Abstract: Disclosed are applications of a mussel adhesive protein or preparations thereof in suppression of skin inflammations. Specifically disclosed are applications of a mussel adhesive protein, preparations thereof and applications thereof in dermatitis, eczema, skin ulcer, technologies related to burns (comprising skin grafting), perniones, surgical incisions, herpes, abrasions, scars, psoriasis, erythema multiforme, skin damage after radiotherapy, skin cancers, folliculitis, urticaria and drug eruption, and applications in sunburn, polymorphous light eruption, pathological alopecia (comprising hair transplant), acne vulgaris, rosacea (that is, acne rosacea), and the like, and applications in the treatment of otitis externa.

Abstract: The present invention relates to a product obtained from gastropod spawn, to be used to prepare dermatological, cosmetic or cosmeceutical compositions designed for skin care; said product has the capacity to activate and mobilize skin stem cells, as well as prevent the loss thereof that takes place as a consequence of chronological and premature ageing. The present invention also relates to the process followed in order to obtain said product.

Abstract: A therapeutic method for treating diabetes mellitus, particularly diabetes caused by pancreatitis, comprising administering an effective amount of a Chinese herbal medicine to a subject. The Chinese herbal medicine is an extract of a mixture comprising specific amount of raw oyster shell powder, raw Os Draconis, Haematitum (Hematite), Magnetitum (Magnetite), radix Achyranthis Bidentatae (Achyranthes bidentata), rhizoma Dioscoreae (Dioscoreae Rhizoma), radix Paeoniae Rubra (Paeoniae Radix Rubra), radix Rehmanniae (Rehmannia), semen Platycladi (Platycladi Semen), Coptidis Rhizoma, cortex Mori, rhubarb (Rhei Radix et Rhizoma), and Davallia formosana (Davallia formosana Hay.).

Abstract: The present invention relates to a field of veterinary and human medicine. In particular, the invention relates to a composition suitable for parenteral administration, based on hydrolyzate obtained from natural bioresources, a composition for use in treating and/or preventing a pathological condition in a mammal in need thereof, and various other uses thereof. More particularly the invention relates to a composition having immunomodulatory properties being based on a hydrolyzate obtained from bioresources, which composition is used for parenteral administration to a mammal in need thereof.

Abstract: A method for improving skin conditions containing applying a composition containing veratric acid or acceptable salt thereof as an active ingredient. The composition has an excellent effect of reducing skin wrinkles through molecular mechanisms including the promotion of collagen synthesis and inhibition of collagenase activity. Also, the composition has an excellent effect of reducing wrinkles by absorbing UVB to prevent UV rays from penetrating the skin, promotion of collagen synthesis and inhibition of collagenase activity. In addition, the composition has effect of promotion of hair growth and the prevention of hair loss through growth promotion of hair dermal papilla cells, stimulation of IGF-1 secretion, and inhibition of TGF-beta1 secretion. Also, because the composition is derived from plants such as natural materials, it is harmless to the human body and can be safely applied to cosmetic, pharmaceutical, and food compositions.

Abstract: The present invention is related to a pharmaceutical composition comprising snail slime of Helix aspersa müller (Cryptophalus aspersus) (5% to 50%) and marigold extract, propolis and/or almond oil and pharmacologically accepted additives for the prevention additives and/or pharmaceutically acceptable excipients to form a formulation of intermediate to high viscosity (200 to 1000 Pa-s). This invention also relates to the use of a composition which can be formed as a cream or a gel, is preferably soaked in gauze, and shaped as a bandage or sock for the treatment and cure of diabetic foot ulcers and other severe wounds, particularly those associated with diabetes, gout, Lesch Nyhan syndrome or other conditions to the skin, including, keratosis, onychomycosis, ringworm, among others.

Abstract: A white, color-stable, stain-free emulsion formulation containing vanillin for sunless tanning. The amount of vanillin can be adjusted, from about 1% up to about 45%, to provide light or dark tanning of the skin. Lime oil and lime juice form a preferred white emulsion foundation.

Abstract: A white, color-stable, stain-free emulsion formulation containing vanillin for sunless tanning. The amount of vanillin can be adjusted, from about 1% up to about 45%, to provide light or dark tanning of the skin. Lime oil and lime juice form a preferred white emulsion foundation.

Abstract: A Tie2 activator containing, as an active ingredient, a hawthorn extract, a starfruit extract, a shellflower extract, a lotus extract, a rooibos extract, an Indian date extract, a Chinese quince extract, a Psidium guava extract, a long pepper extract, a Quillaja extract, a Kouki extract, a ginkgo extract, an oyster extract, a turmeric extract, a chrysanthemum extract, a jujube extract, a Chinese wolfberry extract, a chamomile extract, or a Butcher's Broom extract, or any combination thereof.

Abstract: The present invention relates to a porous bioceramic composition for bone repair and method of fabrication of the same. 3D-scaffolds were fabricated with a novel micro- and macro-architecture. Porous scaffolds based on dextrin, dextran, gelatin and biomineral (CaCO3) powder were fabricated by heating and freeze-drying methods. Fabrication of different compositions of porous scaffolds (20, 30 wt % of gelatin, 20, 40 wt % dextrin, 30, 40, 50, 60 wt % dextran bounder with the constant quantity of CaCO3 50 g). The scaffolds properties were characterized by x-ray diffraction (XRD), differential scanning calorimetry (DSC), scanning electron microscopy (SEM) and compression tests.

Abstract: Compositions comprising extracts from marine organisms show beneficial effects on skin ailments. Fine lines, wrinkles, and sagging in skin are improved with the application of compositions with marine extracts. Production of collagen, elastin and hyaluronic acid are increased after application of the compositions.

Abstract: This invention provides melanin nanoshells and their use for protection against radiation, particularly ionizing radiation, and electronic pulses, and methods of making materials comprising melanin nanoshells.

Abstract: Beneficial and synergistic effects for alleviating joint pain and symptoms of osteoarthritis and/or rheumatoid arthritis have been found using a mixture of fish oil and fish oil derived, choline based, phospholipid bound fatty acid mixture including polyunsaturated EPA and DHA either alone or in combination with other active constituents, including astaxanthin and polymeric hyaluronic acid or sodium hyaluronate (hyaluronan) in an oral dosage form.

Abstract: To provide a method for producing an oyster meat essence that more amply incorporates an antioxidant substance with high ORAC value as follows. A portion of an oyster meat extract more amply incorporating an antioxidant substance with high ORAC value is selected. An extraction method that allows incorporating further large amount of antioxidant substance with high ORAC value is employed. The beneficial oyster meat extract can be efficiently extracted in large amounts. Object An oyster meat is stored in an extraction container where water is accumulated. An oyster meat essence is extracted to generate an extract liquid. The extract liquid is injected to a centrifuge, and concurrently the centrifuge is rotated at a centrifugal acceleration where an antioxidant substance with high antioxidative potency and ORAC value is separated and removed from the extract liquid. The antioxidant substance with higher antioxidative potency and ORAC value is separated.

Abstract: A method of treating a respiratory disease in an animal comprising the steps of administering to the animal an effective amount of a pharmaceutical composition comprising 1.5 parts by weight powdered fennel, 2.0 parts by weight powdered rhubarb, 1.0 part by weight powdered glycyrrhiza, 2.0 parts by weight powdered phellodendron bark, 1.0 part by weight powdered zedoary, 1.5 parts by weight powdered picrasma wood, 1.0 part by weight powdered matricaria chamomilla, 1.5 parts by weight powdered geranium herb, 1.0 part by weight powdered ginseng, 1.5 parts by weight powdered citrus unshiu peel, 1.0 part by weight powdered scutellaria root, 1.0 part by weight powdered magnolia bark, 2.0 parts by weight powdered oyster shell, 1.0 part by weight powdered cyperus rhizome, 2.0 parts by weight powdered platycodon root, 2.0 parts by weight powdered melia azedarach, 1.0 part by weight powdered cnidium rhizome, 2.0 parts by weight sodium bicarbonate and 4.

Abstract: The present invention is related to a pharmaceutical composition comprising snail slime of Helix aspersa müller (Cryptophalus aspersus) (5% to 50%) and marigold extract, propolis and/or almond oil and pharmacologically accepted additives for the prevention additives and/or pharmaceutically acceptable excipients to form a formulation of intermediate to high viscosity (200 to 1000 Pa-s). This invention also relates to the use of a composition which can be formed as a cream or a gel, is preferably soaked in gauze, and shaped as a bandage or sock for the treatment and cure of diabetic foot ulcers and other severe wounds, particularly those associated with diabetes, gout, Lesch Nyhan syndrome or other conditions to the skin, including, keratosis, onychomycosis, ringworm, among others.

Abstract: Beneficial and synergistic effects for alleviating joint pain and symptoms of osteoarthritis and/or rheumatoid arthritis have been found with krill oil and/or marine oil in combination with other active constituents, including astaxanthin and polymeric hyaluronic acid or sodium hyaluronate (hyaluronan) in an oral dosage form.

Abstract: A Tie2 activator containing, as an active ingredient, a hawthorn extract, a starfruit extract, a shellflower extract, a lotus extract, a rooibos extract, an Indian date extract, a Chinese quince extract, a Psidium guava extract, a long pepper extract, a Quillaja extract, a Kouki extract, a ginkgo extract, an oyster extract, a turmeric extract, a chrysanthemum extract, a jujube extract, a Chinese wolfberry extract, a chamomile extract, or a Butcher's Broom extract, or any combination thereof.

Abstract: The present invention relates to a porous bioceramic composition for bone repair and method of fabrication of the same. 3D-scaffolds were fabricated with a novel micro- and macro-architecture. Porous scaffolds based on dextrin, dextran, gelatin and biomineral (CaCO3) powder were fabricated by heating and freeze-drying methods. Fabrication of different compositions of porous scaffolds (20, 30 wt % of gelatin, 20, 40 wt % dextrin, 30, 40, 50, 60 wt % dextran bounder with the constant quantity of CaCO3 50 g). The scaffolds properties were characterized by x-ray diffraction (XRD), differential scanning calorimetry (DSC), scanning electron microscopy (SEM) and compression tests.

Abstract: Disclosed are articles comprising layered nanocrystalline calcite and methods for forming nanocrystalline calcite layers and compositions comprising nanocrystalline calcite layers.

Abstract: The present invention relates to the field of nutritional support for individuals and reducing the effects of muscle conditions caused by high levels of physical activity. In particular, the invention provides dietary formulations, compositions comprising these formulations and uses of these compositions to support the body's muscle regeneration process.

Abstract: A method of treating a respiratory disease in an animal comprising the steps of administering to the animal an effective amount of a pharmaceutical composition comprising 1.5 parts by weight powdered fennel, 2.0 parts by weight powdered rhubarb, 1.0 part by weight powdered glycyrrhiza, 2.0 parts by weight powdered phellodendron bark, 1.0 part by weight powdered zedoary, 1.5 parts by weight powdered picrasma wood, 1.0 part by weight powdered matricaria chamomilla, 1.5 parts by weight powdered geranium herb, 1.0 part by weight powdered ginseng, 1.5 parts by weight powdered citrus unshiu peel, 1.0 part by weight powdered scutellaria root, 1.0 part by weight powdered magnolia bark, 2.0 parts by weight powdered oyster shell, 1.0 part by weight powdered cyperus rhizome, 2.0 parts by weight powdered platycodon root, 2.0 parts by weight powdered melia azedarach, 1.0 part by weight powdered cnidium rhizome, 2.0 parts by weight sodium bicarbonate and 4.

Abstract: A composition for treating tumors caused by pancreatic, stomach, breast, or liver cancer, leukemia, lung or liver metastasis, and/or arterial aneurysm. The composition comprises in various parts; turtle shell, radix ranunculi ternati, rhizoma dioscoreae bulbiferae, concha arcae, fructus ligustri lucidi, cordyceps sinensis, dwarf lilyturf tuber, Whim brownii, radix astragali, angelica sinensis, radix pseudostellariae, spina date seed, fruit-spike of common selfheal, pericarpium citri reticulatae, costustoot, cape jasmine fruit, radix scrophulariae, radix rehmanniae, rhizoma corydalis, safflower, turmeric root-tuber, cortex moutan, concha ostreae, poria cocos, herba lysimachiae, the root of red-rooted salvia, isatis indigotica fort, honeysuckle, fructus forsythiae, cortex eucommiae, radix gentianae macrophyllae, radix paeoniae alba, subprostrate sophora, seman platycladi, snakegourd fruit, membrane of chicken gizzard, platycodon grandifiorum, and radix liquiritiae.

Abstract: Breast cancer and breast disease are common in women and becoming more frequent in men. Early treatment is vital for better outcomes. This formula consists of a liquid anti-disease topical and/or intraductal anti-breast-disease and anti-cancer—including against precursors to cancer and atypical cells—formula that can be delivered to the source where breast cancer begins by use of a number of bio-available components and multiple diffusion and delivery systems, preventing and/or treating maladies that include, but are not limited to degenerative diseases and accumulation of toxins in the breast tissue. May include homeopathic remedies to be used topically or inside the breast with a delivery method to those regions and may be processed with or without photonic programming or an ionic delivery system for greater effectiveness.

Abstract: In a method of manufacturing a skin care cream containing baked shell powder, highly calcium-containing shells such as dead shells or pearls is baked and crushed to fine powder to obtain baked shell powder. Then, the obtained baked shell powder is added to mix with a raw material for manufacturing cosmetic cream.

Abstract: The present invention relates to nutritional supplement compositions comprising krill meal and lipid insoluble ingredients. The compositions can be used to provide supplementary nutrition to humans or animals. The present invention relates also formulations, such as tablets, which are easy to administer to animals. It is also shown that krill meal added to animal food at low levels will improve the palatability of the product.

Abstract: Compositions are disclosed which have as a component thereof an inhibitor of the enzymatic production of 3-deoxyglucosone (3DG) from fructoselysine and/or an inactivator of 3DG, and which are useful for the treatment or prophylaxis of a condition or disease state that is alleviated by inhibiting such 3DG production. Methods of using such compositions, e.g., for improving the appearance, texture and/or elasticity of aging skin, are also disclosed.

Abstract: Compositions and methods of preparing and using such compositions to treat the symptoms of herpes virus.

Abstract: The invention discloses an eye cream, comprising the following components in part by weight: 2-16 parts of pearl, 0.2-2 parts of borax, 10-28 parts of VE, 0.005-0.05 parts of muscone, 0.2-3 parts of borneol, 30-90 parts of complexe contour des yeux 338Y324 and 0.05-2 parts of zinc carbonate hydroxide. The eye cream has strong moisturizing ability and continuous water lock effect, good abilities of inhibiting melanin and increasing skin lightness, and at the same time has the effects of improving skin texture, i.e. delaying skin aging.

Abstract: The present invention relates to a product obtained from gastropod spawn, to be used to prepare dermatological, cosmetic or cosmeceutical compositions designed for skin care; said product has the capacity to activate and mobilise skin stem cells, as well as prevent the loss thereof that takes place as a consequence of chronological and premature ageing. The present invention also relates to the process followed in order to obtain said product.

Abstract: The present invention relates to a composition for an animal within a particular weight range including at least one non-steroidal anti-inflammatory drug (NSAID) compound and at least one mussel extract characterised in that the therapeutic dose of NSAID compound in the composition is substantially less than the usual therapeutic dose.

Abstract: The present invention relates to a porous bioceramic composition for bone repair and method of fabrication of the same. 3D-scaffolds were fabricated with a novel micro- and macro-architecture. Porous scaffolds based on dextrin, dextran, gelatin and biomineral (CaCO3) powder were fabricated by heating and freeze-drying methods. Fabrication of different compositions of porous scaffolds (20, 30 wt % of gelatin, 20, 40 wt % dextrin, 30, 40, 50, 60 wt % dextran bounder with the constant quantity of CaCO3 50 g). The scaffolds properties were characterised by x-ray diffraction (XRD), differential scanning calorimetry (DSC), scanning electron microscopy (SEM) and compression tests.

Abstract: Provided are compositions comprising Harpagophytum procumens (Devil's claw) root extract and Ribes nigrum (Black Currant) leaf or seed extract. Other components may also be included. Also provided are methods of preventing or treating inflammation or a condition that results from inflammation.

Abstract: Beneficial and synergistic effects for alleviating joint pain and symptoms of osteoarthritis and/or rheumatoid arthritis have been found using a mixture of fish oil and fish oil derived, choline based, phospholipid bound fatty acid mixture including polyunsaturated EPA and DHA wither alone or in combination with other active constituents, including astaxanthin and polymeric hyaluronic acid or sodium hyaluronate (hyaluronan) in an oral dosage form.

Abstract: The present invention provides a proprietary compositions and systems to modulate genetic and metabolomic contributing factors affecting disease diagnosis, stratification, and prognosis, as well as the metabolism, efficacy and/or toxicity associated with specific vitamins, minerals, herbal supplements, homeopathic ingredients, and other ingredients for the purposes of customizing a subject's nutritional supplement formulation to optimize specific health outcomes. Specific to this invention the utilization of certain known polymorphic genes associated with Substance Use Disorder (SUD) are analyzed to target certain genetic anomalies that lead to a high risk and predisposition to SUD. The genotypic patterns are then utilized to provide certain nutritional customized solutions especially related to the attenuation of aberrant abuse of physician prescribed narcotic pain medication across all pain conditions.

Abstract: The present invention provides a dietary supplement that promote the growth, repair, and maintenance of mammalian bone and joint connective tissue. In particular, the dietary supplement comprises a combination of at least one metal chelate and at least one chondroprotective agent.

Abstract: Recombinant fragments of Factor C are disclosed. These proteins and peptides show great potency in recognizing, binding to, neutralizing and removing endotoxin. These molecules can thus be used for anti-microbial, anti-endotoxin, and anti-sepsis therapy. SSCrFCES is a 38 kDa protein representing the LPS-binding domain of Factor C. The ability of SSCrFCES to bind lipid A was analyzed using an ELISA-based assay as well as surface plasmon resonance. Surface plasmon resonance similarly carried out for SSCrFC-sushi-1,2,3-GFP, SSCrFC-sushi-1GFP, and SSCrFC-sushi-3GFP confirmed their superior affinity for endotoxin. The 50% endotoxin-neutralizing concentration of SSCrFCES against 200 EU of endotoxin is 0.069 ?M, suggesting that SSCrFCES is an effective inhibitor of LAL coagulation cascade. Although partially attenuated by human serum, as low as 1 ?M of SSCrFCES inhibits the LPS-induced secretion of hTNF-? and hIL-8 by THP-1 and human pheripheral blood mononuclear cells with a potency more superior than polymyxin B.

Abstract: A method of modulating inflammation in an organism, which includes administering to an organism a composition including a therapeutic amount of an extract from the plant Biota orientatis. Several key components of the extract of Biota orientalis have been identified that have also been shown to have an effect in dramatically reducing inflammatory responses.

Abstract: A natural pharmaceutical preparation for treating hypoproteinemia, includes at least one member selected from the group consisting of a drug of increasing human serum albium, a drug of improving and enhance immunity, a drug of treating hepatitis B, a drug of treating Hepatitis C, a drug of treating acquired immune deficiency syndrome (AIDS), a drug of treating Tuberculosis, a drug of treat Fibrosis, a drug of treating hydrothorax, a drug of easing pain, a drug of stopping diarrhea, a drug of arresting coughing, a drug of reducing inflammation, and a drug of increasing urine.

Abstract: Beneficial and synergistic effects for alleviating joint pain and symptoms of osteoarthritis and/or rheumatoid arthritis have been found with krill oil and/or marine oil in combination with other active constituents, including astaxanthin and polymeric hyaluronic acid or sodium hyaluronate (hyaluronan) in an oral dosage form.

Abstract: The present invention relates to a method for the preparation of mechano-structured nacre by mechanosynthesis of micrometric nacre powder, characterized in that the temperature of the nacre is kept below 40° C. It also relates to the mechano-structured nacre and to uses thereof, in particular on implants and bone substitute pieces on which the mechano-structured nacre is deposited.

Abstract: A method of treatment for cartilage degradation in an organism, which includes administering to an organism a composition including a therapeutic amount of an extract from the plant Biota orientalis. Several key components of the extract of Biota orientalis have been identified that have also been shown to have an effect in dramatically reducing and reversing cartilage degradation.

Abstract: We describe a composition comprising a source of long chain polyunsaturated fatty acid, for example, docosahexaenoic acid (DHA), and a carotenoid, for example, astaxanthin and other nutrients for prophylactic and/or therapeutic use in the healing of trauma- and stress-induced inflammatory conditions.

Abstract: Compositions are disclosed which have as a component thereof an inhibitor of the enzymatic production of 3-deoxyglucosone (3DG) from fructoselysine and/or an inactivator of 3DG, and which are useful for the treatment or prophylaxis of a condition or disease state that is alleviated by inhibiting such 3DG production. Methods of using such compositions, e.g., for improving the appearance, texture and/or elasticity of aging skin, are also disclosed.

Abstract: A method for controlling the growth of destructive insects and microorganisms in ground soil, includes the step of adding chitin to ground soil for inducing bacteria in the ground soil to synthesize chitinase for controlling the spread of destructive insects and microorganisms therein. The chitin may be added to the ground soil by distributing it on the upper surface of the soil or, preferably, by incorporating into the soil. In a preferred embodiment, the step of deacetylating the carbohydrate chains of the chitin for is carried out before adding to the ground soil for increasing the aqueous solubility of the chitin by producing smaller polymeric units or by increasing the availability of polar hydroxyl groups on glucosyl moieties thereof. Various bacterial cultures may also be added to the chitin prior to its distribution on, or incorporation in, the ground soil.

Abstract: The present invention declares a pharmaceutical extract, composition that has effect to treat drug addiction, and its preparation method and quality control method. This extract is extracted from Radix Stephaniae Epigaeae. Starting medicine material of said composition is Radix Ginseng, Radix Astragali, Rhizoma Corydalis, Radix Angelicae Sinensis and Radix Ophiopogonis; and said composition also can prepared by ethanol extract of Radix Ginseng, ethanol extract of Radix Angelicae Sinensis, total alkaloids of Radix Stephaniae Epigaeae, water extract of Radix Astragali and water extract of Radix Ophiopogonis. Quality control method of said pharmaceutical composition includes one of or several of identifications and content determinations. The present invention also declares the use of said pharmaceutical extract, composition in the preparation of a medicine to treat drug addiction.

Abstract: The present invention is related to a method of manufacture of an alkaline mineral bioactive solution of which raw materials are squid bones burnt at a high temperature and crushed powder of red seaweeds and to compositions and health foods having the efficacy for the prevention of osteoporosis. The alkaline aqueous solutions having abundant minerals of the present invention may be used for bioactive solutions having the efficacy for the prevention and improvement of osseous diseases such as osteolysis and osteoporosis in mammals including human beings.

Abstract: The present invention is related to a method of manufacture of an alkaline mineral bioactive solution of which raw materials are squid bones burnt at a high temperature and crushed powder of red seaweeds and to compositions and health foods having the efficacy for the prevention of osteoporosis. The alkaline aqueous solutions having abundant minerals of the present invention may be used for bioactive solutions having the efficacy for the prevention and improvement of osseous diseases such as osteolysis and osteoporosis in mammals including human beings.

Abstract: The present invention provides compositions and methods for alleviating physical discomfort and/or pain-related conditions in a subject, comprising one or more ingredients that improve blood circulation, one or more ingredients that reduce pain and one or more ingredients that enhance bone health. The ingredients are selected from synthetic compounds, natural products, natural ingredients, extracts from natural ingredients, or combinations thereof. The compositions of the invention are particularly useful in alleviating musculoskeletal pain and nerve related pain.

Abstract: A polyherbal preparation for the prevention of atherosclerosis and hyperlipidemia comprising a mixture of Commiphora mukul, Boswellia serrata, Semecarpus anacardium Strychnox nux vomica, Terminalia arjuna and Shankha Bhasma.