Micromonospora Chalcea Patents (Class 435/868)
  • Antitumor antibiotics (LL-E33288 complex)
    Patent number: 5108912
    Abstract: Antibacterial and antitumor agents designated LL-E33288 complex and their production by new strains of Micromonospora echinospora spp. calichensis NRRL-15839, NRRL-15975 and NRRL-18149, are disclosed.
    Type: Grant
    Filed: September 10, 1990
    Date of Patent: April 28, 1992
    Assignee: American Cyanamid Company
    Inventors: May D. Lee, Michael Greenstein, David P. Labeda, Amedeo A. Fantini
  • Process for producing neuraminidase
    Patent number: 4710470
    Abstract: Neuraminidase is produced by culturing a neuraminidase producing microorganism belonging to the genus Micromonospora. The neuraminidase is useful for the quantitative determination of a sialic acid-containing substance in a sample.
    Type: Grant
    Filed: August 1, 1984
    Date of Patent: December 1, 1987
    Assignee: Kyowa Hakko Kogyo Co., Ltd.
    Inventors: Takayuki Uwajima, Kazuo Aisaka
  • Process for the production of 7-deazaadenosine and 7-deazainosine
    Patent number: 4316957
    Abstract: The antibacterial compounds 7-deazaadenosine and 7-deazinosine are produced by fermentation of a new microorganism of the genus Micromonospora. At least one of the active substances is isolated from the culture medium.
    Type: Grant
    Filed: April 4, 1978
    Date of Patent: February 23, 1982
    Assignee: Abbott Laboratories
    Inventors: Takashi Nara, Ryo Okachi, Isao Kawamoto, Tomoyasu Sato, Tetsuo Oka
  • .beta.-Lactamase inhibitor EM4615
    Patent number: 4205068
    Abstract: A substance which inhibits the enzyme .beta.-lactamase, produced by a wide range of microorganisms, is obtained when species of the microorganism Micromonospora are cultivated under aerobic fermentation conditions and this inhibitor can be isolated from the fermentation medium by extraction. This substance, denominated EM4615, is useful to enhance the effectiveness of .beta.-lactam antibiotics such as penicillins and cephalosporins.
    Type: Grant
    Filed: May 18, 1978
    Date of Patent: May 27, 1980
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Richard B. Sykes, J. Scott Wells, Pacifico A. Principe, Wen C. Liu