mgr;m. This compound is obtained by a process which contains the following stages: a solution or a suspension comprising salts of the elements A and B is formed, the solution or the suspension is dried by atomization and the product obtained in the preceding stages is reacted with carbon disulphide or with a mixture of hydrogen sulphide and or carbon disulphide. The compound of the invention can be used as a luminophore, in particular in cathodoluminescence.
    Type: Application
    Filed: December 15, 2000
    Publication date: May 31, 2001
    Inventors: Denis Huguenin, Pierre MacAudiere
  • Patent number: 5744320
    Abstract: The present invention relates to single and dual-reporter luminescence assays utilizing general and specific reagents to quench enzyme-mediated reactions. In one embodiment of the invention, a reagent is added to the assay which non-specifically quenches enzyme-mediated luminescent reactions. In another embodiment of the invention, a reagent is added to the assay which simultaneously quenches one enzyme-mediated luminescent reaction while activating another distinct enzyme-mediated luminescent reaction. An assay kit containing specific quench reagents, and the reagents themselves are also disclosed.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: April 28, 1998
    Assignee: Promega Corporation
    Inventors: Bruce A. Sherf, Keith V. Wood, Elaine T. Schenborn
  • Patent number: 5714342
    Abstract: The present invention provides for novel reagents whose fluorescence increases in the presence of particular proteases. The reagents comprise a characteristically folded peptide backbone each end of which is conjugated to a fluorophore. When the folded peptide is cleaved, as by digestion with a protease, the fluorophores provide a high intensity fluorescent signal at a visible wavelength. Because of their high fluorescence signal in the visible wavelengths, these protease indicators are particularly well suited for detection of protease activity in biological samples, in particular in frozen tissue sections. Thus this invention also provides for methods of detecting protease activity in situ in frozen sections.
    Type: Grant
    Filed: October 27, 1995
    Date of Patent: February 3, 1998
    Assignee: OncoImmunin, Inc.
    Inventors: Akira Komoriya, Beverly S. Packard
  • Patent number: 5658494
    Abstract: Novel compounds obtainable by reacting together an imido-reagent such as diphenylphosphonimido-triphenylphosphorane), or a phosphine oxide such as p-tolyldiphenylphosphine oxide, with a chelate of a transition or lanthanide or actinide metal, such as tris(dibenzoylmethide)europium III, have the property of fluorescing in UV radiation. The invention includes solid polymer bodies containing such compounds, or chelates of transition or lanthanide or actinide metals generally, the bodies having the property of emitting light or infra-red radiation when subjected to a flux of ultra-violet or ionising radiation by virtue of internally generated, e.g. by tritium ionising radiation. The body is preferably of polystyrene formed by polymerising the monomer in the presence of the compound or metal chelate.
    Type: Grant
    Filed: May 22, 1995
    Date of Patent: August 19, 1997
    Assignee: Amersham International plc
    Inventors: Colin David Bell, John Hewer Coles Howse, Nigel Bosworth, David Martin James
  • Patent number: 5494654
    Abstract: Additives are proposed for compositions comprising radiolabelled organic compounds e.g. 32P-labelled nucleotides. Stabilisers are selected from tryptophan, para-aminobenzoate, indoleacetate and the azole group. Dyes are selected from Sulphorhodamine B, Xylene Cyanol, Azocarmine B and New Coccine. Preferred compositions contain both stabiliser and dye.
    Type: Grant
    Filed: August 23, 1993
    Date of Patent: February 27, 1996
    Assignee: Amersham International plc
    Inventors: Roger M. Price, Christopher C. May, Elizabeth M. Buckley, Timothy Stone
  • Patent number: 5435937
    Abstract: Novel compounds obtainable by reacting together an imido-reagent such as diphenylphosphonimidotriphenylphosphorane) with a chelate of a transition or lanthanide or actinide metal, such as tris(dibenzoylmethide) europium III, has the property of fluorescing in UV radiation. The invention includes solid polymer bodies containing such compounds, or chelates of transition or lanthanide or actinide metals generally, the bodies having the property of emitting light by virtue of internally generated, e.g. by tritium ionising radiation. The body is preferably of polystyrene formed by polymerising the monomer in the presence of the compound or metal chelate.
    Type: Grant
    Filed: February 12, 1993
    Date of Patent: July 25, 1995
    Assignee: Amersham International plc
    Inventors: Colin D. Bell, John H. C. Howse
  • Patent number: 5306445
    Abstract: The invention relates to a composition for the volumetric generation of radiation. The composition comprises a porous substrate loaded with a component capable of emitting radiation upon interaction with an exciting radiation. Preferably, the composition is an aerogel substrate loaded with a component, e.g., a phosphor, capable of interacting with exciting radiation of a first energy, e.g., ultraviolet light, to produce radiation of a second energy, e.g., visible light.
    Type: Grant
    Filed: May 18, 1992
    Date of Patent: April 26, 1994
    Assignee: The United States of America as represented by the United States Department of Energy
    Inventors: Scott Reed, Robert J. Walko, Carol S. Ashley, C. Jeffrey Brinker
  • Patent number: 5240647
    Abstract: The invention provides a process for loading an aerogel substrate with tritium and the resultant compositions. According to the process, an aerogel substrate is hydrolyzed so that surface OH groups are formed. The hydrolyzed aerogel is then subjected to tritium exchange employing, for example, a tritium-containing gas, whereby tritium atoms replace H atoms of surface OH groups. OH and/or CH groups of residual alcohol present in the aerogel may also undergo tritium exchange.
    Type: Grant
    Filed: September 3, 1991
    Date of Patent: August 31, 1993
    Inventors: Carol S. Ashley, C. Jeffrey Brinker, Scott Reed, Robert J. Walko
  • Patent number: 5137659
    Abstract: The invention relates to a composition for the volumetric generation of radiation, wherein a first substance functions as a source of exciting radiation, and a second substance interacts with the exciting radiation to provide a second radiation. The compositions comprise a porous substrate which is loaded with: a source of exciting radiation, a component capable of emitting radiation upon interaction with the exciting radiation, or both. Preferably, the composition is an aerogel substrate loaded with both a source of exciting radiation, such as tritium, and a component capable of interacting with the exciting radiation, e.g., a phosphor, to produce radiation of a second energy.
    Type: Grant
    Filed: March 20, 1990
    Date of Patent: August 11, 1992
    Assignee: The United States of America as represented by the United States Department of Energy
    Inventors: Carol S. Ashley, C. Jeffrey Brinker, Scott Reed, Robert J. Walko
  • Patent number: 5126442
    Abstract: New and useful chromophores have been isolated from the reaction mixture of proteins exposed to reducing sugars in the presence of sulfite over time. The chromophores are believed to be intermediates in nonenzymatic polypeptide glycosylation. The measurement of this chromophore makes possible both qualitative and quantitative assessment of the presence of nonenzymatic browning. Diagnostic and test kits are also disclosed.
    Type: Grant
    Filed: January 8, 1991
    Date of Patent: June 30, 1992
    Assignee: The Rockefeller University
    Inventors: James G. Farmar, Peter Ulrich, Anthony Cerami
  • Patent number: 5122305
    Abstract: The invention relates to a composition for the volumetric generation of radiation, wherein a first substance functions as a source of exciting radiation, and a second substance interacts with the exciting radiation to provide a second radiation. The compositions comprise a porous substrate which is loaded with: a source of exciting radiation, a component capable of emitting radiation upon interaction with the exciting radiation, or both. In the composition, a composite is formed from a carrier material and at least one of the source of the exciting radiation or the component which is capable of interacting with the exciting radiation. The composite is then employed for loading a porous substrate, preferably an aerogel substrate.
    Type: Grant
    Filed: March 20, 1990
    Date of Patent: June 16, 1992
    Inventors: Carol S. Ashley, C. Jeffrey Brinker, Scott Reed, Timothy J. Shepodd, Leroy E. Leonard, Robert E. Ellefson, John T. Gill, Robert J. Walko, Clifford L. Renschler
  • Patent number: 5100587
    Abstract: A new type of RL light source consisting of a zeolite crystalline material, the intralattice spaces of which a tritiated compound and a luminophore are sorbed, and which material is optionally further dispersed in a refractive index-matched polymer matrix.
    Type: Grant
    Filed: December 27, 1990
    Date of Patent: March 31, 1992
    Assignee: The United States of America as represented by the Department of Energy
    Inventors: Roger L. Clough, John T. Gill, Daniel B. Hawkins, Clifford L. Renschler, Timothy J. Shepodd, Henry M. Smith
  • Patent number: 5078919
    Abstract: The invention provides a process for loading an aerogel substrate with tritium and the resultant compositions. According to the process, an aerogel substrate is hydrolyzed so that surface OH groups are formed. The hydrolyzed aerogel is then subjected to tritium exchange employing, for example, a tritium-containing gas, whereby tritium atoms replace H atoms of surface OH groups. OH and/or CH groups of residual alcohol present in the aerogel may also undergo tritium exchange.
    Type: Grant
    Filed: March 20, 1990
    Date of Patent: January 7, 1992
    Assignee: The United States of America as represented by the United States Department of Energy
    Inventors: Carol S. Ashley, C. Jeffrey Brinker, Robert E. Ellefson, John T. Gill, Scott Reed, Robert J. Walko
  • Patent number: 5011781
    Abstract: Disclosed is an improved autoradiography enhancer composition and method of use. The enhancer composition uses an acid anhydride as a dehydration agent.
    Type: Grant
    Filed: July 31, 1989
    Date of Patent: April 30, 1991
    Assignee: Electron Microscope Supplies Corporation
    Inventor: Coleman Bess
  • Patent number: 4997597
    Abstract: A solid state radioluminescent composition for light source comprises an optically clear polymer organic matrix containing tritiated organic materials and dyes capable of "red" shifting primary scintillation emissions from the polymer matrix. The tritiated organic materials are made by reducing, with tritium, an unsaturated organic compound that prior to reduction contains olefinic or alkynylic bonds.
    Type: Grant
    Filed: November 13, 1989
    Date of Patent: March 5, 1991
    Assignee: The United States of America as represented by the United States Department of Energy
    Inventors: Roger L. Clough, John T. Gill, Daniel B. Hawkins, Clifford L. Renschler, Timothy J. Shepodd, Henry M. Smith
  • Patent number: 4889660
    Abstract: A radioluminescent light source comprises a solid mixture of a phosphorescent substance and a tritiated polymer. The solid mixture forms a solid mass having length, width, and thickness dimensions, and is capable of self-support. In one aspect of the invention, the phosphorescent substance comprises solid phosphor particles supported or surrounded within a solid matix by a tritium containing polymer. The tritium containing polymer comprises a polymer backbone which is essentially void of tritium.
    Type: Grant
    Filed: December 24, 1987
    Date of Patent: December 26, 1989
    Assignee: Battelle Memorial Institute
    Inventors: George A. Jensen, David A. Nelson, Peter M. Molton
  • Patent number: 4871480
    Abstract: Disclosed is an improved autoradiography enhancer composition and method of use. The enhancer composition uses an acid anhydride as a dehydration agent.
    Type: Grant
    Filed: November 24, 1987
    Date of Patent: October 3, 1989
    Assignee: Electron Microscope Supplies Corporation
    Inventor: Coleman Bess
  • Patent number: 4710319
    Abstract: The subject invention provides an autofluorography kit composition comprising (i) a first aqueous solution of a water soluble fluor having a formula selected from R--CO.sub.2 --X; R--SO.sub.3 --X; and R--NH.sub.3 --Y; where X and Y are any counterion capable of imparting water solubility, and R is a fluor molecule; and (ii) a second aqueous solution of a precipitator capable of precipitating the water soluble fluor in an electrophoresis gel matrix.
    Type: Grant
    Filed: November 8, 1985
    Date of Patent: December 1, 1987
    Assignee: E. I. Du Pont de Nemours and Company
    Inventors: Duk-Hi Lee, Susan E. Feierberg, Patricia Mayer
  • Patent number: 4624799
    Abstract: A liquid, homogeneous mixture for use in the LSC (Liquid Scintillation Counting) analysis technique, comprising a scintillation liquid, a scintillator and a surfactant, wherein the surfactant includes one or more phosphoric acid esters having formula 1 and/or formula 2 of the sheet of formulae, in which R', R" and R'" represent an organic group, which phosphor acid esters are neutralized to a pH, at which the neutralization product comprises a mono- and/or diphosphate with an alkaline material having a pK.sub.a of at least 5, and in which of the organic phosphoric acid esters having formula 1, R" and R'" may be the same or different.
    Type: Grant
    Filed: September 14, 1984
    Date of Patent: November 25, 1986
    Assignee: Packard Instrument B.V.
    Inventors: Theodorus C. J. M. Hegge, Jan ter Wiel
  • Patent number: 4595599
    Abstract: A luminescent compound, comprising a phosphor group or groups and an alkylalkoxysilane, and a luminescent composition comprising such luminescent compound and a radioactive substance to provide a source of exciting radiation for the luminescent compound in the composition. The present invention further comprises a method for rendering siliceous surfaces luminescent comprising applying the compound or composition to the surface and reacting the compound or composition with water after the compound or composition has migrated into the surface to hydrolyze the compound or composition. The present invention further comprises a luminescent structure having a siliceous surface incorporating the products of the reaction between the surface, water and the compound or composition of the present invention.
    Type: Grant
    Filed: June 21, 1985
    Date of Patent: June 17, 1986
    Assignee: Advanced Chemical Technologies Company
    Inventors: Roy N. Brown, Mike F. Stout, Arnulf P. Hagen, Leo Garwin
  • Patent number: RE45930
    Abstract: The present invention provides for a composition comprising an inorganic scintillator comprising a lanthanide-doped strontium barium mixed halide useful for detecting nuclear material.
    Type: Grant
    Filed: December 12, 2014
    Date of Patent: March 15, 2016
    Assignee: The Regents of The University of California
    Inventors: Gautam Gundiah, Gregory A. Bizarri, Stephen M. Hanrahan, Edith D. Bourret-Courchesne, Stephen E. Derenzo