Containing Or Obtained From Cucumbrits (e.g., Gourds Such As Pumpkin, Squash, Cucumber, Etc.) Patents (Class 424/758)
  • Publication number: 20030165533
    Abstract: The invention relates to disclose some Chinese formula for psoriasis. Whether treatment for psoriasis is targeted at both the hyperproliferative and inflammatory aspect of the topical therapy. Specially, the administration dosage is soft gel, cream, tincture and aerosol etc. topical dosages.
    Type: Application
    Filed: January 24, 2003
    Publication date: September 4, 2003
    Inventors: Hsu-Shan Huang, Rong Fu Chen
  • Publication number: 20030157175
    Abstract: There is provided a method of preparing an unsaturated fatty acid dry concentrate, wherein a substance comprising at least one unsaturated fatty acid is applied on a biologically inert matrix having a large surface area and is subsequently dried, as well as a composition comprising at least one unsaturated fatty acid and foods, beverages, drugs comprising this composition.
    Type: Application
    Filed: April 14, 2003
    Publication date: August 21, 2003
    Inventors: Norbert Fuchs, Peter Kossler
  • Publication number: 20030143291
    Abstract: Herbal compositions and methods suitable for weight loss management and for treating diabetes are disclosed. The compositions comprise Ferula hermonis or an extract thereof, or Ferula hermonis with selected herbs, extracts thereof, and mixture thereof. The methods of reducing weight, and treating diabetes in patients involve oral administration of the compositions. The invention further relates to a method of extracting and standardizing Ferula hermonis extracts and tincture useful for human health.
    Type: Application
    Filed: January 31, 2002
    Publication date: July 31, 2003
    Inventor: Yousry M.A. Naguib
  • Patent number: 6576274
    Abstract: Biologically active extracts of celery seed are produced by controlled ethanolic extraction, distillation and drying, and further processing by supercritical fluid extractions (SFE), and may be further fractionated by column fractionation, distillation, LiAlH reduction and the like. These extracts possess activity for the treatment and prevention of acute and chronic pain, inflammation and gastrointestinal irritation.
    Type: Grant
    Filed: October 26, 2001
    Date of Patent: June 10, 2003
    Assignee: International Celery Development Alliance Pty. LTD
    Inventors: Desley Ethel Butters, Craig Kendall Charles Davis, Ross Peter McGeary, Michael Christopher Powanda, Kim Drummond Rainsford, Michael Wellesley Whitehouse
  • Publication number: 20030104083
    Abstract: Compositions are described comprising at least partially defatted meal from a plant source containing protein-bound tryptophan, preferably squash seeds, and, optionally, a carbohydrate source provided in an amount capable of facilitating transport of in vivo generated tryptophan across the blood brain barrier. Also described are dietary supplements, foods and beverages comprising the composition of the invention to reduce anxiety.
    Type: Application
    Filed: November 8, 2002
    Publication date: June 5, 2003
    Inventors: Susan P. Hudson, Craig J. Hudson
  • Publication number: 20030099728
    Abstract: An anti-aromatase pharmaceutical composition, consisting of in capsule or dose to contain
    Type: Application
    Filed: June 21, 2001
    Publication date: May 29, 2003
    Inventor: Michael Donald Farley
  • Publication number: 20030091659
    Abstract: There is disclosed a topical composition having substantially undifferentiated plant seed cells and, preferably, a pharmaceutically or cosmetically acceptable vehicle. There is also a method for topically applying the composition. There are also methods for delivering a consistent level of an active to skin, nail, lips and/or hair and for enhancing the therapeutic efficacy of a topical composition having substantially undifferentiated plant seed cells.
    Type: Application
    Filed: November 9, 2001
    Publication date: May 15, 2003
    Applicant: AVON PRODUCTS, INC.
    Inventors: Michelle Lu, Gopinathan Menon, Michele Duggan
  • Publication number: 20030086949
    Abstract: A method of testing a substance potentially active in the field of lipolysis comprising: preparing a substrate containing at least one triacylglycerol; placing this substrate in contact with a substance potentially active in the field of lipolysis, and with a lipoprotein lipase, in the presence of a cofactor of lipoprotein lipase, for a period of time sufficient to release at least in part one fatty acid of the triacylglycerol; and determining the capacity of inhibition of the release of the fatty acid resulting from the activity of the lipoprotein lipase, under the action of said potentially active substance, and evaluating the result of the inhibition which is either compared to the result obtained in the absence of the potentially active substance tested or compared with the result obtained in the presence of a known inhibitor acting as reference. Cosmetic and pharmaceutical uses are described.
    Type: Application
    Filed: June 25, 2001
    Publication date: May 8, 2003
    Applicant: COLETICA
    Inventors: Eric Perrier, Delphine Rival, Valerie Lamy
  • Publication number: 20030082168
    Abstract: Compositions and methods for facilitating weight loss by inhibiting carbohydrate absorption, enhancing lipolysis, and modulating the metabolism of glucose in a human. The compositions comprise wheat alpha amylase, conjugated linoleic acid, Momordica charantia, lipotrophic vitamins and green tea.
    Type: Application
    Filed: October 22, 2001
    Publication date: May 1, 2003
    Inventor: Inna Yegorova
  • Publication number: 20030064048
    Abstract: The present invention utilizes natural and/or synthetic serine protease inhibitory agents or botanical extracts containing serine protease inhibitory activity, with or without the addition of one or more isoflavones and/or additional natural extracts containing one or more isoflavones, and their ability to affect changes in mammalian hair growth, hair follicle and hair shaft size and hair pigmentation.
    Type: Application
    Filed: September 23, 2002
    Publication date: April 3, 2003
    Inventors: Miri Seiberg, Stanley S. Shapiro, Jue-Chen Liu, Jonathan Miller
  • Publication number: 20030049225
    Abstract: A novel cosmetic preparation can be obtained by incorporating goya (momordica charantia) fruit and leaves into generic paraffin and cosmetic clay. The unique result can be used by estheticians in providing facial masks and cosmetic skin applications in beauty salons or spas and by individuals for similar cosmetic purposes at home.
    Type: Application
    Filed: September 7, 2002
    Publication date: March 13, 2003
    Inventor: Mieko Arashiro Rucker
  • Publication number: 20030031732
    Abstract: Disclosed is an anti-fatigue and nutritious tonic agent containing powder of wild ginseng, optionally in admixture with a herb medicine, or water extract of the powder, which has remarkably enhanced anti-fatigue, and nutrition and tonic effects as compared with agents containing cultivated ginseng.
    Type: Application
    Filed: January 25, 2002
    Publication date: February 13, 2003
    Inventors: Won Kyu Kim, Kye Won Lee, Sun Jung Lee, Bong Jun Kim, Hye Young Lee, Chul Hong Park, Dong Soo Kim, Kyeong Bum Choi, Eun Joung Yoo
  • Publication number: 20030012811
    Abstract: A device 10 for use in delivering an aroma, the device comprising lint 4 or similar material impregnated with the substance giving the desired aroma, the lint being incorporated into an adhesive plaster or patch 2 for application to the skin.
    Type: Application
    Filed: September 12, 2002
    Publication date: January 16, 2003
    Inventor: Elizabeth Paul
  • Patent number: 6503543
    Abstract: Compositions are described comprising at least partially defatted meal from a plant source naturally containing tryptophan, preferably squash seeds, and a carbohydrate source provided in an amount capable of facilitating transport of the tryptophan across the blood brain barrier. Also described are dietary supplements, foods and beverages comprising the composition of the invention to induce sleep or provide tryptophan supplementation to individuals in need thereof.
    Type: Grant
    Filed: May 26, 2000
    Date of Patent: January 7, 2003
    Inventors: Craig J. Hudson, Susan P. Hudson
  • Publication number: 20020192311
    Abstract: A process for producing an antibacterial substance which comprises disintegrating at least a part of a plant tissue and releasing the antibacterial substance therefrom; and antibacterial or bacteriostatic compositions containing the antibacterial substance thus obtained as the active ingredient. By using the above process and compositions, the proliferation of spore-forming bacteria can be efficiently inhibited.
    Type: Application
    Filed: May 22, 2002
    Publication date: December 19, 2002
    Inventor: Takuo Sakai
  • Publication number: 20020193310
    Abstract: A water soluble extract of M.charantia named MC6, methods for its preparation and methods for its use in the treatment of hyperglycemic disorders are provided. The active MC6 is characterized by moving as a single band on SDS-PAGE having a molecular weight of less than 10 kDal, and by comprising three peptides. Also provided is a peptide component of MC6 named MC6.1, as well as analogues and mimetics thereof. The active MC6, MC 6.1, MC6.2, and MC6.3 exhibit hypoglycemic activity, even following oral administration. Also provided are methods of using the active agents to treat hyperglycemic disorders, particularly diabetes, where the active agents are preferably orally administered.
    Type: Application
    Filed: March 21, 2002
    Publication date: December 19, 2002
    Inventors: Bishwajit Nag, Satyanarayana Medicherla, Somesh D. Sharma
  • Publication number: 20020168388
    Abstract: The invention relates to cosmetic compositions for topical application for counteracting UV radiation induced skin damage comprising as active substances a first component which comprises inactivated bacteria selected from the group consisting of the genus Bifidobacterium, Actinomycetaceae, Propionimycetaceae, Lactobacillaceae and Coryneform bacteria and a second component which comprises an extract of plant extracellular matrix. Preferably, the plant extracellular matrix is selected from the group consisting of glycoproteins, carbohydrate polymers and arabinogalactan proteins. Processes for using the cosmetic compositions are also described.
    Type: Application
    Filed: November 5, 2001
    Publication date: November 14, 2002
    Inventors: Stefan Borchert, Rolf-Dieter Petersen
  • Patent number: 6461627
    Abstract: Skin preparations for external use and cosmetics which contain a fermented soybean extract prepared by extracting with an organic solvent a fermentation product obtained by treating a soybean extract with one or more microorganisms selected from bifidobacteria. These preparations are excellent in the effects of relieving wrinkles and ameliorating rough skin.
    Type: Grant
    Filed: April 3, 2001
    Date of Patent: October 8, 2002
    Assignee: Kabushiki Kaisha Yakult Honsha
    Inventors: Minoru Ichioka, Toshiro Sone, Tomoko Hanamizu, Makoto Ohwaki, Katsuyoshi Chiba, Koji Miyazaki, Yoshio Hiraki, Satoshi Yoshikawa
  • Publication number: 20020141955
    Abstract: A cosmetic composition includes a carrier, a skin-whitening agent, and sodium magnesium silicate. The sodium magnesium silicate is present in an amount effective to slow decomposition of the composition. A method of slowing the decomposition of a cosmetic composition containing a skin-whitening agent includes adding an effective amount of a sodium magnesium silicate to the composition.
    Type: Application
    Filed: October 25, 2001
    Publication date: October 3, 2002
    Applicant: AMWAY CORPORATION
    Inventors: Amy C. Zimmerman, Ruth Elaine Harris
  • Publication number: 20020071846
    Abstract: The present invention provides novel adjuvants which comprise oil bodies. The invention also provides vaccine formulations comprising oil bodies and an antigen and methods for preparing the vaccines and the use of the vaccines to elicit an immune response.
    Type: Application
    Filed: June 15, 2001
    Publication date: June 13, 2002
    Inventors: Harm M. Deckers, Gijs Van Rooijen, Joseph Boothe, Janis Goll, Maurice M. Moloney, Anthony B. Schryvers, Joenel Alcantara, Wendy A. Hutchins
  • Patent number: 6379718
    Abstract: Novel herbal extracts provide potent efficacy in the treatment of acne and furuncle. The formulated extracts of Momordica charantia L. are from either the whole plant or parts of the plant. The extracts have been formulated into aqueous solution, pads, and/or lotion. These formulations have been provided to treat acne and furuncle 2 to 3 times a day. It has demonstrated the ability to manage various grades of acne, from mild, moderate to severe, which include comedos, papules, pustules and nodules. Significant improvement is visible within five days. There are no observed either long-term or short-term side reactions.
    Type: Grant
    Filed: December 21, 2000
    Date of Patent: April 30, 2002
    Inventor: Kaijun Ren
  • Publication number: 20020028257
    Abstract: Disclosed herein are novel compositions and/or formulations containing minoxidil as an active ingredient in combination with other active agents and/or enhancer agents (e.g., saw palmetto extract and nettle root extract) which increase the hair growth capability of the composition. Also disclosed are methods of using the novel compositions to treat male patterned baldness and to stimulate hair growth on the scalp, including both the apex and frontal regions of the scalp.
    Type: Application
    Filed: February 20, 2001
    Publication date: March 7, 2002
    Inventors: Chris Catalfo, Fred Mussari, Stephen H. Perry
  • Patent number: 6352728
    Abstract: Biologically active extracts of celery seed are produced by controlled ethanolic extraction, distillation and drying, and further processing by supercritical fluid extractions (SFE), and may be further fractionated by column fractionation, distillation, LiAIH reduction and the like. These extracts possess activity for the treatment and prevention of acute and chronic pain, inflammation and gastrointestinal irritation.
    Type: Grant
    Filed: November 2, 1999
    Date of Patent: March 5, 2002
    Assignee: International Celery Development Alliance Pty. Ltd.
    Inventors: Desley Ethel Butters, Craig Kendall Charles Davis, Ross Peter McGeary, Michael Christopher Powanda, Kim Drummond Rainsford, Michael Wellesley Whitehouse
  • Publication number: 20020025349
    Abstract: The invention provides a synergistic oral liquid herbal composition falling under the category of “Asavas” and “Arishtas”, useful for management of diabetes, said composition comprising a therapeutically effective amount of plant extracts, self-generated ethanol to the extent of 7 to 12% v/v and having not more than 1 to 3% w/w of sugar content and also provides a novel method for the manufacture of herbal compositions in liquid oral dosage form containing a limited amount of self generated alcohol.
    Type: Application
    Filed: May 2, 2001
    Publication date: February 28, 2002
    Inventors: Narasimha Baba Brindavanam, Chandrakant Katiyar, Yadlapalli Venkateswara Rao
  • Patent number: 6350432
    Abstract: A pharmaceutical composition solubilized in a propellant that can be administered buccally or to the lungs using a metered dose dispenser is provided. The composition comprises a pharmaceutical agent; glycerin and/or polyglycerin; phenol and/or methyl phenol; and at least one absorption enhancing compound. A pressurized container with the composition and a methods of making the composition are also provided.
    Type: Grant
    Filed: March 19, 1999
    Date of Patent: February 26, 2002
    Assignee: Generex Pharmaceuticals Incorporated
    Inventor: Pankaj Modi
  • Publication number: 20020004049
    Abstract: Compositions are described comprising at least partially defatted meal from a plant source containing protein-bound tryptophan, preferably squash seeds, and, optionally, a carbohydrate source provided in an amount capable of facilitating transport of in vivo generated tryptophan across the blood brain barrier. Also described are dietary supplements, foods and beverages comprising the composition of the invention to induce sleep or provide tryptophan supplementation to individuals in need thereof.
    Type: Application
    Filed: July 11, 2001
    Publication date: January 10, 2002
    Inventors: Susan P. Hudson, Craig J. Hudson
  • Patent number: 6315984
    Abstract: A pressurized container with an aerosol pharmaceutical formulation, and a process for making the formulation, are provided. The formulation comprises a pharmaceutical agent, a phenol, glycerin or polyglycerin, and an additional ingredient such as an alkali metal alkyl sulfate, polidocanol alkyl ether or the like. The formulation is placed in the pressurized container, which is then charged with a propellant. A method of treating a medical condition, by spraying the formulation into the mouth or lungs, is also provided.
    Type: Grant
    Filed: September 3, 1999
    Date of Patent: November 13, 2001
    Assignee: Generex Pharmaceuticals, Inc.
    Inventor: Pankaj Modi
  • Patent number: 6312737
    Abstract: The invention includes a method of inducing apoptosis in cancer cells by administering an extract of Melothria indica Lou to the cancer cells. The invention also includes a method of using an extract of Melothria indica Lou to induce apoptosis in cancer cells by administering the extract to the cancer cells. The cancer cells can be leukemia cells and prostate cancer cells. Further included in the invention is a method for purifying the Melothria indica Lou into an extract used for inducing apoptosis in cancer cells.
    Type: Grant
    Filed: May 10, 2000
    Date of Patent: November 6, 2001
    Assignee: Ambryx Biotechnology, Inc.
    Inventor: David Tsai
  • Patent number: 6312665
    Abstract: A mixed micellar aerosol pharmaceutical formulation is provided. The formulation comprises a pharmaceutical agent, an alkali metal alkyl sulphate, at least three micelle-forming compounds, a phenol and a propellant. The propellant provides enchanced absorption of the pharmaceutical agent in the buccal region. A process of making and a method of administering the composition are also included.
    Type: Grant
    Filed: August 31, 1999
    Date of Patent: November 6, 2001
    Assignee: Generex Pharmaceuticals Incorporated
    Inventor: Pankaj Modi
  • Publication number: 20010021399
    Abstract: Methods of inducing weight loss and treating adult-onset diabetes in a mammal in need thereof by administering to the mammal Momordica lectin or pokeweed mitogen chloroform precipitatable fraction. Lectin pharmaceutical compositions are also disclosed.
    Type: Application
    Filed: April 20, 2001
    Publication date: September 13, 2001
    Inventor: Douglas D. Lazarus
  • Patent number: 6261607
    Abstract: An herbal composition which can help promote prostate health in men is prepared from saw palmetto, green tea, pumpkin seed oil, ginger, dual urtica root extracts, selenium, watermelon and rosemary. The composition contains therapeutically effective amounts of: supercritical extracts of saw palmetto, ginger, and rosemary, regular or supercritical extracts of green tea, pumpkin seed oil and urtica; selenium; and watermelon. In addition to promoting prostate health, the herbal composition of this invention normalizes urine flow and promotes healthy sexual function and performance. The composition also contains constituents which inhibit 5-lipoxygenase, thereby promoting normal prostate cell growth, and anti-aging constituents that inactivate free radicals, thereby providing antioxidant benefits. The composition is preferably administered orally or parenterally.
    Type: Grant
    Filed: February 25, 2000
    Date of Patent: July 17, 2001
    Inventors: Thomas Newmark, Paul Schulick