Ferment Containing (e.g., Enzymes, Bacteria, Etc.) Patents (Class 424/50)
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Publication number: 20140377192Abstract: Described herein are oral care compositions comprising an effective amount of an enzyme cocktail, wherein the enzyme cocktail comprises an alkaline protease and a second enzyme selected from cellulase, ?-glucanase, and combinations thereof, in an orally acceptable carrier, together with methods of making and using the same.Type: ApplicationFiled: December 21, 2011Publication date: December 25, 2014Applicant: COLGATE-PALMOLIVE COMPANYInventors: Lyndsay Schaeffer-Korbylo, Jason Nesta, Laurence Du-Thumm
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Publication number: 20140348760Abstract: Described herein are oral care compositions comprising (i) a magnesium alkali metal silicate complex clay, and (ii) an orally acceptable anionic polymer, in a dentifrice base, which compositions are useful for alleviating dental sensitivity. Also provided for, are methods of making and using the compositions described herein.Type: ApplicationFiled: December 21, 2011Publication date: November 27, 2014Applicant: Colgate-Palmolive CompanyInventors: Suman Chopra, Lin Fei, Rahul Patel
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Patent number: 8894977Abstract: The present invention encompasses an oral treatment composition containing an anti-adhesion agent, preferably a cysteine protease and most preferably ficin. In another aspect, the cysteine protease is in combination with one or more ingredients, such as antibacterial agent and surfactant. The anti-adhesion agent mitigates interaction between a subject oral cavity and plaque-forming materials.Type: GrantFiled: September 29, 2005Date of Patent: November 25, 2014Assignee: Colgate-Palmolive CompanyInventors: Harsh M. Trivedi, Tao Xu, Ramachandra Shastry, James Masters, André Michelle Morgan
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Patent number: 8895019Abstract: The invention provides a method of preventing, inhibiting or reducing a P. gingivalis biofilm in a subject comprising administering to the subject a pharmaceutical composition comprising an inhibiting agent of a polypeptide that reduces or inhibits biofilm formation and/or biofilm development. Also provided are compositions useful in the prevention, inhibition or treatment of periodontal disease or P. gingivalis infection.Type: GrantFiled: July 13, 2012Date of Patent: November 25, 2014Assignee: Oral Health Australia Pty LtdInventors: Stuart Geoffrey Dashper, Eric Charles Reynolds, Paul David Veith, Ching Seng Ang
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Patent number: 8889106Abstract: A non-alcohol mouthwash composition without chemical antibacterial medicament is disclosed. The non-alcohol mouthwash composition includes from 0.03% to 1.5% of ?-polyglutamic acid (?-PGA) and from 0.5% to 4% of surfactant, all percentages based on the total weight of the mouthwash composition. The non-alcohol mouthwash composition preferably includes from 0.4% to 1.5% by weight, or more preferably from 0.8% to 1.3% by weight, of ?-PGA. Containing no chemical antibacterial medicament, the non-alcohol mouthwash composition can effectively inhibit bacterial growth in the oral cavity without irritating the oral mucosa.Type: GrantFiled: June 28, 2013Date of Patent: November 18, 2014Inventors: Feng-Huei Lin, Chun-Pin Lin, Hsuan-Yu Chen, Tzu-Piao Tang, Hsu-Wei Fang, Chung-King Hsu, Chia-Ming Chang
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Publication number: 20140314819Abstract: The present disclosure provides methods and compositions for treating or reducing a dental condition in an animal, particularly in canine and feline companion animals. Compositions useful in the disclosed methods comprise an effective amount of lactic acid. The disclosed compositions may also contain oral health promoting effective amounts of at least one antioxidant. Dental conditions treated or reduced according to the disclosed methods include dental plaque, calculus, tooth staining, halitosis, stomatitis, gingivitis, periodontitis, and combinations thereof.Type: ApplicationFiled: August 30, 2012Publication date: October 23, 2014Applicant: HILL'S PET NUTRITION, INC.Inventors: Dale S. Scherl, Dennis Jewell, Philip W. Toll, Kevin A. Hahn
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Publication number: 20140314691Abstract: In various embodiments compositions are provided for the whitening, and/or brightening, and/or restoration of a tooth. In various embodiments the compositions, referred to herein as “dental care” compositions typically comprise a binding moiety that binds to calcium and/or to tooth enamel and/or to pellicle attached to an active agent. The active agent is selected to deliver a particular activity (e.g., whitening, remineralization, desensitization, brightening, etc.) to the tooth.Type: ApplicationFiled: March 11, 2014Publication date: October 23, 2014Applicant: C3 JIAN, INC.Inventors: Randal H. ECKERT, Daniel K. YARBROUGH, Brian C. VARNUM
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Publication number: 20140314686Abstract: Microemulsions and soluble alkali metal salts of relatively insoluble aglycone polyphenols within oral hygienic products are disclosed for treating oral inflammatory disorders. The formulations can act as a bactericide or bacteriostat. The methods include the process associated with the formation of a high temperature polyphenol/surfactant concentrate, a nano-particulate precipitation process in the presence of a surfactant and the solubilization of relatively insoluble aglycone polyphenols/flavonoids by the formation of soluble alkali metal salts within alkaline oral compositions.Type: ApplicationFiled: March 17, 2014Publication date: October 23, 2014Inventors: Philip J. Birbara, Jeffrey Cummings
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Publication number: 20140308217Abstract: Described herein are oral care compositions comprising (i) an orally acceptable gallium salt and (ii) a basic amino acid polymer, in amounts effective to disrupt biofilm; and methods of making and using the same.Type: ApplicationFiled: December 15, 2011Publication date: October 16, 2014Applicant: COLGATE-PALMOLIVE COMPANYInventors: Lyndsay Schaeffer-Korbylo, Christine Cuiule, Laurence Du-Thumm
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Publication number: 20140271763Abstract: Disclosed herein are marine bacterial substances, methods, and medical devices that inhibit biofilm growth and/or formation. Substances of the present disclosure are products or byproducts of P3-2 (ATCC PTA-6763), P4-4 (ATCC PTA-6682), P5-2 (ATCC PTA-6764), or P6-6 (ATCC PTA-6766) marine bacterial isolates.Type: ApplicationFiled: April 29, 2014Publication date: September 18, 2014Inventor: Cynthia K. Burzell
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Publication number: 20140271497Abstract: A treatment for xerostomia, employing a composition having the active ingredient of safe oral oxygenator and a seed oil is described. The safe oral oxygenator can include either carbamide peroxide or sodium perborate and the seed oil can be macadamia nut oil. The oral care composition may further include one or more additives, such as glycerin (or another humectant), saliva enzyme, proanthocyanidins (e.g., PYCNOGENOL), resveratrol, a sugar alcohol, vitamin B6, vitamin B12, Coenzyme Q10, and folic acid. The oral care composition can be used for the treatment of xerostomia by applying the oral composition to the oral cavity. In addition, this oral care composition can be used for the treatment of vocal cord dysfunction, throat closure, candida, and can be further used in women's intimate care.Type: ApplicationFiled: March 15, 2013Publication date: September 18, 2014Inventor: Susan Morgan
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Patent number: 8834853Abstract: The present invention relates to coated dehydrated microorganisms comprising a dehydrated microorganism surrounded by at least one coating, said coating comprising by dry weight at least 25% of hygroscopic salt(s) and wherein the pH of the coating is compatible with viability of the coated dehydrated microorganism. The coating can be partially crystalline, the salt(s) in the coating having preferably a crystallinity degree of up to 60% once applied onto the dehydrated microorganism. The present invention also relates to liquid coating compositions, methods for coating and protecting a dehydrated microorganism. Finally, the present invention relates to a method for the preparation of food products, feed products, consumer healthcare products or agri-products as well as to a food product, feed product, a consumer healthcare product or an agri-product containing such coated dehydrated microorgansims.Type: GrantFiled: August 13, 2010Date of Patent: September 16, 2014Assignee: DuPont Nutrition Bioscience ApsInventors: Isabelle Mazeaud, Kathryn Tse, Jean-Philippe Obert, Claudette Berger, Geoffrey Babin, Patrick Chaigneau, Hans Hedegaard Jensen, Erwan Henri
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Patent number: 8834850Abstract: The present application relates to the induced remineralization of human tooth enamel and in particular to the building up of apatite on tooth material.Type: GrantFiled: November 11, 2005Date of Patent: September 16, 2014Assignee: Max-Planck-Gesellschaft zur Foerderung der Wissenschaten. e.V.Inventors: Susanne Busch, Rüdiger Kniep
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Publication number: 20140255319Abstract: This invention relates to oral care composition, methods of use and methods of manufacture thereof in the form of a toothtape that can be used to brush or clean teeth and the oral cavity. Particularly, the invention relates to a non-traditional dentifrice that comes in the form of a tape that can, for example, adhere to the oral cavity and particularly the teeth and be dispensed for single use.Type: ApplicationFiled: May 21, 2014Publication date: September 11, 2014Applicant: Colgate-Palmolive CompanyInventors: Sarita V. Mello, Evangelia S. Arvanitidou
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Patent number: 8828454Abstract: The present invention concerns a base characterized in that it is prepared by the following steps: (a) partial bio-hydrolysis of raw materials rich in precursors, and (b) thermal reaction steps of the resulting product from (a). Said base can be prepared with a further step, which is a subsequent or simultaneous fermentation of the resulting product from step (a).Type: GrantFiled: February 18, 2009Date of Patent: September 9, 2014Assignee: Nestec S.A.Inventors: Beatrice Diono, Helge Ulmer, Swen Rabe
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Publication number: 20140234231Abstract: Isolated ?-glucanases from Hypocrea tawa, Trichoderma reesei, and Trichoderma konilangbra are described, as well as oral care compositions containing the same. The oral care composition may be employed to prevent or reduce dental plaque.Type: ApplicationFiled: February 27, 2014Publication date: August 21, 2014Applicant: DANISCO US INC.Inventors: Steven Kim, Suzanne Lantz, Michael Pepsin
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Patent number: 8802059Abstract: An algal extract-based composition for oro-dental use is provided. This composition comprising a mixture of algae with at least Ascophyllum nodosum and Fucus spp. is characterized in that said mixture of algae has a proportion of Ascophyllum nodosum of at least 90% of the weight of the mixture and that the proportion of Fucus spp. is at most 10% of the weight of the mixture, and in that said extract is combined with a natural surfactant and/or with a zeolite or a mixture of zeolites. Uses of said composition, in particular for dental prevention and/or care, are also provided. Applications in the oro-dental field, both preventively and curatively.Type: GrantFiled: December 8, 2011Date of Patent: August 12, 2014Assignee: YS LabInventors: Roxane Fagon, Mélody Dutot, Marc Hemon
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Publication number: 20140186273Abstract: A composition for re-constructing enamel-coated substrates such as a tooth which includes an amelogenin, chitosan, and water. The composition may also include compounds providing calcium and phosphate ions. Methods using the composition are also provided.Type: ApplicationFiled: December 27, 2013Publication date: July 3, 2014Applicant: University of Southern CaliforniaInventors: Janet MORADIAN-OLDAK, Qichao RUAN
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Publication number: 20140178313Abstract: Provided is a novel lactic acid bacterium strain which is capable of suppressing production of volatile sulfur compounds by oral bacteria, has no cariogenicity and no causative role in infective endocarditis, and is safe in an oral cavity, and provided is an agent for preventing, improving and/or treating oral diseases and discomforts by use of the bacterial strain.Type: ApplicationFiled: August 3, 2012Publication date: June 26, 2014Applicant: KABUSHIKI KAISHA YAKULT HONSHAInventors: Takekazu Okumura, Tomohiko Terai, Masumi Nakao, Kimiyuki Kaneko, Masahiko Ito, Kouji Miyazaki, Kazuaki Yamaji, Kaoru Tochiya, Nobuhiro Hanada, Susumu Imai, Yoshiaki Nomura, Shunsuke Baba
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Patent number: 8734807Abstract: Schistosomiasis mansoni is caused by flukes called Schistosoma(es) that enters the human body through the skin in Schistosoma infested waters. The Schistosomes travel from the skin into human blood vessels where they mate, produce antigen containing eggs that travel from the blood vessels into the small intestines, where they are released in the human feces. Male and female Schistosome mates in human blood vessels, male Schistosomes secrete a protein called TGR ? protein to the Trk receptor sites on the females Schistosomes membranes. The process stimulates the formation of chemical SmInAct in female Schistosomes, a chemical necessary for the female Schistosomes to produce eggs. This novel technique describes new methods to inhibit Trk receptor sites on female Schistosome membranes using Trk inhibitor agent to prevent TGR ? proteins from binding to the Trk receptor sites. Thus, preventing SmInAct from being created in female Schistosomes, preventing production of eggs and Schistosomiasis.Type: GrantFiled: April 6, 2013Date of Patent: May 27, 2014Inventor: Gabriel Langlois-Rahme
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Publication number: 20140120041Abstract: Disclosed are oral care compositions, for example dentifrice compositions, comprising an oral care composition comprising an orally acceptable vehicle, metal oxide particles having an average particle size of no greater than a dentin tubule and at least one amino acid capable of chelating the metal oxide. The composition may comprise a polymeric adherent material for adhering the metal oxide particles in the dentin tubule. The metal oxide particles have a median particle size of 5 microns or less, and may comprise zinc oxide.Type: ApplicationFiled: January 6, 2014Publication date: May 1, 2014Applicant: COLGATE-PALMOLIVE COMPANYInventors: Michael Prencipe, Andre Morgan, Venda Porter Maloney
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Patent number: 8709386Abstract: Isolated ?-glucanases from Hypocrea tawa, Trichoderma reesei, and Trichoderma konilangbra are described, as well as oral care compositions containing the same. The oral care composition may be employed to prevent or reduce dental plaque.Type: GrantFiled: April 9, 2009Date of Patent: April 29, 2014Assignee: Danisco US Inc.Inventors: Steven Kim, Suzanne Lantz, Michael Pepsin
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Patent number: 8673324Abstract: The embodiment of invention provides a method for producing ?-aminobutyric acid, including the steps of providing a medium including Saccharomyces cerevisiae, adding an extract of Rhinacanthus nasutus into the medium and fermentating Saccharomyces cerevisiae in the medium added with the extract of Rhinacanthus nasutus to produce ?-aminobutyric acid.Type: GrantFiled: January 19, 2012Date of Patent: March 18, 2014Assignee: Industrial Technology Research InstituteInventors: Ching-Hui Chang, Tsai-Mei Wu
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ORAL CARE COMPOSITION FOR PROMOTING AND MAINTAINING ORAL HEALTH AND METHOD OF FORMING AND USING SAME
Publication number: 20140065078Abstract: An oral care composition, a method of forming the oral care composition, and a method of using the oral care composition are disclosed. The oral care composition includes a plurality of enzymes to prevent formation of and/or facilitate the breakup of biofilm in an oral cavity and a metal ion management system to inhibit growth of gram negative bacteria.Type: ApplicationFiled: September 3, 2013Publication date: March 6, 2014Applicant: Dr. Fresh, LLCInventor: Puneet Nanda -
Patent number: 8642017Abstract: Compositions for a foaming oral cleaner and related methods and products are disclosed. In one such method, a foaming oral cleaner may be dispensed onto a cleaning surface of a tongue cleaning device in a manner to foam the foaming oral cleaner. A surface of the tongue may be brushed using a tongue brush of the tongue cleaning device, thereby applying the foaming oral cleaner to the surface of the tongue. The brushing of the surface of the tongue can dislodge and loosen material on the surface of the tongue. The surface of the tongue can be scraped using a tongue scraper of the tongue cleaning device to scrape dislodged and loosened material from the surface of the tongue. The foaming oral cleaner may be a composition comprising water, a foaming agent, a sweetener, a flavoring agent, an antimicrobial agent comprising a biologically active enzyme, a preservative, and a coloring agent.Type: GrantFiled: January 12, 2012Date of Patent: February 4, 2014Assignee: Orabrush, Inc.Inventor: Robert K. Wagstaff
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Publication number: 20140023597Abstract: The present invention relates to an antimicrobial and immunostimulatory system, applications thereof and a process for the production of the antimicrobial and immunostimulatory system. The present invention provides a storage-stable antimicrobial and immunostimulatory system comprising an oxidoreductase enzyme, a substrate for the oxidoreductase enzyme and hydrogen peroxide in an aqueous solution wherein the substrate for the oxidoreductase enzyme is present up to 90% by weight and water is present up to 20% by weight based on the weight of the total composition; the system has a pH from approximately 4 to 8; and the system provides a two-stage hydrogen peroxide release.Type: ApplicationFiled: December 20, 2012Publication date: January 23, 2014Applicant: INSTITUTE OF TECHNOLOGY SLIGOInventor: INSTITUTE OF TECHNOLOGY SLIGO
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Publication number: 20130344010Abstract: The present invention is concerned with microorganisms or fragments thereof as sensorically neutral oral care agents, particularly for prevention of dental calculus, as anti-caries agents and/or anti-oral malodor agents. The invention is furthermore concerned with compositions comprising microorganisms or fragments thereof for reducing mutans Streptococci. Such compositions can be used in oral care compositions, e.g. for caries prophylaxis, or for prophylaxis of dental calculus or oral malodor. They may also or instead be used for prevention or treatment of oral malodor. As the microorganisms and fragments thereof according to the present invention have a very low, unobtrusive smell and taste, they are particularly suited as sensorically neutral agents for preventment of dental calculus, caries, oral biofilm formation and/or for prevention or treatment of oral malodor.Type: ApplicationFiled: January 12, 2012Publication date: December 26, 2013Applicant: BASF SEInventor: Markus Pompejus
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Publication number: 20130315844Abstract: Described herein are compositions comprising an active compound from an extract of magnolia, or a derivative thereof; and a non-surfactant electrolyte in an amount effective to stabilize the composition, and methods of making and using the same.Type: ApplicationFiled: January 31, 2011Publication date: November 28, 2013Applicant: COLGATE-PALMOLIVE COMPANYInventors: Shyamala Pillai, Lin Fei, Guofeng Xu
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Publication number: 20130302262Abstract: Methods for preventing, reversing, ameliorating or treating dental diseases, disorders or injuries are provided. In particular, methods for preventing, reversing, ameliorating or treating dental diseases of the gingival (gums) and bone are provided. Such methods utilize novel compositions including, but not limited to, extraembryonic cytokine-secreting cells (herein referred to as ECS cells), including, but not limited to, Amnion-derived Multipotent Progenitor cells (herein referred to as AMP cells) and conditioned media derived therefrom (herein referred to as Amnion-derived Cellular Cytokine Solution or ACCS), and Physiologic Cytokine Solution (herein referred to as PCS), each alone or in combination with each other and/or other agents.Type: ApplicationFiled: December 14, 2011Publication date: November 14, 2013Applicant: STEMNION, INC.Inventors: William J Golden, Randall G Rupp
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Publication number: 20130266521Abstract: Oral compositions are provided that comprise a propolis extract; an oral care active compound chosen from: a cationic antibacterial agent, an anti-attachment agent, a biofilm disruption agent, and an anti-inflammatory agent; and a source of fluoride ions. Further, in certain embodiments, the oral composition comprises an anionic polymeric linear polycarboxylate. The oral composition can be in a form of a mouth rinse, a dentifrice, a confectionary, a medicament, or a film. Methods of making and using the oral compositions are also provided.Type: ApplicationFiled: June 3, 2013Publication date: October 10, 2013Inventors: Nataly Fetissova, Claude Blanvalet, Pierre Lambert
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Publication number: 20130266522Abstract: An algal extract-based composition for oro-dental use is provided. This composition comprising a mixture of algae with at least Ascophyllum nodusum and Fucus spp, is characterized in that said mixture of algae has a proportion of Ascophyllum nodusum of at least 90% of the weight of the mixture and that the proportion of Fucus spp. is at most 10% of the weight of the mixture, and in that said extract is combined with a natural surfactant and/or with a zeolite or a mixture of zeolites. Uses of said composition, in particular tot dental prevention and or care are also provided. Applications in the oro-dental field, both preventively and curatively.Type: ApplicationFiled: December 8, 2011Publication date: October 10, 2013Applicant: YS LABInventors: Roxane Fagon, Mélody Dutot, Marc Hemon
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Publication number: 20130251646Abstract: A tooth whitening composition includes an aqueous activation part comprising a peroxide activating component, and a peroxide part comprising a peroxide component that does not contain a peroxide stabilizer, wherein the activation part and the peroxide part are each flowable compositions.Type: ApplicationFiled: March 14, 2013Publication date: September 26, 2013Applicant: GOSMILE, INC.Inventor: Jianxun Feng
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Patent number: 8481005Abstract: Compositions and methods to inhibit adverse physiological effects caused by resin-based and resin-containing materials are disclosed. More specifically, the use of N-acetyl-cysteine (NAC) to inhibit hydroxyethyl methacrylate (HEMA)-mediated cell death and cytotoxicity.Type: GrantFiled: December 22, 2010Date of Patent: July 9, 2013Assignee: The Regents of the University of CaliforniaInventors: Anahid Jewett, Avina Paranjpe
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Publication number: 20130164228Abstract: Described herein are compositions for topical use comprising an antibacterially effective concentration of a gallate or gallamide compound which is a polysubstituted cycloalkyl or heterocycloalkyl wherein the substituents are selected from hydroxy, hydroxymethyl, fluoro, chloro, amino, nitro, or a moiety of formula -X-(CO)-(3,4,5-trihydroxyphenyl), wherein X is selected from O and NH, provided that the substituents comprise at least two moieties of formula -X-(CO)-(3,4,5-trihydroxyphenyl) attached to adjacent carbons in free or in orally or topically acceptable salt form, as well as methods of making and using the same.Type: ApplicationFiled: December 21, 2011Publication date: June 27, 2013Applicant: Colgate-Palmolive CompanyInventors: Stanislav Jaracz, Guofeng Xu, Steven Miller, Leonora Leigh, Guillaume Picquet, Laurence Du-Thumm
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Publication number: 20130121932Abstract: New strains of Lactobacillus that have been selected for their capability of improved reduction the number of Streptococcus mutans in the mouth of mammals through inhibiting activity in combination with better binding to the oral mucins and dental plaque, thereby preventing, reducing or treating dental caries, and products derived from said strains, including agents for treatment or prophylaxis of caries for administration to humans.Type: ApplicationFiled: November 5, 2012Publication date: May 16, 2013Inventors: Bo Mollstam, Eamonn Connolly
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Publication number: 20130028847Abstract: The invention provides a method of preventing, inhibiting or reducing a P. gingivalis biofilm in a subject comprising administering to the subject a pharmaceutical composition comprising an inhibiting agent of a polypeptide that reduces or inhibits biofilm formation and/or biofilm development. Also provided are compositions useful in the prevention, inhibition or treatment of periodontal disease or P. gingivalis infection.Type: ApplicationFiled: July 13, 2012Publication date: January 31, 2013Inventors: Stuart Geoffrey Dashper, Eric Charles Reynolds, Paul David Veith, Ching Seng Ang
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Patent number: 8361445Abstract: The present invention is directed to the use of antibiotics for preparing topical oral antibiotic formulations for treating and/or preventing black-line stains. This invention is further directed to a method of treating and/or preventing black-line stains comprising administration of a topical oral antibiotic formulation. The invention is additionally directed to a topical oral antibiotic formulation for use in treating and/or preventing black-line stains.Type: GrantFiled: January 5, 2011Date of Patent: January 29, 2013Inventor: Ketty Neuner
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Publication number: 20130017238Abstract: Disclosed are oral care compositions, for example dentifrice compositions, comprising an orally acceptable vehicle, metal oxide particles having an average particle size of no greater than a dentin tubule and a polymeric adherent material for adhering the metal oxide particles in the dentin tubule. The metal oxide particles have a median particle size of 5 microns or less, and may comprise zinc oxide.Type: ApplicationFiled: March 31, 2010Publication date: January 17, 2013Applicant: COLGATE-PALMOLIVE COMPANYInventors: Venda Porter, Andre Morgan, Michael Prencipe, Sarita Mello
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Publication number: 20130004565Abstract: Preferred embodiments of the present invention relate to proteolytic enzyme formulations. More specifically, several embodiments relate to a proteolytic formulation to facilitate digestion, metabolism, degradation of target compounds, and systemic enzymatic action. Embodiments for improving oxygenation and reducing plaque are also provided.Type: ApplicationFiled: August 30, 2012Publication date: January 3, 2013Inventor: Jon Barron
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Publication number: 20120328534Abstract: Disclosed herein are compositions and methods to treat an oral cavity surface with a peracid-based benefit agent. The peracid benefit agent can be use for oral surface bleaching, whitening, disinfecting, destaining, deodorizing, decreasing or removing biofilm, and combinations thereof. The peracid is enzymatically generated from a carboxylic acid ester substrate using a CE-7 carbohydrate esterase having perhydrolytic activity (perhydrolase) in the presence of a source of peroxygen. A fusion protein comprising the perhydrolase coupled to a peptidic component having affinity for an oral cavity surface, either directly or through an optional linker, may be used to target the perhydrolytic activity to the oral cavity surface.Type: ApplicationFiled: December 19, 2011Publication date: December 27, 2012Applicant: E. I. DU PONT DE NEMOURS AND COMPANYInventors: Lisa A. Butterick, Scott D. Cunningham, Robert DiCosimo, Kari A. Fosser, Tanja Maria Gruber, Sharon L. Haynie, Mark S. Payne, Pierre E. Rouviere, Hong Wang
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Patent number: 8338153Abstract: A method of producing hexose oxidase by recombinant DNA technology, recombinant hexose oxidase and the use of such enzyme, in particular in the manufacturing of food products such as doughs and dairy products, animal feed, pharmaceuticals, cosmetics, dental care products and in the manufacturing of lactones. Suitable sources of DNA coding for the enzyme are marine algal species including Chondrus crispus, Iridophycus flaccidum and Euthora cristata. In useful embodiments, the recombinant hexose oxidase is produced by Pichia pastoris, Saccharomyces cerevisiae or E. coli.Type: GrantFiled: June 29, 2010Date of Patent: December 25, 2012Assignee: DuPont Nutrition Biosciences APSInventors: Peter Stougaard, Ole Cai Hansen
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Publication number: 20120308491Abstract: Described herein are dentifrice compositions comprising a zinc-containing salt and carboxypeptidase, wherein the zinc-containing salt is not sequestered.Type: ApplicationFiled: January 14, 2011Publication date: December 6, 2012Applicant: COLGATE-PALMOLIVE COMPANYInventors: Ramachandra Shastry, James Masters
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Publication number: 20120308490Abstract: A method of obtaining a preparation of biological origin for oral hygiene to prevent the onset of tooth decay, comprises steps of fermentation of bacteria in a culture medium, separation of the same and purification of the culture medium in which the bacteria have been cultivated, the step of fermentation of bacteria including a combined addition of starch and cellulose to the culture medium to the final concentration in the culture medium between 0.2 g/l and 2 g/l, and preferably of 0.5 g/l each.Type: ApplicationFiled: June 6, 2011Publication date: December 6, 2012Applicant: ABR CONSULTING S.R.L.Inventors: Andrea CARUCCI, Simonetta CASINI
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Publication number: 20120301852Abstract: Described herein, are dental strips comprising a film backing, and an adhesive layer, the adhesive layer comprising a water-swellable polymer and at least one active agent; and uses thereof.Type: ApplicationFiled: January 28, 2011Publication date: November 29, 2012Applicant: Colgate-Palmolive CompanyInventors: Guofeng Xu, David B. Viscio, Abdul Gaffar
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Patent number: 8313749Abstract: A vaccine composition is provided which comprises a rag nucleic acid sequence for the prevention and/or treatment of infection by P. gingivalis. Uses of such nucleic acid sequences, proteins coded for by such sequences and antibodies raised against such proteins in medicine are also provided. Kits for the detection of P. gingivalis in a sample are also provided.Type: GrantFiled: May 19, 2005Date of Patent: November 20, 2012Inventors: Xiaoju Shi, Michael Anthony Curtis
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Publication number: 20120276024Abstract: A comestible, water-based composition containing natural ingredients provides an effective amount of at least one active ingredient selected to reduce the proliferation of bacteria in the mouth of animals to treat and improve the dental health of animals. The composition can be administered to animals in the form of their daily intake of water and may be especially packaged for ready use and consumption by animals in pre-packaged and portable doses. Compositions containing natural ingredients and formulated as toothpastes for animal dental care are also provided.Type: ApplicationFiled: July 10, 2012Publication date: November 1, 2012Applicant: HealthyMouth, LLC.Inventor: Karen Albert
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Publication number: 20120276023Abstract: Biguanide-preserved precipitated calcium carbonate oral care compositions and methods of manufacture thereof are disclosed.Type: ApplicationFiled: December 17, 2010Publication date: November 1, 2012Applicant: COLGATE-PALMOLIVE COMPANYInventors: Nilza Shimohirao, Odete Tieko Yamane, Abel Correia, Katrin Costa, Enzo Utima, Andre S. David
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Publication number: 20120269742Abstract: An orally consumable film composition for delivering breath freshening agents to the oral cavity which is rapidly dissolvable or dispersible in the oral cavity, the composition being comprised of a homogeneous mixture of a water dispersible film forming polymer and an enzyme.Type: ApplicationFiled: June 26, 2012Publication date: October 25, 2012Applicant: COLGATE-PALMOLIVE COMPANYInventors: Lori H. Szeles, Sonya Mohseni, Guofeng Xu, Malcolm Williams, David B. Viscio, James G. Masters
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Publication number: 20120244091Abstract: This invention relates to oral care composition, methods of use and methods of manufacture thereof including a single-tube, non-aqueous dentifrice whitening composition containing at least an enzyme and a substrate.Type: ApplicationFiled: December 4, 2009Publication date: September 27, 2012Inventors: Suman K. Chopra, Lynette Zaidel, Sayed Ibrahim, Leonora Leigh, Michael Prencipe
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Publication number: 20120237454Abstract: The present invention relates to a microorganism belonging to the group of lactic acid bacteria capable of specifically binding to Streptococcus mutans, wherein the specific binding is (i) resistant to heat treatment; (ii) resistant to protease treatment; (iii) calcium-dependent; (iv) formed within a pH range between 4.5 and 8.5; and/or (v) formed in the presence of saliva. The present invention is also relates to an analog or fragment of the microorganism which is thermally inactivated or lyophilized, wherein the analog or fragment retains the capability of specifically binding to Streptococcus mutans. The invention further encompasses compositions and additives for food, feed or drinks comprising the microorganism or an analog or fragment thereof. Also provided is uses of the microorganism or an analog or fragment thereof for the preparation of an anticariogenic or pharmaceutical composition or anticariogenic food or feedstuff as well as methods for producing the compositions or food or feedstuff.Type: ApplicationFiled: May 2, 2012Publication date: September 20, 2012Applicant: BASF AktiengesellschaftInventors: Bruno Kaesler, Rolf Knöll, Mewes Boettner, Eckhard Budde, Christine Lang, Martin Ryser, Markus Veen