Methods Of Use Patents (Class 351/246)
  • Patent number: 10735271
    Abstract: Automatic, adaptive stimulus generation includes receiving, at a network device that is associated with a network or system, analytics data that provides an indication of how the network or system is responding to a set of test stimuli introduced into the network or system to facilitate an analysis operation. The network device analyzes the analytics data based on an intended objective for the analysis operation and generates control settings based on the analyzing. The control settings control creation of a subsequent stimulus to be introduced into the network or system during subsequent execution of the analysis operation.
    Type: Grant
    Filed: December 1, 2017
    Date of Patent: August 4, 2020
    Assignee: Cisco Technology, Inc.
    Inventors: Charles Calvin Byers, Joseph Michael Clarke, Gonzalo Salgueiro, M. David Hanes
  • Patent number: 10621432
    Abstract: The present invention provides methods, systems and equipment for acquiring and extracting information using a biological feature. The method for acquiring information using a biological feature—includes: acquiring first data by a terminal; controlling, by the terminal, a light source to generate an intensity-variable light signal according to the first data, and projecting the intensity-variable light signal on an iris; acquiring, by the terminal, first iris information at least comprising first iris contraction information, in which the first iris contraction information is generated by the iris according to the intensity-variable light signal and comprises a first iris contraction activity; acquiring, by the terminal, second iris information at least comprising second iris contraction information; and extracting, by the terminal, second data from the second iris contraction information according to a preset rule.
    Type: Grant
    Filed: November 29, 2016
    Date of Patent: April 14, 2020
    Assignee: TENDYRON CORPORATION
    Inventor: Dongsheng Li
  • Patent number: 10555687
    Abstract: Described herein is an apparatus and method for generating a pain score for a patient. The method includes the steps of generating a PLR response signature for each drug of a plurality of drugs and further initiating a light stimulus to the patient, and measuring a corresponding PLR response. The method includes initiating a neuro-stimulus to the patient, the neuro-stimulus being initiated over a set of frequencies, each frequency being associated with a unique intensity, and stimulating a unique nerve fiber type of the patient, and measuring a PRD response of the patient for the initiated neuro-stimulus. Further, the method includes determining, for each nerve fiber type, a threshold response based on the measured PRD, determining a weight for each threshold response based on the PLR response, and combining the determined weight for each threshold response to obtain a pain score for the patient.
    Type: Grant
    Filed: October 11, 2016
    Date of Patent: February 11, 2020
    Assignee: CHILDREN'S NATIONAL MEDICAL CENTER
    Inventor: Julia C Finkel
  • Patent number: 10551636
    Abstract: The present invention discloses a method for making an aspheric vision correction lens with controlled peripheral defocus. The present invention also discloses a vision correction lens worn outside the eye, an orthokeratology lens and an intraocular lens made according to the method. The present invention further discloses a diagnosis and treatment method that utilizes myopic peripheral defocus to control and retard myopia growth.
    Type: Grant
    Filed: July 22, 2016
    Date of Patent: February 4, 2020
    Assignee: EYEBRIGHT MEDICAL TECHNOLOGY (BEIJING) CO., LTD.
    Inventors: Zhao Wang, Jiangbing Xie
  • Patent number: 10463473
    Abstract: An accommodating intraocular lens with variable optical power, comprising at least two optical elements, at least one of which is movable relative to the other in a direction perpendicular to the optical axis, wherein the optical elements form a lens with different optical power at different relative positions of the optical elements. At least two of the optical elements of the lens comprise at least one additional optical correction surface, which correction surfaces are adapted for simultaneous variable correction of one or more optical aberrations of the natural eye in which the degree of correction depends on the relative position of the optical elements.
    Type: Grant
    Filed: December 13, 2007
    Date of Patent: November 5, 2019
    Assignee: Akkolens International B.V.
    Inventors: Michiel Christiaan Rombach, Aleksey Nikolaevich Simonov
  • Patent number: 10463249
    Abstract: An eye movement-based methodology and assessment tool may be used to quantify many aspects of human dynamic visual processing using a relatively simple and short oculomotor task, noninvasive video-based eye tracking, and validated oculometric analysis techniques. By examining the eye movement responses to a task including a radially-organized appropriately randomized sequence of Rashbass-like step-ramp pursuit-tracking trials, distinct performance measurements may be generated that may be associated with, for example, pursuit initiation (e.g., latency and open-loop pursuit acceleration), steady-state tracking (e.g., gain, catch-up saccade amplitude, and the proportion of the steady-state response consisting of smooth movement), direction tuning (e.g., oblique effect amplitude, horizontal-vertical asymmetry, and direction noise), and speed tuning (e.g., speed responsiveness and noise). This quantitative approach may provide fast and results (e.g.
    Type: Grant
    Filed: August 14, 2017
    Date of Patent: November 5, 2019
    Assignee: United States of America as Represented by the Administrator of NASA
    Inventors: Leland Stone, Dorion Liston
  • Patent number: 10448819
    Abstract: The present invention relates generally to lens design and, more particularly, to a method for designing, evaluating and optimizing ophthalmic lenses and laser vision correction in order to optimally manage issues resulting from, or related to, halos.
    Type: Grant
    Filed: November 14, 2013
    Date of Patent: October 22, 2019
    Assignee: AMO Groningen B.V.
    Inventor: Hendrik A. Weeber
  • Patent number: 10409146
    Abstract: A terminal device (300) includes a projection target holding unit that holds projection information to be projected by an image projection device (200), a storage unit that stores position information indicating a position on the retina of a user (P) at which the projection information is to be projected, a position information acquisition unit that acquires the position information from the storage unit, an image data generation unit that generates image data (D) of an image (202G) that projects the projection information at the position indicated by the position information, and an image output processing unit that outputs the image data (D) to the image projection device (200).
    Type: Grant
    Filed: June 8, 2017
    Date of Patent: September 10, 2019
    Assignee: QD Laser, Inc.
    Inventors: Mitsuru Sugawara, Makoto Suzuki, Kinya Hasegawa
  • Patent number: 10402644
    Abstract: Embodiments are disclosed for using an apparatus to perform pupil identification. An example method includes measuring, by a light sensor of the apparatus, an ambient infrared light level. The example method further includes determining whether the measured ambient infrared light level exceeds a threshold level. The example method further includes performing pupil identification on a user based on the determination of whether the measured ambient infrared light level exceeds the threshold level. In this regard, the example method involves performing bright pupil identification in an instance in which the measured ambient infrared light level exceeds the threshold level, and performing dark pupil identification if not. Corresponding apparatuses and non-transitory computer readable storage media are also provided.
    Type: Grant
    Filed: October 24, 2017
    Date of Patent: September 3, 2019
    Assignee: WELLS FARGO BANK, N.A.
    Inventor: Masoud Vakili
  • Patent number: 10304120
    Abstract: The present invention provides a merchandise sales service device based on dynamic scene change, a merchandise sales system based on dynamic scene change, a method for selling merchandise based on dynamic scene change, and a non-transitory computer readable storage medium having computer program recorded thereon. That is, it is possible to transmit information about a commodity and image information of the commodity to user equipment by efficiently configuring images and dynamically changing the images in a commodity purchase procedure. Accordingly, a user can acquire detailed information about a commodity and carefully purchase the commodity, similar to actually purchasing the commodity at an offline store. Further, it is possible to reduce the rate of returning of purchased commodities for the seller of the commodities.
    Type: Grant
    Filed: September 22, 2015
    Date of Patent: May 28, 2019
    Assignee: ELEVEN STREET CO., LTD.
    Inventors: Seong Hoon Jeong, Sung Bak Baek
  • Patent number: 10281742
    Abstract: A contact lens and a method for treating an eye with myopia is described. The contact lens includes an inner optic zone and an outer optic zone. The outer optic zone includes at least a portion with a first power, selected to correct distance vision. The inner optic zone has a relatively more positive power (an add power). In some embodiments the add power is substantially constant across the inner optic zone. In other embodiments the add power is variable across the inner optic zone. While in some embodiments the inner optic zone has a power designed to substantially eliminate lag of accommodation in the eye with myopia, in other embodiments, the add power may be higher.
    Type: Grant
    Filed: October 18, 2016
    Date of Patent: May 7, 2019
    Assignee: Brien Holden Vision Institute Limited
    Inventors: Brien Anthony Holden, Gregor Schmid, Padmaja Rajagopal Sankaridurg, Arthur Ho, Aldo Abraham Martinez Mangos, Percy Fabian Lazon, Earl Leo Smith, III
  • Patent number: 10258231
    Abstract: A method of processing a 3D OCT dataset is present. A method according to some embodiments of the present invention includes obtaining an OCT data from the 3D OCT dataset; obtaining an OCTA data from the 3D OCT dataset; performing segmentation for at least one boundary on the OCT data; processing the OCTA data in a region of interest to create at least one image representation by assigning a value to each pixel of each of the image representation; and displaying at least one image representation.
    Type: Grant
    Filed: December 30, 2015
    Date of Patent: April 16, 2019
    Assignee: OPTOVUE, INC.
    Inventors: Jay Wei, Tony H. Ko, Yi-Sing Hsiao, Ben Jang, Richard Rosen
  • Patent number: 10251545
    Abstract: A process for assessing at least one characteristic of a user's vision includes determining a characteristic of at least one camera of a mobile device; using the at least one camera, capturing at least one image of an object; determining, with reference to a portion of the at least one image composed of the object, a distance from the mobile device to the object at a time of capture of the at least one image; and receiving input from the user in response to material presented on the object.
    Type: Grant
    Filed: November 15, 2016
    Date of Patent: April 9, 2019
    Assignee: JAND, INC.
    Inventors: Joseph Carrafa, Molly Rhodes
  • Patent number: 10159407
    Abstract: An anterior eye tomographic image capturing apparatus determining a power of an IOL (intraocular lens) is configured to acquire a tomographic image of an anterior eye along a straight line passing through a corneal apex of the anterior eye; identify a corneal apex position of the anterior eye, an equator position of a crystalline lens of the anterior eye, and a SS (scleral spur) position of the anterior eye based on the tomographic image; calculate an ELP (estimated lens position) based on a first distance from the corneal apex position to the SS position in a direction of a visual axis and a second distance from the SS position to the equator position in the direction of the visual axis; and determine the power of the IOL by using the ELP.
    Type: Grant
    Filed: October 18, 2016
    Date of Patent: December 25, 2018
    Assignee: Tomey Corporation
    Inventors: Fushi Li, Keiichiro Okamoto, Kenichi Hayashi
  • Patent number: 10111583
    Abstract: Techniques related to vision correction are disclosed. The techniques involve establishing a visual model associated with a patient. The visual model includes data related to a quality of the patient's vision. A boundary is established as a function of the data associated with the visual model. The boundary is indicative of an area to be corrected within the patient's vision. A retinal map is established as a function of the boundary. An image from a camera associated with the patient is captured and corrections are applied to the image based on the retinal map to generate a corrected image. The corrected image is presented to the eye of the patient.
    Type: Grant
    Filed: March 29, 2018
    Date of Patent: October 30, 2018
    Assignee: Raytrx, LLC
    Inventors: Richard C. Freeman, Michael H. Freeman, Mitchael C. Freeman, Chad Boss, Jordan Boss
  • Patent number: 10110983
    Abstract: An ear measurement system and method include obtaining an image of an ear and an associated a calibration device, and analyzing the image to determine the size of desired portions of the ear. Such sizing is then used, for example, for fitting an earbud or earbud adapter.
    Type: Grant
    Filed: February 17, 2012
    Date of Patent: October 23, 2018
    Assignee: Harman International Industries, Incorporated
    Inventors: Seth Burgett, Richard J. Daniels, David Fishbaine, Bharat Rajaram, Michael D. Wetle, Tonya An
  • Patent number: 10088384
    Abstract: A system and method of characterizing through-focus visual performance of an IOL using metrics based on an area under the modulation transfer function for different spatial frequencies at different defocus positions of the IOL. Also disclosed is a system and method of characterizing through-focus visual performance of an IOL using a metric based on an area under a cross-correlation coefficient for an image of a target acquired by the IOL at different defocus positions of the IOL.
    Type: Grant
    Filed: November 17, 2017
    Date of Patent: October 2, 2018
    Assignee: AMO Groningen B.V.
    Inventors: Aixa Alarcon Heredia, Carmen Canovas Vidal, Robert Rosén, Hendrik A. Weeber, Patricia Ann Piers
  • Patent number: 10058243
    Abstract: Systems and methods are provided for evaluating an eye of a patient from a set of OCT data. A layer segmentation component is configured to identify and segment a plurality of retinal layers within the set of OCT data. The plurality of layers include a layer of interest. A mapping component is configured to generate at least one of an en face representation of the layer of interest and a three-dimensional reconstruction of the layer of interest from the segmented plurality of layers. A parameter generator is configured to derive at least one parameter, representing a thickness of the layer of interest, from the at least one of the en face representation of the layer of interest and the three-dimensional reconstruction of the layer of interest. A user interface is configured to provide the determined at least one parameter to a display.
    Type: Grant
    Filed: February 25, 2016
    Date of Patent: August 28, 2018
    Assignee: The Cleveland Clinic Foundation
    Inventors: Justis P. Ehlers, Sunil Srivastava
  • Patent number: 10055495
    Abstract: The invention generally relates to computer implemented systems and methods for utilizing detection of eye movements in connection with interactive graphical user interfaces and, in particular, for utilizing eye tracking data to facilitate and improve information search and presentation in connection with interactive graphical user interfaces. A gaze search index is determined based on information that has been presented on an information presentation area and gaze data signals. The gaze search index comprises links between gaze search parameters and presented information that satisfies gaze filter criteria for respective gaze search parameter. A user can initiate query searches for information on the computer device or on information hosts connectable to the computer device via networks by using combinations of gaze search parameters of the gaze search index and non gaze search parameters of a non gaze search index.
    Type: Grant
    Filed: October 29, 2012
    Date of Patent: August 21, 2018
    Assignee: Tobii AB
    Inventors: Anders Olsson, Mårten Skogö
  • Patent number: 10045690
    Abstract: A method for determining wave-front aberration data of a to-be-tested optical system comprising the steps of: a) providing a wave-front sensing image of light received from the tested optical system; b) providing a model representative of the optical system with at least an optical parameter representative of said model; and c) optimizing a set of wave-front coefficient data and said at least optical parameter of said model according to a merit function calculating the merit function comprises the steps of generating a wave-front sensing modeled image of light received from said model by the at least optical parameter and the set of wave-front coefficient data, and calculating a criteria based on shape parameter data of the wave-front sensing image and shape parameter data of the wave-front sensing modeled image, so as to obtain wave-front aberration data of the tested optical system.
    Type: Grant
    Filed: June 9, 2014
    Date of Patent: August 14, 2018
    Assignee: Essilor International
    Inventors: Martha Hernandez Castanedas, Gildas Marin, Larry Thibos, Tao Liu
  • Patent number: 10042181
    Abstract: A method for estimating and tracking refractive error progression of an individual includes estimating a percentile of Spherical Equivalent Refraction (SPHEQ) as a function of at least the individual's age by comparison to a reference population; estimating an expected SPHEQ trajectory over a future predetermined period of time; comparing the expected SPHEQ trajectory with the reference population; and comparing the expected SPHEQ trajectory with an expected SPHEQ trajectory using an ametropia control treatment, thereby showing a possible treatment benefit over the predetermined period of time.
    Type: Grant
    Filed: January 27, 2016
    Date of Patent: August 7, 2018
    Assignee: Johnson & Johnson Vision Care, Inc.
    Inventors: Noel A. Brennan, Khaled Chehab, Eric R. Ritchey, Lisa A. Jones-Jordan, Loraine T. Sinnott, Xu Cheng
  • Patent number: 10032429
    Abstract: A computing device includes an interface configured to receive image data that is indicative of a field-of-view (FOV) that is associated with a head-mountable display (HMD). The computing device also includes a computing system configured to determine optical flow from the image data and to determine, based on the optical flow, whether or not the HMD is associated with operation of a vehicle. Further, the computing device is configured to control the HMD to display information in a first mode, if the HMD is associated with the operation of the vehicle, and to control the HMD to display information in a second mode, if the HMD is not associated with the operation of the vehicle.
    Type: Grant
    Filed: January 4, 2016
    Date of Patent: July 24, 2018
    Assignee: Google LLC
    Inventors: Thad E. Starner, Michael P. Johnson
  • Patent number: 10022048
    Abstract: Method, system and computer program for measuring light diffusion in the eyeball or in the ocular region. The method comprises: projecting a punctiform light beam onto the retina; correcting low-order ocular aberrations of the eye; capturing and recording an image of the retinal plane formed after reflection of the punctiform light beam on the retina and a double passage through the ocular media of the eye; and at the same time as capturing the image of the retinal plane, performing a high- and low-order ocular aberration measurement in the plane of the pupil and performing a light diffusion measurement, combining ocular aberration measurement information with information on the image of the retinal plane. The system and the computer program are adapted for implementing the method.
    Type: Grant
    Filed: July 29, 2015
    Date of Patent: July 17, 2018
    Assignee: UNIVERSITAT POLITECNICA DE CATALUNYA
    Inventors: Jaume Pujol Ramo, Montserrat Arjona Carbonell, Carlos Enrique Garcia Guerra, Mikel Aldaba Arévalo, Meritxell Vilaseca Ricart, Fernando Díaz Doutón
  • Patent number: 9986906
    Abstract: Embodiments of this invention relate to the generation of wavefronts for measurements, diagnostics, and treatment planning for ophthalmic applications. In some embodiments, a wavefront generator generates light having a uniform wavefront, which is focusable on the retina of an emmetropic eye by the normal function of the emmetropic eye. In some embodiments, the wavefront generator can generate light having a custom wavefront which is not focusable on the retina of the emmetropic eye. In some embodiments, the wavefront generator can receive information relating to an optical aberration of the eye, generate a custom wavefront, and project light having this custom wavefront, which in combination with the optical aberration of the eye is focusable on the retina.
    Type: Grant
    Filed: November 17, 2016
    Date of Patent: June 5, 2018
    Assignee: AMO Groningen B.V.
    Inventor: Theophilus Bogaert
  • Patent number: 9962071
    Abstract: System and method directed towards providing full and even illumination of a patient's retina through lighting integrated into a handheld fundus lens. By integrating the lighting, the method and system reduces and even eliminate many lens artifacts and reflections. By increasing the accuracy, quality, and field of view afforded during clinical examination of the retina, the method and system will allow practitioners to make more accurate diagnoses and will increase safety during retinal surgical procedures.
    Type: Grant
    Filed: October 12, 2015
    Date of Patent: May 8, 2018
    Assignee: University of Virginia Patent Foundation
    Inventor: Paul Andrew Yates
  • Patent number: 9940589
    Abstract: Embodiments of the invention include a virtual reality system that includes an instrumented device used to present a virtual shopping environment to a simulation participant. The participant's interactions with the virtual shopping environment may be used to conduct market research into the consumer decision making process. The virtual shopping environment may include one or more smart objects configured to be responsive to participant interaction. The virtual shopping environment may recreate a real-world shopping environment.
    Type: Grant
    Filed: December 29, 2007
    Date of Patent: April 10, 2018
    Assignee: RED DOT SQUARE SOLUTIONS LIMITED
    Inventor: Mark Edwards
  • Patent number: 9833139
    Abstract: Apparatus and methods are described for performing structure measurement on a tear film of an eye of a subject. At least a portion of a surface of the tear film is illuminated using a broadband light source. A spectrum of light of the broadband light that is reflected from at least one point of the tear film is measured, using a spectrometer. Color information for a plurality of points of the tear film is obtained, by imaging a field of view of the tear film using a color camera. Using a processing unit, data from the color camera and data from the spectrometer that are indicative of characteristics of the tear film are received, and based upon a combination of the data received from the color camera and the data received from the spectrometer, an output is generated that is indicative of a structure of the tear film.
    Type: Grant
    Filed: August 8, 2017
    Date of Patent: December 5, 2017
    Assignee: ADOM, Advanced Optical Technologies Ltd.
    Inventors: Yoel Arieli, Yoel Cohen, Shlomi Epstein, Dror Arbel, Ra'anan Gefen
  • Patent number: 9826899
    Abstract: Methods and devices are provided to obtain refractive correction with superior visual acuity (e.g., 20/10) by achieving an astigmatism-free customized refractive correction. The astigmatism-free customized refractive correction involves obtaining an objective and precise measurement of cylindrical power in a resolution between 0.01 D and 0.10 D in an eye using an objective aberrometer, reliably relating the cylindrical axis obtained from the objective aberrometer to that in a phoroptor, determining an optimized focus error of an eye through subjective refraction with a phoroptor, generating a customized refraction by combining the objective measured cylindrical power, the objective measured cylindrical axis, and the subjectively measured focus power, fabricating a custom lens with a tolerance finer than 0.09 D based on the generated customized refraction, and delivering an ophthalmic lens that can provide an astigmatism-free refractive correction for an eye.
    Type: Grant
    Filed: April 29, 2016
    Date of Patent: November 28, 2017
    Assignee: PERFECT VISION TECHNOLOGY (HK) LTD.
    Inventor: Junzhong Liang
  • Patent number: 9798382
    Abstract: Methods and systems to facilitate eye tracking data analysis are provided. Point of regard information from a first client device of a first user is received, where the point of regard information is determined by the first client device by detecting one or more eye features associated with an eye of the first user. The point of regard information is stored. A request to access the point of regard information is received, and the point of regard information is sent in response to the request, where the point of regard information is used in a subsequent operation.
    Type: Grant
    Filed: April 16, 2014
    Date of Patent: October 24, 2017
    Assignee: Facebook, Inc.
    Inventors: Sune Alstrup Johansen, Henrik Hegner Tomra Skovsgaard, Martin Henrik Tall, Javier San Agustin Lopez, Sebastian Sztuk
  • Patent number: 9778021
    Abstract: An efficient method of evaluating the level of contrast of an OCT dataset is presented. The method develops a metric to segregate useful and not-so-useful data in one or more OCT B-scans, in order to reduce spurious subsequent analyses of the data by downstream segmentation algorithms. It is designed to be fast and efficient and is applied to determining autofocus of an OCT instrument real-time and in identifying a real image from its complex conjugate twin.
    Type: Grant
    Filed: August 22, 2014
    Date of Patent: October 3, 2017
    Assignee: CARL ZEISS MEDITEC, INC.
    Inventor: Homayoun Bagherinia
  • Patent number: 9763568
    Abstract: A method of evaluating the efficiency of a myopia control product for a wearer, the method comprising: an initial myopia indicator providing step S1, during which the initial value of a myopia indicator of the wearer is provided, a myopia condition step S2, during which the wearer using the myopia control product is placed in myopia inducing conditions, a resulting myopia indicator determining step S3, during which the resulting value of the myopia indicator of the wearer is determined after the wearer has been placed in the myopia inducing conditions, an efficiency evaluation step S4, during which the efficiency of the myopia control product is evaluated by comparing the initial value of the myopia indicator and the resulting value of the myopia indicator.
    Type: Grant
    Filed: February 26, 2014
    Date of Patent: September 19, 2017
    Assignee: ESSILOR INTERNATIONAL (COMPGNIE GENERALE D'OPTIQUE)
    Inventor: Björn Drobe
  • Patent number: 9720253
    Abstract: Certain embodiments of the present invention are directed to therapeutic intervention in patients with eye-length-related disorders to prevent, ameliorate, or reverse the effects of the eye-length-related disorders. Embodiments of the present invention include methods for early recognition of patients with eye-length-related disorders, therapeutic methods for inhibiting further degradation of vision in patients with eye-length-eye-length-related disorders, reversing, when possible, eye-length-related disorders, and preventing eye-length-related disorders. Additional embodiments of the present invention are directed to particular devices used in therapeutic intervention in patients with eye-length-related disorders.
    Type: Grant
    Filed: December 21, 2009
    Date of Patent: August 1, 2017
    Assignee: THE MEDICAL COLLEGE OF WISCONSIN
    Inventors: Jay Neitz, Maureen Neitz
  • Patent number: 9662006
    Abstract: Methods and systems for obtaining an ocular aberration measurement of an eye of a patient are provided. Exemplary techniques involve obtaining a first induced metric for the eye that corresponds to a first accommodation state of the eye, obtaining a second induced metric for the eye that corresponds to a second accommodation state of the eye, and determining a natural metric of the eye based on the first and second induced metrics. An induced metric may include a pupil size or a spherical aberration. Techniques can also include determining a target metric for the eye base on the natural metric, determining whether an actual metric of the eye meets the target metric, obtaining an ocular aberration measurement of the eye if the actual metric meets the target metric, and determining a treatment for the eye based on the ocular aberration measurement.
    Type: Grant
    Filed: June 7, 2016
    Date of Patent: May 30, 2017
    Assignee: AMO Development, LLC
    Inventors: Guang-ming Dai, Leander Zickler
  • Patent number: 9662012
    Abstract: The invention is directed to quantification of the effects of drugs on a patient using pupillometric measures. Apparatus and processes for obtaining control and patient measures and deriving relationships from same are provided. The methods of the invention provide doctor quantitative feedback on patient symptoms and on the effects of a drug or dosage of same on a patient, as well as provide assessment capability to patients and law enforcement.
    Type: Grant
    Filed: March 2, 2016
    Date of Patent: May 30, 2017
    Assignee: Drexel University
    Inventor: Robert A. Hirsh
  • Patent number: 9658468
    Abstract: Wavefront measurements of eyes are often taken when the pupil is in a first configuration in an evaluation context. The results can be represented by a set of basis function coefficients. Prescriptive treatments are often applied in a treatment context, which is different from the evaluation context. Hence, the patient pupil can be in a different, second configuration, during treatment. Systems and methods are provided for determining a transformed set of basis function coefficients, based on a difference between the first and second configurations, which can be used to establish the vision treatment.
    Type: Grant
    Filed: May 13, 2015
    Date of Patent: May 23, 2017
    Assignee: AMO Development, LLC
    Inventor: Guang-ming Dai
  • Patent number: 9655512
    Abstract: This invention discloses methods and systems for measuring corneal epithelial thickness and power, stromal thickness, subepitheila corneal power and topography. The systems and methods disclosed herein are non-invasive, non-contact and automated imaging methods which preferably makes use of Fourier-domain optical tomography. Also disclosed herein are scanning patterns and image analysis methods for utilizing and analyzing Fourier-domain optical coherence tomography images to obtain information about conical epithelial and stromal properties as well as parameters useful for evaluating the properties. The methods and systems described herein are useful as eye disease diagnostic tools and eye surgery planning tools.
    Type: Grant
    Filed: April 6, 2012
    Date of Patent: May 23, 2017
    Assignee: UNIVERSITY OF SOUTHERN CALIFORNIA
    Inventors: David Huang, Yan Li, Ou Tan, Maolong Tang
  • Patent number: 9655511
    Abstract: An apparatus and method to improve the prescribing of customized ophthalmic corrections which contain higher order aberration. The apparatus enables the subjective measurement of higher order aberrations such as spherical aberration which can be used as part of the prescription for customized ophthalmic corrections.
    Type: Grant
    Filed: June 25, 2015
    Date of Patent: May 23, 2017
    Assignee: Johnson & Johnson Vision Care, Inc.
    Inventors: Bruce M. Pixton, John E. Greivenkamp, Gregory A. Williby, Russell Spaulding
  • Patent number: 9658470
    Abstract: Provided herein is a computer program product comprising a non-transitory computer-readable medium storing an algorithm to optimize a wavefront guided correction for a custom ophthalmic lens. The correction is determined from inputs of quantified wavefront error and registration uncertainty and a metric predictive of a visual performance task of interest and provides a level of visual performance within a user-defined performance range. Also provided is a method for optimizing a wavefront guided correction for a custom ophthalmic lens via inputting residual wavefront error values and quantified translational and rotational movements into an algorithm configured to determine the optimal wavefront guided correction therefrom and a custom ophthalmic lens comprising the correction.
    Type: Grant
    Filed: February 27, 2014
    Date of Patent: May 23, 2017
    Assignee: University of Houston System
    Inventors: Raymond A. Applegate, Jason D. Marsack, Konrad Pesudovs, Yue Shi
  • Patent number: 9649027
    Abstract: A device for determining biometric variables of the eye, as are incorporated in the calculation of intraocular lenses including a multi-point keratometer and an OCT arrangement. The keratometer measurement points are illuminated telecentrically and detected telecentrically and the OCT arrangement is designed as a laterally scanning swept-source system with a detection region detecting the whole eye over the whole axial length thereof. The multi-point keratometer ensures that a sufficient number of keratometer points are available for measuring the corneal surface. By contrast, telecentricity ensures that the positioning inadequacies of the measuring instrument in relation to the eye to be measured do not lead to a local mismatch of the reflection points. The swept-source OCT scan detects the whole eye over the length thereof so that both anterior chamber structures and retina structures can be detected and a consistent whole eye image can be realized.
    Type: Grant
    Filed: September 27, 2013
    Date of Patent: May 16, 2017
    Assignee: Carl Zeiss Meditec AG
    Inventors: Ralf Ebersbach, Martin Hacker, Gerard Antkowiak, Peter Klopfleisch, Ferid Bajramovic, Tobias Bühren, Matthias Reich
  • Patent number: 9645412
    Abstract: A system and method for identifying a custom contact lens for a patient. The method includes receiving as input results from a bare eye examination of a patient including at least a measured sphere power; receiving as input a target or actual measured sphere power of a selected fitting lens; receiving as input results of an over-refraction examination of a patient wearing the fitting lens, wherein the results of the over-refraction examination include at least a measured sphere power; calculating the power delivered by the fitting lens on the patient's eye based on input received from the bare eye examination and over-refraction examinations; calculating an Effectiveness Ratio using the calculated power delivered by the fitting lens and the target or actual measured sphere power of the fitting lens; and calculating a custom lens power for the patient using the Effectiveness Ratio and measured sphere power from the bare eye examination.
    Type: Grant
    Filed: November 5, 2014
    Date of Patent: May 9, 2017
    Assignee: Johnson & Johnson Vision Care Inc.
    Inventors: Christopher Wildsmith, Michael F Widman
  • Patent number: 9591967
    Abstract: An optical tomographic imaging device configured to acquire a tomographic image of a tissue of an object, includes: a dividing device configured to divide a light beam emitted from a light source into measurement light and reference light; a combining device configured to combine the measurement light, which is separated by the dividing device and is reflected from the tissue, with the reference light so as to generate interference light for acquiring the tomographic image; a plurality of irradiation devices, each of the plurality of irradiation devices being configured to guide the measurement light and irradiate the tissue with the measurement light: and a switching device configured to switch the plurality of irradiation devices from one to another and select one of the plurality of irradiation devices to cause the selected irradiation device to irradiate the measurement light output from the dividing device with tissue.
    Type: Grant
    Filed: September 25, 2015
    Date of Patent: March 14, 2017
    Assignee: NIDEK CO., LTD.
    Inventors: Junpei Nishiyama, Yukihiro Higuchi
  • Patent number: 9581834
    Abstract: Systems and methods for providing enhanced image quality across a wide and extended range of foci encompass vision treatment techniques and ophthalmic lenses such as contact lenses and intraocular lenses (IOLs). Exemplary IOL optics can include a circular surface structure which acts as a diffractive or phase shifting profile. In some cases, a single ring IOL includes an anterior face and a posterior face, where a profile can be imposed on the anterior or posterior surface or face. The profile can have an inner portion such as a microstructure or central echelette, and an outer portion. Between the inner portion and the outer portion, there may be a transition zone that connects the inner and outer portions.
    Type: Grant
    Filed: January 5, 2015
    Date of Patent: February 28, 2017
    Assignee: AMO Groningen B.V.
    Inventor: Hendrik A. Weeber
  • Patent number: 9566002
    Abstract: To ensure display of a region of interest on a fundus image and a tomographic image of an eye to be inspected in a correspondence manner, an apparatus for processing images of an eye to be inspected includes: a unit that acquires a fundus image of an eye to be inspected; a unit that designates an arbitrary point on the fundus image; a unit that acquires a tomographic image of the eye to be inspected; a unit that calculates a point on the tomographic image corresponding to the arbitrary point; and a unit that converts a coordinate system for displaying the tomographic image and the fundus image in association with each other on the basis of positions of the arbitrary point and the corresponding point.
    Type: Grant
    Filed: January 22, 2013
    Date of Patent: February 14, 2017
    Assignee: CANON KABUSHIKI KAISHA
    Inventors: Yasuhiro Nakahara, Shigeaki Ono, Yukio Sakagawa, Hiroki Uchida
  • Patent number: 9560963
    Abstract: Methods for performing a surgical procedure using optical coherence tomography (OCT) are provided. The method includes extracting lenticular material from within a capsular bag of an eye of a patient; acquiring at least one OCT image of an interior region of the capsular bag after extraction of substantially all of the lenticular material from within the capsular bag; determining from the at least one OCT image the presence of cellular debris remaining within the interior of the capsular bag; and extracting at least a portion of the remaining cellular debris from the interior of the capsular bag.
    Type: Grant
    Filed: August 25, 2015
    Date of Patent: February 7, 2017
    Assignee: Bioptigen, Inc.
    Inventors: Eric L. Buckland, Al-Hafeez Dhalla, Robert H. Hart
  • Patent number: 9501621
    Abstract: Treatment validation techniques include generating a modified treatment target from an original treatment target using a modification process, and comparing induced aberrations provided by the original and modified treatment targets, so as to verify the modified treatment target or the modification process. In some cases, a modification process may include a deconvolution process, a low pass filter process, a scaling process, or an adjustment process. The induced aberrations may include high order aberrations, such as spherical aberration.
    Type: Grant
    Filed: November 7, 2014
    Date of Patent: November 22, 2016
    Assignee: AMO Development, LLC
    Inventors: Guang-ming Dai, Anatoly Fabrikant, Dimitri Chernyak, Jayesh Shah
  • Patent number: 9492081
    Abstract: Embodiments of the present invention provide a retinal densitometer, comprising an illumination unit for outputting bleaching illumination for photo-bleaching an eye and reflectance illumination at one or more wavelengths for determining reflectance of the eye at the one or more wavelengths, an imaging device arranged to output image data corresponding to an image of the eye at the one or more wavelengths of reflectance illumination, and a control unit arranged to control the illumination unit and the imaging device to output the bleaching illumination, the reflectance illumination at the one or more wavelengths and to output image data according to a predetermined sequence.
    Type: Grant
    Filed: April 5, 2013
    Date of Patent: November 15, 2016
    Assignee: The Science and Technology Facilities Council
    Inventors: David Henry, Tom Margrain, Alison Binns, David Atkinson, Stephen Todd
  • Patent number: 9468369
    Abstract: A system includes a model eye and an optical measurement instrument, which includes: a corneal topography subsystem; a wavefront sensor subsystem; and an eye structure imaging subsystem. The subsystems may have a common fixation axis, and be operatively coupled to each other via a controller. The optical measurement instrument may perform measurements of the model eye to verify correct operation of the optical measurement instrument for measuring one or more characteristics of a subject's eye. The model eye may include an optically transmissive structure having a front curved surface and an opposite rear planar surface, and a material structure provided at the rear planar surface of the optically transmissive structure and having a characteristic to cause a speckle pattern of a portion of a coherent light beam that is directed back out the front curved surface of the optically transmissive structure to have a bright-to-dark ratio of less than 2:1.
    Type: Grant
    Filed: December 3, 2014
    Date of Patent: October 18, 2016
    Assignee: AMO WaveFront Sciences, LLC
    Inventors: Richard J. Copland, Daniel R. Neal, Thomas D. Raymond, Wei Xiong, Paul D. Pulaski, Stephen W. Farrer, Carmen Canovas Vidal, Daniel R. Hamrick
  • Patent number: 9445890
    Abstract: Apparatus for performing intraocular implant surgery, including surgical apparatus for performing intraocular implant surgery, an autorefraction device associated with the surgical apparatus, wherein the autorefraction device is configured to perform autorefraction on the aphakic eye to provide one or more aphakic refraction measurements, and a processor connected to the autorefraction device, wherein the processor is configured to process the aphakic refraction measurements and provide the user of the apparatus with information regarding the power of the intraocular lens.
    Type: Grant
    Filed: December 5, 2013
    Date of Patent: September 20, 2016
    Assignee: WaveTec Vision Systems, Inc.
    Inventor: Tsontcho Ianchulev
  • Patent number: 9427144
    Abstract: Described herein are methods and systems for detecting anisocoria and evaluating an underlying disease causing anisocoria.
    Type: Grant
    Filed: January 5, 2015
    Date of Patent: August 30, 2016
    Assignee: Ophthalmx LLC
    Inventor: Brian Peck
  • Patent number: 9345621
    Abstract: Systems and methods related to corneal ablation for treatment of one or more high-order optical aberrations are provided. A method includes providing a defect-correcting prescription, determining an ablation profile to impose the prescription on the cornea, and determining a sequence of laser-energy ablations to impose the ablation profile on the cornea. The prescription provides a high-order optical correction. The ablation profile includes a first-segment profile and a second-segment profile. The second-segment profile corresponds to at least one high-order optical correction. The ablation sequence includes applying ablations corresponding to the first-segment profile prior to applying ablations corresponding to the second-segment profile.
    Type: Grant
    Filed: June 12, 2013
    Date of Patent: May 24, 2016
    Assignee: AMO Development, LLC
    Inventor: Julian D. Stevens