Having Particles Suspended In Liquid Patents (Class 356/441)
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Patent number: 8139224Abstract: A particulate concentration detector including a detection mechanism having a light emission unit and light reception unit. The particulate concentration detector detects the concentration of particulates suspended in a liquid from the light amount detected by the detection mechanism. The detection mechanism includes a first light guide, a second light guide, a liquid chamber, and a third light guide. The first light guide is arranged at a location facing toward a light emission surface of the light emission unit. The second light guide is arranged at a location facing toward a light reception surface of the light reception unit. The liquid chamber is formed between the first light guide and second light guide and allows the liquid to flow therein. The third light guide is arranged in an oscillatable manner in the liquid chamber so as to face toward the first light guide and the second light guide.Type: GrantFiled: July 15, 2008Date of Patent: March 20, 2012Assignees: Toyota Jidosha Kabushiki Kaisha, Nippon Soken, Inc.Inventors: Noriyasu Amano, Rie Osaki, Kazuki Matsuo, Naoya Kato, Hitoshi Uda
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Patent number: 8098376Abstract: A novel low-power and compact laser spectroscopic sensor is described herein. Embodiments of the disclosed sensor utilize state-of-the-art microprocessors and digital processing techniques to reduce power consumption and integrate functions into a small device. In particular, novel software methods are disclosed which allow the use of low-power microprocessors which draw no more than about 0.02 W of power. Such low-power enables long battery life and allows embodiments of the sensor to be used in portable applications. In addition, the system architecture and methods described in this disclosure allow a single integrated embedded processor to control all the subsystems necessary for a laser spectroscopic sensor further reducing sensor size and power consumption. In addition, a power efficient method of calibrating a photoacoustic laser spectroscopic sensor is disclosed.Type: GrantFiled: October 6, 2006Date of Patent: January 17, 2012Assignee: William Marsh Rice UniversityInventors: Stephen So, Gerard Wysocki, J. Patrick Frantz, Frank K. Tittel
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Publication number: 20120002206Abstract: An optical-type turbidity sensor including a casing accommodating photo emitting means and photo receiving means therein, wherein the photo emitting means and the photo receiving means are arranged side-by-side on a same side of the casing, preferably underneath a same lens-shaped, transparent portion of the same, and are facing to, and spaced from, a reflecting surface carried by the casing and adapted to receive a light radiation from the photo emitting means for reflecting it towards the photo receiving means; the reflecting surface is operatively associated with means for varying a distance existing between the reflecting surface and the side of the casing provided with the photo emitting and photo receiving means arranged side-by-side.Type: ApplicationFiled: March 5, 2010Publication date: January 5, 2012Applicant: ILLINOIS TOOL WORKS INC.Inventors: Sergio Giordano, Domenico Pietrafesa
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Patent number: 8064063Abstract: A device (100) for assisting in optical characterisation of a sample fluid. The device can comprise a substrate (102) with at least one measurement reservoir (104) adapted for filling with the fluid (106) in a filling direction. The device (100) thereby is adapted for receiving an illumination beam (108) for illuminating the fluid (106) in the at least one measurement reservoir (104). The at least one measurement reservoir is adapted for varying the rate of change of an optical path length of the illumination beam in the fluid. The measurement reservoir properties are adapted for providing information of an optical path length of the illumination beam in the fluid at a plurality of moments during the filling with the fluid. Furthermore a corresponding optical characterisation device is described. The invention also relates to a corresponding method.Type: GrantFiled: July 20, 2007Date of Patent: November 22, 2011Assignee: Trinean NVInventors: Kris Naessens, Ronny Bockstaele, Bert Luyssaert, Roeland Baets
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Patent number: 8045166Abstract: A method of particle detection includes a shock wave generating step of irradiating a dispersion liquid having dispersed first particles having a first diameter and second particles having a second diameter larger than the first diameter, with a pulse laser, and generating a shock wave in the dispersion liquid, a migration speed difference imparting step of migrating and accelerating the first particles at a first acceleration speed, and the second particles at a second acceleration speed higher than the first acceleration speed, by the shock wave generated at the shock wave generating step, and a detecting step of detecting the first or second particles.Type: GrantFiled: May 2, 2007Date of Patent: October 25, 2011Assignee: National University Corporation Kyoto Institute Of TechnologyInventors: Nobuyuki Ichinose, Yoshiyuki Nonoguchi, Toshihiro Nakayama
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Patent number: 7981682Abstract: High resolution particle differentiation process and separation system that provides enhanced resolution of particles based upon selected particle characteristics. In particular, the system may include an enhanced resolution flow cytometer. In an embodiment, the invention can include at least one fluid source conduit (24) that introduces 0 fluid source stream (24) into an enhanced resolution nozzle (25) at an angle that enhances particle resolution by the cell sensing system (13).Type: GrantFiled: November 19, 2010Date of Patent: July 19, 2011Assignee: XY, LLCInventor: Kenneth M. Evans
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Patent number: 7964142Abstract: A sample analyzer includes a loading section in which a measuring unit is removably set, the measuring unit being adapted to receive a sample; and a control section which analyzes a signal acquired from the sample received in the measuring unit set in the loading section to provide a result of analysis of the sample; wherein the control section judges whether or not the measuring unit is properly set in the loading section.Type: GrantFiled: June 24, 2004Date of Patent: June 21, 2011Assignee: Sysmex CorporationInventors: Kazunori Mototsu, Seido Biwa
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Patent number: 7957002Abstract: An optical measurement apparatus can be provided, in which the sample is optically measured without loss of the illuminating light with high sensitivity. A glass plate as the transparent member 50 is placed in the interface between the end face 43 of the optical waveguide 40 guiding the illuminating light L generated by the laser light source 20 and the wall face of the capillary 30. According to the above feature, the air layer is prevented from existing in the interface between the end face 43 of the optical fiber 40 and the wall face of the capillary 30, thus the sample S can be optically measured with high sensitivity and few variability without causing the loss of the illuminating light L.Type: GrantFiled: March 13, 2009Date of Patent: June 7, 2011Assignee: The Furukawa Electric Co., Ltd.Inventors: Ken Tsukii, Jie Xu, Kenichi Kimura
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Patent number: 7933018Abstract: The present invention contemplates implementation of transitory downhole video imaging and/or spectral imaging for the characterization of formation fluid samples in situ, as well as during flow through production tubing, including subsea flow lines, for permanent and/or long term installations. The present invention contemplates various methods and apparatus that facilitate one-time or ongoing downhole fluid characterization by video analysis in real time. The methods and systems may be particularly well suited to permanent and periodic intervention-based operations.Type: GrantFiled: August 15, 2005Date of Patent: April 26, 2011Assignee: Schlumberger Technology CorporationInventors: Stephane Vannuffelen, Ahmed Hammami, Toru Terabayashi, Tsutomu Yamate, Terry Sopkow, John Ratulowski, John A. Kerr, Francois Auzerais, Robert J. Schroeder, Jeffrey A. Tarvin, Andrew L. Kurkjian, Laurent Prouvost
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Patent number: 7916294Abstract: A system for determining a solubility of a substance comprises a holder to hold a sample comprising an amount of the substance and an amount of the solvent system. The system further comprises a temperature conditioner to alter a temperature of the sample, an optical measurement device to measure an optical parameter of the sample and a control device to control at least the temperature conditioner and the optical measurement device. The control device may be programmed to alter the temperature of the sample by the temperature conditioner, measure the optical parameter of the sample by the optical measurement device, and determine the solubility of the substance from a change of the optical parameter of the sample as a function of the temperature.Type: GrantFiled: September 21, 2006Date of Patent: March 29, 2011Assignee: Avantium International B.V.Inventors: Emilio René Bodenstaff, Danny Dirk Pieter Willem Stam, Benjamin McKay, Mimoun Lamkadmi
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Publication number: 20110043807Abstract: A method for turbidity measurement in a measured medium uses a turbidity sensor, which comprises at least a first and a second emitter and at least a first and a second detector. The first and the second emitters are excited one after the other to produce light signals directed into the measured medium; wherein each light signal travels along a first propagation path through the measured medium to the first detector, and is converted by such into a first detector signal; and travels along a second propagation path through the measured medium to the second detector, and is converted by such into a second detector signal. A turbidity value is ascertained based on the first and the second detector signals; wherein, by means of at least one additional detector, to which at least one of the light signals travels along an additional propagation path, an additional detector signal is ascertained, and, on the basis of the additional detector signal, the turbidity value is checked as regards its plausibility.Type: ApplicationFiled: April 9, 2009Publication date: February 24, 2011Applicant: Endress + Hauser Conducta Gesellschaft fur Mess- und Regeltechnik mbH + Co. KGInventors: Edin Andelic, Rudiger Frank
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Patent number: 7889420Abstract: A color-tunable, reflective, paper-like display utilizes the unique optical properties of nano-engineered metal and metal-dielectric composite structures that exhibit a plasmon resonance. By changing the dielectric properties of a medium in which these structures are embedded, or by changing the spatial relationship of these structures, their optical absorbance and scattering spectra can be tuned. This enables simpler pixel architectures with better performance than is possible with fixed-color technologies. Low power video rate operation can be achieved in a paper-like display.Type: GrantFiled: September 10, 2009Date of Patent: February 15, 2011Assignee: Hewlett-Packard Development Company, L.P.Inventor: Gary A. Gibson
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Patent number: 7855078Abstract: High resolution particle differentiation process and separation system that provides enhanced resolution of particles based upon selected particle characteristics. In particular, the system may include an enhanced resolution flow cytometer. In an embodiment, the invention can include at least one fluid source conduit (24) that introduces 0 fluid source stream (24) into an enhanced resolution nozzle (25) at an angle that enhances particle resolution by the cell sensing system (13).Type: GrantFiled: August 15, 2003Date of Patent: December 21, 2010Assignee: XY, LLCInventor: Kenneth M. Evans
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Patent number: 7800757Abstract: The present invention is directed to a fast, nondestructive measurement method for determining the contents of solid, liquid and/or suspended flowing organic compounds. The arrangement according to the invention comprises a sample vessel, a pump, and a measurement cell which form a unit together with a spectroscopic measurement head. The measurement cell is connected to the pump, which can be regulated to vary the flow rate, and to the sample vessel by a pipe, and the spectroscopic measurement head and the regulatable pump have electrical connections to a controlling and evaluating unit. Due to its compact construction, the solution which makes use of the principle of transflection is also particularly suited to mobile use, for example, to determine the components of liquid manure while the latter is being dispensed. In principle, the solution can be transferred to any applications with suspensions or pumpable, homogeneous and inhomogeneous materials.Type: GrantFiled: February 22, 2005Date of Patent: September 21, 2010Assignees: Carl Zeiss Jena GmbH, Christian-Albrechts-Universitaet Zu KielInventors: Michael Rode, Helga Andree, Diane F. Malley
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Patent number: 7796262Abstract: The current invention provides methods for detecting trace analytes in solution or suspension using coupled micro-ring resonators. The methods of the current invention determine the presence and concentration of the target analytes in real time by exposing the micro-ring resonator to the analyte and determining the resulting rate of change of resonance wavelength experienced by a sensing micro-ring resonator as compared to a reference micro-ring resonator.Type: GrantFiled: May 31, 2007Date of Patent: September 14, 2010Assignee: Nomadics, Inc.Inventors: Shaopeng Wang, Akhilesh Ramachandran, Edward T Knobbe, Frederick Gorr Johnson, Brent Everett Little, David Wesley Goad
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Publication number: 20100208263Abstract: A method for detecting a presence of a particle in a fluid is disclosed. The method includes the steps of directing a beam of electromagnetic radiation into the transient fluid; providing a sensor to detect an intensity of the radiation after passing through at least a portion of the fluid; generating a data representing the intensity detected by the sensor; and analyzing the data based upon a statistical analysis to detect the presence of a particle in the fluid and determine whether the particle is water or a solid particle.Type: ApplicationFiled: January 29, 2010Publication date: August 19, 2010Inventors: Jed Stevens, Gregory Sprenger
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Patent number: 7771659Abstract: The invention relates to an arrangement and a method for the analysis of body fluids (21), whereby an image recording device (30) is arranged in a low-reflection, preferably zero-reflection chamber (16), provided with an illumination device (45) and connected to an electronic image analyzer. The image recording device (30) is focused on a container (20), containing the body fluid (21) in an analysis position (22), in order to take at least one image of the body fluid (21), analyzed by means of an image analysis software which determines the quality of the body fluid (21).Type: GrantFiled: January 11, 2003Date of Patent: August 10, 2010Assignee: PVT Probenverteiltechnik GmbHInventor: Michael Ziegler
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Publication number: 20100195105Abstract: The present subject matter relates to methods of high-speed analysis of product samples. Light is directed to a portion of a product under analysis and reflected from or transmitted through the product toward an optical detector. Signals for the detector are compared with reference signals based on a portion of the illuminating light passing through a reference element to determine characteristics of the product under analysis. Temperature within the analysis system is monitored and the output signals of the optical detectors are compensated or corrections are made within the analysis calculations to compensate or correct for the system temperature. The products under analysis may be stationary, moved by an inspection point by conveyor or other means, or may be contained within a container, the container including a window portion through which the product illuminating light may pass.Type: ApplicationFiled: March 27, 2008Publication date: August 5, 2010Applicant: UNIVERSITY OF SOUTH CAROLINAInventors: Michael L. Myrick, Robert P. Freese, William Soltmann, David L. Perkins, Leonard Zheleznyak
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Patent number: 7755759Abstract: Methods and systems for evaluating pigment dispersions with desired characteristics. More specifically, methods and systems for evaluating particle size of colorless or light color dispersions using a novel parameter described as particle size related scattering index (PSRSI).Type: GrantFiled: March 20, 2007Date of Patent: July 13, 2010Assignee: Xerox CorporationInventors: Lanhui Zhang, Lin Ma, Keith Wong, Francisco Lopez, Robert Altavela
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Patent number: 7745167Abstract: A method for monitoring fluid media, such as a dynamic biological system, in a biological reactor containing developing culture fluid media. The method includes the step of directing light into the fluid media by way of one or more optical fibers to produce an illuminated fluid media and then measuring the intensity of light reflected from the illuminated fluid media by way of one or more optical fibers, the optical fibers being partitioned from the fluid media by a transparent window having inner and outer surfaces; the fibers having ends terminating adjacent to and confronting the inner surface of the window and extending in a direction away from the window, the corresponding ends of the fibers being radially and circumferentially spaced from one another, the corresponding ends of the fibers having converging and intersecting longitudinal projections therefrom, the intersecting longitudinal projections from the fibers being entirely within the window. Additionally, a fiber-optic probe is discussed.Type: GrantFiled: September 28, 2006Date of Patent: June 29, 2010Assignee: Dow Global Technologies, Inc.Inventors: Richard S. Harner, Timm R. Richardson, Keith L. Haney, Torben R. Bruck, Lawrence C. Chew
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Patent number: 7742170Abstract: Described herein is a method and system for providing a countermeasure against laser detection systems using nanocomponent material that is tailored to cloak or obscure a target from detection by transmitted laser radiation. The nanodot material absorbs and/or down-converts the transmitted laser radiation. Similarly, described herein is a method and system for providing a countermeasure against laser systems intended to blind a target through the use of a specifically engineered nanocomponent material for absorbing and/or down-converting the radiation from the laser system.Type: GrantFiled: August 8, 2005Date of Patent: June 22, 2010Assignee: Science Applications International CorporationInventors: Scott Earl McNeil, Martin Joseph Fritts, Roy Reed Heddleston, Martin B. Mark
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Publication number: 20100149532Abstract: In the case of generating a diffraction grating resulting from the density distribution of particles by applying a spatially periodic electric field to a sample having particles dispersed movably in a medium, measuring diffracted light obtained by exposing the diffraction grating to a parallel light flux, and calculating the diffusion coefficient and/or size of the particles from the temporal change in the intensity of the diffracted light, the diffraction grating is exposed to multiple types of parallel light fluxes having mutually different wavelengths simultaneously or sequentially, the diffracted light is measured separately for each wavelength, and the measurement results are used selectively for calculation of the diffusion coefficient and/or size of the particles, and whereby the measurement can be carried out accurately without being affected by a plasmon resonance phenomenon even for metal particles.Type: ApplicationFiled: May 18, 2007Publication date: June 17, 2010Inventor: Naoji Moriya
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Publication number: 20100134798Abstract: The invention relates to a sensor for determining a concentration of a substance contained in a fluid-containing matrix, with a measurement chamber (5), a sender (3) for the emission of optical radiation (6) into the measurement chamber, and a receiver (4) for receiving optical radiation which has traversed the measurement chamber, wherein the measurement chamber is designed for bringing into the matrix and is filled with a specific fluid, and the wall (12, 13) is at least sectionally permeable to the diffusion of the substance. A control and evaluation circuit (7) is connected to the sender (3) and controls the sender (3), and is connected to the receiver (4) for selecting the receiver signals and determines, from the receiver signal, a measurement for the concentration of the substance in the matrix.Type: ApplicationFiled: June 7, 2008Publication date: June 3, 2010Inventors: Kai-Uwe Zirk, Hans-Joachim Freitag`
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Patent number: 7724371Abstract: An optical device for examining a fluid including a measuring space including a compulsory passage for the fluid to be examined, at least one source delivering a selected light to an optical illuminator serving to collect at least part of the light having traversed the compulsory passage and to deliver the selected light to analyze the collected light so as to deliver signals representing data borne by the collected light. The optical illuminator includes a first light guide including one end, opposite the source, and configured to deliver the light, derived from the source, in accordance with a selected geometry to illuminate the compulsory passage in a substantially uniform manner and under a substantially constant intensity.Type: GrantFiled: November 7, 2005Date of Patent: May 25, 2010Assignee: Horiba ABX SASInventors: Philippe Nerin, Paul Moreno, Didier Cremien
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Publication number: 20100072371Abstract: Apparatus derives a sample liquid property and has a container with an outlet section having an overflow edge at a horizontal sample surface. A light source above the surface generates a probe light beam at a non-zero angle ?1 to a normal to the surface. A detector above the surface detects intensity of light emitted out through the surface along a first detection axis forming a non-zero angle ?1 with the surface. An optical barrier between the probe light beam and the first detection axis blocks reflected or scattered light. An inlet section receives sample liquid and has an opening to the main section beneath the sample surface. A separating member separates the sample surface of the inlet section from the sample surface of the main section.Type: ApplicationFiled: December 1, 2009Publication date: March 25, 2010Applicant: SWAN Analytische Instrument AGInventor: HEINZ WAGNER
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Patent number: 7679743Abstract: The present invention relates to an apparatus and method for measuring the size of nanoparticles present in an aqueous solution as an infinitesimal quantity, and, more particularly, to a scheme that remotely measures the laser-induced breakdown of a fine nanoparticle using a probe beam in a non-contact manner, performs curve fitting on the symmetrical frequency distribution curve of the measured magnitude of a probe beam signal to form the shape of a Gaussian function, obtains calibration curves for the size of the nanoparticle from the peak and full-width at half-maximum thereof, and determines the size of an unknown nanoparticle from the calibration curves.Type: GrantFiled: December 29, 2008Date of Patent: March 16, 2010Assignee: Korea Atomic Energy Research InstituteInventors: Euo Chang Jung, Hye-Ryun Cho, Kyoung Kyun Park, Jei-Won Yeon, Kyuseok Song
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Publication number: 20100053622Abstract: A system and method for quantifying opaque inhomogeneities within a fluid sample. The system uses an optical lens system to focus a light beam onto a stage where the sample is introduced. The light beam is directed onto the sample in a pattern such that the intensity of transmitted light is measured as a function of path length. A photo detector measures the transmitted light through the sample. Fluctuations in transmitted light intensity are then correlated with detection of opaque inclusions in the sample. The system also includes an automated program which utilizes these optical concentration measurements to determine the fouling potential of visbroken tars, and regulates the introduction of chemical inhibitors into a visbreaker unit to improve the yield of light streams and/or economic value of product.Type: ApplicationFiled: November 10, 2009Publication date: March 4, 2010Applicant: GENERAL ELECTRIC COMPANYInventors: Andre Vanhove, Tiffany N. Morris, Alan E. Goliaszewski, Brian W. Lasiuk, Donato Vinciguerra
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Patent number: 7670846Abstract: The invention concerns a method for automatically differentiating between a sample liquid and a control liquid especially within the context of analytical measuring systems, wherein the presence of a special property of the control liquid and/or at least two criteria are used for the differentiation. In addition the invention concerns appropriate control liquids that are suitable for the new method.Type: GrantFiled: June 24, 2003Date of Patent: March 2, 2010Assignee: Roche Diagnostics Operations, Inc.Inventors: Guenter Frey, Carina Horn, Otto Gaa, Hans Kintzig, Hans-Ruediger Murawski
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Publication number: 20100021177Abstract: A method for imaging objects through turbid media includes generating a repetitive pulsed light beam under control of a pulse shaper, propagating the light beam through turbid media, and receiving and imaging the light beam at a sensor. Propagation through turbid media causes scattering of the light, and the sensor captures scattered pulses to produce an image. The pulse shaper controls pulse width, frequency, repetition rate and chirp of the generated light pulses according to a feedback signal received from the sensor, to improve image quality. A system for imaging objects through turbid media includes a laser for generating a light beam; a pulse shaper for controlling said light beam, and a sensor, in communication with the pulse shaper, for capturing the image of said light beam through a turbid medium. Pulse width is less than 250 femtoseconds to reduce attenuation of the light beam through the turbid medium.Type: ApplicationFiled: September 14, 2007Publication date: January 28, 2010Applicant: THE TRUSTEES OF DARTMOUTH COLLEGEInventor: Ulf Osterberg
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Publication number: 20090180121Abstract: A method of particle detection includes a shock wave generating step of irradiating a dispersion liquid having dispersed first particles having a first diameter and second particles having a second diameter larger than the first diameter, with a pulse laser, and generating a shock wave in the dispersion liquid, a migration speed difference imparting step of migrating and accelerating the first particles at a first acceleration speed, and the second particles at a second acceleration speed higher than the first acceleration speed, by the shock wave generated at the shock wave generating step, and a detecting step of detecting the first or second particles.Type: ApplicationFiled: May 2, 2007Publication date: July 16, 2009Applicant: National University Corporation KyotoInventors: Nobuyuki Ichinose, Yoshiyuki Nonoguchi, Toshihiro Nakayama
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Publication number: 20090168067Abstract: A front plane laminate useful in the manufacture of electro-optic displays comprises, in order, a light-transmissive electrically-conductive layer, a layer of an electro-optic medium in electrical contact with the electrically-conductive layer, an adhesive layer and a release sheet. This front plane laminate can be prepared as a continuous web, cut to size, the release sheet removed and the laminate laminated to a backplane to form a display. Methods for providing conductive vias through the electro-optic medium and for testing the front plane laminate are also described.Type: ApplicationFiled: March 10, 2009Publication date: July 2, 2009Applicant: E INK CORPORATIONInventors: Richard D. LeCain, Ara N. Knaian, Steven J. O'Neil, Gregg M. Duthaler, Guy M. Danner, Robert W. Zehner, Alberto Goenaga, Benjamin Max Davis, Randolph W. Chan, Jonathan D. Albert, Glen Crossley
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Patent number: 7544326Abstract: A flow cell and flow cytometer in which a nozzle at the end of a flow channel is disposed on a removable substrate held at a registered location on a flow cell. Other elements including illumination optics, light collection optics, and the flow cell may then be positioned at fixed locations and would not require subsequent periodic adjustment. The registered location for positioning the nozzle allows removal and replacement of the nozzle key with the nozzle subsequently positioned in the identical location.Type: GrantFiled: February 26, 2007Date of Patent: June 9, 2009Assignee: Becton, Dickinson and CompanyInventors: Pierce O. Norton, David R. Vrane, Shervin Javadi
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Patent number: 7511819Abstract: The present invention provides an apparatus and method for high resolution spectroscopy using a narrow light beam source such as a superluminescent diode (SLD) and a tunable optical filter (TOF) for analyzing a formation fluid sample downhole and at the surface to determine formation fluid parameters. The SLD and TOF have a matching etendue. The analysis comprises determination of gas oil ratio, API gravity and various other fluid parameters which can be estimated after developing correlations to a training set of samples using a neural network or a chemometric equation.Type: GrantFiled: July 14, 2006Date of Patent: March 31, 2009Assignee: Baker Hughes IncorporatedInventor: Rocco DiFoggio
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Patent number: 7508518Abstract: The present invention relates to a particle measuring method for irradiating light to a surface of a substrate to scatter the light so as to measure a condition of particles on the substrate based on the scattered light. The particle measuring method according to the present invention comprises the steps of: heating a certain liquid to obtain a steam; supplying the steam onto a substrate so that a content of the steam is absorbed by each particle, while a temperature of the substrate is maintained in such a manner that the steam does not condense on the substrate; cooling the substrate before the particle dries so that the content absorbed by the particle is solidified, while preventing generation of solidified substance on regions of the surface of the substrate to which no particle adheres; and irradiating light to the substrate to scatter the light and detecting the scattered light, under a condition in which the content absorbed by the particle has been solidified.Type: GrantFiled: March 27, 2008Date of Patent: March 24, 2009Assignee: Tokyo Electron LimitedInventors: Akitake Tamura, Kaoru Fujihara, Teruyuki Hayashi
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Publication number: 20080316486Abstract: A target substance-detecting apparatus comprises a target substance-detecting element comprising metal structures, a light irradiation section for irradiating the target substance-detecting element with a light, a light-polarizing section which polarizes the irradiating light and separates an output light emitted from the target substance-detecting element into a first polarized light and a second polarized light, first and second light-receiving sections for outputting first and second signals according to intensity of the first and second polarized lights, respectively; and a control section which determines peaks of absorbances of the first and second polarized lights by measuring the absorbances from the first and second signals respectively, and controls the target substance-detecting element so that the peak values of the first and second absorbances can be maximized and minimized respectively by controlling a incidence angle of formed by a vibration direction of the incident light and a main axis of thType: ApplicationFiled: June 20, 2008Publication date: December 25, 2008Applicant: CANON KABUSHIKI KAISHAInventors: Satoru Nishiuma, Norihiko Utsunomiya, Tetsunori Ojima
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Publication number: 20080273206Abstract: Disclosed are methods and systems that can be quickly and efficiently utilized to examine the kinetics of a growth and development protocol in a controlled environment, for instance in vivo. Disclosed systems can include a synthetic mineralization complex that can nucleate calcium phosphate mineral deposition in a controlled environment, for instance a controlled environment that can mimic a natural environment in which biomineralization takes place. Also disclosed are non-contact optical methods as may be utilized to examine the kinetics of a developing solid phase. Disclosed systems and methods can be beneficially utilized in high throughput screening in the development of drugs for the treatment and prevention of pathological calcifications such as osteoarthritis and atherosclerosis.Type: ApplicationFiled: April 23, 2008Publication date: November 6, 2008Applicant: University of South CarolinaInventors: Brian Genge, Licia Wu, Roy Wuthier
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Publication number: 20080252886Abstract: A system for determining a solubility of a substance comprises a holder to hold a sample comprising an amount of the substance and an amount of the solvent system. The system further comprises a temperature conditioner to alter a temperature of the sample, an optical measurement device to measure an optical parameter of the sample and a control device to control at least the temperature conditioner and the optical measurement device. The control device may be programmed to alter the temperature of the sample by the temperature conditioner, measure the optical parameter of the sample by the optical measurement device, and determine the solubility of the substance from a change of the optical parameter of the sample as a function of the temperature.Type: ApplicationFiled: September 21, 2006Publication date: October 16, 2008Applicant: AVANTIUM INTERNATIONAL B.V.Inventors: Emilio Rene Bodenstaff, Danny Dirk Pieter Willem, Benjamin McKay, Mimoun Lamkadmi
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Patent number: 7436515Abstract: This invention describes an improved method and apparatus for the analysis of fluid borne particles and which is especially suitable for the detection of airborne biological particles. In one aspect of the invention provides an apparatus for the detection of fluid borne particles which comprises a zone through which a fluid to be analyzed flows in use, a source of illumination to illuminate/irradiate fluid borne particles present in said zone, and a detector to detect light from the particles as an indicator of the presence or characteristics of the particles, wherein the apparatus comprises an integrating sphere and the zone is within the integrating sphere. The apparatus is highly sensitive and can be used for detecting airborne particles even where the particles are present at very low particle concentrations in the air.Type: GrantFiled: December 21, 2005Date of Patent: October 14, 2008Assignee: The Secretary of State of Defense, DSTLInventors: Paul Henry Kaye, Edwin Hirst
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Patent number: 7423751Abstract: The invention provides systems and methods for detecting aerosols. The systems and methods can be used to detect harmful aerosols, such as, bio-aerosols.Type: GrantFiled: February 8, 2006Date of Patent: September 9, 2008Assignee: Northrop Grumman CorporationInventors: Peter P. Hairston, Carl B. Freidhoff
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Patent number: 7400407Abstract: A meter for measuring the turbidity of a fluid includes a light source for directing a light beam through a fluid under test towards a reflective surface and a sensor for detecting light reflected from the reflective surface and passing back through the fluid under test. The meter outputs a signal indicative of the turbidity of the fluid under test.Type: GrantFiled: August 31, 2005Date of Patent: July 15, 2008Assignee: Avago Technologies ECBU IP Pte LtdInventors: Joh Joh Ng, Khee Boon Lim, Chee Wai Chia, Selvan Maniam
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Patent number: 7394545Abstract: A system and method for counting opaque particles within a fluid sample. The system uses an optical lens system to focus a light beam onto a sample on a multi-dimensional translation stage. The translation stage is moved in a pattern such that the intensity of the transmitted light is measured as a function of path length. A photo detector is used to measure the transmitted light through the sample. An analog-to-digital converter quantifies the transmitted light intensity. Changes in light intensity along the path length are correlated with the detection of an opaque particle. Data processing algorithms are implemented to automatically determine the background noise level associated with the acquired data and to set a discriminator level above which a particle is registered. The total number of particles and an areal density is reported along with an estimate of the uncertainty.Type: GrantFiled: July 11, 2005Date of Patent: July 1, 2008Assignee: GE Betz, Inc.Inventors: Andre Vanhove, Brian W. Lasiuk, Peter J. Codella, Wiley Lyle Parker
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Patent number: 7372063Abstract: The invention concerns a method for detecting gas bubbles in a liquid adapted to a device comprising a light source, a light detector and a data controlling and processing unit connected to a client system comprising the following steps: emitting light from the light source, acquiring successive measurements of the light intensity sensed by the light detector and calculating a variation between two successive measurements of said light intensity. In accordance with a first embodiment of the invention, the method further comprises a step which consists in comparing the variation between two successive measurements of light intensity to a threshold S. Advantageously, a warning counter is incremented by a value A when variation between two successive measurements is higher than the threshold S and decremented by a value B in the opposite case. A proportion of bubbles higher than a maximum authorized rate is detected when said warning counter exceeds a warning value C.Type: GrantFiled: November 25, 2003Date of Patent: May 13, 2008Assignee: SC2N Societe AnonymeInventor: Pascal Castro
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Patent number: 7365852Abstract: Methods and sub-systems for substantially optimizing the absorbance measurement in optical instruments are provided. A method comprises forming a liquid sample into a droplet extending between two opposing surfaces, passing a light beam through the sample, and varying the distance between the two opposing surfaces until a distance substantially corresponding to a optimum absorbance is obtained.Type: GrantFiled: November 24, 2004Date of Patent: April 29, 2008Assignee: Agilent Technologies, Inc.Inventor: Arthur Schleifer
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Patent number: 7362429Abstract: The present invention is directed to the use of a light absorbing wall material to eliminate stray light paths in light-guiding structures, such as those used for HPLC absorbance detection. More specifically, the present invention relates to the use of carbon-doped Teflon® AF, or “black Teflon® AF,” for all or part of the walls of a light-guiding flowcell adapted for use in HPLC absorbance detection.Type: GrantFiled: August 4, 2004Date of Patent: April 22, 2008Assignee: Waters Investments LimitedInventor: Anthony C. Gilby
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Patent number: 7342660Abstract: An apparatus comprises a detector, a pressure sensor and a processor. The detector is operable to detect light that is scattered by an aerosol that is associated with a pressure. The pressure sensor is operable to measure the pressure. The processor is coupled to the detector and to the pressure sensor, and is configured to receive at least a signal from the detector and the pressure sensor. The processor is further configured to use the received signals to calculate a volume of the first aerosol, and to output an output signal associated with the calculated volume. The various measurements can be repeated and compared, and the output signal can be a feedback signal for metering subsequent amounts of the aerosol, based on the comparison.Type: GrantFiled: September 30, 2003Date of Patent: March 11, 2008Assignee: DEKA Products Limited PartnershipInventors: David E. Altobelli, Larry B. Gray, Derek G. Kane
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Patent number: 7330262Abstract: The contents of a liquid medium are determined using a light source and an optical detector, for example a spectrometer. A longitudinally displaceable piston sucks the medium into a cylindrical glass measuring chamber and evacuates the liquid from the chamber. At least one measuring beam is directed through the medium, and at least one reference beam is directed outside the medium. The piston has cleaning/sealing rings mounted on its outer periphery which rub against an inner surface of the glass measuring chamber as the piston travels, to clean the surface.Type: GrantFiled: January 30, 2003Date of Patent: February 12, 2008Assignee: Endress+Hauser Conducta Gesellschaft fur Mess - und Regeltechnik mbH+Co. KGInventors: Friedrich W. Siepmann, Achim Gahr
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Patent number: 7201875Abstract: A flow cell and flow cytometer in which a nozzle at the end of a flow channel is disposed on a removable substrate held at a registered location on a flow cell. Other elements including illumination optics, light collection optics, and the flow cell may then be positioned at fixed locations and would not require subsequent periodic adjustment. The registered location for positioning the nozzle allows removal and replacement of the nozzle key with the nozzle subsequently positioned in the identical location.Type: GrantFiled: September 27, 2002Date of Patent: April 10, 2007Assignee: Becton Dickinson and CompanyInventors: Pierce O. Norton, David R. Vrane, Shervin Javadi
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Patent number: 7149396Abstract: An optical waveguide is constructed so as to comprise a non-solid core layer surrounded by a solid-state material. The non-solid core layer has an index of refraction which is lower than the index of refraction of the surrounding solid-state material, and light can be transmitted with low loss through the non-solid core layer. In an exemplary application, the non-solid core layer comprises a sample material whose light transmission, absorption, and/or interference characteristics are to be measured. In addition, a perpendicular waveguide portion may be included for use in injecting light into the core for measuring fluorescence characteristics associated with the sample material. Most preferably, the optical waveguide is generally structured as an anti-resonant reflecting optical waveguide (ARROW), which comprises a Fabry-Perot reflector adjacent to the core layer, whereby light is substantially prevented from leaking out of said core in a transverse direction.Type: GrantFiled: June 15, 2004Date of Patent: December 12, 2006Assignees: The Regents of the University of California, Brigham Young UniversityInventors: Holger Schmidt, Aaron Roe Hawkins
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Patent number: 7099012Abstract: Some embodiments of the invention provide an improved spectrometer that measures light emissions and/or reflection from a non-solid material that flows through a system of pipes. This spectrometer is designed to fit into a standard pipe system. The material flows past a distal end of the spectrometer that is inserted in the pipe system. The spectrometer has the ability to project light onto the material and collect a resulting light from the material through the distal end as the material flows past this end.Type: GrantFiled: October 15, 2003Date of Patent: August 29, 2006Assignee: Turner Designs, Inc.Inventors: James Crawford, David Doting, Robert Ellison, Sang Hoang, Steven Monsef, Frank J. Szczurko, Jr.
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Patent number: 7050166Abstract: The invention concerns a method for determining the particle size distribution (PSD) of bridging agents in fluids, particularly aqueous fluids used in hydrocarbon recovery such as drilling fluids, drill-in fluids, completion fluids, and the like. It was discovered that the PSD could be selectively determined for calcium carbonate as a bridging agent because it auto-fluoresces. The method is reproducible and is not bothered by the presence of other particles such as drill solids which interferes with conventional methods, for instance, light-scattering techniques. The light used to fluoresce the bridging agent may be filtered to a particular frequency if there are other components present that fluoresce. Flow cytometry is another technique that could be used to implement the invention.Type: GrantFiled: October 30, 2002Date of Patent: May 23, 2006Assignee: Baker Hughes IncorporatedInventors: Ronald G. Bland, Tom A. Jones