Abstract: The present application relates to aqueous compositions for controlling a plant disease caused by a phytopathogenic organism, to methods of preparing such compositions and to uses of such compositions, for example for controlling a plant disease caused by a phytopathogenic organism. The aqueous compositions comprise copper ions, phosphorous acid and/or a salt thereof and an effective amount of an amine selected from an alkylamine, an alkanolamine and mixtures thereof. The pH of the compositions is from about 6 to about 10.

Abstract: To enhance expression of an antioxidant-related substance in an epidermis by using a diacylglycerol PEG adduct, a method for enhancing expression of an antioxidant-related substance in an epidermis is provided which includes applying a diacylglycerol PEG adduct to the epidermis as an active ingredient. The antioxidant-related substance is an oxidative stress response gene, an antioxidant enzyme, or an antioxidant protein. The diacylglycerol PEG adduct is selected from the group consisting of PEG-12 glycerol dimyristate (GDM12), PEG-12 glycerol distearate (GDS12), PEG-23 glycerol distearate (GDS23), PEG-23 glycerol dipalmitate (GDP23), and PEG-12 glycerol dioleate (GDO12).

Abstract: This document provides methods and materials related to treating rotator cuff conditions (e.g., rotator cuff tendonitis or rotator cuff injuries such as partial rotator cuff tears). For example, methods and materials for using zinc or a zinc chelator to treat rotator cuff conditions are provided.

Abstract: A simple and practical antibacterial treatment with nisin in cracked or uncracked metal tools is provided and easily monitored for its bacteriocin effect.

Abstract: The invention provides compositions for producing hydrogen rich water, nutraceuticals, cosmetics, pharmaceuticals, and other products. In one embodiment, the invention provides a composition, e.g., a tablet, including magnesium metal, at least one water-soluble acid, and a binding agent. The magnesium metal and at least one water-soluble acid may be present in amounts sufficient to maintain a pH of less than 7, e.g., at a specific time period after reaction, and a concentration of at least 0.5 mM H2 after reaction in 50 mL water in a container e.g., a sealed or an open container, e.g., at least 0.5 mM H2 after reaction in 100 mL water or at least 0.5 mM H2 after reaction in 500 mL water. The composition may also include a lubricant.

Abstract: A method of creating nutritional supplements including the steps of obtaining a customer's nutrient deficiency, calculating an ionic supplement composition based on the underlying element composition of the delivery product and the deficiency information, and mixing the ionic elements in dehydrated form with an appropriate liquid suspension.

Abstract: A pressure sensing device is configured for measuring water pressure in a soil medium, and includes a sensor housing and a pressure sensor. The sensor housing is adapted with a sensor cavity delimited by an enveloping surface. The sensor housing is provided with a selective passage for water between an outer surface of the sensor housing and the sensor cavity. The pressure sensor is arranged within the sensor cavity for measurement of a water pressure within the sensor cavity. The pressure sensing device includes an antimicrobial substance for preventing microbial gas production in the sensor cavity.

Abstract: The present technology generally relates to compositions comprising cannabinoids for relieving pain in a subject and to methods of using such compositions for relieving pain in a subject.

Abstract: Embodiments of the present invention pertain to antimicrobial glass compositions, glasses and articles. The articles include a glass, which may include a glass phase and a cuprite phase. In other embodiments, the glasses include as plurality of Cu1+ ions, a degradable phase including B2O3, P2O5 and K2O and a durable phase including SiO2. Other embodiments include glasses having a plurality of Cu1+ ions disposed on the surface of the glass and in the glass network and/or the glass matrix. The article may also include a polymer. The glasses and articles disclosed herein exhibit a 2 log reduction or greater in a concentration of at least one of Staphylococcus aureus, Enterobacter aerogenes, Pseudomonas aeruginosa bacteria, Methicillin Resistant Staphylococcus aureus, and E. coli, under the EPA Test Method for Efficacy of Copper Alloy as a Sanitizer testing conditions and under Modified JIS Z 2801 for Bacteria testing conditions.

Abstract: Embodiments of the present invention pertain to antimicrobial glass compositions, glasses and articles. The articles include a glass, which may include a glass phase and a cuprite phase. In other embodiments, the glasses include as plurality of Cu1+ ions, a degradable phase including B2O3, P2O5 and K2O and a durable phase including SiO2. Other embodiments include glasses having a plurality of Cu1+ ions disposed on the surface of the glass and in the glass network and/or the glass matrix. The article may also include a polymer. The glasses and articles disclosed herein exhibit a 2 log reduction or greater in a concentration of at least one of Staphylococcus aureus, Enterobacter aerogenes, Pseudomomas aeruginosa bacteria, Methicillin Resistant Staphylococcus aureus, and E. coli, under the EPA Test Method for Efficacy of Copper Alloy as a Sanitizer testing conditions and under Modified JIS Z 2801 for Bacteria testing conditions.

Abstract: The present invention relates to the identification of proteins of the WNT signaling pathway as therapeutic targets of pigmentation disorder and as biomarkers of pigmentation status. The invention in particular relates to products and methods for treating a hypopigmentation disorder. The invention also relates to products and methods for detecting, diagnosing, staging or monitoring the course of hypopigmentation disorder and is particularly suited for human subjects.

Abstract: The present invention relates to phytosanitary compositions with fungicidal properties that comprise a mixture of essential oils obtained from plants and agents with known fungicidal properties, such as alkali metal or ammonium bicarbonates, and compounds based on copper or the salts thereof, for use, principally, in contact-protection against fungal infections in cultivated plants and post-harvest, and also in other antifungal applications. In said compositions, the effect of the agents that have known fungicidal properties is potentiated synergistically by the aforementioned essential oils. The present invention also relates to the use of said essential oils as potentiators for agents with known fungicidal properties.

Abstract: Methods for treating cellulosic materials comprising introducing a liquid treating composition into the cellulosic material, the treating composition comprising an aqueous alkaline copper-containing solution comprising copper tetraammine carbonate; and exposing the cellulosic material provided thereby to carbon dioxide to provide treated cellulosic material.

Abstract: This invention provides a method of enhancing plant growth involving the steps of: providing an application of nitrogen-15 isotope to a plant to obtain a concentration of nitrogen-15 isotope at least 10 percent greater than the concentration occurring in an untreated plant. A plant growing in a treated area exhibits at least one of: increased plant yield measured in terms of increased root length and increased leaf area compared to a plant growing in a portion of untreated soil. Furthermore, the step of providing the application of nitrogen-15 isotope to a plant includes treating a foliar portion of a plant with a synergistic concentration of a nitrogen-15 isotope, wherein a treated plant exhibits at least one of: increased plant yield measured in terms of increased root length and increased leaf area, compared to a plant growing without a treatment of a synergistic concentration of the nitrogen-15 isotope.

Abstract: Provided is a composition for improving the nutritional status, reducing the frequency of fever, and/or increasing the immunocompetence of the elderly. The composition is one for improving the nutritional status, reducing the frequency of fever, and/or increasing the immunocompetence of the elderly and comprises the following components (a) to (e): (a) an antioxidant agent; (b) at least one component selected from the group consisting of vitamin B1, vitamin B2, vitamin B6, niacin, and pantothenic acid; (c) at least one component selected from the group consisting of folic acid and vitamin B12; (d) zinc; and (e) selenium.

Abstract: A trace element solution comprises at least the following metals: zinc; manganese; selenium; and copper; and which comprises a concentration of the metals of at least 90 mg/ml. The solution may comprise the following concentrations: at least 60 mg/ml zinc; at least 10 mg/ml manganese; at least 5 mg/ml selenium; and at least 15 mg/ml copper. The solution may comprise chromium, iodine and chromium.

Abstract: Described are methods, uses, and kits for utilizing a targeted ligand conjugate in combination with a thiol inhibitor or a system xc? inhibitor for the treatment of cancer or inflammation. Also described are in vitro assays utilizing a targeted ligand conjugate in combination with a thiol inhibitor or a system xc? inhibitor.

Abstract: A pesticide, fungicidal, bactericidal, anti-pathogen or biocidal composition includes at least one biologically inert carrier; and at least one doped component including at least one fixed copper compound doped with at least one compound selected from the group consisting of iron compounds, zinc compounds, magnesium compounds, calcium compounds, and combinations and/or mixtures thereof. In one embodiment, the doped component has a particle size of about 0.5 nm to about 30 microns. A method for the control of pests includes the step of applying to the pests or their growth habitat the aforementioned composition. The method also includes the control of disease in citrus plants caused by vectors such as Psyllid nymphs, by applying the aforementioned composition to their growth habitat in citrus groves.

Abstract: It is intended to provide an in vitro culture medium that allows the in vitro culture of fertilized eggs to progress normally to the blastocyst stage without arresting the development thereof. The normal development rate of a fertilized egg is improved by using 5-aminolevulinic acids represented by the following formula (I) (wherein R1 represents a hydrogen atom or an acyl group, and R2 represents a hydrogen atom, a linear or branched alkyl group, a cycloalkyl group, an aryl group, or an aralkyl group) or salts thereof as an agent for improving a normal development rate of a fertilized egg.

Abstract: A composition including a hydrate form of magnesium oxide, denoted as MgO.(H2O)n, at a concentration ranging from 1 to 100 weight percent (wt %), where n is any value from 0.1 to 2. The composition may further include MgO at a concentration ranging from 0 to 99 wt %; or Mg(OH)2, at a concentration ranging from 0 to 99 wt %; or Mg(OH)2 at a concentration ranging from 0 to 99 wt %, and MgO, at a concentration ranging from 0 to 99 wt %.

Abstract: The invention relates to a gastroenteric therapeutic composition for oral administration, comprising a compound of monomeric (+)-catechin and at least one basic amino acid, said composition being characterized in that it is used in the form of a complex of (+)-catechin and at least one basic amino acid or at least one derivative or precursor of a basic amino acid for the curative and/or preventive treatment of cancer, said complex having a molar equivalence ratio of the monomeric (+)-catechin to the at least one basic amino acid or the at least one basic amino acid derivative of between 1:1 and 1:2.5.

Abstract: This invention discloses a wood preservative composition for the supplemental or remedial treatment of in-service poles, posts, piling, cross ties and other wooden structures. The wood preservative composition comprises a slow-release micronized copper compound in combination with a boron compound or a fluoride compound.

Abstract: The present invention relates to a composition with trace elements for nutrition. The composition is characterized by an increased content of selenium and/or zinc as a trace element.

Abstract: The present invention relates to a surface treatment and a method for its application for the introduction of a wide variety of differentiating properties to fibersin sliver form through a surface treatment of said fibers. The system can accommodate chemical processes, sonochemical processes, and acoustic cavitation processes whereby the fibers are speckled or plated with at least one predetermined compound in a liquid medium to impart at least one desired property to the fibers and for the orderly inclusion of such treated fibers in sliver form having such properties in yarns, woven, knit, or non-woven textiles.

Abstract: Provided are antibacterial and antimicrobial surface coatings and dental materials by utilizing the antimicrobial properties of copper chalcogenide and/or copper halide (CuQ, where Q=chalcogens including oxygen, or halogens, or nothing). An antimicrobial barrier is created by incorporation of CuQ nanoparticles of an appropriate size and at a concentration necessary and sufficient to create a unique bioelectrical environment. The unique bioelectrical environment results in biocidal effectiveness through a multi-factorial mechanism comprising a combination of the intrinsic quantum flux of copper (Cu0, Cu1+, Cu2+) ions and the high surface-to-volume electron sink facilitated by the nanoparticle. The result is the constant quantum flux of copper which manifests and establishes the antimicrobial environment preventing or inhibiting the growth of bacteria.

Abstract: Bioactive agrichemical concentrates and compositions having improved bioactivity comprising combinations of acid solutions and conventional bioactive agrichemical actives or formulations.

Abstract: A surface-active glass as regenerative anti-fouling material comprising a surface-active glass with a water-soluble glass matrix.

Abstract: The present invention encompasses methods and compositions for detecting pathogenic bacteria. Additionally, the present invention encompasses methods and compositions for catalyzing the dismutation of superoxide radicals.

Abstract: Embodiments of the present disclosure, in one aspect, relate to compositions including a copper/silica nanocomposite and a polymer, methods of making a composition, methods of using a composition, and the like.

Abstract: Bioabsorbable substrates having antimicrobial metal ion coatings that are well suited for implantation in to a subject's body to treat and/or prevent infection. In particular, described herein are flexible bioabsorbable filaments that are coated with an anodic metal (e.g., silver and/or zinc and/or copper) that is co-deposited with a cathodic metal (e.g., palladium, platinum, gold, molybdenum, titanium, iridium, osmium, niobium or rhenium) on the filament so that the anodic metal is galvanically released as antimicrobial ions when the apparatus is inserted into a subject's body. The anodic metal may be at least about 30 percent by volume of the coating.

Abstract: Briefly described, embodiments of this disclosure, among others, include compositions, gels, methods for synthesizing multifunctional silica based nanoparticle gel, method of treating, preventing, or both treating and preventing, a disease in a plant species, method for simultaneously treating citrus plants for citrus canker and preventing the invasion of an Asian Citrus Psyllid (ACP) vector that carries the pathogen and spreads the citrus greening disease in citrus plants, and the like.

Abstract: A copper or copper alloy product is provided, as well as a process for manufacturing a copper or copper alloy product. The product may include copper or copper alloy containing a minimum of 60% copper. The product may include an antimicrobial copper, such as, for example, the antimicrobial copper identified by the United States Environmental Protection Agency (EPA). The product may include, but is not limited to, for example, MD-Cu29™ antimicrobial copper or copper alloy. The antimicrobial copper or copper alloy which contains an antimicrobial touch surface should effectively kill bacteria within about two hours of exposure to the bacteria.

Abstract: Bioactive porous bone graft implants in various forms suitable for use in bone tissue regeneration and/or repair, as well as methods of use are provided. The implants are formed of bioactive glass and have an engineered porosity. The implants may be contained in polymer for enhanced clinical results and better handling.

Abstract: A composition for treating cellulosic materials is provided. The composition comprises a dispersion of micronized additives. The dispersion comprises additive particles with diameters in the range of 0.001 to 25 microns. Also provided is a method for the application of the additive-containing composition to wood, as well as wood products which have been treated with the composition.

Abstract: The invention provides nanodevices or products of manufacture for use as drug delivery vehicles. In one aspect, the invention provides nanodevices or products of manufacture having on-off release mechanisms, e.g., that are “switchable”, or “actuatable” (for example magnetically or ultrasonically switchable), for compounds contained within, e.g., for use as drug delivery nano-vehicles having on-off drug release mechanisms, and their therapeutic applications.

Abstract: The present invention provides a method for preparing a material in the form of liquid for forming an antimicrobial surface coating with multi-level antimicrobial properties, comprising: encapsulating one or more volatile or gaseous biocides in two or more amphiphilic block copolymers to obtain a w/o/w double emulsion, and mixing the w/o/w double emulsion with one or more nonvolatile biocides, each of which is selected from the group consisting of a metal containing biocide, triclosan, a carboxylic acid, a sugar acid and a combination thereof.

Abstract: A metal nanoparticles-doped porous carbon bead having an average size of about 0.4 millimeter (mm) to about 0.6 mm is provided. The metal nanoparticles-doped porous carbon bead is doped with silver, copper, or combinations thereof.

Abstract: Disclosed are a two-agent type disinfectant composition for hard articles, which includes a first agent containing a powder mixture (A) and a second agent containing an aqueous hydrogen peroxide solution (B-1), the powder mixture (A) containing an alkali metal salt (A-1) exhibiting basicity when the salt is in the form of an aqueous solution, a water-soluble copper salt (A-2), a compound (A-3) represented by the following formula (1), and a nonionic surfactant (A-4) represented by the following formula (2), and in which the molar ratio of the water-soluble copper salt (A-2) and the compound (A-3) represented by the mixing amount of (A-3)/mixing amount of (A-2) is 3.

Abstract: The present invention relates to a fluid-permeable primary dressing in strip form, having pores, perforations or honeycomb lattices, which enable the passage of fluid, further having a content of at least one heavy metal present in elemental or ionic form.

Abstract: The disclosure describes collagen constructs comprising antifungal agents, preferably, copper, and related methods.

Abstract: Bioabsorbable substrates having antimicrobial metal ion coatings that are well suited for implantation in to a subject's body to treat and/or prevent infection. In particular, described herein are flexible bioabsorbable filaments that are coated with an anodic metal (e.g., silver and/or zinc and/or copper) that is co-deposited with a cathodic metal (e.g., palladium, platinum, gold, molybdenum, titanium, iridium, osmium, niobium or rhenium) on the filament so that the anodic metal is galvanically released as antimicrobial ions when the apparatus is inserted into a subject's body. The anodic metal may be at least about 30 percent by volume of the coating.

Abstract: This invention provides a composition comprising a biologically effective amount of a compound of Formula 1, an N-oxide or an agriculturally suitable salt thereof wherein R1, R2, R3, R4a, R4b and R5 are as defined in the disclosure, and an effective amount of at least one fungicide.

Abstract: Methods and systems for killing or inhibiting pathogens present in treatments area including but not limited to the nasal cavity, the vaginal area, and the anal area. The methods feature introducing a substrate with an antimicrobial metal into the treatment area. The substrate may be coated, lined, plated, or clad with the antimicrobial metal, either partially or entirely. Or, the substrate itself may be an antimicrobial metal. Antimicrobial metals include but are not limited to copper, zinc, silver, gold, and certain metal alloys. The step of directly contacting the substrate with antimicrobial metal to the treatment area kills or inhibits present pathogens. The antimicrobial metal may leave a trace amount of residue, which may continue to kill or inhibit pathogens after the system has been removed from the treatment area or penetrate into deeper layers of the treatment area.

Abstract: The application discloses the formation of antimicrobial glass-ceramic articles having an amorphous phase and a crystalline phase and an antimicrobial agent selected from the group consisting of silver, copper and a mixture of silver and copper. The antimicrobial glass-ceramic can have a Log Reduction of >2.

Abstract: Systems and methods are described that facilitate generating and storing a concentrated copper and silver ion solution for treating a remote water volume (e.g., a pool, fountain, hot tub, cooling tower, etc.), in accordance with various features described herein. Citric acid and a water-soluble binding polymer are added to a volume of water. The intermediate solution is circulated past an ion generator for a predetermined time period, and copper ions generated thereby are bound by the binding polymer and/or chelated by the citric acid. Once a desired concentration of copper ions has been achieved, the concentrated solution is stored in portable vessels for transport to the remote water volume. Concentrated solution is added to the remote water volume to achieve a concentration therein of approximately 0.2-0.3 ppm.

Abstract: A method of treating or preventing Helicobacter pylori infection in a subject includes the step(s) of: administering to the subject a composition. The composition has a carbonaceous material and an active particle. The active particle is coated on the carbonaceous material and made of a material selected from the group consisting of silver, gold, aluminum, zinc, copper, and titanium dioxide.

Abstract: The invention relates to the stimulation of the synthesis and of the activity of an isoform of lysyl oxidase, and more particularly of the LOXL (lysyl oxidase-like) isoform. The invention relates notably to a method of identifying an active principle which stimulates the formation of elastic fibers. The aim of the invention is mainly to provide such a method of identification so as to provide compositions which enable stimulating the formation of elastic fibers.

Abstract: Active-powder biocidal composition comprising at least one copper salt and at least one zinc salt such that the molar ratio between the copper salt and the zinc salt is within the range of 10 to 1 and each copper and zinc salt, separately, has a solubility constant (Kps) within the range from a value greater than or equal to 1*10-20 to a value less than or equal to 9*10-6. Also included is the biocidal composition that comprises the active-powder composition and a polymer, and the method for the production of said biocidal composition, which comprises: thoroughly mixing the salts in such a manner as to obtain a homogeneous distribution of an active-powder biocidal composition; controlling the mixing temperature such that it remains at approximately less than 50° C.; and mixing the resulting mixture of active powders with a polymer.

Abstract: The present invention relates to the field of food and medicines for the treatment or alleviation of premenstrual syndrome (PMS), premenstrual dysphoric disorder (PMDD), premenopause, menopause and female hormonal disorders. A first embodiment relates to a composition containing vitamins, minerals and oils. Additionally, the invention comprises a pharmaceutical form, more specifically in the form of soft capsules (also known as gelatin) containing the composition of the invention. In particular, the compositions of the invention contain vitamins and minerals in sources compatible with the association of vegetable oils, preferably borage oil, evening primrose oil, or a mixture of two oils, wherein the soft capsule contains a liquid and oily core.

Abstract: Methods of retarding formation of a lipofuscin pigment in the retina and of treating or ameliorating the effects of a disease characterized by an accumulation of a lipofuscin pigment in a retina are provided. These methods include the step of administering to a patient in need thereof a substituted C20-retinoid in an amount sufficient to reduce accumulation of a lipofuscin pigment in the retina. Further provided are methods of retarding formation of A2E and/or ATR-dimer by replacing an all-frans-retinal (ATR) substrate with a C20-D3-retinal substrate under conditions sufficient to impede the formation of A2E. Compositions for retarding formation of a lipofuscin pigment in the retina containing a substituted C20-retinoid and a pharmaceutically acceptable carrier are also provided.