Abstract: A refrigeration subsystem removably received within a base machine to cool an object. The subsystem includes a body with an opening that receives the object. An evaporator thermally communicates with the object, which is cooled by refrigerant flowing through the evaporator. A compressor receives the refrigerant downstream of the evaporator and increases a refrigerant pressure. A condenser receives the refrigerant downstream of the compressor, which cools the refrigerant. An expansion device receives the refrigerant downstream of the condenser and decreases its pressure, the evaporator being downstream from the expansion device. A refrigerant circuit fluidly couples the evaporator, compressor, condenser, and expansion device such that the refrigerant flows therebetween, all of which are coupled to the body and move together therewith. The refrigerant circuit forms a closed loop that remains unbroken when the body of the refrigerant subsystem is removed from the base machine.

Abstract: A magnetic stirrer (11) comprises a magnetic drive and a placement surface (17) for a laboratory vessel containing a substance to be stirred. The magnetic drive is designed to generate a magnetic field which varies such that a magnetic stirring element can be driven to produce a stirring motion in the laboratory vessel, in order to stir the substance. The magnetic stirrer (11) also comprises a heating device (15), which is designed to heat the placement surface in order to heat up the substance, and a display device (23), which is designed to display the current temperature of the placement surface.

Abstract: A bioreactor system and packaging is provided. The bioreactor system includes a vessel for housing biomaterials for processing and a support structure. The vessel includes a flexible material defining a chamber and a mixing system positioned within the chamber. The mixing system includes an agitator for imparting motion and mixing to the contents of the vessel and includes a base affixed to the flexible material at a base section of the chamber, a shaft moveably mounted in the base and extending from the base into the chamber and at least one mixing element mounted to the shaft, the shaft configured to be driven by a motor magnetically coupled to the shaft and external to the lower portion of the chamber. The support structure is connected to the mixing system such that the shaft is moveable therein and configured to cooperate with an external structure to provide support for the shaft.

Abstract: Systems, methods, and devices are disclosed for automatically and programmably preparing food. Devices include a container that includes a cavity configured to store at least one food ingredient, where the cavity defines an internal volume of the container. The devices also include a first plate coupled to a first end of the container, where the first plate includes at least one hole configured to receive the at least one food ingredient. The devices further include a second plate coupled to a second end of the container, and a plurality of thermoelectric devices coupled to the container, where the plurality of thermoelectric devices is configured to exchange thermal energy with the container. The devices also include a first thermal conduit coupled to a first side of each of the plurality of thermoelectric devices, and a second thermal conduit coupled to a second side of each of the plurality of thermoelectric devices.

Abstract: Systems, methods, and devices are disclosed for preparing food. In some embodiments, a food preparation device may include a container that includes a cavity that may define an internal volume of the container. The food preparation device may also include a first plate coupled to a first end of the container. The first plate may include at least one hole configured to receive the at least one food ingredient. Also included may be a second plate coupled to a second end of the container and a mixing device coupled to the first plate. The mixing device may be configured to mix at least a portion of the internal volume of the container. The food preparation device may also include a heat transfer device coupled to the container. The heat transfer device may be configured to exchange thermal energy with the internal volume of the container.

Abstract: Disclosed is a sample processing method for processing a target component in a sample by use of a sample processing chip having a storage portion and a droplet forming flow path, the sample processing method including: storing, in the storage portion, a mixture of the target component and a predetermined amount of a diluent for causing the target component to be encapsulated by one molecule or by one particle into a droplet; heating the mixture in the storage portion to cause thermal convection in the storage portion thereby to mix the target component and the diluent together; and in the droplet forming flow path, forming droplets in a dispersion medium, each droplet containing the diluted target component and a reagent that reacts with the target component.

Abstract: An electromechanical nixtamalization system consisting of a rotary reactor, which turns on a horizontal axis and has a single-piece inner steel container without internal blades. It has resistors, a ceramic fiber layer, and a detachable stainless steel plate, and is fed by the maize grains introduced into an upper receiving hopper, and a cooling vat with a lid; and an interior and intermediate surface, as well as a cooling chamber located between the interior and intermediate walls, coated in a high-pressure polyurethane lining.

Abstract: The present invention has an object to provide a vacuum electric cooker as can be easily worked by an operator and as can minimize a stress to be applied to the container. The vacuum electric cooker of this invention includes a cooker body having a horizontal base and a stand section, a cooker container including a cooking tool, a cover member having a discharge nozzle, a connecting arm having a base end attached to the stand section as to rock in a vertical plane between a horizontal active position and a vertical inactive position. A connecting nozzle is attached to the connecting arm and connected to the discharge nozzle when the connecting arm is at the active position. A vacuum pump is disposed in the cooker body, and a tube is connected to the vacuum pump and the connecting nozzle.

Abstract: A continuous flow dryer system according to various embodiments can include a source for supplying a material to be treated having a high moisture content, such as a distiller wet grain, a profile screw compression dryer, a profile screw, and a drive coupled to the profile screw for axially rotating the profile screw. The profile screw compression dryer includes an inlet for receiving the material for drying, which is fed therein in a controlled manner. The profile screw is provided within the housing of the dryer. The profile screw has a diameter that increases in dimension in a direction away from the inlet for increasing the compressive force applied to the material to assist with drying as the profile screw rotates and moves the material longitudinally along the profile screw to produce a final product, for example, a distiller dried grain for use as an animal feed.

Abstract: To suppress the thermal expansion of a slide bar and to prevent occurrence of failures such as galling or malfunctioning to the slide bar, a resin discharge mechanism, provided in mixing equipment that includes a barrel having a hollow interior and a pair of mixing rotors accommodated in the barrel and that mixes a resin material by causing the paired mixing rotors to rotate within the barrel, for discharging a part of the resin material mixed by the mixing rotors to an outside of the barrel, the resin discharge mechanism including: a resin discharge passage provided in the barrel, and communicating an inside of the barrel with the outside of the barrel; a slide bar closing or opening the resin discharge passage by moving across the resin discharge passage; and a cooling device provided within the slide bar, and cooling the slide bar using a cooling fluid.

Abstract: A wearing body or bushing having an axial twin borehole for receiving a twin screw for extruding meltable material, in particular plastic. In order to avoid cracking and to save material, the wearing body has a radial cross section with an outer contour, which is convexly curved over the entire circumference and is in the form of an oval, and with first and second axes of symmetry, which run perpendicularly to one another and define a point of intersection which lies on the extrusion axis. The width of the oval on the first axis of symmetry is greater than the height of the oval on the second axis of symmetry.

Abstract: The problem addressed by the present invention is providing a fluid processing method including extraction that can extract material to be extracted continuously with high efficiency. In a thin film fluid formed between at least two processing surfaces (1, 2) disposed facing each other so as to be able to approach to and separate from each other such that at least one rotates relative to the other, a fluid processing that extracts at least one kind of material to be extracted in at least one kind of the extraction solvent that can extract that material to be extracted is carried out.

Abstract: The continuous treatment device (10) includes a tank (11) of elongated shape and that determines a mixing chamber (15) which includes, at a first end, at least one inlet orifice (12) for the raw material and, at a second end, at least one outlet orifice (13) for the treated material, and also, between these orifices, at least one agitator shaft (16) equipped with blades (17) suitable for continuously mixing and advancing the material in the mixing chamber (15) from the inlet orifice to the outlet orifice. The device also includes a mixing screw (25) in the bottom of the tank, which is positioned in the mixing chamber (15), below and parallel to the at least one shaft (16), and which is suitable for being rotated, about at least one direction of rotation, the opposite way from the advance of the material from the inlet orifice to the outlet orifice.

Abstract: A refrigerator having a curd maker to make curd directly disposed in a refrigerating compartment wherein curd is made by the curd maker disposed in the refrigerating compartment and is kept fresh. The refrigerator includes a curd maker provided in a refrigerating compartment to ferment milk into curd, wherein the curd maker includes a case including an outer case forming an external appearance of the case and an inner case provided in the outer case, an insulation member provided between the outer case and the inner case, a curd container received in the inner case to store milk, a heater provided between the inner case and the insulation member to heat the curd container, a fan to supply cool air from the refrigerating compartment to the curd container to cool the curd container, and a temperature sensor to measure temperature in the curd maker.

Abstract: The present invention relates to a multifunctional milk bottle holder, and more particularly, to a multifunctional milk bottle holder which: is capable of providing information related to whether bottle-feeding is occurring using the inclination of the holder for feeding, wherein power is automatically turned on when a milk bottle containing liquid milk is placed in the holder for feeding; is capable of providing information related to the temperature of the liquid milk while maintaining the temperature of the liquid milk for a predetermined period of time; and has excellent price competitiveness due to reduced manufacturing costs. Also, the holder is capable of developing the senses of vision and hearing through the operation of a mobile which rotates in the holder and of a sound source generation unit, thereby ensuring ease of use.

Abstract: A refrigerator includes a refrigerator cabinet, an ice maker disposed within the refrigerator cabinet, a pump fluidly connected to the ice maker and configured for pumping cooling media to the ice maker, and a motor operatively connected to the ice maker and configured to provide oscillating movement to the ice maker. The pump is operatively connected to the motor such that driving of the motor results in the pumping of the cooling media with the pump.

Abstract: A hot-beverage-making apparatus, in particular for milk beverages such as cappuccino, chocolate and the like, comprising a container extending along an axis, a lid closing the container, a rotary mechanical stirrer fitted with an impeller, and a steam wand connectable to a steam source and having an end steam outlet. The stirrer and the wand extend, sloping with respect to each other, inside the container, and the end steam outlet of the wand is located above and radially eccentric with respect to the impeller of the stirrer.

Abstract: A fluid heating system includes a tank assembly having an interior surface bounding a chamber, the tank assembly having: a sidewall encircling the chamber and extending between a first end and an opposing second end, the first end bounding an opening to the chamber; and a lid movable between a first position wherein the opening to the chamber is exposed and a second position wherein the lid is disposed over the opening. A collapsible bag is removably disposed within the chamber of the tank assembly, the collapsible bag bounding a compartment adapted to hold a fluid. Systems are provided for controlling the temperature of fluid within the collapsible bag when the collapsible bag is positioned within chamber of the tank assembly. A mixing element is disposed within the compartment of the collapsible bag.

Abstract: A stirrer (1; 100) for stabilizing liquid binding unfinished products intended to form ceramic items comprising a support shaft (2) individuating a longitudinal rotation axis (Y) and contained into a mixing tank (V) of the liquid binding unfinished product, motorization means (3) operatively connected with the support shaft (2) in order to rotate it around the longitudinal axis (Y), and a main operating blade (4), coupled with the support shaft (2) through interconnection means (5) in such a way as to be contained into the mixing tank (V) in order to interfere with the liquid binding unfinished product and cause its continuous mechanical mixing action inside the mixing tank (V) itself when the support shaft (2) rotates around the longitudinal axis (Y).

Abstract: The present invention relates to an apparatus for mixing and controlling the temperature of laboratory vessel contents with an accommodating device in detachable connection with an exchangeable block for accommodating and controlling the temperature of laboratory vessels and with a drive by which the accommodating device can be set in a mixing motion, and with a temperature control device with a heat source or sink in heat-conducting connection with the exchangeable block at least through in each case at least one adjoining contact face firstly on the accommodating device and secondly on the exchangeable block, which is characterized in that the detachable connection is maintained by a spring element which, by virtue of its spring force, horizontally clamps together a first undercut between the accommodating device and the exchangeable block in at least one first direction.

Abstract: A system for dispersing finely dispersed solids into high-viscosity products includes, in a container, a coaxial stirring system having stirring elements on two independently drivable, coaxially arranged shafts. A positive-displacement, close-wall-clearance stirring element on the one shaft and a plurality of stirring elements on a central shaft are arranged in such a manner that, in an upper mixing region of the container, a combination of the positive-displacement, close-wall-clearance stirring element and stirring elements for forming an ideally mixed zone is provided, and in a mixing region downstream of the upper mixing region of the container, stirring elements for developing a plug-flow zone are provided. A positive-displacement pump is provided in a region downstream of the plug flow zone as a discharge zone.

Abstract: A soup maker includes a container mounted to an annular seat receiving a heat conducting pan that receives food to be cut by a cutter coupled with a transmission shaft driven by a motor. A heating pan abuts a bottom of the thermally conducting pan and is connected to a heating tube electrically connected to a power supply terminal. A temperature sensor abuts the heating pan. A base includes a coupling portion having a terminal hole and a sensor hole. A positioning plate presses against a positioning switch on the coupling portion when the annular seat couples with the coupling portion, with the power supply terminal and a coupling section of the temperature sensor respectively extending into the terminal hole and the sensor hole for electrical connection with the control circuit board, allowing the control circuit board to control the motor and the heating tube.

Abstract: A multiscrew extruder device for production of elastomeric compounds is intended for manufacturing tires for vehicle wheels. The device includes a holding body; a mandrel inserted in the holding body extending along a longitudinal axis and delimiting an annular chamber with the holding body; and a plurality of extrusion screws disposed in the annular chamber and parallel to the longitudinal axis. A first circuit for a heat-exchange fluid for temperature control is formed in the mandrel and includes a central channel extending in the mandrel along the longitudinal axis and a plurality of parallel peripheral channels extending in a peripheral portion of the mandrel close to the annular chamber and in fluid communication with the central channel.

Abstract: A method for inactivating a fluid culture includes inserting a collapsible bag within a chamber of a tank assembly. A fluid is dispensed into a compartment of the collapsible bag, the fluid including a culture containing live cells or microorganisms. A lid is positioned over an opening of the tank assembly so that the collapsible bag is substantially enclosed within the tank assembly. The fluid within the collapsible bag is heated to an inactivation temperature that is sufficiently high to kill all of the live cells or microorganisms within the fluid. In one embodiment, the fluid within the flexible bag is mixed while the fluid is being heated to the inactivation temperature.

Abstract: A method and apparatus for preparing a cellulosic feedstock are disclosed. Embodiments of the method comprise passing the cellulosic feedstock through an optional impregnation chamber to an outlet of the impregnation chamber, passing the cellulosic feedstock from the outlet of the impregnation chamber to a holding tank having an inlet and an outlet, and conveying the cellulosic feedstock downwardly and laterally as it travels through the holding tank. Embodiments of the apparatus comprise at least one sidewall defining a passage. The passage has an upper portion and a lower portion, and the lower portion has a greater cross-sectional area than the upper portion. At least one inlet is provided adjacent the upper portion, and at least one outlet is provided adjacent the lower portion, at an elevation below the inlet.

Abstract: A method and apparatus for preparing a cellulosic feedstock are disclosed. Embodiments of the method comprise obtaining a cellulosic feedstock having a moisture content of 30 wt % to 60 wt %; passing the cellulosic feedstock through a heated holding tank; withdrawing the cellulosic feedstock from the holding tank; and, subsequently subjecting the cellulosic feedstock to hydrolysis. Embodiments of the apparatus comprise at least one sidewall defining a volume having an upper portion and a lower portion. At least one inlet is provided adjacent the upper portion, and the inlet is in fluid communication with an impregnation chamber provided upstream from the holding tank. At least one outlet is provided adjacent the lower portion, and the outlet is in fluid communication with hydrolysis reactor positioned downstream from the holding tank. At least one conveyor is positioned adjacent the at least one outlet. A heating jacket provided on at least a portion of the apparatus.

Abstract: In an emulsifying arrangement comprising a tubular emulsifying chamber with two end areas for a spiral flow with a spiral flow direction, at least one inlet for conducting two non-mixable fluid fractions into the emulsifying chamber at the first end area and at least one outlet for conducting the fluid mixture out of the emulsification chamber at the second end area wherein the emulsifying chamber has between the two end areas a cross-section which is symmetrical around an axis of symmetry and is provided with at least one curved area disturbing the spiral flow through the tubular chamber.

Abstract: The invention relates to a cylindrical tank for the thermal treatment of a food product which includes heating and/or cooling means for the food product, in addition to a mixer housed so as to be revolving in its interior. The tank has a cylindrical mantle, closed by a rear bottom and by a front flange, there also being means for feeding the mentioned product inside the tank. At least one temperature sensor of the food product is also positioned in correspondence with an area situated in the front portion of the mantle, corresponding to the discharge area of the same food product from the tank. The invention also relates to machines which use the above-mentioned tank.

Abstract: A polymer processing system includes a mixer. The mixer includes at least one side wall and a bottom wall that cooperate to define a chamber. At least one side wall also defines a bore. The mixer also includes a pair of rotors that are disposed in the chamber and are rotatably received by the at least one side wall for mixing polymers. The mixer also includes at least one injector that at least partially extends through the bore of the at least one side wall. The polymer processing system also includes a ram that is movably connected to the mixer. The polymer processing system also includes a compressed air supply that is fluidly connected to the at least one injector to supply compressed air to the chamber through the at least one injector.

Abstract: Provided according to some embodiments of the invention are methods of manufacturing a pharmaceutical composition. In some embodiments, such methods include homogenizing at a first excipient composition that includes a viscosity agent and at least one solvent to form a first premix composition; separately homogenizing at least one active pharmaceutical ingredient (API) and a second excipient composition to form a second premix composition; and combining the first premix composition and the second premix composition to form the composition. The pre-mixing of constituents may increase the stability of the API and provide uniformity of the dispersion of the constituents throughout the final topical composition.

Abstract: The assembly includes a base and a mixing bowl. The base is adapted to receive the mixing bowl and has a receiving surface with a concave part. The mixing bowl has an outer surface with a convex part positively fitting into the concave part. In a connected position, the convex part and the concave part are adjacently connected. Also in the connected position, the mixing bowl is rotatable with regard to the base around at least one axis of all axes intersecting a center point. Further in the connected position, the base and the mixing bowl are releasably held together by magnetism, preferably via a magnetic interaction between the base and the mixing bowl.

Abstract: In this disclosure, a method is described wherein the method comprises mixing a therapeutic gas or a therapeutic liquid or a combination thereof and a liquid carrier in a high shear device to produce a dispersion; and administering the produced dispersion intravenously to a patient; wherein the produced dispersion contains nanobubbles of the therapeutic gas or droplets of the therapeutic liquid with a mean diameter of less than about 1.5 ?m. In this disclosure, a system is also described wherein the system comprises a therapeutic gas source or a therapeutic liquid source or a combination thereof; a liquid carrier source; a high shear device (HSD) having an inlet, an outlet, at least one rotor, and at least one stator separated by a shear gap; and a pump configured to control the flow rate and residence time of a fluid passing through the high shear device.

Abstract: In this disclosure, methods and systems for drug delivery utilizing high shear are disclosed. In an embodiment, a method comprises (1) subjecting a therapeutic fluid containing a drug to high shear; and (2) obtaining a processed therapeutic fluid, wherein the processed therapeutic fluid contains the drug in nano-size. In an embodiment, a method comprises (1) subjecting a drug carrier and a therapeutic fluid containing a drug to high shear; and (2) obtaining a processed therapeutic fluid, wherein the processed therapeutic fluid contains the drug carrier loaded with the drug. In an embodiment, a method comprises (1) applying high shear to a drug carrier and a therapeutic fluid containing a drug; (2) obtaining a processed therapeutic fluid, wherein the processed therapeutic fluid contains the drug-loaded carrier; and (3) modifying the drug-loaded carrier with a targeting moiety to obtain a modified drug-loaded carrier.

Abstract: The invention relates to a cylindrical tank for the thermal treatment of a food product, of the type including heating and/or cooling means of the food product, in addition to a mixer housed so as to be revolving in its interior. The tank has a cylindrical mantle, closed by a rear bottom and a front cover, there also being means (for feeding the product inside the tank. At least one temperature sensor of the food product is also situated in correspondence with this cover, with a sensitive part which, when the cover is closed, is in contact with the product contained in the tank.

Abstract: The present invention relates to an automated solution dispenser for dispensing a solution having a defined list of characteristics. In particular, the automated solution dispenser according to the present invention is provided with one or more of the following modules: Central Mixing Chamber (CMC), Flush and Verification System (FVS), Liquid Handling System (LHS), Control System (CS), Pivot Pipe System (PPS), Solid Handling System (SHS) (which includes a Delivery mechanism and a Measuring mechanism), a Bottle Handling System (BHS), a Water Purification System (WPS) and Bottle Marking/Label (BM). The combination of one or more of these modules enables the automation of the creation of solution having the required characteristics.

Abstract: A fluid heating system includes a tank assembly having an interior surface bounding a chamber, the tank assembly including a sidewall and a lid. A collapsible bag is removably disposed within the chamber of the tank assembly, the collapsible bag bounding a compartment adapted to hold a fluid. A boiler can be used for pumping heated fluid through the wall of the tank assembly for heating the fluid within the collapsible bag. An impeller is disposed within the compartment of the collapsible bag. An elongated drive shaft is removably coupled with the impeller such that rotation of the drive shaft facilitates rotation of the impeller within the compartment of the collapsible bag. A drive motor assembly is coupled with the drive shaft, the drive motor assembly being adapted to rotate the drive shaft when the lid is in an open or closed position.

Abstract: The invention relates to a device for controlling the temperature of laboratory vessels, comprising at least one vessel receptacle for receiving the laboratory vessels, at least one removably designed peripheral unit, and a base unit which has a temperature control device and a mounting for placing the at least one removable peripheral unit in a defined position, characterised in that the base unit and the at least one peripheral unit each have at least one coupling element, with said elements, when the peripheral unit is placed onto the base unit in the defined position, forming at least one releasable coupled pair by which the electrical power and/or at least one signal can be transmitted.

Abstract: The present invention relates to an apparatus for mixing and controlling the temperature of laboratory vessel contents with an accommodating device in detachable connection with an exchangeable block for accommodating and controlling the temperature of laboratory vessels and with a drive by which the accommodating device can be set in a mixing motion, and with a temperature control device with a heat source or sink in heat-conducting connection with the exchangeable block at least through in each case at least one adjoining contact face firstly on the accommodating device and secondly on the exchangeable block, which is characterized in that the detachable connection is maintained by a spring element which, by virtue of its spring force, horizontally clamps together a first undercut between the accommodating device and the exchangeable block in at least one first direction.

Abstract: A medical system and method can used to treat a bone. The system and method can include the preparation of bone cement to be used in the treatment. A non-liquid component and a liquid component can be combined to form a bone cement. A vacuum system can be used to saturate the non-liquid component with the liquid component. The bone cement and/or components can be heated and/or cooled.

Abstract: The invention relates to an emulsification device for continuously producing emulsions, nano-emulsions, and/or dispersions having a liquid crystalline structure, comprising a) at least one mixing system, b) at least one drive for the stirring element, and c) at least one delivery unit for each component or each component mixture.

Abstract: The application relates to a device for mixing and kneading masses (1), in particular chocolate masses, and to a method for mixing and kneading masses, in particular chocolate masses. The device comprises a kettle (2) having an inner wall (3), which at least partially emulates the outer surface of a rotational body, and a shaft (11) and at least one tool (10, 13) fastened thereto. At least one, in particular planar, deflector surface (8) is arranged in the kettle (2), the surface extending in the axial direction.

Abstract: Presented herein is a mixing apparatus to mix liquid and solids, solids and solids, liquids and liquids or combinations thereof into a homogenous solution in a sealed container shaken in a side to side, up and down, and/or orbital pattern with a warming plate to heat the contents to a desired temperature or for a specific time period with a decreased risk of foreign contaminants in accordance with prescribed instructions for preparing a mixture.

Abstract: The invention provides an electrically-driven kitchen machine including a food mixer or a food processor. The machine has a support platform for supporting a receptacle for foodstuffs to be mixed or otherwise processed. The machine has an electric motor used to drive mixing or processing tools disposed in the receptacle; and a heater for heating the foodstuffs in the receptacle. In order to ensure that the temperature of the foodstuffs is accurately determined, the base of the receptacle consists of multiple layers, including a first metallic material, such as aluminum, having a relatively high thermal conductivity, sandwiched between outer and inner skins of a second metallic material of lower thermal conductivity than the first metallic material. The machine is also provided with first and second probes, each protruding through the receptacle-supporting platform and urged upwardly to contact the inner skin and the first metallic material respectively.

Abstract: The present invention relates to a process for the preparation of a mixture for producing lithium titanium spinel Li4Ti5O12, having the step of mixing Li2CO3 and TiO2 in a vessel (1) in which at least one oblong element (2) with a first end (2a) and a second end (2b) is arranged such that the first end (2a) points towards an inner wall (1a) of the vessel (1) and is at a distance d from same, wherein the mixing step is carried out by allowing the vessel (1) to rotate and holding the oblong element (2) in its position, with the result that a relative movement takes place between the inner wall (1a) of the vessel (1) and the first end (2a) of the oblong element (2), wherein the distance d is kept constant during mixing. In addition, the invention relates to a process for the preparation of lithium titanium spinel Li4Ti5O12 from a thus-obtained mixture and its use as anode material in rechargeable lithium-ion batteries.

Abstract: The present invention relates to functionally closed systems for mixing and delivering microbubble pharmaceuticals. Described is a device comprising a rigid outer layer and a flexible bladder wherein mixing occurs using external mixing sources. Also included is a system for dispensing the pharmaceuticals to its end use after mixing. Methods for mixing and dispensing microbubble pharmaceuticals are also described.

Abstract: An apparatus for and method of enabling enhanced, selective agitation of liquid containing a solid-phase reagent. The apparatus includes at least one liquid-bearing container, a circular tray, and a motor. The liquid-bearing container(s) includes at least one internal baffle that imparts turbulent agitation to the liquid when flowing from one end of the container to an opposite end. The circular tray is adapted for selective rotation about a vertical axis of rotation. The rotary circular tray assembly includes container-receiving stations that selectively retain a respective liquid-bearing container in an inclined or pitched orientation with respect to a horizontal plane. The motor creates centrifugal force, which causes liquid in the container(s) to travel from the first end of the container to the second end of the container via the internal baffle(s), agitating the liquid and the solid-phase portions of the reagent.

Abstract: The invention relates to a device comprising a substantially cylindrical housing (2) in a mixing region (7). Said housing comprises at least one outlet channel (15) having an outlet opening (6) in the mixing region (7) and at least one rotationally supported mixing shaft (4) having at least one discharge element (3) having an effective surface. The discharge element (3) can be guided past the outlet opening (6) when used properly, wherein a projection of the effective surface (8) parallel to the outlet channel axis covers the smallest outlet channel cross section of the outlet opening (6) at least once per revolution of the discharge element (3) by at least 45%, preferably by at least 50%, particularly preferably by at least 55%, and most particularly preferably by at least 60%.

Abstract: A fluid heating system includes a tank assembly having an interior surface bounding a chamber, the tank assembly including a sidewall and a lid. A collapsible bag is removably disposed within the chamber of the tank assembly, the collapsible bag bounding a compartment adapted to hold a fluid. A boiler can be used for pumping heated fluid through the wall of the tank assembly for heating the fluid within the collapsible bag. An impeller is disposed within the compartment of the collapsible bag. An elongated drive shaft is removably coupled with the impeller such that rotation of the drive shaft facilitates rotation of the impeller within the compartment of the collapsible bag. A drive motor assembly is coupled with the drive shaft, the drive motor assembly being adapted to rotate the drive shaft when the lid is in an open or closed position.

Abstract: Disclosed is a mixing device for mixing, in particular, contents of laboratory vessels. The mixing device has a receiving device for receiving mixtures, a drive for setting the receiving device in a mixing movement relative to a chassis in which the receiving device moves on a closed path, and a bearing for guiding the receiving device in the mixing movement. The bearing has at least two supports, each with two bearing areas spaced apart from each other and having at least substantially no translatory and at least two rotational degrees of freedom. One bearing area bears the support at the chassis, and the other bearing area bears the receiving device at the support. The bearing has a guidance device, which guides the rotation of the receiving device relative to the chassis during the mixing movement.

Abstract: In an embodiment, an apparatus includes a disposable and flexible mixing tank, configurable as a bag, having a sealed sleeve therein for arrangement of a mixing device. The volume of the mixing tank is defined by an inner wall of the mixing tank and an inner wall of the sleeve. The mixing tank may be used to mix, store, reconstitute and/or dispense materials therein. Draining of a mixture may be aided with pressurized gas. Heating or cooling of the contents of a mixing tank may be accomplished with a thermal exchange fluid disposed within a thermal exchange vessel and in thermal communication with the tank.