Abstract: This is about a type of Piper laetispicum C.DC. extract and the preparation method thereof as well as the application of the extract in preparing drugs, healthcare products and food additives for treating and/or preventing diseases related to monoamine transmitters such as 5-hydroxytryptamine, noradrenaline and dopamine. The extract is obtained through impregnating or percolating at normal temperature or ?70° C., or is obtained through supercritical fluid extraction method, and in comparison with the existing reflux method, it has higher alkaloid content and higher biological activity.

Abstract: The present invention describes compositions and methods for treating, preventing and improving the appearance of skin, particularly, treating, preventing, ameliorating, reducing and/or eliminating loss of subcutaneous fat in the skin, wherein the compositions include natural plant constituents that stimulate lipid synthesis. The plant extracts are preferably derived from Rhinacanthus nasutus, Humulus scandens, Sesbania grandiflora, Amorphophallus campanulatu, Pouzolzia pentandra, and Piper betel, and any combinations thereof. The compositions are preferably applied to the skin, or are delivered by directed means, to a site in need thereof.

Abstract: A method and composition for reducing the symptoms of the common cold and flu in a human subject in need thereof, comprising the administration of an effective amount of an aqueous composition having all components dispersed as a dry powder concentrate or dissolved in a decoction therein comprising Black pepper, Cinnamon, Cumin, Ginger, Rose hip, Saffron, and Turmeric with Maple Syrup as a sweetener.

Abstract: The invention provides a method for preparing an herbal extract and a flavor system comprising an herbal extract produced by the process. The invention also provides a flavor system comprising an herbal extract comprising thymol, eugenol, carvacrol and eucalyptol. The invention further provides a flavor system comprising a thyme extract having a minimum inhibitory concentration of less than about 3%. Additionally, the invention provides an oral product comprising a flavor system.

Abstract: The present invention relates to a composition containing an extract of pericapium zanthoxyli for protecting brain cells and improving memory, and the composition of this invention induces an effect of protecting brain cells for modern people under brain damage that is caused by environmental factors, such as various stresses, drinking and smoking habits, therefore, it can be used for medicines and health supplements inducing an effect of preventing, treating degenerative disorders and improving memory.

Abstract: The disclosure provides oral compositions having at least two botanical active ingredients derived from plants. The oral composition also includes an orally acceptable vehicle to deliver an effective amount of the at least two active ingredients in vivo. The botanical active ingredients provide particularly efficacious antimicrobial (antibacterial, antiviral, and/or antifungal), antioxidant, anti-inflammatory, anti-ageing, and or healing properties to the oral compositions.

Abstract: This invention relates to products and methods for improving sensory qualities of meat obtained from livestock. In particular, this invention relates to products and methods for reducing off-odors and off-tastes in meat from uncastrated male pigs (boar taint) or from other livestock fed on pasture. According to the invention, this is obtained by administering a product that contains an inducer of the constitutive androstane receptor (CAR). These include plant products derived from Artemisia spp, Citrus spp., Gingko biloba, Tagetes lucida, as well as vitamin E (alpha tocopherol). The CAR-inducer products of the invention may be used to reduce boar taint and thereby eliminate the need for castration of male pigs.

Abstract: A method for treating a patient suffering from kidney and/or urinary system stones including preparing an infusion from a plant, such as, large or medium sized fully-grown Piper hispidum leaves, and ingesting a specified amount of the infusion over a predetermined period of time, has proven effective in quickly and painlessly dissolving kidney and/or urinary system stones in the patient. This is a major breakthrough in the field of medical healthcare, eliminating the need for expensive and painful surgery, or other invasive medical procedures, such as, laser treatment(s) or shock wave lithotripsy, which are typically followed by a relatively long recuperative period. By comparison, treatment with an infusion is quick, generally about two to three days, without sophisticated and expensive medical equipment, and without any recuperative period.

Abstract: An anti-cough, anti-tussive, and throat soothing synergistic herbal formulation comprising of an extract of Piper cubeba, Glycyrrhiza glabra, Acorus calamus Alpinia galanga, Zingiber officinale and pharmaceutically acceptable additives as a syrup, lozenges or chewable tablets for preventing cracking of voice, dryness of mouth and toning of voice, vocal cord; the present invention also provides a method of preparation of this formulation.

Abstract: The method for making a hair pomade composition includes the steps of melting petroleum jelly over a heated surface and then mixing sesame seed oil, meadowfoam seed oil, pumpkin seed oil, Cyprus oil, basil sweet oil, Rosemary oil, black pepper oil, lemon oil, and Anise oil with the melted petroleum jelly into a mixture. Thereafter, the all-natural hair pomade mixture is solidified.

Abstract: This invention provides a standardized extract of the peppercorns from the plant Zanthoxylum pipertium (Hua Jiao or Sansho). The extract provides an all natural, side effect free method to manage, treat and/or reverse autism, autism spectrum disorders, autistic-like symptoms, Fragile-X, and/or Fragile-X symptoms (FXS) by selectively blocking and halting the enzymatic activity of the kinase PAK.

Abstract: The present invention is a method for the treatment of depression comprising administering to a subject in need thereof a therapeutically effective amount of one or more carbamate compounds of Formula 1 and/or Formula 2 as herein defined and shown below for the treatment of depression. The present invention is directed to a method for the treatment of depression, which includes mono-therapy and alternatively, co-therapy with at least one additional antidepressant.

Abstract: A composition containing a licorice polyphenol and other active ingredient (antioxidant ingredient, polyphenol other than licorice polyphenol or a component relating to lipid absorption or metabolism) is highly safe, can be produced easily, and can be utilized for foods and drinks such as health food, food with health claims (specified health food, food with nutrient function claims) and the like, pharmaceutical products, quasi-drugs, cosmetics and the like. In addition, since the composition has a body fat accumulation suppressing effect, a body fat decomposition promoting effect or energy production promoting effect, it is useful for the treatment of obesity, metabolic syndrome and the like.

Abstract: Disclosed herein is a composition having activity of inhibiting acyl-CoA: cholesterol acyltransf erase, which comprises retrofractamide A, pipercide, piperrolein B, piperchabamide D, pellitorin or combinations thereof, or a pharmaceutically acceptable salt thereof . The composition is effective for preventing and treating vascular diseases, such as hyperlipidemia, arteriosclerosis, etc.

Abstract: A nutritional supplement preparation is provided that includes minerals and trace elements such as vitamin D, calcium, magnesium, selenium, copper, zinc and chromium, as well as at least one catalyst and/or active ingredient, preferably in powder form, which increases and/or improves and/or accelerates the absorption of the minerals and/or trace elements.

Abstract: A compound that contains herbal supplements to increase the frequency and lucidity of a person's erotic or sexual dreams. The compound can be used by anyone wishing to enhance their lucid erotic dreams, or may also be taken by people suffering from jet lag or insomnia. Modes of delivery are by capsule, tablet, soft gel, transdermal patch, liquid, and gum.

Abstract: Fast Asleep is an innovative new product with the latest and most effective delivery system. Fast Asleep comes in a dissolving strip very similar to Listerine®. An herbal composition for inducing sleep while simultaneously enhancing memory, Fast Asleep's oral strips contain a unique blend which provides hormone, natural herb and plant alkaloid. The blend consists of Kava-Kava extract (standardized to 30% kavalactones), Melatonin and Huperzine-A. The hormone and the sleep-inducing natural herb are in a range of 5% to 10% by weight of the composition and the memory-enhancing plant alkaloid is approximately 0.1% by weight of the composition.

Abstract: The formula contains a combination of nutrients ideal for cardiovascular health. Coenzyme Q10 (CoQ10), tocotrienols and tocopherols (potent forms of vitamin E) promote healthy heart function, provide powerful antioxidant protection and support the immune system in its daily defense of the body. The formula also contains a unique tocotrienol complex, derived from the fruit oil of palm trees. Tocotrienols (also known as “super vitamin E”) have been clinically proven to promote healthy cholesterol levels. They inhibit production of cholesterol in the liver and may actually be able to reverse arterial blockage, promoting efficient blood flow supply to the heart muscle.

Abstract: The present invention relates to a method for inhibiting the activity of dipeptidyl peptidase-IV (DPP-IV) and decreasing blood glucose levels.

Abstract: The invention provides a novel herbal preparation useful in treatment of allergy. Formulation(s) comprises of plant preparation or active component of plant extract together with conventional additives to form the oral dosage forms, which includes tablets, capsules and liquid dosage forms viz. syrup and suspension as anti-allergic. Formulation(s) comprises of Tinospora cardifolia, Piper longum, Albizia lebbeck and Curcuma amada. The formulation can be used as solid or liquid or encapsulated as a soft/hard gelatin capsule for easy consumption as solid or liquid dosage forms.

Abstract: A method of treating CD33+ acute and chronic myeloid leukemia in animals including humans, using fraction nos. 1 and 9 obtained from water: methanol fraction by column chromatography, with ratio of water and methanol ranging between 1:5 to 5:1, wherein said water:methanol fraction is obtained from the polar extract of Piper betel by HPLC, with retention time of 3.6 and 24.0 minutes respectively, with said fractions used both individually, and in combination, and a composition comprising the said fraction nos. 1 and 9.

Abstract: A preparation for oral administration, in which plant material is comminuted and treated by mixing thoroughly with an extractant. After mixing, porous inorganic particles are added to the resulting suspension, thoroughly mixed with mixture and dried. The preparation provides a homogeneous distribution of the active ingredient as well as long stability and good bioavailability of the active ingredient.

Abstract: A method of producing a processed kava product involves using an extraction solvent, such as liquid CO2, to preferentially extract different kavalactones from the source material at different rates. By controlling the extraction parameters and stopping the extraction before all of the kavalactones have been extracted or allowing the extracted kavalactones to be preferentially precipitated in one or more collection environments, a processed kava product can be produced that has a kavalactone distribution profile that can differ substantially from that of the source material. As a result, roots from a less desirable kava cultivar can be used to produce a processed kava product which has a kavalactone distribution profile that is similar to that of a highly desired cultivar. A material having a preferred kavalactone distribution profile is also disclosed. The kava paste can be further processed to produce a dry flowable powder suitable for use in, e.g., a tableting formula.

Abstract: The present invention relates to a method for providing ?-glucosidase inhibition to a subject by administering a pharmaceutical composition comprising a ?-glucosidase inhibitory agent selected from pipataline (formula 1a), sesamin (formula 1b), pellitorine (Formula 1c), guineensine (Formula 1d) and brachystamide-B (formula 1e) having therapeutic application for diabetes mellitus, cancer, viral diseases such as hepatitis B and C, HIV, AIDS etc; also the invention provides a process for the isolation of said ?-glucosidase inhibitory agent from the plant source Piper longum in significant yields.

Abstract: The invention relates to an herbal composition comprising extract of plant Moringa Oleifera, a member of family Moringaceae, plant Piper Nigrum, a member of family Piperaceae and plant Nicotiana Tabacum, a member of family Solanaceae for treating or alleviating of vascular headaches, neurological conditions and neurodegenerative diseases. The invention also reveals a method of preparing and using the composition.

Abstract: This invention relates to use of betel leaf extract to induce IFN? from human peripheral blood mononuclear cells and as a Th1 type immuno modulator, wherein the said method comprises the steps of, preparing water extract of betel leaf, preparation of human peripheral blood mononuclear cells, incubation of hPBMC with betel leaf extract for a period of 18–48 hours, extraction of RNA for cytokine specific RT-PCR or for flow cytometry for the detection of intracellular cytokine protein, subjecting RNA for RT-PCR to obtain PCR products using IFN? specific known primers, and enhancement of IFN? as reflected by IFN? specific band.

Abstract: A pesticide consisting of a mixture of sulfur well water and seven edible ingredients, which becomes lethal to fire ants and termites when mixed together, in a liquid, granular, spray or paste form.

Abstract: The present invention relates to a herbal health protective, promotive and disease preventive nutraceutical herbal formulation(s) for diabetics, and also relates to a process for the preparation of a herbal health protective, promotive and disease preventive nutraceutical herbal formulation as food supplement to ameliorate the general health of diabetics, said formulation comprises the base product of microwave roasted seed powders mixture from selected genera of Glycine, Cicer, Phaseolus, Cyamompsis, Mucuna, Hordeum, Amaranthus and Fagopyrum, fortified with herbs/medicinal plants used are selected from the genera of Gymnema, Momordica, Syzgium, Pterocarpus, Trigonella, Cinnamomum, Withania, Coccinia, Pueraria, Asparagus, Boerhaavia and Aegle and also some other ingredients like Piper longum, Chlorophytum tuberosum, Curcuma longa and Elettaria cardamomum were also added to get the final nutraceutical product(s); the nutraceuticals are with optimum nutrition, non toxic, natural herbal plant products, easy to d

Abstract: The present invention is a method for enhancing the efficacy of an active ingredient in a human comprising: administering to said human a product comprising: a kavalactone component and an active ingredient, wherein said active ingredient is selected from the group consisting of a therapeutic, a pharmaceutical, a nutraceutical and a botanical, and wherein said kavalactone component comprises a methysticin component, a dihydromethysticin component, a desmethoxyyangonin component, a yangonin component, a dihydrokavain component, and a kavain component, and wherein said kavalactone component is between about 0.1% to about 75%, by mass, of said product.

Abstract: A composition for treating inflammation and pain in mammals, particularly humans. Effective amounts of a boswellic acid, a curcuminoid, a gingerol, a capsaicinoid, a bioflavonoid, and a vitamin C source, in various combinations, all preferably from a botanical source, are blended to form a dose for oral administration. Administration of the dose provides relief from pain and inflammation of connective tissue. The dose may be administered as a tablet, a liquid, or a powder.

Abstract: The present invention relates to a novel synergistic herbal composition for the treatment of gastric ulcer, a method for preparing said synergistic herbal composition and a process for the treatment of gastric ulcer using said composition and more particularly, the present invention relates to a novel synergistic herbal composition which is effective against pyloric ligation induced ulcer model and histamine induced ulcer model.

Abstract: The compositions of this invention comprise a mixture of (1) phenylalanine and a dietary food supplement, (2) leucine and a dietary food supplement, and (3) hydrocinnamic acid and a dietary food supplement. The compositions are used for medicinal purposes to alleviate a variety of maladies.

Abstract: The invention concerns a formulation containing phosphatidylserine (PS) and/or lyso-phosphatidylserine for preventing and treating mental and physical stress states, where the phosphatidylserine is, among others, combined with plant extracts or essences. Daily doses of 50 to 1000 mg PS are envisaged within the scope of the present invention which are administered over a maximum period of six months. Preferred subjects are humans of 10 to 50 years of age.

Abstract: The present invention relates to a herbal health protective, promotive neutraceutical formulation for women, human expectant mothers and lactating mothers, and also relates to a process for the preparation of custom made herbal health protective, promotive nutraceutical formulations as food supplements to ameliorate the general health of females with optimum nutrients, said process comprises the base product of microwave oven roasted seed powders mixture from selected genera of Glycine, Phaseolus, Cicer, Psophocarpus, Mucuna, Triticum, Hordeum, Amaranthus, Chenopodium and Fagopyrum, fortified with the natural herbs/medicinal plants extract from the genera Centella, Withania, Pueraria, Asparagus, Chlorophytum, Boerhaavia, Sida, Saraca and also some other ingredients like pale sugar powder, jaggery, milk powder, coca powder, Elettaria cardamomum (Elaichi) powder, Piper longum (Pippali) fruit powder, Myristica fragrans (Jaiphal) fruit powder were also added to get the final nutraceuticals; the nutraceuticals are

Abstract: The present invention is directed to a sensate composition including at least one cooling sensate, warming sensate and tingling sensate. The tingling sensate is at least one of Jambu Oleoresin and Spilanthol. The present invention is further directed to a method of using the sensate composition in a food, pharmaceutical or personal care product.

Abstract: Novel oil extracts from Angiosperm and Gymnosperm plants and other-plant biomass from human, veterinary, birds, aquatic species, microbial and mycological sources useful in human, veterinary and agricultural, mycological and microbiological applications are described. Methods of preparation of these extracts in oil and methods of application and administration are also described.

Abstract: The present invention provides a pharmaceutical that includes, in combination, a resinate and an aversive agent. The resinate includes an ion exchange resin and an drug. The drug is a controlled substance. In variants of the invention, both the aversive agent and the controlled substance are loaded onto the ion exchange resin; the aversive agent is loaded onto the ion exchange resin, and the controlled substance is not loaded onto the ion exchange resin; the controlled substance is loaded onto the ion exchange resin, and the aversive agent is not loaded onto the ion exchange resin; or, the controlled substance is loaded onto a first ion exchange resin, and the aversive agent is loaded onto an ion exchange resin different from the first ion exchange resin.

Abstract: An anti-cough, anti-tussive, and throat soothing synergistic herbal formulation comprising of an extract of Piper cubeba, Glycyrrhiza glabra, Acorus calamus Alpinia galanga, Zingiber officinale and pharmaceutically acceptable additives as a syrup, lozenges or chewable tablets for preventing cracking of voice, dryness of mouth and toning of voice, vocal cord; the present invention also provides a method of preparation of this formulation.

Abstract: This invention relates to methods of extracting and purifying bioactive substances from various plants and herbs. More specifically the invention relates to methods of extracting and separating bioactive substances from various plants and herbs, such as Kava root, Byrsonima species, Aesculus californica, Crataegus mexicana, Simmondsia chinensis, Pfaffia species, Alternanthera repens, Bursera species, Turnera species, Perezia species, Heimia salicifolia, Psidium species, Enterlobium species, Ptychopetalum olacoides, Liriosma ovata, and Chaunochiton kappleri, using supercritical fluid extraction and/or fluorocarbon solvent extract. The present invention further relates to separation of bioactive substances contained in extracts using packed column supercritical fluid chromatography or HPLC where dense gas with or without modifiers is the mobile phase.

Abstract: The present invention relating to a herbal antiallergic composition which comprises a synergistic mixture of extracts from the fruits of Terminalia chebula, bark of Albizia lebbeck, Terminalia bellerica and Emblica officinalis. The present invention also contains the fruits of Piper longum, Piper nigrum and of rhizomes of Zingiber officinale and thoroughly mixed to get the final composition which has potent antiallergic activity. The invention also relates to a process for the preparation of such composition. The composition is particularly useful for the treatment of allergic conditions.

Abstract: The present invention relates to a method for providing &agr;-glucosidase inhibition to a subject by administering a pharmaceutical composition comprising a &agr;-glucosidase inhibitory agent selected from pipataline (formula 1a), sesamin (formula 1b), pellitorine (Formula 1c), guineensine (Formula 1d) and brachystamide-B (formula 1e) having therapeutic application for diabetes mellitus, cancer, viral diseases such as hepatitis B and C, HIV, AIDS etc; also the invention provides a process for the isolation of said &agr;-glucosidase inhibitory agent from the plant source Piper longum in significant yields.

Abstract: A method of producing a processed kava product involves using an extraction solvent, such as liquid CO2, to preferentially extract different kavalactones from the source material at different rates. By controlling the extraction parameters and stopping the extraction before all of the kavalactones have been extracted or allowing the extracted kavalactones to be preferentially precipitated in one or more collection environments, a processed kava product can be produced that has a kavalactone distribution profile that can differ substantially from that of the source material. As a result, roots from a less desirable kava cultivar can be used to produce a processed kava product which has a kavalactone distribution profile that is similar to that of a highly desired cultivar. The kava paste can be further processed to produce a dry flowable powder suitable for use in, e.g., a tableting formula. A rapid dissolve tablet formulation for use in the delivery of kavalactones and other botanicals is also disclosed.

Abstract: The present invention is a method for enhancing the efficacy of an active ingredient in a human comprising: administering to said human a product comprising: a kavalactone component and an active ingredient, wherein said active ingredient is selected from the group consisting of a therapeutic, a pharmaceutical, a nutraceutical and a botanical, and wherein said kavalactone component comprises a methysticin component, a dihydromethysticin component, a desmethoxyyangonin component, a yangonin component, a dihydrokavain component, and a kavain component, and wherein said kavalactone component is between about 0.1% to about 75%, by mass, of said product.

Abstract: The invention concerns a method and an installation for setting in adsorbed state, on a porous support, compounds contained in a product comprising a first step which consists in extracting the compounds by contacting the product with at least a solvent at supercritical pressure to obtain a mixture of extracts and solvent. The method is characterized in that it comprises a second step which consists in eliminating the water contained in the mixture of extracts and solvent, adjusting the temperature and pressure conditions so as to obtain, a first phase consisting of solvent in gaseous state and a second phase consisting of a mixture of liquids formed of solvent and extracts of the products; causing said two phases to trickle through a porous support adapted to adsorb the extracts; vaporizing the solvent contained in the second phase.

Abstract: The present invention provides a method of treating acute and chronic myeloid leukemia (AML & CML) and lymphoid leukemia, said method comprising administering a pharmaceutical composition comprising pharmaceutically effective amount of chlorogenic acid (CA) and 3-o-p-Coumaryl quinic acid (PCQ) isolated from any plant parts of Piper betel or any other source, both individually or in a synergistic combination optionally along with pharmaceutically acceptable additives.

Abstract: The present invention relates to a bioenhancing/bioavailability-facilitating composition comprising:

Abstract: A new herbal-based composition and method for treatment of CD33+ acute and chronic myeloid leukemia by Piper betel leaf extracts, and to provide a process for the isolation of active fractions from leaves or any other plant parts of Piper betel to treat CD3 3+ AML and CML with a simplified method of isolation of active components from all plant parts of Piper betel possessing biological activities relevant to the treatment of CD33+ AML and CML.

Abstract: The invention relates to an herbal composition comprising extract of plant Moringa Oleifera, a member of family Moringaceae, plant Piper Nigrum, a member of family Piperaceae and plant Nicotiana Tabacum, a member of family Solanaceae for treating or alleviating of vascular headaches, neurological conditions and neurodegenerative diseases. The invention also reveals a method of preparing and using the composition.

Abstract: Disclosed is a process for producing powders from high viscosity fluids including mixing a mixture comprising a high viscosity fluid and at least one absorbing agent until a dry dispersion is produced. The process does not require the need for water or organic solvents, and is therefore non-aqueous in nature. Also disclosed are pharmaceutical compositions that include a high viscosity fluid, and at least one absorbing agent, wherein the percentage of high viscosity fluid in a finished dry powder is greater than 30%. In addition, there is disclosed a process for conversion of the alpha acids in hops extract to iso-alpha acids, and pharmaceutical compositions thereof.

Abstract: The present invention relates to herbal composition for the treatment of chronic respiratory disorders such as cold, cough, allergic asthma, seasonal allergic rhinitis, pharyngitis, laryngitis and the like and a process for preparing the same.