Antifungal Or Antibacterial Patents (Class 424/404)
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Patent number: 9549949Abstract: An antiviral agent that contains as an active ingredient a particle of at least one kind of iodide composed of iodine and an element shown in Period 4 to Period 6 and Group 8 to Group 15 of a periodic table or at least one kind of monovalent copper compound. The antiviral agent can be incorporated into a variety of products. The antiviral agent can inactivate a wide range of viruses. The antiviral agent can be designed at a higher degree of freedom in terms of its constituents as compared to conventional antiviral agents. In addition, the antiviral agent can readily exhibit and maintain its antiviral activity because it does not require any pretreatments or special washing processes.Type: GrantFiled: August 31, 2009Date of Patent: January 24, 2017Assignee: NBC MESHTEC, INC.Inventors: Yoshie Fujimori, Tsuruo Nakayama, Tetsuya Sato
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Patent number: 9505027Abstract: A two-step immobilisation of silver nanoparticles on solid substrates using polyethylenimine as an adhesive and a reduction linker, where the primary coating of solid substrates by polyethylenimine occurs followed by production of silver nanoparticles covalently anchored on the polymer surface due to a reduction effect of the polyethylenimine functional groups and therefore, no nanoparticles are released to environment. The method permits working under aqueous conditions, does not use any reducing agents, stabilisers or toxic solvents and can universally be applied for anti-microbial treatments of all types of solid substrates.Type: GrantFiled: July 23, 2012Date of Patent: November 29, 2016Assignee: UNIVERZITA PALACKEHO V OLOMOUCIInventors: Radek Zbo{hacek over (r)}il, Jana Soukupová
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Patent number: 9491933Abstract: The invention can produce an infected nail of an animal and an infected animal model in which the nail plate and nail bed of the nail are sufficiently infected with a superficial fungus which were difficult to be produced in the past, and provides an evaluation method useful for development of a therapeutic agent for intractable infectious diseases such as tinea unguium using the nail and the infected animal model. For producing the infected nail of an animal and the infected animal model infected with a superficial fungus, an immunosuppressive component is administered to an animal in advance to decrease immunocompetence, and then, a superficial fungus is inoculated into the animal, whereby the infected nail of an animal and the infected animal model reflecting clinical manifestation in which the nail plate and nail bed of the nail are sufficiently infected with the superficial fungus can be produced with good reproducibility in a short period of time.Type: GrantFiled: December 25, 2008Date of Patent: November 15, 2016Assignee: POLA PHARMA, INC.Inventors: Nobuo Kubota, Tsuyoshi Shimamura, Saori Nagasaka
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Patent number: 9452242Abstract: Antimicrobial metal ion coatings. In particular, described herein are coatings including an anodic metal (e.g., silver and/or zinc and/or copper) that is co-deposited with a cathodic metal (e.g., palladium, platinum, gold, molybdenum, titanium, iridium, osmium, niobium or rhenium) on a substrate (including, but not limited to absorbable/resorbable substrates) so that the anodic metal is galvanically released as antimicrobial ions when the apparatus is exposed to a bodily fluid. The anodic metal may be at least about 25 percent by volume of the coating, resulting in a network of anodic metal with less than 20% of the anodic metal in the coating fully encapsulated by cathodic metal.Type: GrantFiled: July 22, 2015Date of Patent: September 27, 2016Assignee: Silver Bullet Therapeutics, Inc.Inventors: Houdin Dehnad, Julie Lucero, Paul E. Chirico, Jason A. Jegge, Thomas Lee Gutshall
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Patent number: 9414586Abstract: Foaming alcohol compositions with selected dimethicone surfactants are disclosed. The dimethicone surfactants are PEG-8 to PEG-12 linear dimethicone surfactants and in particular PEG-10 linear dimethicone surfactant. The compositions are useful as antimicrobial products and in particular handcare or skincare products.Type: GrantFiled: September 25, 2014Date of Patent: August 16, 2016Assignee: Ecolab USA Inc.Inventors: Joseph R. Wegner, Cheryl A. Littau
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Patent number: 9403702Abstract: The invention provides systems and methods for purification of fluids such as water and air. The fluids are passed through a filter comprising chlorhexidine citrate (CXC), wherein either in the same filter or downstream from it a sorbing mixture of porous calcium phosphate, calcium carbonate and activated carbon is also provided. The invention enables rapid, economical fluid purification without byproducts. The materials can be regenerated for reuse, and the invention can be used for either high volume applications or disposable single-use applications.Type: GrantFiled: September 17, 2015Date of Patent: August 2, 2016Assignee: A BETTER LIFE WORLDWIDE, LLCInventors: Arthur W. Johnston, Arthur F. Johnston
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Patent number: 9364431Abstract: The present invention provides an infused carbohydrate based gel pad comprising: glucose polymer syrup, sugar, a hydrocolloid gelling agent, salt, acid, water and an infusing compound for oral transmucosal delivery wherein the gel pad (i) provides transmucosal delivery of active ingredients of the infusing compound into the bloodstream over a predetermined period of time; and (ii) possesses the property of adhesion to gum line tissue of an oral cavity and lack of adhesion to buccal tissue of the oral cavity. The present invention further provides a method of making the infused carbohydrate based gel.Type: GrantFiled: July 9, 2013Date of Patent: June 14, 2016Inventor: Terence Vincent Callahan
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Patent number: 9326504Abstract: The disposable antibacterial liner is a skin covering that provides a protective barrier between the skin and the personal protective equipment. The disposable antibacterial liner is a sheath that is worn between the skin and the personal protective equipment. The sheath is treated with an antimicrobial finish that both 1) acts as a prophylaxis that protects the skin from infection; and, 2) treats the personal protective equipment 133 with the antimicrobial finish to help keep the personal protective equipment 133 clean. The disposable antibacterial liner comprises a sheath and an antimicrobial finish. Alternate embodiments of the disclosure further comprise a container and perforations within the sheath.Type: GrantFiled: June 23, 2015Date of Patent: May 3, 2016Inventor: Christine Graziano
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Patent number: 9125768Abstract: A hygiene tissue (1), such as a wet wipe, dry wipe, washcloth, patch, towelette, napkin, and the like includes a microbe-inhibiting composition (8). The microbe-inhibiting composition (8) includes an extracellular product of at least one probiotic bacterium and at least one additive in the form of an organic acid, with at least one of its pKa value not exceeding 5.5, and/or a salt thereof.Type: GrantFiled: November 17, 2006Date of Patent: September 8, 2015Assignee: SCA HYGIENE PRODUCTS ABInventors: Ulrika Husmark, Ulla Forsgren Brusk
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Patent number: 9084764Abstract: In one aspect, an epidermal coolant includes a porous material and a phase change material retained in the porous material. The phase change material has a melting point between about 0-degrees Celsius and about 65-degrees Celsius and is retained in the porous material when the phase change material is in either the solid or liquid phase. In another aspect, an epidermal coolant dispensable by an aerosol container includes a phase change material that changes phase between about 28-degrees and 40-degrees Celsius. The coolant also includes a solvent in which the phase change material is dissolved and a surfactant. The coolant may further include a propellant to express the product from the aerosol container.Type: GrantFiled: August 16, 2012Date of Patent: July 21, 2015Assignee: Exert Co.Inventor: Arvind M. Rao
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Patent number: 9060511Abstract: A biocidal composition comprising 2,2-dibromomalonamide and a metal selected from silver, copper, and mixtures thereof, and its use for the control of microorganisms in aqueous and water-containing systems.Type: GrantFiled: August 3, 2011Date of Patent: June 23, 2015Assignees: Rohm and Haas Company, Dow Global Technologies LLCInventors: Freddie L. Singleton, Tirthankar Ghosh, Kimberly S. Cagle
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Patent number: 9028852Abstract: Antimicrobial compositions, especially those useful when applied topically, particularly to mucosal tissues (i.e., mucous membranes), including a cationic antiseptic such as biguanides and bisbiguanides such as chlorhexidine and its various salts including but not limited to the digluconate, diacetate, dimethosulfate, and dilactate salts; polymeric quaternary ammonium compounds such as polyhexamethylenebiguanide; silver and various silver complexes; small molecule quaternary ammonium compounds such as benzalkoium chloride and alkyl substituted derivatives; di-long chain alkyl (C8-C18) quaternary ammonium compounds; cetylpyridinium halides and their derivatives; benzethonium chloride and its alkyl substituted derivatives; and octenidine. The compositions can also include an enhancer component, a surfactant, a hydrophobic component, and/or a hydrophilic component.Type: GrantFiled: September 7, 2004Date of Patent: May 12, 2015Assignee: 3M Innovative Properties CompanyInventor: Matthew T. Scholz
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Patent number: 9028853Abstract: A moisture-permeable glove or other garment protects against user contamination and cross-contamination by providing both rapid and persistent sterilization. Exposure to halogen of inherent NH groups and/or attached hydantoin can form a persistent outer halamine sterilization layer. A second inner halamine layer intercepts any pathogens that penetrate the outer surface. The garment can be single layer, or can include a detachable inner liner. Embodiments are compatible with rapid decontamination using an alcohol-based agent. Some embodiments provide a 180 second 3-log kill rate for at least S. aureus ATCC and E. coli. Embodiments include a moistening agent to activate the halamine. An anti-cut/puncture layer and/or a pathogen barrier layer can also be included. The protective layer can include contiguous layers of soft and hard metal flexed to improve flexibility and Moisture Vapor Transport Rate (MVTR). The pathogen barrier can include urethane and/or CNT fibers. The garment MVTR can be greater than 0.Type: GrantFiled: May 10, 2012Date of Patent: May 12, 2015Assignee: Warwick Mills Inc.Inventor: Charles A. Howland
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Patent number: 9028876Abstract: Rate-controlled particles, comprising compounds of the formula as a solid dispersion.Type: GrantFiled: March 14, 2012Date of Patent: May 12, 2015Assignee: Janssen R&D IrelandInventors: Thomas Hantke, Bettina Rehbock, Jörg Rosenberg, Jörg Breitenbach
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Publication number: 20150110843Abstract: Fibrous antimicrobial materials for use in structures and barrier applications, such as face masks and wound dressings, have been developed from antimicrobial polymeric materials. The fibrous antimicrobial materials also are particularly suitable for use in air and water filtration. The antimicrobial polymeric materials are prepared from solid solutions of antimicrobial bisguanide compounds blended with certain thermoplastic polymers. The antimicrobial polymeric materials may be extruded into fibers or used in the particulate form for preparation of the nonwoven antimicrobial materials. The antimicrobial bisguanide compound, such as chlorhexidine, are distributed at the molecular level within at least one thermoplastic polymer, such as a polyolefin in which the antimicrobial bisguanide compound is soluble, to form a miscible blend. Methods for their formation and use also are provided.Type: ApplicationFiled: December 23, 2014Publication date: April 23, 2015Inventors: Jan W. Gooch, Thomas J. Steimer, SR.
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Patent number: 9011890Abstract: Antibacterial sol-gel coating solutions are used to form articles. The antibacterial sol-gel coating solution includes at least one Ti or Si-containing compound that is capable of hydrolyzing to form a base film; a regulating agent capable of regulating the hydrolysis rate of the Ti or Si-containing compounds, an organic solvent, water, and at least one soluble compound of an antibacterial metal, such as Ag, Cu, Mg, Zn, Sn, Fe, Co, Ni, or Ce.Type: GrantFiled: December 12, 2005Date of Patent: April 21, 2015Assignee: Qinhuangdao Yipeng Special Glass Co., Ltd.Inventors: De-xian Wang, Zhen-yu Lei
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Patent number: 8968773Abstract: The invention provides: a cross-linkable therapeutic composition comprising a) a saccharide-siloxane copolymer; b) a crosslinking agent; c) one or more active/inactive ingredients; and d) optionally, a solvent, or solvent mixture, wherein the saccharide-siloxane copolymer has the following formula: R2aR1(3-a)SiO—[(SiR2R1O)m-(SiR12O)n]y-SiR1(3-a)R2a that is further formulaically defined and wherein the saccharide-siloxane copolymer is a reaction product of a functionalized organosiloxane polymer and at least one hydroxy-functional saccharide such that the organosiloxane component is covalently linked via a linking group to the saccharide component; films; and methods related thereto. The composition has therapeutic properties. The invention also provides articles of manufacture including topical and transdermal agent delivery patches comprising the novel film-forming composition and/or films.Type: GrantFiled: May 23, 2007Date of Patent: March 3, 2015Assignee: Dow Corning CorporationInventors: Xavier Thomas, Virginie Caprasse, Eric Jude Joffre, Csilla Kollar, David Clayton Gantner, Victor A. Raul
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Patent number: 8968793Abstract: Antiseptic compositions and kits containing a source of silver ions and menthol, which act in synergy such that a concentration of silver ions in the composition is substantially reduced, are disclosed. Further disclosed are uses of the antiseptic compositions as disinfectants and in the treatment of wounds.Type: GrantFiled: February 11, 2010Date of Patent: March 3, 2015Assignee: Ramot at Tel-Aviv University Ltd.Inventors: Noa Hadar, Amihay Freeman
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Patent number: 8968794Abstract: Antiseptic compositions and kits containing a source of silver ions and menthol, which act in synergy such that a concentration of silver ions in the composition is substantially reduced, are disclosed. Further disclosed are uses of the antiseptic compositions as disinfectants and in the treatment of wounds.Type: GrantFiled: March 1, 2011Date of Patent: March 3, 2015Assignee: Ramot at Tel-Aviv University Ltd.Inventors: Noa Hadar, Amihay Freeman
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Patent number: 8962669Abstract: An object is to provide a medicament preparation which is excellent in the solubilization stability in relation to a compound represented by the general formula (1) during the storage in a low temperature region and a high temperature region. The present invention resides in a pharmaceutical composition comprising 1) the compound represented by the general formula (1) and/or a salt thereof and 2) a polyhydric alcohol derivative. General formula (1) (In the formula, R1, R2 independently represent hydrogen atom or halogen atom respectively, and at least one of R1, R2 is halogen atom.Type: GrantFiled: June 10, 2011Date of Patent: February 24, 2015Assignees: Pola Pharma Inc., Nihon Nohyaku Co., Ltd.Inventors: Nobuo Kubota, Hirokazu Kobayashi, Takaaki Masuda
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Patent number: 8952044Abstract: A pharmaceutical composition which comprises 1) a compound represented by the following general formula (1) and/or a salt thereof; and 2) a ketone such as methyl ethyl ketone. Preferably, the compound represented by the following general formula (1) is luliconazole, where R1?R2=a chlorine atom: where R1 and R2 each independently represents a hydrogen atom or a halogen atom, and at least one of R1 and R2 represents a halogen atom. The present invention provides a preparation excellent in solubilization stability for a compound represented by the general formula (1) and/or a salt thereof in low-temperature or high-temperature storage.Type: GrantFiled: July 29, 2010Date of Patent: February 10, 2015Assignees: Pola Pharma Inc., Nihon Nohyaku Co., Ltd.Inventors: Hirokazu Kobayashi, Nobuo Kubota
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Publication number: 20150037384Abstract: A material includes a bamboo-based, water-absorbent fabric layer defining an exposed first surface and a second, opposite surface. A water-resistant, antibacterial coating layer covers the second surface of the fabric layer. The material is both water-absorbent and water-resistant, comfortable, recyclable, sanitary, machine washable, drier safe, and environmentally friendly. Such material may be utilized in items such as exercise mats and equipment; household items (both indoor and outdoor) such as rugs, floor mats, place mats, mattress covers, pillow cases, shower curtains, etc.; clothing; footwear; personal accessories; medical drapes, mats, and coverings; etc.Type: ApplicationFiled: August 2, 2013Publication date: February 5, 2015Inventor: Ashley Cintas
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Patent number: 8940797Abstract: Foaming alcohol compositions with selected dimethicone surfactants are disclosed. The dimethicone surfactants are PEG-8 to PEG-12 linear dimethicone surfactants and in particular PEG-10 linear dimethicone surfactant. The compositions are useful as antimicrobial products and in particular handcare or skincare products.Type: GrantFiled: November 20, 2013Date of Patent: January 27, 2015Assignee: Ecolab USA Inc.Inventors: Joseph R. Wegner, Cheryl A. Littau
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Publication number: 20150024017Abstract: A solid buffer including one or more ion exchange materials, wherein said solid buffer has a volumetric buffering capacity greater than about 20 mM H+/(L·pH unit) and further wherein, when said material is in an environment capable of transporting H+ ions, said solid buffer is adapted to cause the death of at least one target cell within or in contact with said environment. A selectively permeable barrier layer may be provided covering the solid buffer.Type: ApplicationFiled: April 11, 2014Publication date: January 22, 2015Applicant: OPLON PURE SCIENCE, LTD.Inventors: Shmuel BUKSHPAN, Gleb ZILBERSTEIN
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Publication number: 20140348890Abstract: The invention relates to a wound dressing having a backing and an antimicrobial wound contact layer, wherein the wound contact layer has a hydrophobized active ingredient.Type: ApplicationFiled: August 8, 2014Publication date: November 27, 2014Applicant: LOHMANN & RAUSCHER GMBH & CO. KGInventor: MARIUS-THOMAS GORKA
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Patent number: 8889163Abstract: Facially amphiphilic polyphenylene and heteroarylene polymers and articles made therform having biocidal surfaces are disclosed. The polymers can inhibit the growth of microorganisms in contact with the surface or in areas adjacent to said biocidal surface. There is also disclosed a methods to attach facially amphiphilic polmers to a solid support. Utility as a contact disinfectant is disclosed.Type: GrantFiled: March 7, 2002Date of Patent: November 18, 2014Assignee: The Trustees of the University of PennsylvaniaInventors: William F. DeGrado, Gregory N. Tew, Michael L. Klein
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Patent number: 8889038Abstract: This invention relates to wood preservatives containing copper complexes and calcium ions, zinc ions or calcium and zinc ions for protection of wood, cellulose, hemicellulose, lignocellulose, cellulosic materials and articles derived from cellulosic materials from decay caused by fungi. The calcium ions, zinc ions, or calcium and zinc ions improve the penetration of copper preservative agent into the interior of a treated material or article.Type: GrantFiled: December 18, 2008Date of Patent: November 18, 2014Assignee: E I du Pont de Nemours and CompanyInventors: Albert Gordon Anderson, Mark A. Scialdone
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Publication number: 20140326192Abstract: The invention provides an article for use with an animal, particularly a domesticated animal, comprising an antimicrobial agent and a polymer, wherein the antimicrobial agent is a quaternary ammonium compound. More specifically, the invention provides articles, such as grooming tools, for equestrian use which are capable of preventing the spread of diseases such as strangles, ringworm and diseases associated with Mycotoxins such as Fusarium.Type: ApplicationFiled: November 30, 2012Publication date: November 6, 2014Inventors: Stephen Coupe, Gracy Sailo-Lebeau
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Patent number: 8871233Abstract: Topical sanitizer includes avenanthramides, which is an active component of oats that is beneficial to the skin. The topical sanitizer is used preferably in conjunction with gloves that have an inner coating that includes avenanthramides. By using topical sanitizer that includes avenanthramides before and after wearing gloves, the skin of the person wearing the glove is more exposed to the beneficial avenanthramides all during the workday, not just when wearing gloves. The result is healthier, much softer and more comfortable skin on the hands.Type: GrantFiled: April 16, 2013Date of Patent: October 28, 2014Assignee: The Idea Folder LLCInventors: Mark James Redmond, Joseph H. Neuser
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Patent number: 8871232Abstract: A wipe that includes a bacteriostatic agent that contains cations having an affinity for the negatively charged cell walls of bacteria is provided. The affinity of the bacteriostatic agent for the bacteria allows the wipe to capture bacteria, thereby removing them from a surface and also inhibiting their spread to other surfaces that may contact the wipe. Of particular advantage, the bacteriostatic agent may help protect against the spread or infection of pathogens without the use of chemicals, such as antiseptics or antibiotics. Still further, the wipe of the present invention also contains a solvatochromatic indicator that undergoes a color change in the presence of a broad spectrum of bacteria. Thus, when the wipe captures bacteria, the indicator undergoes a color change that signals to the user that the wipe is functioning properly. The lack of a color change may likewise provide the user with the assurance that the area is generally free of bacteria and clean.Type: GrantFiled: December 13, 2007Date of Patent: October 28, 2014Assignee: Kimberly-Clark Worldwide, Inc.Inventors: Stephanie M. Martin, John Gavin MacDonald, Bao Trong Do
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Publication number: 20140308326Abstract: Pharmaceutical compositions comprising an aminoglycosidic antibiotic and at least one zinc-chelating agent in a specified concentration, and methods of inhibiting bacterial colonization, biofilm formation and if treating bacterial infections utilizing the compositions are provided. Topical formulations suitable for wound care, and surface-applicable formulations suitable for medical, industrial and household disinfecting needs are also described.Type: ApplicationFiled: April 16, 2014Publication date: October 16, 2014Applicant: UNIVERSITY OF CINCINNATIInventors: Andrew B. HERR, Stephan DAVIS, Gary YOUNG
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Patent number: 8858971Abstract: In one aspect, an epidermal coolant dispensable by an aerosol container includes a phase change material that changes phase between about 28-degrees and 40-degrees Celsius. The coolant also includes a solvent in which the phase change material is dissolved and a surfactant. The coolant may further include a propellant to express the product from the aerosol container. In another aspect, an epidermal coolant includes a porous material and a phase change material retained in the porous material. The phase change material has a melting point between about 0-degrees Celsius and about 65-degrees Celsius and is retained in the porous material when the phase change material is in either the solid or liquid phase.Type: GrantFiled: June 20, 2013Date of Patent: October 14, 2014Assignee: Exert Co.Inventor: Arvind M. Rao
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Patent number: 8852617Abstract: A dental care preparation in a form of a toothpaste or tooth gel dentifrice includes an antimicrobial amount of at least one antimicrobial N-methylol transfer agent, and at least one of a fluoride compound or a source of fluoride ions.Type: GrantFiled: September 26, 2011Date of Patent: October 7, 2014Assignee: Geistlich Pharma AGInventors: Rolf W. Pfirrmann, Peter Geistlich
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Publication number: 20140294905Abstract: This invention is about textiles which are equipped with antifungal, anticandidal and antibacterial properties. The aim of the invention is to attain antimicrobial textiles which reduces the incidence of infections communicated or spread by textiles, reduces the loss of extra cost and energy to ensure hygiene and strengthens the hygienic condition of disposable textiles. Textiles can be equipped with antimicrobial properties in three ways: In the first method, sodium borate is dissolved in methanol and is then fixed to the fabric. In the second method, sodium borate is dissolved in water and is then sprayed onto the fabric. In the third method, sodium borate dissolved in water and mixed with textile dye and applied as a dye. Antimicrobial properties of sodium borate are tested on 38 bacterial species, 9 yeasts and 1 1 fungi isolates based on disc diffusion assay.Type: ApplicationFiled: November 16, 2012Publication date: October 2, 2014Inventors: Fikrettin Sahin, Selami Demirci, Zeynep Ustaoglu
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Publication number: 20140271755Abstract: A garment treated with an antimicrobial agent that causes the garment to repel foreign objects when exposed to sunlight.Type: ApplicationFiled: March 15, 2013Publication date: September 18, 2014Inventor: William C. Busch
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Patent number: 8809210Abstract: A self-decontaminating fabric is manufactured from fibers such as Tencel having high surface energy and low surface roughness. Novel scouring methods eliminate substantially all contaminants from the fibers, and a novel coating process applies an anti-pathogen coating such as a halogen compound to the fabric so as to provide rapid deactivation of pathogens on contact. Novel charging methods activate or reactivate the coating, typically by exposure to chlorine. The coating is substantially free of gap regions where pathogens can survive. The high surface energy of the fibers allows a high coating concentration and provides close contact between attached pathogens and the coating. The low surface roughness reduces the pickup of pathogens by the fibers. Multi-layer embodiments include an outer layer configured for maximum anti-pathogen coating concentration, and an inner layer configured for a reduced coating concentration that is compatible with skin contact.Type: GrantFiled: June 28, 2012Date of Patent: August 19, 2014Assignee: Warwick Mills, Inc.Inventor: Charles A Howland
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Patent number: 8795697Abstract: The invention provides a sanitizing composition in the form of a viscous liquid or gel suitable for use as a handwash composition comprising alcohol, water and a thickener wherein the viscous liquid or gel has particles suspended therein, wherein said particles provide the composition with a granular texture and are capable of being worn away when rubbed. The particles may deliver one or more agents to the skin e.g. antimicrobial, antibacterial or antiviral agents, emollients and/or moisturizers, fragrances, colorings or UV markers.Type: GrantFiled: April 9, 2005Date of Patent: August 5, 2014Inventor: James S. Brown
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Patent number: 8790671Abstract: Anhydrous agents for topical application, comprising one or more C1-C4 alkyl esters of lactic acid, malic acid, tartaric acid or citric acid and physiologically acceptable excipients, are described for the treatment of nail disorders caused by mycoses and for nail care. The agents according to the invention are also suitable in veterinary medicine for treating fungal infections of the hooves, claws and talons of pets and farm animals and wild animals living in captivity.Type: GrantFiled: April 3, 2008Date of Patent: July 29, 2014Assignee: Bioequal AGInventor: Hans Meyer
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Patent number: 8790686Abstract: A hemorrhoid-treating composition comprising gentian violet and a lubricant or suppository base. A method of treating hemorrhoids by topically applying a composition comprising gentian violet and a lubricant or suppository base.Type: GrantFiled: April 14, 2005Date of Patent: July 29, 2014Inventor: L. Gaye Carroll
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Publication number: 20140205639Abstract: The present invention relates to pharmaceutical compositions suitable for the topical treatment of fungal infections of the skin and nails, such as tinea pedia and tinea cruris, among others. The active ingredients of the present compositions are low molecular weight organic acids and their salts, many of which are previously known as antifungal agents to some degree but which, when used in combination, produce a synergistic enhancement in antifungal potency such that the combined effect is greater than that when used by the agents alone. The antifungal activity of the active ingredients is further enhanced through the use of non-volatile hygroscopic solvents rather than the aqueous or volatile organic solvents used in the art.Type: ApplicationFiled: January 22, 2013Publication date: July 24, 2014Applicant: bioCEPTA CorporationInventor: Peter Mladenovich
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Patent number: 8785399Abstract: The present invention relates to monomeric and multimeric peptidic compounds which have antimicrobial activity, particularly against Gram-positive and Gram-negative bacteria. Further, the present invention refers to compositions comprising said peptidic compounds for medical use, for use as a disinfectant and/or detergent or for use as a preservative.Type: GrantFiled: June 2, 2009Date of Patent: July 22, 2014Assignee: Spiderbiotech S.R.A.Inventors: Andrea Giuliani, Giovanna Pirri, Silvia Fabiole Nicoletto
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Patent number: 8765806Abstract: Provided is a biocidal composition comprising 2,6-dimethyl-m-dioxane-4-ol acetate and an isothiazolinone biocidal compound. The composition is useful for controlling microorganisms in aqueous or water containing systems.Type: GrantFiled: November 17, 2009Date of Patent: July 1, 2014Assignee: Dow Global Technologies LLCInventors: Ioana Annis, Jon B. Raymond, Emerentiana Sianawati
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Patent number: 8764715Abstract: Test methods for assessing irritation of portions of skin are provided. The method may include irritating a portion of skin by contacting the portion of skin with a chemical irritant; irritating the portion of skin by physical irritation; and assessing erythema or dryness of the portion of skin after irritating the steps. Alternatively, the method may include irritating a portion of skin with a chemical irritant; irritating the portion of skin by physical irritation; treating the irritated portion of skin by wiping the irritated portion of skin with a test sample; and assessing erythema or dryness of the portion of skin after the wiping step. A method of irritating a portion of skin to assess one of erythema and dryness may include irritating a portion of skin with a chemical irritant and irritating the portion of skin by physical irritation.Type: GrantFiled: July 28, 2011Date of Patent: July 1, 2014Assignee: The Procter & Gamble ComapnyInventor: Miranda Aref Farage
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Patent number: 8741349Abstract: In one embodiment, an antiviral material includes at least one microparticles selected from tungsten oxide microparticles and tungsten oxide composite microparticles. The microparticles have an inactivation effect R of 1 or more expressed by [R=log C?log A], when there is evaluated a virus titer by inoculating on a specimen to which the microparticles are adhered, at least one virus selected from a low pathogenic avian influenza virus (H9N2), a high pathogenic avian influenza virus (H5N1) and a swine influenza virus, and irradiating the specimen with visible light having a wavelength of 380 nm or more and illuminance of 6000 1× for 24 hours.Type: GrantFiled: February 9, 2012Date of Patent: June 3, 2014Assignees: Kabushiki Kaisha Toshiba, Toshiba Materials Co. Ltd.Inventors: Kayo Nakano, Akira Sato, Takao Kusaka, Shinya Kasamatsu, Akito Sasaki, Daisuke Fukushi
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Patent number: 8735393Abstract: The present invention provides anhydrous compositions for topical delivery of a medicament comprising (A) a penetration enhancer/solvent selected from the group consisting of alcohol, propylene glycol, or a combination thereof; (B) a humectant/solvent selected from the group consisting of polyethylene glycol, glycerin, sorbitol, xylitol, or any combination of any of the foregoing; and (C) an anhydrous vehicle. In an alternate embodiment, the present invention provides anhydrous compositions for topical delivery of a medicament which comprise (A) a penetration enhancer/solvent selected from the group consisting of alcohol, propylene glycol, or a combination thereof; (B) a humectant/solvent selected from the group consisting of polyethylene glycol, glycerin, sorbitol, xylitol or any combination of any of the foregoing; (C) an anhydrous vehicle; and (D) a medicament. Also provided are methods for topically delivering a medicament to an animal.Type: GrantFiled: July 27, 2012Date of Patent: May 27, 2014Assignee: Johnson & Johnson Consumer Companies, Inc.Inventors: Katherine M. Burnett, Ellen S. Kurtz
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Patent number: 8728513Abstract: A wound dressing having anti-microbial activity comprises a first fiber capable of bonding with silver (1) cations. The wound dressing comprises a blend of the first fiber to which silver (1) cations are bonded and a second fiber which is substantially free from silver. The wound dressing comprises from 0.01 to 5.0 percent by weight of silver (1) cations, based on the weight of fiber.Type: GrantFiled: February 14, 2013Date of Patent: May 20, 2014Assignee: Convatec Technologies Inc.Inventor: David Malcolm Woods
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Publication number: 20140127276Abstract: A method for removing airborne bacteria and airborne mycetes from indoor air comprises imparting microbiocidal and microbiostatic properties to fabric by treating the fabric with one or more naturally occurring biocides, positioning the treated fabric in a sheet-like orientation, and blowing indoor air through the fabric.Type: ApplicationFiled: February 15, 2013Publication date: May 8, 2014Applicant: PHILADELPHIA UNIVERSITYInventors: Diana R. Cundell, Brian R. George
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Patent number: 8715701Abstract: Protein preparations containing biologically active compounds and the application of the protein preparations obtained, particularly as a component of medicinal and cosmetic preparations as protective substances or in the regeneration of cells and tissues of the human organism, and which can comprise a component of culture media for dermal or hepatic tissues, or for stem cells destined for use in the regeneration of cells and tissues in the human organism.Type: GrantFiled: November 20, 2007Date of Patent: May 6, 2014Assignee: Instytut Medycyny Doswiadczalnej I KlinicznejInventors: Andrzej Lipkowski, Anna Grabowska, Katarzyna Kurzepa, Aleksandra Szczucinska
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Publication number: 20140120145Abstract: A process is described herein for applying antimicrobials to substrates such as fabrics. An antimicrobial-binder mixture is provided that includes an antimicrobial and a binder that includes guar gum in an aqueous solution, which is applied to the substrate. Once the substrate is cured, spikes formed by the antimicrobial are disposed on the fabric and function to rupture membranes of infectious agents.Type: ApplicationFiled: October 26, 2012Publication date: May 1, 2014Inventor: Joseph Giovanniello
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Patent number: 8697102Abstract: A solid buffer including one or more ion exchange materials, wherein said solid buffer has a volumetric buffering capacity greater than about 20 mM H+/(L.pH unit) and further wherein, when said material is in an environment capable of transporting H+ ions, said solid buffer is adapted to cause the death of at least one target cell within or in contact with said environment. A selectively permeable barrier layer may be provided covering the solid buffer.Type: GrantFiled: June 25, 2010Date of Patent: April 15, 2014Assignee: Oplon B.V.Inventors: Shmuel Bukshpan, Gleb Zilberstein