Containing Or Obtained From Valeriana (i.e., Valeriana Officinalis) Patents (Class 424/733)
  • Patent number: 6544565
    Abstract: A method of inhibiting at least one symptomology of Restless Leg Syndrome (RLS) and its related disorders, including disorders such as periodic limb movements in sleep (PLMS) and periodic limb movement disorder (PLMD), is disclosed. The method optionally comprising identifying a host, afflicted with Restless Leg Syndrome (RLS) and its related disorders; and administering to the host a pharmaceutically effective amount of Valeriana. A novel method of inhibiting at least one symptomology of Restless Leg Syndrome (RLS) and its related disorders is disclosed.
    Type: Grant
    Filed: November 28, 2001
    Date of Patent: April 8, 2003
    Assignee: Ancile Pharmaceuticals, Inc.
    Inventors: Keith Hoffman, Costas Loullis
  • Publication number: 20030054051
    Abstract: This invention relates to a composition for inducing smoking cessation comprising as active ingredient alkaloids from Radix ipecauanhae. In smoking cessation program using the composition, the considerable number of volunteers participated in the program became nausea and thus ultimately to have no craving for smoking.
    Type: Application
    Filed: September 13, 2001
    Publication date: March 20, 2003
    Inventors: Hwa-Mok Park, Byung-Zun Ahn
  • Publication number: 20030054049
    Abstract: The object of the invention is to provide perfumes that is effective on physiologically manifested stresses and the perfume compositions comprising the same that is effective on stress reduction. The invention provides the stress relieving perfumes wherein the active component is valerian oil, especially fatty acid-removed valerian oil, and stress relieving perfume compositions containing the same.
    Type: Application
    Filed: February 13, 2002
    Publication date: March 20, 2003
    Inventors: Ken Shoji, Keiko Sakai
  • Publication number: 20030017220
    Abstract: A process for preparing a pharmaceutically-active extract of the root of a plant of the family Valerianacae, specifically, Valeriana officinalis L., is described. This process comprises the steps of adding the roots to an alcoholic extraction solvent to form a mixture, wherein the alcoholic extraction solvent comprises between approximately 50% to approximately 100% (v/v) in a remainder of water, and heating the mixture to a temperature of between approximately 70° C. to approximately 80° C. for a period of at least approximately two hours. By this process valerenic acid is obtained in the extract, and the extract has a content of valepotriates and valepotriate degradation products or derivatives that is substantially reduced with respect to the content of valepotriates in the roots, and has a content of valerenic acids that is not substantially reduced with respect to the content of valerenic acids in the roots.
    Type: Application
    Filed: April 11, 2002
    Publication date: January 23, 2003
    Inventors: Michael J. Andrews, Amaresh Basu
  • Publication number: 20020192283
    Abstract: A coating for masking or reducing the detectable presence of certain characteristic odor or odors, taste or tastes of pharmaceutical preparations, particularly Valerian extracts, is described. The coating comprises from one to three coating compartments, in any combination or as a single-layer amalgam. The first coating compartment comprises a hydroxyalkyl cellulose and an anti-tackiness agent. The second coating compartment may comprise a sugar and at least one anti-tackiness agent. The third coating compartment may comprise a methacrylate copolymer, a hydroxyalkyl cellulose and an anti-tackiness agent.
    Type: Application
    Filed: May 14, 2002
    Publication date: December 19, 2002
    Inventors: I-Lan T. Sue, Pou-Hsiung Wang
  • Patent number: 6495172
    Abstract: A method of using steam ironing of fabrics as a way of causing reduction of physiological and/or subjective reactivity to stress in a human is provided. The method includes the steps of providing a stress reducing composition comprising one or more of a volatile natural essential oil and water. The composition is adapted to not cause staining of fabrics. The method includes delivering the stress reducing composition into a liquid container of a steam iron and heating the steam iron. The method further includes releasing vapors of the stress reducing composition produced within the liquid container of the steam iron upon heating into ambient air. The method still further includes the step of causing reduction of physiological and/or subjective reactivity to stress in the human by one of more of transdermal ingestion or inhalation of the vapors by the human.
    Type: Grant
    Filed: June 15, 2001
    Date of Patent: December 17, 2002
    Assignee: Procter & Gamble
    Inventors: Paul Amaat France, Arseni V. Radomyselski
  • Patent number: 6458384
    Abstract: A first pharmacologically active substance contained in a pharmaceutical, which acts on a specific biological function, is released according to a predetermined release profile (D.1), FIG. 1, and generates a first activity profile (I.1) that has flank phases with increasing and decreasing activity intensity. For changing such flank phases, an additional pharmacologically active substance is used which acts on the same biological function and which is released according to a release profile (D.2) such that its activity profile (I.2) overlays the first activity profile (I.1) within the flank phase to be changed. For shortening an end flank phase, an additional substance is used whose activity is counter to the activity of the first substance and cancels, reduces, or overpowers this activity in its declining phase. Accordingly, with the aforementioned pharmaceutical, undesirable aftereffects of a pharmacologically active substance, for example, can be prevented.
    Type: Grant
    Filed: February 23, 2001
    Date of Patent: October 1, 2002
    Assignee: Impetus AG
    Inventors: Christof Jaenicke, Jörg Grünwald, Benedikt Hänggi
  • Publication number: 20020132006
    Abstract: A coating for masking or reducing the detectable presence of certain characteristic odor or odors, taste or tastes of pharmaceutical preparations, particularly Valerian extracts, is described. The coating comprises from one to three coating compartments, in any combination or as a single-layer amalgam. The first coating compartment comprises a hydroxyalkyl cellulose and an anti-tackiness agent. The second coating compartment may comprise a sugar and at least one anti-tackiness agent. The third coating compartment may comprise a methacrylate copolymer, a hydroxyalkyl cellulose and an anti-tackiness agent.
    Type: Application
    Filed: May 30, 2001
    Publication date: September 19, 2002
    Inventors: I-Lan T. Sue, Pou-Hsiung Wang, Lori McDonald Smith
  • Publication number: 20020122835
    Abstract: Compositions comprising zinc, magnesium and vitamin B6 and optionally theanine are effective for enhancing muscle and tissue recovery during sleep, following intense physical exercise.
    Type: Application
    Filed: March 1, 2001
    Publication date: September 5, 2002
    Inventors: Luke R. Bucci, Alan Shugarman, Jeffrey A. Felliciano, Marta Draper Rodriguez
  • Patent number: 6436150
    Abstract: A fabric protectant comprising of a carrier and a plant oil selected from the group consisting of horseradish oil, bay oil, basil oil, calamus oil, ginger oil, palmarosa oil, cinnamon oil, ylang-ylang oil, perilla oil, valerian oil, clove oil, star anise oil, milfoil oil, fennel oil, oregano oil and angelica oil, efficaciously controls fabric-related pests. In addition, a method of protecting fabric which comprises dispersing, spraying, spreading and setting an effective amount of the plant oil selected from the group given above is an excellent method to control fabric-related pests.
    Type: Grant
    Filed: February 18, 1999
    Date of Patent: August 20, 2002
    Assignee: Sumitomo Chemical Company, Limited
    Inventors: Keisuke Watanabe, Masayo Sugano
  • Publication number: 20020102315
    Abstract: The invention refers to the herbal composition which consists of: the plant of centaury (Centauri herba) 12.3% by wt., the root of dandelion (Teraxaci radix) 9.7% by wt., the fruit of juniper (Juniperi communis fructus) 6.2% by wt., the plant of nettle (Urticae herba) 7.4% by wt., the root of nettle (Urticae radix) 7.0% by wt., the root of chicory (Cichorii radix) 17.7% by wt., the leaf of black mulberry (Morus nigra folium) 7.4% by wt., the flower of yarrow (Achilleae millefolii flos) 3.5% by wt., the leaf of bilberry (Vaccinii myrtilli folium) 6.6% by wt., the pod of beans (Phaseoli fructus sine semeni) 14.4% by wt., and the root of valerian (Valerianae officinalis radix) 7.8% by wt., and to the medicament against diabetes mellitus type II obtained from it. The medicament is anticipated to be administered perorally in form of tea, a tincture and a pill.
    Type: Application
    Filed: September 11, 2001
    Publication date: August 1, 2002
    Inventor: Vladimir Leko
  • Publication number: 20020064569
    Abstract: A method of inhibiting at least one symptomology of Restless Leg Syndrome (RLS) and its related disorders, including disorders such as periodic limb movements in sleep (PLMS) and periodic limb movement disorder (PLMD), is disclosed. The method optionally comprising identifying a host, afflicted with Restless Leg Syndrome (RLS) and its related disorders; and administering to the host a pharmaceutically effective amount of Valeriana. A novel method of inhibiting at least one symptomology of Restless Leg Syndrome (RLS) and its related disorders is disclosed.
    Type: Application
    Filed: November 28, 2001
    Publication date: May 30, 2002
    Inventors: Keith Hoffman, Costas Loullis
  • Patent number: 6391346
    Abstract: An orally administered composition capable of reducing inflammation in animals, preferably humans, while promoting sleep for such animals, contains a therapeutically effective amount of a post-supercritical carbon dioxide hydroalcoholic extract of ginger, therapeutically effective amounts of supercritical carbon dioxide extracts of hops, chamomile, ginger, valerian and melissa; and therapeutically effective amounts of hydroalcoholic extracts of holy basil, turmeric, scutellaria baicalensis, chamomile and hops. The composition is preferably orally administered on a daily basis for at least about 4 weeks.
    Type: Grant
    Filed: April 5, 2001
    Date of Patent: May 21, 2002
    Inventors: Thomas Newmark, Paul Schulick
  • Publication number: 20020058074
    Abstract: A fabric protectant comprising of a carrier and a plant oil selected from the group consisting of horseradish oil, bay oil, basil oil, calamus oil, ginger oil, palmarosa oil, cinnamon oil, ylang-ylang oil, perilla oil, valerian oil, clove oil, star anise oil, milfoil oil, fennel oil, oregano oil and angelica oil, efficaciously controls fabric-related pests. In addition, a method of protecting fabric which comprises dispersing, spraying, spreading and setting an effective amount of the plant oil selected from the group given above is an excellent method to control fabric-related pests.
    Type: Application
    Filed: September 28, 2001
    Publication date: May 16, 2002
    Applicant: Sumitomo Chemical Company, Limited
    Inventors: Keisuke Watanabe, Masayo Sugano
  • Publication number: 20020058073
    Abstract: Compositions and methods for treating neck or shoulder discomfort are provided. The compositions comprise singly or in combination herbals, natural nutritional supplements, minerals and vitamins. Methods of making these compositions are also provided.
    Type: Application
    Filed: June 1, 2001
    Publication date: May 16, 2002
    Inventor: Yuanjin Tao
  • Patent number: 6383526
    Abstract: A process for preparing a pharmaceutically-active extract of the root of a plant of the family Valerianacae, specifically, Valeriana officinalis L., is described. This process comprises the steps of adding the roots to an alcoholic extraction solvent to form a mixture, wherein the alcoholic extraction solvent comprises between approximately 50% to approximately 100% (v/v) in a remainder of water, and heating the mixture to a temperature of between approximately 70° C. to approximately 80° C. for a period of at least approximately two hours. By this process valerenic acid is obtained in the extract, and the extract has a content of valepotriates and valepotriate degradation products or derivatives that is substantially reduced with respect to the content of valepotriates in the roots, and has a content of valerenic acids that is not substantially reduced with respect to the content of valerenic acids in the roots.
    Type: Grant
    Filed: July 21, 2000
    Date of Patent: May 7, 2002
    Assignee: Ancile Pharmaceuticals, Inc.
    Inventors: Michael J. Andrews, Amaresh Basu
  • Patent number: 6383527
    Abstract: Preparations and extracts of valerian, as well as isovaleramide, isovaleric acid, and its pharmaceutically acceptable salts, esters, and substituted amides, and other valerian-related compounds, in combination with NSAIDs exhibit clinically significant pharmacological properties which implicate a treatment for acute muscular aches, strains, and sprains which occur from a localized, external insult to a particular muscle or muscle group outside of, or peripheral to, the CNS. The compositions in question generally are non-cytotoxic and do not elicit weakness or sedative activity at doses that are effective for the symptomatic treatment of such pathological conditions.
    Type: Grant
    Filed: February 22, 2001
    Date of Patent: May 7, 2002
    Assignee: NPS Pharmaceuticals, Inc.
    Inventors: Linda D. Artman, Manuel F. Balandrin
  • Patent number: 6346283
    Abstract: A novel method of inhibiting at least one symptomology of Restless Legs Syndrome (RLS) and its related disorders, including disorders such as periodic limb movements in sleep (PLMS) and periodic limb movement disorder (PLMD), is disclosed. Said method optionally comprising identifying a host, preferably a human, afflicted with Restless Legs Syndrome (RLS) and its related disorders; and comprising administering to said host a pharmaceutically effective amount of Valeriana, preferably an extract of Valeriana. A novel method of inhibiting at least one symptomology of Restless Legs Syndrome (RLS) and its related disorders is disclosed.
    Type: Grant
    Filed: December 30, 1999
    Date of Patent: February 12, 2002
    Assignee: Ancile Pharmaceuticals
    Inventors: Keith Hoffman, Costas Loullis
  • Publication number: 20010051191
    Abstract: A composition and a method for treatment of urinary tract dysfunction and, particularly, non-bacterial cystitis and, even more particularly, non-bacterial chronic interstitial cystitis. The composition primarily relies upon the use of a bioflavonoid and, particularly, that bioflavonoid known as quercetin. The quercetin is mixed with a proteolytic digestive enzyme protease, such as bromelin and papain, as the primary active ingredients. However, the composition may optionally and beneficially include other cystitis affecting agents, such as cranberry, as well as some other active and non-active ingredients.
    Type: Application
    Filed: May 2, 2001
    Publication date: December 13, 2001
    Inventor: Floyd A. Katske
  • Publication number: 20010038863
    Abstract: A first pharmacologically active substance contained in a pharmaceutical, which acts on a specific biological function, is released according to a predetermined release profile (D.1), FIG. 1, and generates a first activity profile (1.1) that has flank phases with increasing and decreasing activity intensity. For changing such flank phases, an additional pharmacologically active substance is used which acts on the same biological function and which is released according to a release profile (D.2) such that its activity profile (I.2) overlays the first activity profile (I.1) within the flank phase to be changed. For shortening an end flank phase, an additional substance is used whose activity is counter to the activity of the first substance and cancels, reduces, or overpowers this activity in its declining phase. Accordingly, with the aforementioned pharmaceutical, undesirable aftereffects of a pharmacologically active substance, for example, can be prevented.
    Type: Application
    Filed: February 23, 2001
    Publication date: November 8, 2001
    Inventors: Christof Jaenicke, Jorg Grunwald, Benedikt Hanggi
  • Publication number: 20010039296
    Abstract: A method for preventing and or reducing the symptoms of menopause in women comprises identifying women having or at risk for having such symptoms, and administering to them an effective amount of a composition comprising trans-resveratrol and other compounds that prevent or reduce the symptoms.
    Type: Application
    Filed: March 23, 2001
    Publication date: November 8, 2001
    Inventors: Debasis Bagchi, Gary Troxel
  • Publication number: 20010036486
    Abstract: A method of treating nicotine addiction or deterring tobacco use in a subject by administering to the subject a therapeutically effective amount of Hypericum perforatum or at least one active component thereof is disclosed. As disclosed, the composition may further comprise a pharmaceutically acceptable carrier. The composition may also comprise a supplementary compound such as L-phenylalanine, L-tyrosine, tryptophan, 5-hydroxy tryptamine, serotonin, calcium carbonate and magnesium oxide, kava-kava, a kava alkaloid, valerian, hops, a passion flower extract, vitamin C, or Echinacea.
    Type: Application
    Filed: April 20, 2001
    Publication date: November 1, 2001
    Inventors: Norman E. Rosenthal, Richard A. Friedman
  • Patent number: 6274176
    Abstract: An edible composition for use as an anti-inflammatory agent for alleviation of arthritis and gout in mammals. The edible composition is a mixture of at least three, preferably at least seven, herbs selected from the group consisting of Tanacetum parthenium, Zingibar officinale, Curcuma longa, Coriandrum sativum, Centella asiatica, Oenothera biennis, Valeriana officinalis, Tabebuia impetiginosa, Thymus vulgaris and Sambucus nigra. A preferred composition will contain at least Tanacetum parthenium, Zingibar officinale and Curcuma longa. The composition preferably contains the herbs in approximately equal amounts.
    Type: Grant
    Filed: July 1, 1999
    Date of Patent: August 14, 2001
    Assignee: Chromak Research, Inc.
    Inventors: Onkar S. Tomer, Peter Glomski, Kripanath Borah
  • Publication number: 20010006685
    Abstract: A fabric protectant comprising of a carrier and a plant oil selected from the group consisting of horseradish oil, bay oil, basil oil, calamus oil, ginger oil, palmarosa oil, cinnamon oil, ylang-ylang oil, perilla oil, valerian oil, clove oil, star anise oil, milfoil oil, fennel oil, oregano oil and angelica oil, efficaciously controls fabric-related pests. In addition, a method of protecting fabric which comprises dispersing, spraying, spreading and setting an effective amount of the plant oil selected from the group given above is an excellent method to control fabric-related pests.
    Type: Application
    Filed: February 18, 1999
    Publication date: July 5, 2001
    Inventors: KEISUKE WATANABE, MASAYO SUGANO