Streptomyces Platensis Patents (Class 435/903)
  • Patent number: 5443972
    Abstract: New compounds, which we have named the "Leustroducsins" have the formula (I): ##STR1## in which R represents a 5-methylhexanoyloxy group, a 6-methyloctanoyloxy group or a 7-methyloctanoyloxy group, and salts thereof, and may be prepared by fermentation using a microorganism of the genus Streptomyces, especially a strain of the species Streptomyces platensis, such as strain SANK 60191 (FERM BP-3288). These compounds may be used for the treatment or prophylaxis of: adverse reactions resulting from cancer chemotherapy or radiotherapy; infections; cancer; cerebral dysfunction; and fungal infections.
    Type: Grant
    Filed: May 6, 1994
    Date of Patent: August 22, 1995
    Assignee: Sankyo Company, Limited
    Inventors: Takafumi Kohama, Isao Kaneko, Takemichi Nakamura, Takeshi Kagasaki, Ryuzo Enokita, Keiichi Matsuda