Abstract: The present invention relates to physiologically active substances extracted from infected tissues inoculated with a poxvirus. The substances of the present invention have excellent actions to improve blood flow and recover functions of diseased tissues, thus are useful as drugs for various diseases caused by blood flow disorders.
Abstract: An agent for inhibiting proliferation of human malignant tumor cells is obtained by culturing the human malignant tumor cells in a medium and removing the malignant tumor cells from the cultured medium.