Hydrogen Metal Cyanide, Cyanide, Cyanate, Or Thio Analog Thereof Patents (Class 424/607)
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Patent number: 8911790Abstract: The present invention relates to a solid composition including at least one hypothiocyanite (OSCN?) salt combined with a cation, wherein said solid composition is in the form of an amorphous and/or crystalline powder. The invention also relates to a method for producing said solid composition, and to the use thereof.Type: GrantFiled: October 10, 2012Date of Patent: December 16, 2014Assignees: Alaxia SAS, Stragen Pharma SAInventors: Sandrine Perrotto, Sébastien Gluszok, Philippe Bordeau, Catherine David
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Patent number: 8906421Abstract: The present invention provides an aqueous composition and its use for dissolving blood clots in vivo or in clinical or research samples in vitro, said composition comprising at least one chaotropic agent, at least one chelating agent that complexes iron if the chaotropic agent does not complex iron and at least one surface-active emulsifier, the composition being buffered near pH 7.4. The process of dissolving the clot with the aqueous composition is advantageous because it is simple, inexpensive, rapid and can be applied in a variety of contexts, including basic research and clinical situations.Type: GrantFiled: June 21, 2012Date of Patent: December 9, 2014Assignee: MED-Genesis, LLCInventors: John S. Fisher, Fred Ahari, Christopher Jon Perry, Lucjan J. J. Hronowski
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Patent number: 8865225Abstract: A solid composition is provided herein comprising at least one hypothiocyanite salt (OSCN—) of a cation in an amorphous and/or crystalline powder form. Also provided herein are methods of making the composition and methods of treating various conditions, such as airborne infection, lower respiratory tract infection or upper respiratory tract infection.Type: GrantFiled: October 10, 2012Date of Patent: October 21, 2014Assignee: Alaxia SASInventors: Sandrine Perrotto, Sébastien Gluszok, Philippe Bordeau
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Publication number: 20130190178Abstract: The pesticidal compositions comprising synergistic mixtures of O,O-dimethyl S-phthalimidomethyl phosphorodithioate or suitable salt forms thereof, and at least one benzoylurea based chitin inhibiting compound or suitable salt forms thereof, and especially preferably one or more of (RS)-1-[3-chloro-4-(1,1,2-trifluoro-2-trifluoromethoxyethoxy)phenyl]-3-(2,6-di-fluorobenzoyl)urea (also interchangeably referred to as “novaluron”) or suitable salt forms thereof, and 1-(2-chlorobenzoyl)-3-(4-trifluoromethoxyphenyl)urea (also interchangeably referred to as “triflumuron”) or suitable salt forms thereof, for the control of undesired pests, preferably for the control of Codling moths in fruit. Methods of controlling the incidence of undesired pests, via treatment regimens providing synergistic amounts of each of the foregoing compounds, are also disclosed.Type: ApplicationFiled: August 1, 2011Publication date: July 25, 2013Applicant: GOWAN COMERCIO INTEMACIONAL E SERVICOS LIMITADAInventors: Tak Wai Cheung, Gary Louis Melchior, Eric James McEwen, Joszef Selmeczi, Jacques-Laurent Anslaux
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Publication number: 20130089620Abstract: A solid composition is provided herein comprising at least one hypothiocyanite salt (OSCN—) of a cation in an amorphous and/or crystalline powder form. Also provided herein are methods of making the composition and methods of treating various conditions, such as airborne infection, lower respiratory tract infection or upper respiratory tract infection.Type: ApplicationFiled: October 10, 2012Publication date: April 11, 2013Applicant: ALAXIA SASInventor: ALAXIA SAS
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Publication number: 20120328709Abstract: The present invention provides an aqueous composition and its use for dissolving blood clots in vivo or in clinical or research samples in vitro, said composition comprising at least one chaotropic agent, at least one chelating agent that complexes iron if the chaotropic agent does not complex iron and at least one surface-active emulsifier, the composition being buffered near pH 7.4. The process of dissolving the clot with the aqueous composition is advantageous because it is simple, inexpensive, rapid and can be applied in a variety of contexts, including basic research and clinical situations.Type: ApplicationFiled: June 21, 2012Publication date: December 27, 2012Applicant: SYNTHETECH PHARMACEUTICALS, LLCInventors: John S. Fisher, Fred Ahari, Christopher Jon Perry, Lucjan J.J. Hronowski
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Patent number: 8303941Abstract: A composition comprising mineral water and a chelating agent present in an amount sufficient to maintain all of the minerals in the water in solution. The mineral water is preferably obtained from Mount Clemens, Mich., US, and is preferably chelated with an ammonium and/or a sodium salt of an acid selected from the group consisting of ethylenediaminetetraacetic acid, nitrilotetraacetic acid, ?-alaninediacetic acid, ethylenediaminosuccinic acid, aminotrimethylenephosphoric acid, serinediaacetic acid, asparaginediacetic acid, methylgylcinediacetic acid and mixtures thereof. The resultant chelated mineral water may be combined with a cosmetically acceptable skin-conditioning agent and a cosmetically acceptable topical carrier, thereby resulting in a cosmetic composition that will confer beneficial effects on the skin, e.g., softening, hydrating and healing effects.Type: GrantFiled: April 19, 2008Date of Patent: November 6, 2012Assignee: Geologix, Inc.Inventor: Stephen Musumeci
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Patent number: 8278352Abstract: New pesticide compositions comprising an alkyl formate and an isothiocyanic ester are described, as are methods of delivering fumigants and methods of pest control using a combination of fumigants.Type: GrantFiled: May 25, 2005Date of Patent: October 2, 2012Assignee: Commonwealth Scientific & Industrial Research OrganisationInventors: YongLin Ren, Colin Waterford, ByungHo Lee
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Publication number: 20120034313Abstract: A chemical blend that simultaneously kills bacteria and suppresses the production of hydrogen sulfide (H2S) includes both a first chemical, which may be a glutaraldehyde, a tetrakishydroxymethyl phosphonium sulfate (THPS), a quaternary amine compound, a thiocyanate, a carbamate, a cinnamaldehyde, an alkyl dimethyl benzyl ammonium chloride, and/or a diamine diacetate; a second chemical which is a quinone; optionally a third chemical, which is a phosphate compound and a solvent which includes monoethylene glycol. The chemical blend has shown synergistic results for killing bacteria and/or suppressing the production of hydrogen sulfide as compared with the addition of the results of each of the components of the blend used separately.Type: ApplicationFiled: March 15, 2011Publication date: February 9, 2012Applicant: Baker Hughes IncorporatedInventors: Jodi Beth Wrangham, Sebastian D. Mancuso
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Publication number: 20100247673Abstract: In a method of providing anti-sickling of red blood cells in sickle cell anemia patients without hemolyzing the cells comprising, administering in a pharmaceutically acceptable vehicle an anti-sickling, non-hemolyzing amount of thiocyanate selected from the group consisting of alkali metal salts and an ammonium salt until the Hbss relative solubility ratio is at least 1.200 in the deoxygenated hemoglobin-S, the improvement of protecting the thyroid gland in the event of thiocyanate overdose, comprising administering along with the thiocyanate in the pharmaceutically acceptable vehicle, iodine in an amount sufficient to prevent thiocyanate overdose.Type: ApplicationFiled: March 25, 2009Publication date: September 30, 2010Inventor: Oji Agbai
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Publication number: 20100166682Abstract: A composition comprising mineral water and a chelating agent present in an amount sufficient to maintain all of the minerals in the water in solution. The mineral water is preferably obtained from Mount Clemens, Mich., US, and is preferably chelated with an ammonium and/or a sodium salt of an acid selected from the group consisting of ethylenediaminetetraacetic acid, nitrilotetraacetic acid, ?-alaninediacetic acid, ethylenediaminosuccinic acid, aminotrimethylenephosphoric acid, serinediaacetic acid, asparaginediacetic acid, methylgylcinediacetic acid and mixtures thereof. The resultant chelated mineral water may be combined with a cosmetically acceptable skin-conditioning agent and a cosmetically acceptable topical carrier, thereby resulting in a cosmetic composition that will confer beneficial effects on the skin, e.g., softening, hydrating and healing effects.Type: ApplicationFiled: April 19, 2008Publication date: July 1, 2010Applicant: GEOLOGIX, INC.Inventor: Stephen Musumeci
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Patent number: 7045152Abstract: Pulmonary disorders in which the GSNO pool or glutathione pool in the lung is depleted and where reactive oxygen species in lung are increased, are treated by delivering into the lung as a gas, agent causing repletion or increase of the GSNO pool or protection against toxicity and does so independently of reaction with oxygen. Agents include ethyl nitrite, NOCl, NOBr, NOF, NOCN, N2O3, HNO, and H2S. Optionally, N-acetylcysteine, ascorbate, H2S or HNO is administered in addition to other GSNO repleting agent to potentiate the effect of said agent.Type: GrantFiled: February 14, 2001Date of Patent: May 16, 2006Assignee: Duke UniversityInventor: Jonathan S. Stamler
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Patent number: 6866869Abstract: A liquid antimicrobial composition comprises: (1) a mixture of iodide anions and thiocyanate anions; (2) periodic acid or an alkali metal salt thereof; and (3) optionally, a peroxidase. The composition may be used as a microbicide, disinfectant or for suppressing or killing viruses or spores.Type: GrantFiled: January 4, 2002Date of Patent: March 15, 2005Assignee: BASF AktiengesellschaftInventors: Walter Graham Guthrie, Mohammed Shoaib Qureshi, Lawrence Alan Staniforth, Darren Michael Hodgkinson, David Wilson Ashworth
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Publication number: 20040047914Abstract: Sulfuryl fluoride and ovicidal gases have been found to exert a synergistic action on insect eggs, so it is possible to fumigate under sublethal conditions relative to the ovicide, and the dose of ovicidal gas can be reduced e.g. to sublethal concentrations.Type: ApplicationFiled: September 5, 2003Publication date: March 11, 2004Applicant: Solvay Fluor und Derivate GmbHInventors: Klaus Baeumert, Heinz-Joachim Belt
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Patent number: 6001383Abstract: A fumigant, comprising cyanogen (C.sub.2 N.sub.2) provides a viable alternative to conventional fumigants such as methyl bromide, phosphine and carbonyl sulphide. Cyanogen (C.sub.2 N.sub.2) can be used as such a fumigant in the control of a range of biota, including insects, mites, nematodes, fungi and their spores, viruses, spiders, bacteria, molds and rodents. It is also suitable for use on a variety of commodities, including grain, seeds, meats, fruit, vegetables, timber, plants, cut flowers and soil. It is shown that an efficacious concentration of cyanogen (C.sub.2 N.sub.2) as a fumigant leaves a very low residue and can be readily flushed from commodities. In particular, it has been observed that a mixture of (C.sub.2 N.sub.2) and carbon dioxide have a synergistic effect when applied to various biota. The term "cyanogen" is defined as the gas (as STP) cyanogen, (C.sub.2 N.sub.Type: GrantFiled: March 20, 1997Date of Patent: December 14, 1999Assignees: Commonwealth Scientific and Industrial Research Organisation, University of CanberraInventors: Ian G. O'Brien, deceased, Frances James Michael Desmarchelier, Ren Yonglin
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Patent number: 5972987Abstract: A method for removing lice eggs from the hair of an infested human or animal using a nit-visualizing composition. The composition involves the use of certain dyes which have an affinity to the surface of nits, to thereby enable a second individual to more easily see and remove the eggs during a combing or other removal process. To effectuate this purpose, a colored material is dispersed within a water- or alcohol-based solvent and, in one embodiment, a liquefied propellant as well. The composition is applied to the hair of the infested human or animal, and then removed after drying by a process of brushing or washing. However, the colored material which adsorbs to the chitinous exoskeleton and binding cement of the lice eggs remains on the nits, thereby facilitating visual identification and removal of the lice eggs from hair.Type: GrantFiled: March 16, 1999Date of Patent: October 26, 1999Assignee: Lori Fox ReidInventors: Lori Fox Reid, Robert D. Kross
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Patent number: 5503853Abstract: Prophylactic and therapeutic applications of peroxidases for the manufacture of medicaments for the treatment and prevention and treatment of enveloped virus infections and, in particular, of herpes simplex and immunodeficiency virus infections. The medicaments include a peroxidase, a substrate and a peroxide in a pharmaceutically acceptable carrier. Peroxidases of the medicaments include lactoperoxidase and myeloperoxidase. The medicaments are formulated with a pharmaceutically acceptable carrier for topical, oral and injectable administration to individuals in need thereof.Type: GrantFiled: February 19, 1993Date of Patent: April 2, 1996Inventors: Alex Bollen, Nicle Moguilevsky, Michel Pourtois
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Patent number: 5468715Abstract: This invention provides a novel fungicide composition which has bicarbonate-containing inorganic salt ingredients which enhance the efficacy of a fungicide ingredient for the treatment of cultivated crops. The fungicide composition contains nitrogen, phosphorus and potassium fertilizer elements, and the inorganic salt ingredients contain at least two different alkali metal or ammonium cations.Type: GrantFiled: June 2, 1993Date of Patent: November 21, 1995Assignee: Church & Dwight Co., Inc.Inventors: Amy L. Joseph, Keith A. Jones, Anthony E. Winston, M. Stephen Lajoie
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Patent number: 4885363Abstract: Metal-chelating liquids having the formula ##STR1## wherein Y is oxygen or ##STR2## R.sub.Type: GrantFiled: December 23, 1987Date of Patent: December 5, 1989Assignee: E. R. Squibb & Sons, Inc.Inventors: Michael F. Tweedle, Glen T. Gaughan, James T. Hagan