Abstract: The invention provides methods and compositions for the detection and/or quantification of a Gram positive bacterial contaminant in a sample. In particular, the invention provides hemocyte-based preparations, methods of making such hemocyte-based preparations, and methods of using such hemocyte-based preparations for the detection and/or quantification of the Gram positive bacterial contaminant.

Abstract: Provided are methods of topical application of an aqueous homeopathic composition for treating various ailments and injuries, including deep tissue wounds and surgical wounds. The aqueous homeopathic composition is formulated in a high potency of at least 400 C, maintained in an aqueous medium and topically applied to a bodily surface for an extended period of time to render therapeutic treatment.

Abstract: A natural pharmaceutical preparation for treating hypoproteinemia, includes at least one member selected from the group consisting of a drug of increasing human serum albium, a drug of improving and enhance immunity, a drug of treating hepatitis B, a drug of treating Hepatitis C, a drug of treating acquired immune deficiency syndrome (AIDS), a drug of treating Tuberculosis, a drug of treat Fibrosis, a drug of treating hydrothorax, a drug of easing pain, a drug of stopping diarrhea, a drug of arresting coughing, a drug of reducing inflammation, and a drug of increasing urine.

Abstract: The novel combinations of flubendiamide and beneficial species comprising flubendiamide and at least one beneficial species from the orders or suborders of the Araneae, Acari, Dermaptera, Hymenoptera, Coleoptera, Neuroptera, Thysanoptera, Heteroptera, Diptera, Hemiptera, Dermaptera and/or Parasitiformes or at least one bacteria strain or at least one virus strain for the effective control of unwanted pests.

Abstract: Disclosed is a composition of matter comprising an OSK1 peptide analog, and in some embodiments, a pharmaceutically acceptable salt thereof. A pharmaceutical composition comprises the composition and a pharmaceutically acceptable carrier. Also disclosed are DNAs encoding the inventive composition of matter, an expression vector comprising the DNA, and host cells comprising the expression vector. Methods of treating an autoimmune disorder and of preventing or mitigating a relapse of a symptom of multiple sclerosis are also disclosed.

Abstract: Disclosed is a composition of matter comprising an OSK1 peptide analog, and in some embodiments, a pharmaceutically acceptable salt thereof. A pharmaceutical composition comprises the composition and a pharmaceutically acceptable carrier. Also disclosed are DNAs encoding the inventive composition of matter, an expression vector comprising the DNA, and host cells comprising the expression vector. Methods of treating an autoimmune disorder and of preventing or mitigating a relapse of a symptom of multiple sclerosis are also disclosed.

Abstract: This invention relates to a pharmaceutical composition and health food comprising herb extracts of one or more herbs selected from the group consisting of Puerariae Radix, Bombycis corpus and Araliae Continentalis Radix. The herb medicine of this invention comprising a single or mixed composition may be useful for the prevention and treatment of renal diseases as well as improvement of renal functions.

Abstract: An antimicrobial composition having the empirical formula of C10H16N6O9.

Abstract: There are provided various compounds and compositions comprising polyunsaturated fatty acid monoglycerides and derivatives thereof. These compounds and compositions can be useful as cancer chemopreventive agents. They can also be useful for enhancing solubility of various active agents and enhancing their bioavailability.

Abstract: A cosmetic composition in solid form includes 25-90% of at least one silicone oil and an extract of Ericerus pela wax. A cosmetic process for caring for and/or making up keratinous matter, includes the application to the keratinous matter of the cosmetic composition. In addition, a process of using an extract of Ericerus pela wax for structuring at least one silicone oil is described.

Abstract: The present invention relates to an aqueous composition for outdoor, indoor, facade and roof paints having a biocidal action.

Abstract: Provided is a formulation containing amorphous or microcrystalline calcium carbonate finely interspersed with organic matter in a ratio of 10 parts of the carbonate per 1 to 3 parts of the organic matter, wherein the organic matter consists of chitin and polypeptide. The formulation is efficient in treating various pathological conditions, including proliferative diseases, neurological disorders, and musculoskeletal disorders.

Abstract: The invention relates to active principles which are capable of inducing the conversion of inactive TGFb-Latent into active TGFb. The invention relates in particular to the use of such an extract for the manufacture of a composition for increasing the concentration of active TGFb1 in the skin, notably in the dermis. The present invention also relates to the uses which are derived from said use, as well as to cosmetic or pharmaceutical compositions which comprise said extract.

Abstract: Methods and compositions for the prevention, therapy and/or treatment of several disease states. The methods comprise the administration of a therapeutically effective amount of a composition including krill extract and conjugated linoleic acid. In addition, the present invention provides new and improved therapeutic compositions including krill extracts and conjugated linoleic acid.

Abstract: The aim of the invention is to extend a range of antiviral drugs by using entovirons in the form of components of an insect hemolymph exhibiting a direct antiviral action. The entovirons obtainable from Odonata, Coleoptera, Lepidoptera and Diptera representatives are most efficient in the form of drug prototypes.

Abstract: The invention relates to obtaining and to the topical use of homogenates, extracts and constituents therefrom (e.g. enzymes, lipids, low-molecular proportions) from pupae of diptera, in particular pupae of flies (e.g., the genera Sarcophaga, Musca, Lucilia, Phormia, Calliphora) for the treatment of open or poorly healing wounds of any origin.

Abstract: A method for controlling the growth of destructive insects and microorganisms in ground soil, includes the step of adding chitin to ground soil for inducing bacteria in the ground soil to synthesize chitinase for controlling the spread of destructive insects and microorganisms therein. The chitin may be added to the ground soil by distributing it on the upper surface of the soil or, preferably, by incorporating into the soil. In a preferred embodiment, the step of deacetylating the carbohydrate chains of the chitin for is carried out before adding to the ground soil for increasing the aqueous solubility of the chitin by producing smaller polymeric units or by increasing the availability of polar hydroxyl groups on glucosyl moieties thereof. Various bacterial cultures may also be added to the chitin prior to its distribution on, or incorporation in, the ground soil.

Abstract: A delivery means for delivering a deliverable material to a wound bed comprises a hydrogel (preferably an optionally cross-linked polyvinylalcohol) and a deliverable material comprising: (i) a decomposable material which in the absence of said hydrogel decomposes and/or is permanently denatured if sterilised using heat, electron beam radiation or gamma radiation; (ii) a protein, protein fragment, peptide or amino acid; or (iii) a secretion or excretion from the organism Lucilia sericata or Drosophila melanogaster.

Abstract: The present invention relates to a novel attractant for fish and mollusks isolated from the eggs of the horseshoe crab, Limulus polyphemus. The invention also relates to a method for attractant peptide extraction, separation, purification, quantitation, and characterization of function. In other aspects, the invention provides for the isolation of the attractant peptide from horseshoe crab eggs for use as “bait” for attracting fish and mollusks. More particularly, the invention relates to the use of biochemical approaches to characterize a peptide attractant, and provides for the creation of recombinant or synthetic attractant peptides, and their use.

Abstract: The present invention relates to a composition for selectively detecting an extremely small amount of peptidoglycan in sample, a preparation method of the composition, and a detection kit for peptidoglycan. It is possible to quantify a small amount of peptidoglycan contained in human blood, tissue, body fluid, water or food, and to diagnose an infection of microorganism with peptidoglycan as a component of cell wall using the composition and the detection kit. In addition, the composition can be applied for a diagnosis reagent of detecting an infection of Gram-positive bacteria in animal or human being in advance, and thus, can be used for the prevention or treatment of food poisonings and bacterial sepsis.

Abstract: Disclosed are methods of producing modified microcrystalline chitosan. Chitosan in aqueous solution is degraded enzymatically, hydrolytically or oxidatively. The chitosan solution is then alkalized with agitation using aqueous hydroxides and/or their salts to attain a pH not lower than 7.0. The precipitated modified microcrystalline chitosan is highly pure and may be concentrated and dried according to known methods. Methods according to the invention also include methods by which an aqueous solution of chitosan is first alkalized using hydroxides and/or their salts to a pH not lower than 7.0. Then the precipitated microcrystalline chitosan is subjected to enzymatic or oxidative degradation to achieve a desired average molecular weight and polydispersity. The product is highly pure and may be concentrated and dried according to known methods.

Abstract: The present invention provides compositions and methods for alleviating physical discomfort and/or pain-related conditions in a subject, comprising one or more ingredients that improve blood circulation, one or more ingredients that reduce pain and one or more ingredients that enhance bone health. The ingredients are selected from synthetic compounds, natural products, natural ingredients, extracts from natural ingredients, or combinations thereof. The compositions of the invention are particularly useful in alleviating musculoskeletal pain and nerve related pain.

Abstract: Pesticidal and/or antimicrobial biological agent-infected hard-bodied arthropod cadavers, such as from the family Tenebrionidae are used to control pest and/or microbial infestations in agriculture, commercial and urban environments.

Abstract: Disclosed is a wound healing composition comprising a mixture of substances that are obtained from diptera larvae, are heat-resistant at 100° C., and have molecular weights ranging from 500 to 10,000 Dalton. Also, disclosed are the use of said composition as well as a method for the production thereof.

Abstract: The present invention provides for methods of preparing purified immune globulins, immune globulin compositions, and methods of treating allergies and conditions by administering immune globulin compositions. For example, the present invention provides for purified IgG4 that is essentially free of other IgG subtypes that can be used to treat allergies and other conditions.

Abstract: The invention provides a cochineal color, a colorant product containing the cochineal color and the method of its production, wherein the cochineal color is free of allergenic proteins and contaminants derived from the raw material Coccus cacti L. insect and can be added with safety to products taken by mouth, such as foods, pharmaceutical products, etc. The invention relates to a cochineal color substantially free of proteins of molecular weight not less than 6000. The invention also relates to a process for producing a cochineal color which comprises subjecting a cochineal extract solution to proteolysis and then to at least one treatment selected from the group consisting of adsorption treatment, ion exchange treatment, acid treatment, extraction treatment and membrane treatment.

Abstract: Present invention relates to a method and composition for symptomatic relief of vaginitis. Until the treatment of underlying cause takes effect women suffer from unpleasant symptoms of vaginitis restricting daily routine activities. The symptoms of vaginitis may be incapacitating and are a common reason for visiting the gynecologist and can lead to frustration, embarrassment, anger, lost days from work, marital conflict and loss of ability to enjoy a normal personal, professional and social life.

Abstract: A process for obtaining a substance with growth promoting activity that includes the step of isolating perivitelline fluid from a fertilized egg of a horseshoe crab. Also, a process for proliferating cells including the steps of isolating perivitelline fluid from a fertilized egg of a horseshoe crab and growing the cells in the presence of the isolated perivitelline fluid.

Abstract: A composition is for feeding aquacultural prey organisms such as Artemia and rotifiers, comprising a lipid component comprising at least 25 wt % of phospholipids and providing a DHA content of at least 30 wt %. The lipid component is preferably derived from marine organisms such as fishmeal, phytoplankton or zoo plankton biomass. The composition is used for providing prey organisms having a high content of highly-unsaturated fatty acids (HUFAs) suitable for aquaculture of fish including halibut, turbot, bass and crustaceans and molluses.

Abstract: The present invention describes pharmaceutically effective substances from the poison of spiders of the family of Sicariidae as well as their preparation and their use in medicine.

Abstract: A pet food product and process for producing the pet food product for use in maintenance of healthy joints and alleviation of arthritic symptoms in companion animals, the pet food comprising an effective amount of an active extract of Perna canaliculus. The extract can be either a powder or lipid extract. Preferably in an amount that provides for a dosage range of generally 0.18 to 114 mg of a powder extract/kg of body weight/day in a companion animal or an amount of generally 1.5 to 1000 mg of a powder extract of Perna canaliculus per 400 kcal of pet food product.

Abstract: An externally applied medicine for treating pediatric hernia utilizes a dosage unit in powder form contained in a fabric pouch which is applied to the navel of a baby suffering from a hernia. The dosage unit is made from four ingredients which are ground to a powder. The ingredients include Salvia chinensis Benth; Rehmannia glutinosa Libosch; Foeniculum vulgare mill; and Cryptotympana postulata faba.

Abstract: For providing an anti-bacteria which is made from a natural material, therefore harmless if it is absorbed in the human body, can be produced in mass production with low cost, and shows a high anti-bacteria effect, the anti-bacteria agent is obtained by heating a shell in an atmosphere of inactive gas and burning the shell under the temperature which finally reaches 700° C.-2,500° C.

Abstract: The present invention relates to a composition for selectively detecting an extremely small amount of peptidoglycan in sample, a preparation method of the composition, and a detection kit for peptidoglycan. It is possible to quantify a small amount of peptidoglycan contained in human blood, tissue, body fluid, water or food, and to diagnose an infection of microorganism with peptidoglycan as a component of cell wall using the composition and the detection kit. In addition, the composition can be applied for a diagnosis reagent of detecting an infection of Gram-positive bacteria in animal or human being in advance, and thus, can be used for the prevention or treatment of food poisonings and Bacterial sepsis.

Abstract: The invention relates to a process for the preparation of extracts from marine ooze. To extract a larger proportion of the cosmetically and balneologically active ingredients from the ooze, the process proposes paraffinum subliquidum, ethanol, dimethicone a water/ethanol mixture and a mixture of water/ethanol/glycerin/propylene glycol. The mixture is extracted while stirring it either for 24 to 30 hours at room temperature or 1 to 3 hours at 50° to 70° C. and is filtered. The filtrate has a proportion of active ingredients from the marine ooze.

Abstract: Isolated nucleic acids encoding an allergen of Dermatophagoides pteronyssinus, Der p III, are disclosed. A cDNA encoding a peptide having a Der p III activity and a predicted molecular weight of about 24,985 daltons is also described. The nucleic acids can be used as probes to detect the presence of Der p III nucleic acid in a sample or for the recombinant production of peptides having an activity of Der p III. Peptides having an activity of Der p III can be used in compositions suitable for pharmaceutical administration or methods of diagnosing sensitivity to house dust mites.

Abstract: Polypeptides of A1-Arg-A2-Cys-Tyr-A3-A4-X-A5-A6-Cit Cys-A7 (I) or their salts (wherein A1 is hydrogen or a residue of arginine, lysine, ornithine, citrulline, alanine, or the like; A2 is an aromatic amino acid residue; A3, A4 and A6 are each a residue of arginine, lysine, ornithine, citrulline, or alanine; A5 is a residue of tyrosine, phenylalanine, alanine, naphthylalanine, or citrulline; A7 is a lysine or arginine residue whose carboxyl group may be converted into amido; and X is a residue of D-ornithyl-proline, prolyl-D-ornithine, D-lysylproline, or the like, with the proviso that any one of A1, A3, A4, A5, A6 and A7 is a residue of alanine or the like or that X is citrulline or the like).

Abstract: A composition and method for facilitating weight loss and aiding in the maintenance of a stable weight in humans, wherein a preferred embodiment of the chemical composition comprises a mixture of psyllium husks generally in an amount of between 72% and 88% by weight of the total chemical composition, natural marine shellfish extract generally in an amount of between 9% and 11% by weight, acacia generally in an amount of between 4.5% and 5.5% by weight, an amount of apple pectin generally in an amount of between 1.4% and 2.2% by weight of the total chemical composition, ascorbic acid (Vitamin C) generally in an amount of between 1.8% and 2.2% by weight. Magnesium stearate may also be included generally in an amount of about 1% by weight of the total chemical composition.

Abstract: The present invention relates to feed additives for crustaceans in aquaculture, in particular crabs. The invention provides methods for making a biological compositions comprising yeast cells that can improve the immune functions of crustaceans in culture. The invention also relates to methods for manufacturing the biological compositions, and methods of using the biological compositions as feed additives.

Abstract: A method for producing a purified Auricularia auricula Polysaccharide (AP) extract of Auricularia auricula (AA). A hydrated predetermined amount of AA is filtered and extracted, producing a first pre-extract. A plurality of additional hydrated predetermined amounts of AA is separately filtered and extracted to produce a plurality of additional pre-extracts. The pre-extracts are combined to form a first extract. The first extract is concentrated and suspended, forming a precipitate. The precipitate is purified to form a first filtrate, and repurified to form a second filtrate. The first and second filtrates are combined to form a first combined filtrate, which is concentrated, purified and dried to form a concentrated extract. The concentrated extract is purified to form a third filtrate, and repurified to form a fourth filtrate.

Abstract: An antiviral agent of an antiviral ability against various viruses and a method of producing the same are provided. A heat treatment is applied to a calcium-containing substance represented by calcium carbonate-containing substances originating from the animal such as clamshell, eggshell, crustacean shell, bone, coral, and pearl, and calcium carbonate-containing minerals such as limestone. When a temperature of the heat treatment is not less than 650° C. and less than a melting point of the calcium component-containing substance, a sufficient time of the heat treatment is 2 to 13 hours.

Abstract: A pet food product and process for producing the pet food product for use in maintenance of healthy joints and alleviation of arthritic symptoms in companion animals, the pet food comprising an effective amount of an active extract of Perna canaliculus. The extract can be either a powder or lipid extract. Preferably in an amount that provides for a dosage range of generally 0.18 to 114 mg of a powder extract/kg of body weight/day in a companion animal or an amount of generally 1.5 to 1000 mg of a powder extract of Perna canaliculus per 400 kcal of pet food product.

Abstract: The invention relates to the topical application of fly larval extracts obtainable from fly larvae which are killed and extracted with cooling in aqueous medium or in solvents and are freed of undissolved constituents. The fly larval extracts of various species are suitable for the treatment of superficial or deep chronic and acute wounds of any etiology. The fly larval extracts with a wound-healing effect are obtainable for example from fly larvae of the genera Sarcophaga or Lucilia.

Abstract: The present invention provides a novel silk-fiber-based matrix having a wire-rope geometry for use in producing a ligament or tendon, particularly an anterior cruciate ligament, ex vivo for implantation into a recipient in need thereof. The invention further provides the novel silk-fiber-based matrix which is seeded with pluripotent cells that proliferate and differentiate on the matrix to form a ligament or tendon ex vivo. Also disclosed is a bioengineered ligament comprising the silk-fiber-based matrix seeded with pluripotent cells that proliferate and differentiate on the matrix to form the ligament or tendon. A method for producing a ligament or tendon ex vivo comprising the novel silk-fiber-based matrix is also disclosed.

Abstract: A stabilized insect mating disruption pheromone compositions comprising an insect pheromone and 2,2′-Methylenebis(6-t-butyl-p-cresol). Methods of use and microcapsules containing these compositions are also provided.

Abstract: Aquarium water and a preparation method thereof, including a fermented solution of a mixture of extract from leaves of a ginkgo tree, extract from ganoderma, extract from bark of a chestnut tree, extract from acorns, extract from leaves of an evergreen oak tree, extract from bamboo, extract from leaves of a persimmon tree, extract from leaves of a pine tree, water-soluble chitosan powder extracted from crab shells, barley natural stone powder, bamboo salt, potato starch, and distilled water. Fermentation is by adding yeast, and organic germanium, mineral component extracted from yellow soil, and extract from combustion of an oak tree are added. The solution is then fermented again and refined in a liquid state.

Abstract: The present invention relates to a natural cell control carrier, more specifically to a natural cell control carrier containing water-soluble chitosan (HFP) and elecampane (Inula Helenium L.) extract, which solves problems of conventional synthesized antibacterial agents and provides various superior properties, improved antibacterial activity and anti-inflammatory effect with a broad antibacterial spectrum, so that it can be used for food, cosmetics and medicine.

Abstract: This invention relates to the identification and characterization of cell proliferating factor in the peri-vatalline fluid of the fertilized eggs of the Indian horseshoe crab.

Abstract: A Chinese medicinal composition useful in preventing and treating cancer comprises:

Abstract: For providing an anti-bacteria which is made from a natural material, therefore harmless if it is absorbed in the human body, can be produced in mass production with low cost, and shows a high anti-bacteria effect, the anti-bacteria agent is obtained by heating a shell in an atmosphere of inactive gas and burning the shell under the temperature which finally reaches 700° C.-2,500° C.