Containing Or Obtained From Cactaceae (e.g., Cactus Such As Opuntia, Prickly Pear, Cereus, Selenicereus, Etc.) Patents (Class 424/767)
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Publication number: 20040052870Abstract: The present invention is directed toward a method for inhibiting COX-2 in an organism. In particular, the method is preferably directed toward selectively inhibiting COX-2 in an organism. The method comprises the step of administering to the organism an organic extract isolated from an edible plant wherein such extract inhibits COX-2 A method to purify a composition that exhibits COX-2 inhibition and COX-2 selective inhibition from the organic extract is also provided. In addition, a method for treating and/or preventing COX-2 mediated inflammation or inflammation-associated disorders in an organism is provided.Type: ApplicationFiled: September 30, 2003Publication date: March 18, 2004Inventors: Mark G. Obukowicz, Susan L. Hummert
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Publication number: 20030228375Abstract: This invention provides compositions and methods related to the administration of deer antler, one or more nor-testosterone precursors, and one or more testosterone precursors, to increase testosterone levels, treat sexual dysfunction, improve sexual function, improve energy, enhance feelings of well-being and increase muscle mass in males. This invention also provides for inhibitors of the enzymes aromatase and/or 5-alpha reductase, to support testosterone levels and avoid undesirable metabolites.Type: ApplicationFiled: April 25, 2002Publication date: December 11, 2003Applicant: A. Glenn BraswellInventor: Inna Yegorova
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Publication number: 20030203043Abstract: This invention provides compositions and methods related to the administration of deer antler, one or more nor-testosterone precursors, and one or more testosterone precursors, to increase testosterone levels, treat sexual dysfunction, improve sexual function, improve energy, enhance feelings of well-being and increase muscle mass in males. This invention also provides for inhibitors of the enzymes aromatase and/or 5-alpha reductase, to support testosterone levels and avoid undesirable metabolites.Type: ApplicationFiled: April 25, 2002Publication date: October 30, 2003Inventor: Inna Yegorova
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Publication number: 20030203047Abstract: This invention provides compositions and methods related to the administration of deer antler, one or more nor-testosterone precursors, and one or more testosterone precursors, to increase testosterone levels, treat sexual dysfunction, improve sexual function, improve energy, enhance feelings of well-being and increase muscle mass in males. This invention also provides for inhibitors of the enzymes aromatase and/or 5-alpha reductase, to support testosterone levels and avoid undesirable metabolites.Type: ApplicationFiled: April 25, 2002Publication date: October 30, 2003Applicant: A. Glenn BraswellInventor: Inna Yegorova
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Publication number: 20030086986Abstract: A number of discrete, isolated and well-characterized natural plant compounds show antimicrobial activity when used for topical applications in the ophthalmic, skin care, oral care, pharmaceutical, medical device, heath care products or similar preparations for topical application. Of particular interest are Allantoin, Berberine, Bilberry extract, Caffeic Acid Phenethyl Ether, Chlorogenic Acid, Cranberry Extract, Elderberry Extract, Ferulic Acid, Green Tea Extract, Grape Seed Extract, Hydroxytyrosol, Oleuropein, Olive Leaf Extract, Pine Bark Extract, Pomegranate Extract, Pycnogenol, Quercetin, Resveratrol, and Tart Cherry Extract. Oleuropein, and Pomegranate Extract, either alone or in combination, is extremely effective. Allantoin, can be used to enhance the efficacy of synthetic chemical disinfecting/preservative agents as well as to mitigate the cytotoxicity of some synthetic chemical disinfecting/preservative agents.Type: ApplicationFiled: April 4, 2002Publication date: May 8, 2003Inventors: Chris De Bruijn, F. Richard Christ, Anthony J. Dziabo, Joseph Vigh
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Patent number: 6555118Abstract: A pharmaceutical preparation for the treatment of wounds and ulcers in humans and animals and a method of preparation of the same are provided here. The composition consists of an alcoholic extract of Huangqin, Huanglian, Huangbai, Opuntia, Dilong, and &bgr;-sitosterol (from Soybean extract), in a vegetable oil-wax base, from where the alcohol is essentially removed by evaporation. The composition is used as a topical ointment for the treatment of wounds in its preferred embodiment. Wounds, in particular those occurring in the skin as second and third degree burns, stasis ulcers, trophic lesions, such as decubitus ulcers, diabetic ulcers, surgical wounds, severe cuts, diaper rash, cracked nipples and abrasions which are commonly resistant to the natural healing process, may be treated with this composition.Type: GrantFiled: February 22, 2001Date of Patent: April 29, 2003Inventor: Sarfaraz K Niazi
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Patent number: 6485734Abstract: A composition is provided which serves as a pediculicide for topical application to the hair and scalp of humans and other animals. The solutions take the form of a mousse, shampoo and a detergent. The active ingredient is a saponin, preferably derived from yucca extract.Type: GrantFiled: April 7, 1999Date of Patent: November 26, 2002Inventors: Bradley Baker, David Holland, Forrest Fesperman
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Patent number: 6447820Abstract: The disclosed is a treatment of existing and prevention of new skin scars in humans and animals using a topical application containing alcoholic extracts of Cortex Phellodendri and Opuntia ficus indica in a specific combination.Type: GrantFiled: January 22, 2001Date of Patent: September 10, 2002Inventor: Sarfaraz K Niazi
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Publication number: 20020102317Abstract: The invention concerns the field of biochemistry, and more precisely biological substances of vegetable origin. The invention concerns novel substances having non-cytotoxic biological activity, extracted from plants with CAM metabolism, such as plants of the Cactacees, Crassulacees and Saxifragacees family. The invention also concerns the method for obtaining these substances as well as compositions containing them. Said compositions are designed for accelerating and amplifying the synthesis of thermal shock proteins of cells of living beings in vivo or in vitro.Type: ApplicationFiled: January 25, 2002Publication date: August 1, 2002Applicant: INOVAT S.A.R.L.Inventors: Gilles Gutterrez, Mostafa Serrar, Lionel Viornery, James Norton
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Patent number: 6106853Abstract: Processes for controlling pollution by: (a) devolatizing vapor phase chemical pollutants (VP's) found in effluents and other bodies and streams of gases and liquids, and (b) stabilizing substrates from which the VP's are released. The offending VP's are converted to less offensive or inoffensive materials by interaction with an appropriately formulated treating agent (VTA/C) containing a primary halogen and at least one additional ingredient selected from the following classes of constituents (optional if bromine is the primary halogen and otherwise required): oligodynamically active metals, cohalogens, adjuncts, and facilitators. The major constituent(s) may be supplied as such, or a source of the constituent may be provided. Actinic radiation can be employed to promote reactions between the VP and the VTA/C, which is often formulated as an aqueous scrubbing medium.Type: GrantFiled: March 20, 1996Date of Patent: August 22, 2000Inventors: James P. Cox, Robert W. Duffy Cox
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Patent number: 6103681Abstract: A solid lavatory cleansing composition comprises phenyl ethyl alcohol of at least 2.5% by weight which acts as a fragrance and also as an antibacterial agent.Type: GrantFiled: June 4, 1999Date of Patent: August 15, 2000Assignee: Quest International B.V.Inventors: Stephen John Chantler, Paul Henry Dobson
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Patent number: 6093387Abstract: The present invention provides water-soluble, extended-release chemical formulations, in tablet form, for urine pretreatment, that require minimal, if any, use of a binder component, yet are non-dusting, pliable, structurally strong, and not weakened by exposure to aqueous streams. The present invention also provides a simple and reliable method for controlled dispensing of such tableted formulations into a liquid stream that is particularly advantageous for use in micro-gravity environments, such as spacecraft urinal systems.Type: GrantFiled: December 21, 1998Date of Patent: July 25, 2000Assignee: United Technologies CorporationInventors: Philip J. Birbara, Donald W. Rethke
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Patent number: 6077318Abstract: The present invention relates to an aqueous composition for reducing malodor impression. The composition comprises from about 0.01% to about 1%, by weight of the composition, of perfume wherein the perfume preferably comprises ingredients having a Clog P of 3 or smaller. Optionally, but preferably, the composition comprises from about 0.1% to about 5%, by weight of the composition of, water-soluble cyclodextrin, from about 0.1% to about 10%, by weight of the composition, of water-soluble metallic salt, from about 0% to about 3%, by weight of the composition, of solubilizing aid. The composition is essentially free of any material that would soil or stain fabric and contains less than about 5%, by weight of the composition of low molecular weight monohydric alcohols.Type: GrantFiled: July 22, 1997Date of Patent: June 20, 2000Assignee: The Procter & Gamble CompanyInventors: Toan Trinh, Jerome Paul Cappel, Philip Anthony Geis, Judith Ann Hollingshead, Mark Lee McCarty, Susan Schmaedecke Zwerdling
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Patent number: 6066293Abstract: A method for deodorizing toilets, and in particular the flushing fluid in a closed toilet system, comprises the use of phospholipids and 5-chloro-2-(2,4-dichlorophenoxy)phenol in the fluid to kill or inhibit odor-causing microbes.Type: GrantFiled: December 2, 1997Date of Patent: May 23, 2000Assignee: Chemia CorporationInventor: Norman A. Van Rees
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Patent number: 6015550Abstract: This invention concerns a method useful for reducing odor where odoriferous amine-containing compound is present, comprising: applying an alkylene carbonate to a source of the amine-containing compound under conditions such that the alkylene carbonate forms a reaction product with odoriferous amine-containing compounds such that odor is reduced. Sources of such amine-containing compounds include chicken coops, dumps, land fills, cat litter, stagnant water, water treatment ponds and plants, garbage cans and dumpsters, dog kennels, zoos, rendering plants food processing plants, slaughter houses, wool plants, fish canneries (cleaning and processing plants), underground sewers, paper mills, paper processing, outhouses and toilets that have no running water, and public restrooms.Type: GrantFiled: January 22, 1998Date of Patent: January 18, 2000Assignee: Huntsman Petrochemical CorporationInventor: Edward T. Marquis
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Patent number: 5984993Abstract: A method and composition are provided for controlling odor from waste products. The composition comprises a combination of chlorite salt and nitrate salt. The method includes the step of contacting the waste products or their surrounding airspace with the composition.Type: GrantFiled: March 20, 1998Date of Patent: November 16, 1999Assignee: Vulcan Materials CompanyInventors: Eric L. Mainz, David B. Griffith
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Patent number: 5897673Abstract: Fine metallic particles-containing fibers with various fine metallic particles therein, which have fiber properties to such degree that they can be processed and worked, and which can exhibit various functions of the fine metallic particles, such as antibacterial deodorizing and electroconductive properties are provided, as well as a method for producing the same.Type: GrantFiled: December 6, 1996Date of Patent: April 27, 1999Assignee: Japan Exlan Company LimitedInventors: Ryosuke Nishida, Yoko Yamamoto
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Patent number: 5882638Abstract: The present invention encompasses methods of controlling environmental malodors on human skin comprising the application to the skin of a composition comprising from about 0.1% to about 5%, by weight of the composition, of solubilized, water-soluble, uncomplexed cyclodextrin; and an aqueous carrier. The compositions can also comprise one or more of the following optional components: a linear dimethicone having a nominal viscosity of about 350 ecentistokes or less; low molecular weight polyols; water-soluble antimicrobial preservatives; zinc salts; water-soluble polymers; soluble carbonate and/or bicarbonate salts; chelating agents; zeolites; activated carbon; and mixtures thereof. The compositions can be applied directly as a spray, poured from a bottle and applied by hand, or applied via a wipe.Type: GrantFiled: October 15, 1997Date of Patent: March 16, 1999Assignee: The Proctor & Gamble CompanyInventors: Michael Thomas Dodd, Toan Trinh, Robert Gregory Bartolo, Juliet Marie Lucas, Robin Yager Buckner, Theresa Marie Kajs
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Patent number: 5879622Abstract: Scatalogical and other offensive odors are neutralized by prior deposit into a receptacle of drops of an alcoholic solution of menthol, peppermint oil and a pleasant smelling oil such as lemon oil. The menthol is present in an amount of 10% by weight, the lemon oil is present in an amount of 7.5% by weight, and the peppermint oil is present in an amount of 1% by weight.Type: GrantFiled: February 3, 1993Date of Patent: March 9, 1999Inventor: Frank Meehan
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Patent number: 5876707Abstract: The present invention provides water-soluble, extended-release chemical formulations, in tablet form, for urine pretreatment, that require minimal, if any, use of a binder component, yet are non-dusting, pliable, structurally strong, and not weakened by exposure to aqueous streams. The present invention also provides a simple and reliable method for controlled dispensing of such tableted formulations into a liquid stream that is particularly advantageous for use in micro-gravity environments, such as spacecraft urinal systems.Type: GrantFiled: April 29, 1997Date of Patent: March 2, 1999Assignee: United Technologies CorporationInventors: Philip J. Birbara, Donald W. Rethke
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Patent number: 5807587Abstract: A composition and method for preventing and/or reducing stench and septicity from animal waste comprising a sulfur and oxygen-bearing component and one or more aldehydes and/or one or more ketones. The sulfur and oxygen-bearing component is selected from the group consisting of sodium bisulfite, potassium bisulfite, lithium bisulfite, sodium metabisulfite, potassium metabisulfite, lithium metabisulfite, sodium hydrosulfite, potassium hydrosulfite, lithium hydrosulfite and hydrogen sulfite. The aldehyde is selected from the group consisting of formaldehyde, glyoxal, glutaraldehyde, benzaldehyde, acetaldehyde, butryaldehyde, cinnamaldehyde, anisaldehyde, salicylaldehyde, citral, glycolic aldehyde, paraldehyde, metaldehyde, heptylaldehyde, octylaldehyde and decylaldehyde. The ketone is selected from the group consisting of diacetyl, ionone, pseudo-ionone, acetylacetone, 3-buten-2-one, mesityl oxide, acetone, methyl ethyl ketone, diethyl ketone and dipropyl ketone.Type: GrantFiled: February 11, 1997Date of Patent: September 15, 1998Inventors: James P. Cox, Robert W. Duffy Cox
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Patent number: 5709872Abstract: A method for deodorizing toilets, and in particular the flushing fluid in a closed toilet system, comprises the use of phospholipids in the fluid to kill or inhibit odor-causing microbes.Type: GrantFiled: October 20, 1995Date of Patent: January 20, 1998Assignee: Chemia CorporationInventor: Norman A. Van Rees
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Patent number: 5660821Abstract: The present invention provides water-soluble, extended-release chemical formulations, in tablet form, for urine pretreatment, that require minimal, if any, use of a binder component, yet are non-dusting, pliable, structurally strong, and not weakened by exposure to aqueous streams. The present invention also provides a simple and reliable method for controlled dispensing of such tableted formulations into a liquid stream that is particularly advantageous for use in micro-gravity environments, such as spacecraft urinal systems.Type: GrantFiled: July 7, 1995Date of Patent: August 26, 1997Assignee: United Technologies CorporationInventors: Philip J. Birbara, Harold T. Couch, Joseph E. Genovese, Donald W. Rethke
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Patent number: 5543439Abstract: Described is a composition of matter particularly useful in fabricating toilet rim blocks consisting of:(a) extruded polyvinyl alcohol or partially hydrolyzed polyvinyl acetate with the maximum mole ratio of acetyl moiety:hydroxyl moiety being about 3:1 having a number average molecular weight of from about 15,000 up to about 68,000 containing 0 up to about 13% by weight of plasticizer;(b) from about 1 up to about 20% by weight of a compatible fragrance contained within the polyvinyl alcohol or partially hydrolyzed polyvinyl acetate;(c) from 0 up to about 20% by weight of a "foaming agent" which is a first surfactant and which can be a detergent, contained within the polyvinyl alcohol or partially hydrolyzed polyvinyl acetate;(d) from 0 up to about 20% by weight of a hydrophobic silica contained within the polyvinyl alcohol or partially hydrolyzed polyvinyl acetate;(e) from 0 up to about 20% by weight of at least one second surfactant in addition to the "foaming agent";(f) from 0 up to about 5% by weight of aType: GrantFiled: February 24, 1995Date of Patent: August 6, 1996Assignee: International Flavors & Fragrances Inc.Inventors: Keith J. McDermott, John M. Teffenhart, Shmuel D. Shefer, David A. Greene, Leslie C. Smith, Charles E. J. Beck
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Patent number: 5395625Abstract: A shape for chlorination and dechlorination tablets which reduces pillaring and wicking effects during fluid treatment and offers a consistent dissolution rate during the chlorination or dechlorination process. The opposing surfaces of the stacked tablets are formed by a combination of concave and convex shapes. The shape of the opposing surfaces prevents the formation of a central pillar, resulting in the formation of a side pillar instead. During the formation of the side pillar, the fluid contact surface area of the tablets gradually increases to compensate for the diminishing periphery of the tablets. As a result, the dissolution rate of the tablet is kept substantially constant over the course of tablet dissolution. The shape of the opposing surfaces of the stacked tablets also only provides for minimum contact between adjacent tablets, slowing the moisture diffusion speed and minimizing wicking effects.Type: GrantFiled: January 21, 1993Date of Patent: March 7, 1995Assignee: Jet, Inc.Inventor: Nianfa Tang
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Patent number: 5395585Abstract: The present method for deodorizing ammonia odor in an ammonia-containing environment includes adding to the environment a non-toxic, aqueous, acidified amine-based ammonia deodorizing composition in an amount effective to deodorize the ammonia odor in the environment. In addition, a method for preparing the ammonia deodorizing compositions and the compositions produced thereby is disclosed.Type: GrantFiled: January 19, 1993Date of Patent: March 7, 1995Assignee: Aquarium Pharmaceuticals, Inc.Inventor: Joel M. Goldstein
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Patent number: 5360574Abstract: This invention provides a deodorant composition in the form of gel containing chlorine dioxide, which comprises a gel product obtained by gelling an aqueous solution of stabilized chlorine dioxide with the use of both a polyethylene-imide having a molecular weight of from 10,000 to 100,000 and an epoxide crosslinking agent. The gel typed deodorant composition according to this invention is effective for deodorizing sulfur-containing compounds, has a high strength because of its solid gel form and a long-term stability, and is easy to handle including the time of exchanging the deodorant composition for another one.Type: GrantFiled: June 2, 1993Date of Patent: November 1, 1994Assignee: Aikoh Co., Ltd.Inventor: Takashi Iwahashi
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Patent number: 5330653Abstract: A method for the reduction of hydrogen sulfide in an enclosure which is involved in processing sewage and where workmen are present wherein methyl benzoate is used an additive to the sewage is described. The methyl benzoate is preferably in the form of a dilute aqueous emulsion. The emulsifier is preferably a polyoxyethylene derivative of a sorbitan fatty acid ester and most preferably, polyoxyethylene (20) sorbitan monolaurate.Type: GrantFiled: June 14, 1993Date of Patent: July 19, 1994Assignee: Zing Odor Control, Inc.Inventor: Albert L. Vroman
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Patent number: 5240699Abstract: A deodorant consisting of deodorizing ingredients respectively extracted from plants and capable of performing deodorization with respect to a relatively wide range of odors, and performing as a whole the deodorization over a relatively wide range covering one or both sulfur and nitrogen compound odors. The plants are selected from a group consisting of Osmanthus, Forsythia, Paulownia, Syringa, Fartugium, Petasites, Loropetalum, Houttuynia, and Oxaslis.Type: GrantFiled: November 9, 1989Date of Patent: August 31, 1993Assignee: Matsushita Electric Works, Ltd.Inventors: Koji Osada, Haruyuki Date, Yasuhiro Saihara, Toshiyuki Yamauchi, Shiro Koike
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Patent number: 5137687Abstract: This invention relates to a process for reducing odor perceived by a nearby community from an odor-emitting system, e.g., sewage treatment, etc., by adsorbing on core particles, as described, condensible components present in the system. The malodorous components then cannot adsorb in a film of condensible components on the aerosol to be carried by the aerosol plume into the surrounding community, but remain with the humid gas plume to be dispersed upward into the atmosphere. The process is useful for any system which contains condensible components and malodorous components and whose emissions form aerosols.Type: GrantFiled: August 19, 1991Date of Patent: August 11, 1992Assignee: E. I. du Pont de Nemours and CompanyInventor: James B. Dunson, Jr.
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Patent number: 5110586Abstract: A white colored deodorizer comprising zinc oxide and at least one oxide selected from the group consisting of aluminium oxide and silicon oxide and a method for preparation of it are disclosed.Type: GrantFiled: June 21, 1990Date of Patent: May 5, 1992Assignee: Titan Kogyo Kabushiki KaishaInventors: Tokumitsu Kurihara, Tatsuo Saito, Hidefumi Harada
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Patent number: 5108739Abstract: A white colored deodorizer comprising titanium oxide and zinc oxide and a method for its preparation are disclosed.Type: GrantFiled: June 21, 1990Date of Patent: April 28, 1992Assignee: Titan Kogyo Kabushiki KaishaInventors: Tokumitsu Kurihara, Tatsuo Saito, Hidefumi Harada
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Patent number: 5078992Abstract: Disclosed herein are a water-absorbing resin composition composed of a water-absorbing resin and a metallophthalocyanine, and a method for utilizing the water-absorbing resin composition as a deodorant in the presence of water.Type: GrantFiled: March 6, 1990Date of Patent: January 7, 1992Assignees: Ahsu Kurin Kabushiki Kaisha, Nisshin Seifun Kabushiki Kaisha, Nippon Shokubai Co., Ltd.Inventors: Yoshiyuki Takahashi, Tadao Shimomura, Naoyuki Shirane
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Patent number: 5071622Abstract: This invention relates to a process for reducing odor perceived by a nearby community from an odor-emitting system, e.g., sewage treatment, etc., by adsorbing on core particles, as described, condensible components present in the system. The malodorous components then cannot adsorb in a film of condensible components on the aerosol to be carried by the aerosol plume into the surrounding community, but remain with the humid gas plume to be dispersed upward into the atmosphere. The process is useful for any system which contains condensible components and malodorous components and whose emissions form aerosols.Type: GrantFiled: September 15, 1989Date of Patent: December 10, 1991Assignee: E. I. Du Pont de Nemours and CompanyInventor: James B. Dunson, Jr.
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Patent number: 5009887Abstract: A new deodorant composition in the form of gel is now provided, which comprises 2% to 30% by weight of sodium polyacrylate or ammonium polyacrylate having a molecular weight of form 40,000 to 300,000, 1% to 10% by weight of diglycidyl ether or polyglycidyl ether, 5% to 40% by weight of deodorizer containing as active ingredients ethanaminium N-(carboxymethyl)-2-hydroxy-N, N-bis(2-hydroxyethyl)choride, diethanolamine, triethanolamine and glyoxal, and the remainder of water.The gel typed deodorant composition according to this invention may effectively be used to deodorize acidic and alkaline bad odors in the enclosed areas.Type: GrantFiled: July 31, 1989Date of Patent: April 23, 1991Assignee: Aikoh Co., Ltd.Inventor: Takashi Iwahashi
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Patent number: 4994266Abstract: A toilet rinse block is free of para-dichlorobenzene and includes a fragrance alcohol in the form of a metal complex (e.g., citronellol aluminate) that releases the fragrance upon rinsing with water.Type: GrantFiled: July 7, 1989Date of Patent: February 19, 1991Assignee: Bush Boake Allen LimitedInventor: Brian L. Wells
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Patent number: 4968496Abstract: Disclosed are deodorants containing the hydrolyzed ene-adducts and Diels-Alder adducts of ricinene fatty acids and maleic anhydride, which preferably additionally contain(a) zinc ricinoleate with zinc compounds of multiply hydroxylated higher fatty acids, oxamines and resin acids and(b) solvents taken from the group of alcohols, optionally with the addition of water, triethanolamine and organic acids.Type: GrantFiled: July 14, 1988Date of Patent: November 6, 1990Assignee: Grillo-Werke AGInventors: Dieter Rohe, Peter Bubel, Klaus Driemel
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Patent number: 4959207Abstract: A deodorant composition comprising (A) a compound having an acid anhydride group in a molecule and (B) a copper compound, said deodorant composition being useful as a deodorant composite material comprising a substrate (such as a paper, a fabric, a foamed sheet, a pulp, fibers or an inorganic substance) and the deodorant composition included therein, a deodorant resin composition composed of a thermoplastic resin and the deodorant composition, or a shaped article produced by processing the deodorant resin composition.Type: GrantFiled: March 2, 1988Date of Patent: September 25, 1990Assignee: Nippon Zeon Co., Ltd.Inventors: Tsunehisa Ueda, Kouji Miyazaki, Tadao Natsuume, Yoshiaki Miki
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Patent number: 4919925Abstract: A deodorant comprising a Diels-Alder reaction-type adduct of an alpha,beta-unsaturated dicarboxylic acid anhydride and an olefin or a derivative of the adduct as an active ingredient. A composite material, a resin composition, a resin article and a foam each containing the deodorant.Type: GrantFiled: July 13, 1988Date of Patent: April 24, 1990Assignee: Nippon Zeon Co., Ltd.Inventors: Tsunehisa Ueda, Kouji Miyazaki, Tadao Natsuume