Containing Or Obtained From A Fruit (aka Fructus), Including Berry Patents (Class 424/777)
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Publication number: 20030031740Abstract: The present invention relates to processes for the treatment of liquors derived from oil-bearing fruit, for example from oil palm fruit, and to products therefrom. Typically a process involves removal of undissolved solids, oleaginous parts, colloids and higher weight molecules from the vegetation liquor to give an aqueous fraction containing phytochemicals, for example, flavonoids, phenolic acids and hydroxy acids. Subsequently, pH adjustment and solvent extraction upon said aqueous fraction realise an extract rich in hydroxy acids or phenolic acids or flavonoids or any combination thereof Applications of the substances subject of this invention are to be found in drinks, edible products, tonics, health supplements, antioxidant additives, cosmetics, soaps, shampoos, detergents, drugs or medicinal products.Type: ApplicationFiled: October 11, 2002Publication date: February 13, 2003Inventors: Ravigadevi Sambanthamurthi, Yew Ai Tan, Kalyana Sundram
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Publication number: 20030017217Abstract: Procedure for obtaining Olea Europea extracts from Olea Europea leaves dried at less than 35° C.Type: ApplicationFiled: March 8, 2002Publication date: January 23, 2003Inventors: Eliseo Quintanilla Almagro, Gines Aviles Olmos, Jose Antonio Tovar Oliva, Joaquin Diaz Alperi, Jose Sempere Ortells, Jose Pardo Zapata
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Patent number: 6506395Abstract: The present invention is directed to a wildlife attractant comprised of an extract from the fruit of the hedge apple tree and methods for using the attractant to attract deer and cover the scent of a human user.Type: GrantFiled: March 16, 2001Date of Patent: January 14, 2003Inventor: James Lillig
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Patent number: 6506421Abstract: The present invention is a process for the extraction of an active principle for action against the consequences of oxidative stress, permitting countering cutaneous aging, characterized in that it comprises the following steps: reduction to fine powder of dried apple tegument, solubilization of this powder with at least 8% by volume of powder in an aqueous solution, conjoint enzymatic hydrolysis of the sugars and proteins, heating permitting total inactivation of the enzymes, and sterilizing filtration to retain the microorganisms, yeasts and molds as well as the total mesophilic flora. The invention also covers the associated compositions and a process for countering accelerated aging of the skin.Type: GrantFiled: May 4, 2001Date of Patent: January 14, 2003Assignee: Societe Industrielle Limousine d'Application Biologique (Silab)Inventor: Jean-Jacques Paufique
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Patent number: 6503505Abstract: The present invention discloses: (i) a non-pathogenic probiotic microorganism and its probiotic/therapeutic uses; (ii) a formulation comprising an aqueous solution of a volatile fraction (VF) prepared from the extract of at least one plant derived material and its therapeutic uses; (iii) a process of manufacturing the formulation from the plant derived material; (iv) a probiotic composition comprising the non-pathogenic probiotic microorganism of the invention and/or other probiotic microorganism(s) and the formulation of the invention, and its probiotic/therapeutic uses; (v) a composition for industrial applications comprising the formulation of the invention and microorganism(s) of industrial applicability; and (vi) industrial processes and apparatuses in which the latter composition is used.Type: GrantFiled: November 13, 2001Date of Patent: January 7, 2003Assignee: The Bio Balance CorporationInventors: Mark Olshenitsky, Genadi Buchman
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Patent number: 6500467Abstract: The present invention discloses: (i) a non-pathogenic probiotic microorganism and its probiotic/therapeutic uses; (ii) a formulation comprising an. aqueous solution of a volatile fraction (VF) prepared from the extract of at least one plant derived material and its therapeutic uses; (iii) a process of manufacturing the formulation from the plant derived material; (iv) a probiotic composition comprising the non-pathogenic probiotic microorganism of the invention and/or other probiotic microorganism(s) and the formulation of the invention, and its probiotic/therapeutic uses; (v) a composition for industrial applications comprising the formulation of the invention and microorganism(s) of industrial applicability; and (vi) industrial processes and apparatuses in which the latter composition is used.Type: GrantFiled: November 13, 2001Date of Patent: December 31, 2002Assignee: The Bio Balance CorporationInventors: Mark Olshenitsky, Genadi Buchman
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Publication number: 20020197303Abstract: The present invention relates to a crude drug patch, and in particular to a crude drug patch which is fabricated using a gardenia having a certain function such as an antimicrobial function, a suppression and fever removing function. A homeostasis function, etc., a raw rehmannia glutinose is capable of softening a coagulated blood, mitigating a blood stasis, and curing a wound. In addition, it is possible to mitigate a pain by sticking on a diseased part such as a labor pain/anti-inflammation, sprain, bruise, muscle pain, joint pain, lumbago, shoulder pain, neuralgia, rheumatic pain, etc. based on a combined prescription of a fermented soybean paste (toenjang), wheat flour and green tea at a certain ratio. Even when a crude drug patch according to the present invention is stuck on a skin using a natural material as an effective component, there is not any side effect.Type: ApplicationFiled: May 22, 2002Publication date: December 26, 2002Inventor: Ki Hong Kim
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Publication number: 20020197219Abstract: The present invention relates to compositions containing a peptide(s) and a pigment(s) and the use of such peptides or such compositions in darkening the skin.Type: ApplicationFiled: May 21, 2001Publication date: December 26, 2002Inventors: Miri Seiberg, Stanley S. Shapiro
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Patent number: 6495174Abstract: Described here a composition comprising of alcoholic extracts of herbs RHIZOMA ZINGIBERIS RECENS, RHIZOMA PINELLIAE, FLOS CARTHAMI, RADIX REHMANNIAE, RADIX ANGELICAE SINESIS, RADIX PAENOIAE RUBRA, CACUMEN BIOTAE, SEMEN SESAMI NIGRUM, RADIX POLYGONI MULTIFLORI, FRUCTUS MORI combined with TINCTURE CAPSICUM, TINCTURE CANTHARIDINATE, and OLEUM RICINI for direct application to scalp for the treatment of all kinds of alopecia in humans. Alternately, the herbs listed here can be used individually.Type: GrantFiled: February 21, 2001Date of Patent: December 17, 2002Inventor: Sarfaraz K. Niazi
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Publication number: 20020187208Abstract: An extract from the Melothria Indica Lou plant, which has the effect of inhibiting the release of cytokines, including Tumor Necrosis Factor-alpha, by immune response cells, such as macrophages, for the therapeutic treatment of sepsis.Type: ApplicationFiled: March 4, 2002Publication date: December 12, 2002Applicant: Ambryx Biotechnology, Inc.Inventor: David M. Tsai
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Publication number: 20020176903Abstract: The present invention relates to an external agent for the skin comprising an extract prepared from olive plants and also relates to an external agent for the skin comprising the extract as a skin-beautifying component, in particular, as an ant-aging component for the skin and/or a whitening component. The extract can be prepared by extracting olive plants and/or products generated during and after the olive oil-manufacturing processes with water and/or an organic solvent and further the extract can further be subjected to a concentration treatment and/or a fractionation-purification treatment to thus improve each effect.Type: ApplicationFiled: April 3, 2002Publication date: November 28, 2002Inventors: Noriyasu Kuno, Miho Matsumoto
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Publication number: 20020168426Abstract: The invention provides a new formulation of the composition comprising Flos Lonicerae Fructus Forsythiae and Radix Scutellariae. This invention also provides a method for identification with HPLC and the characteristic peaks of the compositions of said composition. The composition possesses antiviral effective, namely, inhibition of influenza virus, parainfluenza virus, herpes I virus and herpes II virus. The invention refers to a method for preparation and control of the active components of Flos Lonicerae Fructus Forsythiae and Radix Scutellariae for its biological activity. The invention also provides a unique raw materials and intermediate formulation.Type: ApplicationFiled: October 24, 2001Publication date: November 14, 2002Inventors: Ping Niang Shen, Ke Feng Ruan, Yu Lan Wang, Wei Yu, Wen Oing Zhang, Xiao Kun Hong, Xin Hong Wang
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Patent number: 6479081Abstract: The invention concerns a method for obtaining grape pomace and/or seed tannin, comprising steps which consist in: (a) from fresh black or white grapes pomace and/or seed, carrying out a solid-liquid extraction of raw tannin fraction in an aqueous solvent; (b) eliminating the first solvent from the resulting extract to obtain a concentrate of the raw tannin fraction; and (c) purifying the raw tannin fraction to obtain said tannin: The method is characterised in that in step (a) sulphite water (H2O+SO2) is used as solvent, and in step (c) the raw tannin fraction is purified by selectively adsorbing the tannin polyphenol compounds on resin and by subsequent filtering. The invention also concerns the resulting tannin and its uses in particular as endogenous tannin in wine.Type: GrantFiled: September 20, 2000Date of Patent: November 12, 2002Assignee: FercoInventor: Marc Feries
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Patent number: 6461648Abstract: Process for purifying a red fruit extract containing anthocyanosides, according to which: said extract is taken up in an aqueous solution; the aqueous extract is cooled until it reaches a homogeneous temperature of less than 15° C.; after filtering the aqueous extract, the permeate obtained is recovered and loaded onto a macrocrosslinked polymeric resin; the resin is then rinsed with demineralized water; then the resin obtained is eluted with an alcoholic eluting solution; finally, the eluate obtained is concentrated and then dried.Type: GrantFiled: August 14, 2001Date of Patent: October 8, 2002Assignee: Ferlux (Societe Anonyme)Inventors: Chrystèle Soulier, Dominique DuFour
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Patent number: 6455078Abstract: The present invention provides a herbal pharmaceutical composition for treating patients with liver diseases and/or HIV. The composition contains fifteen (15) ingredients, which are diffuse hedyotis, bistort rhizome, giant knotweed rhizome, Asiatic moonseed rhizome, baical skullcap root, bovine biliary powder, milkvetch root, barbary wolfberry fruit, sanqi, red ginseng, figwort root, Chinese magnoliavine fruit, turmeric root-tuber, hawthorn fruit, and Chinese angelica. Among the fifteen (15) ingredients, diffuse hedyotis, bistort rhizome, giant knotweed rhizome, and Chinese magnoliavine fruit are the required herbs which contribute to the efficacy of the pharmaceutical composition.Type: GrantFiled: July 18, 2001Date of Patent: September 24, 2002Inventor: Tzu-Sheng Wu
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Patent number: 6444236Abstract: A composition is provided for use in health foods for promoting the circulation of blood, prepared from medicinal herbs, including Lycium chinense Miller, Agastache rugosa (Fischer et Meyer) O. Kuntze, Pueraria lobat Ohwi, Macrocarpium officinale Sieb. et Zucc., Gastrodia elata blume, Amomum xanthioides Wallich, Cratagegus pinnatifida Bge., Aquillaria Agallocha Roxburgh, Inula Helenium L., Cassia obtusifolia L., and Rubus sachalinensis Lev., and young antlers of Cornu cervi. In addition to being safe to the body, the composition exhibits excellent pharmaceutical effects of treating arteriosclerosis and alleviating the headache attributed to the disturbance of blood circulation.Type: GrantFiled: August 27, 2001Date of Patent: September 3, 2002Inventor: Wan-Seok Han
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Patent number: 6440467Abstract: Disclosed is a method of producing a reconstituted fruit, herb, and/or seed fiber product, the product produced using the method, and dietary supplements containing the product. The steps used to produce the product include expressing juice from a fruit, herb, or seed; concentrating the juice by removing water; infusing pomace obtained during expression of the juice with the concentrated juice, and drying the steeped pomace to obtain a dry, non-hygroscopic, free-flowing nutritional supplement.Type: GrantFiled: February 20, 2001Date of Patent: August 27, 2002Inventor: Douglas G. Mann
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Patent number: 6436449Abstract: Use of an extract derived from the fruits, leaves, the bark or the roots of Morinda citrifolia L. for the manufacture of a medicament for the treatment of a mammal suffering from tinnitus. The extract may be a liquid present in the medicament in an amount such as to give a daily dosage of 0.1-2 ml, or 0.2-1 ml, e.g. 0.4-0.7 ml, per kg body weight of the patient. The extract also may be a solid present in the medicament in an amount such as to give a daily dosage of 5-200 mg, or 10-100 mg, e.g. 20-70 mg, per kg body weight of the patient. Optionally, the medicament also may comprise lycopene, vitamine C, coenzyme Q10 and an extract from the leaves of Ginkgo biloba. The medicament may be given e.g. by oral, rectal, transdermal or inhalation administration.Type: GrantFiled: March 2, 2001Date of Patent: August 20, 2002Inventor: Bo Gidlund
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Patent number: 6428822Abstract: A mixed substance for treating hypertension, constipation, detoxification, boost immune system produced by extracting arctium lappa L., carrot, and whole radish with water one or two hours at temperature 70° C. 100° C. under agitating, separated the extracts and solid by-products, vacuum condensed the extracts, then at low temperature lyophilized condensed extracts to powder, encapsulated powder or pressed powder to tablet. Patient taking a daily dosage of this vegetable medicine have shown greatly improved healthy condition.Type: GrantFiled: April 3, 2001Date of Patent: August 6, 2002Assignee: Chengzhi Life Science Company, Ltd.Inventors: Yuan Shi, Yongsen Yang, Dong Xu
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Patent number: 6428825Abstract: The present invention relates to an herbal therapeutic product for controlling diabetes mellitus comprising at least one hypoglycemic compound extracted from the pulp of fruit Eugenia jambolana. The process for the preparation of the herbal therapeutic product to control the glucose level, comprises cleaning and drying the fruit of a species of family Eugenia to remove extraneous material from the outermost layer of the said fruit. De-seeding the fruit and soaking the said de-seeded fruit in water under controlled cooled conditions overnight to retain the activity of hypoglycemic compounds in the mixture of water and pulp of de-seeded fruit. It is followed by mixing the mixture to achieve a uniform consistency.Type: GrantFiled: February 5, 2001Date of Patent: August 6, 2002Assignee: Indian Council of Medical ResearchInventors: Suman Bala Sharma, Pothapragada Suryanarayana Murthy, Krishan Madhav Prabhu, Afreena Nasir
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Publication number: 20020102317Abstract: The invention concerns the field of biochemistry, and more precisely biological substances of vegetable origin. The invention concerns novel substances having non-cytotoxic biological activity, extracted from plants with CAM metabolism, such as plants of the Cactacees, Crassulacees and Saxifragacees family. The invention also concerns the method for obtaining these substances as well as compositions containing them. Said compositions are designed for accelerating and amplifying the synthesis of thermal shock proteins of cells of living beings in vivo or in vitro.Type: ApplicationFiled: January 25, 2002Publication date: August 1, 2002Applicant: INOVAT S.A.R.L.Inventors: Gilles Gutterrez, Mostafa Serrar, Lionel Viornery, James Norton
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Patent number: 6426098Abstract: Compositions for treating hepatic disorders via oral or parenteral administration include Salvia miltiorrhiza and Polyporus umbellatus in proportions of about 1:1 to about 5:1, and may comprise from about 6% to about 30% of the total weight of the composition which may also include other herbs such as Curcuma longa, Astragalus membranaceus, Loranthus parasiticus and Polygonum cuspidatum.Type: GrantFiled: October 3, 2000Date of Patent: July 30, 2002Assignee: Cathay Herbal LaboratoriesInventor: Yi Fan Yang Jr.
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Publication number: 20020076451Abstract: An object of the present invention is to provide a very effective health food exhibiting the effect near that which has been already achieved by the traditional Chinese medical science. The present invention relates to a health food product comprising cholic acid, especially to a health food product comprising cholic acid and isoflavone and/or isoflavone glycoside.Type: ApplicationFiled: April 10, 2001Publication date: June 20, 2002Applicant: DAICHO KIKAKU INCORPORATED COMPANYInventor: Takao Daicho
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Patent number: 6403086Abstract: Compositions and methods are provided for reducing oxysterol buildup in the blood and normalizing cholesterol and blood pressure, in a mammal. The compositions comprise Morinda citrifolia extract, red wine extract, prune extract, blueberry extract, pomegranate extract, apple extract, and an enzyme mixture.Type: GrantFiled: November 30, 2001Date of Patent: June 11, 2002Inventor: Inna Yegorova
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Patent number: 6403125Abstract: The utilization of at least one extract of a plant belonging to the cecropia genus as an active agent. The extract is used alone or in conjunction with at least one other active agent for preparing a cosmetic or dermopharmaceutical product or a cosmetic or dermopharmaceutical composition for external local application on the skin, the mucous membranes and/or the epithelial or body appendage formations.Type: GrantFiled: June 21, 2001Date of Patent: June 11, 2002Assignee: Cognis France (Societe Anonyme)Inventors: Gilles Pauly, Christian Moretti
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Publication number: 20020068100Abstract: Disclosed is a composition comprising ingredients a-f: a) n-6 fatty acid; b) n-3 fatty acid; c) vitamin E; d) extract of Viburnum opulus bark; e) extract of Vitex agnus castus berry; and f) bioflavonoid(s). Also disclosed is a method of treating premenstrual symptoms in a subject in need of such treatment and a method of treating irritable bowel syndrome or interstitial cystitis in a subject in need of such treatment. The method comprises the step of administering to the subject a therapeutically effective amount of the ingredients a-f, described above. Preferably, the subject is administered a composition comprising ingredients a-f.Type: ApplicationFiled: October 11, 2001Publication date: June 6, 2002Applicant: Bioriginal Food & Science CorporationInventors: Rakesh Kapoor, Alessandra Berruti
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Publication number: 20020068102Abstract: Providing and using a dietary supplement to reduce cellular damage within the human body. The dietary supplement includes reconstituted Morinda citrifolia fruit juice from pure juice puree of French Polynesia, and may include other natural juices, such as a natural grape juice concentrate, a natural blueberry juice concentrate, and/or another natural juice concentrate. The dietary supplement includes a combination of compounds that work at the cellular level to increase the positive functionality of cells in the body, including cell regeneration and cell function, to increase the ability of cells to absorb and utilize nutrients, such as vitamins and minerals, and to. Furthermore, the dietary supplement scavenges lipid hydroperoxides and superoxide anion free radicals within the body to reduce cellular damage.Type: ApplicationFiled: November 29, 2001Publication date: June 6, 2002Inventors: Chen Xing Su, Claude Jarakae Jensen, Stephen P. Story
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Patent number: 6399112Abstract: This application relates to a material which is suitable for the treatment of atopic disease, non-atopic eczema or psoriasis. The material can be extracted from a freeze-dried decoction of a mixture comprising the following Chinese herbs: Radix Ledebouriella, Fructus Tribuli, Herba Potentilla chinensis, Caulis Clematis armandii, Radix Rehmannia, Radix Glycyrrhiza, Radix Paeonia rubra, Cortex Dictamni radicis, Herba Lopatheri, Spica Schizonepetae. The material comprises one or more of those components present in the freeze-dried decoction which run with Rf values in the ranges 0.00 to 0.100, 0.167 to 0.300, 0.400 to 0.533, 0.700 to 0.833 or 0.900 to 0.967 if the freeze-dried decoction is diluted in aqueous solution and subjected to chromatography on a Whatman 2 cms×55 cms×3 mm cellulose strip for 10 hours using a solvent mixture of butanol, ethanol and water in the proportions 4:1:1.Type: GrantFiled: December 24, 1996Date of Patent: June 4, 2002Assignee: Phytotech LimitedInventors: Brian Anthony Whittle, Jonathan Brostoff, Yvette Latchman
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Publication number: 20020064567Abstract: Antiviral and antifungal compositions comprise a ferrous salt and a plant extract of pomegranate rind, Viburnum plicatum leaves or flowers, tea leaves or maple leaves in aqueous solution.Type: ApplicationFiled: October 11, 2001Publication date: May 30, 2002Inventors: Sabah Abdel Amir Jassim, Stephen Paul Denyer, Gordon Sydney Anderson Birnie Stewart
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Patent number: 6395280Abstract: An oral deodorant for excreta containing a proanthocyanidin as an active ingredient and a method of reducing the odor of excreta of an object comprising dosing the object with an effective amount of a proanthocyanidin.Type: GrantFiled: July 27, 2000Date of Patent: May 28, 2002Assignee: Kikkoman CorporationInventors: Jun Yamakoshi, Shigehiro Kataoka, Hiroshi Hosoyama, Toshiaki Ariga
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Patent number: 6395310Abstract: A composition used to treat diabetes is disclosed. The composition is made by first, mixing an isolated embryo bud and isolated seed coat from rice with a fruit body of Ganoderma lucidum to form a mixture. Next, the mixture is fermented with an Aspergillus oryzae strain to produce a resulting fermentate. Then, the resulting fermentate is dried to produce a dried fermentate. Next, the dried fermentate is crushed into a fine powder and lastly, the powder is mixed with vitamin B to form the composition.Type: GrantFiled: October 18, 2001Date of Patent: May 28, 2002Assignee: Kabushiki Kaisha Genmai KosoInventor: Teruaki Iwasaki
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Patent number: 6391854Abstract: A water soluble extract of M.charantia named MC6, methods for its preparation and methods for its use in the treatment of hyperglycemic disorders are provided. The active MC6 is characterized by moving as a single band on SDS-PAGE having a molecular weight of less than 10 kDal, and by comprising tree peptides. Also provided is a peptide component of MC6 named MC6.1, as well as analogues and mimetics thereof. The active MC6, MC6.1, MC6.2, and MC6.3 exhibit hypoglycemic activity, even following oral administration. Also provided are methods of using the active agents to treat hyperglycemic disorders, particularly diabetes, where the active agents are preferably orally administered.Type: GrantFiled: July 31, 2000Date of Patent: May 21, 2002Assignee: Calyx Therapeutics, Inc.Inventors: Bishwajit Nag, Satyanarayana Medicherla, Somesh D. Sharma
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Publication number: 20020058078Abstract: The invention provides olive-derived hydroxytyrosol. According to one aspect of the invention, vegetation water is collected from olives. Acid is added to stabilize the vegetation water and prevent fermentation. The mixture is incubated to allow oleoeuropein to convert to hydroxytyrosol, and then fractionated to separate hydroxytyrosol from other components. The hydroxytyrosol is useful as a natural anti-bacterial, anti-viral and fungicidal product for agricultural and pest control applications. In addition, it is useful as a therapeutic and anti-oxidant for a variety of health purposes.Type: ApplicationFiled: August 31, 2001Publication date: May 16, 2002Inventor: Roberto Crea
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Patent number: 6387370Abstract: Compositions and methods are provided for reducing oxysterol buildup in the blood and normalizing cholesterol and blood pressure, in a mammal. The compositions comprise Morinda citrifolia extract, red wine extract, prune extract, blueberry extract, pomegranate extract, apple extract, and an enzyme mixture.Type: GrantFiled: January 19, 2001Date of Patent: May 14, 2002Inventor: Inna Yegorova
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Patent number: 6387416Abstract: An orally or topically administered composition capable of reducing inflammation in animals, preferably humans, suffering from inflammation, contains a therapeutically effective amount of a post-supercritical carbon dioxide alcoholic extract of ginger; therapeutically effective amounts of supercritical carbon dioxide extracts of rosemary, turmeric, oregano and ginger (preferably certified organic ginger); and therapeutically effective amounts of hydroalcoholic extracts of holy basil, turmeric, scutellariae baicalensis, rosemary, green tea, huzhang, Chinese goldthread, and barberry. The composition is preferably orally administered on a daily basis for at least about 4 weeks.Type: GrantFiled: April 5, 2001Date of Patent: May 14, 2002Inventors: Thomas Newmark, Paul Schulick
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Publication number: 20020054920Abstract: The present invention provides antistress compositions contaning various medicinal herbs which are composed of one or more of medicinal herb 2.0˜40.0 g of fructus hordel germintus, messa medicata fermentata, frucutus amomi and fructus crataegei; hone or more of medicinal herb 2.0˜40.0 g of radix polygalae, semen zizyphi spinosae and rhizoma acori graminei; one or more of medicinal herb 2.0˜40.0 g selected from the group of poria holen and poria, one or more of medicinal herb 2.0˜40.0 g of folium phyllostachyos, calus in taein phyllostachos, succus phyllostachos and radix scutellariae; one or more of medicinal herb 2.0˜40.0 g of legumonosae, fructus amomicardamomi, semen glycine and semen lablab; one or more of medicinal herb 2.0˜40.0 g of rhizoma zingiberis, radix asari, rhizoma zingiberis siccatum and radix aconiti; one or more of medicinal herb 2.0˜40.0 g of bulbos allii fistulosi, herba ephedrae and folium perillae; and one or more of medicinal herb 2.0˜40.Type: ApplicationFiled: December 6, 2000Publication date: May 9, 2002Applicant: Byung Hag ChoiInventors: Byung Hak Choi, Gyung Mi Park
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Patent number: 6372220Abstract: The present invention to a material that is coated with or soaked in a suspension of a botanical extract such that particles of said natural botanical extract are in contact with, embedded on, or embedded within the material. The present invention can be used to preserve perishable substances such as edible substances or foods by extending their freshness, shelf life or suitability for consumption by living organisms. Botanical extracts suitable for the present invention include botanical extracts that have anti-bacterial, anti-fungal, anti-viral or other preventative or curative properties. The botanical extract coated material described in the present invention is suitable for applications such as the packaging and preservation of perishable substances such as fruits and vegetables, meat products, dairy products, edible substances, non-edible substances and other perishable substances. Specifically, the material is impregnated with an extract of Fenugreek (Trigonella foenum-graecum).Type: GrantFiled: February 5, 2001Date of Patent: April 16, 2002Inventor: Kavita Shukla
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Cancer cell growth suppressor and cell differentiation inducer and method for manufacturing the same
Publication number: 20020039601Abstract: A cancer cell growth suppressor or a cell differentiation inducer is provided which contains as an effective component a water-soluble component of Capsicum Annuum L.Var.grossumn which is a Solanacede plant. It is manufactured by mixing dried powder of fruits of Capsicum Annuum L.Var.grossumn and water for 40 hours or longer while maintaining them at normal temperature or higher, and obtaining an aqueous solution or a water-soluble component by separating the mixture into solid and liquid. A component having cancer cell growth suppressing properties or cell differentiation inducting properties, which could not be extracted sufficiently in a normal, short-time water-soluble component-extracting step, is reliably contained. It is used as a cancer cell growth suppressor or a cell differentiation inducer for treating cancer carriers or preventing recurrence.Type: ApplicationFiled: October 4, 2001Publication date: April 4, 2002Inventor: Takeshi Mori -
Patent number: 6361804Abstract: The present invention relates to cosmetic formulations for topical application containing extracts from Phyllanthus emblica and Centella asiatica and/or Bacopa monnieri, and the use of such formulations for the care of the human skin. In particular, the present invention relates to cosmetic formulations for topical application containing extracts from Phyllanthus emblica and Centella asiatica and/or Bacopa monnieri in addition to per se known adjuvants and expedients.Type: GrantFiled: March 30, 2001Date of Patent: March 26, 2002Inventor: Shyam B. Singh-Verma
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Patent number: 6358542Abstract: The present invention provides methods of extracting antioxidant compositions from olive-based starting materials, including olives, olive pulps, olive oil, and wastewater from olive oil manufacturing. One method includes the steps of extracting the olives, olive pulp or olive oil with a polar aqueous solvent to form an aqueous phase containing antioxidant components, passing the aqueous phase through a solid matrix to trap the antioxidant components on the matrix, and washing the matrix with a polar organic solvent to yield a solution of the antioxidant composition in the polar organic solvent. Another method includes the steps passing the wastewater from olive oil production containing antioxidant components through a solid matrix to trap the antioxidant components on the matrix, and washing the matrix with a polar organic solvent to yield a solution of the antioxidant composition in the polar organic solvent.Type: GrantFiled: December 20, 1999Date of Patent: March 19, 2002Assignee: Usana, Inc.Inventors: John Cuomo, Alexandre B. Rabovskiy
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Patent number: 6358540Abstract: A method for treating tinnitus comprising the step of administering to a subject requiring such treatment a therapeutically effective amount of an herbal composition comprising Radix Puerariae, Radix Platycodi Grandiflori, Radix Angelicae Dahuricae, Semen Coicis Lachryma-jobi, Rhizoma Zigiberis Officinalis Recens, Radix Ligustici Chuanxiong, Radix Paeoniae Lactiflorae, Folium Perillae Frutescentis, Flos Magnoliae, Herba cum Radice Asari, Ramulus Cinnamomi Cassiae, Radix Scutellariae Baicalensis, and Radix Glycyrrhizae Uralensis.Type: GrantFiled: November 7, 2000Date of Patent: March 19, 2002Inventors: Stanley T. Ozog, III, Delmar S. Neville, II
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Patent number: 6355280Abstract: A composition for reducing cell apoptosis is disclosed. The composition contains from about 0.01% to about 0.15% of a mixture of avacado lipid unsaponifiables and soybean lipid unsaponifiables which protects against the apoptotic effect of phorbol myristyl acetate (PMA). The composition also prevents the inhibition of cellular aging and for protection of the skin against negative environmental factors and pollutants.Type: GrantFiled: February 28, 2000Date of Patent: March 12, 2002Assignees: I.M.S. CosmeticsInventors: Joseph Segal, Michael Schlosser, Ishak Neeman
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Patent number: 6352729Abstract: An extract from the Melothria Indica Lou plant, which has the effect of inhibiting the release of cytokines, including Tumor Necrosis Factor-alpha, by immune response cells, such as macrophages, for the therapeutic treatment of sepsis.Type: GrantFiled: October 30, 2000Date of Patent: March 5, 2002Assignee: Ambryx Biotechnology, Inc.Inventor: David M Tsai
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Patent number: 6350476Abstract: The present invention provides compositions comprising the ingredients of plants of species of the genera Stephania, Coix, Pinellia, Prunus, Phellodendron, Sophora, Tetrapanax, Stemona, Glycyrrhiza, Tripterygium, Forsythia and Siegesbeckia, wherein such compositions have analgesic, antipyretic, and antiinflammatory properties. The present invention also provides methods of using such compositions for treating various conditions and diseases, including joint swelling, joint pain, osteoarthritis and rheumatoid arthritis.Type: GrantFiled: May 22, 2000Date of Patent: February 26, 2002Assignee: Shanxi Zhengzhon Pharmaceutical Co., Ltd.Inventor: Liping Hou
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Publication number: 20020018821Abstract: Process for purifying a red fruit extract containing anthocyanosides, according to which:Type: ApplicationFiled: August 14, 2001Publication date: February 14, 2002Inventors: Chrystele Soulier, Dominique DuFour
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Publication number: 20020012714Abstract: A composition comprising cartilage extract, grape seed extract and tomato extract was found to have remarkable anti-oxidant effect and free-radical inhibition. The tomato extract comprises lycopene. The composition which comprises a hydrophilic antioxidant, a lipophilic (hydrophobic) antioxidant, and a cartilage extract dramatically increases collagen synthesis in the dermis. Furthermore, the composition lowers collagenase activity and levels of advanced glycation end products (AGE). The signs of ageing, such as photoageing due to exposure to UV radiation, are related to the levels of collagen syntheses and free-radical oxidation. Compositions of the invention are intended for the treatment of ageing skin and the delaying of the onset of the signs of ageing in healthy skin.Type: ApplicationFiled: May 14, 2001Publication date: January 31, 2002Inventor: Bengt Krister Olson
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Publication number: 20020012710Abstract: A mixture of a pomegranate seed oil product and a pomegranate juice product and a pharmaceutical composition containing same. The mixture, which is a cancer chemopreventive, includes a pomegranate seed oil product and pomegranate juice product. The pharmaceutical composition includes physiologically active amounts of pomegranate seed oil product, a pomegranate juice product and a pharmaceutically acceptable carrier. According to some disclosed embodiments, a pomegranate peel product is further included. Further disclosed is a selective estrogen receptor modulator and other biologically active compounds derived from pomegranates as well as methods of use thereof.Type: ApplicationFiled: May 18, 2001Publication date: January 31, 2002Applicant: RIMONEST LTD.Inventor: Ephraim Philip Lansky
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Publication number: 20020009510Abstract: The present invention is concerned with nutritional or pharmaceutical compositions containing an extract or concentrate of a plant from the genus Lycopersicon. The compositions of the invention are useful for the treatment or prophylaxis of diseases or conditions which are characterized by increased bone resorption, such as Paget's disease, tumor-induced bone disease or particularly osteoporosis.Type: ApplicationFiled: April 3, 2001Publication date: January 24, 2002Inventor: Roman Conrad Muhlbauer
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Patent number: 6340480Abstract: A composition and method for treating circulatory conditions by promoting systemic vascular relaxation and dilation. Exemplary circulatory conditions are disclosed and include wound healing and/or reduction of hypertension. The composition is a natural combination of L-arginine, ginseng and Zizyphi fructus in an orally or topically administered dosage. The combination works synergistically to synthesize NO and thereby promote systemic vascular relaxation and dilation. The mechanism works in the wound compartment to promote and sustain the wound healing process. Likewise, the combined constituents, when administered orally or topically in proper concentration, work to maintain a critical threshold level of NO in areas that cannot themselves produce it, thereby promoting systemic vascular relaxation and dilation in order to reduce hypertension.Type: GrantFiled: December 28, 1999Date of Patent: January 22, 2002Inventors: Melvin J. Duckett, Kyle Moore
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Publication number: 20020006411Abstract: The anti-viral vaccine of the present invention is produced in transgenic plants and then administered through standard vaccine introduction method or through the consumption of the edible portion of those plants. A DNA sequence encoding for the expression of a surface antigen of a viral pathogen is isolated and ligated to a promoter which can regulate the production of the surface antigen in a transgenic plant. This gene is then transferred to plant cells using a procedure that results in its integration into the plant genome, such as through the use of an Agrobacterium tumenfaciens plasmid vector system. Preferably, the foreign gene is expressed in an portion of the plant that is edible by humans or animals. In a preferred procedure, the vaccine is administered through the consumption of the edible plant as food, preferably in the form of a fruit or vegetable juice which can be taken orally.Type: ApplicationFiled: August 9, 2001Publication date: January 17, 2002Inventors: Charles Joel Arntzen, Dominic Man-Kit Lam