Containing Or Obtained From Valeriana (i.e., Valeriana Officinalis) Patents (Class 424/733)
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Patent number: 6544565Abstract: A method of inhibiting at least one symptomology of Restless Leg Syndrome (RLS) and its related disorders, including disorders such as periodic limb movements in sleep (PLMS) and periodic limb movement disorder (PLMD), is disclosed. The method optionally comprising identifying a host, afflicted with Restless Leg Syndrome (RLS) and its related disorders; and administering to the host a pharmaceutically effective amount of Valeriana. A novel method of inhibiting at least one symptomology of Restless Leg Syndrome (RLS) and its related disorders is disclosed.Type: GrantFiled: November 28, 2001Date of Patent: April 8, 2003Assignee: Ancile Pharmaceuticals, Inc.Inventors: Keith Hoffman, Costas Loullis
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Publication number: 20030054051Abstract: This invention relates to a composition for inducing smoking cessation comprising as active ingredient alkaloids from Radix ipecauanhae. In smoking cessation program using the composition, the considerable number of volunteers participated in the program became nausea and thus ultimately to have no craving for smoking.Type: ApplicationFiled: September 13, 2001Publication date: March 20, 2003Inventors: Hwa-Mok Park, Byung-Zun Ahn
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Publication number: 20030054049Abstract: The object of the invention is to provide perfumes that is effective on physiologically manifested stresses and the perfume compositions comprising the same that is effective on stress reduction. The invention provides the stress relieving perfumes wherein the active component is valerian oil, especially fatty acid-removed valerian oil, and stress relieving perfume compositions containing the same.Type: ApplicationFiled: February 13, 2002Publication date: March 20, 2003Inventors: Ken Shoji, Keiko Sakai
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Publication number: 20030017220Abstract: A process for preparing a pharmaceutically-active extract of the root of a plant of the family Valerianacae, specifically, Valeriana officinalis L., is described. This process comprises the steps of adding the roots to an alcoholic extraction solvent to form a mixture, wherein the alcoholic extraction solvent comprises between approximately 50% to approximately 100% (v/v) in a remainder of water, and heating the mixture to a temperature of between approximately 70° C. to approximately 80° C. for a period of at least approximately two hours. By this process valerenic acid is obtained in the extract, and the extract has a content of valepotriates and valepotriate degradation products or derivatives that is substantially reduced with respect to the content of valepotriates in the roots, and has a content of valerenic acids that is not substantially reduced with respect to the content of valerenic acids in the roots.Type: ApplicationFiled: April 11, 2002Publication date: January 23, 2003Inventors: Michael J. Andrews, Amaresh Basu
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Publication number: 20020192283Abstract: A coating for masking or reducing the detectable presence of certain characteristic odor or odors, taste or tastes of pharmaceutical preparations, particularly Valerian extracts, is described. The coating comprises from one to three coating compartments, in any combination or as a single-layer amalgam. The first coating compartment comprises a hydroxyalkyl cellulose and an anti-tackiness agent. The second coating compartment may comprise a sugar and at least one anti-tackiness agent. The third coating compartment may comprise a methacrylate copolymer, a hydroxyalkyl cellulose and an anti-tackiness agent.Type: ApplicationFiled: May 14, 2002Publication date: December 19, 2002Inventors: I-Lan T. Sue, Pou-Hsiung Wang
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Patent number: 6495172Abstract: A method of using steam ironing of fabrics as a way of causing reduction of physiological and/or subjective reactivity to stress in a human is provided. The method includes the steps of providing a stress reducing composition comprising one or more of a volatile natural essential oil and water. The composition is adapted to not cause staining of fabrics. The method includes delivering the stress reducing composition into a liquid container of a steam iron and heating the steam iron. The method further includes releasing vapors of the stress reducing composition produced within the liquid container of the steam iron upon heating into ambient air. The method still further includes the step of causing reduction of physiological and/or subjective reactivity to stress in the human by one of more of transdermal ingestion or inhalation of the vapors by the human.Type: GrantFiled: June 15, 2001Date of Patent: December 17, 2002Assignee: Procter & GambleInventors: Paul Amaat France, Arseni V. Radomyselski
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Patent number: 6458384Abstract: A first pharmacologically active substance contained in a pharmaceutical, which acts on a specific biological function, is released according to a predetermined release profile (D.1), FIG. 1, and generates a first activity profile (I.1) that has flank phases with increasing and decreasing activity intensity. For changing such flank phases, an additional pharmacologically active substance is used which acts on the same biological function and which is released according to a release profile (D.2) such that its activity profile (I.2) overlays the first activity profile (I.1) within the flank phase to be changed. For shortening an end flank phase, an additional substance is used whose activity is counter to the activity of the first substance and cancels, reduces, or overpowers this activity in its declining phase. Accordingly, with the aforementioned pharmaceutical, undesirable aftereffects of a pharmacologically active substance, for example, can be prevented.Type: GrantFiled: February 23, 2001Date of Patent: October 1, 2002Assignee: Impetus AGInventors: Christof Jaenicke, Jörg Grünwald, Benedikt Hänggi
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Publication number: 20020132006Abstract: A coating for masking or reducing the detectable presence of certain characteristic odor or odors, taste or tastes of pharmaceutical preparations, particularly Valerian extracts, is described. The coating comprises from one to three coating compartments, in any combination or as a single-layer amalgam. The first coating compartment comprises a hydroxyalkyl cellulose and an anti-tackiness agent. The second coating compartment may comprise a sugar and at least one anti-tackiness agent. The third coating compartment may comprise a methacrylate copolymer, a hydroxyalkyl cellulose and an anti-tackiness agent.Type: ApplicationFiled: May 30, 2001Publication date: September 19, 2002Inventors: I-Lan T. Sue, Pou-Hsiung Wang, Lori McDonald Smith
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Publication number: 20020122835Abstract: Compositions comprising zinc, magnesium and vitamin B6 and optionally theanine are effective for enhancing muscle and tissue recovery during sleep, following intense physical exercise.Type: ApplicationFiled: March 1, 2001Publication date: September 5, 2002Inventors: Luke R. Bucci, Alan Shugarman, Jeffrey A. Felliciano, Marta Draper Rodriguez
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Patent number: 6436150Abstract: A fabric protectant comprising of a carrier and a plant oil selected from the group consisting of horseradish oil, bay oil, basil oil, calamus oil, ginger oil, palmarosa oil, cinnamon oil, ylang-ylang oil, perilla oil, valerian oil, clove oil, star anise oil, milfoil oil, fennel oil, oregano oil and angelica oil, efficaciously controls fabric-related pests. In addition, a method of protecting fabric which comprises dispersing, spraying, spreading and setting an effective amount of the plant oil selected from the group given above is an excellent method to control fabric-related pests.Type: GrantFiled: February 18, 1999Date of Patent: August 20, 2002Assignee: Sumitomo Chemical Company, LimitedInventors: Keisuke Watanabe, Masayo Sugano
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Publication number: 20020102315Abstract: The invention refers to the herbal composition which consists of: the plant of centaury (Centauri herba) 12.3% by wt., the root of dandelion (Teraxaci radix) 9.7% by wt., the fruit of juniper (Juniperi communis fructus) 6.2% by wt., the plant of nettle (Urticae herba) 7.4% by wt., the root of nettle (Urticae radix) 7.0% by wt., the root of chicory (Cichorii radix) 17.7% by wt., the leaf of black mulberry (Morus nigra folium) 7.4% by wt., the flower of yarrow (Achilleae millefolii flos) 3.5% by wt., the leaf of bilberry (Vaccinii myrtilli folium) 6.6% by wt., the pod of beans (Phaseoli fructus sine semeni) 14.4% by wt., and the root of valerian (Valerianae officinalis radix) 7.8% by wt., and to the medicament against diabetes mellitus type II obtained from it. The medicament is anticipated to be administered perorally in form of tea, a tincture and a pill.Type: ApplicationFiled: September 11, 2001Publication date: August 1, 2002Inventor: Vladimir Leko
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Publication number: 20020064569Abstract: A method of inhibiting at least one symptomology of Restless Leg Syndrome (RLS) and its related disorders, including disorders such as periodic limb movements in sleep (PLMS) and periodic limb movement disorder (PLMD), is disclosed. The method optionally comprising identifying a host, afflicted with Restless Leg Syndrome (RLS) and its related disorders; and administering to the host a pharmaceutically effective amount of Valeriana. A novel method of inhibiting at least one symptomology of Restless Leg Syndrome (RLS) and its related disorders is disclosed.Type: ApplicationFiled: November 28, 2001Publication date: May 30, 2002Inventors: Keith Hoffman, Costas Loullis
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Patent number: 6391346Abstract: An orally administered composition capable of reducing inflammation in animals, preferably humans, while promoting sleep for such animals, contains a therapeutically effective amount of a post-supercritical carbon dioxide hydroalcoholic extract of ginger, therapeutically effective amounts of supercritical carbon dioxide extracts of hops, chamomile, ginger, valerian and melissa; and therapeutically effective amounts of hydroalcoholic extracts of holy basil, turmeric, scutellaria baicalensis, chamomile and hops. The composition is preferably orally administered on a daily basis for at least about 4 weeks.Type: GrantFiled: April 5, 2001Date of Patent: May 21, 2002Inventors: Thomas Newmark, Paul Schulick
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Publication number: 20020058074Abstract: A fabric protectant comprising of a carrier and a plant oil selected from the group consisting of horseradish oil, bay oil, basil oil, calamus oil, ginger oil, palmarosa oil, cinnamon oil, ylang-ylang oil, perilla oil, valerian oil, clove oil, star anise oil, milfoil oil, fennel oil, oregano oil and angelica oil, efficaciously controls fabric-related pests. In addition, a method of protecting fabric which comprises dispersing, spraying, spreading and setting an effective amount of the plant oil selected from the group given above is an excellent method to control fabric-related pests.Type: ApplicationFiled: September 28, 2001Publication date: May 16, 2002Applicant: Sumitomo Chemical Company, LimitedInventors: Keisuke Watanabe, Masayo Sugano
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Publication number: 20020058073Abstract: Compositions and methods for treating neck or shoulder discomfort are provided. The compositions comprise singly or in combination herbals, natural nutritional supplements, minerals and vitamins. Methods of making these compositions are also provided.Type: ApplicationFiled: June 1, 2001Publication date: May 16, 2002Inventor: Yuanjin Tao
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Patent number: 6383526Abstract: A process for preparing a pharmaceutically-active extract of the root of a plant of the family Valerianacae, specifically, Valeriana officinalis L., is described. This process comprises the steps of adding the roots to an alcoholic extraction solvent to form a mixture, wherein the alcoholic extraction solvent comprises between approximately 50% to approximately 100% (v/v) in a remainder of water, and heating the mixture to a temperature of between approximately 70° C. to approximately 80° C. for a period of at least approximately two hours. By this process valerenic acid is obtained in the extract, and the extract has a content of valepotriates and valepotriate degradation products or derivatives that is substantially reduced with respect to the content of valepotriates in the roots, and has a content of valerenic acids that is not substantially reduced with respect to the content of valerenic acids in the roots.Type: GrantFiled: July 21, 2000Date of Patent: May 7, 2002Assignee: Ancile Pharmaceuticals, Inc.Inventors: Michael J. Andrews, Amaresh Basu
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Patent number: 6383527Abstract: Preparations and extracts of valerian, as well as isovaleramide, isovaleric acid, and its pharmaceutically acceptable salts, esters, and substituted amides, and other valerian-related compounds, in combination with NSAIDs exhibit clinically significant pharmacological properties which implicate a treatment for acute muscular aches, strains, and sprains which occur from a localized, external insult to a particular muscle or muscle group outside of, or peripheral to, the CNS. The compositions in question generally are non-cytotoxic and do not elicit weakness or sedative activity at doses that are effective for the symptomatic treatment of such pathological conditions.Type: GrantFiled: February 22, 2001Date of Patent: May 7, 2002Assignee: NPS Pharmaceuticals, Inc.Inventors: Linda D. Artman, Manuel F. Balandrin
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Patent number: 6346283Abstract: A novel method of inhibiting at least one symptomology of Restless Legs Syndrome (RLS) and its related disorders, including disorders such as periodic limb movements in sleep (PLMS) and periodic limb movement disorder (PLMD), is disclosed. Said method optionally comprising identifying a host, preferably a human, afflicted with Restless Legs Syndrome (RLS) and its related disorders; and comprising administering to said host a pharmaceutically effective amount of Valeriana, preferably an extract of Valeriana. A novel method of inhibiting at least one symptomology of Restless Legs Syndrome (RLS) and its related disorders is disclosed.Type: GrantFiled: December 30, 1999Date of Patent: February 12, 2002Assignee: Ancile PharmaceuticalsInventors: Keith Hoffman, Costas Loullis
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Publication number: 20010051191Abstract: A composition and a method for treatment of urinary tract dysfunction and, particularly, non-bacterial cystitis and, even more particularly, non-bacterial chronic interstitial cystitis. The composition primarily relies upon the use of a bioflavonoid and, particularly, that bioflavonoid known as quercetin. The quercetin is mixed with a proteolytic digestive enzyme protease, such as bromelin and papain, as the primary active ingredients. However, the composition may optionally and beneficially include other cystitis affecting agents, such as cranberry, as well as some other active and non-active ingredients.Type: ApplicationFiled: May 2, 2001Publication date: December 13, 2001Inventor: Floyd A. Katske
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Publication number: 20010038863Abstract: A first pharmacologically active substance contained in a pharmaceutical, which acts on a specific biological function, is released according to a predetermined release profile (D.1), FIG. 1, and generates a first activity profile (1.1) that has flank phases with increasing and decreasing activity intensity. For changing such flank phases, an additional pharmacologically active substance is used which acts on the same biological function and which is released according to a release profile (D.2) such that its activity profile (I.2) overlays the first activity profile (I.1) within the flank phase to be changed. For shortening an end flank phase, an additional substance is used whose activity is counter to the activity of the first substance and cancels, reduces, or overpowers this activity in its declining phase. Accordingly, with the aforementioned pharmaceutical, undesirable aftereffects of a pharmacologically active substance, for example, can be prevented.Type: ApplicationFiled: February 23, 2001Publication date: November 8, 2001Inventors: Christof Jaenicke, Jorg Grunwald, Benedikt Hanggi
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Publication number: 20010039296Abstract: A method for preventing and or reducing the symptoms of menopause in women comprises identifying women having or at risk for having such symptoms, and administering to them an effective amount of a composition comprising trans-resveratrol and other compounds that prevent or reduce the symptoms.Type: ApplicationFiled: March 23, 2001Publication date: November 8, 2001Inventors: Debasis Bagchi, Gary Troxel
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Publication number: 20010036486Abstract: A method of treating nicotine addiction or deterring tobacco use in a subject by administering to the subject a therapeutically effective amount of Hypericum perforatum or at least one active component thereof is disclosed. As disclosed, the composition may further comprise a pharmaceutically acceptable carrier. The composition may also comprise a supplementary compound such as L-phenylalanine, L-tyrosine, tryptophan, 5-hydroxy tryptamine, serotonin, calcium carbonate and magnesium oxide, kava-kava, a kava alkaloid, valerian, hops, a passion flower extract, vitamin C, or Echinacea.Type: ApplicationFiled: April 20, 2001Publication date: November 1, 2001Inventors: Norman E. Rosenthal, Richard A. Friedman
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Patent number: 6274176Abstract: An edible composition for use as an anti-inflammatory agent for alleviation of arthritis and gout in mammals. The edible composition is a mixture of at least three, preferably at least seven, herbs selected from the group consisting of Tanacetum parthenium, Zingibar officinale, Curcuma longa, Coriandrum sativum, Centella asiatica, Oenothera biennis, Valeriana officinalis, Tabebuia impetiginosa, Thymus vulgaris and Sambucus nigra. A preferred composition will contain at least Tanacetum parthenium, Zingibar officinale and Curcuma longa. The composition preferably contains the herbs in approximately equal amounts.Type: GrantFiled: July 1, 1999Date of Patent: August 14, 2001Assignee: Chromak Research, Inc.Inventors: Onkar S. Tomer, Peter Glomski, Kripanath Borah
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Publication number: 20010006685Abstract: A fabric protectant comprising of a carrier and a plant oil selected from the group consisting of horseradish oil, bay oil, basil oil, calamus oil, ginger oil, palmarosa oil, cinnamon oil, ylang-ylang oil, perilla oil, valerian oil, clove oil, star anise oil, milfoil oil, fennel oil, oregano oil and angelica oil, efficaciously controls fabric-related pests. In addition, a method of protecting fabric which comprises dispersing, spraying, spreading and setting an effective amount of the plant oil selected from the group given above is an excellent method to control fabric-related pests.Type: ApplicationFiled: February 18, 1999Publication date: July 5, 2001Inventors: KEISUKE WATANABE, MASAYO SUGANO