Alkali Or Alkaline Earth Chloride (e.g., Barium Or Lithium Chloride, Etc.) Patents (Class 424/677)
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Patent number: 6387412Abstract: A storage stable magnesium oxychloride coated granular animal feed mineral supplement composition resistant to disintegration cause by moisture absorption and attrition, comprising granular mineral nutrients useful as animal feed supplements and magnesium oxychloride coatings amounting to between 0.5 and 10.0 percent of the weight of the granules, formed on the granules of mineral nutrients by coreaction of magnesium chloride and magnesium oxide. An additional coating of between 0.2 and 2.0 percent magnesium stearate formed on the magnesium oxychloride may be used to decrease the rate of wetting of the granular animal feed mineral supplements.Type: GrantFiled: April 14, 2000Date of Patent: May 14, 2002Assignee: Agri-Nutrients Technology Group, Inc.Inventor: William P. Moore
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Patent number: 6372264Abstract: A method for reducing calcified arterial plaque buildup and cellular malfunction with the administration of therapeutically effective dosages of a compounded coordination complex of magnesium. The method includes steps for making and administering a compounded coordination complex of calcium that balances ionic calcium and does not contribute to unbalanced calcium metabolism, cellular malfunction or calcified arterial plaque buildup. A standardized method for making a compounded coordination complex of inorganic minerals is also disclosed.Type: GrantFiled: August 24, 2000Date of Patent: April 16, 2002Assignee: Gusty Winds CorporationInventor: Michael W. Dixon
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Patent number: 6361800Abstract: This invention is directed to a multi-vitamin and mineral supplement which supplies the right amount of the right micronutrients at the right time to assure adequate intake of micronutrients needed for disease prevention and protection against nutritional losses and deficiencies due to lifestyle factors and common inadequate dietary patterns. The multi-vitamin and mineral supplement is comprised of vitamin A, vitamin C, vitamin D, vitamin E, vitamin K, vitamin B1, vitamin B2, niacinamide, vitamin B6, vitamin B12, biotin, pantothenic acid, iron, phosphorus, iodine, magnesium, zinc, selenium, copper, chromium, potassium, choline, lycopene, and co-enzyme Q-10.Type: GrantFiled: April 13, 2000Date of Patent: March 26, 2002Assignee: Cooper Concepts, Inc.Inventors: Kenneth H. Cooper, Ishwarlal Jialal, Scott Montgomery Grundy, Walter Churchill Willett, Jacob Selhub
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Patent number: 6344482Abstract: The present invention is directed to a method of treating patients with bipolar disorder by administering omega-3 fatty acids.Type: GrantFiled: March 22, 1999Date of Patent: February 5, 2002Inventors: Andrew L. Stoll, Wolfram E. Severus
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Patent number: 6338837Abstract: Compositions for inhibiting nematocyst or polar capsule discharge are provided in the form of an effective amount of antihistamine, an effective amount of antihistamine and an effective amount of at least one cation, or an effective amount of at least one cation. The compositions can be in the form of ointments or can be added to the environment surrounding the nematocysts or polar capsules. Methods of inhibiting nematocyst or polar capsule discharge using the compositions of the invention are also provided.Type: GrantFiled: October 8, 1997Date of Patent: January 15, 2002Assignee: Nidaria Technology Ltd.Inventor: Amit Lotan
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Patent number: 6335308Abstract: A fertilizer composition, prepared by further diluting an aqueous concentrate and containing an admixture prepared from calcium, potassium, iron, boron and humic acid, when applied to sugar-containing plant leaves infested with sugar-eating, slow-moving, soft-bodied insects, decreases the sugar concentration in such leaves sufficiently to discourage such insects and effectively to rid such leaves of those insects.Type: GrantFiled: March 29, 2000Date of Patent: January 1, 2002Inventor: Jerry Kitten
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Patent number: 6309673Abstract: The present invention provides devices and methods for stabilizing bicarbonate-based solutions for peritoneal dialysis or hemofiltration. The bicarbonate-based solutions of the present invention are formulated and stored in at least two parts—an alkaline bicarbonate concentrate and an acidic concentrate. The alkaline bicarbonate concentrate is adjusted to have a pH of about 8.6 to 10.0. The acidic concentrate is adjusted to have a stable, acidic pH ranging from about 1.0 to 3.0. Upon mixing, although some variation in the pH of the mixed bicarbonate solution exists, the inventors have discovered that with the appropriate selection of the parameters of the concentrates, the pH of the mixed solution is always within an acceptable physiological range.Type: GrantFiled: September 10, 1999Date of Patent: October 30, 2001Assignee: Baxter International Inc.Inventors: Annick Duponchelle, Dirk Faict, Patrick Balteau, Jean-Pierre Hartman, Leo Martis, Francesco Peluso
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Patent number: 6291533Abstract: Dietary supplement compositions designed to be responsive to specific blood types, and thus most beneficial for people with specific antigenic blood types.Type: GrantFiled: December 22, 1999Date of Patent: September 18, 2001Assignee: Vitamerica, Inc.Inventor: Albert M. Fleischner
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Patent number: 6277388Abstract: Compositions suitable for cosmetic and/or dermatological use which contain at least one electrolyte and/or at least one primary alcohol, at least one associative polyurethane, at least one oxyalkylenated polymer, and water.Type: GrantFiled: September 24, 1999Date of Patent: August 21, 2001Assignee: L'OrealInventor: Veronique Chevalier
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Publication number: 20010010827Abstract: A method for monitoring ionized Mg2+ concentrations and ionized Ca2+:Mg2+ ratios in a patient, useful in diagnosing and prognosing disease states including headache, cardiopulmonary bypass surgery, hypertension, abnormal pregnancy, head trauma, and fetal abnormalities is provided as well as a composition and a method of treating a patient with ionized Mg2+ or ionized Ca2+ and Mg2+. A method of treating headache is provided.Type: ApplicationFiled: February 7, 2001Publication date: August 2, 2001Inventors: Burton M. Altura, Bella T. Altura, Alexander Mauskop
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Patent number: 6248340Abstract: The present invention generally relates to a composition useful for care of skin conditions and for skin protection and to a method for its preparation. The present invention further relates to a method for skin care and protection using said composition. More specifically, the present invention relates to a composition combining plant and algae extracts with water solutions from the Dead Sea especially useful for treating skin wrinkles and retaining skin moisture, to a method for the preparation thereof and to a method for skin care and protection comprising application of said composition.Type: GrantFiled: January 10, 2000Date of Patent: June 19, 2001Assignee: Dead Sea Laboratories, Ltd.Inventors: Zeev Maor, Shaul Yehuda
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Patent number: 6235317Abstract: An additive for stimulants, useful in particular to reduce the health-damaging effects of coffee beverages, contains one or several vitamins, dandelion root extract, and, if required, one or several mineral salts. The additive characterized in that it contains anise extract and adenosine.Type: GrantFiled: June 16, 1999Date of Patent: May 22, 2001Inventors: György Pintz, Kinga Paczolay
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Patent number: 6218192Abstract: A method of treating headache is provided using a water soluble magnesium salt. Specifically, a method of treating a headache is provided for an individual having a serum ionized magnesium concentration of 0.44 mmoles/L to 0.53 mmoles/L and having at least one headache symptom by administering an amount of a water soluble magnesium salt sufficaent to inhibit at least one headache symptom in the individual within 24 hours and to raise the serum ionized magnesium concentration in the individual to within a normal ionized magnesium concentration range of 0.54 mmoles/L to 0.67 mmoles/L. Headache symptoms which may be inhibited include: pain, aura, photophobia, nausea, unilateral pain and phonophobia.Type: GrantFiled: February 17, 1995Date of Patent: April 17, 2001Assignee: Research Foundation of the State University of New YorkInventors: Burton M. Altura, Bella T. Altura, Alexander Mauskop
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Patent number: 6168809Abstract: The invention relates to the use of an alkaline-earth metal salt in or for the preparation of a cosmetic or pharmaceutical composition, especially for topical application, for treating ocular or palpebral pruritus and/or ocular or palpebral dysesthesia. The cosmetic composition can be used for applying make-up to or removing make-up from sensitive eyes.Type: GrantFiled: April 10, 1996Date of Patent: January 2, 2001Assignee: Societe l'Oreal S.A.Inventors: Olivier De Lacharriere, Lionel Breton
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Patent number: 6132747Abstract: Compositions for inhibiting nematocyst or polar capsule discharge are provided in the form of an effective amount of antihistamine or an effective amount of antihistamine and an effective amount of at least one cation. The compositions can be in the form of ointments or can be added to the environment surrounding the nematocysts or polar capsules. Methods of inhibiting nematocyst or polar capsule discharge using the compositions of the invention are also provided.Type: GrantFiled: May 29, 1997Date of Patent: October 17, 2000Assignee: Nidaria Technology Ltd.Inventor: Amit Lotan
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Patent number: 6110504Abstract: An artificial plasma-like substance having at least one water soluble polysaccharide oncotic agent selected from the group consisting of high molecular weight hydroxyethyl starch, low molecular weight hydroxyethyl starch, dextran 40 and dextran 70, and albumin which is buffered by lactate and has a pre-administration pH of between 5 and 6.5 is disclosed. Also disclosed is an artificial plasma-like solution having at least two water soluble polysaccharide oncotic agents one of which is eliminated from the circulation slowly and the other of which is eliminated from the circulation quickly. Supplimentation of the plasma-like solution with certain ions is described. A system for administration of the plasma-like solution to a subject wherein the system comprises a first and second solution each having particular buffers is described. The plasma-like solution including cryoprotective adducts is also disclosed.Type: GrantFiled: February 17, 1998Date of Patent: August 29, 2000Assignee: Biotime, Inc.Inventors: Paul E. Segall, Harold D. Waitz, Hal Sternberg, Judith M. Segall
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Patent number: 6093423Abstract: A chemical agent for use in binding to and insolubilizing the solubilized products of fat digestion in order to prevent absorption of fat from the diet.Type: GrantFiled: April 25, 1997Date of Patent: July 25, 2000Assignee: Kappa Pharmaceuticals LimitedInventor: Alun Roy Williams
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Patent number: 6066341Abstract: A composition for use in the rehydration and treatment of scours in calves. The composition includes fiber, electrolytes and three energy sources. The energy sources are sugar, medium chain triglycerides and glycine, present in a combined amount of about 14 percent by weight.Type: GrantFiled: March 15, 1999Date of Patent: May 23, 2000Assignee: Farnam Companies, Inc.Inventor: Colleen G. Wilson
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Patent number: 6034091Abstract: Disclosed herein is a method for treating depression associated with alcoholism in a patient comprising administering to the patient a pharmacologically effective dose of an opioid antagonist, and a pharmacologically effective dose of at least one drug compound selected from the group consisting of a tricyclic antidepressant, an a-typical antidepressant, and lithium.Type: GrantFiled: October 2, 1998Date of Patent: March 7, 2000Assignee: John S. NagleInventor: Lee G. Dante
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Patent number: 6034075Abstract: The present invention is directed to a method of treating polycystic ovarian syndrome (PCO) with calcium alone, with vitamin D alone, or with the combination calcium and vitamin D. This invention further provides a method of treating infertility in a woman which comprises administering to the subject an amount of calcium or a derivative thereof effective to treat the infertility. The present invention is also directed to a method of treating irregular menses (oligo/amenorrhea), acne, or hirsutism, insulin resistance, or infertility which comprises administering a combination of calcium or a derivative thereof and vitamin D or a derivative thereof in an amount effective to treat irregular menses (oligo/amenorrhea), acne, or hirsutism, insulin resistance, or infertility.Type: GrantFiled: March 19, 1998Date of Patent: March 7, 2000Assignee: The Trustees of Columbia University in the City of New YorkInventor: Susan Thys-Jacobs
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Patent number: 6020007Abstract: Electrolyte solutions are provided which are useful in electrolyte and fluid therapy, parenteral nutrition and dialysis. The Na:Cl ratio is normalized, plasma and cellular pH are normalized and cellular cofactor ratios are normalized in a manner which decreases toxicity over prior art solutions.Type: GrantFiled: January 11, 1994Date of Patent: February 1, 2000Assignee: BTG International LimitedInventor: Richard L. Veech
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Patent number: 5993863Abstract: The present invention aims at providing an alimentative infusion liquid which has improved stability and preservability and can be administered through a peripheral vein. The infusion liquid contains sugars, amino acids, electrolytes and a fat emulsion at a specific mixing ratio and has a specific pH value and a titratable acidity. The alimentative infusion liquid of the present invention containing the above-described components has good preservability without suffering from precipitation, denaturation and the like problems. Further, since the pH value is adjusted to a specific level and the titratable acidity is retained low, administration of the infusion liquid through a peripheral vein does not cause troubles such as angialiga.Type: GrantFiled: October 7, 1997Date of Patent: November 30, 1999Assignee: Yoshitomi Pharmaceutical Industries, Ltd.Inventors: Masahiro Kikuchi, Yoshihiko Okutani, Tadaaki Inoue, Ryoichiro Murashima, Shunichi Abe, Hiroshi Koshiba, Hiroshi Shibata, Shunichiro Ishii, Yoshiyasu Kawabata, Kazumasa Yokoyama
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Patent number: 5945119Abstract: Various preparations for treating or relieving pain in a patient are disclosed wherein preparations containing caesium ions, preferably in the form of caesium chloride, and preferably also magnesium ions in the form of magnesium sulphate, are administered externally or internally to the patient. In one preferred embodiment a topical preparation is provided which consists of strips of microporous material (A) on each side of a plastics backing layer (B) impregnated with an aqueous solution containing caesium chloride and magnesium sulphate. In an alternative embodiment a cream preparation containing caesium chloride and magnesium sulphate is provided for external application to the patient.Type: GrantFiled: June 6, 1995Date of Patent: August 31, 1999Inventor: John Lai
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Patent number: 5900257Abstract: Cosmetic/dermatological/pharmaceutical compositions, well suited for the treatment of a variety of mammalian disorders of, for example, the skin, hair and/or mucous membranes, a manifestation of which is an excess in the synthesis and/or in the release of substance P, e.g., for the treatment of cutaneous disorders and sensitive skin, comprise an effective substance P antagonist amount of at least one salt of yttrium, lanthanum, cerium, praseodymium, neodymium, promethium, samarium, europium, gadolinium, terbium, dysprosium, holmium, erbium, thulium, ytterbium, lutetium, tin, manganese, or mixture thereof, in a cosmetically/pharmaceutically acceptable medium therefor.Type: GrantFiled: October 28, 1996Date of Patent: May 4, 1999Assignee: Societe L'Oreal S.A.Inventors: Lionel Breton, Olivier De Lacharriere
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Patent number: 5866168Abstract: Dermatological/pharmaceutical compositions, well suited for the therapeutic treatment of and/or alleviation of pain associated with at least one of the skin disorders, zona, poszoster, scald or burns, demodicidosis, skin ulcer, fibrosis, hypertrophic cicatrization and/or acne rosacea, comprise an effective substance P antagonist amount of at least one salt of yttrium, lanthanum, cerium, praseodymium, neodymium, promethium, samarium, europium, gadolinium, terbium, dysprosium, holmium, erbium, thulium, ytterbium, lutetium, tin, zinc, manganese, cobalt, barium, strontium, or mixture thereof, in a dermatologically/pharmaceutically acceptable medium therefor.Type: GrantFiled: October 28, 1996Date of Patent: February 2, 1999Assignee: Societe L'Oreal S.A.Inventors: Olivier De Lacharriere, Lionel Breton
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Patent number: 5851556Abstract: The invention relates to the use of a salt of an alkaline-earth metal in a cosmetic, pharmaceutical, veterinary and/or dermatological composition for treating, in particular, sensitive skins. It relates, in addition, to the use of a salt of an alkaline-earth metal for preventing and/or combating rosacea and/or skin irritation and/or dartre and/or pudic erythema and/or dysesthetic sensation and/or sensation of inflammation and/or pruritus of the skin and/or of the mucous membranes. The salt is in particular strontium nitrate or chloride.Type: GrantFiled: April 10, 1996Date of Patent: December 22, 1998Assignee: Societe L'Oreal S.A.Inventors: Lionel Breton, Olivier De Lacharriere
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Patent number: 5849337Abstract: A method for making and administering a compounded coordination complex of magnesium that enhances the biological absorption of an effective amount of potentiated magnesium, and when administered in therapeutically effective dosages balances calcium metabolism, maintains the homeostasis of the cardiovascular system, and prevents atherosclerosis in the human body.Type: GrantFiled: June 27, 1997Date of Patent: December 15, 1998Assignee: Gusty Winds CorporationInventor: Michael W. Dixon
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Patent number: 5840711Abstract: A composition and a pharmaceutical composition of lithium gamma linolenate and an anti-viral or antibiotic. A method of treating acquired immune deficiency syndrome (AIDS) with lithium gamma linolenate and zidovudine. And a method of decreasing the toxicity of an anti-viral or antibiotic including a step of administering a toxicity reducing effective amount of a composition of a lithium salt with an anti-viral or antibiotic.Type: GrantFiled: January 9, 1997Date of Patent: November 24, 1998Assignee: University of Kentucky Research FoundationInventor: Vincent S. Gallicchio
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Patent number: 5827544Abstract: A method for treatment and prevention of neonatal hyperbilirubinemia by oral administration of a preparation to treat and prevent neonatal hyperbilirubinemia. A preparation that can be used includes castor oil, honey and cellulose fibers. Another preparation that can be used includes castor oil, cellulose fibers, magnesium and vitamin B.sub.2. The magnesium may be in the form of magnesium salts, magnesium oxides or any other form suitable for use in newborns.Type: GrantFiled: October 3, 1996Date of Patent: October 27, 1998Assignee: The Arab Pharmaceutical Manufacturing Co. Ltd.Inventors: Husni H. Abu Seir, Wael F. Sunnoqrot, Bassam M. El-Wadi
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Patent number: 5814347Abstract: A therapeutic composition for the treatment of virus-induced cutaneous infections comprises a first material for blocking viral DNA replication and a second finely divided material which absorbs exudated fluid from vesicles. Preferred compositions comprise a lithium compound (as the material for blocking viral DNA replication) and silica (as the material for absorbing exudated fluid from vesicles). An example of composition in accordance with the invention comprises a lithium compound dissolved or suspended in an aqueous silica salt.Type: GrantFiled: November 6, 1995Date of Patent: September 29, 1998Assignee: Keele UniversityInventor: James Derek Birchall
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Patent number: 5776503Abstract: The present invention provides a dialysis solution that contains amino acids for treating and/or preventing malnutrition in a peritoneal dialysis patient. The amino acid composition is optimized to minimize metabolic acidosis while normalizing amino acid plasma profiles.Type: GrantFiled: July 24, 1997Date of Patent: July 7, 1998Assignee: Baxter International Inc.Inventors: Leo Martis, Michael R. Jones
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Patent number: 5770233Abstract: An object of the present invention is to provide an infusion preparation set (a container filled with infusion liquids) useful for preparation of an infusion liquid containing sugars, amino acids, electrolytes, a fat emulsion and vitamins. The present invention is constituted by the use of a container having two compartments which are separated from each other by a separation means, which contains an infusion liquid comprising a fat emulsion, sugars, fat-soluble vitamins and specified water-soluble vitamins in the first compartment and an infusion liquid comprising amino acids, electrolytes and other specified water-soluble vitamins in the second compartment. An infusion preparation containing sugars, amino acids, electrolytes, a fat emulsion and vitamins can be obtained easily and aseptically upon use, by simply removing a separation means and mixing the infusion liquids included in the first and second compartments.Type: GrantFiled: April 21, 1995Date of Patent: June 23, 1998Assignee: The Green Cross CorporationInventors: Takae Kido, Shigeo Ii, Shun-ichi Abe, Kazumasa Yokoyama
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Patent number: 5756107Abstract: Topical formulations comprising an anti-irritant amount of aqueous-soluble lithium (Li.sup.+) or potassium (K.sup.+) cation, and methods for using the same to inhibit skin irritation, are disclosed.Type: GrantFiled: December 21, 1994Date of Patent: May 26, 1998Assignee: Cosmederm TechnologiesInventors: Gary Scott Hahn, David Orel Thueson
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Patent number: 5747071Abstract: An artificial plasma-like substance having at least one water soluble polysaccharide oncotic agent selected from the group consisting of high molecular weight hydroxyethyl starch, low molecular weight hydroxyethyl starch, dextran 40 and dextran 70, and albumin which is buffered by lactate and has a pre-administration pH of between 5 and 6.5 is disclosed. Also disclosed is an artificial plasma-like solution having at least two water soluble polysaccharide oncotic agents one of which is eliminated from the circulation slowly and the other of which is eliminated from the circulation quickly. Supplimentation of the plasma-like solution with certain ions is described. A system for administration of the plasma-like solution to a subject wherein the system comprises a first and second solution each having particular buffers is described. The plasma-like solution including cryoprotective adducts is also disclosed.Type: GrantFiled: June 5, 1995Date of Patent: May 5, 1998Assignee: BioTime, Inc.Inventors: Paul E. Segall, Harold D. Waitz, Hal Sternberg, Judith M. Segall
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Patent number: 5719119Abstract: Parenteral nutrition aqueous solutions are provided which preferably contain glutamine together with other organic nitrogen containing compounds. The respective concentrations of the compounds present in any given such solution are typically approximately multiples of the concentration of the same compounds as found in normal human plasma, and the respective mole ratios of various such compounds in any given such solution relative to one another are approximately the same mole ratio associated with the same compounds as found in normal human plasma. Processes for using such solutions are provided.Type: GrantFiled: April 26, 1993Date of Patent: February 17, 1998Assignee: British Technology Group, Ltd.Inventor: Richard L. Veech
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Patent number: 5698230Abstract: The present invention provides a dialysis solution that contains amino acids for treating and/or preventing malnutrition in a peritoneal dialysis patient. The amino acid composition is optimized to minimize metabolic acidosis while normalizing amino acid plasma profiles.Type: GrantFiled: March 24, 1997Date of Patent: December 16, 1997Assignee: Baxter International Inc.Inventors: Leo Martis, Michael R. Jones
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Patent number: 5681569Abstract: This invention relates to a composition, preferably in the form of a beverage, whereby cellular hydration and drinkability are enhanced by the combination of green tea solids with selected levels and types of electrolytes and carbohydrates. The compositions comprise (a) from about 0.01% to about 0.35% flavanols; (b) from about 0.01% to about 0.3% sodium ions; (c) from about 0.005% to about 0.08% potassium ions; (d) from about 0.1% to about 20% of a carbohydrate which provides; (i) from about 0.05% to about 10.0% fructose; (ii) from about 0.05% to about 10.0% glucose; and (e) water.Type: GrantFiled: November 6, 1995Date of Patent: October 28, 1997Assignee: The Procter & Gamble CompanyInventors: James Thaddeus Kuznicki, Lana Sandman Turner
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Water-soluble magnesium salts in externally applicable formulations and new combination preparations
Patent number: 5679359Abstract: Water-soluble magnesium salts in preparations for an external application are suitable to weaken UV-induced damages to the skin, especially premature aging of the skin and the formation of skin cancer. The effect is enhanced by a combination with vitamin E and/or vitamin E esters.Type: GrantFiled: January 4, 1996Date of Patent: October 21, 1997Assignee: Wogepharm GmbHInventor: Wolfgang Diezel -
Patent number: 5670176Abstract: The present invention provides a dialysis solution that contains amino acids for treating and/or preventing malnutrition in a peritoneal dialysis patient. The amino acid composition is optimized to minimize metabolic acidosis while normalizing amino acid plasma profiles.Type: GrantFiled: April 4, 1995Date of Patent: September 23, 1997Assignee: Baxter International Inc.Inventors: Leo Martis, Michael R. Jones
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Patent number: 5653973Abstract: Baits useful for controlling lepidoptera populations is made with (a) a diet component for lepidoptera; (b) a toxicant; (c) a chemiluminescent, visual attractant and (d) an encapsulating agent that will allow moisture to permeate and form an external condensate of said diet and said toxicant. The diet, toxicant, and chemiluminescent visual attractant can be used in the same bait particle in a homogeneous or layered structure. Alternatively, the diet/toxicant may be used with a first encapsulating agent in a first bait particle with the chemiluminescent, visual attractant encapsulated in a second bait particle and distributed among the diet/toxicant bait particles.Type: GrantFiled: August 16, 1996Date of Patent: August 5, 1997Assignee: Micro Flo CompanyInventors: Chel W. Lew, Keith Branly, Jesse Gaytan, Osborn Jones Turner
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Patent number: 5585379Abstract: An antiviral topical pharmaceutical composition for treating viral diseases of the skin or mucosa comprises a poorly soluble antiviral nucleoside derivative, dispersed in an aqueous gel carrier containing a gelling agent and a water-soluble carboxylic or dicarboxylic acid salt.Type: GrantFiled: December 28, 1993Date of Patent: December 17, 1996Assignee: AGIS Industries (1983) Ltd.Inventors: Amnon Sintov, Rina Uzan
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Patent number: 5522726Abstract: The present invention is directed to a method for anesthetizing teeth which does not require an injection into the gum in order to anesthetize a tooth (or teeth) which requires attention. The method comprises the step of applying a composition having a high concentration of potassium to a tooth requiring caries removal or manual manipulation thereof. The composition is adapted to anesthetize the tooth so that the tooth may be drilled or manually manipulated. It has been discovered that the potassium enters the dentinal tubules and odontoblastic fibrils and penetrates the pulpal tissues of the tooth for anesthetizing the tooth without having to inject anesthetics into the gum surrounding the tooth.Type: GrantFiled: October 27, 1994Date of Patent: June 4, 1996Inventor: Milton Hodosh
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Patent number: 5505922Abstract: An anesthetic pharmaceutical combination comprising the combination of a local anesthetic and lithium ions present in an amount effective to lower the amount of the local anesthetic necessary to achieve equivalent anesthetic effect in a patient and a method of use of the anesthetic pharmaceutical combination.Type: GrantFiled: February 24, 1995Date of Patent: April 9, 1996Assignee: University of Maryland at BaltimoreInventors: Paul D. Thut, Michael D. Turner
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Patent number: 5464619Abstract: This invention relates to a composition, preferably in the form of a beverage, whereby cellular hydration and drinkability are enhanced by the combination of green tea solids with selected levels and types of electrolytes and carbohydrates. The compositions comprise (a) from about 0.01% to about 0.35% flavanols; (b) from about 0.01% to about 0.3% sodium ions; (c) from about 0.005% to about 0.08% potassium ions; (d) from about 0.1% to about 20% of a carbohydrate which provides; (i) from about 0.05% to about 10.0% fructose; (ii) from about 0.05% to about 10.0% glucose; and (e) water.Type: GrantFiled: June 3, 1994Date of Patent: November 7, 1995Assignee: The Procter & Gamble CompanyInventors: James T. Kuznicki, Lana S. Turner
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Patent number: 5380537Abstract: An irrigating solution used during ocular surgery for endothelium protection and corneal preservation is disclosed. The solution is stored in a single container and mixing prior to use is not required.Type: GrantFiled: November 25, 1992Date of Patent: January 10, 1995Inventor: Guy Andermann
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Patent number: 5326567Abstract: Antimicrobial metal-based compositions, which are photostable, non-staining, and which are easily absorbed into lipophilic matrices, contain silver cations, complexed by acyclic polyether polymers through the formation of a "host-guest relationship" where the acyclic polyether is the "host" and the silver cation is the "guest," wherein stabilization of this "host-guest relationship" is accomplished through the use of excess halide anions. The compositions are useful for topical treatment of infections caused by bacteria, fungus and viruses in humans and animals and for treating medical devices and adhesives to impart infection-resistance.Type: GrantFiled: June 28, 1993Date of Patent: July 5, 1994Inventor: Christopher C. Capelli
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Patent number: 5271947Abstract: A method for reducing the proliferation of dust mites in substrates inhabited by dust mites is accomplished by contacting the substrates such as bedding materials, rugs and upholstered furniture with a sufficient amount of finely divided salt which functions as an acaricide against dust mites, thereby killing the dust mites.Type: GrantFiled: July 24, 1991Date of Patent: December 21, 1993Inventors: Annette Miller, Jeffrey D. Miller
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Patent number: 5262174Abstract: The treatment of viral infections with a lithium salt and one of cytarabine or idoxuridine.Type: GrantFiled: July 18, 1991Date of Patent: November 16, 1993Assignee: Efamol LimitedInventor: David F. Horrobin
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Patent number: 5223271Abstract: The present invention provides a method of treatment and/or prophylaxis of the human or animal body to combat Molluscum Contagiosum, said treatment comprising topically administering a therapeutically or prophylactically effective amount of a physiologically acceptable lithium compound to affected areas on said body.It also extends to pharmaceutical compositions comprising a physiologically acceptable lithium compound together with at least one keratolytic and/or skin penetration assisting agent and at least one pharmaceutically acceptable carrier or excipient.Type: GrantFiled: September 24, 1991Date of Patent: June 29, 1993Assignee: Efamol Holdings PLCInventor: David F. Horrobin
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Patent number: 5160724Abstract: A new barium sulfate contrast medium comprising 20 to 30 w/v % barium sulfate, gum tragacanth and either sodium carboxymethyl cellulose or gum arabic is useful for x-ray examination of the large intestine having adequate radiolucency combined with high coating abilities.Type: GrantFiled: September 19, 1989Date of Patent: November 3, 1992Assignee: Ohta Seiyaku Kabushiki KaishaInventors: Yoshito Tonariya, Yukihito Wada, Kazuhiro Yamaguchi, Tomio Yamazaki, Isamu Sakai, Shigeru Yokoi, Mitsuo Togashi, Yukihiro Noguchi