Monomer Contains Oxygen Patents (Class 424/78.37)
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Patent number: 6365697Abstract: The present invention relates to water-soluble or water-dispersible polyurethanes of a water-dispersible polyurethane prepolymer having terminal isocyanate groups and a primary or secondary amine having at least one ionogenic or ionic group, and to the salts thereof. The novel polyurethanes can be used as auxiliaries in cosmetology and pharmacy and, in particular, as hair lacquers having enhanced ease of washoff.Type: GrantFiled: April 29, 1998Date of Patent: April 2, 2002Assignee: BASF AktiengesellschaftInventors: Son Nguyen Kim, Karin Sperling
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Publication number: 20020037310Abstract: A method of treating living tissue includes applying to living tissue a biocompatible adhesive composition, where the adhesive composition contains at least one alkyl ester cyanoacrylate monomer and a polymerization initiator or accelerator, wherein the polymerization initiator or accelerator is a quaternary amine, or where the adhesive composition contains a mixture of two monomer species having different absorption rates.Type: ApplicationFiled: August 2, 2001Publication date: March 28, 2002Applicant: Closure Medical CorporationInventors: Jerry Y. Jonn, John Bobo, Julian Quintero, Jon P. Moseley, Dennis D. Burns
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Patent number: 6362161Abstract: The present invention relates to an improved composition of copolymer-1 comprising copolymer-1 substantially free of species having a molecular weight of over 40 kilodaltons.Type: GrantFiled: February 22, 2000Date of Patent: March 26, 2002Assignee: Yeda Research & Development Company LimitedInventors: Eliezer Konfino, Michael Sela, Dvora Teitelbaum, Ruth Arnon
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Publication number: 20020034493Abstract: Disclosed are methods for treating endoleaks arising from endovascular repair of abdominal aortic aneurysms. The disclosed methods involve the in situ sealing of endoleaks after placement of an endovascular prostheses in the abdominal aorta. Sealing of endoleaks is achieved by injection of either a biocompatible polymer or prepolymer fluid composition into the endoleak which composition in situ solidifies to seal the leak. Preferably, the biocompatible fluid composition comprises a contrast agent to allow the clinician to visualize the sealing process.Type: ApplicationFiled: September 12, 2001Publication date: March 21, 2002Inventors: Charlie Ricci, Bart Dolmatch, Andrew H. Cragg, Richard J. Greff
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Patent number: 6358501Abstract: The present invention relates to polypeptide-polysiloxane copolymers, to their preparation by thermal copolymerization of amino acids with organofunctional polysiloxanes, and to their use as interface-active substances.Type: GrantFiled: October 15, 1999Date of Patent: March 19, 2002Assignee: Goldschmidt GmbHInventors: Thomas Dietz, Peter Lersch, Christian Weitemeyer
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Publication number: 20020026027Abstract: The present invention relates to new polyamide oligomers. These oligomers can be conjugated to lipids, nucleic acids, peptides, proteins, etc. The oligomer-lipid conjugates can be used to form liposomes, virusomes, micelles, etc., optionally containing drugs or biological agents. The polyamide oligomers are heterobifunctional allowing the attachment of other suitable ligand compounds (e.g., a targeting moiety). In addition, methods of use for the liposomes, virusomes, micelles, etc., are provided.Type: ApplicationFiled: August 30, 2001Publication date: February 28, 2002Inventor: Steven Michial Ansell
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Patent number: 6350434Abstract: Hair spray compositions containing a carboxylated polyurethane resin, and having a low volatile organic content, are disclosed. The compositions have a low viscosity, and can be applied as a pump spray or as an aerosol, to hold the hair and impart excellent hair set retention properties. The hair spray compositions can be used with a curling iron or a blow dryer to style the hair.Type: GrantFiled: November 9, 1999Date of Patent: February 26, 2002Assignee: Helene Curtis, Inc.Inventors: Darshna Bhatt, Ramiro Galleguillos, Ken Nelson, Murray H. Reich
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Publication number: 20020022014Abstract: Compositions and methods are disclosed for delousing warm-blooded animals, in need thereof, including humans. The compositions include either a water-soluble polyalkylene glycol or a water-soluble polyalkylene oxide mixed with a polymer or copolymer comprising polyalkylene oxide having carboxylic acid-containing residues. Methods of the invention include topical application to a hair-bearing surface of an effective amount of a composition of this invention, and maintaining the same on the surface for a sufficient period of time to delouse the surface. Further optional steps include washing or rinsing the composition from the surface, as well as combing the hair associated with the treated surface.Type: ApplicationFiled: December 5, 1997Publication date: February 21, 2002Inventor: THOMAS BELL
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Publication number: 20020015692Abstract: Disclosed is a solution that comprisesType: ApplicationFiled: May 22, 2001Publication date: February 7, 2002Inventors: Ramesh Krishnamurti, Sandor Nagy, Qi Wang, Habib Hichri
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Patent number: 6342476Abstract: The present invention relates to an improved composition of copolymer-1 comprising copolymer-1 substantially free of species having a molecular weight of over 40 kilodaltons.Type: GrantFiled: February 22, 2000Date of Patent: January 29, 2002Assignee: Yeda Research & Development Company LimitedInventors: Eliezer Konfino, Michael Sela, Dvora Teitelbaum, Ruth Arnon
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Patent number: 6337130Abstract: Microcapsules of a microcapsule formed of a polyurea shell wall and an encapsulated ingredient or ingredients enclosed within the wall, the wall comprising at least one oligomeric acetal having the moiety in which R is (a) a moiety containing a chain of from 5 to about 40 optionally substituted carbon atoms, (b) a moiety containing a chain of from 4 to about 40 carbon atoms and one or more internally linked oxygen or sulfur atoms or —NH-groups, or (c) an optionally substituted ethylene or propylene moiety Z is (a) an optionally substituted phenyl group, (b) an optionally substituted C1-C20 alkyl, C2-C20 alkenyl, C3-C8 cycloalkyl or C5-C8 cycloalkenyl group, or (c) benzoyl, and n is 1 if R is (a) or (b), or is 2-20 if R is (c).Type: GrantFiled: July 29, 1999Date of Patent: January 8, 2002Assignee: Zeneca LimitedInventors: Juanita Elena Van Koppenhagen, Herbert Benson Scher, Kuo-Shin Lee, Ian Malcolm Shirley, Philip Wade, Richard Follows
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Publication number: 20010053794Abstract: A method for treating a microbial infection in a mammal, such as a human, comprising treating the mammal with a therapeutically effective amount of a polymer comprising an amino group or an ammonium group attached to the polymer backbone via an aliphatic spacer group. The polymer can be a homopolymer or a copolymer. In one embodiment, the polymer is a copolymer comprising a monomer having a pendant ammonium group and a hydrophobic monomer.Type: ApplicationFiled: January 28, 2000Publication date: December 20, 2001Inventors: W. Harry Mandeville III, Thomas X. Neenan, Stephen Randall Holmes-Farley
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Patent number: 6326011Abstract: A copolymer having silyl groups with at least one reactive functional group bonded thereto. The copolymer comprises a monomer (A) shown by the following Formula (I): wherein R1 is hydrogen atom or methyl; R2 is alkylene group having 1-6 carbon atoms; and R3, R4 and R5 each is a reactive functional group which can cross-link molecules of the copolymer by hydrolyzing. Further, the copolymer preferably comprises, as a constituent monomer, an alkyl (meth)acrylate and a siloxane-containing (meth)acrylate. A coating-forming method comprises hydrolyzing the composition on a material to be treated to cross-link molecules of the copolymer when on the material. A coating of the cross-linked copolymer has resistance to washing. This coating can modify the nature of hair, improve make-up retention, and provide skin-protecting. It can impart water-repellency, resistance to fouling, suitability as a sizing and crease resistance to fibers.Type: GrantFiled: January 28, 1999Date of Patent: December 4, 2001Assignee: Shiseido Co., Ltd.Inventors: Kazuyuki Miyazawa, Toshio Yanaki, Fumiaki Matsuzaki
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Patent number: 6322803Abstract: A method for creating an wood destroying organism resistant coating is disclosed. The method involves spraying a structure with a mixture of a quick setting liquid monomer and a pesticide. The monomer, when cured, forms a bonded polyurethane coating upon the surface a structure which slowly releases pesticide over long periods of time. The method may be practiced as a two part system utilizing monomers and catalytic curing agents, and a one part system utilizing masked isocyanates.Type: GrantFiled: July 3, 1999Date of Patent: November 27, 2001Assignee: Bioguard Technologies, Inc.Inventors: Peter Van Voris, Dominic A. Cataldo, Edward S. Lipinsky
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Publication number: 20010038831Abstract: A superporous hydrogel composite is formed by polymerizing one or more ethylenically-unsaturated monomers, and a multiolefinic crosslinking agent, in the presence of particles of a disintegrant and a blowing agent. The disintegrant, which rapidly absorbs water, serves to greatly increase the mechanical strength of the superporous hydrogel and significantly shorten the time required to absorb water and swell. Superporous hydrogel composites prepared by this method have an average pore size in the range of 10 &mgr;m to 3,000 &mgr;m. Preferred particles of disintegrant include natural and synthetic charged polymers, such as crosslinked sodium carboxymethylcellulose, crosslinked sodium starch glycolate, and crosslinked polyvinylpyrrolidone. The blowing agent is preferably a compound that releases gas bubbles upon acidification, such as NaHCO3. Improved hydrogel composites formed without a blowing agent are also provided.Type: ApplicationFiled: March 16, 2001Publication date: November 8, 2001Inventors: Kiham Park, Haesun Park
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Publication number: 20010031271Abstract: The present invention refers to a cosmetic powder whose coating includes polymers or co-polymer belonging to the Poly Alpha Hydroxi Acids family, to a cosmetic composition that contains it and to the process of preparation of the powder.Type: ApplicationFiled: March 8, 2001Publication date: October 18, 2001Inventor: Nadia Avalle
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Patent number: 6299905Abstract: Improved matrices for tissue repair comprising a biocompatible, bioerodable polymer which has a water solubility of about 0.01 to about 500 mg/mL at about 25° C. and adhesive strength of about 600 to about 150,000 Pa; and pressure sensitive adhesives for tissue repair which have adhesive strength of about 600 to about 150,000 Pa. The matrix or adhesive can further comprise a filler or a bioactive agent, or both. The matrices and adhesives are tissue-adherent and dough-like so they can be molded to fit a repair site. When used for bone/implant fixation, or as a filler for bone or cartilage repair, gradual short-term bioerosion of the adhesive matrix allows it to be replaced with developing bone or cartilage tissue. When used for release of a bioactive agent, the agent can be mixed into the adhesive matrix well before the implantation procedure. After implantation, the bioactive agent is gradually released as the adhesive matrix biodegrades.Type: GrantFiled: April 16, 1996Date of Patent: October 9, 2001Assignee: DePuy Orthopaedics, Inc.Inventors: Dale R. Peterson, Z. David Deng, Todd P. Glancy
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Patent number: 6280745Abstract: The present invention provides a composition comprising one or more constitutive polymers and modifier polymers and/or hydrophilic co-surfactants useful for reducing adhesions or delivering bioactive agents. Methods for preventing and/or reducing post-surgical adhesions or delivering bioactive agents are provided.Type: GrantFiled: June 22, 2000Date of Patent: August 28, 2001Assignee: Alliance Pharmaceutical Corp.Inventors: Stephen G. Flore, Luis A. Dellamary, Lorraine E. Reeve, Jeffry G. Weers
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Patent number: 6277889Abstract: A molluscicide containing a non-toxic animal repellant and metaldehyde, in which the molluscicidal efficacy of the molluscicide greater than that of the molluscicide if it did not contain repellant. The repellant may be an anthranilate compound or d-pulegone which present at a concentration of up to 1%.Type: GrantFiled: November 12, 1999Date of Patent: August 21, 2001Inventor: Ivor Bowen
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Publication number: 20010012511Abstract: The present invention describes a method of preventing adhesion formation between tissues in an animal by placing a sterile polyoxaester adhesion prevention barrier between the tissues of the animal to prevent an adhesion from forming.Type: ApplicationFiled: February 9, 2001Publication date: August 9, 2001Inventors: Rao S. Bezwada, Dennis D. Jamiolkowski
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Patent number: 6271264Abstract: The present invention relates to a method for sequestering bile acids in a patient and to particular polymers for use in the method. The method comprises administering a therapeutically effective amount of a spirobicyclic ammonium moiety-containing polymer composition to a mammal, such as a human, whereby bile acids are sequestered. The polymers of the invention comprise spirobicyclic ammonium moieties and optionally, further comprise a hydrophobic substituent, a quaternary ammonium-containing substituent or a combination thereof.Type: GrantFiled: December 1, 1998Date of Patent: August 7, 2001Assignee: GelTex Pharmaceuticals, Inc.Inventors: Pradeep K. Dhal, Steven C. Polomoscanik
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Patent number: 6267952Abstract: The invention features a method for treating obesity in a patient by administering to the patient a polymer that has been substituted with one or more groups that inhibit lipases, which are enzymes responsible for the hydrolysis of fat. The invention further relates to the polymers employed in the methods described herein as well as novel intermediates and methods for preparing the polymers.Type: GrantFiled: October 5, 1998Date of Patent: July 31, 2001Assignee: GelTex Pharmaceuticals, Inc.Inventors: W. Harry Mandeville, III, Molly Kate Boie, Venkata R. Garigapati
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Publication number: 20010009676Abstract: The present invention provides a method of attenuating the formation of a bruise and a method of attenuating swelling or inflammation in the tissue of a patient via applying a composition comprising a hydrophilic foam substrate and a polymeric hydrophilic agent capable of absorbing water to the surface of the skin.Type: ApplicationFiled: February 20, 2001Publication date: July 26, 2001Inventors: Robert W. Sessions, Alan R. Kahn
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Patent number: 6264937Abstract: The present invention relates to a method for treating obesity, a method for reducing the absorption of dietary fat, and a method for treating hypertriglyceridemia in a patient and to particular polymers for use in the methods or in a manufacture of a medicament. The methods comprise the step of orally administering to a mammal, such as a human, a therapeutically effective amount of one or more fat-binding polymers. The administration of the fat-binding polymer of the invention facilitates the removal of fat from the body prior to digestion, with minimal side effects and low toxicity. In a preferred embodiment, the one or more fat-binding polymers are administered in combination with one or more lipase inibitors, for example, lipstatin and tetrahydrolipstatin.Type: GrantFiled: October 5, 1998Date of Patent: July 24, 2001Assignee: GelTex Pharmaceuticals, Inc.Inventors: W. Harry Mandeville, III, George M. Whitesides, Stephen Randall Holmes-Farley
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Publication number: 20010006628Abstract: Transdermal drug delivery patches and methods of their production are described. The patches can be made such that the accommodate highly plasticizing drugs such as selegiline and/or the use of protonated forms of various drugs.Type: ApplicationFiled: January 5, 2001Publication date: July 5, 2001Inventors: Sharad K. Govil, Ludwig J. Weimann
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Patent number: 6221382Abstract: A sheet pack having a multi-layer moisture-permeable support including a hydrophobic layer and a hydrophilic layer, and a cosmetic substance, and a method for applying the sheet pack, including the steps of supplying moisture to skin and applying the sheet pack to the moisture-supplied skin.Type: GrantFiled: November 30, 1999Date of Patent: April 24, 2001Assignee: Kao CorporationInventors: Koichi Ishida, Manabu Kaneda, Yasuhiro Komori
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Patent number: 6214366Abstract: The present invention provides a method of arresting, preventing and/or reversing the impairment of central and peripheral nervous system function comprising reducing insoluble protein deposit burden by the administration of branched polycationic compounds and pharmaceutical compositions containing such branched polycationic compounds. The compounds used in the preferred method of the invention are branched dendritic polycations.Type: GrantFiled: June 1, 1999Date of Patent: April 10, 2001Assignee: The Regents of the University of CaliforniaInventors: Stanley B. Prusiner, Surachai Supattapone, Michael Scott
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Patent number: 6214332Abstract: Antimicrobial cyanoacrylate compositions are applied to suturable wound surfaces to close the wound surface.Type: GrantFiled: January 12, 1998Date of Patent: April 10, 2001Assignee: MedLogic Global CorporationInventors: Ian N. Askill, Richard J. Greff, Michael M. Byram
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Patent number: 6214885Abstract: The use of polymers containing &bgr;-hydroxyalkylvinylamine units, as obtainable by reacting polymers containing vinylamine units with epoxides of the formula in which R is C2-C28 alkyl, phenyl, C1-C18 alkylphenyl or C2-C18 alkenyl, as biocides.Type: GrantFiled: March 7, 2000Date of Patent: April 10, 2001Assignee: BASF AktiengesellschaftInventors: Jürgen Tropsch, Dieter Zeller, Anton Negele, Norbert Mahr, Jürgen Decker
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Patent number: 6204308Abstract: An emulsion-based method of microencapsulating an active agent wherein a water-in-oil emulsion, containing a matrix-forming polymer and an active agent, is dispersed in an aqueous external phase to form a microencapsulated product.Type: GrantFiled: March 1, 1999Date of Patent: March 20, 2001Assignee: Novartis AGInventors: Michael Ausborn, David Bodmer, Oskar Nagele, Laurent Marchal
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Patent number: 6190688Abstract: A material with excellent selective absorption of super antigens. Said material contains urea bonds or thiourea bonds and remains active even in a high protein concentration solution in the neutral region, Activity remains after sterilization. Also provided is a body fluid purifying column for eliminating or detoxification of super antigens. In addition to that, this invention provides a wound dressing material with super antigen adsorbing properties.Type: GrantFiled: March 1, 1999Date of Patent: February 20, 2001Assignee: Toray Industries, Inc.Inventors: Mayumi Fukuyama, Keishi Miwa, Kazuo Ishikawa