Abstract: The present invention relates to a solid composition including at least one hypothiocyanite (OSCN?) salt combined with a cation, wherein said solid composition is in the form of an amorphous and/or crystalline powder. The invention also relates to a method for producing said solid composition, and to the use thereof.

Abstract: Methods for treating or preventing radiocontrast agent induced kidney injury in a mammal are disclosed, the methods comprising administering to the mammal a first effective amount of a chalcogenide composition prior to administering a radiocontrast agent to the mammal.

Abstract: The present invention provides methods of reducing the cytotoxic effects of nitric oxide and sulfides comprising coadministering nitric oxide with sulfide. In addition, the present invention provides novel pharmaceutical compositions comprising both nitric oxide and sulfide. The methods and compositions of the present invention may be used in the treatment or prevention of a variety of diseases and disorders, and also in the prevention of cell or tissue damage, including that resulting from ischemia or hypoxia.

Abstract: The present invention relates to methods of treating cancer through stasis induction, wherein said stasis-inducing treatment results in reduced blood flow to the cells of said cancer, leading to diminished tumor growth and/or tumor death. In one embodiment, the stasis-inducing treatment comprises administering a therapeutically effective amount of a chalcogenide, salt, or prodrug thereof. The method of treating cancer may optionally comprise an additional step of withdrawing a portion of blood from said patient, such that blood flow to said cancer is further reduced or eliminated. In additional embodiments, the method of treating cancer may optionally comprise an additional step of diverting a portion of the blood flow in said patient, such that blood flow to said cancer is further reduced or eliminated.

Abstract: The present invention provides an environmentally compatible, pesticidal composition and method for the control of insect pests. The composition includes two components. The first component is a chelating agent, a metal complex of a chelating agent, and mixtures thereof, and the second component is preferably a carrier material.

Abstract: Alterations of redox homeostasis in mammals underlie a host of symptoms, syndromes and diseases, including AIDS and cancer, which can be successfully treated by administration to a mammal of therapeutically-effective amounts of sulfide compounds and/or thiosulfate compounds and/or thionite compounds and/or thionate compounds and/or any chemical species capable of providing to a subject in need thereof a sulfide compound, thiosulfate compound, thionite compound, or thionate compound. The unique compositions of this invention contain one or more “active sulfur substances” in combination with each other or with other therapeutic agents. The invention also encompasses the varying modes of administration of the therapeutic substances. In particular, a novel method of combining active ingredient with wet cellulose is provided, which allows the wet cellulose to function as an enteric carrier.

Abstract: This document discloses molecules having the following formula (“Formula I”):

Abstract: Alterations of redox homeostasis in mammals underlie a host of symptoms, syndromes and diseases, including AIDS and cancer, which can be successfully treated by administration to a mammal of therapeutically-effective amounts of sulfide compounds and/or thiosulfate compounds and/or thionite compounds and/or sulfite compounds and/or thionate compounds and/or any organic, inorganic or organometallic precursors thereof. The unique compositions of this invention contain one or more “active sulfur compounds” in combination with each other or with other therapeutic agents. The invention also encompasses the varying modes of administration of the therapeutic compounds. In particular, a novel method of combining active ingredient with wet cellulose is provided, which allows the wet cellulose to function as an enteric carrier.

Abstract: The present invention provides a composition having an excellent controlling activity on plant disease. The composition comprising the compound represented by the formula (1) and one or more inorganic fungicidal compound selected from the group (A) shows an excellent controlling activity on a plant disease. Group (A): a group consisting of copper oxychloride, basic copper sulphate, copper sulphate, copper hydrochloride, sulfur, and potassium polysulfide.

Abstract: The invention disclosed in this document concerns controlling planthoppers.

Abstract: The present invention provides novel stable, liquid compositions comprising chalcogenides or salts thereof. These compositions may be used for a variety of purposes, including the treatment and prevention of ischemic or hypoxic injury, as well as in the preservation of biological matter.

Abstract: The present invention concerns the use of active compounds, including chalcogenides and sirtuin-modulating compounds, either alone or in combination for increasing or enhancing survivability and/or longevity in biological matter. In general aspects, the chalcogenides and other active compounds may modulate one or more sirtuin proteins. It includes compositions, methods, articles of manufacture and apparatuses for enhancing survivability in any of these biological materials, so as to preserve and/or protect them. In specific embodiments, there are also therapeutic methods and apparatuses for aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, organ transplantation, hyperthermia, wound healing, hemorrhagic shock, cardioplegia for bypass surgery, neurodegeneration, hypothermia, and cancer using the active compounds described.

Abstract: The present invention provides novel stable, liquid compositions comprising chalcogenides or salts thereof. These compositions may be used for a variety of purposes, including the treatment and prevention of ischemic or hypoxic injury, as well as in the preservation of biological matter.

Abstract: The present invention provides novel stable, liquid compositions comprising chalcogenides or salts thereof. These compositions may be used for a variety of purposes, including the treatment and prevention of ischemic or hypoxic injury, as well as in the preservation of biological matter.

Abstract: The present invention provides novel stable, liquid compositions comprising chalcogenides or salts thereof. These compositions may be used for a variety of purposes, including the treatment and prevention of ischemic or hypoxic injury, as well as in the preservation of biological matter.

Abstract: The present invention provides methods of stimulating angiogenesis and the growth or migration of cells associated with angiogenesis, by contacting animals, tissues, or cells with sulfide, alone or in combination with nitric oxide. These methods may be used for a variety of purposes, including promoting wound healing, increasing blood flow, and for the treatment and prevention of diseases and disorders associated with decreased blood flow, including ischemic or hypoxic injury.

Abstract: Methods for treating or preventing radiocontrast agent induced kidney injury in a mammal are disclosed, the methods comprising administering to the mammal a first effective amount of a chalcogenide composition prior to administering a radiocontrast agent to the mammal.

Abstract: The present invention provides methods of reducing the cytotoxic effects of nitric oxide and sulfides comprising coadministering nitric oxide with sulfide. In addition, the present invention provides novel pharmaceutical compositions comprising both nitric oxide and sulfide. The methods and compositions of the present invention may be used in the treatment or prevention of a variety of diseases and disorders, and also in the prevention of cell or tissue damage, including that resulting from ischemi hypoxia.

Abstract: Alterations of redox homeostasis in mammals underlie a host of symptoms, syndromes and diseases, including AIDS and cancer, which can be successfully treated by administration to a mammal of therapeutically-effective amounts of sulfide compounds and/or thiosulfate compounds and/or thionite compounds and/or sulfite compounds and/or thionate compounds and/or any organic, inorganic or organometallic precursors thereof. The unique compositions of this invention contain one or more “active sulfur compounds” in combination with each other or with other therapeutic agents. The invention also encompasses the varying modes of administration of the therapeutic compounds. In particular, a novel method of combining active ingredient with wet cellulose is provided, which allows the wet cellulose to function as an enteric carrier.

Abstract: Topical administration of a generator of H2S in biological tissues for the treatment of eye disorders, such as glaucoma. NaHS caused a time-dependent decrease in intrancular pressure in nomotensive, conscious albino rabbits indicating a similar role for H2S in the regulation of aqueous humor dynamics in animals and humans. H2S donors, NaHS and Na2S, inhibited field-stimulated [3H]NE release from porcine isolated iris-ciliary bodies and produced relaxation of pre-contracted iris muscle strips indicating a pharmacological role for H2S in the anterior uvea. The observation that donors of H2S can alter sympathetic neurotransmission and induce an inhibitory action on iris smooth muscle suggests that this gas has the potential to influence several physiological/pathological processes in the eye. The ability of NaHS or Na2S to inhibit [3H]NE release mimics the well-established action some antiglaucoma drugs (e.g.

Abstract: Alterations of redox homeostasis in mammals underlie a host of symptoms, syndromes and diseases, including AIDS and cancer, which can be successfully treated by administration to a mammal of therapeutically-effective amounts of sulfide compounds and/or thiosulfate compounds and/or thionite compounds and/or sulfite compounds and/or thionate compounds and/or any organic, inorganic or organometallic precursors thereof. The unique compositions of this invention contain one or more “active sulfur compounds” in combination with each other or with other therapeutic agents. The invention also encompasses the varying modes of administration of the therapeutic compounds.

Abstract: A composition for energy-controlled generation and release of at least one gas, which includes an energy-activated catalyst capable of being activated by electromagnetic energy, and a solid or a liquid containing anions capable of being oxidized by the activated catalyst or reacted with species generated during activation of the catalyst to generate at least one gas. The composition, when exposed to electromagnetic energy, is capable of generating and releasing the gas after activation of the catalyst and oxidation or reaction of the anions.

Abstract: A personal care composition is composed of: (a) from about 0.1% to about 99% by weight of a vehicle system which comprises a hydrophobically modified nonionic water soluble polysaccharide polymer which comprises a water soluble polysaccharide polymer backbone and a hydrophobic moiety selected from the group consisting of 3-alkoxy-2-hydroxypropyl group wherein the allyl moiety is a straight or branch chain having 2-6 carbon atoms, C3-C7 alky aryl alkyl, alkyl aryl groups and mixtures thereof, wherein the ratio of the hydrophilic portion to the hydrophobic portion of the polymer is from about 2:1 to 1000:1, and (b) at least one other personal care ingredient. This compostion can be used in a wide range of personal care products such as shampoos, conditioners, hair coloring and styling agents, soaps, body washing agents, underarm products, lubricating agents, oral care products, denture adhesives, sunscreen agents, make-up products, and the like.

Abstract: A method for reducing the production of malodor in sulfur containing dermatological compositions by adjusting the pH of the composition to between about 6.5 to about 8.1. Also, sulfur containing dermatological compositions having a pH between about 6.5 and about 8.1.

Abstract: A mineral supplement or feed for ruminant animals, especially deer, contains effective amounts of sulfur and garlic to repel insects from the animals. By inducing the repellant into the animal via ingestion of the mineral supplement or feed, disease and stress in the animals as caused by the insects is reduced.

Abstract: A bioconjugate including a nanoparticle covalently linked to a biological vector molecule. The nanoparticle is a generally radioactive metal ion and most typically a metal sulfide or metal oxide. The biological vector molecule is typically a monoclonal antibody or fragment of a monoclonal antibody or a peptide having a known affinity to cancer cells. One or more additional, different biological moieties may be covalently linked to the nanoparticle in addition to the biological vector molecule to enhance its activity. The bioconjugate of the present invention has utility as an effective radiopharmaceutical to deliver a radiolabel in tumor treatment.

Abstract: Alterations of redox homeostasis in mammals underlie a host of symptoms, syndromes and diseases, including AIDS and cancer, which can be successfully treated by administration to a mammal of therapeutically-effective amounts of sulfide compounds and/or thiosulfate compounds and/or thionite compounds and/or sulfite compounds and/or thionate compounds and/or any organic, inorganic or organometallic precursors thereof. The unique compositions of this invention contain one or more “active sulfur compounds” in combination with each other or with other therapeutic agents. The invention also encompasses the varying modes of administration of the therapeutic compounds.

Abstract: The invention is characterized by the use in cosmetic compositions of one or more lipophilic derivatives of amino deoxyalditols corresponding to the general formula: in which: R1 is a saturated linear C14-C40 aliphatic radical; R2 is a hydrogen atom or a linear C1-C6 alkyl radical; X is an oxygen atom or a methylene radical; and n is an integer from 1 to 5; with the proviso that when X is a methylene radical R1 contains from 19 to 39 carbon atoms. Application to the preparation of cosmetic compositions for the treatment of keratinous substances and for buccodental hygiene.

Abstract: The gaseous chemical compound, carbonyl sulphide, has hitherto been unknown as a fumigant for the control of insects and mites. Experiments have shown conclusively that carbonyl sulphide can be used as such a fumigant, with fumigation properties comparable to those of phosphine and methyl bromide. The effectiveness of carbonyl sulphide against insects (both adult and immature stages), mites, termites and moulds is demonstrated. In addition, its low absorbtion by grain, lower flammability than phosphine, lack of influence on seed germination, and apparent environmental safety make carbonyl sulphide particularly beneficial as a fumigant of stored grain. It may also be used to fumigate other stored produce (including perishable foodstuff), soil, timber and spaces (such as buildings) and any material likely to be infested by insects or mites, or act as a source of such infestation.

Abstract: The present invention describes a two-part oxidative hair dye composition which comprises in one or both component parts at least one polyether polyurethane in combination with at least one cationic conditioning agent. The two component parts of the composition comprise a dye component composition, which includes primary intermediates and couplers, and a developing component composition, which includes an oxidizing agent, such as hydrogen peroxide. It has surprisingly been found by the present inventors that nonionic polyether polyurethane polymers and cationic conditioning agents contained in the oxidative hair dye compositions of the present invention impart and significantly enhance additional conditioning and rheological benefits to the hair. Other components commonly used in oxidative hair dye products can be added to one or both component parts of the compositions of the present invention.

Abstract: Compositions comprising an aqueous dispersion of lipid vesicles having an aqueous core, wherein the dispersion comprises at least one uncoated pigment dispersed in the aqueous phase and wherein the lipid vesicles with an aqueous core and a lipid membrane formed from at least one fatty acid ester, these compositions being stable, of homogeneous color and containing no or virtually no lumps of pigment, and a process for dispersing a filler in an oil-in-water dispersion of lipid vesicles by means of a high-pressure homogenizer.

Abstract: Hair conditioning compositions comprising 0.1-20% cationic conditioning agent, 0.1-30% fatty alcohol, 0.001-10% nonionic surfactant, 0.001-20% of a polysiloxane having D and T units, wherein the ratio of D units to T units in the polysiloxane is about 10 to 80 D units for every T unit; and 5-95% water; as well as a method for improving the fade resistance of color treated hair comprising applying to the hair an aqueous based hair care composition containing one or more hair treating active ingredients and a siloxane having D and T units, wherein the ratio of D units to T units in the siloxane is about 10 to 80 D units for every T unit.

Abstract: Described herein is a method for making a flake for use in a topical application. The flake is formed by contacting a liquid phase waxy material that may contain pigments, fragrance, plasticizer, hydrophilic modifier with a pseudoplastic hydrophilic gel, and/or an active ingredient. The waxy material contacts the surface of the gel and after the two materials have contacted, the waxy material is solidified and forms a sheet. This sheet is then broken into pieces to form the flakes of the present invention. The flakes can be used in formulating any topical product that can contain a lipid material.

Abstract: There are disclosed stable fluidized polymer suspensions containing cationic polysaccharide, stabilizing agent and emollient. The preferred cationic polysaccharides are cationic guar and cationic hydroxypropyl guar, and preferred emollients are hydrocarbons, silicone oils and esters. Processes for preparing personal care compositions utilizing the fluidized polymer suspensions are also disclosed. Using the fluidized polymer suspensions in the processes provides the advantages of more rapid dissolution and avoidance of lumps and gels when compared to using dry, powdered cationic polysaccharides.

Abstract: Novelty items that are combinations of articles of manufacture with bioluminescence generating systems and/or fluorescent proteins are provided. These novelty items, which are articles of manufacture, are designed for entertainment, recreation and amusement, and include toys, personal items, such as cosmetics, bath powders, body lotions, gels, powders and creams, toothpastes and other dentifrices, soaps, body paints, and bubble bath, fountains, including liquid "fireworks" and other such jets or sprays or aerosols of compositions that are solutions, mixtures, suspensions, powders, pastes, particles or other formulations.

Abstract: Stable, topically applicable oil-in-water bioaffecting emulsions having intermediate viscosity, characteristically ranging from 3 to 10 Pa.multidot.s, comprise (a) from 30% to 50% by weight of at least one pro-penetrating glycol, (b) at least one emulsifying agent, advantageously an anionic amphiphilic polymer, and (c) at least one biologically active agent, for example an active agent that modulates skin differentiation and/or proliferation and/or pigmentation, an anti-inflammatory, an antibacterial, an antifungal, etc.

Abstract: A hair treatment composition for coloring the hair upon the scalp and an eyelash mascara is disclosed. The hair is typically colored with a mascara brush to achieve streaking and a non-homogenous coloring of the hair upon the scalp or the eyelash. A copaiba resin and a metal containing pigment are combined to obtain the hair coloring product. The resultant product is applied to the hair upon the scalp or the eyelash to effect coloring of the hair upon the scalp or the eyelash.

Abstract: A hair treatment composition for temporarily coloring the hair is disclosed. A polymer having repeating units of{--CH.sub.2 (CH.sub.3)C[CO.sub.2 (CH.sub.2).sub.2 N.sup.+ (CH.sub.3).sub.3 X.sup.- ]--}.sub.n ; wherein n has a value of about 25 to 1,000 and X is an anion, and a metal containing pigment are combined. The resultant product is applied to the hair to effect temporary coloring of the hair.

Abstract: Colorant precursors, which are present in the cells of plants belonging to the genus Medicago, such as alfalfa, can react with quinones so as to yield colorants which can be used in dyeing compositions for textiles or hair.

Abstract: The inventions relates to carboxamidopolysiloxanes in cosmetic formulations, especially in skin-, hair-, nail- or mouthcare compositions. The cosmetic state is being improved: wet combability, combing force and static charge.

Abstract: Compositions comprising an aqueous dispersion of lipid vesicles having an aqueous core, wherein the dispersion comprises at least one uncoated pigment dispersed in the aqueous phase and wherein the lipid vesicles with an aqueous core and a lipid membrane formed from at least one fatty acid ester, these compositions being stable, of homogeneous color and containing no or virtually no lumps of pigment, and a process for dispersing a filler in an oil-in-water dispersion of lipid vesicles by means of a high-pressure homogenizer.

Abstract: The present invention provides a method to specifically target hair follicles with formulations which effect the production of hair coloring pigments in the follicle. Liposomal formulations for this purpose are disclosed.

Abstract: Water soluble, cationic products useful as hair colorants or for the treatment of skin which are esters or amides formed by reaction of melanin and a quaternary salt containing a reactive amino or hydroxyl group, as well as compositions containing them and methods of using such products to color hair or treat skin are described.

Abstract: The invention relates to a cosmetic composition containing, in a cosmetically acceptable medium, at least one nonionic surface-active agent from the alkyl polyglycoside class and/or one polyglycerolated nonionic surface-active agent and at least one crosslinked copolymer of maleic anhydride/(C.sub.1 -C.sub.5)alkyl vinyl ether, as well as to a cosmetic treatment process consisting in applying to keratinous matter a cosmetically effective quantity of this composition.

Abstract: A composition for a powdered hair dye includes an oxidative dye component, an oxidizing component and a thickening component. Other additives including protein derivatives and sucrose may also be utilized. The powdered dye composition may be placed into an applicator container so that the container is partially filled with the dye composition. Then when the user desires to use the dye, water is added to the container, the container shaken to mix the water and the powdered dye composition, and the mixture is then applied to the hair using an application mechanism which allows for easy and efficient application of the dye to the hair.

Abstract: Novel 4,4-dihydroxy-5-pyrazolinones having the structural formula (I): ##STR1## and cosmetic/dermatological formulations comprised thereof are useful for artificially coloring, e.g., tanning/browning, human skin and/or hair, and are well suited for imparting a healthy appearance to facial skin by enhancing the radiance of the complexion, while at the same time retaining transparency.

Abstract: The subject of the invention is a cosmetic preparation containing Ilex resin which is isolated from leaves of Ilex aquifolium or Ilex paraguariensis, a method for isolating Ilex resin, and the Ilex resin obtained by this method. Skin treatment preparations containing Ilex resin produce a stable protective film on the skin. Hair treatment preparations containing Ilex resin intensify the color, increase luster, contribute to good wet combability, and improve the elasticity of the hair treated with the preparation.

Abstract: A method of coloring keratinous fibers with, and coloring compositions comprising, a sulfo-containing, water-dispersible polymer having carbonyloxy linking groups, and a colorant reacted into or onto the polymer backbone.

Abstract: Stable sulfide-containing compositions have been developed. The stable sulfide-containing composition comprises a) a sulfide, a polysulfide or mixtures thereof, of an alkali or an alkaline earth metal, and b) a carrier, such that after maintaining the sulfide-containing composition at a temperature of about 37.degree. to about 50.degree. Celsius for about 2 weeks to one month, the sulfide content remaining in the sulfide-containing composition is about 90% or greater of the initial sulfide content. The sulfide-containing compositions can be used for relieving the pain of ingrown toenail by softening the nail, or as a depilatory for removing human hair or hair from animal hides.

Abstract: Water-in-oil-in-water multiple emulsion compositions are disclosed. The multiple emulsion compositions comprise an external aqueous phase optionally incorporating a surfactant system capable of forming liquid crystals as an emulsifier. The internal phase comprises a primary water-in-oil emulsion, wherein the primary emulsion comprises a first topically-active compound, a surfactant phase, an oil phase, and water.