Abstract: A spectral measurement device includes: an optical band-pass filter section that has first to n-th wavelengths (n is an integer of 2 or more) having a predetermined wavelength width as a spectral band thereof; a correction operation section that corrects a reception signal based on an output optical signal from the optical band-pass filter section; and a signal processing section that executes predetermined signal processing based on the reception signal corrected by the correction operation section that corrects the reception signal based on the change in the spectral distribution of the reception signal.

Abstract: A single-shot spectral imager or imaging system which acquires multiplexed spatial and spectral data in a single snapshot with high optical collection efficiency and with the speed limited only by the readout time of the detector circuitry. The imager uses dispersive optics together with spatial light modulators to encode a mathematical transform onto the acquired spatial-spectral data. A multitude of encoded images is recorded simultaneously on a focal plane array and subsequently decoded to produce a spectral/spatial hypercube.

Abstract: A device for measuring a spectrum of a light beam, in a wavelength range chosen beforehand, the spectrum being generated by a sample to be analyzed, the optical measuring device including at least one light source, a measurement cell and a measurement detector placed on a measurement optical pathway, the measurement optical pathway being taken by a measurement optical beam emitted by the light source, and encountering the measurement cell, a self-calibration unit allowing any drift of the light sources, due to environmental conditions or conditions of use, to be taken into account independently of whether a sample to be analyzed is present in or absent from the measurement cell, the self-calibration unit including elements for creating a reference optical pathway, taken by a reference optical beam emitted by the light source, and not encountering the measurement cell, and a reference detector.

Abstract: A disclosed optical testing apparatus comprises: a plurality of optical fibers, each optical fiber having a collection end in optical communication with an output end; and a support member supporting the collection ends of the optical fibers so as to simultaneously view an examination region from different angles. A disclosed optical testing apparatus comprises a plurality of optical fibers having collection ends arranged to simultaneously view an examination region from a plurality of different angles. A disclosed optical testing apparatus comprises a plurality of optical fibers, each optical fiber having a collection end, the collection ends of the optical fibers arranged in fixed spatial relationship respective to one another to simultaneously view an examination region from different angles.

Abstract: The present invention relates to alkylglycoside-containing compositions and methods for increasing the stability, reducing the aggregation and immunogenicity, increasing the biological activity, and reducing or preventing fibrillar formation of a peptide, polypeptide, or variant thereof, for example insulin and Peptide T or analog thereof.

Abstract: A light source for an atomizing device, specifically an atom absorption spectrometer comprising one, two, or more lamps, whose ray can be selected by means of at least one two-dimensionally moveable optical selection element, and which can be directed in the direction of atomizing device. Fine-tuning is thereby achieved quickly with little constructive expenditure and with low costs. A very high degree of accuracy is possible from the selector through a rotational and highly adjustable rotation spindle.

Abstract: A light processor (such as a spectrometer) providing wavelength equalization for a sample pathway and a reference pathway by actuation of a light amplitude modulator. A chemometric processor including a light amplitude modulator capable of performing chemical analysis by applying weights to wavelengths of light, thereby reducing the need for electronic post processing.

Abstract: The present invention provides an improved system for identifying defects in a composite structure by providing a light source such that defects, and in particular dark defects on a dark background and/or light defects on a light background, can be identified by capturing images of the illuminated composite structure. In particular, the improved system for identifying defects in a composite structure may provide a reflective surface, dispersion elements, and multiple and/or moveable light source(s) and/or camera(s) in order to ensure that the most accurate images of any area of the composite structure, even curved or contoured areas, are captured and processed. As a result, the system of the present invention permits the operator to quickly identify and correct defects which would otherwise create structural flaws or inconsistencies that may affect the integrity of the composite structure.

Abstract: An inexpensive broadband source such as an ASE source, used for erbium amplifier measurements, compares well with the use of a prior art ITU grid. Deltas are less than 0.4 and 0.3 dB for gain and noise figure respectively. The spectral loading used to test erbium amplifiers needs to closely resemble conditions seen in the field. Use of an ITU grid is a good way of achieving this, however it is a costly solution and may restrict the spectral resolution. Use of a high power amplified spontaneous emission source gives a cost-effective alternative, which compares well with ITU grid measurements. In addition the spectral resolution of the measurement is then only limited by the spectral resolution of the optical spectrum analyzer.

Abstract: Systems and methods for analyzing a sample are disclosed. The system may include a light source operable to transmit light onto the sample, a detector operable to detect intensity of the light emitted from the sample, and a power modulator. The power modulator modulates the light source power such that light is emitted from the light source in more than one mode to reduce changes in the emitted light due to temperature changes in the light source.

Abstract: A device for the adjustable coupling of wavelengths or wavelength regions into the illumination beam path of a microscope, preferably in the beam path of a confocal microscope, comprising at least one dispersive element for wavelength separation of the illumination light and at least one at least partially reflecting element arranged in the wavelength-separated portion of the illumination light for reflecting back a wavelength region in the direction of the microscope illumination, and a device for the adjustable detection of object light coming from an illuminated object, preferably in a microscope beam path, comprising at least one dispersive element for wavelength separation of the object light and means arranged in the wavelength-separated portion of the object light for the adjustable stopping down or cutting out of at least one wavelength region and deflection in the direction of at least one detector.

Abstract: Fluorescence imaging of tissue is used as a diagnostic tool in which geometric effects and specular reflections are compensated for by normalizing a fluorescence image with a cross-polarized image.

Abstract: A device and process for measuring and analyzing spectral radiation within a desired wavelength range. A number of radiation sources are provided, in combination with a sensor for detecting radiation within the desired wavelength range. The radiation sources are selected to have spectral characteristics that are linearly independent from one another, but overlap so that, in combination, the radiation sources generate radiation over the entire desired wavelength range. Alternatively, a single radiation source generating radiation over the entire desired wavelength range is provided in combination with a plurality of sensors that have spectral sensing characteristics that are linearly independent from one another, but overlap so that, in combination, the sensors sense radiation over the entire desired wavelength range.

Abstract: Self-normalization of laser spectrometers is provided by I"/I laser modulation and detection. A single tunable diode laser is frequency modulated by a high S/N ratio triangle wave, mechanically chopped, passed through an isothermal in-line gas and reference chamber absorption cell, and synchronously detected to provide the I" and I signals. The preferred embodiment discloses isotopic ratio measurements. The invention has application to quantitative trace gas measurements generally.

Abstract: A dispersion transformer for limiting the data rate of an optical fiber transmission system. A transmission optical fiber, which connects a transmitter and a receiver, may have a bandwidth much greater than that necessary to transmit a desired predetermined maximum data rate. The transmitted signal is connected to wavelength disperser means which spatially separates the different wavelength components of the transmitted signal. Each wavelength component is then propagated with a different delay by optical fiber delay means. The wavelength component which propagates with the least delay through the transmission optical fiber is subjected to the least induced delay in the optical fiber delay means and that which propagates with the greatest delay through the transmission optical fiber is subjected to the greatest induced delay in optical fiber delay means, the remaining components being subjected to intermediate delays. The delayed wavelength components are combined to form a series of broadened optical pulses.

Abstract: In a spectrophotometer for measuring transmission spectra, the holder with a test sample is disposed inside the double monochromator between the intermediate slit and the second dispersive element and is capable of moving across the propagation path of the light flux at the output of the intermediate slit for placing the test sample in the path of the light flux and removing the sample from the path of the light flux.

Abstract: A dual beam differential spectrophotometer using a rotating chopper wheel having reflective transparent, and opaque sectors transmits light alternately through standard and sample material cells for comparison. Diffuse reflectors insertable in the material cells permit the apparatus to be used either as a differential spectrofluorometer or as a differential absorption meter.

Abstract: A fluorescence spectrophotometer in which the optical system for the excitation monochromator includes an arrangement for forming an image of the exit slit of the monochromator adjacent a first surface of the sample being evaluated and for forming an aperture image adjacent a second surface of the sample. Fluorescence from the sample is directed to an emission monochromator which likewise has an arrangement for forming an image of the emission monochromator's entrance slit adjacent a third surface of the sample and for forming an aperture image adjacent a fourth surface. The optical components are arranged such that the images of the slits lie in a single plane defined by the axial rays of the excitation and fluorescence beams, and in several advantageous arrangements the slit images are oriented at 90.degree. from the slits themselves. The intensity of the output signal may be further increased by locating mirrors behind the sample holder to direct the light back through the sample for a second pass.