Abstract: A CT system includes a rotatable gantry having an opening for receiving an object to be scanned, and a controller. The controller is configured to apply a first kVp for a first time period, apply a second kVp for a second time period, integrate two or more view datasets during the first time period, integrate one or more view datasets during the second time period, and generate an image using the datasets integrated during the first time period and during the second time period.

Abstract: A CT system includes a generator configured to energize an x-ray source to a first kilovoltage (kVp) and to a second kVp, and a computer that is programmed to acquire a first view dataset with the x-ray source energized to the first kVp and a second view dataset with the x-ray source energized to the second kVp, generate a base correction image using the first view dataset and the second view dataset, and reconstruct a pair of base material images from the first view dataset and from the second view dataset. The computer is also programmed to estimate artifact correlation in the pair of base material images using the base correction image, generate a pair of final base material images and a final monochromatic image, and correct one of the pair of final base material images and the final monochromatic image at a keV value using the estimated artifact correlation.

Abstract: A system and method to image an imaged subject is provided. The system comprises an ultrasound imaging system including an imaging probe operable to move internally and acquire ultrasound image data of the imaged subject, a fluoroscopic imaging system operable to acquire fluoroscopic image data of the imaged subject during image acquisition by the ultrasound imaging system, and a controller in communication with the ultrasound imaging system and the fluoroscopic imaging system. A display can be illustrative of the ultrasound image data acquired with the imaging probe in combination with a fluoroscopic imaging data acquired by the fluoroscopic imaging system.

Abstract: A method for visualizing data includes the step of providing a virtual flight visualization of image data representing a non-landscape object.

Abstract: A method and apparatus are provided for reducing motion related imaging artifacts. The method includes determining an internal motion for of two regions of the object, each region having a different level of motion, scanning the first region using a first scan protocol based on the motion, scanning a second region using a second different scan protocol based on the motion, and generating an image of the object based on the first and second regions.

Abstract: Methods and apparatuses disclosed herein process medical images, for comparison and analysis of the images. The method according to one embodiment accesses digital image data representing a first medical image and a second medical image; registers the second image to the first image using a specific region preserving registration or specific regions preserving registration, to obtain a registered second image; and compares the first image and the registered second image.

Abstract: A method and system for extracting coronary vessels fluoroscopic image sequences using coronary digital subtraction angiography (DSA) are disclosed. A set of mask images of a coronary region is received, and a sequence of contrast images for the coronary region is received. For each contrast image, vessel regions are detected in the contrast image using learning-based vessel segment detection and a background region of the contrast image is determined based on the detected vessel regions. Background motion is estimated between one of the mask images and the background region of the contrast image by estimating a motion field between the mask image and the background image and performing covariance-based filtering over the estimated motion field. The mask image is then warped based on the estimated background motion to generate an estimated background layer. The estimated background layer is subtracted from the contrast image to extract a coronary vessel layer for the contrast image.

Abstract: A method for obtaining an image of tooth tissue directs incident light toward a tooth, wherein the incident light excites a fluorescent emission from the tooth tissue. Fluorescence image data is obtained from the fluorescent emission. Back-scattered reflectance image data is obtained from back-scattered light from the tooth tissue. The fluorescence and back-scattered reflectance image data are combined to form an enhanced image of the tooth tissue for caries detection.

Abstract: An operator designates a reference plane on a medical image or a region of a patient, and a setting unit specifies whether the reference plane is an axial plane, a sagittal plane, or a coronal plane. The setting unit also specifies vertical, horizontal, and anteroposterior directions on the reference plane based on an anatomical characteristic of the region. Information about relationship between a patient coordinate system and a region coordinate system is stored in association with the medical image in a first storage unit.

Abstract: In a medical image processing apparatus according to an embodiment, an image inverting unit generates a first inverted image obtained by inverting a first medical image in a left-and-right direction of an examined subject and generates a second inverted image obtained by inverting a second medical image that is different from the first medical image in the left-and-right direction of the examined subject. A displacement detecting unit detects a displacement between the first medical image and the first inverted image. A registration unit generates, based on the displacement detected by the displacement detecting unit, a corrected image obtained by correcting the second medical image or a corrected inverted image obtained by correcting the second inverted image. A difference image generating unit generates a difference image between the second inverted image and the corrected image or a difference image between the second medical image and the corrected inverted image.

Abstract: A method and an apparatus for motion visualization of a moving object in angiographic images are described. In a preferred embodiment of the method, first a mask image of the object of interest is acquired and a sequence of angiographic images of the object in different phases of motion of the object is acquired. Then, a first angiographic subtraction image and at least a second angiographic subtraction image are generated by subtracting the angiographic images from the mask image. Subsequently, a twice subtracted image is generated by subtracting the first angiographic subtraction image from the second angiographic subtraction image. In this way a double subtraction, i.e. a twice subtracted angiography is performed, to facilitate the assessment of the motion.

Abstract: The invention relates to a method of performing coronary magnetic resonance angiography with signal separation for water and fat, the method comprising: acquiring coronary magnetic resonance angiography datasets using multi-echo Dixon acquisition, processing (314; 316; 318) the datasets for reconstruction of a first (320) and second (322) image data set, the first and second image data set comprising separate water and fat image data, wherein the processing of the datasets comprises a Dixon reconstruction technique.

Abstract: Systems and methods for identifying and analyzing neuropsychological flow patterns, include creating a knowledge base of neuropsychological flow patterns. The knowledge base is formed by obtaining signals from multiple research groups for particular behavioral processes, localizing sources of activity participating in the particular behavioral processes, identifying sets of patterns of brain activity for the behavioral processes and neuropsychologically analyzing the localized sources and the identified patterns for each of the research groups. The neuropsychological analysis includes identifying all possible pathways for the identified sets of patterns, ranking the possible pathways based on likelihood for the particular behavioral process and reducing the number of ranked possible pathways based on additional constraints. A system for comparison of obtained signals from an individual to the created knowledge base is provided.

Abstract: In one embodiment of the invention, there is an ultrasound processing system that communicates images over a single asynchronous serial channel according to a scheme that does not require an isochronous serial channel and that switches among ultrasound imaging modes robustly. For example, the system is configured to packetize ultrasound image data of at least one ultrasound imaging mode into a stream of data frames and to convey the stream of data frames via the asynchronous channel. Each data frame includes indication of the ultrasound imaging mode and includes ultrasound-imaging-mode-specific imaging parameters. Other embodiments exist.

Abstract: An imaging element of a vein imaging apparatus includes a vein image data generation region generating image data of a vein based a near-infrared light that was condensed by a lens array and that was scattered in a living body and transmitted through the vein and a positional displacement detection data generation region that includes a shielded section in which pixels are shielded from the light and an opening section in which pixels are not shielded from the light, and generates data for detecting positional displacement that is used to detect, based on the light received via the opening section, variation in an image focus position according to an imaging temperature. The vein imaging apparatus detects the image focus position of the light and estimates the amount of positional displacement occurred in the apparatus. The vein imaging apparatus selects a pixel based on the obtained amount of positional displacement.

Abstract: A method is disclosed for processing medical image data which image a structure layer by layer, the image data for at least some layers respectively including a plurality of layer images. In at least one embodiment, the method includes segmentation of the structure in the layer images and determination respectively of a position of a point in a layer image. In at least one embodiment, at least one layer image set is furthermore compiled on the basis of the representative points in the layer images.

Abstract: Actual ultrasound attenuation in tissue is used to calculate gain compensation profiles which are used to create a uniform image. Axial, lateral, elevation gain profiles are used to correct the attenuation and ultrasound variation in each direction. In addition, automatic activation of the automatic gain compensation is described.

Abstract: An imaging system includes an x-ray source that emits a beam of x-rays toward an object, a detector that receives high frequency electromagnetic energy attenuated by the object, a data acquisition system (DAS) operably connected to the detector, and a computer operably connected to the DAS. The computer is programmed to compute detector coefficients based on a static low kVp measurement and a static high kVp measurement, capture incident spectra at high and low kVp during fast kVp switching, compute effective X-ray incident spectra at high and low kVp during fast kVp switching using the captured incident spectra, scan a water phantom and normalize the computed detector coefficients to water, adjust the computed effective X-ray incident spectra based on the normalized detector coefficients, compute basis material decomposition functions using the adjusted X-ray incident spectra, and generate one or more basis material density images using the computed basis material decomposition functions.

Abstract: A system and method of extracting at least one time-value curve enables determination of a protocol for a patient in an imaging procedure. The method includes the step of determining a series of 0 through T M-dimensional data sets of pixel values of an imaged portion of the patient acquired using an imaging system. M and T are integers, and the 0 and T data sets correspond to sets at times t=0 and t=T, respectively. Other steps include: computing a predetermined number of correlated segments of the imaged portion corresponding to a number of regions of interest by computing a similarity metric of a time series of pixel values; computing the at least one time-value curve for at least one of those regions; and determining a protocol for a diagnostic scan using the imaging system based at least in part upon data from the at least one time value curve.

Abstract: An imaging system includes an x-ray source configured to emit a beam of x-rays toward an object to be imaged, a detector configured to receive x-rays that are attenuated by the object, a data acquisition system (DAS) operably coupled to the detector, and a computer operably coupled to the DAS and programmed to obtain scan data with two or more incident energy spectra, decompose the obtained scan data into at least three basis materials, generate an image of one of the at least three basis materials using the decomposed scan data, and replace at least one pixel in the image using decomposed data of another of the at least three basis materials.

Abstract: An imaging system includes an x-ray source that emits a beam of x-rays toward an object to be imaged, a detector that receives the x-rays attenuated by the object, a spectral notch filter positioned between the x-ray source and the object, a data acquisition system (DAS) operably connected to the detector, and a computer operably connected to the DAS and programmed to acquire a first image dataset at a first kVp, acquire a second image dataset at a second kVp that is greater than the first kVp, and generate an image of the object using the first image dataset and the second image dataset.

Abstract: A method for detecting tubing in a radiographic image of a patient, executed at least in part by a control logic processor, obtains a radiographic image data for a patient and detects one or more possible tube segments in the image. At least one tubing candidate is formed by growing at least one detected tube segment or merging two or more detected tube segments.

Abstract: The present invention describes a method and system for intelligent diagnostic relevant information processing and analysis. Information associated with a patient is processed via an image reading platform. Based on such processed information, a matrix of diagnosis decisions containing diagnostic related information is generated via a matrix of diagnosis decision platform. A diagnostic decision is made based on the diagnostic relevant information. The image reading platform and/or the matrix of diagnosis decision platform encapsulate information and toolkits to be used to manipulate the information.

Abstract: In MR imaging using a multi-coil device, multifrequency interpolation is combined with a convolution such as BOSCO to achieve simultaneous parallel reconstruction and off-resonance correction. The unaliased and deblurred image is calculated for each coil, and the final image is formed from the images for all of the coils.

Abstract: An image processing apparatus includes: a region detection section which detects a candidate region in which a structure having a predetermined shape is estimated to exist from an image a border pixel detection section which detects a border of the candidate region; a region setting section which sets a local region in the vicinity of and both sides of the border; a feature value calculation section which calculates predetermined feature values based on predetermined values obtained for respective pixel units of the local regions; a discrimination value calculation section which calculates a discrimination value based on calculation results of the predetermined feature values in local region groups on one side and the other side when viewed from the border; and a candidate region correction section which corrects a detection result of a candidate region based on a calculation result of the discrimination value.

Abstract: A method and system are disclosed for creating, in a coordinated manner, graphical images of a body including vascular features from a combination of image data sources. The method includes initially creating an angiographic image of a vessel segment. The angiographic image is, for example, either a two or three dimensional image representation. Next, a vessel image data set is acquired that is distinct from the angiographic image data. The vessel image data set comprises information acquired at a series of positions along the vessel segment. An example of such vessel image data is a set of intravascular ultrasound frames corresponding to circumferential cross-section slices taken at various positions along the vessel segment. The angiographic image and the vessel image data set are correlated by comparing a characteristic rendered independently from both the angiographic image and the vessel image data at positions along the vessel segment.

Abstract: Using nature that a pixel value in a lung of a chest X-ray moving image varies due to heart beat, the variation information on the pixel value is effectively used for diagnosis such as of a lung embolism or a heart disease, considering the variation information as lung blood flow information. A continuous X-ray image screening examination device receives a chest X-ray moving image from an X-ray detector and receives an electrocardiogram to become original information on a heart beat variation from an electrocardiogram recording apparatus. From the dynamic state of the heart wall measured by the electrocardiograph or the chest X-ray moving image, the heart dynamic state during the cardiac chamber systolic and diastolic phases is grasped, and information such as the variation of the pixel value of the chest X-ray moving image due to increase (lung blood flow increase) of the blood flow from the heart to the lung during the cardiac chamber systolic phase is generated.

Abstract: Diagnostic angiograms only provide the projected lumen of a coronary, which is only an indirect measure of blood flow and pressure decline. According to an exemplary embodiment of the present invention, a motion compensated determination of a flow dynamics and a pressure decline for stenosis grading is provided, in which the motion compensation is performed on the basis of a tracking of a first position of a first marker and a second position of a second marker in the projection data set. This may provide for a robust and precise flow dynamics and pressure decline determination.

Abstract: Methods and apparatus provide for marking a location in a medical image, including: providing a first marker within a first medical image, which shows an object, at a first location, determining a second location, which corresponds to the first location, within a second medical image showing the same object, marking the second location with a second marker, which is different to the first marker, and presenting the first medical image, the first marker, the second medical image and the second marker.

Abstract: A method and a device are disclosed for imaging cyclically moving objects using a first and a second imaging method which differ at least with regard to the spatial resolution or the sensitivity. In at least one embodiment of the process, images of the object are continuously recorded by the first imaging method. Temporally different phases of a movement cycle of the object are extracted from the images recorded by the first imaging method. Images of the object are recorded by the second imaging method. The image data recorded in each case in a same, repeating phase of the of the movement cycle by the second imaging method are summed and temporally assigned to the different phases of the movement cycle.

Abstract: A system determines static background medical image data by receiving pixel luminance data comprising multiple sequential medical images of a patient anatomical portion and luminance data of an individual image that comprises multiple pixel luminance representative values of multiple individual pixels of the individual image. A filter includes a first filter function having a first response time for filtering received luminance representative values of a particular individual pixel varying in response to a first motion disturbance in the multiple sequential medical images for use in identifying a substantially minimum luminance value of the particular individual pixel in the multiple sequential medical images. The filter filters luminance representative values of individual pixels of the multiple sequential medical images to identify substantially minimum luminance values of individual pixels in the multiple sequential medical images as background image data of the multiple sequential medical images.

Abstract: Disclosed is a method for determining and displaying at least one piece of information on a target volume, especially in a human body, the information being obtained from an image record. At least one embodiment of the method includes: a first and at least one second image record of a target zone encompassing the target volume are recorded, the first image record having a higher contrast regarding the boundaries of the target volume, and the first and the second image record being registered together; the target volume is segmented in the first image record; target volume image data.

Abstract: An angiography system for angiographic examination or treatment of an organ, vascular system or other regions of an object of a patient is proposed. The system has an x-ray source and an x-ray image detector disposed at ends of a C-arm, a patient support table, a system control unit, an image system, and a monitor. The object contains two details hiding each other in the x-ray images depending on angulation of the C-arm. The system control unit has a device that detects a 3D dataset of the object registered to the C-arm and detects the information about a course of the object. The device calculates a desired and/or optimum angulation of the C-arm from the detected information and transfers the calculated angulation to the system control unit for adjusting the C-arm to the angulation.

Abstract: A method and system for segmenting tubular or stroke-like structures in 2D images is disclosed. Examples of such structures include, but are not limited to, blood vessels, bones, roads, rivers, electrical wirings, and brush-strokes. User inputs identifying a first region on the image inside of a tubular structure and a second region of the image outside of the tubular structure are received. Based on this information, an ordered series of pearls are generated along the tubular structure. Pearls are 2D disks, each having a center location and a radius determined based on local pixel intensities in the image. A continuous model of the tubular structure is generated by interpolating the center locations and radii of the ordered series of pearls.

Abstract: There is provided an image printer having a display unit, in which a predetermined image can be set as a background picture of the display unit. The image printer includes an image processing unit processing an image selected by a user in accordance with a predetermined image processing technique so as to set the selected image as a background picture of the display unit; and a setting unit setting the processed image as the background picture of the display unit, wherein the display unit displays the processed image.

Abstract: A method of generating an enhanced perfusion image comprising the use of a blind deconvolution algorithm and the adiabatic approximation to the Johnson and Wilson model (aaJW) and generation of an image, wherein the blind deconvolution algorithm and the aaJW model are used in the generation of values of the following parameters: voxel specific arterial input function cp[t] and voxel specific tissue residue function r[t].

Abstract: An apparatus provides an image on the basis of a plurality of input images. The apparatus includes a first stage having at least a first and a second combiner, each of the combiners including a first storer for storing image data of the input images, a first processor for processing the image data of the input images into an intermediate image, and a second storer for storing image data of the intermediate image. The apparatus further includes a second stage having at least one further combiner, the further combiner including a third storer for storing image data of those intermediate images which are stored in the second storer of the first stage, a second processor for processing the image data from the third storer, so as to combine the image data of the intermediate images into the image, and a fourth storer for storing image data of the image.

Abstract: An image processing system extracts parts or characteristics of interest from prepared biological samples One suitable use of the image processing system is to find biomarkers. But many other suitable uses are possible. Some components of the system include image preprocessing (data interpolation, retention time alignment, image noise filtering, background estimation, and formation of a composite image); image feature extraction (peaks, isotope groups, and charge groups); and computation of feature characteristics and expression statistics, differential expression, and non-differential expression. Outputs of the system include a candidate list of parts or characteristic of interest for aiding further discovery.

Abstract: An angiography system for angiographic examination of a patient is provided. The system has an x-ray emitter and an x-ray image detector attached to the ends of a C-arm, a patient support couch, a system control unit, an image system and a monitor. The system control unit generates a mask image that detects a reference image, effects a registration of the reference image to the C-arm, whereby if necessary a segmentation of the examination object is implemented in the reference image, contrasts image regions lying inside of the segmentation in order to generate a mask image, and subtracts the mask image from fluoroscopy live images acquired by the angiography system without contrast agent in order to form a roadmap image. The image system effects a reproduction of the roadmap images on the monitor.

Abstract: The present invention describes a method and system for intelligent diagnostic relevant information processing and analysis. Information associated with a patient is processed via an image reading platform. Based on such processed information, a matrix of diagnosis decisions containing diagnostic related information is generated via a matrix of diagnosis decision platform. A diagnostic decision is made based on the diagnostic relevant information. The image reading platform and/or the matrix of diagnosis decision platform encapsulate information and toolkits to be used to manipulate the information.

Abstract: Methods for the improved interactive segmentation of medical image slice data using a computer include the novel combination of the well-known live wire and snakes methods. The improved techniques automatically insert new anchor points for each medical image slice that is processed. The improved methods called iterative live wire and live snakes result in a segmentation process that is faster, more accurate, and requires less operator interaction than the previous methods while still allowing an operator to make adjustments to the segmentation as the process moves from one image slice to the next.

Abstract: A medical image diagnosing support apparatus comprises: a first extraction means which extracts a body region of a subject from a tomographic image of the subject acquired by a medical tomographic apparatus; a second extraction means which extracts a non-adipose region from the body region; a third extraction means which extracts a total body adipose region from the body region; a separation means which separates the total body adipose region into a visceral adipose region and a subcutaneous adipose region based on positional information of the non-adipose region; and a display control means which controls of displaying the tomographic image on an image display device with clear indication of the visceral adipose region and the subcutaneous adipose region.

Abstract: Apparatus and methods are described for use with an image of blood vessels of a subject. In response to a user designating a single point on the image (a) a target portion of a blood vessel is automatically identified in the vicinity of the designated point, and (b) quantitative vessel analysis is performed on the target portion of the blood vessel. An output is generated based upon the quantitative vessel analysis. Other embodiments are also described.

Abstract: Systems and methods for analyzing ratiometric data, e.g., ratiometric image data such as fluorescent image data, may generate a correlation matrix for the ratiometric data, generate a plurality of eigenvalues and a plurality of eigenvectors based on the correlation matrix, select a set of eigenvectors from the plurality of eigenvectors, and reconstruct a set of enhanced ratiometric data for use in analysis.

Abstract: A method of detecting blood vessel shadows in an anterior posterior x-ray radiograph comprising the steps of: generating candidate sub areas of the radiograph showing changes in contrast above a threshold level; supressing rib shadow edges; eliminating lung tissue shadow edges, and categorizing and eliminating nodule shadows.

Abstract: A technique is disclosed for generating a new contour and/or a 3D surface from contour data using a surface displacement field. The technique is preferably applied to un-contoured target images within a 4D image sequence for which contour data is desired. The technique can be initialized with contour data related to a reference image that has already been contoured, e.g. by a doctor who manually enters contour information into a computer. Image registration (calculation of correspondence between the reference image and target image) can be performed simultaneously with segmentation (identifying regions of interest in the target image). This allows one to make use of segmentation information in a reference image to improve the accuracy of contouring within the target image.

Abstract: In differential and non-differential analyses, composite images derived from replicates of liquid-chromatography/mass-spectrometry processes can provide scientists with a better signal-to-noise ratio in discovering biological features of interest. Certain distinct peaks in composite images point to distinct biological features but some distinct peaks in composite images may also point to biological features that have common chemical species ancestry. A peak reassembly process is used to indicate whether two adjacent peaks should point to a biological feature using complementation analysis and collision analysis.

Abstract: A method of fluorescence imaging is provided. The method provides for simultaneously acquiring image data at a plurality of phases and a plurality of frequencies from a region of interest, identifying at least one desired signal and at least one background signal in the acquired image data associated with the region of interest, constructing a digital filter based upon the at least one desired signal and the at least one background signal, wherein the digital filter is configured to enhance image contrast and applying the digital filter to the acquired image data associated with the region of interest to enhance image contrast in the acquired image data. Systems and computer programs that afford functionality of the type defined by this method are also provided.

Abstract: Disclosed herein are methods, computer systems and computer program products for labeling components. One method includes the step of labeling (130) with a current label all voxels that are internal to a predetermined sub-volume oriented with respect to an unlabeled voxel, and directly connected to the unmarked voxel. The labeling step is repeated for all voxels that are not internal to the predetermined sub-volume, but which are labeled with a current label. The method includes the step of incrementing the current label and may include the step of increasing a window size to a predetermined maximum. The preceding steps are repeated for remaining unlabeled object voxels.

Abstract: The invention relates to a method and a device for determination of an optimum direction of projection or position for recording a number of two-dimensional projection images of an object of interest, with the two-dimensional projection images being recorded by rotation or translation of an imaging system around the object. Inventively the process is as follows: a) estimating a position of the object at a point in time; b) determining at least one optimum imaging view from which the optimum direction of projection and/or position is produced, for the position estimated under a) with the aid of previously determined measurement. Preferably the measurement is expressed as a function of a transformation which is described by a spatial object-imaging system relationship.