Abstract: An 3D printer has a gantry configured to move in a plane substantially parallel to a build plane. The system includes a platen configured to support a part being built in a layer by layer process, wherein the platen is configured to move in a direction substantially normal to the build plane. The system includes a head carriage carried by the gantry wherein the head carriage includes a first support member supporting a retaining mechanism. The retaining mechanism includes at least one member extending from the support member and a camming member rotatably attached to the support member and movable about an axis of rotation. The camming member has arcuate camming surface with an increasing radial distance from the axis of rotation. The system includes at least one print head having a housing with a first side surface configured to engage the at least one member and a second side surface configured to engage the arcuate camming surface.

Abstract: The present invention is related to a system for the heterologous expression of a monoclonal Antibody (mAb) or a fragment or derivative thereof, said system comprising at least one ciliate host cell, and incorporated, into said ciliate host cell, at least one heterologous nucleic acid molecule encoding for said monoclonal Antibody, or a fragment or derivative thereof.

Abstract: A lithographic projection apparatus including a radiation system for providing a projection beam of radiation; a support structure for supporting a patterning device, the patterning device serving to pattern the projection beam according to a desired pattern; a substrate holder having a plurality of protrusions, the extremities thereof defining a substantially flat plane of support for supporting a substantially flat substrate, the substrate holder provided with the ability to provide a pressing force for pressing the substrate against the extremities of the protrusions, the protrusions in an edge zone of the substrate holder arranged to provide a substantially flat overhanging of the substrate in relation to the pressing force of the pressing means; and a projection system for projecting the patterned beam onto a target portion of the substrate.

Abstract: A type bearing band assembly for use in a high speed impact printer comprising a flexible band having a plurality of cylindrical slugs secured to the band outer surface and extending across the width thereof. Each slug has end faces which open into bores or cavities extending axially into the slug. A plurality of type modules are provided, each including a head having front and rear faces. One or more raised type characters are formed on each module front face. A shank extends from each module rear face through a slug end face and is secured in the slug cavity.