Abstract: Methods for preventing, reversing, ameliorating or treating dental diseases, disorders or injuries are provided. In particular, methods for preventing, reversing, ameliorating or treating dental diseases of the gingival (gums) and bone are provided. Such methods utilize novel compositions including, but not limited to, extraembryonic cytokine-secreting cells (herein referred to as ECS cells), including, but not limited to, Amnion-derived Multipotent Progenitor cells (herein referred to as AMP cells) and conditioned media derived therefrom (herein referred to as Amnion-derived Cellular Cytokine Solution or ACCS), and Physiologic Cytokine Solution (herein referred to as PCS), each alone or in combination with each other and/or other agents.

Abstract: The invention relates to a composition which comprises 1 to 80% by weight of at least one acid which has a pKa of 2 or less; a protic solvent; a complexing agent for Ca2+ ions; for use as conditioning agent for etching enamel lesions.

Abstract: A one-part, self-etching dental adhesive is disclosed. The adhesive includes a hydrolytically stable acidic adhesive monomer and a hydrolytically stable, difunctional hydrophilic monomer.

Abstract: A dental composition of the present invention includes: a polymerizable monomer (A); an amorphous filler (B) having an average particle size of 1 to 20 ?m and including silica-based fine particles and coatings of an oxide that cover the surfaces of the silica-based fine particles; and inorganic particles (C) having an average particle size of 0.1 to 1.0 ?m. The oxide contains a zirconium atom, a silicon atom, and an oxygen atom. It is preferable that the dental composition contain 50 to 400 parts by weight of the filler (B) and 100 to 400 parts by weight of the inorganic particles (C) per 100 parts by weight of the polymerizable monomer (A).

Abstract: The invention is directed to an improved dental composition useful in the repair of cavities, apex repairs, root perforations and root canals. Disclosed is a dental composition and dental composition additive which have improved handling characteristics, for example improved viscosity and setting time. The addition of effective amounts of a modified cellulose and calcium chloride to available dental repair compounds, such as mineral trioxide compound, results in the improved dental composition without affecting the other characteristics of the dental repair compound.

Abstract: The present invention provides a dental composition exhibiting both an excellent light diffusion property and excellent transparency, and having high mechanical strength and surface smoothness and gloss after polishing as a cured product and good handling properties as a paste. The present invention is a dental composition including: a polymerizable monomer (A); and an amorphous powder (B). The amorphous powder (B) has an average particle size of 1 to 20 ?m, and includes silica-based fine particles and coatings of an oxide that cover the surfaces of the silica-based fine particles. The oxide contains a zirconium atom, a silicon atom, and an oxygen atom. The difference in refractive index between the cured product of the polymerizable monomer (A) and the amorphous powder (B) is 0.005 to 0.03.

Abstract: Dental compositions and disulfide monomers described. The disulfide monomer comprises a disulfide backbone group wherein each of the sulfur atoms are bonded to a group terminating with an ethylenically unsaturated norbornyl group; and at least one other monomer comprising at least two ethylenically unsaturated groups.

Abstract: Dental compositions comprising a polymerizable compound, filler system of nanometer-sized silica particles, and polymerization system capable of being activated by light are provided. The compositions further contain a solvent such as a mixture of 1-butanol and acetone and may contain water. The nanometer-sized silica particles, having an average particle size of about 1 nm to about 100 nm, are uniformly dispersed within the resin. The compositions can be applied as a polish, sealant, bleach guard, or other coating material to the surfaces of dental restorations and teeth. Self-etching and non-self-etching compositions are provided. The cured coating forms a protective, durable film that enhances the shine and luster of the restorations and teeth.

Abstract: A method for infiltration and/or sealing of hard tooth tissue and for detection of caries in the infiltrated region or under the seal by means of fluorescence, is described. The method includes applying a composition comprising a filler system consisting of or comprising inorganic filler particles surface-modified by means of organic structural elements, wherein the organic structural elements can be reacted with an organic binder system to form covalent bonds, wherein the filler particles of the composition have an average particle size in the range between 1 nm and 150 nm, and an organic binder system comprising one or more polymerizable monomers, wherein the filler system is dispersed in the organic binder system (b). The infiltrated or sealed surface of the hard tooth tissue is then irradiated with excitation radiation which causes emission of fluorescence radiation. The fluorescence radiation data is recorded and used to detect curies.

Abstract: Polymerizable dental material which contains (a) at least one radically polymerizable compound according to the general formula I (b) initiators for radical polymerization; and (c) filler.

Abstract: Disclosed are photopolymerizable compositions suitable for uses such as dental composite resins, and that comprise (A) a radical-polymerizable monomer, (B) a photopolymerization initiator that comprises (B1) an ?-diketone compound, (B2) a photoacid generating agent, (B3) an aromatic amine compound, and (C) an organic filler containing a phthalate ester fluorescent agent.

Abstract: The present invention provides a dental polymerizable composition which has excellent handling property by the brush-dip technique and the bulk-mix technique, particularly excellent handling property by the brush-dip technique, contains few air bubbles, is excellent in color tone, polishability, mechanical properties and the discoloration resistance of a cured product at the time of curing and is used for many purposes such as the repair of a denture base or artificial tooth, a tooth crown prosthetic restoration and a temporary prosthetic restoration which is used until a bridge is completed when it is a two-composition type self-curing resin. The dental polymerizable composition comprises three different types of (meth)acrylate polymer particles, each having specific particle size characteristics and specific molecular weight characteristics.

Abstract: A filler which is surface-modified with a compound of the formula [(PG)-R1—Z]n—SP—[Y—R2-(AG)]m is particularly suitable for use in dental materials, for the preparation of adhesives, coatings and composites.

Abstract: To provide a dual curing type composite resin for core build-up having improved curing property by chemical polymerization with improved mechanical strength of a cured body under the condition of no light irradiation and with a shortened setting time, the composite resin is composed of a first component including a (meth)acrylate polymerizable resin and an organic peroxide, and a second component including (meth)acrylate polymerizable resin and a reducing agent, a photopolymerizaton initiator and a filler are included in the first component and/or the second component, and oxide powder of a Group II element in the periodic table having an average particle diameter of 1 ?m or less is blended in the first component and/or the second component.

Abstract: The device includes a shim component constructed for use in the non-surgical treatment of interproximal carious dental lesions. A plunger may be provided for driving substances through a tube-like channel or bore in the shim component, or an electromagnetic energy-transmissive material may fill the channel, in either case for delivering to the site of the lesion a medium that is effective for directly or indirectly killing, or biologically damaging, the carious bacteria.

Abstract: In accordance with an aspect of the invention, a medical method of affixing an element to a surface of dentine, tooth enamel, bone tissue, or corresponding substitute material is provided, the method comprising the steps of: Providing an attachment composition, the attachment composition comprising a mixture of: A thermoplastic component; and A hardenable (for example curable) component, the hardenable component being different from the thermoplastic component; Positioning the attachment composition relative to the surface of dentine, tooth enamel, bone tissue, or corresponding substitute material; and Activating the attachment composition to attach to the surface or to attach to the element positioned relative to the surface; Wherein the step of activating the attachment composition comprises activating the attachment composition by means of mechanical vibration.

Abstract: The invention relates to a dental composition comprising a) a hardenable compound (A1), b) a filler (B1), c) an initiator (C1) being able to initiate curing of compound (A1), compound (A1) having the structure A-(-S1-U-S2-MA)n, with A being a connector element, S1 being a spacergroup comprised of units connected with each other and comprising at least 4 units, S2 being a spacergroup comprised of units connected with each other and comprising at least 4 units, U being an urethane, an amide or an urea group connecting spacergroups S1 and S2, MA being an acrylate or methacrylate group and n being 3 to 6. The invention also relates to a process of producing this dental composition and using the dental composition e.g. as a temporary and/or long term crown and bridge material.

Abstract: Dental compositions and disulfide monomers are described. The disulfide monomer comprise a disulfide backbone group wherein each of the sulfur atoms are bonded to an ethylenically unsaturated group via a divalent linking group and the linking group comprises at least one heteroatom; and at least one other monomer ethylenically unsaturated monomer.

Abstract: Dental compositions and disulfide monomers described. The disulfide monomer comprises a disulfide backbone group wherein each of the sulfur atoms are bonded to a group terminating with an ethylenically unsaturated norbornyl group; and at least one other monomer comprising at least two ethylenically unsaturated groups.

Abstract: A method of dispensing a hardenable dental composition comprising 1) providing a two-part hardenable dental composition, and 2) extruding the composition through a static mixer in fluid communication with a first reservoir containing the first part and a second reservoir containing the second part, wherein a plunger is positioned in each reservoir for simultaneously forcing both parts into the static mixer, extruding the composition through the static mixer, and dispensing the composition, and wherein an extrusion force is applied to the plunger for extruding the composition through the static mixer without the aid of a mechanical advantage provided by an attached or external device. Also disclosed is a method of bonding a prosthetic device to a dental structure using the dispensing method, a device for dispensing the composition using the dispensing method, a kit comprising the device, and the composition used in the dispensing method.

Abstract: A periodontal structure regeneration composition for treatment of periodontal disease is a mixture of particles of a bone growth material and free collagen. All particles are sized to be less than 1 mm in diameter. The periodontal regeneration composition is injected into the periodontal pocket through an 18 gauge needle. The composition may contain a thickener that increases the viscosity of the composition after the material has been injected into the periodontal pocket. The composition is available in pre-filled syringes offered in a kit that may also contain strips of surgical sponge or gauze that are sized to fit within a periodontal pocket, a tube of adhesive, a dental bur, a probe, a gauze placement tool, gauze counter and a brush for cleaning the dental bur.

Abstract: A glass thread adapted for reinforcing polymeric materials includes a plurality of filaments having a chemical composition that includes the following constituents within the limits defined below in weight percent: SiO2 40 to 60 Al2O3 0 to 5 CaO 1 to 15 MgO 1 to 15 BaO 2 to 15 SrO 12 to 20 ZnO 0.5 to 10 Na2O + K2O + Li2O 0 to 5 TiO2 3 to 20 Prosthetic members including such threads are also described.

Abstract: A dental adhesive composition comprising (i) at least one non-acidic polymerizable monomer having at least one ethylenically unsaturated group, (ii) optionally one or more acidic compounds, (iii) at least one photoinitiator, (iv) at least one solvent, and (v) about 0-40% by weight of one or more fillers; wherein the weight ratio of non-acidic polymerizable monomers/acidic compounds in the adhesive composition is more than about 4.5; the viscosity of the adhesive composition is less than about 350 centipoise (cP) at 25° C.; and the adhesive composition excluding solvent and filler has an acid number of less than about 0.75 mmol NaOH/g. The dental adhesive composition is used with a dental primer composition, which may be provided together in a kit.

Abstract: A novel amorphous divalent metal ion salt for enhancing the manageability of a Portland cement and its application in dental field are disclosed. Typical formula (I), (II), or (III) of this amorphous metal ion salt are shown as following: M 2 + ? A x - ? B 2 - x - ( I ) M 2 + ? A y 2 - ? C ( 4 - y ) 4 2 - ( II ) M 2 + ? A z 3 - ? D ( 6 - z ) 9 3 - ( III ) wherein, M2+, A?, B?, C?2, D?3, x, y, and z are defined the same as the specification. A novel tooth filling material comprises: a Portland cement, a bone substitute substance, and an amorphous divalent metal ion salt with formula of (I), (II), or (III). In addition, a novel root canal filling material comprises: a Portland cement, a radiopaque substance, and an amorphous divalent metal ion salt with formula of (I), (II), or (III).

Abstract: A reaction-curable adhesive composition exhibiting acidity is formed form a weakly acidic to alkaline composition (I) comprising (a) a polymerizable monomer and (b) a compound represented by the following formula (I) and a strongly acidic composition (II) comprising (a) a polymerizable monomer. R1—C6H4—NR2CH2COOR3??(1) wherein R1 and R2 are each independently a hydrogen atom or an alkyl group which may have a functional group, and R3 is a hydrogen atom or a metal atom. The composition containing the polymerizable monomer can be stably stored for a long period of time.

Abstract: A radically curable polyurethane composite for dental restorations, including provisional restorations, includes polyurethane dimethacrylate prepolymers that have at least one flexible unit within a polyurethane dimethacrylate backbone, and one or more dimethacrylate monomers. Composite materials made with polyurethane dimethacrylate prepolymers of the invention exhibit superior and optimal properties of flexural strength and deflection-at-break relative to conventional dental resin composites. Composite materials of the invention also provide improved melt-resistance in response to the heat of grinding or finishing, thereby improving the fit of restorations made from the composite and preserving the finishing instruments. Methods of treating a tooth using the radically curable polyurethane composite and methods of making the polyurethane dimethacrylate prepolymers with flexible units is also provided. A kit including the radically curable polyurethane composite is also described.

Abstract: The present application provides dental fillers, and methods of making and using dental fillers that include a treated surface that includes a caseinate. Dental compositions including such dental fillers can be useful for delivering ions to the oral environment. Dental compositions, and methods of using dental compositions that include a caseinate and a hardenable resin or a water-dispersible, polymeric film former are also provided.

Abstract: The invention concerns dental compositions. Said composition comprises (1) a silicone crosslinkable and/or polymerizable by cationic process; (2) an efficient amount of at least an initiator such as an organometallic complex borate; and (3) a dental filler present in the composition in a proportion of at least 10 wt. % relative to the composition total weight. Said dental compositions are useful for making dental prostheses or for dental restoration.

Abstract: To provide a polymerizable composition having more excellent preservation stability of pastes than a conventional composition using a combination of a copper compound, cumene hydroperoxide, and N-acetylthiourea, and having a polymerization curing time which does not change with time, that is, does not delay or quicken from a time set for a product even though the composition is stored, the polymerizable composition includes a first paste and a second paste, wherein the first paste includes a polymer of ?-? unsaturated monocarboxylic acid or ?-? unsaturated dicarboxylic acid, water, and a hydroperoxide as a peroxide, and the second paste includes a (meth)acrylate compound not having an acid group, fluoroaluminosilicate glass powder, a thiourea derivative as a reducing material, and a vanadium compound as a polumerization accelerator.

Abstract: The object of this invention relates to a procedure for treatment, both preventive and corrective, of dental cavities. Said procedure consists fundamentally in irradiation of the dental surface to be treated with a Neodymium YAG laser in conformity with specific parameters and conditions, signifying an advance in respect of the state of the art in this field. In the case of the treatment of cavities for corrective purposes it is also necessary, among other stages, to apply a dental cementing and restorative biomaterial on the surface of the dental enamel or on the dentin in such a manner that irradiation by the laser produces microfusion between both thereof. The present invention also relates to the biomaterial used in the procedure described herein, preferentially based on hydroxyapatite, together with the use of the procedure and of the biomaterial in the treatment of dental cavities.

Abstract: Compositions and methods of their use to adhere a variety of materials together are disclosed herein. The compositions include at least tetra calcium phosphate, an effective amount of a compound that is structurally similar to phosphoserine, and can be mixed with an aqueous solution. The compositions provide adhesive and cohesive strength in both wet and dry environments and exhibit significant bond strength upon curing.

Abstract: The present invention generally relates to chemically bonded ceramic biomaterials, preferably a dental material or an implant material, comprising two binder systems. The main binder system forms a chemically bonded ceramic upon hydration thereof, and comprises powdered calcium aluminate and, optionally, minor amounts of calcium silicate. The second binder system is a cross-linking organic binder system which provides for initial crosslinking of the freshly mixed paste forming the biomaterial. The biomaterial also comprises inert filler particles.

Abstract: A method of manufacturing a dental post according to the present invention comprises the steps of: (i) overjacketing extrusion of at least one thermoplastic material over at least one filament or yarn, such that the thermoplastic material cross-sectionally enwraps the at least one filament or yarn; (ii) solidifying the extruded product of step (i); (iii) equipping the solidified extruded product of step (ii) with a surface texture, such that the thermoplastic wrapping is not modified in a way as to expose or damage the at least one filament or yarn. The invention allows for more flexibility in the manufacturing of dental posts, especially in generating surface textures of such dental posts.

Abstract: A method for formation of spherical particles of ion substituted calcium phosphate. The method is based on precipitation of particles from a buffered solution under static, stirring or hydrothermal conditions. Also, the use of the formed materials and the particles in itself.

Abstract: Zirconium-containing BaO- and PbO-free X-ray opaque glasses having a refractive index nd of about 1.480 to about 1.517 and a high X-ray opacity with an aluminum equivalent thickness of at least about 180% are provided. Such glasses are based on a SiO2—B2O3—Cs2O—K2O—La2O3 system with additions of Al2O3, Li2O, Na2O and/or ZrO2. Such glasses may be used, in particular, as dental glasses or as optical glasses.

Abstract: A dental material is provided that exhibits a color change upon or after mixing or contacting components of the composition. The composition includes an acidic component in one part, and a basic component in another part that upon contact with the acidic component initiates a chemical reaction thereof that alters the pH of the composition. An acid or base sensitive color change agent is present in the composition that registers the change in pH by changing color as the pH changes.

Abstract: Certain novel polymerizable phosphoric acid derivatives (hereinafter referred to as monomers) comprising a polyalicyclic structure element, mixtures comprising one or a plurality of these compounds and corresponding curable blends and products as well as their respective use as a dental material or for the preparation of a dental material are described. The compounds are eminently suitable as bonding agents, in particular in dental adhesive materials. A process for preparing these compounds or mixtures and a method for preparing a product, preferably a product suitable for dentistry, are also described.

Abstract: Zirconium-containing BaO- and PbO-free X-ray opaque glasses having a refractive index nd of about 1.54 to about 1.58 and a high X-ray opacity with an aluminum equivalent thickness of at least about 500% are provided. Such glasses are based on a SiO2—B2O3—Al2O3—R2O—RO—La2O3—ZrO2 system with optional additions of SnO2. Such glasses may be used, in particular, as dental glasses or as optical glasses.

Abstract: Lithium silicate materials are described which can be easily processed by machining to dental products without undue wear of the tools and which subsequently can be converted into lithium silicate products showing high strength.

Abstract: Disclosed herein are curable (meth)acrylate resins for dental compositions obtained by reacting an anhydride with an alcohol or an amine to obtain a carboxy ester or a carboxy amide and reacting the carboxy ester or carboxy amide with a (meth)acrylate monomer comprising an epoxide group or an oxetane group.

Abstract: A dental restorative composition comprises: (A) polymerizable monomer(s) selected from hydroxyethyl (meth)acrylate phosphate, hydroxypropyl (meth)acrylate phosphate, hydroxybutyl (meth)acrylate phosphate, dipentaerythritol penta(meth)acrylate phosphate, pentaerythritol tri(meth)acrylate phosphate, phenyl (meth)acryloxyethyl phosphate, and a combination thereof; (B) polymerizable monomer(s) having a molecular weight of 100-250, at least one hydroxyl group, and at least one ethylenically unsaturated group; (C) polymerizable monomer(s) having a molecular weight of 270-900, at least two ethylenically unsaturated groups and no acidic functional group; (D) photo-initiator(s); and (E) filler(s) each having a mean particle size of more than 0.005 microns and less than 70 microns. The weight ratio of (A+B):(C) ranges from 30:70 to 90:10, and the composition has a shear bond strength of at least 10MPa to both dentin and enamel after being light-cured.

Abstract: Novel polymerizable compounds comprising a polyalicyclic structure element and certain functional groups, mixtures comprising one or a plurality of these compounds and corresponding curable blends and products as well as their respective use as dental material or for the preparation of a dental material are described. A method for preparing these compounds or mixtures and a method for preparing a product, preferably a product suitable for dentistry, are also described.

Abstract: A composite material and method of making and using the same is described. In particular a dental (and preferably photocurable) composite material, and the use of a composite material according to the invention as a dental material and a method for preparation of a composite material according to the invention. Also disclosed are novel radically polymerizable monomers comprising at least one polyalicyclic structure element and certain ethylenic structure elements, which are particularly suitable for use in a composite material according to the invention.

Abstract: Embodiments described herein are related to fillers that are placed within an extraction site in need of bone augmentation and preservation. The fillers encourage sufficient new bone growth in order that normal jaw bone deterioration following tooth removal is prevented. The fillers create, arrange, and assemble an ideal growth environment for new bone growth to rapidly grow and preserve the original contours of an individual's jaw bone. Further embodiments described herein are related to dental implants that are arranged to provide a scaffold upon which a damaged or missing dental papilla may regrow. The dental implants may include a micro-pattern to facilitate directional cell growth.

Abstract: The invention relates to a curable composition comprising addition curable silicone component (A) having a linear siloxane backbone at least one unsaturated, non-activated side group pendant from the Si atom or atoms in the backbone, component (A) having an equivalent weight in the range of about 68 to about 1000, crosslinker component (B) comprising at least 2 SiH groups, catalyst component (C) being able to catalyse the reaction between component (A) and component (B), filler component (D), wherein the equivalent weight is defined as (molecular weight of the molecule)/(number of unsaturations in the molecule).

Abstract: A composition of macrocyclic oligomer with at least one (meth)acrylate polymerizable group. A method includes preparing an activated precursor of an oligomer at pseudo high-dilution conditions. A method also includes preparing an activated precursor of an oligomer by reacting the precursor with an activated coupling agent, wherein the precursor is condensable and polymerizable.

Abstract: There are provided a novel polymerizable composition having an X-ray contrast property and excellent transparency, a cured product thereof, and a composite material comprising powder of the cured product. More specifically, there are provided a polymerizable composition comprising (A) an inorganic oxide having an X-ray contrast property and an average particle diameter of 100 nm or smaller, (B) a surface modifier, (C) a polymerizable compound and (D) a polymerization initiator, a cured product obtained by polymerizing these components, and a composite material comprising powder of the cured product.

Abstract: The invention relates to a composition which is self-adhesive to the hard tooth tissue, comprising: (A) 5 to 75 percent by weight of one or more mono or higher functional ethylenically unsaturated compounds which additionally have an acid functional group, wherein one of said compounds has a P—OH group, for instance a phosphoric, phosphonic or phosphinic acid group; (B) 2 to 50 percent by weight of one or more mono or higher functional ethylenically unsaturated compounds without any acid functional group; (C) 22.8 to 85 percent by weight of filling material(s), comprising at least one filling material that may react with component (A) in the sense of causing a ion exchange, neutralization, salt formation and/or chelate formation reaction; (D) 0.1 to 8 percent by weight of one or more initiators and optionally activators; (E) 0.1 to 20 percent by weight of further additives, for example, modifiers, wherein the weight ration in % of component (A) relative to component (B) ranges from 21 to 90: 10 to 79.

Abstract: Presently described are dental adhesive compositions and methods of use. The dental adhesive compositions described herein comprises a major amount of a hardenable component comprising a polymerizable organic component (i.e. having ethylenically unsaturated moieties) and a minor amount of a (e.g. water dispersible) polymer that comprises repeating units comprising polar or polarizable groups and repeating units comprising hydrophobic hydrocarbon groups.

Abstract: A composition for dental use containing a polymerizable monomer (a) having an aromatic ring and a hydroxyl group, a polymerizable monomer (b) having an aromatic ring without having any hydroxyl groups, and a polymerizable monomer (c) other than the polymerizable monomers (a) and (b), wherein the composition for dental use contains the polymerizable monomers (a), (b), and (c) in an amount of from 10 to 30% by weight, from 50 to 70% by weight, and from 10 to 30% by weight, respectively, of all the polymerizable monomers. The composition for dental use of the present invention can be suitably used as a product capable of substituting a part or all of a natural tooth in the field of dental therapy.